Gene info: ID 1277

Gene: COL1A1

GENE ID: 1277

Synonyms: EDSARTH1|EDSC|OI1|OI2|OI3|OI4

Description: collagen type I alpha 1 chain

Gene type: protein-coding

Location: 17q21.33

dbXrefs: Ensembl:ENSG00000108821 MIM:120150 Vega:OTTHUMG00000148674 UniprotKB:P02452

RefSeq: NG_007400.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 13

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 2.024e-1 (AD) 7.121e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
COL3A1	0.796
COL6A3	0.771
MGP	0.714
GPX8	0.711
COL8A1	0.704
FBLIM1	0.693
COL1A2	0.68
STEAP4	0.67
COL14A1	0.668
FGF7	0.665

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
NEUROD6	-0.448
GALNT9	-0.43
KCNC2	-0.422
EIF4E1B	-0.417
YBX2	-0.417
KCNB2	-0.417
KCNJ3	-0.415
PVALB	-0.412
NEUROD2	-0.41
TMEM221	-0.408

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00048	Collagenase clostridium histolyticum	BiotechDrug	9001-12-1	Approved\|Investigational	Target
DB04866	Halofuginone	Small Molecule	55837-20-2	Investigational	Target
DB12872	Vonicog Alfa	BiotechDrug	109319-16-6	Approved\|Investigational	Target
DB13133	Von Willebrand Factor Human	BiotechDrug	109319-16-6	Approved\|Investigational	Target

ID	Drug Name	Action	PubMed
C006718	1,12-benzoperylene	"1,12-benzoperylene results in increased expression of COL1A1 mRNA"	26377693
C432747	1,1-dimethylbutyl-1-deoxy-Delta(9)-THC	"1,1-dimethylbutyl-1-deoxy-Delta(9)-THC results in increased expression of COL1A1 mRNA"	15313899
C097949	1,25-dihydroxyvitamin D	"U 0126 inhibits the reaction [1,25-dihydroxyvitamin D results in increased expression of COL1A1 mRNA]"	15331595
C097949	1,25-dihydroxyvitamin D	"U 0126 promotes the reaction [1,25-dihydroxyvitamin D results in increased expression of COL1A1 mRNA]"	15331595
C549500	1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea	1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]	27678262
C049325	1,2-dithiol-3-thione	"1,2-dithiol-3-thione results in decreased expression of COL1A1 mRNA"	19162173
C002448	1,2-linoleoylphosphatidylcholine	"1,2-linoleoylphosphatidylcholine inhibits the reaction [LEP protein results in increased expression of COL1A1 mRNA]"	16996477
C038983	1,3-dimethylthiourea	"1,3-dimethylthiourea inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]"	11682029
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of COL1A1 mRNA"	18281256
C097240	15-deoxy-delta(12,14)-prostaglandin J2	"15-deoxy-delta(12,14)-prostaglandin J2 results in decreased expression of COL1A1 mRNA"	12021203
C119129	18alpha-glycyrrhetinic acid	18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]	21910061
C101670	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate	2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	15703175
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in decreased expression of COL1A1 mRNA"	19095052
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein]	17030193
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	11576339
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of COL1A1 mRNA	21741227
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	neoeriocitrin inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of COL1A1 mRNA]	21741227
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of COL1A1 mRNA]	27025157
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of COL1A1 mRNA]	26053266
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of COL1A1 mRNA	17965732
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of COL1A1 protein	17965732
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [LEP protein results in increased expression of COL1A1 mRNA]	16996477
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran affects the expression of COL1A1 mRNA"	20702594
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FGF2 protein results in increased stability of and results in increased expression of COL1A1 protein]	16303940
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased stability of and results in decreased expression of COL1A1 mRNA	16303940
C081331	24-norursodeoxycholic acid	24-norursodeoxycholic acid results in decreased expression of COL1A1 mRNA	21115542
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of COL1A1 mRNA"	15215175
C109986	2-aminoethoxydiphenyl borate	2-aminoethoxydiphenyl borate inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of COL1A1 mRNA]	23958495
C109986	2-aminoethoxydiphenyl borate	2-aminoethoxydiphenyl borate inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of COL1A1 protein]	23958495
C109986	2-aminoethoxydiphenyl borate	2-aminoethoxydiphenyl borate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	25150141
C109986	2-aminoethoxydiphenyl borate	2-aminoethoxydiphenyl borate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	25150141
C518860	2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide	"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]"	26443840
C518860	2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide	"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]"	26443840
C577942	2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide	"2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]"	26644586
C577942	2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide	"2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide results in decreased expression of COL1A1 mRNA"	26644586
C502971	2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine	2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	15723089
C569355	2-quinoxaline-carboxamide-N-adamantan-1-yl	[2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of COL1A1 mRNA]	19781536
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl affects the expression of COL1A1 mRNA"	23994337
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL1A1 mRNA"	20959002
C000594958	3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide	"3,4,5-trihydroxy-N-(4-(thiazol-2-ylsulfamoyl)-phenyl)-benzamide results in decreased expression of COL1A1 mRNA"	26107568
C047368	3-methylquercetin	3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	27151496
C047368	3-methylquercetin	3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	27151496
C509927	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	16570917
C509927	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL1A1 mRNA]	16570917
C009505	4,4'-diaminodiphenylmethane	"4,4'-diaminodiphenylmethane results in increased expression of COL1A1 mRNA"	25380136
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of COL1A1 mRNA]	26053266
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C408690	4-cresol sulfate	4-cresol sulfate results in increased expression of COL1A1 mRNA	23325087
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased expression of COL1A1 mRNA	14672615
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased expression of COL1A1 protein	14672615
C030601	4-hydroxymercuribenzoate	4-hydroxymercuribenzoate inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12223100
C002202	4-oxoretinoic acid	4-oxoretinoic acid results in increased expression of COL1A1 mRNA	17034753
C041819	4-oxoretinol	4-oxoretinol results in increased expression of COL1A1 mRNA	17034753
C008500	5'-methylthioadenosine	5'-methylthioadenosine results in decreased expression of COL1A1 mRNA	15983038
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C120038	9,10-dihydroxy-12-octadecenoic acid	"9,10-dihydroxy-12-octadecenoic acid results in decreased expression of COL1A1 mRNA"	12021203
C051208	9,10-epoxy-12-octadecenoic acid	"9,10-epoxy-12-octadecenoic acid results in decreased expression of COL1A1 mRNA"	12021203
C099958	acanthoic acid	acanthoic acid inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	28964808
C099958	acanthoic acid	acanthoic acid inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	28964808
D000079	Acetaldehyde	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	Acetaldehyde results in increased expression of COL1A1 protein	17030193
D000079	Acetaldehyde	[Acetaldehyde results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein	17030193
D000079	Acetaldehyde	Imatinib Mesylate inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17030193
D000079	Acetaldehyde	Imatinib Mesylate inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	MAPK1 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	MAPK3 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	PPARG protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17030193
D000079	Acetaldehyde	PPARG protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	PRKCD protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	rottlerin inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17030193
D000079	Acetaldehyde	rottlerin inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000079	Acetaldehyde	Acetaldehyde affects the expression of COL1A1 mRNA	17949463
D000079	Acetaldehyde	Acetaldehyde promotes the reaction [ADIPOQ protein results in decreased expression of COL1A1 mRNA]	17949463
D000079	Acetaldehyde	Acetaldehyde promotes the reaction [CEBPB protein binds to COL1A1 enhancer]	10613735
D000079	Acetaldehyde	Acetaldehyde results in increased expression of COL1A1 mRNA	10069557\|8660697
D000079	Acetaldehyde	CAT protein inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	10613735
D000079	Acetaldehyde	Hydrogen Peroxide promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	10613735
D000079	Acetaldehyde	TGFB1 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	8660697
D000079	Acetaldehyde	4-hydroxymercuribenzoate inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12223100
D000079	Acetaldehyde	Acetaldehyde promotes the reaction [CEBPB protein binds to COL1A1 promoter]	10871045
D000079	Acetaldehyde	[Acetaldehyde promotes the reaction [CEBPB protein binds to COL1A1 promoter]] which results in increased expression of COL1A1 mRNA	10871045\|1087104
D000079	Acetaldehyde	Acetaldehyde results in increased expression of COL1A1 mRNA	10733585\|1206569
D000079	Acetaldehyde	IL6 protein affects the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17952619
D000079	Acetaldehyde	IL6 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12419648\|1795261
D000079	Acetaldehyde	KLF9 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	10733585
D000079	Acetaldehyde	Pentoxifylline inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12419648\|1795261
D000079	Acetaldehyde	SB 203580 inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12065697
D000079	Acetaldehyde	TGFB1 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12223100
D000079	Acetaldehyde	TGFBR2 protein promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12223100
D000079	Acetaldehyde	Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17952619
D000082	Acetaminophen	Acetaminophen results in decreased expression of COL1A1 mRNA	21420995
D000082	Acetaminophen	Acetaminophen results in increased expression of COL1A1 mRNA	28286204
D000082	Acetaminophen	[Clofibrate co-treated with Acetaminophen] affects the expression of COL1A1 mRNA	17585979
D000082	Acetaminophen	EGR1 protein affects the reaction [Acetaminophen results in increased expression of COL1A1 mRNA]	28286204
D000082	Acetaminophen	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of COL1A1 mRNA]	17585979
D019342	Acetic Acid	Acetic Acid results in decreased expression of COL1A1 protein	21296659
D000111	Acetylcysteine	Acetylcysteine results in decreased expression of COL1A1 mRNA	11710721
D000111	Acetylcysteine	Acetylcysteine results in decreased expression of COL1A1 mRNA	17602960
D000111	Acetylcysteine	Acetylcysteine results in decreased expression of COL1A1 protein	17602960
D000111	Acetylcysteine	Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 mRNA]	17602960
D000111	Acetylcysteine	Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 protein]	17602960
D020106	Acrylamide	Acrylamide results in decreased expression of COL1A1 mRNA	15749267
D012435	S-Adenosylhomocysteine	S-Adenosylhomocysteine results in decreased expression of COL1A1 mRNA	15983038
D012436	S-Adenosylmethionine	S-Adenosylmethionine inhibits the reaction [LEP protein results in increased expression of COL1A1 mRNA]	16996477
D012436	S-Adenosylmethionine	S-Adenosylmethionine results in decreased expression of COL1A1 mRNA	15983038
C031143	AICA ribonucleotide	AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27688165
D000447	Aldehydes	Aldehydes results in increased expression of COL1A1 mRNA	25014914
C103303	alitretinoin	alitretinoin results in increased expression of COL1A1 mRNA	17034753
C004471	allyl isothiocyanate	allyl isothiocyanate results in decreased expression of COL1A1 mRNA	24036144
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of COL1A1 mRNA	17898587
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [Canola Oil results in increased expression of COL1A1 mRNA]	8119541
C010845	aluminum chloride	aluminum chloride results in decreased expression of COL1A1 mRNA	26658030\|2772069
C010845	aluminum chloride	TGFB1 protein inhibits the reaction [aluminum chloride results in decreased expression of COL1A1 mRNA]	27720690
D000537	Aluminum Oxide	[Aluminum Oxide co-treated with Magnesium] results in increased expression of COL1A1 protein	12209937
D000499	Allylamine	Allylamine results in increased expression of COL1A1 mRNA	15910882
D017311	Amlodipine	Amlodipine results in decreased expression of COL1A1 mRNA	9449387
C053506	ammonium perchlorate	ammonium perchlorate results in increased expression of COL1A1 mRNA	20937628
C059765	amphotericin B, deoxycholate drug combination	"amphotericin B, deoxycholate drug combination results in increased expression of COL1A1 mRNA"	22863853
D000806	Angiotensin-Converting Enzyme Inhibitors	Angiotensin-Converting Enzyme Inhibitors results in decreased expression of COL1A1 mRNA	15667801
C004984	apocarotenal	apocarotenal results in decreased expression of COL1A1 mRNA	17034753
C519728	archazolid B	archazolid B results in decreased expression of COL1A1 mRNA	25218289
C031942	argatroban	argatroban inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA]	22841818
C006632	arsenic trioxide	arsenic trioxide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	24762191
C006632	arsenic trioxide	arsenic trioxide inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	24762191
C006632	arsenic trioxide	arsenic trioxide results in increased expression of COL1A1 protein	19364129
C006632	arsenic trioxide	arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	24762191
C006632	arsenic trioxide	arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	24762191
D017639	Asbestos, Amosite	"Asbestos, Amosite results in increased expression of COL1A1 mRNA"	11306436
D017639	Asbestos, Amosite	"benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D017639	Asbestos, Amosite	"Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D017639	Asbestos, Amosite	"Iron promotes the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D017639	Asbestos, Amosite	"tetramethylthiourea inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D017636	Asbestos, Amphibole	"Asbestos, Amphibole results in increased expression of COL1A1 mRNA"	19219932
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in decreased expression of COL1A1 mRNA"	18687144\|2363490
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of COL1A1 mRNA"	11250057
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased expression of COL1A1 mRNA"	18192500
D017638	Asbestos, Crocidolite	"MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of COL1A1 mRNA]"	18192500
C011669	ascorbate-2-phosphate	ascorbate-2-phosphate results in increased expression of COL1A1 mRNA	22066831
C011669	ascorbate-2-phosphate	ascorbate-2-phosphate results in increased expression of COL1A1 protein	22066831
D001205	Ascorbic Acid	[Ascorbic Acid co-treated with Ethanol] results in decreased expression of COL1A1 mRNA	22149461
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	24239723
D001205	Ascorbic Acid	Ascorbic Acid results in increased expression of COL1A1 mRNA	12510807\|2810541
D001205	Ascorbic Acid	Ascorbic Acid results in increased expression of COL1A1 mRNA	14566779
D001241	Aspirin	Aspirin inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]	22306536
D000069059	Atorvastatin Calcium	Atorvastatin Calcium results in increased expression of COL1A1 mRNA	17252541
D001280	Atrazine	Atrazine results in increased expression of COL1A1 mRNA	22378314
D001374	Azacitidine	Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	22841775
D001374	Azacitidine	Azacitidine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	22841775
D001379	Azathioprine	Azathioprine results in increased expression of COL1A1 mRNA	19192274
C020976	azelastine	azelastine results in decreased expression of COL1A1 mRNA	8919039
C547126	AZM551248	AZM551248 results in increased expression of COL1A1 mRNA	22323515
C030935	benz(a)anthracene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL1A1 mRNA	27858113
D001554	Benzene	[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of COL1A1 mRNA	17905399
C006703	benzo(b)fluoranthene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL1A1 mRNA	27858113
D019324	beta-Naphthoflavone	beta-Naphthoflavone affects the expression of COL1A1 mRNA	23994337
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in decreased expression of COL1A1 mRNA	15240111
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL1A1 mRNA	18164116\|2004503
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of COL1A1 mRNA	21632981\|2258169
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of COL1A1 mRNA	20106945
D001564	Benzo(a)pyrene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL1A1 mRNA	27858113
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of COL1A1 mRNA	15034205\|2156981
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of COL1A1 mRNA	21839799
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of COL1A1 mRNA"	20382639
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of COL1A1 mRNA"	19150397
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	"benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D001599	Berberine	Berberine results in increased expression of COL1A1 mRNA	26478571
D019207	beta Carotene	beta Carotene results in decreased expression of COL1A1 mRNA	17034753
D004958	Estradiol	Estradiol results in increased expression of COL1A1 mRNA	23094148
D004958	Estradiol	IGF1R mutant form inhibits the reaction [Estradiol results in increased expression of COL1A1 mRNA]	23094148
D004958	Estradiol	Estradiol results in increased expression of COL1A1 mRNA	15902152
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in decreased expression of COL1A1 mRNA	19693291
D004958	Estradiol	Estradiol results in increased expression of COL1A1 mRNA	19484750
D004958	Estradiol	Estradiol results in decreased degradation of COL1A1 protein	15979666
D004958	Estradiol	Estradiol results in decreased expression of COL1A1 protein	15917159
D001629	Bezafibrate	Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of COL1A1 mRNA]	18513333
D001629	Bezafibrate	Bezafibrate results in increased expression of COL1A1 mRNA	21499286
D001629	Bezafibrate	Bezafibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	18513333
C472777	bisperoxovanadium	[hesperetin analog co-treated with bisperoxovanadium analog] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27818223
C006780	bisphenol A	bisphenol A results in decreased expression of COL1A1 mRNA	25594700
C006780	bisphenol A	bisphenol A results in decreased expression of COL1A1 mRNA	27809950
C006780	bisphenol A	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of COL1A1 mRNA]	27025157
C006780	bisphenol A	bisphenol A affects the expression of COL1A1 mRNA	25181051
C006780	bisphenol A	[bisphenol A co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA	25112833
C006780	bisphenol A	[bisphenol A co-treated with Dietary Fats] results in increased expression of COL1A1 protein	25112833
C006780	bisphenol A	bisphenol A results in increased expression of COL1A1 mRNA	27025157
C006780	bisphenol A	fulvestrant inhibits the reaction [bisphenol A results in increased expression of COL1A1 mRNA]	27025157
C025703	bleomycetin	bleomycetin results in increased expression of COL1A1 mRNA	20937628
D001761	Bleomycin	MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	28726637
D001761	Bleomycin	arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	24762191
D001761	Bleomycin	arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	24762191
D001761	Bleomycin	Bleomycin results in increased expression of COL1A1 mRNA	12003776\|1460956
D001761	Bleomycin	Bleomycin results in increased expression of COL1A1 protein	24762191\|2830066
D001761	Bleomycin	CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	14609568
D001761	Bleomycin	Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	28300665
D001761	Bleomycin	Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	28300665
D001761	Bleomycin	Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	12003776
D001761	Bleomycin	Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	28300665
D001761	Bleomycin	Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	28300665
D001761	Bleomycin	rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	19147827
D001761	Bleomycin	S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	29033951
D001761	Bleomycin	Bleomycin results in decreased expression of COL1A1 protein	25933445
D001761	Bleomycin	Bleomycin results in increased expression of COL1A1 mRNA	17434272\|2609321
D001761	Bleomycin	Bleomycin results in increased expression of COL1A1 protein	17434272
D001761	Bleomycin	Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	17434272
D001761	Bleomycin	Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	17434272
D001761	Bleomycin	Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	17434272
D001761	Bleomycin	Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	17434272
D001761	Bleomycin	Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	26093215
D001761	Bleomycin	Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	26093215
D001895	Boron	Boron results in increased expression of COL1A1 mRNA	21625915
D000551	Ambroxol	Ambroxol affects the reaction [Paraquat results in increased expression of COL1A1 mRNA]	21921364
D001966	Bromine	Bromine affects the expression of COL1A1 mRNA	18790026
C099813	bromochloroacetic acid	bromochloroacetic acid results in decreased expression of COL1A1 protein	21296659
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 mRNA]	17602960
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 protein]	17602960
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 mRNA]	17602960
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 protein]	17602960
C018475	butyraldehyde	butyraldehyde results in increased expression of COL1A1 mRNA	26079696
D002104	Cadmium	Cadmium results in increased expression of COL1A1 mRNA	11750084
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of COL1A1 protein	24527689
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of COL1A1 mRNA	28341147
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of COL1A1 mRNA	24982889
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of COL1A1 mRNA	20478370
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of COL1A1 mRNA	15499971
D019256	Cadmium Chloride	zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of COL1A1 mRNA]	15499971
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of COL1A1 mRNA	25993096
D002110	Caffeine	"[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COL1A1 mRNA"	20230807
D002110	Caffeine	"Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of COL1A1 mRNA]"	20230807
D002110	Caffeine	Caffeine results in decreased expression of COL1A1 mRNA	24275088
D002122	Calcium Chloride	Calcium Chloride results in increased expression of COL1A1 mRNA	25824407
D002126	Calcium Hydroxide	Calcium Hydroxide results in increased expression of COL1A1 mRNA	22083529
C031293	calcium silicate	[Zinc binds to calcium silicate] which results in increased expression of COL1A1 mRNA	23483914
D000074262	Canola Oil	alpha-Tocopherol inhibits the reaction [Canola Oil results in increased expression of COL1A1 mRNA]	8119541
D000074262	Canola Oil	Canola Oil results in increased expression of COL1A1 mRNA	8119541
D000074262	Canola Oil	Cycloheximide inhibits the reaction [Canola Oil results in increased expression of COL1A1 mRNA]	8119541
D000074262	Canola Oil	Methylene Blue inhibits the reaction [Canola Oil results in increased expression of COL1A1 mRNA]	8119541
D002211	Capsaicin	Capsaicin results in increased expression of COL1A1 mRNA	20349343
D002220	Carbamazepine	Carbamazepine affects the expression of COL1A1 mRNA	25979313
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of COL1A1 mRNA	18207697
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of COL1A1 mRNA	17030193
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of COL1A1 protein	17030193
D002251	Carbon Tetrachloride	Pentoxifylline promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	18207697
D002251	Carbon Tetrachloride	"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]"	26443840
D002251	Carbon Tetrachloride	"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]"	26443840
D002251	Carbon Tetrachloride	Carbon Tetrachloride deficiency inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27396813
D002251	Carbon Tetrachloride	Carbon Tetrachloride deficiency inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	27396813
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of COL1A1 mRNA	17640975
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of COL1A1 mRNA	11481614\|1254077
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of COL1A1 protein	15056808\|2643521
D002251	Carbon Tetrachloride	CXCL1 protein promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	16118408
D002251	Carbon Tetrachloride	epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	20438794
D002251	Carbon Tetrachloride	F2R protein affects the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17962354
D002251	Carbon Tetrachloride	[GJB1 protein affects the susceptibility to Carbon Tetrachloride] which affects the expression of COL1A1 mRNA	27268753
D002251	Carbon Tetrachloride	HAS3 protein affects the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27042213
D002251	Carbon Tetrachloride	HIF1A protein affects the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	24639359
D002251	Carbon Tetrachloride	IL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	16539848
D002251	Carbon Tetrachloride	(+)-JQ1 compound inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	26644586
D002251	Carbon Tetrachloride	LEP protein promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	11481614
D002251	Carbon Tetrachloride	Ly-364947 promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	25566828
D002251	Carbon Tetrachloride	MGAT5 protein affects the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	23798564
D002251	Carbon Tetrachloride	NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]]	27477297
D002251	Carbon Tetrachloride	NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]]	27477297
D002251	Carbon Tetrachloride	NPLC 0393 inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	21151953
D002251	Carbon Tetrachloride	Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27601294
D002251	Carbon Tetrachloride	RDH13 protein promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27865848
D002251	Carbon Tetrachloride	Tetrachlorodibenzodioxin promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27693115
D002251	Carbon Tetrachloride	tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27477297
D002251	Carbon Tetrachloride	tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	27477297
D002251	Carbon Tetrachloride	VWF gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	28527913
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of COL1A1 mRNA	23262250
D002251	Carbon Tetrachloride	[Carbon Tetrachloride co-treated with Interleukin 1 Receptor Antagonist Protein] results in increased expression of COL1A1 mRNA	16762003
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of COL1A1 mRNA	12632512\|1586057
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of COL1A1 protein	18054572\|2395849
D002251	Carbon Tetrachloride	Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	16420518
D002251	Carbon Tetrachloride	Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	23146752
D002251	Carbon Tetrachloride	Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	18006644
D002251	Carbon Tetrachloride	Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17708605
D002251	Carbon Tetrachloride	Dalteparin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17166617
D002251	Carbon Tetrachloride	"Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]"	12632512
D002251	Carbon Tetrachloride	hesperetin analog inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27818223
D002251	Carbon Tetrachloride	KNG1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	18054572
D002251	Carbon Tetrachloride	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17157831
D002251	Carbon Tetrachloride	resveratrol inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A1 mRNA]	23262250
D002251	Carbon Tetrachloride	Sulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	15633128
D002330	Carmustine	COL1A1 mRNA affects the susceptibility to Carmustine	16365179
D002331	Carnitine	Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of COL1A1 mRNA]	28973641
D002331	Carnitine	Carnitine inhibits the reaction [sunitinib results in increased expression of COL1A1 mRNA]	26581635
C043211	carvedilol	carvedilol inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	22413959
C043211	carvedilol	carvedilol inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]	10722803\|1957528
C043211	carvedilol	"carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA]"	11682445
C043211	carvedilol	carvedilol results in decreased expression of COL1A1 mRNA	21216836
C043211	carvedilol	carvedilol results in decreased expression of COL1A1 protein	11181017
C024714	caryophyllene	caryophyllene inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	29097836
C054133	casticin	casticin results in decreased expression of COL1A1 mRNA	27862857
D000068579	Celecoxib	Celecoxib promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	16420518
D000068579	Celecoxib	Celecoxib results in decreased expression of COL1A1 mRNA	19201774
D002108	Ceruletide	Ceruletide results in increased expression of COL1A1 mRNA	25035110
D002108	Ceruletide	PTHLH protein modified form inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]	25035110
D002108	Ceruletide	PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]	25035110
D002108	Ceruletide	Ceruletide results in increased expression of COL1A1 mRNA	25035110
D002108	Ceruletide	PTHLH protein promotes the reaction [Ceruletide results in increased expression of COL1A1 mRNA]	25035110
D002108	Ceruletide	Ceruletide results in increased expression of COL1A1 mRNA	22280800
D002108	Ceruletide	PTHLH protein inhibits the reaction [Ceruletide results in increased expression of COL1A1 mRNA]	22280800
D002635	Chenodeoxycholic Acid	Chenodeoxycholic Acid results in decreased expression of COL1A1 mRNA	15980055
D002701	Chloramphenicol	Chloramphenicol results in increased expression of COL1A1 mRNA	22083529
D002726	Chlorogenic Acid	Chlorogenic Acid results in increased expression of COL1A1 mRNA	20706672
D002726	Chlorogenic Acid	Chlorogenic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	23146752
C023676	chloroquine diphosphate	chloroquine diphosphate results in increased expression of COL1A1 mRNA	19192274
D020355	Cholates	"[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA"	25814186
D020355	Cholates	"resveratrol inhibits the reaction [[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA]"	25814186
D002791	Cholesterol, Dietary	"[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA"	25814186
D002791	Cholesterol, Dietary	"resveratrol inhibits the reaction [[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA]"	25814186
D002794	Choline	Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of COL1A1 mRNA]	18513333
D002794	Choline	caryophyllene inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	29097836
D002794	Choline	CCL2 protein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	20697377
D002794	Choline	[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA	23439872
D002794	Choline	[Choline deficiency co-treated with Methionine deficiency] results in increased expression of COL1A1 mRNA	18513333
D002794	Choline	Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	19593819
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA	20548288\|2093899
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA	19593819\|2069737
D002794	Choline	NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]	19593819
D002794	Choline	pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	19593819
D002794	Choline	Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	22915297
C509369	chromic phosphate	chromic phosphate results in decreased expression of COL1A1 mRNA	11216681
C031180	chrysene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL1A1 mRNA	27858113
C475575	Cimicifuga extract BNO 1055	Cimicifuga extract BNO 1055 results in decreased expression of COL1A1 mRNA	15917159
D004002	Clodronic Acid	Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of COL1A1 mRNA]	27022031
D002994	Clofibrate	[Clofibrate co-treated with Acetaminophen] affects the expression of COL1A1 mRNA	17585979
D002994	Clofibrate	Clofibrate results in increased expression of COL1A1 mRNA	17585979
D002994	Clofibrate	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of COL1A1 mRNA]	17585979
D002995	Clofibric Acid	Clofibric Acid affects the expression of COL1A1 mRNA	17602206
C480342	clothianidin	clothianidin results in decreased expression of COL1A1 mRNA	29044138
D060729	Coal Ash	Coal Ash results in decreased expression of COL1A1 mRNA	19000753
C007095	cobaltiprotoporphyrin	cobaltiprotoporphyrin results in increased expression of COL1A1 mRNA	22155307
D003042	Cocaine	Cocaine results in increased expression of COL1A1 mRNA	9455993
C052387	cocoa butter	"[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA"	25814186
C052387	cocoa butter	"resveratrol inhibits the reaction [[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA]"	25814186
C024989	coenzyme Q10	coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of COL1A1 protein]	27087047
D003069	Coffee	Coffee results in decreased expression of COL1A1 mRNA	24275088
D065366	Cryptoxanthins	[Cryptoxanthins co-treated with Vitamin A] results in increased expression of COL1A1 mRNA	15962303
D065366	Cryptoxanthins	Cryptoxanthins results in increased expression of COL1A1 mRNA	15962303
D065366	Cryptoxanthins	Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA]	15962303
D065366	Cryptoxanthins	Dichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA]	15962303
C102326	cucurbitacin E	cucurbitacin E results in decreased expression of COL1A1 mRNA	27363783
D003471	Cuprizone	Cuprizone results in increased expression of COL1A1 mRNA	26577399
D003474	Curcumin	Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]	28700904
D003474	Curcumin	Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]	28700904
D003474	Curcumin	Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 mRNA]	17602960
D003474	Curcumin	Buthionine Sulfoximine inhibits the reaction [Curcumin results in decreased expression of COL1A1 protein]	17602960
D003474	Curcumin	Curcumin analog inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]	28700904
D003474	Curcumin	Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	17434272
D003474	Curcumin	Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	17434272
D003474	Curcumin	Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	18006644
D003474	Curcumin	Curcumin inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]	28700904
D003474	Curcumin	Curcumin inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	17355460
D003474	Curcumin	Curcumin results in decreased expression of COL1A1 mRNA	17531121\|1760296
D003474	Curcumin	Curcumin results in decreased expression of COL1A1 protein	17531121\|1760296
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA]	15962303
D003513	Cycloheximide	Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA]	17203194
D003513	Cycloheximide	Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA]	17203194
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Canola Oil results in increased expression of COL1A1 mRNA]	8119541
D016572	Cyclosporine	Cyclosporine results in decreased expression of COL1A1 mRNA	27989131
C072247	cyclo(Trp-Asp-Pro-Val-Leu)	cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of COL1A1 protein]	17391658
C072247	cyclo(Trp-Asp-Pro-Val-Leu)	EDN1 protein affects the reaction [cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of COL1A1 protein]]	17391658
D003538	Cystamine	Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17708605
D003545	Cysteine	Cysteine inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15158331
D003561	Cytarabine	Cytarabine results in decreased expression of COL1A1 mRNA	21198554
D015638	Cytochalasin D	Cytochalasin D inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]	23517783
D003609	Dactinomycin	Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]	18253093
D003609	Dactinomycin	Dactinomycin results in decreased expression of COL1A1 mRNA	11216681
D017985	Dalteparin	Dalteparin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17166617
D003630	Daunorubicin	Daunorubicin results in increased expression of COL1A1 mRNA	27816693
D003634	DDT	DDT results in increased expression of COL1A1 mRNA	22902829
C014347	decitabine	decitabine affects the expression of COL1A1 mRNA	23300844
C014347	decitabine	decitabine results in increased expression of COL1A1 mRNA	19424577
C014347	decitabine	decitabine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	24211420
C014347	decitabine	decitabine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	24211420
C014347	decitabine	decitabine results in decreased expression of COL1A1 mRNA	22056649
D003676	Deferoxamine	"Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D003907	Dexamethasone	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	26435214\|2680609
D003907	Dexamethasone	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	26435214\|2680609
D003907	Dexamethasone	Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	16430859
D003907	Dexamethasone	NLRC5 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	26806094
D003907	Dexamethasone	NLRC5 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]]	26806094
D003907	Dexamethasone	SIRT1 protein promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]]	26435214
D003907	Dexamethasone	Theophylline promotes the reaction [Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	16430859
D003907	Dexamethasone	Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	28300665
D003907	Dexamethasone	Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	28300665
D003907	Dexamethasone	[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27396813
D003907	Dexamethasone	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	26739621
D003907	Dexamethasone	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	26739621
D003907	Dexamethasone	Dexamethasone results in decreased expression of COL1A1 mRNA	14618091
D003907	Dexamethasone	PTPN1 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	26739621
D003907	Dexamethasone	PTPN1 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]]	26739621
C025292	diacetylrhein	diacetylrhein inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]	18321735
C025292	diacetylrhein	diacetylrhein results in decreased expression of COL1A1 mRNA	18321735
D003975	Diazepam	Diazepam results in increased expression of COL1A1 mRNA	19114084
D003994	Bucladesine	Bucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	11576339\|1643085
D002945	Cisplatin	Cisplatin affects the expression of COL1A1 mRNA	23300844
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in decreased expression of COL1A1 mRNA	27392435
D002945	Cisplatin	Cisplatin results in decreased expression of COL1A1 mRNA	27392435
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [Cryptoxanthins results in increased expression of COL1A1 mRNA]	15962303
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate affects the expression of COL1A1 mRNA	26924002
C027118	didecyldimethylammonium	didecyldimethylammonium results in increased expression of COL1A1 mRNA	19762220\|2353771
D004026	Dieldrin	Dieldrin results in decreased expression of COL1A1 protein	20584760
D004041	Dietary Fats	argatroban inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA]	22841818
D004041	Dietary Fats	Dietary Fats results in increased expression of COL1A1 mRNA	18042831\|2260994
D004041	Dietary Fats	FGF15 gene mutant form inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA]	28673684
D004041	Dietary Fats	[GPX4 gene mutant form results in increased susceptibility to [Dietary Fats co-treated with Dietary Sucrose]] which results in increased expression of COL1A1 mRNA	26042203
D004041	Dietary Fats	[bisphenol A co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA	25112833
D004041	Dietary Fats	[bisphenol A co-treated with Dietary Fats] results in increased expression of COL1A1 protein	25112833
D004041	Dietary Fats	"carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA]"	11682445
D004041	Dietary Fats	[Ethanol co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA	21051528
D004041	Dietary Fats	"[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA"	11682445
D004041	Dietary Fats	Dietary Fats results in increased expression of COL1A1 mRNA	21852083
D004041	Dietary Fats	resveratrol inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA]	21852083
D019422	Dietary Sucrose	[GPX4 gene mutant form results in increased susceptibility to [Dietary Fats co-treated with Dietary Sucrose]] which results in increased expression of COL1A1 mRNA	26042203
C014476	diethyl maleate	diethyl maleate results in decreased expression of COL1A1 mRNA	21161181
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL1A1 mRNA	18164116\|2004503
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of COL1A1 mRNA	25374375
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of COL1A1 promoter	25374375
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] affects the expression of COL1A1 mRNA	23830814
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA	28943392
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of COL1A1 mRNA	19638242
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of COL1A1 mRNA	16086434
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of COL1A1 protein	16086434
D002117	Calcitriol	Calcitriol results in increased expression of COL1A1 mRNA	16002434\|2810541
D002117	Calcitriol	Calcitriol results in increased expression of COL1A1 protein	17595320
D002117	Calcitriol	IGFBP5 protein inhibits the reaction [Calcitriol results in increased expression of COL1A1 protein]	17595320
D002117	Calcitriol	Calcitriol results in increased expression of COL1A1 mRNA	16813520
D002117	Calcitriol	Calcitriol results in increased expression of COL1A1 mRNA	16813520
D004110	Diltiazem	Diltiazem inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]	27095094
C552122	dimerumic acid	dimerumic acid results in decreased expression of COL1A1 mRNA	24036144
C552122	dimerumic acid	NFE2L2 protein affects the reaction [dimerumic acid results in decreased expression of COL1A1 mRNA]	24036144
C472511	dimethylarsinous acid	dimethylarsinous acid results in decreased expression of COL1A1 mRNA	16507463
C472511	dimethylarsinous acid	dimethylarsinous acid results in increased expression of COL1A1 mRNA	23876855
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of COL1A1 mRNA"	22485181
D004128	Dimethylnitrosamine	2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	15723089
D004128	Dimethylnitrosamine	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	16570917
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in increased expression of COL1A1 mRNA	15571005\|1572308
D004128	Dimethylnitrosamine	pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	15571005
D004128	Dimethylnitrosamine	[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	16169303
C024629	dimethyl phthalate	dimethyl phthalate affects the expression of COL1A1 mRNA	26924002
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]	11682029
D004147	Dioxins	Dioxins affects the expression of COL1A1 mRNA	20463971
D004176	Dipyridamole	Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	11576339
D004176	Dipyridamole	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	11576339
D004176	Dipyridamole	Dipyridamole results in decreased expression of COL1A1 mRNA	12271277\|7617123
D004237	Diuron	Diuron results in decreased expression of COL1A1 mRNA	25152437
D004237	Diuron	Diuron results in increased expression of COL1A1 mRNA	21551480
D016291	Dizocilpine Maleate	Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]	28987794
D016291	Dizocilpine Maleate	Dizocilpine Maleate results in increased expression of COL1A1 mRNA	28987794
D017292	Doxazosin	Doxazosin inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]	19575289
D004317	Doxorubicin	Doxorubicin results in increased expression of COL1A1 mRNA	15033991
D004317	Doxorubicin	[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of COL1A1 mRNA	21040762
D004317	Doxorubicin	coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of COL1A1 protein]	27087047
D004317	Doxorubicin	Doxorubicin results in increased expression of COL1A1 protein	27087047
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]"	18606216
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]"	12632512
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]"	17629604
D004642	Emodin	Emodin results in decreased expression of COL1A1 mRNA	15288473
D004656	Enalapril	Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	12003776
D004726	Endosulfan	Endosulfan results in decreased secretion of COL1A1 protein	16475185
D004726	Endosulfan	Endosulfan results in increased expression of COL1A1 mRNA	22902829
C034959	enterotoxin C, staphylococcal	"enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]"	26099602
C118739	entinostat	entinostat results in increased expression of COL1A1 mRNA	26272509
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C118739	entinostat	entinostat results in decreased expression of COL1A1 protein	26251326
C038939	enzacamene	enzacamene results in increased degradation of COL1A1 protein	15979666
C045651	epigallocatechin gallate	epigallocatechin gallate results in increased expression of COL1A1 mRNA	20706672
C045651	epigallocatechin gallate	epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	20438794
D000431	Ethanol	[Ascorbic Acid co-treated with Ethanol] results in decreased expression of COL1A1 mRNA	22149461
D000431	Ethanol	Ascorbic Acid inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	24239723
D000431	Ethanol	Ethanol results in increased expression of COL1A1 protein	24239723
D000431	Ethanol	Silymarin inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	24239723
D000431	Ethanol	acanthoic acid inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	28964808
D000431	Ethanol	acanthoic acid inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	28964808
D000431	Ethanol	CNR1 gene mutant form inhibits the reaction [[Ethanol co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA]	21863215
D000431	Ethanol	[Ethanol co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA	21863215
D000431	Ethanol	Ethanol results in increased expression of COL1A1 mRNA	19167417\|2896480
D000431	Ethanol	Ethanol results in increased expression of COL1A1 protein	27688165\|2783716
D000431	Ethanol	NFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]]	27837167
D000431	Ethanol	tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	27837167
D000431	Ethanol	[Thioacetamide co-treated with Ethanol] results in increased expression of COL1A1 protein	16780996
D000431	Ethanol	thymoquinone inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	27688165
D000431	Ethanol	carvedilol inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	22413959
D000431	Ethanol	[Ethanol co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA	21051528
D000431	Ethanol	Ethanol results in decreased expression of COL1A1 mRNA	17920746
D000431	Ethanol	Ethanol results in increased expression of COL1A1 mRNA	12065697\|2228080
D000431	Ethanol	fomepizole inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	9540844
D000431	Ethanol	PTHLH protein inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	22280800
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of COL1A1 mRNA	17555576
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of COL1A1 mRNA	17942748
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL1A1 mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of COL1A1 mRNA	12655037
C039614	ethylisopropylamiloride	ethylisopropylamiloride inhibits the reaction [ferric nitrilotriacetate results in increased expression of COL1A1 protein]	11159895
C039614	ethylisopropylamiloride	ethylisopropylamiloride inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of COL1A1 protein]	11159895
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in decreased expression of COL1A1 mRNA	23649840
D018690	Excitatory Amino Acid Agonists	Dizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]	28987794
D018690	Excitatory Amino Acid Agonists	Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA	28987794
D018690	Excitatory Amino Acid Agonists	Excitatory Amino Acid Antagonists inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]	28987794
D018690	Excitatory Amino Acid Agonists	U 0126 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]	28987794
D018691	Excitatory Amino Acid Antagonists	Excitatory Amino Acid Antagonists inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]	28987794
C063007	exoenzyme C3, Clostridium botulinum	"exoenzyme C3, Clostridium botulinum inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]"	21439370\|2351778
C049347	fasudil	fasudil results in decreased expression of COL1A1 mRNA	22465603
D011345	Fenofibrate	Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	19593819
D011345	Fenofibrate	NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	19593819
D011345	Fenofibrate	Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	19593819
D011345	Fenofibrate	Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	19593819
D011345	Fenofibrate	Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]	28871336
D011345	Fenofibrate	NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	19593819
D011345	Fenofibrate	NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]	19593819
C006012	fenofibric acid	fenofibric acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	18513333
C017690	fenvalerate	fenvalerate results in increased expression of COL1A1 mRNA	20230880
C013531	ferric ammonium citrate	ferric ammonium citrate results in decreased expression of COL1A1 mRNA	19735707
C020326	ferric nitrilotriacetate	ethylisopropylamiloride inhibits the reaction [ferric nitrilotriacetate results in increased expression of COL1A1 protein]	11159895
C020326	ferric nitrilotriacetate	ferric nitrilotriacetate results in increased expression of COL1A1 protein	11159895
D000068876	Fingolimod Hydrochloride	Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	24893116
D005459	Fluorides	Fluorides analog results in increased expression of COL1A1 mRNA	20634111
D005472	Fluorouracil	Fluorouracil results in decreased expression of COL1A1 protein	21296659
D005492	Folic Acid	[Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA	23439872
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA	20548288\|2093899
C010238	fomepizole	fomepizole inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]	9540844
D004397	Fonofos	Fonofos results in increased methylation of COL1A1 promoter	22847954
C070081	fulvestrant	fulvestrant inhibits the reaction [bisphenol A results in increased expression of COL1A1 mRNA]	27025157
C005023	fulvic acid	[fulvic acid co-treated with Selenium deficiency] affects the metabolism of COL1A1 protein	8435081
C039281	furan	furan results in increased expression of COL1A1 mRNA	27387713
D005688	Galactosamine	Galactosamine results in increased expression of COL1A1 mRNA	27876602
D005688	Galactosamine	Genistein inhibits the reaction [Galactosamine results in increased expression of COL1A1 mRNA]	27876602
D019833	Genistein	Genistein results in decreased expression of COL1A1 mRNA	22228119
D019833	Genistein	Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA]	17203194
D019833	Genistein	Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA]	17203194
D019833	Genistein	[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA	17203194
D019833	Genistein	[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA	17203194
D019833	Genistein	Genistein inhibits the reaction [Galactosamine results in increased expression of COL1A1 mRNA]	27876602
D019833	Genistein	Genistein inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	12580099
D019833	Genistein	Genistein results in decreased expression of COL1A1 mRNA	11749858
C002963	geranylgeranyl pyrophosphate	geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA]	16575855
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in increased expression of COL1A1 mRNA	19356626
D005944	Glucosamine	Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]	18321735
D005944	Glucosamine	Glucosamine results in decreased expression of COL1A1 mRNA	18321735
D005947	Glucose	DKK1 protein inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]	29163160
D005947	Glucose	Glucose deficiency affects the secretion of COL1A1 protein	24802182
D005947	Glucose	Glucose results in increased expression of COL1A1 mRNA	29163160
D005947	Glucose	Curcumin analog inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]	28700904
D005947	Glucose	Curcumin inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]	28700904
D005947	Glucose	Glucose results in increased expression of COL1A1 mRNA	28700904
D006037	Glyoxal	Glyoxal results in decreased expression of COL1A1 mRNA	28760545
D006046	Gold	Gold analog results in increased expression of COL1A1 protein	24780912
D006052	Gold Sodium Thiomalate	Gold Sodium Thiomalate results in increased expression of COL1A1 mRNA	19192274
D056604	Grape Seed Extract	Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	28300665
D056604	Grape Seed Extract	Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	28300665
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	22863721
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]	22863721
D006118	Griseofulvin	Griseofulvin results in increased expression of COL1A1 mRNA	12735108
C568713	GSK1210151A	GSK1210151A inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	26644586
C568713	GSK1210151A	GSK1210151A results in decreased expression of COL1A1 mRNA	26644586
C004451	guaiazulene	guaiazulene results in decreased expression of COL1A1 mRNA	20854889
C004451	guaiazulene	guaiazulene results in decreased expression of COL1A1 protein	20854889
C119543	GW0072	GW0072 results in decreased expression of COL1A1 mRNA	12021203
C412815	GW 4064	GW 4064 results in decreased expression of COL1A1 mRNA	15980055
C010176	halofuginone	halofuginone results in decreased expression of COL1A1 mRNA	18458672
C010176	halofuginone	halofuginone inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	11172339\|1217562
C010176	halofuginone	halofuginone inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]	12175628\|1473909
C010176	halofuginone	halofuginone results in decreased expression of COL1A1 mRNA	16489207
C010176	halofuginone	halofuginone results in increased expression of COL1A1 mRNA	17180598
D006533	Heptachlor	Heptachlor results in increased expression of COL1A1 mRNA	22902829
C013015	hesperetin	[hesperetin analog co-treated with bisperoxovanadium analog] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27818223
C013015	hesperetin	hesperetin analog inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27818223
C013015	hesperetin	hesperetin analog inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	27818223
C013015	hesperetin	hesperetin analog inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27818223
C001335	hexachlorobutadiene	hexachlorobutadiene affects the expression of COL1A1 mRNA	21905055
C001335	hexachlorobutadiene	hexachlorobutadiene results in decreased expression of COL1A1 mRNA	21905055
C005499	honokiol	honokiol affects the expression of COL1A1 mRNA	21265825
C005499	honokiol	honokiol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	21265825
D017313	Fenretinide	Fenretinide results in decreased expression of COL1A1 mRNA	28973697
D006830	Hydralazine	[Hydralazine co-treated with Valproic Acid] results in increased expression of COL1A1 mRNA	17183730
D006830	Hydralazine	Hydralazine results in decreased expression of COL1A1 mRNA	8941590
D006854	Hydrocortisone	Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	17434272
D006854	Hydrocortisone	Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]	17434272
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of COL1A1 mRNA	25130202
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of COL1A1 mRNA	22083529
D006861	Hydrogen Peroxide	myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA]	25130202
D006861	Hydrogen Peroxide	Hydrogen Peroxide promotes the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	10613735
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in decreased expression of COL1A1 mRNA	25130202
D006861	Hydrogen Peroxide	myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA]	25130202
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of COL1A1 mRNA	23022513
D006861	Hydrogen Peroxide	tetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of COL1A1 mRNA]	23022513
C031927	hydroquinone	hydroquinone results in increased expression of COL1A1 protein	18055817
C031927	hydroquinone	MMP14 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]	18055817
C031927	hydroquinone	[TIMP2 protein co-treated with MMP14 protein] inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]	18055817
C031927	hydroquinone	TIMP2 protein inhibits the reaction [hydroquinone results in increased expression of COL1A1 protein]	18055817
C005044	hydroxyethyl methacrylate	hydroxyethyl methacrylate results in decreased expression of COL1A1 mRNA	20668299
C005044	hydroxyethyl methacrylate	hydroxyethyl methacrylate results in decreased expression of COL1A1 protein	20668299
C495366	hydroxyoctadecadienoic acid	hydroxyoctadecadienoic acid results in decreased expression of COL1A1 mRNA	12021203
D000068877	Imatinib Mesylate	Imatinib Mesylate inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17030193
D000068877	Imatinib Mesylate	Imatinib Mesylate inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D000068877	Imatinib Mesylate	Imatinib Mesylate results in decreased expression of COL1A1 mRNA	24321339
C078038	inchinko-to	inchinko-to results in decreased expression of COL1A1 mRNA	15288473
C016517	indole-3-carbinol	indole-3-carbinol affects the expression of COL1A1 mRNA	21396975
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole affects the expression of COL1A1 mRNA"	23994337
D007213	Indomethacin	Indomethacin inhibits the reaction [IL1B protein results in decreased expression of COL1A1 mRNA]	8971655
D053590	Interleukin 1 Receptor Antagonist Protein	[Carbon Tetrachloride co-treated with Interleukin 1 Receptor Antagonist Protein] results in increased expression of COL1A1 mRNA	16762003
D007455	Iodine	Iodine results in increased expression of COL1A1 mRNA	22083529
D015759	Ionomycin	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL1A1 mRNA	25613284
D007501	Iron	"Iron promotes the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
D007505	Iron-Dextran Complex	Diltiazem inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]	27095094
D007505	Iron-Dextran Complex	Iron-Dextran Complex results in increased expression of COL1A1 protein	27095094
D007505	Iron-Dextran Complex	Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]	27095094
D007505	Iron-Dextran Complex	Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]	27095094
C051140	iron(II)-ascorbic acid complex	ethylisopropylamiloride inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of COL1A1 protein]	11159895
C051140	iron(II)-ascorbic acid complex	iron(II)-ascorbic acid complex results in increased expression of COL1A1 protein	11159895
D015056	1-Methyl-3-isobutylxanthine	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	26435214\|2680609
D015056	1-Methyl-3-isobutylxanthine	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	26435214\|2680609
D015056	1-Methyl-3-isobutylxanthine	NLRC5 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	26806094
D015056	1-Methyl-3-isobutylxanthine	NLRC5 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]]	26806094
D015056	1-Methyl-3-isobutylxanthine	SIRT1 protein promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]]	26435214
D015056	1-Methyl-3-isobutylxanthine	[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27396813
D015056	1-Methyl-3-isobutylxanthine	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	26739621
D015056	1-Methyl-3-isobutylxanthine	[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	26739621
D015056	1-Methyl-3-isobutylxanthine	PTPN1 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	26739621
D015056	1-Methyl-3-isobutylxanthine	PTPN1 protein inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]]	26739621
D007529	Isoflavones	Isoflavones affects the expression of COL1A1 mRNA	16365062
D007545	Isoproterenol	Isoproterenol results in increased expression of COL1A1 mRNA	24945829\|2852631
D007545	Isoproterenol	Isoproterenol results in increased expression of COL1A1 protein	28526319
D007545	Isoproterenol	manidipine inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]	9559417
C585534	IWR-1 compound	[IWR-1 compound results in decreased activity of CTNNB1 protein] which results in decreased expression of COL1A1 mRNA	27477297
C585534	IWR-1 compound	[IWR-1 compound results in decreased activity of CTNNB1 protein] which results in decreased expression of COL1A1 protein	27477297
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in decreased expression of COL1A1 mRNA	27392435
C544151	jinfukang	jinfukang results in increased expression of COL1A1 mRNA	27392435
C098607	JP8 aviation fuel	JP8 aviation fuel results in decreased expression of COL1A1 mRNA	15618438
C561695	(+)-JQ1 compound	(+)-JQ1 compound inhibits the reaction [BRD4 protein binds to COL1A1 enhancer]	26644586
C561695	(+)-JQ1 compound	(+)-JQ1 compound inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	26644586
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of COL1A1 mRNA	26644586\|2675264
C561695	(+)-JQ1 compound	(+)-JQ1 compound inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	26644586
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of COL1A1 mRNA	26644586
D007608	Kainic Acid	Kainic Acid results in increased expression of COL1A1 mRNA	17997037
D007840	Latex	Latex analog results in decreased expression of COL1A1 mRNA	24768652
D007854	Lead	Lead results in decreased expression of COL1A1 mRNA	23086611
C008261	lead acetate	lead acetate results in decreased expression of COL1A1 mRNA	11578147
C008261	lead acetate	lead acetate results in increased expression of COL1A1 mRNA	22641619
C000589733	leukadherin-1	FGG protein affects the reaction [leukadherin-1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]]	26921287
C000589733	leukadherin-1	leukadherin-1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	26921287
C039294	linoleylanilide	linoleylanilide results in increased expression of COL1A1 mRNA	8119541
C482199	lipopolysaccharide, E coli O55-B5	"lipopolysaccharide, E coli O55-B5 results in increased expression of COL1A1 mRNA"	24972896
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of COL1A1 mRNA	23585870
D008070	Lipopolysaccharides	Losartan inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A1 mRNA]	23585870
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of COL1A1 mRNA	17965732
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of COL1A1 protein	17965732
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of COL1A1 mRNA	16436656
D019808	Losartan	Losartan inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A1 mRNA]	23585870
D019808	Losartan	Losartan results in decreased expression of COL1A1 mRNA	18300870
D019808	Losartan	Losartan results in decreased expression of COL1A1 mRNA	15100363
D019808	Losartan	Losartan inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]	22306536
C520284	Ly-364947	Ly-364947 promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	25566828
D008274	Magnesium	[Aluminum Oxide co-treated with Magnesium] results in increased expression of COL1A1 protein	12209937
D008315	Malondialdehyde	Malondialdehyde results in decreased expression of COL1A1 mRNA	28760545
C013592	mangiferin	mangiferin inhibits the reaction [AGT protein results in increased expression of COL1A1 mRNA]	19706694
C054218	manidipine	manidipine inhibits the reaction [Isoproterenol results in increased expression of COL1A1 mRNA]	9559417
C093896	marinobufagenin	marinobufagenin results in increased expression of COL1A1 mRNA	26702050
D015122	Mercaptopurine	Mercaptopurine results in decreased expression of COL1A1 mRNA	23358152
C042720	mercuric bromide	mercuric bromide results in increased expression of COL1A1 mRNA	26272509
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of COL1A1 mRNA	16507785
D008715	Methionine	Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of COL1A1 mRNA]	18513333
D008715	Methionine	caryophyllene inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	29097836
D008715	Methionine	CCL2 protein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	20697377
D008715	Methionine	[Choline deficiency co-treated with Methionine deficiency] results in increased expression of COL1A1 mRNA	18513333
D008715	Methionine	Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	19593819
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL1A1 mRNA	20548288\|2093899
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA	19593819\|2069737
D008715	Methionine	NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]	19593819
D008715	Methionine	pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	19593819
D008715	Methionine	Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	22915297
D008715	Methionine	Methionine inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15158331
D008727	Methotrexate	Methotrexate results in decreased expression of COL1A1 mRNA	17379860
D008727	Methotrexate	Methotrexate results in increased expression of COL1A1 mRNA	19192274\|2760541
D008751	Methylene Blue	Methylene Blue inhibits the reaction [Canola Oil results in increased expression of COL1A1 mRNA]	8119541
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of COL1A1 mRNA	23179753\|2627250
C004925	methylmercuric chloride	"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C030957	methylmercury II	[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of COL1A1 mRNA	17905399
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of COL1A1 mRNA	23649840
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of COL1A1 mRNA"	20188158
D015632	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of COL1A1 mRNA"	20230807
D015632	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	"[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COL1A1 mRNA"	20230807
D015632	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	"Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of COL1A1 mRNA]"	20230807
D015632	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COL1A1 mRNA"	20230807
D015632	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of COL1A1 mRNA]"	20230807
D008775	Methylprednisolone	Methylprednisolone results in increased expression of COL1A1 mRNA	19192274
D008775	Methylprednisolone	Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	26093215
D008790	Metoprolol	Metoprolol results in increased expression of COL1A1 mRNA	22888001
D008790	Metoprolol	Metoprolol results in increased expression of COL1A1 mRNA	22888001
D008798	Mevalonic Acid	Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA]	16575855
D015735	Mifepristone	Mifepristone results in decreased expression of COL1A1 mRNA	25972201
C086631	mineral trioxide aggregate	mineral trioxide aggregate results in decreased expression of COL1A1 mRNA	15810969
C540575	MK2i peptide	[TGFB1 protein co-treated with MK2i peptide] results in decreased expression of COL1A1 protein	20864298
C406082	monomethylarsonous acid	monomethylarsonous acid results in decreased expression of COL1A1 mRNA	16507463
C517284	monomethyl phthalate	monomethyl phthalate affects the expression of COL1A1 mRNA	26924002
C008577	myricitrin	myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA]	25130202
C008577	myricitrin	myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA]	25130202
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	11576339
C028473	N-acetyl-4-benzoquinoneimine	N-acetyl-4-benzoquinoneimine results in increased expression of COL1A1 mRNA	28286204
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of COL1A1 mRNA"	23634900
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog affects the expression of COL1A1 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of COL1A1 mRNA"	25620056
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of COL1A1 mRNA"	25510677\|2555468
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of COL1A1 protein"	25510677
C031721	naphthalene	naphthalene results in increased expression of COL1A1 mRNA	18978301
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA	21037076\|2463342
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of COL1A1 protein	22094456
D015058	1-Naphthylisothiocyanate	FGG protein affects the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	26921287
D015058	1-Naphthylisothiocyanate	FGG protein affects the reaction [leukadherin-1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]]	26921287
D015058	1-Naphthylisothiocyanate	IFNG protein affects the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	26921287
D015058	1-Naphthylisothiocyanate	leukadherin-1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	26921287
D015058	1-Naphthylisothiocyanate	RAG1 gene mutant form inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	28049044
D015058	1-Naphthylisothiocyanate	TGFB1 protein promotes the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	21037076
D015058	1-Naphthylisothiocyanate	Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	24633426
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA	25380136
C005274	naringin	naringin results in increased expression of COL1A1 mRNA	21741227
C017096	n-butoxyethanol	n-butoxyethanol results in decreased expression of COL1A1 mRNA	19812364
C553460	neoeriocitrin	neoeriocitrin inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of COL1A1 mRNA]	21741227
C553460	neoeriocitrin	neoeriocitrin results in increased expression of COL1A1 mRNA	21741227
D009532	Nickel	[2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased expression of COL1A1 mRNA]	19781536
D009532	Nickel	Nickel results in increased expression of COL1A1 mRNA	19781536
C029938	nickel sulfate	nickel sulfate results in decreased expression of COL1A1 mRNA	16166746
D009538	Nicotine	"[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COL1A1 mRNA"	20230807
D009538	Nicotine	"Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of COL1A1 mRNA]"	20230807
D009553	Nimodipine	Nimodipine inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]	27095094
C007350	nitrofen	nitrofen results in decreased expression of COL1A1 mRNA	11329586
C007350	nitrofen	nitrofen results in increased expression of COL1A1 mRNA	10359170
C002741	N-nitrosomorpholine	N-nitrosomorpholine results in increased expression of COL1A1 protein	19716841
C044387	N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine	"[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA"	19913120
D009638	Norepinephrine	carvedilol inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]	10722803\|1957528
D009638	Norepinephrine	Doxazosin inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]	19575289
D009638	Norepinephrine	Norepinephrine results in increased expression of COL1A1 mRNA	10722803\|1457759
D016912	Levonorgestrel	[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of COL1A1 mRNA	19074003
C559056	NPLC 0393	NPLC 0393 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	21151953
C559056	NPLC 0393	NPLC 0393 results in decreased expression of COL1A1 mRNA	21151953
C559056	NPLC 0393	PPP2CA protein affects the reaction [NPLC 0393 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	21151953
C559056	NPLC 0393	PPP2CA protein affects the reaction [NPLC 0393 results in decreased expression of COL1A1 mRNA]	21151953
C559056	NPLC 0393	NPLC 0393 inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	21151953
C559056	NPLC 0393	NPLC 0393 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	21151953
C559056	NPLC 0393	NPLC 0393 results in decreased expression of COL1A1 mRNA	21151953
C464660	obeticholic acid	obeticholic acid results in decreased expression of COL1A1 mRNA	27939613
C464660	obeticholic acid	obeticholic acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	15980055
C464660	obeticholic acid	obeticholic acid results in decreased expression of COL1A1 mRNA	15980055
C464660	obeticholic acid	obeticholic acid results in decreased expression of COL1A1 protein	15860571
D019787	Linoleic Acid	Linoleic Acid results in increased expression of COL1A1 mRNA	26240151
D019301	Oleic Acid	[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA	26187275
D015242	Ofloxacin	Ofloxacin results in decreased expression of COL1A1 protein	21903125
D019319	Okadaic Acid	Okadaic Acid results in increased expression of COL1A1 mRNA	8997264
C076029	olanzapine	olanzapine results in decreased phosphorylation of COL1A1 protein	25821032
D009828	Oleanolic Acid	Oleanolic Acid analog results in decreased expression of COL1A1 mRNA	17922224
C038731	oleoylanilide	oleoylanilide results in increased expression of COL1A1 mRNA	8119541
C029407	oleylamide	oleylamide results in decreased secretion of COL1A1 protein	16475185
C029407	oleylamide	oleylamide results in decreased secretion of COL1A1 protein	16475185
D000068557	Olmesartan Medoxomil	Olmesartan Medoxomil results in decreased expression of COL1A1 mRNA	18501344
C485800	osajin	osajin results in increased expression of COL1A1 mRNA	20706672
D010047	Ovalbumin	[Ovalbumin affects the susceptibility to Particulate Matter] which results in increased expression of COL1A1 mRNA	19176365
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of COL1A1 mRNA	25729387
C030110	oxaliplatin	oxaliplatin results in increased expression of COL1A1 mRNA	25729387
D010100	Oxygen	Cytochalasin D inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]	23517783
D010100	Oxygen	"exoenzyme C3, Clostridium botulinum inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]"	21439370\|2351778
D010100	Oxygen	HIF1A protein affects the reaction [Oxygen deficiency results in increased secretion of COL1A1 protein]	23423382
D010100	Oxygen	Oxygen deficiency results in increased expression of COL1A1 mRNA	24236059
D010100	Oxygen	Oxygen deficiency results in increased secretion of COL1A1 protein	23423382
D010100	Oxygen	Oxygen results in increased expression of COL1A1 mRNA	21439370\|2351778
D010100	Oxygen	RHOA protein affects the reaction [Oxygen results in increased expression of COL1A1 mRNA]	23517783
D010100	Oxygen	Y 27632 inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]	21439370\|2351778
D010100	Oxygen	Oxygen deficiency results in increased expression of COL1A1 mRNA	24205000
D010100	Oxygen	Oxygen results in increased expression of COL1A1 mRNA	21439370\|2236362
D010100	Oxygen	Y 27632 inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]	21439370
D010100	Oxygen	Oxygen deficiency results in increased expression of COL1A1 mRNA	11981751
D010100	Oxygen	Oxygen deficiency results in increased expression of COL1A1 protein	11981751
D010100	Oxygen	[Paraquat co-treated with Oxygen] results in increased expression of COL1A1 mRNA	12882763
D010126	Ozone	Ozone results in increased expression of COL1A1 mRNA	9820643
D010126	Ozone	Ozone results in increased expression of COL1A1 mRNA	16716893\|8018336
D017239	Paclitaxel	Paclitaxel results in increased expression of COL1A1 mRNA	19682730
D019308	Palmitic Acid	[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA	26187275
D000073878	Palm Oil	Palm Oil results in increased expression of COL1A1 mRNA	18042831
C019248	pamidronate	pamidronate results in decreased expression of COL1A1 mRNA	19597852
C019248	pamidronate	pamidronate results in decreased expression of COL1A1 protein	19597852
C496932	panobinostat	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
D010269	Paraquat	Paraquat results in increased expression of COL1A1 mRNA	20035857
D010269	Paraquat	Saralasin inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	20035857
D010269	Paraquat	"enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]"	26099602
D010269	Paraquat	Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	24893116
D010269	Paraquat	Paraquat results in increased expression of COL1A1 mRNA	17215068\|1996905
D010269	Paraquat	pirfenidone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	29273418
D010269	Paraquat	thymoquinone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	27375216
D010269	Paraquat	Ambroxol affects the reaction [Paraquat results in increased expression of COL1A1 mRNA]	21921364
D010269	Paraquat	[Paraquat co-treated with Oxygen] results in increased expression of COL1A1 mRNA	12882763
D010269	Paraquat	Paraquat results in increased expression of COL1A1 mRNA	21921364\|2587330
D010269	Paraquat	Paraquat results in increased expression of COL1A1 protein	26221080
D010269	Paraquat	Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	26221080
D010269	Paraquat	Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 protein]	26221080
D010278	Parathion	Parathion results in increased methylation of COL1A1 promoter	22847954
C084656	paricalcitol	[Phosphorus co-treated with paricalcitol] results in increased expression of COL1A1 mRNA	17715259
D052638	Particulate Matter	Particulate Matter results in decreased expression of COL1A1 mRNA	11216681
D052638	Particulate Matter	[Ovalbumin affects the susceptibility to Particulate Matter] which results in increased expression of COL1A1 mRNA	19176365
D052638	Particulate Matter	Particulate Matter results in increased expression of COL1A1 mRNA	12649123
D052638	Particulate Matter	SN50 peptide inhibits the reaction [Particulate Matter results in increased expression of COL1A1 mRNA]	12649123
C046012	pentanal	pentanal results in increased expression of COL1A1 mRNA	26079696
D010431	Pentoxifylline	Pentoxifylline promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	18207697
D010431	Pentoxifylline	Pentoxifylline inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12419648\|1795261
D010431	Pentoxifylline	Pentoxifylline results in decreased expression of COL1A1 mRNA	11788567\|1499349
C076994	perfluorooctane sulfonic acid	Carnitine inhibits the reaction [perfluorooctane sulfonic acid results in increased expression of COL1A1 mRNA]	28973641
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in increased expression of COL1A1 mRNA	28973641
D010578	Petroleum	Petroleum affects the expression of COL1A1 mRNA	25208076
D015232	Dinoprostone	Dinoprostone results in decreased expression of COL1A1 mRNA	8971655
D010634	Phenobarbital	[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of COL1A1 mRNA	25374375
D010634	Phenobarbital	[Diethylnitrosamine co-treated with Phenobarbital] results in increased methylation of COL1A1 promoter	25374375
D010634	Phenobarbital	Phenobarbital results in increased expression of COL1A1 mRNA	19162173
D019800	Phenol	Phenol results in increased expression of COL1A1 mRNA	22083529
D010662	Phenylmercuric Acetate	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
D010662	Phenylmercuric Acetate	Phenylmercuric Acetate results in increased expression of COL1A1 mRNA	26272509
D010672	Phenytoin	Phenytoin inhibits the reaction [IL1B protein results in decreased expression of COL1A1 mRNA]	8971655
D010672	Phenytoin	Phenytoin results in decreased expression of COL1A1 mRNA	8971655
D010672	Phenytoin	Phenytoin results in increased expression of COL1A1 mRNA	14741686
D010710	Phosphates	Phosphates results in decreased expression of COL1A1 mRNA	26111760
D010713	Phosphatidylcholines	[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	16169303
D010758	Phosphorus	[Phosphorus co-treated with paricalcitol] results in increased expression of COL1A1 mRNA	17715259
D064209	Phytochemicals	Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	26093215
C004479	pimagedine	pimagedine results in increased expression of COL1A1 mRNA	18380797
C093844	pirfenidone	pirfenidone results in decreased expression of COL1A1 mRNA	27235791
C093844	pirfenidone	pirfenidone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	29273418
C093844	pirfenidone	pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	15571005
C006253	pirinixic acid	pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	19593819
C006253	pirinixic acid	pirinixic acid results in decreased expression of COL1A1 mRNA	17426115
C006253	pirinixic acid	pirinixic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15474484
D010894	Piroxicam	Piroxicam results in increased expression of COL1A1 mRNA	19192274
D010936	Plant Extracts	Plant Extracts results in decreased expression of COL1A1 mRNA	23557933
D010936	Plant Extracts	Plant Extracts inhibits the reaction [AGT protein results in increased expression of COL1A1 mRNA]	19706694
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	17157831
D020959	Polyethylene	Polyethylene results in decreased expression of COL1A1 mRNA	11216681
C060540	polyhexamethyleneguanidine	polyhexamethyleneguanidine results in increased expression of COL1A1 mRNA	27989595
D011137	Polystyrenes	Polystyrenes results in decreased expression of COL1A1 mRNA	11216681
C474837	pomiferin	pomiferin results in increased expression of COL1A1 mRNA	20706672
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of COL1A1 protein	23718831
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of COL1A1 mRNA	23608068
D011239	Prednisolone	Prednisolone results in increased expression of COL1A1 mRNA	19192274
D011374	Progesterone	Progesterone results in decreased expression of COL1A1 mRNA	23012394
D011374	Progesterone	Progesterone results in decreased expression of COL1A1 mRNA	18070364
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in decreased expression of COL1A1 mRNA	19693291
D011374	Progesterone	Progesterone affects the expression of COL1A1 mRNA	17251523
C005556	propionaldehyde	propionaldehyde results in increased expression of COL1A1 mRNA	26079696
D011429	Propolis	Propolis results in increased expression of COL1A1 mRNA	20706672
D011441	Propylthiouracil	Propylthiouracil results in decreased expression of COL1A1 mRNA	24780913
C043680	ptaquiloside	[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of COL1A1 mRNA	23274088
C043680	ptaquiloside	ptaquiloside results in decreased expression of COL1A1 mRNA	23274088
D011692	Puromycin Aminonucleoside	4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of COL1A1 mRNA]	16570917
D011692	Puromycin Aminonucleoside	Puromycin Aminonucleoside results in increased expression of COL1A1 mRNA	16570917\|9527400
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of COL1A1 mRNA	27029645
C014175	pyrazolo(3,4-d)pyrimidine	"pyrazolo(3,4-d)pyrimidine analog affects the expression of COL1A1 mRNA"	21152443
D011748	Pyrogallol	Pyrogallol results in increased expression of COL1A1 mRNA	20362636
C020972	pyrrolidine dithiocarbamic acid	pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15078482
C528580	qishen yiqi	qishen yiqi inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	27636716
C528580	qishen yiqi	qishen yiqi inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27636716
D011791	Quartz	Quartz results in decreased expression of COL1A1 mRNA	27381660
D011794	Quercetin	Quercetin inhibits the reaction [DEFA1 protein results in increased expression of COL1A1 mRNA]	19814765
D011794	Quercetin	Quercetin inhibits the reaction [DEFA1 protein results in increased secretion of COL1A1 protein]	19814765
D011794	Quercetin	Quercetin inhibits the reaction [DEFA2 protein results in increased expression of COL1A1 mRNA]	19814765
D011794	Quercetin	Quercetin inhibits the reaction [DEFA2 protein results in increased secretion of COL1A1 protein]	19814765
D011794	Quercetin	Quercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	21216973\|2287183
D011794	Quercetin	Quercetin results in decreased expression of COL1A1 mRNA	22871832
D011794	Quercetin	Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27601294
D011794	Quercetin	Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]	22915297
D011794	Quercetin	Quercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	21216973
D011794	Quercetin	tin protoporphyrin IX inhibits the reaction [Quercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	21216973
D011794	Quercetin	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of COL1A1 mRNA]	26053266
D011794	Quercetin	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of COL1A1 mRNA]	26053266
D011794	Quercetin	Quercetin analog inhibits the reaction [sodium arsenite results in increased expression of COL1A1 mRNA]	20371363
D011794	Quercetin	Quercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	12580099
D011794	Quercetin	Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA]	23117658
D011794	Quercetin	Quercetin inhibits the reaction [Warfarin results in increased expression of COL1A1 mRNA]	23223575
D011794	Quercetin	Quercetin results in decreased expression of COL1A1 mRNA	11749858\|2760129
D011794	Quercetin	Quercetin results in increased expression of COL1A1 mRNA	26053266
D017257	Ramipril	Ramipril results in decreased expression of COL1A1 mRNA	11851355
C052785	rebamipide	rebamipide results in increased expression of COL1A1 mRNA	18299717
C059514	resveratrol	Niacinamide inhibits the reaction [resveratrol inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]]	25707573
C059514	resveratrol	resveratrol affects the secretion of COL1A1 protein	24802182
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein promotes the reaction [PTPN11 protein binds to BTK protein]]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein promotes the reaction [PTPN11 protein binds to SYK protein]]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein promotes the reaction [PTPN11 protein binds to VAV1 protein]]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein results in increased oxidation of and results in decreased activity of PTPN11 protein]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein results in increased phosphorylation of BTK protein]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein results in increased phosphorylation of NCF1 protein]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein results in increased phosphorylation of PLCG2 protein]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein results in increased phosphorylation of SYK protein]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [COL1A1 protein results in increased phosphorylation of VAV1 protein]	26482867
C059514	resveratrol	resveratrol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	27345520
C059514	resveratrol	resveratrol inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]	25707573
C059514	resveratrol	resveratrol results in decreased expression of COL1A1 mRNA	23815229\|2431705
C059514	resveratrol	resveratrol results in decreased expression of COL1A1 protein	26934322
C059514	resveratrol	resveratrol results in increased expression of COL1A1 mRNA	19167446
C059514	resveratrol	resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of COL1A1 mRNA]	23297412
C059514	resveratrol	resveratrol results in decreased expression of COL1A1 mRNA	22086758\|2539464
C059514	resveratrol	resveratrol inhibits the reaction [Carbon Tetrachloride affects the expression of COL1A1 mRNA]	23262250
C059514	resveratrol	"resveratrol inhibits the reaction [[cocoa butter co-treated with Cholesterol, Dietary co-treated with Cholates] results in increased expression of COL1A1 mRNA]"	25814186
C059514	resveratrol	resveratrol results in decreased expression of COL1A1 mRNA	19228061\|2326225
C059514	resveratrol	resveratrol inhibits the reaction [Dietary Fats results in increased expression of COL1A1 mRNA]	21852083
D015474	Isotretinoin	Isotretinoin results in decreased expression of COL1A1 mRNA	15972972
D015474	Isotretinoin	Isotretinoin results in decreased expression of COL1A1 protein	15972972
C042734	rifaximin	[NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of COL1A1 mRNA	22790967
C089032	rimonabant	rimonabant results in decreased expression of COL1A1 mRNA	21863215
C089730	rosiglitazone	rosiglitazone results in increased expression of COL1A1 mRNA	17148569
C089730	rosiglitazone	rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]	19147827
C089730	rosiglitazone	rosiglitazone results in decreased expression of COL1A1 mRNA	11916924\|1202120
C089730	rosiglitazone	rosiglitazone inhibits the reaction [AGT protein results in increased expression of COL1A1 mRNA]	18278065
C089730	rosiglitazone	rosiglitazone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	15980055
C089730	rosiglitazone	rosiglitazone results in increased expression of COL1A1 mRNA	19397913\|2117241
C089730	rosiglitazone	rosiglitazone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	19147827
C041376	rosmarinic acid	rosmarinic acid results in decreased expression of COL1A1 mRNA	27235791
C041376	rosmarinic acid	rosmarinic acid inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	28789951
C041376	rosmarinic acid	rosmarinic acid results in decreased expression of COL1A1 mRNA	28789951
C085746	rottlerin	rottlerin inhibits the reaction [[ABL1 protein results in increased phosphorylation of and results in decreased activity of PPARG protein] which results in increased expression of COL1A1 protein]	17030193
C085746	rottlerin	rottlerin inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17030193
C085746	rottlerin	rottlerin inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 protein]	17030193
D012504	Saralasin	Saralasin inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	20035857
C093642	SB 203580	SB 203580 inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]	18253093
C093642	SB 203580	SB 203580 results in decreased expression of COL1A1 mRNA	27235791
C093642	SB 203580	SB 203580 inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	12065697
C093642	SB 203580	SB 203580 inhibits the reaction [LEP protein results in increased expression of COL1A1 mRNA]	16996477
D012643	Selenium	[fulvic acid co-treated with Selenium deficiency] affects the metabolism of COL1A1 protein	8435081
C002979	selenomethylselenocysteine	selenomethylselenocysteine results in decreased expression of COL1A1 mRNA	18514395
C002979	selenomethylselenocysteine	selenomethylselenocysteine results in decreased expression of COL1A1 protein	18514395
D017632	Asbestos, Serpentine	"Asbestos, Serpentine results in increased expression of COL1A1 mRNA"	18039278
C016101	shikonin	shikonin results in decreased expression of COL1A1 mRNA	25591861
D000068677	Sildenafil Citrate	PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]]	25139994
D000068677	Sildenafil Citrate	Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]	25139994
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of COL1A1 mRNA	22300531
D012822	Silicon Dioxide	GREM1 protein inhibits the reaction [Silicon Dioxide results in increased expression of COL1A1 mRNA]	27428020
D012822	Silicon Dioxide	[IL1B protein affects the expression of COL1A1 mRNA] which affects the susceptibility to Silicon Dioxide	23640035
D012822	Silicon Dioxide	IL1B protein affects the reaction [Silicon Dioxide analog results in increased expression of COL1A1 mRNA]	25388157
D012822	Silicon Dioxide	IL1B protein affects the reaction [Silicon Dioxide results in increased expression of COL1A1 mRNA]	23640035
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of COL1A1 mRNA	25388157
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of COL1A1 mRNA	23640035\|2634525
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of COL1A1 mRNA	22431001
C440975	silybin	[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	16169303
D012838	Silymarin	Silymarin inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	24239723
D019821	Simvastatin	geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA]	16575855
D019821	Simvastatin	Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of COL1A1 mRNA]	16575855
D019821	Simvastatin	Simvastatin inhibits the reaction [CEBPZ binds to COL1A1 promoter]	16575855
D019821	Simvastatin	Simvastatin inhibits the reaction [SP1 binds to COL1A1 promoter]	16575855
D019821	Simvastatin	Simvastatin results in decreased expression of COL1A1 mRNA	16575855
D019821	Simvastatin	Simvastatin results in increased expression of COL1A1 mRNA	17252541
D019821	Simvastatin	Simvastatin results in increased expression of COL1A1 mRNA	10412775\|1497312
D020123	Sirolimus	Sirolimus results in decreased expression of COL1A1 mRNA	21865292
C439060	sirtinol	sirtinol results in decreased expression of COL1A1 protein	26251326
D012906	Smoke	Smoke results in increased expression of COL1A1 mRNA	21095227
C118258	SN50 peptide	SN50 peptide inhibits the reaction [Particulate Matter results in increased expression of COL1A1 mRNA]	12649123
C009277	sodium arsenate	sodium arsenate results in increased expression of COL1A1 mRNA	21795629
C017947	sodium arsenite	sodium arsenite results in increased expression of COL1A1 protein	23570992
C017947	sodium arsenite	sodium arsenite affects the methylation of COL1A1 gene	28589171
C017947	sodium arsenite	sodium arsenite results in decreased expression of COL1A1 mRNA	16507463
C017947	sodium arsenite	sodium arsenite results in decreased expression of COL1A1 protein	21925251
C017947	sodium arsenite	sodium arsenite results in decreased expression of COL1A1 mRNA	18812580
C017947	sodium arsenite	Quercetin analog inhibits the reaction [sodium arsenite results in increased expression of COL1A1 mRNA]	20371363
C017947	sodium arsenite	sodium arsenite results in increased expression of COL1A1 mRNA	20371363
C016104	sodium bichromate	sodium bichromate results in increased expression of COL1A1 mRNA	25993096
D012965	Sodium Chloride	Sodium Chloride results in increased expression of COL1A1 mRNA	23634900
D012982	Sodium, Dietary	"carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA]"	11682445
D012982	Sodium, Dietary	"[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA"	11682445
D012969	Sodium Fluoride	DKK1 protein inhibits the reaction [Sodium Fluoride results in increased expression of COL1A1 mRNA]	24300170
D012969	Sodium Fluoride	Sodium Fluoride results in decreased expression of COL1A1 mRNA	21093551
D012969	Sodium Fluoride	Sodium Fluoride results in increased expression of COL1A1 mRNA	24300170
D018038	Sodium Selenite	[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of COL1A1 mRNA	23274088
D018038	Sodium Selenite	Sodium Selenite results in decreased expression of COL1A1 mRNA	23274088
C471405	sorafenib	sorafenib inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	21360571
C471405	sorafenib	sorafenib results in decreased expression of COL1A1 mRNA	24321339
C517409	stattic	stattic inhibits the reaction [IL6 protein results in increased expression of COL1A1 mRNA]	25740948
C517409	stattic	stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA]	25740948
D013311	Streptozocin	Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]	28700904
D013311	Streptozocin	Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]	28700904
D013311	Streptozocin	Streptozocin results in increased expression of COL1A1 mRNA	28700904
D010042	Ouabain	MIR29B1 mRNA inhibits the reaction [Ouabain results in increased expression of COL1A1 mRNA]	26702050
D010042	Ouabain	Ouabain results in increased expression of COL1A1 mRNA	26702050
D012460	Sulfasalazine	Sulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	15633128
C473478	sunitinib	sunitinib results in decreased expression of COL1A1 mRNA	27235791
C473478	sunitinib	Carnitine inhibits the reaction [sunitinib results in increased expression of COL1A1 mRNA]	26581635
C473478	sunitinib	sunitinib results in decreased expression of COL1A1 mRNA	24321339
C473478	sunitinib	sunitinib results in increased expression of COL1A1 mRNA	26581635
D014284	Triiodothyronine	Triiodothyronine promotes the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	18031379
D014284	Triiodothyronine	Triiodothyronine results in increased expression of COL1A1 mRNA	18031379
D013605	T-2 Toxin	T-2 Toxin results in decreased expression of COL1A1 mRNA	22800716
D013629	Tamoxifen	Tamoxifen affects the expression of COL1A1 mRNA	17555576
C047246	temozolomide	COL1A1 mRNA affects the susceptibility to temozolomide	16365179
C012568	terbufos	terbufos results in increased methylation of COL1A1 promoter	22847954
D013739	Testosterone	Testosterone results in decreased expression of COL1A1 mRNA	22138414
D013739	Testosterone	Testosterone results in increased expression of COL1A1 mRNA	19693291
D013739	Testosterone	Testosterone results in increased expression of COL1A1 mRNA	15917159
C004648	testosterone enanthate	testosterone enanthate affects the expression of COL1A1 mRNA	17440010
C010792	testosterone undecanoate	[testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of COL1A1 mRNA	19074003
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of COL1A1 mRNA	22574217
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of COL1A1 mRNA	20106945
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of COL1A1 mRNA	20067830
D013749	Tetrachlorodibenzodioxin	NFE2L2 gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of COL1A1 mRNA]	21846477
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of COL1A1 mRNA	20702594\|2157046
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL1A1 mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA]	18670907
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27693115
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of COL1A1 mRNA	15034205\|1532836
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of COL1A1 mRNA	20959002
D013755	Tetradecanoylphorbol Acetate	[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL1A1 mRNA	25613284
C017953	tetramethylpyrazine	NFE2L2 protein promotes the reaction [tetramethylpyrazine results in decreased expression of COL1A1 mRNA]	27477297
C017953	tetramethylpyrazine	NFE2L2 protein promotes the reaction [tetramethylpyrazine results in decreased expression of COL1A1 protein]	27477297
C017953	tetramethylpyrazine	tetramethylpyrazine results in decreased expression of COL1A1 mRNA	27477297
C017953	tetramethylpyrazine	tetramethylpyrazine results in decreased expression of COL1A1 protein	27477297
C017953	tetramethylpyrazine	NFE2L2 affects the reaction [tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]]	27837167
C017953	tetramethylpyrazine	NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]]	27477297
C017953	tetramethylpyrazine	NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]]	27477297
C017953	tetramethylpyrazine	tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]	27477297
C017953	tetramethylpyrazine	tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]	27477297
C017953	tetramethylpyrazine	tetramethylpyrazine inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	27837167
C017953	tetramethylpyrazine	tetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of COL1A1 mRNA]	23022513
C019107	tetramethylthiourea	"tetramethylthiourea inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]"	11306436
C009438	tetrandrine	tetrandrine results in decreased expression of COL1A1 mRNA	27235791
D013792	Thalidomide	Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	26221080
D013792	Thalidomide	Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 protein]	26221080
D013806	Theophylline	Theophylline inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	16430859
D013806	Theophylline	Theophylline promotes the reaction [Dexamethasone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	16430859
D013853	Thioacetamide	Thioacetamide results in increased expression of COL1A1 mRNA	17997003
D013853	Thioacetamide	CNR1 gene mutant form inhibits the reaction [[Ethanol co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA]	21863215
D013853	Thioacetamide	"Drugs, Chinese Herbal inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]"	18606216
D013853	Thioacetamide	[Ethanol co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA	21863215
D013853	Thioacetamide	Grape Seed Proanthocyanidins inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	22863721
D013853	Thioacetamide	Grape Seed Proanthocyanidins inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]	22863721
D013853	Thioacetamide	IL10 protein inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	16126171
D013853	Thioacetamide	LEP protein affects the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	12085344
D013853	Thioacetamide	LEP protein promotes the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	11481614
D013853	Thioacetamide	MGAT5 protein affects the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	23798564
D013853	Thioacetamide	POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	16511523
D013853	Thioacetamide	[Thioacetamide co-treated with Ethanol] results in increased expression of COL1A1 protein	16780996
D013853	Thioacetamide	[Thioacetamide co-treated with LEP protein] results in increased expression of COL1A1 mRNA	16097051
D013853	Thioacetamide	Thioacetamide results in increased expression of COL1A1 mRNA	11481614\|1208534
D013853	Thioacetamide	Thioacetamide results in increased expression of COL1A1 protein	22863721
D013853	Thioacetamide	"1,3-dimethylthiourea inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]"	11682029
D013853	Thioacetamide	Curcumin inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	17355460
D013853	Thioacetamide	Cysteine inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15158331
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] affects the expression of COL1A1 mRNA	23830814
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of COL1A1 mRNA	28943392
D013853	Thioacetamide	Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]	11682029
D013853	Thioacetamide	"Drugs, Chinese Herbal inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]"	17629604
D013853	Thioacetamide	halofuginone inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	11172339\|1217562
D013853	Thioacetamide	halofuginone inhibits the reaction [Thioacetamide results in increased expression of COL1A1 protein]	12175628\|1473909
D013853	Thioacetamide	Methionine inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15158331
D013853	Thioacetamide	pirinixic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15474484
D013853	Thioacetamide	pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	15078482
D013853	Thioacetamide	Thioacetamide results in increased expression of COL1A1 mRNA	11172339\|1217562
D013853	Thioacetamide	Thioacetamide results in increased expression of COL1A1 protein	11682029\|1217562
D013853	Thioacetamide	Thioctic Acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	21251946
D008063	Thioctic Acid	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] affects the expression of COL1A1 mRNA	23830814
D008063	Thioctic Acid	Thioctic Acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]	21251946
C003466	thymoquinone	thymoquinone inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27688165
C003466	thymoquinone	thymoquinone inhibits the reaction [Ethanol results in increased expression of COL1A1 protein]	27688165
C003466	thymoquinone	thymoquinone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]	27375216
C032628	tin protoporphyrin IX	tin protoporphyrin IX inhibits the reaction [Quercetin inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]	21216973
D014025	Titanium	Titanium results in decreased expression of COL1A1 mRNA	11216681
D014025	Titanium	Titanium results in increased expression of COL1A1 mRNA	15914587
C009495	titanium dioxide	titanium dioxide results in decreased expression of COL1A1 mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased expression of COL1A1 protein	27189315
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of and results in increased secretion of COL1A1 protein	22761892
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of COL1A1 mRNA	22761892
D014050	Toluene	Toluene results in increased expression of COL1A1 mRNA	22967744
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of COL1A1 mRNA	25729387
D014108	Tosylphenylalanyl Chloromethyl Ketone	Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Acetaldehyde results in increased expression of COL1A1 mRNA]	17952619
D014118	Toxins, Biological	"Toxins, Biological affects the expression of COL1A1 mRNA"	19682533
D014148	Tranexamic Acid	Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA]	24633426
D014212	Tretinoin	Tretinoin results in decreased expression of COL1A1 mRNA	20530235
D014212	Tretinoin	Tretinoin inhibits the reaction [TGFB1 results in increased expression of COL1A1 mRNA]	21274875
D014212	Tretinoin	Tretinoin inhibits the reaction [TGFB1 results in increased expression of COL1A1 protein]	21274875
D014212	Tretinoin	Tretinoin results in decreased expression of COL1A1 mRNA	23724009
D014212	Tretinoin	Tretinoin results in increased expression of COL1A1 mRNA	17034753\|2193413
D014212	Tretinoin	Tretinoin results in decreased expression of COL1A1 mRNA	12969142\|2127487
C011559	tributyltin	tributyltin results in increased expression of COL1A1 mRNA	21683754
C447082	tricarbonyldichlororuthenium (II) dimer	tricarbonyldichlororuthenium (II) dimer inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	21216973
C447082	tricarbonyldichlororuthenium (II) dimer	tricarbonyldichlororuthenium (II) dimer inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]	21216973
D014241	Trichloroethylene	Trichloroethylene results in increased expression of COL1A1 mRNA	25055964
D014241	Trichloroethylene	[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of COL1A1 mRNA	17905399
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
C012589	trichostatin A	trichostatin A affects the expression of COL1A1 mRNA	28542535
C012589	trichostatin A	trichostatin A results in increased expression of COL1A1 mRNA	24935251\|2627250
C012589	trichostatin A	trichostatin A inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 protein]	27396813
C012589	trichostatin A	trichostatin A results in decreased expression of COL1A1 mRNA	15901671
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of COL1A1 mRNA	19042947
D014302	Trinitrobenzenesulfonic Acid	stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA]	25740948
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA	17982090\|2574094
C057693	troglitazone	troglitazone inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]	18253093
C057693	troglitazone	troglitazone results in decreased expression of COL1A1 mRNA	16813520
C057693	troglitazone	troglitazone results in increased expression of COL1A1 mRNA	28973697
C057693	troglitazone	troglitazone affects the expression of COL1A1 mRNA	15211114
D017973	Tungsten Compounds	Tungsten Compounds results in decreased expression of COL1A1 mRNA	28666766
C113580	U 0126	"U 0126 inhibits the reaction [1,25-dihydroxyvitamin D results in increased expression of COL1A1 mRNA]"	15331595
C113580	U 0126	U 0126 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]	28987794
C113580	U 0126	"U 0126 promotes the reaction [1,25-dihydroxyvitamin D results in increased expression of COL1A1 mRNA]"	15331595
D014635	Valproic Acid	[Hydralazine co-treated with Valproic Acid] results in increased expression of COL1A1 mRNA	17183730
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL1A1 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of COL1A1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased expression of COL1A1 mRNA	27235791\|2915479
D014635	Valproic Acid	Valproic Acid results in increased expression of COL1A1 mRNA	23179753\|2627250
D014635	Valproic Acid	Valproic Acid results in decreased expression of COL1A1 protein	26251326
D014635	Valproic Acid	Valproic Acid results in increased expression of COL1A1 mRNA	24896083
D014635	Valproic Acid	Valproic Acid results in decreased expression of COL1A1 mRNA	15901671
D014638	Vanadates	Vanadates results in decreased expression of COL1A1 mRNA	22714537
D014639	Vanadium	Vanadium results in decreased expression of COL1A1 mRNA	19000753
C066075	vanadium pentoxide	vanadium pentoxide results in decreased expression of COL1A1 mRNA	17459161
D001335	Vehicle Emissions	Vehicle Emissions results in decreased expression of COL1A1 mRNA	19165385
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of COL1A1 mRNA	12649123
D014700	Verapamil	Verapamil inhibits the reaction [Iron-Dextran Complex results in increased expression of COL1A1 protein]	27095094
D014801	Vitamin A	Vitamin A results in increased expression of COL1A1 mRNA	17034753
D014801	Vitamin A	[Cryptoxanthins co-treated with Vitamin A] results in increased expression of COL1A1 mRNA	15962303
D014801	Vitamin A	Vitamin A results in increased expression of COL1A1 mRNA	15962303
D009536	Niacinamide	Niacinamide inhibits the reaction [resveratrol inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]]	25707573
D009536	Niacinamide	Niacinamide results in decreased expression of COL1A1 mRNA	16813520
D009536	Niacinamide	Niacinamide results in decreased expression of COL1A1 mRNA	16813520
D014810	Vitamin E	[silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]	16169303
D014812	Vitamin K	Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA]	23117658
D014812	Vitamin K	[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA	23117658
D024482	Vitamin K 2	Vitamin K 2 results in decreased expression of COL1A1 mRNA	19675304
D024483	Vitamin K 3	Vitamin K 3 results in decreased expression of COL1A1 mRNA	19675304
D014859	Warfarin	Warfarin inhibits the reaction [BMP2 protein results in increased expression of COL1A1 mRNA]	21910061
D014859	Warfarin	Quercetin inhibits the reaction [[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA]	23117658
D014859	Warfarin	Quercetin inhibits the reaction [Warfarin results in increased expression of COL1A1 mRNA]	23223575
D014859	Warfarin	[Warfarin co-treated with Vitamin K] results in increased expression of COL1A1 mRNA	23117658
D014859	Warfarin	Warfarin results in increased expression of COL1A1 mRNA	23223575
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical affects the expression of COL1A1 mRNA"	25208076
C108830	Y 27632	Y 27632 inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]	21439370\|2351778
C108830	Y 27632	Y 27632 inhibits the reaction [Oxygen results in increased expression of COL1A1 mRNA]	21439370
D015032	Zinc	Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA]	17203194
D015032	Zinc	[Genistein co-treated with Zinc] results in increased expression of COL1A1 mRNA	17203194
D015032	Zinc	[Zinc binds to calcium silicate] which results in increased expression of COL1A1 mRNA	23483914
D015032	Zinc	Zinc deficiency results in decreased expression of COL1A1 mRNA	16140947\|2189322
D015032	Zinc	Zinc inhibits the reaction [Zinc deficiency results in decreased expression of COL1A1 mRNA]	16140947
C016837	zinc chloride	"[zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA"	19913120
C016837	zinc chloride	zinc chloride inhibits the reaction [Cadmium Chloride results in increased expression of COL1A1 mRNA]	15499971
D019287	Zinc Sulfate	Cycloheximide inhibits the reaction [[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA]	17203194
D019287	Zinc Sulfate	[Genistein co-treated with Zinc Sulfate] results in increased expression of COL1A1 mRNA	17203194
C088658	zoledronic acid	zoledronic acid results in decreased expression of COL1A1 mRNA	19597852
C088658	zoledronic acid	zoledronic acid results in decreased expression of COL1A1 protein	19597852
C088658	zoledronic acid	zoledronic acid results in increased expression of COL1A1 mRNA	28871336
C088658	zoledronic acid	Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]	28871336
C088658	zoledronic acid	SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]	28871336
C088658	zoledronic acid	zoledronic acid results in increased expression of COL1A1 mRNA	28871336

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0002020	protease binding	-	IPI	19932771
GO:0005201	extracellular matrix structural constituent	-	IBA	21873635
GO:0005515	protein binding	-	IPI	14749390 18375391 20015075 20541508 25290767
GO:0030020	extracellular matrix structural constituent conferring tensile strength	-	HDA	20551380 27559042
GO:0030020	extracellular matrix structural constituent conferring tensile strength	-	ISS	-
GO:0042802	identical protein binding	-	IDA	17211858
GO:0046872	metal ion binding	-	IEA	-
GO:0048407	platelet-derived growth factor binding	-	IDA	8900172

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001501	skeletal system development	-	IBA	21873635
GO:0001501	skeletal system development	-	IMP	1874719 8097422 14976317
GO:0001503	ossification	-	IBA	21873635
GO:0001568	blood vessel development	-	IBA	21873635
GO:0001568	blood vessel development	-	IMP	17211858
GO:0001649	osteoblast differentiation	-	IEA	-
GO:0001957	intramembranous ossification	-	IEA	-
GO:0001958	endochondral ossification	-	IEA	-
GO:0007596	blood coagulation	-	TAS	-
GO:0007601	visual perception	-	IMP	17557158
GO:0007605	sensory perception of sound	-	IMP	17489845
GO:0009612	response to mechanical stimulus	-	IBA	21873635
GO:0010718	positive regulation of epithelial to mesenchymal transition	-	IDA	20018240
GO:0010812	negative regulation of cell-substrate adhesion	-	IEA	-
GO:0015031	protein transport	-	IEA	-
GO:0030168	platelet activation	-	TAS	-
GO:0030198	extracellular matrix organization	-	IBA	21873635
GO:0030198	extracellular matrix organization	-	TAS	-
GO:0030199	collagen fibril organization	-	IMP	14976317 15095409 17211858 18375391
GO:0030335	positive regulation of cell migration	-	IDA	20018240
GO:0031960	response to corticosteroid	-	IEA	-
GO:0032355	response to estradiol	-	IEA	-
GO:0032964	collagen biosynthetic process	-	IMP	15095409
GO:0034504	protein localization to nucleus	-	IDA	20018240
GO:0034505	tooth mineralization	-	IMP	17118335
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	-	IBA	21873635
GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	-	IEA	-
GO:0042542	response to hydrogen peroxide	-	IEA	-
GO:0043434	response to peptide hormone	-	IEA	-
GO:0043588	skin development	-	IBA	21873635
GO:0043589	skin morphogenesis	-	IMP	17211858
GO:0044344	cellular response to fibroblast growth factor stimulus	-	IEA	-
GO:0044691	tooth eruption	-	IEA	-
GO:0045893	positive regulation of transcription, DNA-templated	-	IDA	20018240
GO:0048706	embryonic skeletal system development	-	IMP	18553566
GO:0050776	regulation of immune response	-	TAS	-
GO:0050900	leukocyte migration	-	TAS	-
GO:0051591	response to cAMP	-	IEA	-
GO:0055093	response to hyperoxia	-	IEA	-
GO:0060325	face morphogenesis	-	IEA	-
GO:0060346	bone trabecula formation	-	IEA	-
GO:0060351	cartilage development involved in endochondral bone morphogenesis	-	IEA	-
GO:0070208	protein heterotrimerization	-	IEA	-
GO:0071230	cellular response to amino acid stimulus	-	IEA	-
GO:0071260	cellular response to mechanical stimulus	-	IEA	-
GO:0071300	cellular response to retinoic acid	-	IEA	-
GO:0071306	cellular response to vitamin E	-	IEA	-
GO:0071356	cellular response to tumor necrosis factor	-	IEA	-
GO:0071364	cellular response to epidermal growth factor stimulus	-	IEA	-
GO:0071560	cellular response to transforming growth factor beta stimulus	-	IEA	-
GO:0090263	positive regulation of canonical Wnt signaling pathway	-	IDA	20018240
GO:1902618	cellular response to fluoride	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005576	extracellular region	-	HDA	27068509
GO:0005576	extracellular region	-	TAS	-
GO:0005584	collagen type I trimer	-	IBA	21873635
GO:0005584	collagen type I trimer	-	IDA	19932771
GO:0005584	collagen type I trimer	-	IMP	14976317 17576241
GO:0005615	extracellular space	-	HDA	20551380
GO:0005615	extracellular space	-	IBA	21873635
GO:0005615	extracellular space	-	IMP	20603131
GO:0005737	cytoplasm	-	IBA	21873635
GO:0005788	endoplasmic reticulum lumen	-	TAS	-
GO:0005794	Golgi apparatus	-	IEA	-
GO:0030141	secretory granule	-	IEA	-
GO:0031012	extracellular matrix	-	HDA	23658023
GO:0062023	collagen-containing extracellular matrix	-	HDA	27559042
GO:0062023	collagen-containing extracellular matrix	colocalizes_with	HDA	20551380
GO:0062023	collagen-containing extracellular matrix	colocalizes_with	ISS	22261194

KEGG ID	KEGG Term
hsa04510	Focal adhesion
hsa04512	ECM-receptor interaction
hsa04974	Protein digestion and absorption
hsa05146	Amoebiasis

Reactome ID	Reactome Term	Evidence
R-HSA-109582	Hemostasis	IEA
R-HSA-109582	Hemostasis	TAS
R-HSA-114604	GPVI-mediated activation cascade	TAS
R-HSA-1280218	Adaptive Immune System	TAS
R-HSA-1442490	Collagen degradation	TAS
R-HSA-1442490	Collagen degradation	IEA
R-HSA-1474228	Degradation of the extracellular matrix	TAS
R-HSA-1474228	Degradation of the extracellular matrix	IEA
R-HSA-1474244	Extracellular matrix organization	TAS
R-HSA-1474244	Extracellular matrix organization	IEA
R-HSA-1474290	Collagen formation	TAS
R-HSA-162582	Signal Transduction	TAS
R-HSA-1650814	Collagen biosynthesis and modifying enzymes	TAS
R-HSA-168256	Immune System	TAS
R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	TAS
R-HSA-2022090	Assembly of collagen fibrils and other multimeric structures	TAS
R-HSA-202733	Cell surface interactions at the vascular wall	TAS
R-HSA-212436	Generic Transcription Pathway	IEA
R-HSA-216083	Integrin cell surface interactions	TAS
R-HSA-216083	Integrin cell surface interactions	IEA
R-HSA-2173782	Binding and Uptake of Ligands by Scavenger Receptors	IEA
R-HSA-2214320	Anchoring fibril formation	TAS
R-HSA-2243919	Crosslinking of collagen fibrils	TAS
R-HSA-3000170	Syndecan interactions	IEA
R-HSA-3000171	Non-integrin membrane-ECM interactions	TAS
R-HSA-3000171	Non-integrin membrane-ECM interactions	IEA
R-HSA-3000178	ECM proteoglycans	TAS
R-HSA-3000178	ECM proteoglycans	IEA
R-HSA-3000480	Scavenging by Class A Receptors	IEA
R-HSA-430116	GP1b-IX-V activation signalling	TAS
R-HSA-5653656	Vesicle-mediated transport	IEA
R-HSA-6806834	Signaling by MET	TAS
R-HSA-73857	RNA Polymerase II Transcription	IEA
R-HSA-74160	Gene expression (Transcription)	IEA
R-HSA-75892	Platelet Adhesion to exposed collagen	IEA
R-HSA-75892	Platelet Adhesion to exposed collagen	TAS
R-HSA-76002	Platelet activation, signaling and aggregation	TAS
R-HSA-76009	Platelet Aggregation (Plug Formation)	TAS
R-HSA-8874081	MET activates PTK2 signaling	TAS
R-HSA-8875878	MET promotes cell motility	TAS
R-HSA-8878166	Transcriptional regulation by RUNX2	IEA
R-HSA-8940973	RUNX2 regulates osteoblast differentiation	IEA
R-HSA-8941326	RUNX2 regulates bone development	IEA
R-HSA-8948216	Collagen chain trimerization	TAS
R-HSA-9006934	Signaling by Receptor Tyrosine Kinases	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
16009674	Influence of IL-6, COL1A1, and VDR gene polymorphisms on bone mineral density in Crohn's disease. (2005 Nov)	Todhunter CE	Gut
24566004	Combined effects of collagen type I alpha1 (COL1A1) Sp1 polymorphism and osteoporosis risk factors on bone mineral density in Turkish postmenopausal women. (2014 May 1)	Kurt-Sirin O	Gene
11566920	Effect of a COL1A1 Sp1 binding site polymorphism on arterial pulse wave velocity: an index of compliance. (2001 Sep)	Brull DJ	Hypertension
15530908	Total homocysteine is not a determinant of arterial pulse wave velocity in young healthy adults. (2004 Dec)	Woodside JV	Atherosclerosis
22708121	Juglans mandshurica leaf extract protects skin fibroblasts from damage by regulating the oxidative defense system. (2012 May 4)	Park G	Biochem Biophys Res Commun
29568927	miR-185 and miR-29a are similarly expressed in the bronchoalveolar lavage cells in IPF and lung cancer but common targets DNMT1 and COL1A1 show disease specific patterns. (2018 May)	Bibaki E	Mol Med Rep
29614203	Changes in the expression of matrix extracellular genes and TGFB family members in rotator cuff tears. (2018 Apr 3)	Belangero PS	J Orthop Res
18226133	Effects of hormone replacement therapy on bone mineral density in Turkish patients with or without COL1A1 Sp1 binding site polymorphism. (2008 Feb)	Simsek M	J Obstet Gynaecol Res
25514196	Comprehensive analysis of genes, pathways, and TFs in nonsmoking Taiwan females with lung cancer. (2015 Mar)	Lv M	Exp Lung Res
20818932	Prevention of liver fibrosis by triple helix-forming oligodeoxyribonucleotides targeted to the promoter region of type I collagen gene. (2010 Oct)	Koilan S	Oligonucleotides
21791674	Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium. (2011 Aug 17)	Campa D	J Natl Cancer Inst
21396799	Genetic polymorphisms and other risk factors associated with bisphosphonate induced osteonecrosis of the jaw. (2011 Jun)	Katz J	Int J Oral Maxillofac Surg
23030247	Nicotine alters MicroRNA expression and hinders human adult stem cell regenerative potential. (2013 Mar 1)	Ng TK	Stem Cells Dev