Gene: CLDN7

1366
CEPTRL2|CLDN-7|CPETRL2|Hs.84359|claudin-1
claudin 7
protein-coding
17p13.1
Ensembl:ENSG00000181885 MIM:609131 Vega:OTTHUMG00000178005 UniprotKB:O95471
NC_000017.11
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.663e-1 (AD)  1.464e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
VENTX0.774
ARL110.773
TRAF3IP30.766
CD370.765
FGD30.764
TMEM710.762
CD840.759
SIRPB20.756
MILR10.755
TLR80.749

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANKRD55-0.334
TENM3-0.332
ZNF425-0.33
C1orf53-0.329
MARCH4-0.329
SVOP-0.329
FSTL5-0.328
ENPP5-0.323
ST6GAL2-0.321
CHRNB2-0.32

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CLDN7 mRNA"18711122
C0264861,2,5,6-dibenzanthracene"[1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of CLDN7 mRNA"18711122
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CLDN7 mRNA"18711122
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in decreased expression of CLDN7 mRNA"23826121
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of CLDN7 mRNA25088246
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of CLDN7 mRNA29067470
D020106AcrylamideAcrylamide results in decreased expression of CLDN7 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CLDN7 mRNA22100608|2715375
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CLDN7 mRNA16483693
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of CLDN7 mRNA"22863853
D001151ArsenicArsenic results in increased expression of CLDN7 mRNA24349408
D001151ArsenicArsenic affects the localization of CLDN7 protein24349408
C006632arsenic trioxideCLDN7 protein results in decreased susceptibility to arsenic trioxide20707922
C015001arsenitearsenite results in decreased methylation of CLDN7 promoter23974009
D001241AspirinAspirin results in increased expression of CLDN7 mRNA12800193
C487081belinostatbelinostat results in increased expression of CLDN7 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CLDN7 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CLDN7 mRNA22228805
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CLDN7 mRNA"18711122
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of CLDN7 mRNA18711122
D004958EstradiolEstradiol affects the expression of CLDN7 mRNA15598610
D004958EstradiolEstradiol results in increased expression of CLDN7 mRNA14664709|1528915
C095105bexarotenebexarotene results in increased expression of CLDN7 mRNA16648578
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CLDN7 mRNA28628672
C006780bisphenol Abisphenol A affects the expression of CLDN7 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of CLDN7 mRNA18180321
C584509C646 compoundC646 compound results in increased expression of CLDN7 mRNA26191083
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLDN7 mRNA20360939
D002220CarbamazepineCarbamazepine affects the expression of CLDN7 mRNA25979313
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLDN7 mRNA20938992
D016572CyclosporineCyclosporine results in increased expression of CLDN7 mRNA27989131
D016572CyclosporineCyclosporine results in increased expression of CLDN7 mRNA21865292
C014347decitabinedecitabine inhibits the reaction [Smoke results in decreased expression of CLDN7 mRNA]21095227
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CLDN7 mRNA28628672
C041517dibenzo(a,l)pyrene"[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CLDN7 mRNA"18711122
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of CLDN7 mRNA27392435
D002945CisplatinCisplatin results in increased expression of CLDN7 mRNA27392435
D002945CisplatinCLDN7 protein results in decreased susceptibility to Cisplatin21134740
D004026DieldrinDieldrin results in increased expression of CLDN7 mRNA20438755
D004041Dietary FatsDietary Fats results in decreased expression of CLDN7 mRNA25016146
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CLDN7 mRNA24535843
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CLDN7 mRNA18164116
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CLDN7 mRNA20360939
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CLDN7 mRNA25242112
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CLDN7 mRNA14664709|1528915
D002117CalcitriolCalcitriol results in increased expression of CLDN7 mRNA26485663
C118739entinostatentinostat results in increased expression of CLDN7 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CLDN7 mRNA22079256
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CLDN7 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CLDN7 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CLDN7 mRNA15834898|1755790
D005419FlavonoidsFlavonoids results in decreased expression of CLDN7 mRNA18035473
C007738fluoranthene"[1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of CLDN7 mRNA"18711122
C007738fluoranthene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of CLDN7 mRNA18711122
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CLDN7 mRNA17187413
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLDN7 mRNA20938992
C039281furanfuran results in increased expression of CLDN7 mRNA27387713
D019833GenisteinGenistein results in increased expression of CLDN7 mRNA15289156
D017313FenretinideFenretinide results in increased expression of CLDN7 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CLDN7 mRNA18661270
C492448ICG 001ICG 001 results in increased expression of CLDN7 mRNA26191083
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CLDN7 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of CLDN7 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of CLDN7 mRNA27392435
C544151jinfukangjinfukang results in increased expression of CLDN7 mRNA27392435
C045463leflunomideleflunomide results in decreased expression of CLDN7 mRNA28988120
C042720mercuric bromidemercuric bromide results in increased expression of CLDN7 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CLDN7 mRNA20938992
D008727MethotrexateMethotrexate results in increased expression of CLDN7 mRNA21678067
D008727MethotrexateMethotrexate affects the expression of CLDN7 mRNA18502557
D008770MethylnitrosoureaMethylnitrosourea results in decreased expression of CLDN7 mRNA16525678
C523799MRK 003CLDN7 results in decreased susceptibility to MRK 00319903844
D009151Mustard GasMustard Gas results in increased expression of CLDN7 mRNA25102026
D009532NickelNickel results in decreased expression of CLDN7 mRNA25583101
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of CLDN7 mRNA26272509
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CLDN7 mRNA26272509
C014153pirimiphos methylpirimiphos methyl results in increased expression of CLDN7 mRNA27845199
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CLDN7 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of CLDN7 mRNA12832660
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CLDN7 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CLDN7 mRNA22079256
D011374ProgesteroneProgesterone results in decreased expression of CLDN7 mRNA23018184
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CLDN7 mRNA25895662
D020123SirolimusSirolimus results in increased expression of CLDN7 mRNA21865292
D012906Smokedecitabine inhibits the reaction [Smoke results in decreased expression of CLDN7 mRNA]21095227
D012906SmokeSmoke results in decreased expression of CLDN7 mRNA21095227
C017947sodium arsenitesodium arsenite results in increased expression of CLDN7 mRNA24349408
C017947sodium arsenitesodium arsenite affects the localization of CLDN7 protein24349408
C016104sodium bichromatesodium bichromate results in decreased expression of CLDN7 mRNA22561333
D016559TacrolimusTacrolimus results in increased expression of CLDN7 mRNA21865292
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CLDN7 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CLDN7 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CLDN7 mRNA27913140
D013853ThioacetamideThioacetamide results in increased expression of CLDN7 mRNA23411599
C009495titanium dioxidetitanium dioxide results in increased expression of CLDN7 mRNA23409001
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CLDN7 mRNA27404394
D014212TretinoinTretinoin results in increased expression of CLDN7 mRNA16236135
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of CLDN7 mRNA24935251|2627250
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CLDN7 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CLDN7 mRNA23179753|2352703
D014640VancomycinVancomycin results in decreased expression of CLDN7 mRNA18930951
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CLDN7 mRNA"27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005198structural molecule activity-IEA-  
GO:0005515protein binding-IPI16054130  20651236  25416956  
GO:0042802identical protein binding-ISS-  
GO:0050839cell adhesion molecule binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007162negative regulation of cell adhesion-IEA-  
GO:0008284positive regulation of cell proliferation-IEA-  
GO:0016338calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules-ISS-  
GO:0032463negative regulation of protein homooligomerization-IEA-  
GO:0043066negative regulation of apoptotic process-IEA-  
GO:0045471response to ethanol-IEA-  
GO:2000147positive regulation of cell motility-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-IDA20375010  
GO:0005923bicellular tight junction-ISS-  
GO:0016021integral component of membrane-IEA-  
GO:0016323basolateral plasma membrane-IEA-  
GO:0016327apicolateral plasma membrane-IEA-  
GO:0016328lateral plasma membrane-IEA-  
KEGG ID KEGG Term
hsa04514Cell adhesion molecules (CAMs)
hsa04530Tight junction
hsa04670Leukocyte transendothelial migration
hsa05160Hepatitis C
Reactome ID Reactome Term Evidence
R-HSA-1500931Cell-Cell communicationIEA
R-HSA-420029Tight junction interactionsIEA
R-HSA-421270Cell-cell junction organizationIEA
R-HSA-446728Cell junction organizationIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27687058Claudin-1 Protein Expression Is a Good Prognostic Factor in Non-Small Cell Lung Cancer, but only in Squamous Cell Carcinoma Cases. (2017 Jan)Moldvay JPathol Oncol Res