Gene: COL3A1

1281
EDS4A|EDSVASC
collagen type III alpha 1 chain
protein-coding
2q32.2
Ensembl:ENSG00000168542 MIM:120180 Vega:OTTHUMG00000132648 UniprotKB:P02461
NG_007404.1
PubMed
ND
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.984e-1 (AD)  2.016e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
COL14A10.87
COL8A10.864
COL6A30.857
MGP0.851
GPX80.833
COL1A20.823
GJA50.813
LUM0.81
TBX180.804
COL1A10.796

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ASPDH-0.407
DBP-0.384
TMEM53-0.375
HAGHL-0.374
MYH7B-0.37
CCDC24-0.366
FAM43B-0.365
ABCB9-0.364
HAS1-0.363
MYADML2-0.362

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00048Collagenase clostridium histolyticumBiotechDrug9001-12-1Approved|InvestigationalTarget
ID Drug Name Action PubMed
C5495001-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased expression of COL3A1 mRNA]27678262
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of COL3A1 mRNA"19162173
C5815721-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]25827057
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of COL3A1 mRNA]27025157
C0612822-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein27595240
C0612822-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosineCTNNB1 protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein]27595240
C5029712-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL3A1 mRNA]15723089
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl affects the expression of COL3A1 mRNA"20638727
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of COL3A1 mRNA"23196670
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of COL3A1 mRNA"20959002
C5201644-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid[4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid co-treated with Carbon Tetrachloride] results in increased expression of COL3A1 protein12512042
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of COL3A1 mRNA"25380136
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL3A1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL3A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL3A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL3A1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of COL3A1 mRNA21420995
D000082AcetaminophenAcetaminophen results in increased expression of COL3A1 mRNA28286204
D000082AcetaminophenEGR1 protein affects the reaction [Acetaminophen results in increased expression of COL3A1 mRNA]28286204
D000082AcetaminophenMAP3K5 protein affects the reaction [Acetaminophen results in increased expression of COL3A1 mRNA]18700144
C056165acetovanilloneacetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]16531806
C056165acetovanilloneacetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]16531806
D020106AcrylamideAcrylamide results in decreased expression of COL3A1 mRNA28959563
C526957alisol B 23-acetatealisol B 23-acetate inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]28578904
D000643Ammonium ChlorideAmmonium Chloride affects the expression of COL3A1 mRNA16483693
C053506ammonium perchlorateammonium perchlorate results in increased expression of COL3A1 mRNA17456394
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of COL3A1 mRNA"22863853
D000806Angiotensin-Converting Enzyme InhibitorsAngiotensin-Converting Enzyme Inhibitors results in decreased expression of COL3A1 mRNA15667801
C025657arsenic acidarsenic acid results in increased expression of COL3A1 mRNA18296743
C025657arsenic acidDietary Fats promotes the reaction [arsenic acid results in increased expression of COL3A1 mRNA]18296743
C015001arsenitearsenite results in increased expression of COL3A1 mRNA18296743
C015001arseniteDietary Fats promotes the reaction [arsenite results in increased expression of COL3A1 mRNA]18296743
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased expression of COL3A1 mRNA"19219932
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased expression of COL3A1 mRNA"22251266
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of COL3A1 mRNA"11250057
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of COL3A1 mRNA"18192500
D017638Asbestos, Crocidolite"MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of COL3A1 mRNA]"18192500
C011669ascorbate-2-phosphateascorbate-2-phosphate results in decreased expression of COL3A1 mRNA17306970
C011669ascorbate-2-phosphateascorbate-2-phosphate results in increased expression of COL3A1 mRNA17306970
D001241AspirinAspirin results in decreased expression of COL3A1 mRNA15456535
C020976azelastineazelastine results in decreased expression of COL3A1 mRNA8919039
C547126AZM551248AZM551248 results in increased expression of COL3A1 mRNA22323515
C030935benz(a)anthracene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL3A1 mRNA27858113
D001554Benzene[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of COL3A1 mRNA17905399
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL3A1 mRNA27858113
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of COL3A1 mRNA26377693
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of COL3A1 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of COL3A1 mRNA22342234
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL3A1 mRNA27858113
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of COL3A1 mRNA20713471|2156981
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of COL3A1 mRNA21839799
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of COL3A1 mRNA"20382639
D004958EstradiolEstradiol results in increased expression of COL3A1 mRNA15902152
D004958EstradiolEstradiol affects the expression of COL3A1 protein20864640
D004958EstradiolEstradiol results in increased expression of COL3A1 mRNA19484750
D001663BilirubinBilirubin results in decreased expression of COL3A1 mRNA20196124
C006780bisphenol Abisphenol A results in decreased expression of COL3A1 mRNA27809950
C006780bisphenol A2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of COL3A1 mRNA]27025157
C006780bisphenol Abisphenol A affects the expression of COL3A1 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of COL3A1 mRNA27025157
C006780bisphenol Afulvestrant inhibits the reaction [bisphenol A results in increased expression of COL3A1 mRNA]27025157
D001761BleomycinMIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]28726637
D001761BleomycinBleomycin results in increased expression of COL3A1 mRNA26817844|2872663
D001761BleomycinBleomycin results in decreased expression of COL3A1 protein25933445
D000551AmbroxolAmbroxol affects the reaction [Paraquat results in increased expression of COL3A1 mRNA]21921364
D002065BuspironeBuspirone results in decreased expression of COL3A1 mRNA24136188
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of COL3A1 mRNA15336504
D019256Cadmium ChlorideCadmium Chloride results in increased expression of COL3A1 mRNA12160620
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of COL3A1 mRNA24982889
C077793candesartan cilexetilcandesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of COL3A1 protein]27889505
D002211CapsaicinCapsaicin results in increased expression of COL3A1 mRNA20349343
D002244Carbon"[Carbon co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of COL3A1 mRNA"26880698
D002244CarbonCarbon results in increased expression of COL3A1 mRNA26880698
D002251Carbon Tetrachloride1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]25827057
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of COL3A1 mRNA17484886
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of COL3A1 mRNA15056808|1826369
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of COL3A1 protein27477297
D002251Carbon TetrachlorideNFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]]27477297
D002251Carbon Tetrachloridetetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]27477297
D002251Carbon Tetrachloride[4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid co-treated with Carbon Tetrachloride] results in increased expression of COL3A1 protein12512042
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of COL3A1 mRNA16239168
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of COL3A1 mRNA12632512|1715783
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of COL3A1 protein17157831|2350077
D002251Carbon TetrachlorideCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]22683883
D002251Carbon Tetrachloride"Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]"12632512
D002251Carbon TetrachloridePlant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]17157831
D002251Carbon TetrachloridePlant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]17157831
D002251Carbon TetrachloridePLAU protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]18481824
D002251Carbon Tetrachloridepuerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]23500774
C043211carvedilolcarvedilol inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA]10722803
C043211carvedilol"carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA]"11682445
C043211carvedilolcarvedilol results in decreased expression of COL3A1 protein11181017
D002737ChloropreneChloroprene results in decreased expression of COL3A1 mRNA23125180
D002793Cholic Acids[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D002793Cholic Acids[Cyclosporine co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D002793Cholic Acids[Ethinyl Estradiol co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D002793Cholic Acids[Methyltestosterone co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL3A1 mRNA20548288|2093899
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL3A1 mRNA22915297
D002794CholineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL3A1 mRNA]22915297
C031180chrysene[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of COL3A1 mRNA27858113
D002995Clofibric AcidClofibric Acid affects the expression of COL3A1 mRNA17602206
C018021cobaltous chloridecobaltous chloride results in decreased expression of COL3A1 mRNA21139344
D003042CocaineCocaine results in increased expression of COL3A1 mRNA9455993
D003300Copper[Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA24690739
D003300CopperCopper deficiency results in increased expression of COL3A1 mRNA17418555
D003474CurcuminCurcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]22683883
D016572Cyclosporine[Cyclosporine co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D003561CytarabineCytarabine results in decreased expression of COL3A1 mRNA21198554
D000069439DasatinibDasatinib results in increased expression of COL3A1 mRNA20579391
D003907DexamethasoneDexamethasone results in decreased expression of COL3A1 mRNA25047013
D003907DexamethasoneDexamethasone results in decreased expression of COL3A1 mRNA20032058
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of COL3A1 mRNA]20032058
D003994BucladesineBucladesine inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]11576339
D002945Cisplatin[Cisplatin co-treated with Paclitaxel] affects the expression of COL3A1 mRNA20705681
D002945CisplatinCOL3A1 mRNA results in decreased susceptibility to Cisplatin25199881
D004008DiclofenacDiclofenac results in decreased expression of COL3A1 mRNA26934552
D019259LamivudineLamivudine results in decreased expression of COL3A1 protein11738102
D004041Dietary FatsDietary Fats promotes the reaction [arsenic acid results in increased expression of COL3A1 mRNA]18296743
D004041Dietary FatsDietary Fats promotes the reaction [arsenite results in increased expression of COL3A1 mRNA]18296743
D004041Dietary FatsDietary Fats results in decreased expression of COL3A1 mRNA18042831
D004041Dietary FatsDietary Fats results in increased expression of COL3A1 mRNA18296743|2260994
D004041Dietary Fats"carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA]"11682445
D004041Dietary Fats[Ethanol co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA21051528
D004041Dietary Fats"[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA"11682445
D004041Dietary FatsDietary Fats results in increased expression of COL3A1 mRNA21852083
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats results in increased expression of COL3A1 mRNA]21852083
C058705diethyl malatediethyl malate affects the expression of COL3A1 mRNA24814887
C014476diethyl maleatediethyl maleate results in decreased expression of COL3A1 mRNA25270620
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of COL3A1 mRNA19638242
D002117CalcitriolCalcitriol results in decreased expression of COL3A1 mRNA26485663
D004128Dimethylnitrosamine2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL3A1 mRNA]15723089
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of COL3A1 mRNA15723089
D004164DiphosphonatesDiphosphonates results in decreased expression of COL3A1 mRNA19597852
D004176DipyridamoleDipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]11576339
D004176DipyridamoleN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]]11576339
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA24690739
D004237DiuronDiuron results in decreased expression of COL3A1 mRNA25152437
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL3A1 mRNA]28987794
D004317DoxorubicinCOL3A1 mRNA results in decreased susceptibility to Doxorubicin25199881
D004317DoxorubicinDoxorubicin results in decreased expression of COL3A1 mRNA16243910|1788872
D004317DoxorubicinDoxorubicin results in increased expression of COL3A1 mRNA15033991
D004317Doxorubicin[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of COL3A1 mRNA21040762
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]"12632512
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Thioacetamide results in increased expression of COL3A1 mRNA]"17629604
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of COL3A1 mRNA"12076858
D004642EmodinEmodin results in decreased expression of COL3A1 mRNA15288473
D004656EnalaprilEnalapril results in increased expression of COL3A1 mRNA25037058
D004656EnalaprilEnalapril results in decreased expression of COL3A1 mRNA17164399
C034959enterotoxin C, staphylococcal"enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]"26099602
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of COL3A1 protein]22101032
C015860ergosta-4,6,8(14),22-tetraen-3-one"ergosta-4,6,8(14),22-tetraen-3-one inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]"28578904
C074283estradiol 3-benzoateestradiol 3-benzoate results in decreased expression of COL3A1 mRNA14967907
D000431Ethanol[Ethanol co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA21051528
D000431EthanolEthanol results in increased expression of COL3A1 protein23274713
D000431EthanolGenistein inhibits the reaction [Ethanol results in increased expression of COL3A1 protein]23274713
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of COL3A1 mRNA17557909
C024565ethylene dichlorideethylene dichloride results in decreased expression of COL3A1 mRNA28189721
D018690Excitatory Amino Acid AgonistsDizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL3A1 mRNA]28987794
D018690Excitatory Amino Acid AgonistsExcitatory Amino Acid Agonists results in increased expression of COL3A1 mRNA28987794
D018690Excitatory Amino Acid AgonistsU 0126 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL3A1 mRNA]28987794
C049347fasudilfasudil results in decreased expression of COL3A1 mRNA22465603
D011345FenofibrateFenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]28871336
D000068876Fingolimod HydrochlorideFingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]24893116
D005472FluorouracilCOL3A1 protein affects the susceptibility to Fluorouracil16217747
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL3A1 mRNA20548288|2093899
C070081fulvestrantfulvestrant inhibits the reaction [bisphenol A results in increased expression of COL3A1 mRNA]27025157
C039281furanfuran results in increased expression of COL3A1 mRNA27387713
D005688GalactosamineGalactosamine results in increased expression of COL3A1 mRNA27876602
D005688GalactosamineGenistein inhibits the reaction [Galactosamine results in increased expression of COL3A1 mRNA]27876602
D019833GenisteinGenistein inhibits the reaction [Ethanol results in increased expression of COL3A1 protein]23274713
D019833GenisteinGenistein inhibits the reaction [Galactosamine results in increased expression of COL3A1 mRNA]27876602
D005938GlucocorticoidsGlucocorticoids results in decreased expression of COL3A1 mRNA16023836
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]17109745
D005947GlucoseGlucose deficiency affects the secretion of COL3A1 protein24802182
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of COL3A1 mRNA22634610
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of COL3A1 mRNA22634610
D006046Gold[Gold co-treated with Polyethylene Glycols] results in increased expression of COL3A1 mRNA19695318
D006118GriseofulvinGriseofulvin results in increased expression of COL3A1 mRNA12735108
D017313FenretinideFenretinide results in decreased expression of COL3A1 mRNA28973697
C492448ICG 001ICG 001 inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]28578904
C492448ICG 001Losartan promotes the reaction [ICG 001 inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]]28578904
C078038inchinko-toinchinko-to results in decreased expression of COL3A1 mRNA15288473
D007213IndomethacinIndomethacin results in increased expression of COL3A1 mRNA18299717
D007545IsoproterenolAGT inhibits the reaction [Isoproterenol results in increased expression of COL3A1 protein]20409916
D007545IsoproterenolIsoproterenol results in increased expression of COL3A1 mRNA9559417
D007545IsoproterenolIsoproterenol results in increased expression of COL3A1 protein20409916
D007545Isoproterenolmanidipine inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]9559417
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of COL3A1 mRNA26752646
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of COL3A1 mRNA26644586
C008281limonenelimonene results in increased expression of COL3A1 mRNA12815608
C482199lipopolysaccharide, E coli O55-B5"[Carbon co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of COL3A1 mRNA"26880698
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of COL3A1 mRNA"26880698
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of COL3A1 mRNA23585870|2733941
D008070LipopolysaccharidesLosartan inhibits the reaction [Lipopolysaccharides results in increased expression of COL3A1 mRNA]23585870
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [Thioacetamide results in increased expression of COL3A1 mRNA]17621560
D019808LosartanLosartan inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]28578904
D019808LosartanLosartan promotes the reaction [ICG 001 inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]]28578904
D019808LosartanLosartan inhibits the reaction [Lipopolysaccharides results in increased expression of COL3A1 mRNA]23585870
D019808LosartanLosartan inhibits the reaction [AGT protein results in increased secretion of COL3A1 protein]16539842
D019808LosartanLosartan inhibits the reaction [Paraquat results in increased expression of COL3A1 protein]25233898
D019808LosartanLosartan results in decreased expression of COL3A1 mRNA15100363
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of COL3A1 mRNA26378955
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of COL3A1 mRNA26378955
C054218manidipinemanidipine inhibits the reaction [Isoproterenol results in increased expression of COL3A1 mRNA]9559417
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL3A1 mRNA"27188386
D008694MethamphetamineMethamphetamine results in decreased expression of COL3A1 mRNA19564919
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of COL3A1 mRNA20548288|2093899
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL3A1 mRNA22915297
D008715MethionineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL3A1 mRNA]22915297
D008727MethotrexateCOL3A1 mRNA results in decreased susceptibility to Methotrexate25199881
D008727MethotrexateMethotrexate affects the expression of COL3A1 protein alternative form15787813
D008727MethotrexateMethotrexate results in increased expression of COL3A1 protein7577576|8667468
D008727MethotrexateMethotrexate results in increased expression of COL3A1 protein alternative form2297495|2566230
D008748MethylcholanthreneMethylcholanthrene results in decreased expression of COL3A1 mRNA20713471
C030957methylmercury II[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of COL3A1 mRNA17905399
D008777Methyltestosterone[Methyltestosterone co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D015735MifepristoneMifepristone results in decreased expression of COL3A1 mRNA25972201
C028577monobutyl phthalatemonobutyl phthalate affects the expression of COL3A1 mRNA19162170
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]]11576339
C028473N-acetyl-4-benzoquinoneimineN-acetyl-4-benzoquinoneimine results in increased expression of COL3A1 mRNA28286204
C003297nandrolone decanoatenandrolone decanoate results in increased expression of COL3A1 mRNA17906098
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of COL3A1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog affects the expression of COL3A1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of COL3A1 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of COL3A1 mRNA"25620056
D0150581-Naphthylisothiocyanate[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of COL3A1 mRNA27344345
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of COL3A1 mRNA25380136
C017096n-butoxyethanoln-butoxyethanol results in decreased expression of COL3A1 mRNA19812364
C051752nefazodonenefazodone results in decreased expression of COL3A1 mRNA24136188
C045863neo-gambogic acidneo-gambogic acid inhibits the reaction [[Silicon Dioxide results in increased expression of HMGB1 protein] which results in increased expression of COL3A1 protein]27616297
D009532NickelNickel results in increased expression of COL3A1 mRNA12540486
C022838nickel chloridenickel chloride affects the expression of COL3A1 mRNA22110744
C029938nickel sulfatenickel sulfate results in decreased expression of COL3A1 mRNA16166746
C012655nimesulidenimesulide results in decreased expression of COL3A1 mRNA24136188
D009638Norepinephrinecarvedilol inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA]10722803
D009638NorepinephrineNorepinephrine results in increased expression of COL3A1 mRNA10722803|1457759
D019787Linoleic AcidLinoleic Acid results in decreased expression of COL3A1 mRNA26240151
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of COL3A1 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of COL3A1 mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of COL3A1 mRNA24236059
D010100OxygenOxygen deficiency results in increased expression of COL3A1 mRNA24205000
D010126OzoneOzone results in increased expression of COL3A1 mRNA9820643
D010126OzoneOzone results in increased expression of COL3A1 mRNA16716893|8018336
C102487pachymic acidpachymic acid analog inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]28578904
D017239Paclitaxel[Cisplatin co-treated with Paclitaxel] affects the expression of COL3A1 mRNA20705681
D017239PaclitaxelCOL3A1 mRNA results in decreased susceptibility to Paclitaxel25199881
D000073878Palm OilPalm Oil results in decreased expression of COL3A1 mRNA18042831
D010269ParaquatADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]25945502
D010269ParaquatADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]25945502
D010269ParaquatParaquat results in increased expression of COL3A1 mRNA20035857|2594550
D010269ParaquatSaralasin inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]20035857
D010269Paraquat"enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]"26099602
D010269ParaquatFingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]24893116
D010269ParaquatParaquat results in increased expression of COL3A1 mRNA24893116|2530496
D010269Paraquat"plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]"26758514
D010269ParaquatAmbroxol affects the reaction [Paraquat results in increased expression of COL3A1 mRNA]21921364
D010269ParaquatLosartan inhibits the reaction [Paraquat results in increased expression of COL3A1 protein]25233898
D010269ParaquatParaquat results in increased expression of COL3A1 mRNA21921364|2587330
D010269ParaquatParaquat results in increased expression of COL3A1 protein25233898
C084656paricalcitolparicalcitol results in increased expression of COL3A1 mRNA25037058
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of COL3A1 mRNA26705709
D010431PentoxifyllinePentoxifylline results in decreased expression of COL3A1 protein11788567
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in decreased expression of COL3A1 mRNA22790973
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of COL3A1 mRNA19162173
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of COL3A1 mRNA19162173
D020913PerindoprilPerindopril results in decreased expression of COL3A1 mRNA12076858|1487103
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of COL3A1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of COL3A1 mRNA26272509
C006253pirinixic acidpirinixic acid results in decreased expression of COL3A1 mRNA17426115|1844570
C442842plant extract, Puerariae Radix"plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]"26758514
D010936Plant ExtractsPlant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 mRNA]17157831
D010936Plant ExtractsPlant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]17157831
D011092Polyethylene Glycols[Gold co-treated with Polyethylene Glycols] results in increased expression of COL3A1 mRNA19695318
D011192Potassium DichromatePotassium Dichromate results in increased expression of COL3A1 protein23718831
D011192Potassium DichromatePotassium Dichromate results in increased expression of COL3A1 mRNA23608068
D011374ProgesteroneProgesterone affects the expression of COL3A1 protein20864640
D011441PropylthiouracilPropylthiouracil affects the expression of COL3A1 mRNA24780913
C033607puerarinpuerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]23500774
D011692Puromycin AminonucleosidePuromycin Aminonucleoside results in increased expression of COL3A1 mRNA9527400
D011765Pyruvaldehydeepigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of COL3A1 protein]22101032
D011765PyruvaldehydePyruvaldehyde results in increased expression of COL3A1 protein22101032
D011794QuercetinQuercetin results in decreased expression of COL3A1 mRNA12653748|1708674
D011794QuercetinQuercetin results in decreased expression of COL3A1 protein12653748|1708674
D011794QuercetinQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL3A1 mRNA]22915297
C012526quercitrinquercitrin results in decreased expression of COL3A1 mRNA25193878
C052785rebamipiderebamipide results in increased expression of COL3A1 mRNA18299717
C059514resveratrolresveratrol affects the secretion of COL3A1 protein24802182
C059514resveratrolresveratrol results in decreased expression of COL3A1 mRNA24317052
C059514resveratrolresveratrol results in increased expression of COL3A1 protein22936809
C059514resveratrolresveratrol inhibits the reaction [DMD gene mutant form results in increased expression of COL3A1 mRNA]23297412
C059514resveratrolresveratrol results in decreased expression of COL3A1 mRNA25394648
C059514resveratrolresveratrol results in decreased expression of COL3A1 mRNA19228061
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats results in increased expression of COL3A1 mRNA]21852083
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in decreased expression of COL3A1 protein]22936809
D015474IsotretinoinIsotretinoin results in decreased expression of COL3A1 mRNA15972972
D015474IsotretinoinIsotretinoin results in decreased expression of COL3A1 protein15972972
C089730rosiglitazonerosiglitazone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]18278065
C089730rosiglitazonerosiglitazone results in increased expression of COL3A1 mRNA19397913
C041376rosmarinic acidrosmarinic acid inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 mRNA]28789951
C041376rosmarinic acidrosmarinic acid results in decreased expression of COL3A1 mRNA28789951
D012504SaralasinSaralasin inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]20035857
D012524SarinSarin results in decreased expression of COL3A1 mRNA19522546
C534628SCH 23390SCH 23390 results in decreased expression of COL3A1 mRNA19564919
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of COL3A1 mRNA"21514415
D017632Asbestos, Serpentine"SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of COL3A1 mRNA]"21514415
C016101shikoninshikonin results in decreased expression of COL3A1 mRNA25591861
D012822Silicon DioxideHMGB1 protein promotes the reaction [[Silicon Dioxide results in increased secretion of HMGB1 protein] which results in increased expression of COL3A1 protein]27616297
D012822Silicon DioxideIL1B protein affects the reaction [Silicon Dioxide analog results in increased expression of COL3A1 mRNA]25388157
D012822Silicon Dioxideneo-gambogic acid inhibits the reaction [[Silicon Dioxide results in increased expression of HMGB1 protein] which results in increased expression of COL3A1 protein]27616297
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of COL3A1 mRNA25388157
D012822Silicon Dioxide[Silicon Dioxide results in increased secretion of HMGB1 protein] which results in increased expression of COL3A1 protein27616297
D012822Silicon DioxideSilicon Dioxide results in decreased expression of COL3A1 mRNA22431001
D019821SimvastatinSimvastatin results in increased expression of COL3A1 mRNA17183729
D019821SimvastatinSimvastatin results in increased expression of COL3A1 mRNA10412775|1627430
D019821SimvastatinSimvastatin results in decreased expression of COL3A1 mRNA16414398
C017947sodium arsenitesodium arsenite results in decreased expression of COL3A1 mRNA18812580
C017947sodium arsenitesodium arsenite results in decreased expression of COL3A1 protein19095001
C017947sodium arsenitesodium arsenite results in increased expression of COL3A1 mRNA19095001
C017947sodium arsenitecandesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of COL3A1 protein]27889505
C017947sodium arsenitesodium arsenite results in decreased expression of COL3A1 mRNA19072884
C017947sodium arsenitesodium arsenite results in increased expression of COL3A1 protein27889505
D012982Sodium, Dietary"carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA]"11682445
D012982Sodium, Dietary"[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA"11682445
D018038Sodium SeleniteSodium Selenite results in decreased expression of COL3A1 mRNA24383545
C471405sorafenibsorafenib inhibits the reaction [TGFB1 protein results in increased expression of COL3A1 protein]21360571
D013148SpironolactoneSpironolactone results in decreased expression of COL3A1 protein alternative form11300427
D013148SpironolactoneSpironolactone results in decreased expression of COL3A1 protein modified form15842549|9302344
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of COL3A1 mRNA26378955
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of COL3A1 mRNA26378955
D013629TamoxifenTamoxifen affects the expression of COL3A1 mRNA14699072
D013629TamoxifenTamoxifen affects the expression of COL3A1 mRNA20937368
D013739TestosteroneTestosterone results in increased expression of COL3A1 mRNA21475673
D013739TestosteroneTestosterone results in increased expression of COL3A1 protein modified form21475673
D013739TestosteroneTestosterone affects the expression of COL3A1 mRNA20403060
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of COL3A1 mRNA]20032058
C004648testosterone enanthatetestosterone enanthate affects the expression of COL3A1 mRNA17440010
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of COL3A1 mRNA]14728982
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of COL3A1 mRNA21570461|2637764
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [EGF protein results in increased expression of COL3A1 mRNA]15667827
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of COL3A1 mRNA24035824
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of COL3A1 mRNA14728982|2771310
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of COL3A1 mRNA15644576|2095900
C017953tetramethylpyrazineNFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]]27477297
C017953tetramethylpyrazinetetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein]27477297
D013853Thioacetamide"Drugs, Chinese Herbal inhibits the reaction [Thioacetamide results in increased expression of COL3A1 mRNA]"17629604
D013853ThioacetamideLipopolysaccharides inhibits the reaction [Thioacetamide results in increased expression of COL3A1 mRNA]17621560
D013853ThioacetamideThioacetamide results in increased expression of COL3A1 mRNA17621560|1762960
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of COL3A1 protein22761892
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of COL3A1 mRNA22761892|2811129
D019772TopotecanCOL3A1 mRNA results in decreased susceptibility to Topotecan25199881
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of COL3A1 mRNA25729387
D019772TopotecanTopotecan results in increased expression of COL3A1 mRNA25729387
D014112ToxapheneToxaphene results in increased expression of COL3A1 mRNA23153324
D014118Toxins, Biological"Toxins, Biological affects the expression of COL3A1 mRNA"19682533
D014212TretinoinTretinoin results in increased expression of COL3A1 mRNA21934132
D014212TretinoinTretinoin results in increased expression of COL3A1 protein1708081
D014212TretinoinTretinoin inhibits the reaction [AGT protein results in increased secretion of COL3A1 protein]16539842
D014241Trichloroethylene[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of COL3A1 mRNA17905399
C012589trichostatin Atrichostatin A results in increased expression of COL3A1 mRNA23463510
C012589trichostatin Atrichostatin A results in decreased expression of COL3A1 mRNA15901671
D014403TubocurarineTubocurarine results in decreased expression of COL3A1 mRNA19728367
D017973Tungsten CompoundsTungsten Compounds results in decreased expression of COL3A1 mRNA28666766
C113580U 0126U 0126 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL3A1 mRNA]28987794
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of COL3A1 mRNA18479249
D014635Valproic AcidValproic Acid affects the expression of COL3A1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of COL3A1 mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of COL3A1 mRNA24896083
D014635Valproic AcidValproic Acid results in decreased expression of COL3A1 mRNA15901671
C066075vanadium pentoxidevanadium pentoxide results in decreased expression of COL3A1 mRNA17459161
D014640VancomycinVancomycin results in decreased expression of COL3A1 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of COL3A1 gene25560391
C025643vinclozolinvinclozolin affects the expression of COL3A1 mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of COL3A1 mRNA23034163
D014750VincristineCOL3A1 mRNA results in decreased susceptibility to Vincristine25199881
C029297vinylidene chloridevinylidene chloride results in increased expression of COL3A1 mRNA26682919
C111237vorinostatvorinostat results in decreased expression of COL3A1 mRNA20060208
D015032ZincZinc deficiency results in increased expression of COL3A1 mRNA18356318
C088658zoledronic acidFenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]28871336
C088658zoledronic acidzoledronic acid results in increased expression of COL3A1 mRNA28871336

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0002020protease binding-IPI19932771  
GO:0005178integrin binding-IMP9573018  
GO:0005178integrin binding-NAS14970208  
GO:0005201extracellular matrix structural constituent-IBA21873635  
GO:0005201extracellular matrix structural constituent-IMP7487954  9036918  
GO:0005515protein binding-IPI2839553  16754721  16912226  20015075  
GO:0030020extracellular matrix structural constituent conferring tensile strength-HDA27559042  
GO:0046332SMAD binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO:0048407platelet-derived growth factor binding-IDA8900172  
GO ID GO Term Qualifier Evidence PubMed
GO:0001501skeletal system development-IEA-  
GO:0007160cell-matrix adhesion-IDA16912226  
GO:0007179transforming growth factor beta receptor signaling pathway-IDA16360482  
GO:0007229integrin-mediated signaling pathway-IMP14970208  
GO:0007507heart development-IMP7546986  
GO:0007568aging-IEA-  
GO:0009314response to radiation-IDA14736764  
GO:0009612response to mechanical stimulus-IEA-  
GO:0018149peptide cross-linking-IDA16754721  
GO:0021987cerebral cortex development-ISS-  
GO:0030168platelet activation-NAS9573018  
GO:0030198extracellular matrix organization-IBA21873635  
GO:0030198extracellular matrix organization-TAS-  
GO:0030199collagen fibril organization-IMP7546986  9036918  
GO:0030199collagen fibril organization-NAS1672129  
GO:0034097response to cytokine-IDA9076960  16360482  
GO:0035025positive regulation of Rho protein signal transduction-ISS-  
GO:0042060wound healing-IDA1466622  
GO:0042060wound healing-NAS14736764  
GO:0043588skin development-IMP9036918  
GO:0048565digestive tract development-IEA-  
GO:0050776regulation of immune response-TAS-  
GO:0050777negative regulation of immune response-IMP16754721  
GO:0060414aorta smooth muscle tissue morphogenesis-IEA-  
GO:0071230cellular response to amino acid stimulus-IEA-  
GO:0097435supramolecular fiber organization-IMP14970208  
GO:2001223negative regulation of neuron migration-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-HDA27068509  
GO:0005576extracellular region-TAS-  
GO:0005586collagen type III trimer-IBA21873635  
GO:0005586collagen type III trimer-IDA19932771  
GO:0005586collagen type III trimer-IMP7487954  17576241  
GO:0005586collagen type III trimer-NAS1672129  
GO:0005615extracellular space-IBA21873635  
GO:0005615extracellular space-IDA7487954  
GO:0005615extracellular space-NAS9036918  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0031012extracellular matrix-IMP7487954  14970208  
GO:0062023collagen-containing extracellular matrix-HDA27559042  
GO:0062023collagen-containing extracellular matrixcolocalizes_withTAS22261194  
KEGG ID KEGG Term
hsa04510Focal adhesion
hsa04512ECM-receptor interaction
hsa04974Protein digestion and absorption
hsa05146Amoebiasis
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyTAS
R-HSA-1280218Adaptive Immune SystemTAS
R-HSA-1442490Collagen degradationIEA
R-HSA-1442490Collagen degradationTAS
R-HSA-1474228Degradation of the extracellular matrixIEA
R-HSA-1474228Degradation of the extracellular matrixTAS
R-HSA-1474244Extracellular matrix organizationIEA
R-HSA-1474244Extracellular matrix organizationTAS
R-HSA-1474290Collagen formationTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1650814Collagen biosynthesis and modifying enzymesTAS
R-HSA-168256Immune SystemTAS
R-HSA-186797Signaling by PDGFTAS
R-HSA-198933Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellTAS
R-HSA-2022090Assembly of collagen fibrils and other multimeric structuresTAS
R-HSA-216083Integrin cell surface interactionsTAS
R-HSA-2173782Binding and Uptake of Ligands by Scavenger ReceptorsIEA
R-HSA-3000170Syndecan interactionsIEA
R-HSA-3000171Non-integrin membrane-ECM interactionsTAS
R-HSA-3000171Non-integrin membrane-ECM interactionsIEA
R-HSA-3000178ECM proteoglycansTAS
R-HSA-3000178ECM proteoglycansIEA
R-HSA-3000480Scavenging by Class A ReceptorsIEA
R-HSA-375165NCAM signaling for neurite out-growthTAS
R-HSA-419037NCAM1 interactionsTAS
R-HSA-422475Axon guidanceTAS
R-HSA-5653656Vesicle-mediated transportIEA
R-HSA-6806834Signaling by METTAS
R-HSA-8874081MET activates PTK2 signalingTAS
R-HSA-8875878MET promotes cell motilityTAS
R-HSA-8948216Collagen chain trimerizationTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
12798348Molecular pathogenesis of subarachnoid haemorrhage. (2003 Sep)Zhang BInt J Biochem Cell Biol
21514415Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis. (2011 May)Sabo-Attwood TAm J Pathol
29614203Changes in the expression of matrix extracellular genes and TGFB family members in rotator cuff tears. (2018 Apr 3)Belangero PSJ Orthop Res
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