Gene: DCAF4L2

138009
WDR21C
DDB1 and CUL4 associated factor 4 like 2
protein-coding
8q21.3
Ensembl:ENSG00000176566 Vega:OTTHUMG00000163767 UniprotKB:Q8NA75
NC_000008.11
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.426e-2 (AD)  7.413e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KRTAP24-10.782
OR51D10.778
OR4D110.778
ZNF7160.772
OR51F10.75
FOXI20.746
OR51S10.744
KIR2DS40.726
PITX20.71
FCRL30.702

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DBP-0.389
FUT9-0.387
ASPDH-0.384
PLA2G6-0.355
PLEKHA6-0.351
PCDH9-0.347
CYP46A1-0.34
TM7SF2-0.339
ZBTB45-0.338
ZNF835-0.338

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D018038Sodium SeleniteSodium Selenite results in decreased expression of DCAF4L2 mRNA18175754

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23512105Confirming genes influencing risk to cleft lip with/without cleft palate in a case-parent trio study. (2013 Jul)Beaty THHum Genet