Gene: AXDND1

126859
C1orf125
axonemal dynein light chain domain containing 1
protein-coding
1q25.2
Ensembl:ENSG00000162779 Vega:OTTHUMG00000035266 UniprotKB:Q5T1B0
NG_033075.1
SNP Mapped
2   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.696e-2 (AD)  5.964e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2274626chr1:179552797 (GRCh38.p7)G>Talcohol dependenceSNV(Single Nucleotide Variation)
rs1410587chr1:179546937 (GRCh38.p7)C>G / C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SCN11A0.558
AASS0.543
CYP4V20.534
TEAD10.534
POU2F10.534
DENND4C0.53
ZNF4430.53
ZNF7630.528
AGBL20.525
ZNF7300.523

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ADRA2C-0.351
CRH-0.347
ELFN1-0.331
KCNG1-0.33
PNOC-0.324
MAGIX-0.323
TTC9B-0.314
DNLZ-0.312
GGN-0.311
NANOS3-0.309

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D002117CalcitriolCalcitriol results in decreased expression of AXDND1 mRNA16002434
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of AXDND1 mRNA26011545
D009532NickelNickel results in decreased expression of AXDND1 mRNA24768652

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal