Gene: SGCZ

137868
ZSG1
sarcoglycan zeta
protein-coding
8p22
Ensembl:ENSG00000185053 MIM:608113 Vega:OTTHUMG00000090827 UniprotKB:Q96LD1
NG_008899.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.129e-1 (AD)  6.289e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TENM10.605
C8orf340.591
SLC25A150.575
COL19A10.568
SLC9A70.566
COL25A10.566
KIAA10240.562
NXPH20.559
GRIN3A0.557
TACR10.554

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CSAG1-0.344
PPBP-0.316
CDA-0.314
ATOH8-0.311
FXYD3-0.307
ROM1-0.302
CLEC4E-0.298
WDR38-0.295
HRASLS2-0.29
AGTRAP-0.29

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of SGCZ gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of SGCZ mRNA24449571
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SGCZ mRNA22316170
C006780bisphenol Abisphenol A results in decreased expression of SGCZ mRNA25181051
D004041Dietary FatsDietary Fats results in increased expression of SGCZ mRNA25016146
D008694MethamphetamineSGCZ gene SNP affects the susceptibility to Methamphetamine18316681
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of SGCZ mRNA"20188158
D011441PropylthiouracilPropylthiouracil results in decreased expression of SGCZ mRNA24780913
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of SGCZ gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0046716muscle cell cellular homeostasis-TAS17438352  
GO:0055001muscle cell development-TAS17438352  
GO:0060047heart contraction-IBA21873635  
GO:0061024membrane organization-TAS17438352  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IEA-  
GO:0005856cytoskeleton-IEA-  
GO:0016012sarcoglycan complex-IBA21873635  
GO:0016012sarcoglycan complex-TAS17438352  
GO:0016021integral component of membrane-IEA-  
GO:0042383sarcolemma-IBA21873635  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28957450Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium. (2017)Wang TPLoS One