Gene: OR51L1

119682
OR11-31
olfactory receptor family 51 subfamily L member 1
protein-coding
11p15.4
Ensembl:ENSG00000176798 Vega:OTTHUMG00000066605 UniprotKB:Q8NGJ5
NC_000011.10
PubMed
0   ANCO-SNPs
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.861e-1 (AD)  8.553e-3 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR5A20.674
SPINT30.669
OR6C60.647
UGT1A10.617
OR51V10.61
OR5K10.609
TXNDC80.607
OR52N10.606
UGT2B280.605
HTN30.597

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC25A41-0.208
ERAS-0.195
NOG-0.184
CRLF1-0.184
DBP-0.181
C11orf49-0.18
PURG-0.177
KLKB1-0.177
CCDC175-0.176
HHATL-0.175

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000393Air PollutantsAir Pollutants analog results in increased expression of OR51L1 mRNA21757418
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of OR51L1 mRNA21298039
C006780bisphenol Abisphenol A results in decreased expression of OR51L1 mRNA25181051

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004930G-protein coupled receptor activity-IEA-  
GO:0004984olfactory receptor activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0007165signal transduction-IBA21873635  
GO:0007186G-protein coupled receptor signaling pathway-IEA-  
GO:0050911detection of chemical stimulus involved in sensory perception of smell-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
hsa04740Olfactory transduction
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-381753Olfactory Signaling PathwayTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-418555G alpha (s) signalling eventsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24015780Family-based association analysis of alcohol dependence criteria and severity. (2014 Feb)Wetherill LAlcohol Clin Exp Res