Gene: MYOM3

127294
-
myomesin 3
protein-coding
1p36.11
Ensembl:ENSG00000142661 MIM:616832 Vega:OTTHUMG00000002969 UniprotKB:Q5VTT5
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.063e-1 (AD)  5.649e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs4276859chr1:24089643 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CSRP30.787
TNNC10.762
MB0.749
TECRL0.749
IYD0.736
ANKRD10.723
LMOD20.714
MYBPC30.713
MYL20.712
TPO0.708

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ASPDH-0.376
SAC3D1-0.35
ZNF835-0.341
HAGHL-0.336
TMEM121-0.334
ZNF771-0.333
TMEM240-0.331
DBP-0.327
LRRC45-0.326
TEX29-0.324

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of MYOM3 mRNA"22698814|2890350
D020106AcrylamideAcrylamide results in decreased expression of MYOM3 mRNA28959563
C030935benz(a)anthracenebenz(a)anthracene results in decreased expression of MYOM3 mRNA26377693
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in decreased expression of MYOM3 mRNA26496021
C018475butyraldehydebutyraldehyde results in decreased expression of MYOM3 mRNA26079696
D002509CephaloridineCephaloridine results in increased expression of MYOM3 mRNA18500788
C026690cerous chloridecerous chloride results in increased expression of MYOM3 mRNA23573234
C031180chrysenechrysene results in increased expression of MYOM3 mRNA26377693
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of MYOM3 mRNA28962523
D004041Dietary FatsDietary Fats results in increased expression of MYOM3 mRNA18042831
C045463leflunomideleflunomide results in decreased expression of MYOM3 mRNA28988120
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of MYOM3 mRNA22401849
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of MYOM3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of MYOM3 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of MYOM3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of MYOM3 mRNA"25620056
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM3 mRNA27935865
D000073878Palm OilPalm Oil results in increased expression of MYOM3 mRNA18042831
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM3 mRNA27935865
C006253pirinixic acidpirinixic acid results in decreased expression of MYOM3 mRNA23811191
C045950propiconazolepropiconazole results in increased expression of MYOM3 mRNA21278054
C005556propionaldehydepropionaldehyde results in increased expression of MYOM3 mRNA26079696
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of MYOM3 mRNA23806026
D012834SilverSilver results in increased expression of MYOM3 mRNA27131904
D053260SootSoot results in increased expression of MYOM3 mRNA22461453
D013629TamoxifenTamoxifen results in increased expression of MYOM3 mRNA25123088
D013739Testosterone[bisphenol A co-treated with Testosterone] results in decreased expression of MYOM3 mRNA26496021
D013750TetrachloroethyleneTetrachloroethylene results in decreased expression of MYOM3 mRNA28973375
D014241TrichloroethyleneTrichloroethylene results in decreased expression of MYOM3 mRNA28973375
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of MYOM3 mRNA29024780
D014520UrethaneUrethane results in decreased expression of MYOM3 mRNA28818685
D014635Valproic AcidValproic Acid results in increased methylation of MYOM3 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0008307structural constituent of muscle-IBA21873635  
GO:0042803protein homodimerization activity-ISS-  
GO:0051015actin filament binding-IBA21873635  
GO:0051371muscle alpha-actinin binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006941striated muscle contraction-IBA21873635  
GO:0007015actin filament organization-IBA21873635  
GO:0030240skeletal muscle thin filament assembly-IBA21873635  
GO:0030241skeletal muscle myosin thick filament assembly-IBA21873635  
GO:0045214sarcomere organization-IBA21873635  
GO:0048739cardiac muscle fiber development-IBA21873635  
GO:0055003cardiac myofibril assembly-IBA21873635  
GO:0055008cardiac muscle tissue morphogenesis-IBA21873635  
GO:0071688striated muscle myosin thick filament assembly-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005859muscle myosin complex-IBA21873635  
GO:0005865striated muscle thin filament-IBA21873635  
GO:0030018Z disc-IBA21873635  
GO:0031430M band-IBA21873635  
GO:0031430M band-ISS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal