Gene: SVOPL

136306
-
SVOP like
protein-coding
7q34
Ensembl:ENSG00000157703 MIM:611700 Vega:OTTHUMG00000155870 UniprotKB:Q8N434
NG_051552.1
SNP Mapped
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.867e-1 (AD)  3.421e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ENPP60.68
SLC16A80.623
DPYSL50.614
HS3ST50.599
AK70.593
FANCL0.588
EML10.584
PTPDC10.576
IFT800.575
KIAA1324L0.575

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZIC2-0.398
SYPL2-0.394
ZIC5-0.388
SLC2A4-0.357
RNF182-0.35
TBX15-0.333
HGF-0.331
MTRNR2L6-0.328
C4orf19-0.325
CASP7-0.323

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SVOPL mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SVOPL mRNA"27188386
C006780bisphenol Abisphenol A affects the expression of SVOPL mRNA21786754
D000069286BortezomibBortezomib results in decreased expression of SVOPL mRNA20977926
D016572CyclosporineCyclosporine results in increased methylation of SVOPL promoter27989131
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of SVOPL mRNA24317228
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SVOPL mRNA]27941970
C118739entinostatentinostat results in increased expression of SVOPL mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SVOPL mRNA"27188386
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of SVOPL mRNA26011545
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVOPL mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of SVOPL mRNA27935865
C046012pentanalpentanal results in decreased expression of SVOPL mRNA26079696
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVOPL mRNA27935865
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of SVOPL mRNA25895662
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SVOPL promoter]19654925
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of SVOPL mRNA19042947
D014635Valproic AcidValproic Acid results in increased methylation of SVOPL gene29154799
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of SVOPL mRNA27935865

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0022857transmembrane transporter activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0055085transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal