Gene: SPATA17

128153
IQCH|MSRG-11|MSRG11
spermatogenesis associated 17
protein-coding
1q41
Ensembl:ENSG00000162814 MIM:611032 Vega:OTTHUMG00000037875 UniprotKB:Q96L03
NC_000001.11
SNP Mapped
2   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.033e-1 (AD)  4.735e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs12759918chr1:217847795 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)
rs1567449chr1:217845614 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PEG100.694
KRBOX40.679
DCDC10.63
TTC260.618
PPIL60.618
C15orf410.616
OPRK10.615
ZBTB250.613
ALDH3A20.612
TMTC10.611

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DIO2-0.305
ETV4-0.296
FZD10-0.288
RERGL-0.287
PYGM-0.257
KLRK1-0.253
MYLK2-0.25
GPR3-0.245
IL25-0.243
REN-0.241

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of SPATA17 mRNA"25614096
D000082AcetaminophenAcetaminophen affects the expression of SPATA17 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SPATA17 mRNA22100608
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of SPATA17 gene27153756
D000638AmiodaroneAmiodarone results in increased expression of SPATA17 mRNA19774075
C547126AZM551248AZM551248 results in increased expression of SPATA17 mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of SPATA17 mRNA22228805
D004958EstradiolEGF protein promotes the reaction [Estradiol results in decreased expression of SPATA17 mRNA]24758408
D004958EstradiolEstradiol results in decreased expression of SPATA17 mRNA24758408
C006780bisphenol Abisphenol A affects the expression of SPATA17 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of SPATA17 mRNA26079696
D003471CuprizoneCuprizone results in increased expression of SPATA17 mRNA26577399
D016572CyclosporineCyclosporine results in increased expression of SPATA17 mRNA20106945
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of SPATA17 mRNA21901812
C014347decitabinedecitabine affects the expression of SPATA17 mRNA23300844
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of SPATA17 mRNA28962523
D002945CisplatinCisplatin affects the expression of SPATA17 mRNA23300844
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of SPATA17 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of SPATA17 mRNA27392435
D004041Dietary FatsDietary Fats results in increased expression of SPATA17 mRNA25016146
D004041Dietary FatsDietary Fats results in increased expression of SPATA17 mRNA21852083
D005411Flame RetardantsFlame Retardants results in increased expression of SPATA17 mRNA21901812
D017313FenretinideFenretinide results in increased expression of SPATA17 mRNA28973697
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of SPATA17 mRNA27392435
D008558MelphalanMelphalan results in decreased expression of SPATA17 mRNA22363485
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of SPATA17 mRNA28001369
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SPATA17 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SPATA17 mRNA"25554681
C046012pentanalpentanal results in decreased expression of SPATA17 mRNA26079696
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of SPATA17 mRNA25895662
D053260SootSoot results in decreased expression of SPATA17 mRNA26551751
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SPATA17 mRNA22298810
D013853ThioacetamideThioacetamide results in increased expression of SPATA17 mRNA23411599
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SPATA17 gene25560391
C111237vorinostatvorinostat results in increased expression of SPATA17 mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005516calmodulin binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal