Gene info: ID 127665

Gene: ZNF648

GENE ID: 127665

Synonyms: -

Description: zinc finger protein 648

Gene type: protein-coding

Location: 1q25.3

dbXrefs: Ensembl:ENSG00000179930 Vega:OTTHUMG00000037302 UniprotKB:Q5T619

RefSeq: NC_000001.11

Retrived from: SNP Mapped

SNPs: 0 ANCO-SNPs

Phenotype: AD

# Publications: 0

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 9.170e-1 (AD) 7.719e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ACP5	0.36
SBK3	0.347
ZNF619	0.346
PCDHB15	0.338
FUOM	0.337
SP140	0.335
PCK2	0.332
WDR87	0.329
RAD51AP1	0.328
MTTP	0.328

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
WFDC8	-0.298
ADRA2C	-0.23
PAEP	-0.217
MIP	-0.201
TJP3	-0.199
RPS4Y1	-0.193
EIF1AY	-0.192
HGFAC	-0.191
ERVV-1	-0.189
LRRC10B	-0.185

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
D001151	Arsenic	Arsenic affects the methylation of ZNF648 gene	25304211

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	-	ISA	-
GO:0003677	DNA binding	-	IBA	21873635
GO:0003677	DNA binding	-	IEA	-
GO:0003700	DNA-binding transcription factor activity	-	IBA	21873635
GO:0046872	metal ion binding	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006351	transcription, DNA-templated	-	IEA	-
GO:0006355	regulation of transcription, DNA-templated	-	IBA	21873635
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	IBA	21873635
GO:0005634	nucleus	-	IEA	-

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal