Gene: ABCC2

1244
ABC30|CMOAT|DJS|MRP2|cMRP
ATP binding cassette subfamily C member 2
protein-coding
10q24.2
Ensembl:ENSG00000023839 MIM:601107 Vega:OTTHUMG00000018895 UniprotKB:Q92887
NG_011798.2
PubMed
ND|AD
6   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.883e-1 (AD)  6.256e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF7610.661
SOAT10.656
LOXL20.655
TMEM39A0.655
UNC13D0.65
TEP10.643
DSE0.643
ZCCHC80.638
PHACTR40.636
CASP60.636

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CRH-0.465
ZSCAN1-0.392
NMU-0.374
PPEF1-0.371
ABCC12-0.368
DLX1-0.363
SLC7A4-0.362
GSG1-0.359
OSTN-0.352
HAPLN1-0.35

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00067VasopressinSmall Molecule11000-17-2ApprovedTransporter
DB00091CyclosporineSmall Molecule59865-13-3Approved|InvestigationalTransporter
DB00116Tetrahydrofolic acidSmall Molecule135-16-0NutraceuticalTransporter
DB00143GlutathioneSmall Molecule70-18-8Approved|Investigational|NutraceuticalTransporter
DB00175PravastatinSmall Molecule81093-37-0ApprovedTransporter
DB00206ReserpineSmall Molecule50-55-5Approved|InvestigationalTransporter
DB00224IndinavirSmall Molecule150378-17-9ApprovedTransporter
DB00227LovastatinSmall Molecule75330-75-5Approved|InvestigationalTransporter
DB00252PhenytoinSmall Molecule57-41-0ApprovedTransporter
DB00257ClotrimazoleSmall Molecule23593-75-1ApprovedTransporter
DB00275OlmesartanSmall Molecule144689-24-7Approved|InvestigationalTransporter
DB00286Conjugated estrogensSmall Molecule12126-59-9ApprovedTransporter
DB00300Tenofovir disoproxilSmall Molecule201341-05-1Approved|InvestigationalTransporter
DB00328IndomethacinSmall Molecule53-86-1Approved|InvestigationalTransporter
DB00345Aminohippuric acidSmall Molecule61-78-9Approved|InvestigationalTransporter
DB00365GrepafloxacinSmall Molecule119914-60-2Approved|Investigational|WithdrawnTransporter
DB00398SorafenibSmall Molecule284461-73-0Approved|InvestigationalTransporter
DB00421SpironolactoneSmall Molecule52-01-7ApprovedTransporter
DB00439CerivastatinSmall Molecule145599-86-6Approved|WithdrawnTransporter
DB00503RitonavirSmall Molecule155213-67-5Approved|InvestigationalTransporter
DB00515CisplatinSmall Molecule15663-27-1ApprovedTransporter
DB00526OxaliplatinSmall Molecule61825-94-3Approved|InvestigationalTransporter
DB00541VincristineSmall Molecule57-22-7Approved|InvestigationalTransporter
DB00563MethotrexateSmall Molecule59-05-2ApprovedTransporter
DB00564CarbamazepineSmall Molecule298-46-4Approved|InvestigationalTransporter
DB00570VinblastineSmall Molecule865-21-4ApprovedTransporter
DB00602IvermectinSmall Molecule70288-86-7Approved|InvestigationalTransporter
DB00641SimvastatinSmall Molecule79902-63-9ApprovedTransporter
DB00661VerapamilSmall Molecule52-53-9ApprovedTransporter
DB00675TamoxifenSmall Molecule10540-29-1ApprovedTransporter
DB00688Mycophenolate mofetilSmall Molecule128794-94-5Approved|InvestigationalTransporter
DB00694DaunorubicinSmall Molecule20830-81-3ApprovedTransporter
DB00695FurosemideSmall Molecule54-31-9ApprovedTransporter
DB00709LamivudineSmall Molecule134678-17-4Approved|InvestigationalTransporter
DB00762IrinotecanSmall Molecule97682-44-5Approved|InvestigationalTransporter
DB00773EtoposideSmall Molecule33419-42-0ApprovedTransporter
DB00795SulfasalazineSmall Molecule599-79-1ApprovedTransporter
DB00876EprosartanSmall Molecule133040-01-4ApprovedTransporter
DB00908QuinidineSmall Molecule56-54-2Approved|InvestigationalTransporter
DB00957NorgestimateSmall Molecule35189-28-7Approved|InvestigationalTransporter
DB00958CarboplatinSmall Molecule41575-94-4ApprovedTransporter
DB00966TelmisartanSmall Molecule144701-48-4Approved|InvestigationalTransporter
DB00973EzetimibeSmall Molecule163222-33-1ApprovedTransporter
DB00977Ethinyl EstradiolSmall Molecule57-63-6ApprovedTransporter
DB00978LomefloxacinSmall Molecule98079-51-7Approved|InvestigationalTransporter
DB00997DoxorubicinSmall Molecule23214-92-8Approved|InvestigationalTransporter
DB01016GlyburideSmall Molecule10238-21-8ApprovedTransporter
DB01032ProbenecidSmall Molecule57-66-9Approved|InvestigationalTransporter
DB01045RifampicinSmall Molecule13292-46-1ApprovedTransporter
DB01076AtorvastatinSmall Molecule134523-00-5ApprovedTransporter
DB01095FluvastatinSmall Molecule93957-54-1ApprovedTransporter
DB01098RosuvastatinSmall Molecule287714-41-4ApprovedTransporter
DB01115NifedipineSmall Molecule21829-25-4ApprovedTransporter
DB01138SulfinpyrazoneSmall Molecule57-96-5ApprovedTransporter
DB01165OfloxacinSmall Molecule82419-36-1ApprovedTransporter
DB01169Arsenic trioxideSmall Molecule1327-53-3Approved|InvestigationalTransporter
DB01174PhenobarbitalSmall Molecule50-06-6Approved|InvestigationalTransporter
DB01202LevetiracetamSmall Molecule102767-28-2Approved|InvestigationalTransporter
DB01208SparfloxacinSmall Molecule110871-86-8Approved|InvestigationalTransporter
DB01229PaclitaxelSmall Molecule33069-62-4ApprovedTransporter
DB01232SaquinavirSmall Molecule127779-20-8Approved|InvestigationalTransporter
DB01234DexamethasoneSmall Molecule50-02-2Approved|InvestigationalTransporter
DB01248DocetaxelSmall Molecule114977-28-5Approved|InvestigationalTransporter
DB01268SunitinibSmall Molecule557795-19-4Approved|InvestigationalTransporter
DB01411PranlukastSmall Molecule103177-37-3Approved|InvestigationalTransporter
DB01586Ursodeoxycholic acidSmall Molecule128-13-2Approved|InvestigationalTransporter
DB01892HyperforinSmall Molecule11079-53-1NutraceuticalTransporter
DB02659Cholic AcidSmall Molecule81-25-4ApprovedTransporter
DB02703Fusidic AcidSmall Molecule6990-06-3Approved|InvestigationalTransporter
DB04100(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I)Small MoleculeExperimentalTransporter
DB04216QuercetinSmall Molecule117-39-5Experimental|InvestigationalTransporter
DB04348Taurocholic AcidSmall Molecule81-24-3ExperimentalTransporter
DB047895-methyltetrahydrofolic acidSmall Molecule134-35-0Investigational|NutraceuticalTransporter
DB06290SimeprevirSmall Molecule923604-59-5ApprovedTransporter
DB08860PitavastatinSmall Molecule147511-69-1ApprovedTransporter
DB08884Gadoxetic acidSmall Molecule135326-11-3ApprovedTransporter
DB08907CanagliflozinSmall Molecule842133-18-0ApprovedTransporter
DB09060AvibactamSmall Molecule1192500-31-4ApprovedTransporter
DB09272EluxadolineSmall Molecule864821-90-9Approved|InvestigationalTransporter
DB09374Indocyanine greenSmall Molecule3599-32-4Approved|InvestigationalTransporter
DB12070LetermovirSmall Molecule917389-32-3Approved|InvestigationalTransporter
DB00171ATPSmall Molecule56-65-5Investigational|NutraceuticalTarget
DB01138SulfinpyrazoneSmall Molecule57-96-5ApprovedTarget
ID Drug Name Action PubMed
C5179431-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone"AG 1879 inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]"25813982
C5179431-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone"Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]"25813982
C5179431-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone"[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein"25813982
C5179431-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone"Protein Kinase Inhibitors inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]"25813982
C4369441,4,7-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecane"ABCC2 protein affects the transport of 1,4,7-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecane"15967123
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased expression of ABCC2 mRNA"15833929|2249639
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC2 mRNA"15833929|1598641
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC2 protein"15986414|2781899
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC2 mRNA]"22496397
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC2 mRNA]"22698814
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC2 mRNA]"17627975
C4901661-(4-methoxyphenyl)piperazine1-(4-methoxyphenyl)piperazine results in increased expression of ABCC2 mRNA26821219
C4873661-O-(2-((2',6'-dichlorophenyl)amino)phenylacetyl)glucopyranuronic acid"ABCC2 protein affects the chemical synthesis of 1-O-(2-((2',6'-dichlorophenyl)amino)phenylacetyl)glucopyranuronic acid"25450747
C0549192,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of ABCC2 mRNA"25542188
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of ABCC2 mRNA"25510870
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mRNA]15896333
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in decreased expression of ABCC2 mRNA"24713691|2576820
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of ABCC2 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of ABCC2 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of ABCC2 mRNA"25510870
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mRNA]15896333
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of ABCC2 mRNA"25510870
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of ABCC2 mRNA"18680760
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"ABCC2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"11306678
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[Cyclosporine results in decreased activity of ABCC2 protein] which affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16356829
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"ABCC2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16611851
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"ABCC2 protein affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"15057744
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"ABCC2 protein results in increased transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"11306678
C0292162-amino-3-methylimidazo(4,5-f)quinoline"ABCC2 protein affects the transport of 2-amino-3-methylimidazo(4,5-f)quinoline"16611851
C0188552-tert-butylhydroquinone2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA11836020
C0188552-tert-butylhydroquinone2-tert-butylhydroquinone results in increased expression of ABCC2 protein11836020
C0188552-tert-butylhydroquinone2-tert-butylhydroquinone results in increased expression of ABCC2 mRNA11264000
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC2 mRNA"15833929
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ABCC2 mRNA"15833929
C0612133',4',7-trihydroxyisoflavone"3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]"22914566
C0612133',4',7-trihydroxyisoflavone"3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA"22914566
C0612133',4',7-trihydroxyisoflavone"Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]"22914566
C0612133',4',7-trihydroxyisoflavone"Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]"22914566
C0612133',4',7-trihydroxyisoflavone"CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]"22914566
C4171904-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine"4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)pyrimidine results in increased expression of ABCC2 mRNA"15673846
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of ABCC2 mRNA"25380136
C0275764-hydroxy-2-nonenal"4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"19326901
C0275764-hydroxy-2-nonenal"Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]"19326901
C0275764-hydroxy-2-nonenalABCC2 protein affects the export of 4-hydroxy-2-nonenal metabolite12623073
C0995644-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acidABCC2 protein results in increased transport of 4-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acid17724374
C0995644-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acidABCC2 protein results in increased transport of 4-((methylnitrosoamino)-1-(3-pyridyl)but-1-yl)beta-omega-glucosiduronic acid17724374
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneABCC2 protein affects the abundance of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone metabolite17724374
C0538975(6)-carboxy-2',7'-dichlorofluorescein"4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"19326901
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein"25862123
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog"27450509
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein"24973091
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]"19326901
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"19326901
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Atorvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"25862123
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"24973091
C0538975(6)-carboxy-2',7'-dichlorofluorescein"fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]"27450509
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Tobacco Smoke Pollution inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]"27450509
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 gene mutant form inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"24907646|2490764
C0538975(6)-carboxy-2',7'-dichlorofluorescein"[ABCC2 gene mutant form results in increased expression of ABCC3 protein] which results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein"24907646
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein affects the transport of 5(6)-carboxy-2',7'-dichlorofluorescein"21240898|2134128
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein"24909372
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein"24907646
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Atorvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"fluvastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"24909372
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"24909372
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"24909372
C0538975(6)-carboxy-2',7'-dichlorofluorescein"Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C0538975(6)-carboxy-2',7'-dichlorofluorescein"ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein"19326901
C0845775-carboxyfluorescein diacetateABCC2 protein alternative form results in increased abundance of 5-carboxyfluorescein diacetate22027652
C0845775-carboxyfluorescein diacetateIndomethacin inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate]16636798
C0845775-carboxyfluorescein diacetateVerapamil inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate]16636798
C0693065-chloromethylfluoresceinABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione]16049127
C0229095-methoxypsoralen5-methoxypsoralen results in decreased activity of ABCC2 protein29079042
C0229095-methoxypsoralen[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin29079042
C0229095-methoxypsoralen5-methoxypsoralen results in decreased expression of ABCC2 mRNA29079042
C0229095-methoxypsoralenIndomethacin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCC2 protein]29079042
C0229095-methoxypsoralenIndomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin]29079042
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]"27702592
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]"27702592
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]"27090119
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]"27090119
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in increased expression of ABCC2 mRNA18624906
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in increased expression of ABCC2 protein18624906
C0240986-carboxyfluoresceinABCC2 protein affects the export of 6-carboxyfluorescein11477083
C0240986-carboxyfluoresceinProbenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]11477083
C1119846-methylsulfinylhexyl isothiocyanate6-methylsulfinylhexyl isothiocyanate results in increased expression of ABCC2 protein21382770
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of ABCC2 mRNA"27160211
C0207389,10-dihydro-9,10-dihydroxybenzo(a)pyrene"9,10-dihydro-9,10-dihydroxybenzo(a)pyrene results in increased expression of ABCC2 mRNA"26238291
C023710abietic acidabietic acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]18436619
C542662AC 93253AC 93253 results in increased expression of ABCC2 mRNA25912555
D000082AcetaminophenAcetaminophen affects the expression of ABCC2 mRNA25064622
D000082AcetaminophenAcetaminophen results in decreased expression of ABCC2 mRNA21420995|2669055
D000082AcetaminophenAcetaminophen affects the expression of ABCC2 mRNA17562736
D000082Acetaminophen[Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC2 mRNA17934960
D000082Acetaminophen[Acetaminophen co-treated with Sodium Chloride] results in increased expression of ABCC2 mRNA17934960
D000082AcetaminophenAcetaminophen results in increased expression of ABCC2 mRNA15496496
D000082AcetaminophenAcetaminophen results in increased expression of ABCC2 protein16177239
D000082AcetaminophenABCC2 protein affects the export of Acetaminophen analog15860656
D000082AcetaminophenABCC2 protein affects the reaction [Acetaminophen results in increased activity of SORD protein]16271353
D000082AcetaminophenABCC2 protein affects the susceptibility to Acetaminophen16271353
D000082AcetaminophenABCC2 protein results in increased export of Acetaminophen16271353
D000082Acetaminophen[Acetaminophen co-treated with Uranium analog] results in increased expression of ABCC2 mRNA17126469
D000082AcetaminophenAcetaminophen promotes the reaction [ABCC2 protein results in increased transport of Glutathione Disulfide]15276087
D000082Acetaminophen"Acetaminophen promotes the reaction [ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione]"15276087
D000082AcetaminophenAcetaminophen results in increased expression of ABCC2 mRNA17126469
D000082AcetaminophenAcetaminophen results in increased expression of ABCC2 protein15276087
D000082AcetaminophenUranium analog promotes the reaction [Acetaminophen results in increased expression of ABCC2 mRNA]17126469
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]"22914566
D000111AcetylcysteineAcetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA]23867903
D000255Adenosine TriphosphateABCC2 protein affects the metabolism of Adenosine Triphosphate22027652
D000255Adenosine TriphosphateAdenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]24039982
D000255Adenosine Triphosphate"Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]"20060011
D000255Adenosine TriphosphateAdenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3]9794919
D000255Adenosine TriphosphateAdenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]9067317
C560978aegeline[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA28843594
D016604Aflatoxin B1Aflatoxin B1 affects the expression of ABCC2 protein20106945
D016604Aflatoxin B1[Aflatoxin B1 co-treated with finrozole] results in decreased expression of ABCC2 protein23402939
D016604Aflatoxin B1[Aflatoxin B1 co-treated with finrozole] results in increased expression of ABCC2 protein23402939
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ABCC2 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of ABCC2 mRNA23402939
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of ABCC2 protein23402939
D016604Aflatoxin B1finrozole inhibits the reaction [Aflatoxin B1 results in increased expression of ABCC2 mRNA]23402939
C412373AG 1879"AG 1879 inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]"25813982
C412373AG 1879AG 1879 inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]25813982
C031143AICA ribonucleotideAICA ribonucleotide results in decreased expression of ABCC2 mRNA27090119
C008088alfacalcidolalfacalcidol results in increased expression of ABCC2 mRNA19581390
C526957alisol B 23-acetatealisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]25655198
C526957alisol B 23-acetatealisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]25655198
C526957alisol B 23-acetate"pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]"25655198
D000477Alkylating AgentsABCC2 protein results in decreased activity of Alkylating Agents14569069
C006463allyl alcoholallyl alcohol results in increased expression of ABCC2 protein19371622
C038491allyl sulfideallyl sulfide results in increased expression of ABCC2 protein12920174
C010845aluminum chloridealuminum chloride results in increased expression of ABCC2 protein16084594
D000536Aluminum HydroxideAluminum Hydroxide results in decreased expression of ABCC2 protein14976346
D009762o-AminoazotolueneNR1I3 gene mutant form inhibits the reaction [o-Aminoazotoluene results in increased expression of ABCC2 mRNA]21672546
D009762o-Aminoazotolueneo-Aminoazotoluene results in increased expression of ABCC2 mRNA21672546
D000638AmiodaroneAmiodarone affects the expression of ABCC2 mRNA25064622
D000638AmiodaroneAmiodarone results in increased expression of ABCC2 mRNA27765674
C010680antibiotic G 418ABCC2 protein results in increased transport of antibiotic G 41820018165
D000927AnticonvulsantsABCC2 protein results in decreased susceptibility to Anticonvulsants15581025
D000927AnticonvulsantsABCC2 protein affects the transport of Anticonvulsants14636316
D000966Antimony Potassium TartrateAntimony Potassium Tartrate results in increased expression of ABCC2 mRNA11408547
D000966Antimony Potassium TartrateAntimony Potassium Tartrate results in increased expression of ABCC2 protein11408547
C526219apple polyphenol extractapple polyphenol extract results in increased expression of ABCC2 mRNA18351577
D001151ArsenicArsenic results in increased expression of ABCC218020683
D001151ArsenicABCC2 protein results in increased transport of Arsenic25752797
D001151ArsenicArsenic results in increased expression of ABCC2 protein25752797
D001151ArsenicABCC2 protein results in increased transport of Arsenic25752797
C006632arsenic trioxideABCC2 protein results in decreased susceptibility to arsenic trioxide21783896
C006632arsenic trioxidearsenic trioxide results in decreased expression of ABCC2 mRNA22214486
C006632arsenic trioxidearsenic trioxide results in decreased expression of ABCC2 protein21945491
C006632arsenic trioxidearsenic trioxide results in increased expression of ABCC2 mRNA21945491|2773672
C006632arsenic trioxidearsenic trioxide results in increased expression of ABCC2 protein27736728
C006632arsenic trioxidearsenic trioxide results in increased expression of ABCC2 mRNA22580103
C015001arsenitearsenite results in increased expression of ABCC2 mRNA11836020
C015001arsenitearsenite results in increased expression of ABCC2 protein11836020
C015001arseniteABCC2 protein results in increased transport of arsenite17467962
C015001arseniteABCC2 protein results in increased transport of arsenite17467962
D001205Ascorbic Acid"Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]"22914566
D001205Ascorbic Acid"Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]"19326901
D001205Ascorbic Acid"Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"19326901
D000069059Atorvastatin CalciumABCC2 protein binds to and results in increased uptake of Atorvastatin Calcium analog23562342
D000069059Atorvastatin Calcium"Atorvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D000069059Atorvastatin CalciumAtorvastatin Calcium analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D000069059Atorvastatin CalciumAtorvastatin Calcium analog results in decreased activity of ABCC2 protein15616150
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased expression of ABCC2 mRNA25278499
D000069059Atorvastatin CalciumABCC2 protein binds to and results in increased uptake of Atorvastatin Calcium analog23562342
D000069059Atorvastatin Calcium"Atorvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D000069059Atorvastatin CalciumAtorvastatin Calcium analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D000069059Atorvastatin CalciumAtorvastatin Calcium analog results in decreased activity of ABCC2 protein15616150
D001379AzathioprineAzathioprine results in increased expression of ABCC2 mRNA22623647
D001379AzathioprineAzathioprine results in increased expression of ABCC2 mRNA27765674
D001398AztreonamAztreonam results in increased expression of ABCC2 mRNA24657338
C038044baicalinABCC2 protein affects the export of baicalin15587936
D001553BenzbromaroneBenzbromarone results in decreased activity of ABCC2 protein22646477
D001553Benzbromarone"[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
D001553Benzbromarone[Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium19853032
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of ABCC2 mRNA16426233|1973760
D019324beta-Naphthoflavone[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC2 mRNA15833929
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of ABCC2 mRNA15833929|1642623
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of ABCC2 mRNA23064032
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased expression of ABCC2 mRNA20607812
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of ABCC2 mRNA11752103
C009999benzonidazolebenzonidazole results in increased expression of ABCC2 mRNA27180241
C009999benzonidazolebenzonidazole results in increased expression of ABCC2 protein27180241
C009999benzonidazoleNFE2L2 protein affects the reaction [benzonidazole results in increased expression of ABCC2 protein]27180241
C009999benzonidazolebenzonidazole results in increased expression of ABCC2 mRNA27180241
C009999benzonidazoleNFE2L2 protein affects the reaction [benzonidazole results in increased expression of ABCC2 mRNA]27180241
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ABCC2 mRNA21632981|2231617
D001564Benzo(a)pyreneABCC2 protein results in increased transport of Benzo(a)pyrene25451572
D001564Benzo(a)pyreneABCC2 protein results in increased transport of Benzo(a)pyrene metabolite25451572
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ABCC2 mRNA19770486|2171566
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ABCC2 mRNA22227637
C047307benzoylaconine[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylaconine23200901
C479202benzoylhypaconine[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylhypaconine23200901
C085283benzoylmesaconine[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylmesaconine23200901
D004958EstradiolABCC2 protein affects the transport of Estradiol15507541
D004958EstradiolEstradiol results in increased expression of ABCC2 mRNA19580841
D004958EstradiolEstradiol results in increased expression of ABCC2 protein19580841
D004958EstradiolABCC2 protein affects the transport of Estradiol15507541
D004958EstradiolEstradiol affects the localization of and affects the activity of ABCC2 protein15374814
C023888beta-hexachlorocyclohexanebeta-hexachlorocyclohexane results in increased expression of ABCC2 mRNA28392238
D001629BezafibrateBezafibrate affects the localization of ABCC2 protein15258199
D001629BezafibrateBezafibrate results in increased expression of ABCC2 mRNA15258199
D001629BezafibrateBezafibrate results in increased expression of ABCC2 mRNA21549692
D001647Bile Acids and SaltsABCC2 protein affects the transport of Bile Acids and Salts12663868
D001647Bile Acids and SaltsBile Acids and Salts promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12704183
D001647Bile Acids and Saltsestradiol-17 beta-glucuronide promotes the reaction [ABCC2 protein affects the transport of Bile Acids and Salts]12704183
D001647Bile Acids and SaltsTAK-875 affects the reaction [ABCC2 protein results in increased transport of Bile Acids and Salts]28108665
D001647Bile Acids and SaltsTAK-875 inhibits the reaction [ABCC2 protein results in increased transport of Bile Acids and Salts]28108665
D001647Bile Acids and SaltsBile Acids and Salts analog results in increased expression of ABCC2 mRNA11897625
D001663BilirubinABCC2 protein affects the transport of Bilirubin15374814
D001663BilirubinBilirubin analog inhibits the reaction [tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein]24306262
D001663BilirubinBilirubin results in decreased activity of ABCC2 protein15901347
D001663BilirubinABCC2 protein affects the transport of Bilirubin15965653
C016266bilirubin glucuronateABCC2 protein affects the transport of bilirubin glucuronate16611851
C016266bilirubin glucuronatebilirubin glucuronate results in increased expression of ABCC2 mRNA11897625
C004541biochanin Abiochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C452139BIRB 796BIRB 796 results in increased expression of ABCC2 mRNA21328587
C034786bis(4-hydroxycinnamoyl)methanebis(4-hydroxycinnamoyl)methane results in decreased activity of ABCC2 protein15885658
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Cadmium Chloride results in decreased activity of ABCC2 protein]11961059
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Mercuric Chloride results in decreased activity of ABCC2 protein]11961059
C006780bisphenol Abisphenol A results in increased expression of ABCC2 mRNA18634814
C006780bisphenol Abisphenol A results in increased expression of ABCC2 protein18634814
C006780bisphenol Abisphenol A affects the expression of ABCC2 mRNA21786754
C006780bisphenol AABCC2 protein affects the export of bisphenol A analog15466492
C006780bisphenol Abisphenol A affects the methylation of ABCC2 promoter27415467
C006780bisphenol Abisphenol A results in decreased expression of ABCC2 mRNA25181051
C512161bisphenol A glucuronidebisphenol A glucuronide binds to ABCC2 protein22552776
C504983BMS 536924BMS 536924 results in decreased expression of ABCC2 protein26394120
C011686boldineboldine results in increased expression of ABCC2 mRNA25771127
D000069286BortezomibBortezomib results in increased expression of ABCC2 mRNA21215737
C086232bosentanbosentan results in decreased expression of ABCC2 mRNA28369585
C086232bosentanbosentan results in increased expression of ABCC2 mRNA27765674
C053083bromfenacbromfenac results in decreased activity of ABCC2 protein22646477
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D002065BuspironeBuspirone results in decreased expression of ABCC2 mRNA24136188
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of ABCC2 mRNA16426233
D002083Butylated Hydroxyanisole[Butylated Hydroxyanisole results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA15833929
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of ABCC2 mRNA15833929|1642623
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of ABCC2 protein16426233
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of ABCC2 mRNA22956110
D020122tert-ButylhydroperoxideBilirubin analog inhibits the reaction [tert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein]24306262
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide affects the localization of and results in decreased activity of ABCC2 protein24306262
C018475butyraldehydebutyraldehyde results in decreased expression of ABCC2 mRNA26079696
D002101Cacodylic AcidCacodylic Acid results in increased expression of ABCC2 mRNA16436460
D002101Cacodylic AcidCacodylic Acid results in increased expression of ABCC2 protein16436460
D002104CadmiumABCC2 protein results in increased secretion of Cadmium21266201
C028031cadmium acetatecadmium acetate affects the expression of ABCC2 mRNA16249259
D019256Cadmium Chloridebisindolylmaleimide I inhibits the reaction [Cadmium Chloride results in decreased activity of ABCC2 protein]11961059
D019256Cadmium ChlorideCadmium Chloride results in decreased activity of ABCC2 protein11961059
D019256Cadmium ChlorideNifedipine inhibits the reaction [Cadmium Chloride results in decreased activity of ABCC2 protein]11961059
D019256Cadmium ChlorideRES 701-1 inhibits the reaction [Cadmium Chloride results in decreased activity of ABCC2 protein]11961059
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ABCC222914987
D019256Cadmium Chloride[MT1 gene mutant form co-treated with MT2 gene mutant form] inhibits the reaction [Cadmium Chloride results in increased expression of ABCC2]22914987
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ABCC2 mRNA22580103
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ABCC2 mRNA25993096
D019256Cadmium ChlorideCadmium Chloride results in decreased methylation of ABCC2 promoter22457795
D002110Caffeine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA28843594
C085925calcein AMABCC2 protein results in decreased abundance of calcein AM21266201
C085925calcein AMverlukast inhibits the reaction [ABCC2 protein results in decreased abundance of calcein AM]21266201
C085925calcein AMABCC2 protein affects the transport of calcein AM15210835
C085925calcein AMABCC2 protein results in increased export of calcein AM19952419
C085925calcein AMABCC2 protein results in increased transport of calcein AM15616150|1964705
C085925calcein AMAtorvastatin Calcium analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
C085925calcein AMLovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
C085925calcein AMmontelukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]19952419
C085925calcein AM[MYC protein results in increased expression of ABCC2 protein] which results in increased export of calcein AM19239227
C085925calcein AMSimvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
C085925calcein AMverlukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]19952419
C085925calcein AMverlukast inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]19647055
C085925calcein AMzearalenol inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]19647055
C085925calcein AMZearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]19647055
C085925calcein AMABCC2 protein results in increased transport of calcein AM15616150
C085925calcein AMAtorvastatin Calcium analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
C085925calcein AMLovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
C085925calcein AMSimvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D002118Calcium"Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"25862123
D002220CarbamazepineCarbamazepine affects the expression of ABCC2 mRNA23774253
D002220CarbamazepineABCC2 gene SNP affects the susceptibility to Carbamazepine20216337
D002220CarbamazepineABCC2 protein results in increased transport of Carbamazepine20216337
D002220CarbamazepineCarbamazepine results in increased expression of ABCC2 mRNA15371980|1711280
D002220CarbamazepineCarbamazepine results in increased expression of ABCC2 protein15371980
D002220CarbamazepineCarbamazepine results in decreased expression of ABCC2 mRNA19632730
D002220CarbamazepineKN 62 inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]18473823
D002220CarbamazepineTetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]18473823
D002248Carbon MonoxideCarbon Monoxide results in increased activity of ABCC2 protein13678533
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ABCC2 mRNA15496496
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ABCC2 protein16177239
D002251Carbon Tetrachloride[Carbon Tetrachloride co-treated with Valproic Acid] affects the expression of ABCC2 mRNA17617793
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased activity of ABCC2 protein16899240
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of ABCC2 protein12642476|1689924
D002330CarmustineABCC2 mRNA affects the susceptibility to Carmustine16365179
D012844SincalideABCC2 protein affects the export of Sincalide15665139|1604666
D000068579CelecoxibCelecoxib results in decreased activity of ABCC2 protein22646477
D002509CephaloridineCephaloridine results in increased expression of ABCC2 mRNA18500788
D002512Cephalothin[Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA24657338
C086276cerivastatinABCC2 protein affects the export of cerivastatin15901800
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of ABCC2 mRNA25055961
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of ABCC2 mRNA25582706
D002635Chenodeoxycholic AcidABCC2 protein affects the reaction [verlukast results in decreased secretion of Chenodeoxycholic Acid]21262925
D002635Chenodeoxycholic AcidChenodeoxycholic Acid affects the expression of ABCC2 mRNA20888898
D002635Chenodeoxycholic AcidChenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D002635Chenodeoxycholic AcidN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]27743861
D002699ChlorambucilABCC2 protein affects the export of Chlorambucil analog14569069
D002699ChlorambucilABCC2 protein promotes the reaction [GSTA1 protein results in decreased susceptibility to Chlorambucil]14569069
D002706ChlordanChlordan results in decreased activity of ABCC2 protein24464585
D002706ChlordanChlordan results in increased expression of ABCC2 mRNA24464585
D007631ChlordeconeChlordecone results in decreased activity of ABCC2 protein24464585
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of ABCC2 mRNA22659317
D002726Chlorogenic AcidChlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein]25043994
D002738ChloroquineChloroquine results in decreased expression of ABCC2 mRNA27692344
D002738ChloroquineChloroquine results in decreased expression of ABCC2 protein27692344
D002746ChlorpromazineChlorpromazine affects the expression of ABCC2 mRNA25064622
D002746ChlorpromazineChlorpromazine results in increased expression of ABCC2 mRNA27765674
D019826Cholic AcidCholic Acid results in increased expression of ABCC2 mRNA25055961
D019826Cholic AcidCholic Acid results in increased expression of ABCC2 mRNA11438506|1297195
D019826Cholic AcidCholic Acid results in increased expression of ABCC2 protein11438506
D002794Choline[LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA24384915
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA24384915
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA24384915
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 protein17640958|2438491
C043561chrysinchrysin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C043561chrysinchrysin results in decreased activity of ABCC2 protein20457140
C043561chrysin[chrysin results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan20457140
C043561chrysinchrysin results in increased expression of ABCC2 protein20457140
C027113chrysophanic acidchrysophanic acid results in increased expression of ABCC2 mRNA28161596
C027113chrysophanic acidchrysophanic acid results in increased expression of ABCC2 protein28161596
D002939CiprofloxacinCiprofloxacin results in decreased expression of ABCC2 mRNA24657338
D015283CitalopramCitalopram results in increased expression of ABCC2 protein12524417
C118029CL 387785CL 387785 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]25813982
C012255clobazamABCC2 protein affects the susceptibility to clobazam22982618
D002994ClofibrateClofibrate results in increased expression of ABCC2 mRNA22496397|2897355
D002994ClofibrateClofibrate results in decreased expression of ABCC2 mRNA11328961|1922454
D002995Clofibric AcidClofibric Acid results in increased expression of ABCC2 mRNA22559005
D002995Clofibric AcidClofibric Acid results in decreased expression of ABCC2 protein15908472
D003022ClotrimazoleClotrimazole results in increased expression of ABCC2 mRNA11836020
D003022ClotrimazoleClotrimazole results in increased expression of ABCC2 protein11836020
C004690coclaurine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA28843594
D005576ColforsinColforsin results in increased expression of ABCC2 mRNA19580841
D005576ColforsinColforsin results in increased expression of ABCC2 protein26049102
C075384coniferaldehydeconiferaldehyde results in increased expression of ABCC2 mRNA26275128
D003300Copper[Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA25167922
D019327Copper SulfateCopper Sulfate results in increased expression of ABCC2 mRNA19549813
D003474CurcuminCurcumin results in decreased activity of ABCC2 protein15885658
C057862cyanoginosin LRcyanoginosin LR results in increased expression of ABCC2 mRNA17654400
D016572CyclosporineCyclosporine affects the expression of ABCC2 mRNA25064622
D016572CyclosporineCyclosporine affects the expression of ABCC2 mRNA24973091
D016572Cyclosporine"Cyclosporine inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]"24973091
D016572CyclosporineCyclosporine results in decreased activity of ABCC2 protein15618715|1631693
D016572Cyclosporine"[Cyclosporine results in decreased activity of ABCC2 protein] which affects the transport of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16356829
D016572Cyclosporine[Cyclosporine results in decreased activity of ABCC2 protein] which results in increased abundance of Lithocholic Acid26198044
D016572CyclosporineCyclosporine results in decreased expression of ABCC2 mRNA20106945
D016572CyclosporineCyclosporine results in increased expression of ABCC2 mRNA25562108
D016572CyclosporineCyclosporine inhibits the reaction [ABCC2 protein affects the transport of mycophenolic acid glucuronide]15816878
D016572CyclosporineCyclosporine inhibits the reaction [ABCC2 protein results in increased secretion of Fluo-3]9794919
D016572CyclosporineCyclosporine results in decreased activity of ABCC2 protein15618715
D016572CyclosporineCyclosporine results in decreased expression of ABCC2 mRNA11589784
D016572CyclosporineCyclosporine results in increased expression of ABCC2 mRNA21865292|2776567
D016572CyclosporineCyclosporine results in decreased activity of ABCC2 protein16356829
C093628cyproconazolecyproconazole results in increased expression of ABCC2 mRNA28058446
C093628cyproconazole[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA29038839
D003545CysteineABCC2 protein affects the transport of [Mercury co-treated with Cysteine]21134393
D003545CysteineABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]18511429
D003545CysteineABCC2 protein affects the reaction [Unithiol binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]18511429
D003545CysteineABCC2 protein binds to and results in increased secretion of [Succimer binds to [Mercuric Chloride binds to Cysteine]]18511429
D003545CysteineABCC2 protein binds to and results in increased secretion of [Unithiol binds to [Mercuric Chloride binds to Cysteine]]18511429
D003609DactinomycinDactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]26049102
D003609DactinomycinABCC2 protein results in decreased susceptibility to Dactinomycin11455017
D003609DactinomycinDactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]11408547
D003622DapsoneDapsone metabolite results in decreased expression of ABCC2 protein15863252
D003630Daunorubicin[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin29079042
D003630DaunorubicinABCC2 affects the susceptibility to Daunorubicin18451141
D003630DaunorubicinIndomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin]29079042
D003630DaunorubicinIndomethacin inhibits the reaction [[Methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin]29079042
D003630Daunorubicin[Methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin29079042
D003634DDTDDT results in increased expression of ABCC2 mRNA24464585
C014347decitabinedecitabine results in increased expression of ABCC2 mRNA11509559
C050229demethoxycurcumindemethoxycurcumin results in decreased activity of ABCC2 protein15885658
D003840Deoxycholic AcidDeoxycholic Acid affects the expression of ABCC2 mRNA21914718
D003840Deoxycholic AcidSLCO1A1 protein affects the susceptibility to [Deoxycholic Acid affects the expression of ABCC2 mRNA]21914718
C121345desloratadinedesloratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]22095822
D003907DexamethasoneDexamethasone results in increased expression of ABCC2 mRNA20888898
D003907DexamethasoneDexamethasone results in decreased expression of ABCC2 mRNA15102944|1992276
D003907DexamethasoneDexamethasone results in increased expression of ABCC2 mRNA12429353|1911856
D003907DexamethasoneDexamethasone results in increased expression of ABCC2 protein15258109|1590847
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in increased expression of ABCC2 mRNA]20032058
D016264Dextran SulfateDextran Sulfate results in decreased expression of ABCC2 mRNA27580383
D016264Dextran SulfateDextran Sulfate results in decreased expression of ABCC2 protein27580383
D016190CarboplatinCarboplatin results in decreased expression of ABCC2 mRNA27692344
D016190CarboplatinCarboplatin results in decreased expression of ABCC2 protein27692344
D003994BucladesineBucladesine promotes the reaction [ATF2 protein binds to ABCC2 promoter]26049102
D003994BucladesineBucladesine promotes the reaction [JUN protein binds to ABCC2 promoter]26049102
D003994BucladesineBucladesine results in increased activity of ABCC2 protein29052767
D003994BucladesineBucladesine results in increased activity of and affects the localization of ABCC2 protein29052767
D003994BucladesineBucladesine results in increased expression of ABCC2 mRNA26049102
D003994BucladesineBucladesine results in increased expression of ABCC2 protein26049102
D003994BucladesineDactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]26049102
D003994BucladesineKT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]29052767
D003994BucladesineKT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]26049102
D003994BucladesineKT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]26049102
D003994BucladesineN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]26049102
D003994Bucladesineverlukast inhibits the reaction [Bucladesine results in increased activity of ABCC2 protein]29052767
D003994BucladesineBucladesine affects the localization of ABCC2 protein29052767
D003994BucladesineBucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]12029626
D003994BucladesineKT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]29052767
D002945CisplatinABCC2 affects the susceptibility to Cisplatin15756446
D002945CisplatinABCC2 protein affects the export of Cisplatin15985617
D002945CisplatinABCC2 protein inhibits the reaction [ABCC2 gene mutant form results in increased susceptibility to Cisplatin]24641901|2464190
D002945CisplatinABCC2 protein results in decreased susceptibility to Cisplatin15688364|1798267
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of ABCC2 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of ABCC221905038
D002945CisplatinCisplatin results in decreased expression of ABCC2 mRNA20737486
D002945CisplatinCisplatin results in increased expression of ABCC2 mRNA27392435
D002945CisplatinCisplatin results in increased expression of ABCC2 protein26721606
D002945Cisplatin[Proadifen co-treated with Cisplatin] results in increased expression of ABCC2 protein26721606
D002945Cisplatin[PTGS2 protein results in increased expression of ABCC2 protein] which results in increased susceptibility to Cisplatin18695918
D002945CisplatinABCC2 gene mutant form results in increased susceptibility to Cisplatin24641901
D002945CisplatinChlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein]25043994
D002945CisplatinCisplatin results in increased expression of ABCC2 mRNA20605904
D002945CisplatinCisplatin results in increased expression of ABCC2 protein20605904|2377041
D002945Cisplatin[Luteolin co-treated with Cisplatin] results in increased expression of ABCC2 protein23770416
D002945CisplatinLuteolin inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein]23770416
D002945CisplatinNFE2L2 protein promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]20605904
D002945CisplatinNFE2L2 protein promotes the reaction [Cisplatin results in increased expression of ABCC2 protein]20605904
D002945CisplatinABCC2 protein results in decreased susceptibility to Cisplatin11455017
D002945CisplatinCisplatin results in decreased expression of ABCC2 mRNA26739623
D002945CisplatinCisplatin results in increased expression of ABCC2 mRNA22023808|2299243
D002945CisplatinCisplatin results in increased expression of ABCC2 protein22992436
D002945Cisplatinformononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]28414026
D002945CisplatinJBP 485 promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]22992436
D002945CisplatinJBP 485 promotes the reaction [Cisplatin results in increased expression of ABCC2 protein]22992436
D002945CisplatinLovastatin promotes the reaction [Cisplatin results in decreased expression of ABCC2 mRNA]26739623
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased expression of ABCC2 mRNA28392238
D004000DichloroethylenesDichloroethylenes results in decreased expression of ABCC2 protein15554242
D004008DiclofenacDiclofenac results in decreased activity of ABCC2 protein22646477
D004008DiclofenacDiclofenac results in increased expression of ABCC2 mRNA19022234
D004008DiclofenacABCC2 protein results in increased transport of and results in increased metabolism of and results in increased susceptibility to Diclofenac25450747
C000944dicrotophosdicrotophos results in increased expression of ABCC2 mRNA28302478
D016048Dideoxyadenosine"Dideoxyadenosine inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]"25813982
D004026DieldrinDieldrin results in increased expression of ABCC2 mRNA24464585
D004041Dietary Fats[Dietary Fats co-treated with sodium arsenite] results in increased expression of ABCC2 mRNA26890134
D004041Dietary FatsDietary Fats results in decreased expression of ABCC222521610
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of ABCC2 mRNA11752103
C014476diethyl maleatediethyl maleate results in increased expression of ABCC2 mRNA25270620
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA18544905
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA18544905
D004052Diethylnitrosamine[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA23665939
D002117CalcitriolCalcitriol results in increased expression of ABCC2 mRNA27107558
D002117CalcitriolCalcitriol results in increased activity of ABCC2 protein21240898|2134128
D002117CalcitriolCalcitriol results in increased expression of ABCC2 protein21240898|2134128
D004137DinitrochlorobenzeneABCC2 protein results in decreased susceptibility to Dinitrochlorobenzene26049102
C019357dioscindioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]27317372
C019357dioscindioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]27317372
D004144DiosgeninDiosgenin results in increased expression of ABCC2 mRNA16105132
D004144Diosgenin[Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of ABCC2 mRNA16105132
C067311docetaxelABCC2 protein affects the transport of docetaxel15849751
C067311docetaxel[docetaxel results in decreased susceptibility to docetaxel] which results in decreased expression of ABCC2 mRNA19944135
C067311docetaxelProbenecid promotes the reaction [ABCC2 protein affects the transport of docetaxel]15849751
D004308DothiepinDothiepin results in increased expression of ABCC2 protein12524417
D004317DoxorubicinABCC2 protein affects the transport of Doxorubicin16611851
D004317DoxorubicinABCC2 protein results in decreased susceptibility to Doxorubicin11455017
D004365Drugs, Chinese Herbal"[Drugs, Chinese Herbal results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA"16267138
C095803E 3040[SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of E 3040 analog19628752
C095803E 3040ABCC2 protein affects the export of E 3040 analog15598971
D004642EmodinEmodin results in decreased expression of ABCC2 mRNA28161596
D004642EmodinEmodin results in decreased expression of ABCC2 protein28161596
D004642EmodinEmodin results in increased expression of ABCC2 mRNA19549930
D004726EndosulfanEndosulfan results in decreased activity of ABCC2 protein24464585
D004731EndotoxinsEndotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA]15456840
C040240enkephalin-Leu, Ala(2)-melphalan methyl ester-"ABCC2 protein affects the transport of enkephalin-Leu, Ala(2)-melphalan methyl ester- analog"12134948|1213494
D015251Epirubicin"3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]"22914566
D015251EpirubicinEpirubicin analog results in increased expression of ABCC2 mRNA26335193
D015251EpirubicinEpirubicin results in increased expression of ABCC2 mRNA22914566|2386790
D015251Epirubicinformononetin inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]23867903
C045651epigallocatechin gallateepigallocatechin gallate results in decreased expression of ABCC2 protein23146761
C109476epoxiconazole[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA29038839
C109476epoxiconazoleepoxiconazole results in increased expression of ABCC2 mRNA29038839
C073539erucin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mRNA]15896333
C073539erucin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [erucin results in increased expression of ABCC2 mRNA]15896333
C073539erucinerucin results in increased expression of ABCC2 mRNA15896333
C025483estradiol-17 beta-glucuronideABCC2 protein affects the export of estradiol-17 beta-glucuronide15652233|1590180
C025483estradiol-17 beta-glucuronideABCC2 protein affects the transport of estradiol-17 beta-glucuronide11500505|1270271
C025483estradiol-17 beta-glucuronideBile Acids and Salts promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide promotes the reaction [ABCC2 protein affects the transport of Bile Acids and Salts]12704183
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide results in decreased activity of and affects the localization of ABCC2 protein29052767
C025483estradiol-17 beta-glucuronideEthinyl Estradiol metabolite promotes the reaction [ABCC2 protein results in increased uptake of estradiol-17 beta-glucuronide]14722317
C025483estradiol-17 beta-glucuronideFurosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronideGo 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]29052767
C025483estradiol-17 beta-glucuronideIndomethacin promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717|1270418
C025483estradiol-17 beta-glucuronidepantoprazole promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717
C025483estradiol-17 beta-glucuronidePenicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717
C025483estradiol-17 beta-glucuronideProbenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12704183
C025483estradiol-17 beta-glucuronide[SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of estradiol-17 beta-glucuronide19628752
C025483estradiol-17 beta-glucuronide[SLCO1B1 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide18180276
C025483estradiol-17 beta-glucuronide[SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide18180276
C025483estradiol-17 beta-glucuronidesulfanitran promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717
C025483estradiol-17 beta-glucuronideABCC2 protein affects the transport of estradiol-17 beta-glucuronide9614209
C025483estradiol-17 beta-glucuronidefluorescein-methotrexate inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C025483estradiol-17 beta-glucuronideLeukotriene C4 inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C025483estradiol-17 beta-glucuronidephenolphthalein glucuronide inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C025483estradiol-17 beta-glucuronideverlukast inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C025483estradiol-17 beta-glucuronideABCC2 protein affects the susceptibility to estradiol-17 beta-glucuronide12702498
C025483estradiol-17 beta-glucuronideABCC2 protein affects the transport of estradiol-17 beta-glucuronide12642476|1590467
C025483estradiol-17 beta-glucuronideABCC2 protein modified form results in increased transport of estradiol-17 beta-glucuronide15904671
C025483estradiol-17 beta-glucuronideABCC2 protein results in increased transport of estradiol-17 beta-glucuronide18436619
C025483estradiol-17 beta-glucuronideabietic acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]18436619
C025483estradiol-17 beta-glucuronideAG 1879 inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]25813982
C025483estradiol-17 beta-glucuronideBucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]12029626
C025483estradiol-17 beta-glucuronideCL 387785 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]25813982
C025483estradiol-17 beta-glucuronideEGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]]25813982
C025483estradiol-17 beta-glucuronideEGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]25813982
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide affects the localization of ABCC2 protein12029626|1289383
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein25813982
C025483estradiol-17 beta-glucuronideestradiol-17 beta-glucuronide results in decreased secretion of ABCC2 protein29090346
C025483estradiol-17 beta-glucuronidefulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]25813982
C025483estradiol-17 beta-glucuronideGlycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]18436619
C025483estradiol-17 beta-glucuronideGo 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]18972403|2081501
C025483estradiol-17 beta-glucuronideIGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]29090346
C025483estradiol-17 beta-glucuronideProtein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]25813982
C025483estradiol-17 beta-glucuronidetyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]29090346
C025483estradiol-17 beta-glucuronidetyrphostin AG 1478 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]25813982
C025483estradiol-17 beta-glucuronidewortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]20815017
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased methylation of ABCC2 promoter27415467
C017296estrone sulfateABCC2 protein affects the export of estrone sulfate15652233|1604666
C017296estrone sulfateestrone sulfate results in increased activity of ABCC2 protein15904671
C017296estrone sulfateestrone sulfate results in increased activity of ABCC2 protein modified form15904671
D004976Ethacrynic AcidABCC2 protein results in increased transport of Ethacrynic Acid16316932
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of ABCC2 mRNA25064622
D004997Ethinyl EstradiolABCC2 protein results in increased uptake of Ethinyl Estradiol metabolite14722317
D004997Ethinyl EstradiolEthinyl Estradiol metabolite promotes the reaction [ABCC2 protein results in increased uptake of estradiol-17 beta-glucuronide]14722317
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ABCC2 mRNA27743861
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of and results in increased activity of ABCC2 protein24685904
D004997Ethinyl Estradiolfulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCC2 protein]24685904
D004997Ethinyl EstradiolPRKACA protein affects the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D004997Ethinyl EstradiolPRKACB protein affects the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ABCC2 mRNA27818225
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ABCC2 protein27818225
D004997Ethinyl EstradiolSRT1720 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27818225
D004997Ethinyl EstradiolSRT1720 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]27818225
D004997Ethinyl Estradiol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]"27090119
D004997Ethinyl Estradiol"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]"27090119
D004997Ethinyl Estradiol8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D004997Ethinyl EstradiolChenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D004997Ethinyl EstradiolEthinyl Estradiol affects the localization of ABCC2 protein17681005
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of ABCC2 mRNA16105132
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Spironolactone] results in increased expression of ABCC2 protein17686906
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ABCC2 mRNA27090119|2774386
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ABCC2 protein16554369|1768690
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of and results in decreased localization of and results in decreased activity of ABCC2 protein15843489
D004997Ethinyl EstradiolGW 4064 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]27090119
D004997Ethinyl EstradiolN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]27743861
D004997Ethinyl EstradiolN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]27743861
D004997Ethinyl EstradiolNR1H4 protein inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27090119
D004997Ethinyl EstradiolPRKAA1 protein inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27090119
D004997Ethinyl EstradiolUrsodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased activity of ABCC2 protein]15843489
D004997Ethinyl EstradiolUrsodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D005015Ethoxyquin[Ethoxyquin results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA15833929
D005015EthoxyquinEthoxyquin results in increased expression of ABCC2 mRNA15833929
C026098etiracetametiracetam results in increased expression of ABCC2 protein18473823
D005047EtoposideABCC2 protein affects the transport of Etoposide15751272|1584975
D005047EtoposideProbenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]15849751
D015025ZearalenoneABCC2 protein results in increased transport of Zearalenone19647055
D015025Zearalenoneverlukast inhibits the reaction [ABCC2 protein results in increased transport of Zearalenone]19647055
D015025ZearalenoneZearalenone inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]19647055
D015025ZearalenoneZearalenone results in increased expression of ABCC2 mRNA19580841
D011345FenofibrateFenofibrate results in increased expression of ABCC2 mRNA27765674
C020326ferric nitrilotriacetateferric nitrilotriacetate results in increased expression of ABCC2 mRNA18617210
C093230fexofenadine[SLCO1B1 protein co-treated with ABCC2 protein] results in increased uptake of fexofenadine18180276
C093230fexofenadine[SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of fexofenadine18180276
C093230fexofenadineABCC2 protein results in increased export of fexofenadine18245269
C111409finrozole[Aflatoxin B1 co-treated with finrozole] results in decreased expression of ABCC2 protein23402939
C111409finrozole[Aflatoxin B1 co-treated with finrozole] results in increased expression of ABCC2 protein23402939
C111409finrozolefinrozole inhibits the reaction [Aflatoxin B1 results in increased expression of ABCC2 mRNA]23402939
C111409finrozolefinrozole results in increased expression of ABCC2 protein23402939
C082360fipronilfipronil results in increased expression of ABCC2 mRNA23962444
C082360fipronilfipronil results in increased expression of ABCC2 mRNA23962444
C059715Fluo-3ABCC2 protein results in increased secretion of Fluo-39794919
C059715Fluo-3Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased secretion of Fluo-3]9794919
C059715Fluo-3Cyclosporine inhibits the reaction [ABCC2 protein results in increased secretion of Fluo-3]9794919
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of ABCC2 mRNA10691972|1642623
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of ABCC2 protein10691972
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of ABCC2 mRNA16381673|1642623
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of ABCC2 mRNA]16381673
C103864fluorescein-methotrexatefluorescein-methotrexate inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C007740fluorexonABCC2 protein affects the export of fluorexon15670588
C007740fluorexonABCC2 protein affects the transport of fluorexon15848949
C007740fluorexonABCC2 protein alternative form results in increased abundance of fluorexon22027652
C007740fluorexonrobinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon]15670588
D005472FluorouracilABCC2 protein affects the susceptibility to Fluorouracil16217747
D005485FlutamideFlutamide results in increased expression of ABCC2 mRNA24136188
C065180fluvastatinABCC2 protein binds to and results in increased uptake of fluvastatin analog23562342
C065180fluvastatin"fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C065180fluvastatinABCC2 protein affects the transport of fluvastatin16026004
C065180fluvastatinABCC2 protein binds to and results in increased uptake of fluvastatin analog23562342
C065180fluvastatin"fluvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C065180fluvastatin"fluvastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"24909372
D015378Imipenem[Vancomycin co-treated with Imipenem] affects the expression of ABCC2 mRNA24657338
C007768formononetinAcetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA]23867903
C007768formononetinformononetin inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]23867903
C007768formononetinformononetin results in decreased expression of ABCC2 mRNA23867903
C007768formononetinformononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]28414026
D002955LeucovorinLeucovorin inhibits the reaction [Methotrexate results in decreased expression of ABCC2 protein]16925582
D017328FosinoprilABCC2 protein results in decreased susceptibility to Fosinopril22095822
D017328FosinoprilABCC2 protein results in increased export of Fosinopril22095822
D017328Fosinoprildesloratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]22095822
D017328FosinoprilLoratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]22095822
D017328FosinoprilMethotrexate inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]22095822
D017328FosinoprilABCC2 protein affects the reaction [Fosinopril affects the export of Methotrexate]22095822
C070081fulvestrantfulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of ABCC2 protein]24685904
C070081fulvestrantfulvestrant inhibits the reaction [Genistein results in increased expression of ABCC2 protein]24685904
C070081fulvestrantfulvestrant results in increased expression of ABCC2 protein24685904
C070081fulvestrantEGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]]25813982
C070081fulvestrantfulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]25813982
C039281furanfuran results in increased expression of ABCC2 mRNA25539665
D005665FurosemideFurosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12704183
D005665Furosemide"[Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
D005672Fusidic AcidFusidic Acid results in decreased expression of and results in decreased activity of ABCC2 protein12106615
C094370gemfibrozil 1-O-acylglucuronide[SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of gemfibrozil 1-O-acylglucuronide19628752
D019833Genisteinfulvestrant inhibits the reaction [Genistein results in increased expression of ABCC2 protein]24685904
D019833GenisteinGenistein inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
D019833GenisteinGenistein promotes the reaction [RXRA protein binds to ABCC2 promoter]21689630
D019833GenisteinGenistein results in increased expression of ABCC2 mRNA21689630|2639412
D019833GenisteinGenistein results in increased expression of ABCC2 protein21689630|2639412
D019833GenisteinGenistein results in increased expression of and results in increased activity of ABCC2 protein24685904
D019833Genisteinresveratrol inhibits the reaction [Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]]21689630
D019833Genisteinresveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 mRNA]21689630|2639412
D019833Genisteinresveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 protein]21689630|2639412
D005839GentamicinsGentamicins results in increased expression of ABCC2 mRNA22061828
C063170Ginkgo biloba extractGinkgo biloba extract results in increased expression of ABCC2 mRNA19034627
C477042ginkgolide Aginkgolide A results in increased expression of ABCC2 mRNA19034627
C045856ginkgolide Bginkgolide B results in increased expression of ABCC2 mRNA19034627
C048026ginsenoside Rb2ginsenoside Rb2 results in increased expression of ABCC2 mRNA23835644
C049864ginsenoside ReABCC2 protein results in increased transport of ginsenoside Re25297453
C049864ginsenoside ReABCC2 protein results in increased transport of ginsenoside Re25297453
C035054ginsenoside Rg1ABCC2 protein results in increased transport of ginsenoside Rg125297453
C035054ginsenoside Rg1ABCC2 protein results in increased transport of ginsenoside Rg125297453
C026474ginsenoside Rg2ginsenoside Rg2 results in increased expression of ABCC2 mRNA23835644
D005897GlafenineGlafenine results in decreased expression of ABCC2 mRNA24136188
D005947Glucose"[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
D005947Glucose"[Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
D005947Glucose"[sulfanitran results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
D005978GlutathioneABCC2 protein affects the transport of [5-chloromethylfluorescein co-treated with Glutathione]16049127
D005978GlutathioneABCC2 protein affects the transport of Glutathione analog20584751
D005978GlutathioneGlutathione promotes the reaction [ABCC2 protein affects the export of phenethyl isothiocyanate]16002050
D005978GlutathioneABCC2 protein affects the transport of Glutathione16611851
D005978GlutathioneABCC2 protein affects the abundance of Glutathione25450747
D005978GlutathioneABCC2 protein affects the export of Glutathione15845416
D005978GlutathioneABCC2 protein results in increased transport of [1-Naphthylisothiocyanate binds to Glutathione]21070799
C113118glutathione-BPDE conjugateABCC2 protein affects the export of glutathione-BPDE conjugate22899102
D019803Glutathione DisulfideABCC2 protein results in increased transport of Glutathione Disulfide15276087
D019803Glutathione DisulfideAcetaminophen promotes the reaction [ABCC2 protein results in increased transport of Glutathione Disulfide]15276087
C524061glutathionyl 4-hydroxy-2-nonenal conjugateABCC2 protein results in increased transport of glutathionyl 4-hydroxy-2-nonenal conjugate19326901
C524061glutathionyl 4-hydroxy-2-nonenal conjugateABCC2 protein results in increased transport of glutathionyl 4-hydroxy-2-nonenal conjugate19326901
D005905GlyburideGlyburide results in increased expression of ABCC2 mRNA27765674
D006034Glycyrrhetinic AcidGlycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]18436619
C081021Go 6976Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]29052767
C081021Go 6976Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]18972403|2081501
C412815GW 4064GW 4064 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]27090119
C412815GW 4064GW 4064 results in increased expression of ABCC2 mRNA14623915|1564443
D006533HeptachlorHeptachlor results in decreased activity of ABCC2 protein24464585
D006533HeptachlorHeptachlor results in increased expression of ABCC2 mRNA24464585
D006534Heptachlor EpoxideHeptachlor Epoxide results in increased expression of ABCC2 mRNA25270620
C012348higenamine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA28843594
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of ABCC2 mRNA20044591
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of ABCC222914987
D006861Hydrogen Peroxide[MT1 gene mutant form co-treated with MT2 gene mutant form] inhibits the reaction [Hydrogen Peroxide results in increased expression of ABCC2]22914987
D047348Hydrolyzable Tannins[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA28843594
C058309hypaconitine[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of hypaconitine23200901
D007052IbuprofenIbuprofen results in increased expression of ABCC2 mRNA22559005
C016517indole-3-carbinolindole-3-carbinol results in increased expression of ABCC2 mRNA11752103
D007213IndomethacinIndomethacin inhibits the reaction [5-methoxypsoralen results in decreased activity of ABCC2 protein]29079042
D007213IndomethacinIndomethacin inhibits the reaction [[5-methoxypsoralen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin]29079042
D007213IndomethacinIndomethacin inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate]16636798
D007213IndomethacinIndomethacin inhibits the reaction [Methoxsalen results in decreased activity of ABCC2 protein]29079042
D007213IndomethacinIndomethacin inhibits the reaction [[Methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin]29079042
D007213IndomethacinIndomethacin promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717|1270418
D007213IndomethacinIndomethacin results in decreased activity of ABCC2 protein22646477
D007213IndomethacinIndomethacin results in decreased activity of ABCC2 protein16026004
D007213IndomethacinIndomethacin results in decreased expression of ABCC2 mRNA17329856
D007213IndomethacinIndomethacin results in decreased expression of ABCC2 protein17329856
C030956insecticidal crystal protein, Bacillus Thuringiensis"insecticidal crystal protein, Bacillus Thuringiensis binds to ABCC2 protein"26152191
C051890irinotecanABCC2 gene polymorphism affects the susceptibility to irinotecan18981587
C051890irinotecanABCC2 gene polymorphism affects the susceptibility to irinotecan metabolite18981587
C051890irinotecanABCC2 protein results in decreased susceptibility to irinotecan16815871
C051890irinotecanABCC2 protein results in increased export of irinotecan16271446
C051890irinotecanABCC2 protein results in increased secretion of irinotecan18981587
C051890irinotecanABCC2 protein results in increased secretion of irinotecan metabolite18981587
C000603302isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate"isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein"25844889
C000603302isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate"[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine"25844889
D007559IvermectinIvermectin results in increased expression of ABCC2 mRNA24998875
C412308JBP 485JBP 485 promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]22992436
C412308JBP 485JBP 485 promotes the reaction [Cisplatin results in increased expression of ABCC2 protein]22992436
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of ABCC2 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of ABCC2 mRNA26752646
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of ABCC2 mRNA27432991
C410337K 7174K 7174 results in increased expression of ABCC2 mRNA24086573
D007654KetoconazoleKetoconazole results in decreased activity of ABCC2 protein19070657
D007654KetoconazoleKetoconazole inhibits the reaction [Spironolactone results in increased expression of ABCC2 mRNA]19766108
D007654KetoconazoleABCC2 affects the susceptibility to Ketoconazole18466103
D048628KetolidesKetolides analog results in increased expression of ABCC2 mRNA24967691
C063302KN 62KN 62 inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]18473823
C063302KN 62KN 62 inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]18473823
C063302KN 62KN 62 inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein]18473823
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA18544905
C011890kojic acid[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA18544905
C057416KT 5720KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]29052767
C057416KT 5720KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]26049102
C057416KT 5720KT 5720 inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]26049102
C057416KT 5720KT 5720 inhibits the reaction [Bucladesine affects the localization of ABCC2 protein]29052767
C099406L 742694L 742694 results in decreased expression of ABCC2 mRNA15102944
D007854LeadABCC2 protein results in increased secretion of Lead21266201
D007854LeadLead results in increased expression of ABCC2 mRNA21266201
C118184LE-Cl2MDPLE-Cl2MDP affects the localization of ABCC2 protein15057914
C052901lemongrass oillemongrass oil affects the expression of ABCC2 mRNA25976427
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in decreased expression of ABCC2 mRNA"22942241
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of ABCC2 mRNA"24972896
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of ABCC2 mRNA"11170838|2393914
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of ABCC2 protein"11170838
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of ABCC2 protein15205115
D008070LipopolysaccharidesLipopolysaccharides results in decreased activity of ABCC2 protein14709616
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of ABCC2 mRNA14709616|1531223
D008070LipopolysaccharidesGCG protein inhibits the reaction [Lipopolysaccharides affects the localization of ABCC2 protein]28842383
D008070LipopolysaccharidesGCG protein inhibits the reaction [Lipopolysaccharides results in decreased expression of ABCC2 mRNA]28842383
D008070LipopolysaccharidesGCG protein inhibits the reaction [Lipopolysaccharides results in decreased expression of and results in decreased activity of ABCC2 protein]28842383
D008070LipopolysaccharidesLipopolysaccharides affects the localization of ABCC2 protein28842383
D008070LipopolysaccharidesLipopolysaccharides affects the localization of and results in decreased expression of ABCC2 protein12706339
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of ABCC2 mRNA15205115|1520538
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of and results in decreased activity of ABCC2 protein28842383
D008070Lipopolysaccharides[TNF protein co-treated with IL1B protein co-treated with IFNG protein co-treated with Lipopolysaccharides] results in decreased expression of ABCC2 mRNA20816778
D008095Lithocholic Acid[Cyclosporine results in decreased activity of ABCC2 protein] which results in increased abundance of Lithocholic Acid26198044
D008095Lithocholic Acid[Lithocholic Acid results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA14570758
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC2 mRNA20888898
D008095Lithocholic AcidLithocholic Acid affects the localization of ABCC2 protein16436656
D008095Lithocholic Acid[Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC2 protein18032408
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC2 mRNA20977460|2558270
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC2 protein20977460
D008095Lithocholic AcidNFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC2 mRNA]20977460
D008095Lithocholic AcidNFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC2 protein]20977460
D008095Lithocholic Acid[Lithocholic Acid binds to and results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA21311750
D008095Lithocholic AcidLithocholic Acid results in increased expression of ABCC2 mRNA20888898
D061466LopinavirABCC2 protein alternative form results in increased abundance of Lopinavir22027652
D061466LopinavirABCC2 protein results in increased secretion of Lopinavir22027652
D017336LoratadineLoratadine inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]22095822
D008148LovastatinABCC2 protein binds to and results in increased uptake of Lovastatin analog23562342
D008148Lovastatin"Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D008148LovastatinLovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D008148LovastatinLovastatin analog results in decreased activity of ABCC2 protein15616150
D008148LovastatinABCC2 protein binds to and results in increased uptake of Lovastatin analog23562342
D008148Lovastatin"Lovastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D008148LovastatinLovastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D008148LovastatinLovastatin analog results in decreased activity of ABCC2 protein15616150
D008148LovastatinLovastatin promotes the reaction [Cisplatin results in decreased expression of ABCC2 mRNA]26739623
D008148LovastatinLovastatin results in increased expression of ABCC2 mRNA26739623
D017997Leukotriene C4ABCC2 protein affects the transport of Leukotriene C415507541
D017997Leukotriene C4ABCC2 protein affects the transport of Leukotriene C411500505|1238819
D017997Leukotriene C4verlukast inhibits the reaction [ABCC2 protein results in increased transport of Leukotriene C4]27676153
D017997Leukotriene C4ABCC2 protein affects the transport of Leukotriene C49614209
D017997Leukotriene C4Leukotriene C4 inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
D017997Leukotriene C4ABCC2 protein affects the transport of Leukotriene C415507541|1590467
D017997Leukotriene C4ABCC2 protein modified form results in increased transport of Leukotriene C415904671
D047311Luteolin[Luteolin co-treated with Cisplatin] results in increased expression of ABCC2 protein23770416
D047311LuteolinLuteolin inhibits the reaction [Cisplatin results in increased expression of ABCC2 protein]23770416
C533860macitentanmacitentan results in decreased expression of ABCC2 mRNA28369585
D008376MaprotilineMaprotiline results in decreased expression of ABCC2 mRNA27765674
D008468Meclizine[Meclizine binds to and results in increased activity of NR1I3 protein] which results in increased expression of ABCC2 mRNA15272053
D008610MentholMenthol results in increased expression of ABCC2 mRNA24594507
D008627Mercuric ChlorideABCC2 protein affects the export of and results in decreased susceptibility to Mercuric Chloride15590114
D008627Mercuric ChlorideMercuric Chloride results in increased expression of ABCC2 mRNA15590114
D008627Mercuric ChlorideMercuric Chloride results in increased expression of ABCC2 protein15590114
D008627Mercuric ChlorideMercuric Chloride affects the expression of ABCC2 mRNA20353558
D008627Mercuric Chloridebisindolylmaleimide I inhibits the reaction [Mercuric Chloride results in decreased activity of ABCC2 protein]11961059
D008627Mercuric ChlorideMercuric Chloride results in decreased activity of ABCC2 protein11961059
D008627Mercuric ChlorideNifedipine inhibits the reaction [Mercuric Chloride results in decreased activity of ABCC2 protein]11961059
D008627Mercuric ChlorideRES 701-1 inhibits the reaction [Mercuric Chloride results in decreased activity of ABCC2 protein]11961059
D008627Mercuric ChlorideABCC2 protein results in decreased susceptibility to Mercuric Chloride21783896
D008627Mercuric ChlorideABCC2 gene mutant form affects the susceptibility to Mercuric Chloride25145654
D008627Mercuric ChlorideABCC2 gene mutant form promotes the reaction [Mercuric Chloride results in increased expression of GCLM mRNA]24039982
D008627Mercuric ChlorideMercuric Chloride results in increased expression of ABCC2 mRNA27720909
D008627Mercuric ChlorideMercuric Chloride affects the expression of ABCC2 mRNA17083914
D008627Mercuric ChlorideMercuric Chloride results in increased expression of ABCC2 mRNA22580103
D008627Mercuric ChlorideABCC2 gene mutant form affects the susceptibility to Mercuric Chloride25145654
D008627Mercuric ChlorideABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]18511429
D008627Mercuric ChlorideABCC2 protein affects the reaction [Unithiol binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]18511429
D008627Mercuric ChlorideABCC2 protein binds to and results in increased secretion of [Succimer binds to [Mercuric Chloride binds to Cysteine]]18511429
D008627Mercuric ChlorideABCC2 protein binds to and results in increased secretion of [Unithiol binds to [Mercuric Chloride binds to Cysteine]]18511429
D008627Mercuric ChlorideMercuric Chloride affects the expression of ABCC2 mRNA28536007
D008628MercuryABCC2 protein affects the export of and results in decreased susceptibility to Mercury15590114
D008628MercuryMercury results in increased expression of ABCC2 mRNA15590114
D008628MercuryMercury results in increased expression of ABCC2 protein15590114
D008628MercuryABCC2 protein results in increased secretion of Mercury21266201
D008628MercuryMercury results in increased expression of ABCC2 mRNA21266201
D008628MercuryABCC2 gene SNP affects the susceptibility to and affects the abundance of Mercury23052037|2726278
D008628MercuryABCC2 protein affects the transport of [Mercury co-treated with Cysteine]21134393
D008628MercuryABCC2 protein results in increased transport of Mercury24039982
D008628MercuryAdenosine Triphosphate affects the reaction [ABCC2 protein results in increased transport of Mercury]24039982
D008628MercuryABCC2 gene mutant form affects the susceptibility to Mercury25145654
D008628MercuryABCC2 protein results in increased export of Mercury25145654
D008628MercuryABCC2 gene mutant form affects the susceptibility to Mercury25145654
D008628MercuryABCC2 protein affects the transport of Mercury23059061
D008628MercuryABCC2 protein results in increased export of Mercury25145654
C019470mesaconitine[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of mesaconitine23200901
D008687MetforminMetformin results in increased expression of ABCC2 mRNA19022234
D008701MethapyrileneMethapyrilene results in increased expression of ABCC2 mRNA22484513|2852906
D008715Methionine[LEP gene mutant form co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA24384915
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA24384915
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 mRNA24384915
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of ABCC2 protein17640958|2438491
D008727MethotrexateABCC2 gene polymorphism affects the susceptibility to and affects the metabolism of Methotrexate25007187
D008727MethotrexateABCC2 gene SNP affects the susceptibility to Methotrexate18381794|2322220
D008727MethotrexateABCC2 polymorphism results in increased susceptibility to Methotrexate21887680
D008727MethotrexateABCC2 protein affects the export of and results in decreased susceptibility to Methotrexate15864128
D008727MethotrexateABCC2 protein affects the transport of Methotrexate11500505
D008727MethotrexateABCC2 protein mutant form results in increased susceptibility to Methotrexate15864128
D008727MethotrexateABCC2 protein results in decreased susceptibility to Methotrexate19394316|2209582
D008727MethotrexateMethotrexate inhibits the reaction [ABCC2 protein results in increased export of Fosinopril]22095822
D008727MethotrexateMethotrexate results in increased expression of ABCC2 mRNA23897011
D008727MethotrexateABCC2 protein affects the export of Methotrexate22095822
D008727MethotrexateABCC2 protein affects the reaction [Fosinopril affects the export of Methotrexate]22095822
D008727MethotrexateABCC2 protein affects the transport of Methotrexate16611851
D008727MethotrexateABCC2 protein results in increased export of Methotrexate12608533
D008727MethotrexateABCC2 protein results in increased import of Methotrexate19067394
D008727MethotrexateLeucovorin inhibits the reaction [Methotrexate results in decreased expression of ABCC2 protein]16925582
D008727MethotrexateMethotrexate results in decreased expression of ABCC2 mRNA16925582
D008727MethotrexateMethotrexate results in decreased expression of ABCC2 protein16925582
D008727MethotrexateABCC2 protein results in increased transport of Methotrexate27377006
D008727Methotrexateresveratrol inhibits the reaction [ABCC2 protein results in increased transport of Methotrexate]27377006
D008730MethoxsalenIndomethacin inhibits the reaction [Methoxsalen results in decreased activity of ABCC2 protein]29079042
D008730MethoxsalenIndomethacin inhibits the reaction [[Methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin]29079042
D008730MethoxsalenMethoxsalen results in decreased activity of ABCC2 protein29079042
D008730Methoxsalen[Methoxsalen results in decreased activity of ABCC2 protein] which results in decreased export of and results in increased abundance of Daunorubicin29079042
D008730MethoxsalenMethoxsalen results in decreased expression of ABCC2 mRNA29079042
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ABCC2 mRNA17961207
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ABCC2 mRNA23103053
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ABCC2 mRNA27720909
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ABCC2 mRNA17083914
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ABCC2 mRNA28536007
C030589methylmercury cysteineABCC2 protein affects the transport of methylmercury cysteine21134393
C030589methylmercury cysteineABCC2 protein affects the susceptibility to methylmercury cysteine21134393
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ABCC2 mRNA26011545
D008795MetronidazoleMetronidazole results in decreased expression of ABCC2 mRNA24657338
C026483midecamycinmidecamycin results in decreased activity of ABCC2 protein15618715
C026483midecamycinmidecamycin results in decreased activity of ABCC2 protein15618715
D015735MifepristoneMifepristone results in increased expression of ABCC2 mRNA15456840
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate affects the expression of ABCC2 mRNA22401849
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of ABCC2 mRNA24091636
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of ABCC2 mRNA16436460
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of ABCC2 protein16436460
C093875montelukastmontelukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]19952419
C093875montelukastmontelukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel]19952419
C093875montelukastmontelukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]19952419
C500085muraglitazarmuraglitazar results in decreased expression of ABCC2 mRNA21515302
D009173Mycophenolic AcidABCC2 protein results in increased metabolism of Mycophenolic Acid18498916
C113145mycophenolic acid glucuronideABCC2 protein affects the transport of mycophenolic acid glucuronide15816878
C113145mycophenolic acid glucuronideCyclosporine inhibits the reaction [ABCC2 protein affects the transport of mycophenolic acid glucuronide]15816878
C040015myricetinmyricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]15896345
C040015myricetinmyricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]15896345
C040015myricetinmyricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]15896345
C040015myricetinmyricetin results in decreased activity of ABCC2 protein15670588
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of ABCC2 mRNA"29244179
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Bucladesine results in increased expression of ABCC2 protein]26049102
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Chenodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]27743861
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]27743861
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA25655198
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC2 protein25655198
D0150581-NaphthylisothiocyanateABCC2 results in increased susceptibility to 1-Naphthylisothiocyanate20551477
D0150581-Naphthylisothiocyanatealisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]25655198
D0150581-Naphthylisothiocyanatealisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]25655198
D0150581-Naphthylisothiocyanate"pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]"25655198
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA25380136|2541837
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein25418378|2770259
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA27317372|2776567
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of ABCC2 protein27317372
D0150581-Naphthylisothiocyanate"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]"27702592
D0150581-Naphthylisothiocyanate"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]"27702592
D0150581-Naphthylisothiocyanatedioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]27317372
D0150581-Naphthylisothiocyanatedioscin promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 protein]27317372
D0150581-Naphthylisothiocyanateresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]25418378
D0150581-Naphthylisothiocyanateresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]25418378
D0150581-NaphthylisothiocyanateU 0126 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]27702592
D0150581-NaphthylisothiocyanateU 0126 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]27702592
D0150581-NaphthylisothiocyanateUrsodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]25418378
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate binds to ABCC2 protein22521610
D0150581-NaphthylisothiocyanateABCC2 protein affects the susceptibility to 1-Naphthylisothiocyanate22521610
D0150581-NaphthylisothiocyanateABCC2 protein results in increased transport of [1-Naphthylisothiocyanate binds to Glutathione]21070799
D019888NelfinavirABCC2 protein affects the transport of Nelfinavir16041239
D009355Neomycin[Cephalothin co-treated with Neomycin] results in increased expression of ABCC2 mRNA24657338
D009532NickelNickel results in decreased expression of ABCC2 mRNA24084258
D009543NifedipineNifedipine inhibits the reaction [Cadmium Chloride results in decreased activity of ABCC2 protein]11961059
D009543NifedipineNifedipine inhibits the reaction [Mercuric Chloride results in decreased activity of ABCC2 protein]11961059
D009543NifedipineNifedipine results in increased expression of ABCC2 mRNA12206135
C012655nimesulidenimesulide results in increased expression of ABCC2 mRNA24136188
D009569Nitric OxideABCC2 affects the reaction [Ursodeoxycholic Acid results in increased secretion of Nitric Oxide]20683964
D026422S-NitrosoglutathioneABCC2 affects the transport of S-Nitrosoglutathione20683964
D015739NocodazoleNocodazole results in decreased expression of ABCC2 mRNA10691972
D015739NocodazoleNocodazole results in decreased expression of ABCC2 protein10691972
C017576norgestimatenorgestimate results in decreased activity of ABCC2 protein16049127
C072936notoginsenoside R1ABCC2 protein results in increased transport of notoginsenoside R125297453
C072936notoginsenoside R1ABCC2 protein results in increased transport of notoginsenoside R125297453
C042670N-vinyl-2-pyrrolidinone[N-vinyl-2-pyrrolidinone binds to N-vinyl-2-pyrrolidinone] which results in increased expression of ABCC2 mRNA22037397
C464660obeticholic acidobeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA]27255380
C464660obeticholic acidobeticholic acid results in increased expression of ABCC2 mRNA15644430
C025589ochratoxin AABCC2 protein affects the export of ochratoxin A15955639
C025589ochratoxin AABCC2 protein affects the transport of ochratoxin A19505989|2853267
C025589ochratoxin Abiochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin Achrysin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin AGenistein inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin Aochratoxin A results in decreased expression of ABCC2 mRNA26505656
C025589ochratoxin APolyphenols inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin APolyphenols metabolite inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin AQuercetin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin Aresveratrol inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C025589ochratoxin AABCC2 protein affects the transport of ochratoxin A28532671
C025589ochratoxin Aochratoxin A results in decreased expression of ABCC2 mRNA16251485|2335814
C025589ochratoxin Aochratoxin A results in increased expression of ABCC2 mRNA29126803
C437965olmesartanABCC2 protein affects the transport of olmesartan19505989
C026209oltiprazoltipraz results in increased expression of ABCC2 mRNA16837569
C026209oltiprazoltipraz results in increased expression of ABCC2 protein25752797
C026209oltipraz[Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC2 protein18032408
C026209oltipraz[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA15833929
C026209oltiprazoltipraz results in increased expression of ABCC2 mRNA15833929
C026209oltiprazoltipraz results in increased expression of ABCC2 mRNA12920174
C026209oltiprazoltipraz results in increased expression of ABCC2 protein12920174
D015525Fatty Acids, Omega-3"Fatty Acids, Omega-3 results in decreased expression of ABCC2 mRNA"23333450
C016340o,p'-DDT"o,p'-DDT results in increased expression of ABCC2 mRNA"24464585
D016566Organoselenium Compounds[Organoselenium Compounds binds to Copper] which results in increased expression of ABCC2 mRNA25167922
D009966Orphenadrine[Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA23665939
D008939MitotaneMitotane results in increased expression of ABCC2 mRNA25542188
D010100OxygenCA9 mutant form inhibits the reaction [[Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of ABCC2 mRNA]26305601
D010100Oxygen[Oxygen deficiency results in increased expression of CA9 mRNA] which results in increased expression of ABCC2 mRNA26305601
D017239PaclitaxelABCC2 protein affects the susceptibility to Paclitaxel15645438
D017239PaclitaxelABCC2 protein affects the transport of Paclitaxel15849751
D017239PaclitaxelABCC2 protein results in decreased susceptibility to Paclitaxel15849751
D017239PaclitaxelABCC2 protein results in increased export of Paclitaxel19952419
D017239Paclitaxelmontelukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel]19952419
D017239PaclitaxelPaclitaxel affects the expression of ABCC2 mRNA20737486
D017239PaclitaxelProbenecid promotes the reaction [ABCC2 protein affects the transport of Paclitaxel]15849751
D017239PaclitaxelProbenecid promotes the reaction [ABCC2 protein results in decreased susceptibility to Paclitaxel]15849751
D017239Paclitaxelverlukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel]19952419
D017239PaclitaxelPaclitaxel results in increased expression of ABCC2 mRNA28242239
D017239PaclitaxelPaclitaxel results in increased expression of ABCC2 protein28242239
C064276pantoprazolepantoprazole promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717
D010269ParaquatParaquat affects the expression of ABCC2 mRNA25064622
D017374ParoxetineParoxetine results in increased expression of ABCC2 protein12524417
D052638Particulate MatterParticulate Matter results in decreased activity of ABCC2 protein25803276
D052638Particulate MatterParticulate Matter results in increased expression of ABCC2 protein18474546
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of ABCC2 mRNA"25510870
D020881Enkephalin, D-Penicillamine (2,5)-"ABCC2 protein affects the export of Enkephalin, D-Penicillamine (2,5)-"15528320
D010400Penicillin GPenicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717
D010400Penicillin GPenicillin G results in increased activity of ABCC2 protein15904671
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of ABCC2 mRNA18978342
D010416PentachlorophenolPentachlorophenol results in increased expression of ABCC2 mRNA23892564
C036567perfluorodecanoic acidperfluorodecanoic acid results in increased expression of ABCC2 mRNA27344344
C036567perfluorodecanoic acidPPARA protein affects the reaction [perfluorodecanoic acid results in increased expression of ABCC2 mRNA]27344344
C584865perfluorononanoic acidperfluorononanoic acid results in increased expression of ABCC2 mRNA29112762
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of ABCC2 mRNA23602845
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of ABCC2 mRNA18692542|2104636
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ABCC2 mRNA17681415
D010480PerhexilinePerhexiline results in increased expression of ABCC2 mRNA27765674
D010578PetroleumPetroleum results in increased expression of ABCC2 mRNA25208076
D010590PhalloidinePhalloidine results in decreased localization of ABCC2 protein12169763
C058305phenethyl isothiocyanateABCC2 protein affects the export of phenethyl isothiocyanate16002050
C058305phenethyl isothiocyanateGlutathione promotes the reaction [ABCC2 protein affects the export of phenethyl isothiocyanate]16002050
D010634PhenobarbitalPhenobarbital affects the expression of ABCC2 mRNA19159669
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC2 mRNA16837569|1908454
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC2 protein16837569
D010634PhenobarbitalPhenobarbital affects the expression of ABCC2 mRNA23091169
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC2 mRNA15986414|1927001
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC2 protein15986414
D010634PhenobarbitalKN 62 inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]18473823
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC2 mRNA11328961|1916217
D010634PhenobarbitalPhenobarbital results in increased expression of ABCC2 protein15908472|1847382
D010634PhenobarbitalTetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]18473823
C016651phenolphthalein glucuronidephenolphthalein glucuronide inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C016651phenolphthalein glucuronideABCC2 protein affects the export of phenolphthalein glucuronide11348857
D010637PhenolsulfonphthaleinABCC2 protein affects the export of Phenolsulfonphthalein15618741
D010672PhenytoinABCC2 protein affects the susceptibility to Phenytoin17376120
D010672PhenytoinABCC2 protein affects the transport of Phenytoin12663688|1463631
D010672PhenytoinKN 62 inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein]18473823
D010672PhenytoinPhenytoin results in increased expression of ABCC2 protein18473823
D010672PhenytoinTetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein]18473823
D010695PhlorhizinABCC2 protein results in increased uptake of Phlorhizin14570756
D010695Phlorhizinverlukast promotes the reaction [ABCC2 protein results in increased uptake of Phlorhizin]14570756
C008905physcionephyscione results in decreased expression of ABCC2 mRNA28161596
C008905physcionephyscione results in decreased expression of ABCC2 protein28161596
D010862PilocarpinePilocarpine results in increased expression of ABCC2 protein16504477
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of ABCC2 mRNA19690152
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCC2 mRNA19710929
C006253pirinixic acidpirinixic acid results in decreased expression of ABCC2 mRNA19162173|2131816
C108475pitavastatinABCC2 protein affects the transport of pitavastatin15955871
C108475pitavastatinABCC2 protein binds to and results in increased uptake of pitavastatin analog23562342
C108475pitavastatin"pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C108475pitavastatinABCC2 protein binds to and results in increased uptake of pitavastatin analog23562342
C108475pitavastatin"pitavastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
C410026PKI 166ABCC2 protein affects the transport of PKI 166 metabolite15280219
C410026PKI 166ABCC2 protein affects the transport of PKI 166 metabolite15280219
D010936Plant ExtractsPlant Extracts results in decreased activity of ABCC2 protein15729621
D010936Plant ExtractsPlant Extracts results in increased expression of ABCC2 mRNA18351577
D010984PlatinumABCC2 protein results in decreased susceptibility to Platinum15688364
C422648pluronic block copolymer p85pluronic block copolymer p85 results in decreased folding of and results in decreased activity of ABCC2 protein15648254
C058229polydatinABCC2 protein affects the export of polydatin15686436
D059808PolyphenolsPolyphenols inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
D059808PolyphenolsPolyphenols metabolite inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
D011192Potassium DichromatePotassium Dichromate results in increased expression of ABCC2 mRNA22580103
D017035PravastatinABCC2 protein affects the export of Pravastatin15901800
D017035PravastatinABCC2 protein binds to and results in increased uptake of Pravastatin analog23562342
D017035Pravastatin"Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D017035PravastatinABCC2 protein affects the transport of Pravastatin15955871
D017035PravastatinABCC2 protein binds to and results in increased uptake of Pravastatin analog23562342
D017035Pravastatin"Pravastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D017035Pravastatin"Pravastatin promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"24909372
D017035PravastatinPravastatin results in increased expression of ABCC2 protein24909372
D017035PravastatinABCC2 protein affects the transport of Pravastatin15901796
C023617pregna-4,17-diene-3,16-dione"pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCC2 mRNA]]"25655198
C071461pregnenolone 16-acetonitrile[pregnenolone 16-acetonitrile binds to and results in increased activity of NR1I2 protein] which results in increased expression of ABCC2 mRNA21311750
D011285Pregnenolone CarbonitrileEndotoxins inhibits the reaction [Pregnenolone Carbonitrile results in increased expression of ABCC2 mRNA]15456840
D011285Pregnenolone Carbonitrile[Pregnenolone Carbonitrile co-treated with NR1I2 protein mutant form] results in increased expression of ABCC2 mRNA22496397
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC2 mRNA15456840|2249639
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC2 mRNA19118567|1916217
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of ABCC2 protein15917434
D011335Proadifen[Proadifen co-treated with Cisplatin] results in increased expression of ABCC2 protein26721606
D011335ProadifenProadifen results in decreased expression of ABCC2 protein26721606
D011339ProbenecidProbenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]11477083
D011339Probenecid"Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]"27450509
D011339ProbenecidProbenecid promotes the reaction [ABCC2 protein affects the transport of docetaxel]15849751
D011339ProbenecidProbenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12704183
D011339ProbenecidProbenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]15849751
D011339ProbenecidProbenecid promotes the reaction [ABCC2 protein affects the transport of Paclitaxel]15849751
D011339ProbenecidProbenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine]15849751
D011339ProbenecidProbenecid promotes the reaction [ABCC2 protein results in decreased susceptibility to Paclitaxel]15849751
D011339ProbenecidProbenecid results in increased activity of ABCC2 protein15849751|1747860
D011339ProbenecidABCC2 protein results in increased export of Probenecid12608533
D011339Probenecid[Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite20089784
D011339Probenecid[Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium19853032
D011339ProbenecidProbenecid results in increased activity of ABCC2 protein15904671
D011339ProbenecidProbenecid results in decreased activity of ABCC2 protein20089784
C045362prochloraz[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ABCC2 mRNA29038839
C045362prochlorazprochloraz results in increased expression of ABCC2 mRNA29038839
D011374ProgesteroneProgesterone results in decreased activity of ABCC2 protein16049127
D019946Propylene Glycol[Acetaminophen co-treated with Propylene Glycol] results in increased expression of ABCC2 mRNA17934960
D011433PropranololPropranolol results in increased expression of ABCC2 mRNA22559005
D011441PropylthiouracilPropylthiouracil results in increased expression of ABCC2 mRNA24780913
D047428Protein Kinase Inhibitors"Protein Kinase Inhibitors inhibits the reaction [[EGF protein co-treated with 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone] results in decreased activity of ABCC2 protein]"25813982
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]25813982
C074191prulifloxacinABCC2 protein affects the transport of prulifloxacin metabolite15618759
D011718Pyrazinamideobeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCC2 mRNA]27255380
D011718PyrazinamidePyrazinamide results in decreased expression of ABCC2 mRNA27255380
D011718PyrazinamidePyrazinamide results in decreased expression of ABCC2 protein27255380
D011759PyrrolidinesPyrrolidines analog results in decreased expression of ABCC2 mRNA26365562
D011794QuercetinQuercetin inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
D011794QuercetinQuercetin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]11408547
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased expression of ABCC211264000
C087120RES 701-1RES 701-1 inhibits the reaction [Cadmium Chloride results in decreased activity of ABCC2 protein]11961059
C087120RES 701-1RES 701-1 inhibits the reaction [Mercuric Chloride results in decreased activity of ABCC2 protein]11961059
C059514resveratrolABCC2 protein affects the export of resveratrol15686436
C059514resveratrolresveratrol inhibits the reaction [ABCC2 protein affects the export of ochratoxin A]15955639
C059514resveratrolresveratrol inhibits the reaction [Genistein promotes the reaction [RXRA protein binds to ABCC2 promoter]]21689630
C059514resveratrolresveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 mRNA]21689630|2639412
C059514resveratrolresveratrol inhibits the reaction [Genistein results in increased expression of ABCC2 protein]21689630|2639412
C059514resveratrolresveratrol results in decreased expression of ABCC2 mRNA26394120
C059514resveratrolresveratrol results in decreased expression of ABCC2 protein26394120
C059514resveratrol[Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite20089784
C059514resveratrolresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]25418378
C059514resveratrolresveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]25418378
C059514resveratrolresveratrol results in decreased expression of ABCC2 mRNA26394120
C059514resveratrolresveratrol results in decreased expression of ABCC2 protein26394120
C059514resveratrol[verlukast results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite20089784
C059514resveratrolresveratrol inhibits the reaction [ABCC2 protein results in increased transport of Methotrexate]27377006
D012293RifampinRifampin results in increased expression of ABCC2 mRNA22559005
D012293RifampinABCC2 protein affects the export of Rifampin15652233
D012293Rifampin[Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein16952291
D012293RifampinRifampin results in increased expression of ABCC216952291
D012293RifampinRifampin results in increased expression of ABCC2 mRNA11836020|1220613
D012293RifampinRifampin results in increased expression of ABCC2 protein11836020
D012293RifampinRifampin results in increased expression of ABCC2 mRNA25542188
C040014robinetinrobinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon]15670588
C040014robinetinrobinetin results in decreased activity of ABCC2 protein15670588
C089730rosiglitazonerosiglitazone results in decreased activity of ABCC2 protein22646477
C089730rosiglitazonerosiglitazone results in increased expression of ABCC2 mRNA25572481
D000068718Rosuvastatin CalciumABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog23562342
D000068718Rosuvastatin Calcium"Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D000068718Rosuvastatin CalciumABCC2 protein affects the secretion of Rosuvastatin Calcium19853032
D000068718Rosuvastatin CalciumABCC2 protein binds to and results in increased uptake of Rosuvastatin Calcium analog23562342
D000068718Rosuvastatin Calcium[Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium19853032
D000068718Rosuvastatin Calcium[Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium19853032
D000068718Rosuvastatin Calcium"Rosuvastatin Calcium analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D000068718Rosuvastatin Calcium"Rosuvastatin Calcium promotes the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein]"24909372
D000068718Rosuvastatin CalciumRosuvastatin Calcium results in increased expression of ABCC2 protein24909372
D000068718Rosuvastatin Calcium[Sulfasalazine results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium19853032
C079905rubitecanrubitecan results in increased expression of ABCC2 mRNA15342794
C064116S-(1,1,2,2-tetrafluoroethyl)cysteine"S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of ABCC2 mRNA"16678137
C049705S-1,2-dichlorovinyl-N-acetylcysteine"ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine"20060011
C049705S-1,2-dichlorovinyl-N-acetylcysteine"Adenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of S-1,2-dichlorovinyl-N-acetylcysteine]"20060011
C030190S-(2,4-dinitrophenyl)glutathione"ABCC2 protein affects the transport of S-(2,4-dinitrophenyl)glutathione"15846474|9525973
C030190S-(2,4-dinitrophenyl)glutathione"ABCC2 protein affects the transport of S-(2,4-dinitrophenyl)glutathione"15652244|1590134
C030190S-(2,4-dinitrophenyl)glutathione"ABCC2 protein results in increased export of S-(2,4-dinitrophenyl)glutathione"19067394
C030190S-(2,4-dinitrophenyl)glutathione"ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione"15276087|9067317
C030190S-(2,4-dinitrophenyl)glutathione"Acetaminophen promotes the reaction [ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione]"15276087
C030190S-(2,4-dinitrophenyl)glutathione"[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
C030190S-(2,4-dinitrophenyl)glutathione"[Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
C030190S-(2,4-dinitrophenyl)glutathione"S-(2,4-dinitrophenyl)glutathione inhibits the reaction [ABCC2 protein results in increased transport of temocaprilat]"9067317
C030190S-(2,4-dinitrophenyl)glutathione"[Spironolactone results in increased expression of ABCC2 protein] which results in increased transport of S-(2,4-dinitrophenyl)glutathione"19766108
C030190S-(2,4-dinitrophenyl)glutathione"[sulfanitran results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
C030190S-(2,4-dinitrophenyl)glutathione"temocaprilat inhibits the reaction [ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione]"9067317
C030190S-(2,4-dinitrophenyl)glutathione"Ursodeoxycholic Acid promotes the reaction [ABCC2 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]"19067394
D019258SaquinavirABCC2 protein affects the transport of Saquinavir12702717
D019258SaquinavirABCC2 protein affects the export of Saquinavir15832500
D019258SaquinavirABCC2 protein results in increased export of Saquinavir18535159|1995241
D019258Saquinavirmontelukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]19952419
D019258Saquinavirverlukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]19952419
D012643Selenium[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA11444866
C009237senecioninesenecionine results in decreased expression of ABCC2 mRNA26100227
C009250sevofluranesevoflurane affects the expression of ABCC2 mRNA15967596
D012834SilverSilver results in increased expression of ABCC2 mRNA25976698
D019821SimvastatinABCC2 polymorphism affects the susceptibility to Simvastatin22186618
D019821SimvastatinABCC2 protein binds to and results in increased uptake of Simvastatin analog23562342
D019821Simvastatin"Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D019821SimvastatinSimvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D019821SimvastatinSimvastatin analog results in decreased activity of ABCC2 protein15616150
D019821SimvastatinABCC2 protein binds to and results in increased uptake of Simvastatin analog23562342
D019821Simvastatin"Simvastatin analog inhibits the reaction [ABCC2 protein binds to and results in increased uptake of 5(6)-carboxy-2',7'-dichlorofluorescein]"23562342
D019821SimvastatinSimvastatin analog inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]15616150
D019821SimvastatinSimvastatin analog results in decreased activity of ABCC2 protein15616150
D019821SimvastatinSimvastatin results in decreased expression of ABCC2 mRNA27765674
D020123SirolimusSirolimus results in decreased expression of ABCC2 mRNA11589784
C009277sodium arsenatesodium arsenate results in increased expression of ABCC2 mRNA12727804
C009277sodium arsenatesodium arsenate results in increased expression of ABCC2 mRNA11408547
C009277sodium arsenatesodium arsenate results in increased expression of ABCC2 protein11408547
C017947sodium arseniteNFE2L2A protein affects the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]27306194
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 mRNA27306194
C017947sodium arsenitesodium arsenite results in increased activity of ABCC2 protein17324950
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 protein17324950
C017947sodium arseniteABCC2 results in decreased susceptibility to sodium arsenite16672223
C017947sodium arsenitesodium arsenite affects the expression of ABCC2 protein24391030
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 mRNA11408547|1272780
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 protein11408547
C017947sodium arseniteSPDL1 protein promotes the reaction [sodium arsenite results in increased expression of ABCC2 protein]24391030
C017947sodium arsenite[Dietary Fats co-treated with sodium arsenite] results in increased expression of ABCC2 mRNA26890134
C017947sodium arseniteMT1 gene mutant form affects the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]25485709
C017947sodium arseniteMT2 gene mutant form affects the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]25485709
C017947sodium arsenite"sodium arsenite inhibits the reaction [soybean oil, phospholipid emulsion results in decreased expression of ABCC2 mRNA]"26890134
C017947sodium arsenitesodium arsenite results in decreased expression of ABCC2 mRNA29108910
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 mRNA20008137|2548570
C017947sodium arseniteABCC2 protein results in decreased susceptibility to sodium arsenite11455017
C017947sodium arseniteDactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]11408547
C017947sodium arseniteQuercetin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]11408547
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 mRNA11408547|1145501
C017947sodium arsenitesodium arsenite results in increased expression of ABCC2 protein11408547|1145501
D017693Sodium BicarbonateSodium Bicarbonate results in increased expression of ABCC2 mRNA29126803
C016104sodium bichromatesodium bichromate results in decreased expression of ABCC2 mRNA24612858
C016104sodium bichromatesodium bichromate results in decreased expression of ABCC2 mRNA22155349
C016104sodium bichromatesodium bichromate results in increased expression of ABCC2 mRNA22155349
C016104sodium bichromatesodium bichromate affects the expression of ABCC2 mRNA22110744
D012965Sodium Chloride[Acetaminophen co-treated with Sodium Chloride] results in increased expression of ABCC2 mRNA17934960
C471405sorafenibABCC2 affects the susceptibility to sorafenib24244338
D013024Soybean OilSoybean Oil affects the expression of ABCC2 mRNA15770074
C545823soybean oil, phospholipid emulsion"sodium arsenite inhibits the reaction [soybean oil, phospholipid emulsion results in decreased expression of ABCC2 mRNA]"26890134
C545823soybean oil, phospholipid emulsion"soybean oil, phospholipid emulsion results in decreased expression of ABCC2 mRNA"26890134
D013148Spironolactone[Ethinyl Estradiol co-treated with Spironolactone] results in increased expression of ABCC2 protein17686906
D013148SpironolactoneKetoconazole inhibits the reaction [Spironolactone results in increased expression of ABCC2 mRNA]19766108
D013148SpironolactoneSpironolactone results in increased expression of ABCC2 mRNA17686906|1976610
D013148SpironolactoneSpironolactone results in increased expression of ABCC2 protein15652244|1768690
D013148Spironolactone"[Spironolactone results in increased expression of ABCC2 protein] which results in increased transport of S-(2,4-dinitrophenyl)glutathione"19766108
C525422SRT1720SRT1720 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27818225
C525422SRT1720SRT1720 inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 protein]27818225
C025906stilbene oxidestilbene oxide results in increased expression of ABCC2 mRNA12920174
C025906stilbene oxidestilbene oxide results in increased expression of ABCC2 protein12920174
D013311StreptozocinStreptozocin results in increased expression of ABCC2 mRNA22531820|2331917
D013311StreptozocinStreptozocin results in increased expression of ABCC2 protein23319174
D013311StreptozocinStreptozocin results in increased expression of ABCC2 mRNA11752103
D004113SuccimerABCC2 results in increased transport of Succimer metabolite19063911
D004113SuccimerABCC2 protein affects the reaction [Succimer binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]18511429
D004113SuccimerABCC2 protein binds to and results in increased secretion of [Succimer binds to [Mercuric Chloride binds to Cysteine]]18511429
D004113SuccimerABCC2 protein results in increased transport of Succimer metabolite17940195
C009349sulfanitransulfanitran results in increased activity of ABCC2 protein12702717
C009349sulfanitransulfanitran promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]12702717
C009349sulfanitran"[sulfanitran results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]"19782883
D012460Sulfasalazine[Sulfasalazine results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium19853032
D013442SulfinpyrazoneSulfinpyrazone results in decreased activity of ABCC2 protein14569069
D013442SulfinpyrazoneSulfinpyrazone inhibits the reaction [ABCC2 protein results in increased export of Vinblastine]11834888
D013448SulfobromophthaleinABCC2 protein affects the export of Sulfobromophthalein16046661
D013448SulfobromophthaleinABCC2 protein affects the transport of Sulfobromophthalein17329856
C016766sulforafansulforafan results in increased expression of ABCC2 mRNA27306194
C016766sulforafansulforafan results in increased expression of ABCC2 mRNA11264000|1589633
C016766sulforafansulforafan results in increased expression of ABCC2 protein11264000
C016766sulforafansulforafan results in increased expression of ABCC2 mRNA11264000
C016766sulforafansulforafan results in increased expression of ABCC2 protein11264000
C473478sunitinibsunitinib results in increased expression of ABCC2 mRNA26797788
C473478sunitinibsunitinib results in increased expression of ABCC2 protein26797788
D0150852,4,5-Trichlorophenoxyacetic Acid"2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA"16426233
D0150852,4,5-Trichlorophenoxyacetic Acid"2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCC2 mRNA"16426233
D013605T-2 ToxinT-2 Toxin results in decreased expression of ABCC2 mRNA23313610
C557331TAK-875TAK-875 affects the activity of ABCC2 protein28108665
C557331TAK-875TAK-875 affects the reaction [ABCC2 protein results in increased transport of Bile Acids and Salts]28108665
C557331TAK-875TAK-875 analog results in decreased activity of ABCC2 protein28108665
C557331TAK-875TAK-875 inhibits the reaction [ABCC2 protein results in increased transport of Bile Acids and Salts]28108665
D013629TamoxifenABCC2 gene affects the susceptibility to Tamoxifen20124171
D013629TamoxifenTamoxifen results in increased expression of ABCC2 mRNA27765674
D013654TaurineTaurine results in increased expression of ABCC2 protein12706339
D013655Taurochenodeoxycholic AcidTaurochenodeoxycholic Acid results in increased expression of ABCC2 protein11672435
D013656Taurocholic AcidTaurocholic Acid results in increased expression of ABCC2 mRNA27160211
D013656Taurocholic AcidTaurocholic Acid results in increased activity of ABCC2 protein15904671
D013656Taurocholic AcidTaurocholic Acid results in increased activity of ABCC2 protein modified form15904671
D013656Taurocholic AcidTaurocholic Acid results in increased expression of and results in increased activity of ABCC2 protein12644037
C037351tauromuricholic acidtauromuricholic acid results in increased expression of ABCC2 protein11672435
C037351tauromuricholic acidtauromuricholic acid results in increased expression of and results in increased activity of ABCC2 protein12644037
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased expression of ABCC2 protein11672435
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in increased expression of and results in increased activity of ABCC2 protein12644037
C069156temocaprilatABCC2 protein affects the transport of temocaprilat15507541
C069156temocaprilatABCC2 protein affects the transport of temocaprilat11348856|1550754
C069156temocaprilatABCC2 protein results in increased transport of temocaprilat9067317
C069156temocaprilatAdenosine Triphosphate promotes the reaction [ABCC2 protein results in increased transport of temocaprilat]9067317
C069156temocaprilat"S-(2,4-dinitrophenyl)glutathione inhibits the reaction [ABCC2 protein results in increased transport of temocaprilat]"9067317
C069156temocaprilat"temocaprilat inhibits the reaction [ABCC2 protein results in increased transport of S-(2,4-dinitrophenyl)glutathione]"9067317
C047246temozolomideABCC2 mRNA affects the susceptibility to temozolomide16365179
C041359terbinafineABCC2 affects the susceptibility to terbinafine18466103
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in increased expression of ABCC2 mRNA]20032058
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ABCC2 mRNA27618130
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of ABCC2 mRNA]22496397
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ABCC2 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of ABCC2 mRNA15833929
D013749Tetrachlorodibenzodioxin"Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of ABCC2 mRNA]"17627975
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ABCC2 mRNA15833929|2109521
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ABCC2 mRNA28341572
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of ABCC2 protein21048045
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of and results in increased activity of ABCC2 protein22472606
D013752TetracyclineTetracycline affects the expression of ABCC2 mRNA25064622
D013752TetracyclineTetracycline results in decreased expression of ABCC2 mRNA27765674
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]18473823
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]18473823
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein]18473823
D013853ThioacetamideThioacetamide affects the expression of ABCC2 mRNA25064622
D013853ThioacetamideThioacetamide results in increased expression of ABCC2 mRNA23411599|2622270
D013974ThyroxineABCC2 results in decreased abundance of Thyroxine19211616
C054785thyroxine glucuronideABCC2 affects the abundance of thyroxine glucuronide19211616
C059205tiagabinetiagabine results in increased expression of ABCC2 protein18473823
C050504tianeptinetianeptine results in increased expression of ABCC2 mRNA27765674
D013988TiclopidineTiclopidine results in decreased activity of ABCC2 protein22646477
D013988TiclopidineTiclopidine results in increased expression of ABCC2 mRNA27765674
D014028Tobacco Smoke Pollution"Tobacco Smoke Pollution inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]"27450509
C116664tolvaptantolvaptan metabolite results in decreased activity of ABCC2 protein26507107
C052342topiramatetopiramate results in increased expression of ABCC2 protein18473823
D019772Topotecan[chrysin results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan20457140
D019772TopotecanTopotecan results in increased expression of ABCC2 protein20457140
D019772Topotecan[verlukast results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan20457140
D014212TretinoinTretinoin results in decreased expression of ABCC2 mRNA16604517
C012589trichostatin Atrichostatin A results in decreased expression of ABCC2 mRNA10691972
C012589trichostatin Atrichostatin A results in decreased expression of ABCC2 protein10691972
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of ABCC2 mRNA16436460
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of ABCC2 protein16436460
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of ABCC2 mRNA12044520
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of ABCC2 protein12044520
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ABCC2 mRNA"26179874
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate results in increased expression of ABCC2 protein24685621
C057693troglitazone[SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of troglitazone analog19628752
C057693troglitazonetroglitazone results in decreased activity of ABCC2 protein22646477
C057693troglitazonetroglitazone results in increased expression of ABCC2 mRNA19022234
D014217TroleandomycinTroleandomycin results in increased expression of ABCC2 mRNA23064032
D014425TurpentineTurpentine results in decreased expression of ABCC2 mRNA15313196
C447031tyrphostin AG 1024tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]29090346
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]25813982
C113580U 0126U 0126 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]27702592
C113580U 0126U 0126 inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 protein]27702592
D014494UnithiolABCC2 results in increased transport of Unithiol metabolite19063911
D014494UnithiolABCC2 protein affects the reaction [Unithiol binds to and results in increased secretion of [Mercuric Chloride binds to Cysteine]]18511429
D014494UnithiolABCC2 protein binds to and results in increased secretion of [Unithiol binds to [Mercuric Chloride binds to Cysteine]]18511429
D014494UnithiolABCC2 protein results in increased transport of Unithiol metabolite17940195
D014501Uranium[Acetaminophen co-treated with Uranium analog] results in increased expression of ABCC2 mRNA17126469
D014501UraniumUranium analog promotes the reaction [Acetaminophen results in increased expression of ABCC2 mRNA]17126469
D014502Uranyl NitrateUranyl Nitrate results in increased expression of ABCC2 mRNA24146111
D014520UrethaneUrethane results in decreased expression of ABCC2 mRNA28818685
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC216952291
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC2 protein15956029
D014580Ursodeoxycholic AcidNFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of ABCC2 mRNA]18687751
D014580Ursodeoxycholic AcidNFE2L2 affects the reaction [Ursodeoxycholic Acid results in increased expression of ABCC2 protein]18687751
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC2 mRNA11438506|1297195
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC2 protein11438506|1868775
D014580Ursodeoxycholic AcidABCC2 affects the reaction [Ursodeoxycholic Acid results in increased secretion of Nitric Oxide]20683964
D014580Ursodeoxycholic AcidN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]]27743861
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid affects the expression of ABCC2 mRNA12606635
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid affects the expression of ABCC2 protein12606635
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of ABCC2 mRNA]25418378
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased activity of ABCC2 protein]15843489
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of ABCC2 mRNA]27743861
D014580Ursodeoxycholic Acid"Ursodeoxycholic Acid promotes the reaction [ABCC2 protein results in increased export of S-(2,4-dinitrophenyl)glutathione]"19067394
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased activity of ABCC2 protein15843489
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC2 mRNA19067394
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased expression of ABCC2 protein19067394
C066668vadimezanABCC2 protein affects the export of vadimezan metabolite15784341
C066668vadimezanABCC2 protein affects the transport of vadimezan analog15282097
C406224valdecoxibvaldecoxib results in increased expression of ABCC2 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of ABCC2 mRNA25064622
D014635Valproic AcidValproic Acid results in increased expression of ABCC2 mRNA23527032
D014635Valproic AcidValproic Acid results in increased expression of ABCC2 mRNA27160211
D014635Valproic Acid[Carbon Tetrachloride co-treated with Valproic Acid] affects the expression of ABCC2 mRNA17617793
D014635Valproic AcidValproic Acid results in decreased expression of ABCC2 mRNA21318169|2776567
D014640Vancomycin[Vancomycin co-treated with Imipenem] affects the expression of ABCC2 mRNA24657338
D001335Vehicle EmissionsVehicle Emissions results in decreased activity of ABCC2 protein25803276
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of ABCC2 gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased expression of ABCC2 protein18474546
D014700VerapamilVerapamil inhibits the reaction [ABCC2 protein affects the export of 5-carboxyfluorescein diacetate]16636798
D014700VerapamilVerapamil results in decreased activity of ABCC2 protein16026006
C059141verlukastABCC2 protein results in increased abundance of verlukast21266201
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in decreased abundance of calcein AM]21266201
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased export of calcein AM]19952419
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased export of Paclitaxel]19952419
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]19952419
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]19647055
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased transport of Leukotriene C4]27676153
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased transport of zearalenol]19647055
C059141verlukastverlukast inhibits the reaction [ABCC2 protein results in increased transport of Zearalenone]19647055
C059141verlukastverlukast inhibits the reaction [Bucladesine results in increased activity of ABCC2 protein]29052767
C059141verlukastverlukast results in decreased activity of ABCC2 protein15451006|1572962
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased export of Topotecan20457140
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylaconine23200901
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylhypaconine23200901
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of benzoylmesaconine23200901
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of hypaconitine23200901
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased transport of mesaconitine23200901
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine25844889
C059141verlukastverlukast inhibits the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]9614209
C059141verlukastABCC2 protein affects the reaction [verlukast results in decreased secretion of Chenodeoxycholic Acid]21262925
C059141verlukastverlukast results in decreased activity of ABCC2 protein15904671
C059141verlukastverlukast results in decreased activity of ABCC2 protein modified form15904671
C059141verlukast[verlukast results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite20089784
C059141verlukastverlukast promotes the reaction [ABCC2 protein results in increased uptake of Phlorhizin]14570756
C059141verlukastverlukast results in decreased activity of ABCC2 protein11455017|1249058
D014747VinblastineABCC2 protein affects the transport of Vinblastine15849751|9525973
D014747Vinblastine"[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine"25844889
D014747VinblastineProbenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine]15849751
D014747Vinblastine[verlukast results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine25844889
D014747VinblastineABCC2 protein results in decreased susceptibility to Vinblastine11455017
D014747VinblastineABCC2 protein results in increased export of Vinblastine11834888
D014747VinblastineSulfinpyrazone inhibits the reaction [ABCC2 protein results in increased export of Vinblastine]11834888
D014750VincristineABCC2 protein affects the export of and results in decreased susceptibility to Vincristine15896345
D014750VincristineABCC2 protein affects the export of Vincristine15896345
D014750VincristineABCC2 protein results in decreased susceptibility to Vincristine15896345|2209582
D014750Vincristinemyricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]15896345
D014750Vincristinemyricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]15896345
D014750Vincristinemyricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]15896345
D014750Vincristine[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC2 mRNA19944135
D014810Vitamin E[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA11444866
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased expression of ABCC2 mRNA"25208076
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased expression of ABCC2 mRNA"23246600
C009687wortmanninwortmannin affects the localization of ABCC2 protein12702492
C009687wortmanninwortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]20815017
C108830Y 27632Y 27632 results in increased expression of ABCC2 mRNA20878077
D015016Yohimbine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA28843594
C115527Z 335ABCC2 protein affects the export of Z 33512486683
C029659zearalenolABCC2 protein results in increased transport of zearalenol19647055
C029659zearalenolverlukast inhibits the reaction [ABCC2 protein results in increased transport of zearalenol]19647055
C029659zearalenolzearalenol inhibits the reaction [ABCC2 protein results in increased transport of calcein AM]19647055
C029659zearalenolzearalenol results in decreased expression of ABCC2 mRNA22310176
C029659zearalenolzearalenol results in decreased expression of ABCC2 protein22310176
C029659zearalenolzearalenol results in increased expression of ABCC2 mRNA22310176
C029659zearalenolzearalenol results in increased expression of ABCC2 protein22310176

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI17825285  21988832  
GO:0005524ATP binding-IEA-  
GO:0008514organic anion transmembrane transporter activity-TAS7559771  
GO:0015127bilirubin transmembrane transporter activity-TAS-  
GO:0019904protein domain specific binding-IEA-  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-IBA21873635  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-TAS7559771  
GO:0043225ATPase-coupled anion transmembrane transporter activity-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006855drug transmembrane transport-IEA-  
GO:0006979response to oxidative stress-IEA-  
GO:0007565female pregnancy-IEA-  
GO:0009408response to heat-IEA-  
GO:0015694mercury ion transport-IEA-  
GO:0015722canalicular bile acid transport-IEA-  
GO:0015723bilirubin transport-IEA-  
GO:0015732prostaglandin transport-IEA-  
GO:0030644cellular chloride ion homeostasis-IEA-  
GO:0031427response to methotrexate-IEA-  
GO:0033762response to glucagon-IEA-  
GO:0043627response to estrogen-IEA-  
GO:0046685response to arsenic-containing substance-IEA-  
GO:0055085transmembrane transport-IBA21873635  
GO:0055085transmembrane transport-TAS-  
GO:0070327thyroid hormone transport-IEA-  
GO:0071222cellular response to lipopolysaccharide-IEA-  
GO:0071347cellular response to interleukin-1-IEA-  
GO:0071354cellular response to interleukin-6-IEA-  
GO:0071356cellular response to tumor necrosis factor-IEA-  
GO:0071549cellular response to dexamethasone stimulus-IEA-  
GO:0099133ATP hydrolysis coupled anion transmembrane transport-IEA-  
GO:1901086benzylpenicillin metabolic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0009986cell surface-HDA19581412  
GO:0009986cell surface-IDA17825285  
GO:0016020membrane-IBA21873635  
GO:0016324apical plasma membrane-IBA21873635  
GO:0016324apical plasma membrane-IDA11093739  17825285  
GO:0031526brush border membrane-IEA-  
GO:0046581intercellular canaliculus-IEA-  
KEGG ID KEGG Term
hsa02010ABC transporters
hsa04976Bile secretion
Reactome ID Reactome Term Evidence
R-HSA-1643685DiseaseTAS
R-HSA-382551Transport of small moleculesTAS
R-HSA-382556ABC-family proteins mediated transportTAS
R-HSA-5619084ABC transporter disordersTAS
R-HSA-5619115Disorders of transmembrane transportersTAS
R-HSA-5679001Defective ABCC2 causes Dubin-Johnson syndromeTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23462698Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver. (2013 May)More VRDrug Metab Dispos
27988838Polymorphisms of Genes Encoding Multidrug Resistance Proteins as a Predictive Factor for Second-Line Docetaxel Therapy in Advanced Non-small Cell Lung Cancer. (2017 Jul)Szczyrek MPathol Oncol Res
26109419Polymorphisms in ATP-binding cassette transporter genes and interaction with diet and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study. (2015)Kopp TIScand J Gastroenterol
29681089Genetic variation in biotransformation enzymes, air pollution exposures, and risk of spina bifida. (2018 May)Padula AMAm J Med Genet A
24343710Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention. (2014 May)Nicol MRJ Clin Pharmacol
20439344Genetic variation in glutathione metabolism and DNA repair genes predicts survival of small-cell lung cancer patients. (2010 Oct)Sun ZAnn Oncol