Gene: PARP1

142
ADPRT|ADPRT 1|ADPRT1|ARTD1|PARP|PARP-1|PPOL|pADPRT-1
poly(ADP-ribose) polymerase 1
protein-coding
1q42.12
Ensembl:ENSG00000143799 MIM:173870 Vega:OTTHUMG00000037556 UniprotKB:P09874
NC_000001.11
PubMed|SNP Mapped
1   ANCO-SNPs
ND
9   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.627e-1 (AD)  4.039e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs3219123chr1:226367647 (GRCh38.p7)G>A / G>Tnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg17127702chr1:226594323PARP12.900e-8Smoking27651444
cg23712594chr1:226591890PARP12.180e-9Alcohol consumption der day27843151

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RMDN30.91
OSBPL20.905
CBX10.898
CNDP20.892
LAMP10.891
TSPAN30.889
ADD10.888
RNF200.884
PSAP0.883
SCRN10.883

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.81
OR4F29-0.807
C17orf112-0.277
DPPA4-0.272
FCER2-0.27
GADL1-0.263
SPRR4-0.252
KRTAP4-8-0.244
EOMES-0.24
ARHGEF35-0.24

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00277TheophyllineSmall Molecule58-55-9ApprovedTarget
DB01593ZincSmall Molecule7440-66-6Approved|InvestigationalTarget
DB02498Carba-Nicotinamide-Adenine-DinucleotideSmall MoleculeExperimentalTarget
DB02690NU1025Small Molecule90417-38-2ExperimentalTarget
DB02701NicotinamideSmall Molecule98-92-0Approved|InvestigationalTarget
DB030722-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-QuinazolinoneSmall MoleculeExperimentalTarget
DB030733-MethoxybenzamideSmall MoleculeExperimentalTarget
DB035092-(4-Chlorophenyl)-5-QuinoxalinecarboxamideSmall MoleculeExperimentalTarget
DB037223,4-Dihydro-5-Methyl-IsoquinolinoneSmall MoleculeExperimentalTarget
DB040102-(3'-Methoxyphenyl) Benzimidazole-4-CarboxamideSmall MoleculeExperimentalTarget
DB070966-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONESmall MoleculeExperimentalTarget
DB07232VeliparibSmall Molecule912444-00-9InvestigationalTarget
DB07330trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidiniumSmall MoleculeExperimentalTarget
DB077875-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONESmall MoleculeExperimentalTarget
DB09074OlaparibSmall Molecule763113-22-0ApprovedTarget
DB11793NiraparibSmall Molecule1038915-60-4Approved|InvestigationalTarget
DB12332RucaparibSmall Molecule283173-50-2Approved|InvestigationalTarget
DB13877IniparibSmall Molecule160003-66-7InvestigationalTarget
ID Drug Name Action PubMed
C55429110-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one"10-methoxy-2,2-dimethyl-2,6-dihydropyrano(3,2-c)quinolin-5-one results in increased cleavage of PARP1 protein"20833157
C55281910-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate10-(octyloxy)decyl-2-(trimethylammonium)ethyl phosphate results in increased cleavage of PARP1 protein23001822
C0067181,12-benzoperylene"1,12-benzoperylene results in increased cleavage of PARP1 protein"21132278
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of PARP1 protein"20660371|2451580
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"Glutathione inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of PARP1 protein]"24515801
C5525301,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane"NR4A1 protein inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of PARP1 protein]"20660371|2451580
C101879(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid"(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid inhibits the reaction [4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in increased cleavage of PARP1 protein]]"14535961
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased activity of PARP1 protein]"24752504
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"[1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid co-treated with Egtazic Acid] inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]"29111403
C0256031,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]"29111403
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased cleavage of PARP1 protein]"19540902
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Gallic Acid results in increased cleavage of PARP1 protein]"27060209
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]"18850067
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]"22253048
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]"21544200
C5691071-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one"1-(2-chlorobenzyl)-5'-phenyl-3'H-spiro(indoline-3,2'-(1,3,4)thiadiazol)-2-one results in increased cleavage of PARP1 protein"21903591|2382612
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]"22002103
D0140131,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]"22002103
C5822861-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea[2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein26208482
C5822861-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea"[4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein"26208482
C5524201-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane"1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of PARP1 protein"20674558
C5524201-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane"Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of PARP1 protein]"20674558
C0006039621-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]"29111459
C5696701-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one"1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one results in increased cleavage of PARP1 protein"21998291|2313619
C4164421,4-anthraquinone"1,4-anthraquinone analog results in increased cleavage of PARP1 protein"17912452
C4792341-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one"1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one inhibits the reaction [resveratrol promotes the reaction [PARP1 protein binds to YARS protein]]"25533949
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of PARP1 protein"15498850
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 results in increased cleavage of PARP1 protein"23973622
C09724015-deoxy-delta(12,14)-prostaglandin J2"[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein"23973622
C0956531,5-dihydroxyisoquinoline"1,5-dihydroxyisoquinoline inhibits the reaction [Vancomycin results in increased expression of PARP1 protein]"19833176
C0956531,5-dihydroxyisoquinoline"1,5-dihydroxyisoquinoline results in decreased expression of PARP1 protein"12824290
C0956531,5-dihydroxyisoquinoline"1,5-dihydroxyisoquinoline results in decreased activity of PARP1 protein"12824290
C07258116-hydroxycleroda-3,13(14)-dien-15,16-olide"16-hydroxycleroda-3,13(14)-dien-15,16-olide results in increased cleavage of PARP1 protein"21530604
C44865917-(dimethylaminoethylamino)-17-demethoxygeldanamycin17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]19371599
C0211831,7-dimethylxanthine"1,7-dimethylxanthine results in decreased activity of PARP1 protein"19962977
C0479481'-acetoxychavicol acetate1'-acetoxychavicol acetate promotes the reaction [TNF protein results in increased cleavage of PARP1 protein]15905586
C0364231-aminomethylphosphonic acid[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of PARP1 protein26006246
C0364231-aminomethylphosphonic acid1-aminomethylphosphonic acid results in increased cleavage of PARP1 protein23983455
C1087311'-(hydroxymethyl)eugenol1'-(hydroxymethyl)eugenol results in increased cleavage of PARP1 protein28818686
C48240220-O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol20-O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol results in increased cleavage of PARP1 protein12963989
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]"20826841
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [GDC-0973 results in increased cleavage of PARP1 protein]"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein"19411071|1958422
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"Dexamethasone promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein]"23318440
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"Doxorubicin promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein]"20826841
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[ERBB2 gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased cleavage of PARP1 protein"20453058
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"GDC-0973 promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein]"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased cleavage of PARP1 protein"20453058
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[PTEN gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased cleavage of PARP1 protein"20453058
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of PARP1 protein]25291404
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased cleavage of PARP1 protein]"15572374
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [BPDE-II results in increased cleavage of PARP1 protein]15572374
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[LM-1685 co-treated with carboxyamido-triazole] results in increased cleavage of PARP1 protein]15867384
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]14688022|2116557
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one[sodium arsenite co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in increased cleavage of PARP1 protein15028728
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]18775851
C0445652-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide2-((((2-chloroethyl)nitrosoamino)carbonyl)amino)propanamide results in increased cleavage of PARP1 protein16142332
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of PARP1 mRNA"19114083
C0787652,3,5-(triglutathion-S-yl)hydroquinone"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased activity of PARP1 protein]"24752504
C0787652,3,5-(triglutathion-S-yl)hydroquinone"[2,3,5-(triglutathion-S-yl)hydroquinone results in increased abundance of Reactive Oxygen Species] which results in increased activity of PARP1 protein"24752504|2852562
C0787652,3,5-(triglutathion-S-yl)hydroquinone"2,3,5-(triglutathion-S-yl)hydroquinone results in increased activity of PARP1 protein"24752504
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PARP1 mRNA"19167446
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of PARP1 protein"16884709
C0098282,4,5,2',5'-pentachlorobiphenyl"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein]"20840854
C5622542'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione"2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased cleavage of PARP1 protein"21741372
C5614542,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide"2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide results in decreased phosphorylation of PARP1 protein"21464613
C5614542,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide"2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide results in increased cleavage of PARP1 protein"21464613
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]14640974
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FAM168A results in decreased susceptibility to Cisplatin]] which results in increased cleavage of PARP1 protein23251525
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased cleavage of PARP1 protein]27032576
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased cleavage of PARP1 protein14688022|2038698
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[TNFSF10 protein co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in increased cleavage of PARP1 protein19261616
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]23143138
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]14724571
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
C0094072,5,2',5'-tetrachlorobiphenyl"2,5,2',5'-tetrachlorobiphenyl results in increased activity of PARP1 protein"19433264
C0094072,5,2',5'-tetrachlorobiphenyl"[2,5,2',5'-tetrachlorobiphenyl results in increased activity of PARP1 protein] which results in decreased abundance of NAD"19433264
C4882882,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid"[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of PARP1 protein"18444175
C4882882,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid"2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid results in increased cleavage of PARP1 protein"18444175
C1177762,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone"2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in increased cleavage of PARP1 protein"26630137
C5066982,5-dimethylcelecoxib"2,5-dimethylcelecoxib results in increased cleavage of PARP1 protein"16123214|1848522
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased activity of PARP1 protein"17072025
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"2-amino-3,4-dimethylimidazo(4,5-f)quinoline results in decreased activity of PARP1 protein"17072025
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in decreased activity of PARP1 protein"17072025
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"2-amino-3-methyl-9H-pyrido(2,3-b)indole results in decreased activity of PARP1 protein"17072025
C0292162-amino-3-methylimidazo(4,5-f)quinoline"2-amino-3-methylimidazo(4,5-f)quinoline results in decreased activity of PARP1 protein"17072025
C0237852-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole results in decreased activity of PARP1 protein"17072025
C5706622-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one"2-amino-8-(4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido(2,3-d)pyrimidin-7(8H)-one results in increased cleavage of and results in increased activity of PARP1 protein"23639247
C0178222-amino-9H-pyrido(2,3-b)indole"2-amino-9H-pyrido(2,3-b)indole results in decreased activity of PARP1 protein"17072025
C4843272'-benzoyloxycinnamaldehyde2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein14660655
C4843272'-benzoyloxycinnamaldehydeAcetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein]14660655
C4843272'-benzoyloxycinnamaldehydeGlutathione inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein]14660655
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased activity of PARP1 protein26383632
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of PARP1 protein20840853
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of PARP1 protein modified form20469912
C0312782-chloroethyl ethyl sulfidePARP1 protein affects the susceptibility to 2-chloroethyl ethyl sulfide19111594
C0312782-chloroethyl ethyl sulfide2-chloroethyl ethyl sulfide results in increased expression of PARP1 protein modified form20469912
C5188602-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide"2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid ethyl amide results in increased cleavage of PARP1 protein"17363558
C4362842-cyclopentyl-5-(5-isoquinolylsulfonyl)-6-nitro-1H-benzo(D)imidazole2-cyclopentyl-5-(5-isoquinolylsulfonyl)-6-nitro-1H-benzo(D)imidazole results in decreased cleavage of PARP1 protein11478917
C4923222-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole"2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]"22155090
C0005952302-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one"2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one results in decreased activity of PARP1 protein"27704718
C0228302-methoxyestradiol2-methoxyestradiol results in increased expression of PARP1 protein modified form23967052
C5003442-methoxyestradiol-3,17-bis-O,O-sulfamate"2-methoxyestradiol-3,17-bis-O,O-sulfamate results in increased cleavage of PARP1 protein"15258464
C4437592-methylarachidonyl-2'-fluoroethylamide2-methylarachidonyl-2'-fluoroethylamide results in increased cleavage of PARP1 protein19509271
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one[2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein26208482
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-onePARP1 protein affects the reaction [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein]16556909
C4958182-morpholin-4-yl-6-thianthren-1-yl-pyran-4-onePARP1 protein affects the susceptibility to 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one16556909
C4792352-(morpholin-4-yl)benzo(h)chromen-4-onePARP1 protein affects the reaction [2-(morpholin-4-yl)benzo(h)chromen-4-one results in decreased activity of PRKDC protein]16556909
C4792352-(morpholin-4-yl)benzo(h)chromen-4-onePARP1 protein affects the susceptibility to 2-(morpholin-4-yl)benzo(h)chromen-4-one16556909
C5561683-(2-(3-(1-adamantyl)-4-hydroxyphenyl)-5-pyrimidinyl)-2-propenoic acid3-(2-(3-(1-adamantyl)-4-hydroxyphenyl)-5-pyrimidinyl)-2-propenoic acid results in increased cleavage of PARP1 protein21548569
C1096023-(2-(4-(3-chloro-2-methylphenyl)1-piperazinyl)ethyl)5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazol dihydrochloride 3.5 hydrate"3-(2-(4-(3-chloro-2-methylphenyl)1-piperazinyl)ethyl)5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazol dihydrochloride 3.5 hydrate results in decreased cleavage of PARP1 protein"16987238
C4175203-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione"3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]"22155090
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of PARP1 protein"16580691
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl results in increased activity of PARP1 protein"19433264
C0284513,4,3',4'-tetrachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl results in increased activity of PARP1 protein] which results in decreased abundance of NAD"19433264
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein]"20840854
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PARP1 protein"16884709
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PARP1 mRNA"23196670
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in increased expression of PARP1 protein modified form"23770989
C0454213,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in decreased activity of PARP1 protein"17072025
C513485(3-(4-(bis(2-chloroethyl)amino)phenyl)-3-propyl)carbamic acid 2-(6-(17-hydroxy-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-11-yl)hexylamino)ethyl ester"(3-(4-(bis(2-chloroethyl)amino)phenyl)-3-propyl)carbamic acid 2-(6-(17-hydroxy-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta(a)phenanthren-11-yl)hexylamino)ethyl ester results in increased cleavage of PARP1 protein"16039525
C1087293,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]"17237268
C1087293,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone results in decreased activity of PARP1 protein"15486061
C1087293,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone results in decreased activity of PARP1 protein"14769338|2141734
C0282883',4'-dihydroxyflavone"3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]"16014620
C0282883',4'-dihydroxyflavone"3',4'-dihydroxyflavone analog inhibits the reaction [kaempferol results in increased cleavage of PARP1 protein]"16014620
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile[3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [FAM168A results in decreased susceptibility to Cisplatin]] which results in increased cleavage of PARP1 protein23251525
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [hydroxyethyl methacrylate results in increased cleavage of PARP1 protein]28184909
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile results in increased cleavage of and results in increased activity of PARP1 protein16173963
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile[Apigenin co-treated with 3-(4-methylphenylsulfonyl)-2-propenenitrile] results in increased cleavage of PARP1 protein24148603
C0178563,5-diaminobenzoic acid"3,5-diaminobenzoic acid analog results in increased cleavage of PARP1 protein"23499788
C0191323-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in decreased activity of PARP1 protein"17072025
C0191323-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of PARP1 protein"11999409
C0191323-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of PARP1 protein]"11999409
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"3-amino-1-methyl-5H-pyrido(4,3-b)indole results in decreased activity of PARP1 protein"17072025
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"3-amino-1-methyl-5H-pyrido(4,3-b)indole results in increased activity of PARP1 protein"17072025
C0251603-aminobenzamide"3-aminobenzamide inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]"11217149
C0251603-aminobenzamide"3-aminobenzamide inhibits the reaction [Asbestos, Crocidolite results in increased activity of PARP1 protein]"21543585
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]2120135|2126186
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form]22226932
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]11217149
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]26047893
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Lithocholic Acid analog results in increased activity of PARP1 protein]2120135
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [mezerein results in increased activity of PARP1 protein]2120135
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]]20493934
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Smoke analog results in increased activity of PARP1 protein]11217149
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2120135|2126186
C0251603-aminobenzamide3-aminobenzamide promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
C0251603-aminobenzamide3-aminobenzamide promotes the reaction [Capsaicin results in increased expression of PARP1 protein]22226932
C0251603-aminobenzamide3-aminobenzamide results in decreased activity of PARP1 protein15670817|1766960
C0251603-aminobenzamide[3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
C0251603-aminobenzamide[3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
C0251603-aminobenzamide[3-aminobenzamide results in decreased activity of PARP1 protein] which results in increased susceptibility to Cisplatin21399878
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to Acetaminophen]15601672
C0251603-aminobenzamide3-aminobenzamide results in decreased activity of PARP1 protein27026705
C0251603-aminobenzamide3-aminobenzamide results in decreased activity of PARP1 protein12824290|1788499
C4167823-bromoacetylamino benzoic acid ethyl ester3-bromoacetylamino benzoic acid ethyl ester results in increased cleavage of PARP1 protein11077052
C0179063-dinitrobenzene3-dinitrobenzene results in increased cleavage of PARP1 protein19477251
C0179063-dinitrobenzenepyrazolanthrone inhibits the reaction [3-dinitrobenzene results in increased cleavage of PARP1 protein]19477251
C5542893-hydroxylup-20(29)-ene-27,28-dioic acid dimethyl ester"3-hydroxylup-20(29)-ene-27,28-dioic acid dimethyl ester results in increased cleavage of PARP1 protein"20670616
C0005885823-methoxy-6-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-2-amine"3-methoxy-6-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridin-2-amine results in increased cleavage of PARP1 protein"24471873
C0259463-methyladenine[3-methyladenine co-treated with Amiodarone] results in increased cleavage of PARP1 protein23912912
C0259463-methyladenine[3-methyladenine co-treated with fosbretabulin] results in increased cleavage of PARP1 protein24321340
C0259463-methyladenine3-methyladenine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein]24875536
C0259463-methyladenine3-methyladenine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
C0259463-methyladenine3-methyladenine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein]24875536
C0259463-methyladenine3-methyladenine inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
C0259463-methyladenine3-methyladenine inhibits the reaction [resveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]21778691
C0259463-methyladenine3-methyladenine promotes the reaction [BO-1012 results in increased cleavage of PARP1 protein]24823293
C0259463-methyladenine3-methyladenine promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
C0259463-methyladenine3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein]19116755
C0259463-methyladenine3-methyladenine promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]24321340
C0259463-methyladenine3-methyladenine results in increased cleavage of PARP1 protein21616090
C0259463-methyladenine3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein]19116755
C0259463-methyladenine3-methyladenine inhibits the reaction [aristolochic acid I results in increased cleavage of PARP1 protein]23939141
C0473683-methylquercetin3-methylquercetin results in increased cleavage of PARP1 protein22992727
C0336433-nitrofluoranthene3-nitrofluoranthene results in increased cleavage of PARP1 protein19041363
C0339013'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased expression of PARP1 protein22253048
C5810043-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile"3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein"24036456
C5810043-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile"Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
C5810043-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile"Glutathione inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
C5810043-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile"pyrazolanthrone inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
C5810043-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile"SB 203580 inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
C0006147253'-oxomethylisoeugenol3'-oxomethylisoeugenol results in increased cleavage of PARP1 protein28818686
C4967514-(1H-imidazol-1-yl)retinoic acid4-(1H-imidazol-1-yl)retinoic acid results in increased cleavage of PARP1 protein17387344
C4711094(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline"4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline results in increased cleavage of PARP1 protein"23219847
C4711094(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline"4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]"23143138
C0006020014-(3,5-dimethoxystyryl)phenyl acetate"4-(3,5-dimethoxystyryl)phenyl acetate results in increased cleavage of PARP1 protein"26138072
C0888604-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline results in increased cleavage of PARP1 protein"22493441
C5729614-(4-(3-(4-trifluoromethoxy-phenyl)ureido)cyclohexyloxy)benzoic acid4-(4-(3-(4-trifluoromethoxy-phenyl)ureido)cyclohexyloxy)benzoic acid results in decreased cleavage of PARP1 protein25377915
C5174874-(4-bromophenyl)-2,3-dihydro-N,3-bis(3,4,5-trimethoxyphenyl)-2-oxoidmi-dazole-1-carboxamide"4-(4-bromophenyl)-2,3-dihydro-N,3-bis(3,4,5-trimethoxyphenyl)-2-oxoidmi-dazole-1-carboxamide results in increased cleavage of PARP1 protein"16900371
C5546804-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide results in increased degradation of PARP1 protein20446019
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of PARP1 mRNA"18648102
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C5688624-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline"4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in increased cleavage of PARP1 protein"24161432
C0865384-amino-1,8-naphthalimide"4-amino-1,8-naphthalimide inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein]"15456408
C0865384-amino-1,8-naphthalimide"4-amino-1,8-naphthalimide results in decreased expression of PARP1 protein"25499136
C0865384-amino-1,8-naphthalimide"4-amino-1,8-naphthalimide results in decreased activity of PARP1 protein"16556909
C0865384-amino-1,8-naphthalimide"ATM protein affects the reaction [4-amino-1,8-naphthalimide results in decreased activity of PARP1 protein]"16556909
C0865384-amino-1,8-naphthalimide"PARP1 protein affects the reaction [4-amino-1,8-naphthalimide results in increased phosphorylation of ATM protein]"16556909
C0865384-amino-1,8-naphthalimide"PARP1 protein affects the reaction [4-amino-1,8-naphthalimide results in increased phosphorylation of CHEK2 protein]"16556909
C0865384-amino-1,8-naphthalimide"PRKDC protein affects the reaction [4-amino-1,8-naphthalimide results in decreased activity of PARP1 protein]"16556909
C0865384-amino-1,8-naphthalimide"4-amino-1,8-naphthalimide results in decreased activity of PARP1 protein"14769338
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of PARP1 mRNA"21346803
C0553314-aminocrotonic acid"(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid inhibits the reaction [4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in increased cleavage of PARP1 protein]]"14535961
C0553314-aminocrotonic acid4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in increased cleavage of PARP1 protein]14535961
C4756224-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine"[4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein"26208482
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased degradation of PARP1 protein11488593
C5843684'-methoxy licoflavanone4'-methoxy licoflavanone results in increased cleavage of PARP1 protein23850732
C4988264-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased cleavage of PARP1 protein26549707
C4988264-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamidebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased cleavage of PARP1 protein]26549707
C4988264-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamidebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased cleavage of PARP1 protein]26549707
C0757734-phenylbutyric acid4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]27634458
C0757734-phenylbutyric acid4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of PARP1 protein modified form]27578021
C4664205,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride"5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [Oxidopamine results in increased activity of PARP1 protein]"21397656
C4927215,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III)"5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein]"19286953
C5031195-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased cleavage of PARP1 protein15831436
C1109625,6-dichlorobenzimidazole"5,6-dichlorobenzimidazole promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]"15688023
C0806695,7-dihydroxy-6-methoxy-2-phenylchromen-4-one"5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased degradation of PARP1 protein"19135124
C4114255-aminoisoquinolinone5-aminoisoquinolinone inhibits the reaction [PARP1 protein results in increased susceptibility to Acetaminophen]15601672
C4114255-aminoisoquinolinone5-aminoisoquinolinone results in decreased activity of PARP1 protein21417348
C5582885-methylselenylmethyl-2'-deoxyuridine"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]"22002103
C5582885-methylselenylmethyl-2'-deoxyuridine5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein22002103
C5582885-methylselenylmethyl-2'-deoxyuridineAcetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
C5582885-methylselenylmethyl-2'-deoxyuridineQuercetin inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
C5582895-phenylselenylmethyl-2'-deoxyuridine"1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]"22002103
C5582895-phenylselenylmethyl-2'-deoxyuridine5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein22002103
C5582895-phenylselenylmethyl-2'-deoxyuridineAcetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
C5582895-phenylselenylmethyl-2'-deoxyuridineQuercetin inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
C5762686-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide"6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased cleavage of PARP1 protein"27720946
C5762686-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide"AKT1 protein inhibits the reaction [6-(3,4-dihydro-1H-isoquinolin-2-yl)-N-(6-methylpyridin-2-yl)nicotinamide analog results in increased cleavage of PARP1 protein]"27720946
C5715326-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid6-(3-cyclopentyl-2-(4-(trifluoromethyl)-1H-imidazol-1-yl)propanamido)nicotinic acid results in increased cleavage of PARP1 protein25316768
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]"26887594
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased cleavage of PARP1 protein"23274516
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"TP53 mutant form inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased cleavage of PARP1 protein]"23274516
C5847556-bromo-8-ethoxy-3-nitro-2H-chromene6-bromo-8-ethoxy-3-nitro-2H-chromene results in increased cleavage of PARP1 protein24831963
C5847556-bromo-8-ethoxy-3-nitro-2H-chromenePTEN protein inhibits the reaction [6-bromo-8-ethoxy-3-nitro-2H-chromene results in increased cleavage of PARP1 protein]24831963
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of PARP1 protein modified form]28414160
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]"24726431
C5505476-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Camptothecin results in increased cleavage of PARP1 protein]"24726431
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc results in decreased expression of PARP1 protein]"16799065
C0106436-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein]"16799065
C5306306(hydroxymethyl)-1,4-anthracenedione"6(hydroxymethyl)-1,4-anthracenedione results in increased cleavage of PARP1 protein"17912452
C0538766-isopropoxy-9-oxoxanthene-2-carboxylic acid[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased cleavage of and results in increased activity of PARP1 protein19407222
C5538177-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in decreased expression of PARP1 mRNA"19936915
C5538177-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one"7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in increased expression of PARP1 protein modified form"19936915
C5591457-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine"7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine results in increased cleavage of PARP1 protein"21417417
C0548527-hydroxystaurosporine[alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of PARP1 protein16012789
C0030017-ketocholesterol7-ketocholesterol results in increased cleavage of PARP1 protein25845326
C0030017-ketocholesterolAcetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]25845326
C0030017-ketocholesterolBAY 11-7085 inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]25845326
C0030017-ketocholesterolquercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]25845326
C5228037-monohydroxyethylrutoside7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17285121
C5228037-monohydroxyethylrutoside7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17285121
C5571208-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene results in increased cleavage of PARP1 protein24831963
C5568018-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione"8-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]"20946892
C5568018-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione"8-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]"20946892
C0371129-deoxy-delta-9-prostaglandin D29-deoxy-delta-9-prostaglandin D2 results in increased cleavage of PARP1 protein15843042
C0371129-deoxy-delta-9-prostaglandin D2"[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein"23973622
C512352abexinostat[Bortezomib co-treated with abexinostat] results in increased activity of PARP1 protein19417023
C496492abrineabrine results in increased cleavage of PARP1 protein23788630
C496492abrineabrine results in increased cleavage of PARP1 protein23788630
C042553acenaphthyleneacenaphthylene results in increased cleavage of PARP1 protein21132278
D000082AcetaminophenAcetaminophen results in decreased expression of PARP1 mRNA21420995
D000082AcetaminophenAcetaminophen results in increased cleavage of PARP112005112
D000082AcetaminophenAcetaminophen results in increased cleavage of PARP1 protein14725611
D000082Acetaminophen3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to Acetaminophen]15601672
D000082Acetaminophen5-aminoisoquinolinone inhibits the reaction [PARP1 protein results in increased susceptibility to Acetaminophen]15601672
D000082AcetaminophenAcetaminophen results in increased activity of PARP1 protein15601672
D000082AcetaminophenPARP1 protein results in increased susceptibility to Acetaminophen15601672
D000082AcetaminophenAcetaminophen results in increased expression of PARP1 mRNA16751229
C043377acetochlor2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of PARP1 protein]25291404
C043377acetochloracetochlor results in increased cleavage of PARP1 protein25291404
C056165acetovanilloneacetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]29111459
C056165acetovanilloneacetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]18509044
C094432acetyl-11-ketoboswellic acidacetyl-11-ketoboswellic acid results in increased cleavage of PARP1 protein20692244
C099158acetyl-aspartyl-glutamyl-valyl-aspartalacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]27106530
C099158acetyl-aspartyl-glutamyl-valyl-aspartalacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of PARP1 protein]12482751
C099158acetyl-aspartyl-glutamyl-valyl-aspartalacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C487680acetylbritannilatoneacetylbritannilatone analog results in increased cleavage of PARP1 protein27262408
C487680acetylbritannilatonebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [acetylbritannilatone analog results in increased cleavage of PARP1 protein]27262408
C487680acetylbritannilatoneTP53 protein affects the reaction [acetylbritannilatone analog results in increased cleavage of PARP1 protein]27262408
D000111Acetylcysteine[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]24100277
D000111AcetylcysteineAcetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]25824409
D000111AcetylcysteineAcetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein]14660655
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
D000111AcetylcysteineAcetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
D000111AcetylcysteineAcetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]27634458
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]17237268
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25246272
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of PARP1 protein]25972196
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]18703135
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]15496615
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]]22172632
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]22172632
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]27106530
D000111AcetylcysteineAcetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]22578287
D000111AcetylcysteineAcetylcysteine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein]24875536
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000111AcetylcysteineAcetylcysteine inhibits the reaction [manumycin results in increased cleavage of PARP1]19409983
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein]24875536
D000111AcetylcysteineAcetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]]22172632
D000111AcetylcysteineAcetylcysteine inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]22172632
D000111AcetylcysteineAcetylcysteine inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]26887594
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
D000111AcetylcysteineAcetylcysteine inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]28237877
D000111AcetylcysteineAcetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased cleavage of PARP1 protein]25246272
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]25940438
D000111AcetylcysteineAcetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein]28918123
D000111AcetylcysteineAcetylcysteine inhibits the reaction [shikonin results in increased cleavage of PARP1 protein]24463199
D000111AcetylcysteineAcetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
D000111AcetylcysteineAcetylcysteine inhibits the reaction [shogaol results in increased cleavage of PARP1 protein]18384088
D000111AcetylcysteineAcetylcysteine inhibits the reaction [sinularin results in increased cleavage of PARP1 protein]28548367
D000111AcetylcysteineAcetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]19536524
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[sulforafan co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]22922937
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]18281123
D000111AcetylcysteineAcetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]29111459
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]25034532
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]26203587
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of PARP1 protein modified form]23711929
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein]19679660
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]24373880
D000111AcetylcysteineAcetylcysteine inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
D000111AcetylcysteineAcetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
D000111Acetylcysteine"Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of PARP1 protein]"20674558
D000111Acetylcysteine[Glucose deficiency co-treated with Acetylcysteine] results in increased cleavage of PARP1 protein17309078
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of PARP1 protein]24157283
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]21565247
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D000111AcetylcysteineAcetylcysteine inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein]22909951
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of PARP1 protein]24614525
D000111AcetylcysteineAcetylcysteine results in increased cleavage of PARP1 protein15375156
D000111AcetylcysteineAcetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]25845326
D000111AcetylcysteineAcetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]24634002
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]18703135
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]23405080
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of PARP1 protein]22714038
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Gentamicins results in increased activity of PARP1 protein]11470263
C022918acetylenedicarboxylic acid dimethyl esteracetylenedicarboxylic acid dimethyl ester results in increased cleavage of PARP1 protein21105742
C063261acetylleucyl-leucyl-norleucinalacetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D012794Sialic AcidsSialic Acids inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein]24973090
C018425acifluorfenacifluorfen results in increased expression of PARP1 protein modified form25944804
D017255AcitretinAcitretin results in increased activity of PARP1 protein18624760
D015250AclarubicinAclarubicin affects the activity of PARP1 protein20399885
D000171AcroleinAcrolein results in increased cleavage of PARP1 protein17320762
D000171Acroleinbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Acrolein results in increased cleavage of PARP1 protein]17320762
D000171AcroleinAcrolein results in increased cleavage of PARP1 protein19596284
D020106Acrylamide4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]27634458
D020106AcrylamideAcetylcysteine inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]27634458
D020106AcrylamideAcrylamide results in increased cleavage of PARP1 protein27634458
D000255Adenosine TriphosphatePARP1 mutant form inhibits the reaction [Cadmium results in decreased abundance of Adenosine Triphosphate]21767558
D000255Adenosine TriphosphateAdenosine Triphosphate results in increased expression of PARP1 protein22253048
D000255Adenosine TriphosphatePARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate]19809895
D000255Adenosine TriphosphatePARP1 protein affects the reaction [Zinc results in decreased abundance of Adenosine Triphosphate]17728843
D000255Adenosine TriphosphateAdenosine Triphosphate results in decreased activity of PARP1 protein16012769
C042151aeroplysinin Iaeroplysinin I results in increased cleavage of PARP1 protein27120392
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of PARP1 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of PARP1 protein modified form22743290
D016604Aflatoxin B1CYP2A13 protein promotes the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form]22743290
D016604Aflatoxin B1Methoxsalen inhibits the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form]22743290
D016604Aflatoxin B1Nicotine inhibits the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form]22743290
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of PARP1 mRNA19770486
C027955aflatoxin G1aflatoxin G1 results in increased expression of PARP1 protein modified form23907605
C512484AG-012986AG-012986 results in increased cleavage of PARP1 protein22095879
C046926AH 23848[6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased cleavage of and results in increased activity of PARP1 protein19407222
D000393Air PollutantsAir Pollutants results in increased cleavage of PARP1 protein28389379
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of PARP1 mRNA"23195993
C048980ajoeneajoene analog results in increased cleavage of PARP1 protein27449564
C004363alantolactonealantolactone results in increased cleavage of PARP1 protein22721982
C012708alborixinalborixin results in increased cleavage of PARP1 protein27378626
C103303alitretinoinalitretinoin results in increased cleavage of PARP1 protein16449964
D000487AllethrinAllethrin results in decreased expression of and results in increased cleavage of PARP1 protein25072698
D000496AlloxanAlloxan results in increased degradation of PARP1 protein21982801
D000496Alloxan"saccharic acid-1,4-lactone inhibits the reaction [Alloxan results in increased degradation of PARP1 protein]"21982801
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]14645110
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]24448832
C000154alpinumisoflavonealpinumisoflavone results in increased cleavage of PARP1 protein23850732
D000525Alprazolam[Caffeine co-treated with Alprazolam] results in increased activity of PARP1 protein19490937
C077990alvocidib[alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of PARP1 protein16012789
C077990alvocidib[alvocidib co-treated with Bortezomib] results in increased cleavage of PARP1 protein15039284
C077990alvocidib[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of PARP1 protein15634644
C077990alvocidib[alvocidib co-treated with gemcitabine] results in increased cleavage of PARP1 protein15770523
C077990alvocidibalvocidib promotes the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10430095
C077990alvocidibalvocidib results in increased cleavage of PARP1 protein12170773|1251778
C077990alvocidibBCL2 protein mutant form inhibits the reaction [alvocidib results in increased cleavage of PARP1 protein]12170773
C103505AM 251AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein]19509271
D000584AmilorideAmiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]15607733|1605991
D000584AmilorideOkadaic Acid inhibits the reaction [Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]16059913
C413760aminoflavoneaminoflavone results in increased cleavage of PARP1 protein24885022
D000622Aminolevulinic AcidAminolevulinic Acid analog results in increased cleavage of PARP1 protein21138480
D000622Aminolevulinic AcidFADD mutant form inhibits the reaction [Aminolevulinic Acid analog results in increased cleavage of PARP1 protein]21138480
D0151206-Aminonicotinamide6-Aminonicotinamide inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25246272
D000625Aminooxyacetic Acid[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form25321483
D019804MesalamineMesalamine results in increased cleavage of PARP1 protein12663503
D000638Amiodarone[3-methyladenine co-treated with Amiodarone] results in increased cleavage of PARP1 protein23912912
D000638Amiodarone[TNFSF10 co-treated with Amiodarone] results in increased cleavage of PARP1 protein21292685
D000641AmmoniaPARP1 protein affects the susceptibility to Ammonia15147502
C018824ammonium acetateammonium acetate results in increased expression of PARP1 protein15147502
C018824ammonium acetateCycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]15147502
C018824ammonium acetateDizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]15147502
D000643Ammonium Chloride"(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid inhibits the reaction [4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in increased cleavage of PARP1 protein]]"14535961
D000643Ammonium Chloride4-aminocrotonic acid inhibits the reaction [Ammonium Chloride results in increased cleavage of PARP1 protein]14535961
D000643Ammonium ChlorideAmmonium Chloride affects the expression of PARP1 mRNA16483693
D000643Ammonium ChlorideAmmonium Chloride results in increased cleavage of PARP1 protein14535961
C006578anetholeanethole inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]10871845
D000841Anisomycin[Colistin co-treated with Anisomycin] results in increased cleavage of PARP1 protein28842171
C037554antimony trioxideantimony trioxide results in increased cleavage of PARP1 protein16112521
C037554antimony trioxideGlutathione deficiency promotes the reaction [antimony trioxide results in increased cleavage of PARP1 protein]16112521
D000968Antimycin A[Antimycin A co-treated with Paraquat] results in increased cleavage of PARP1 protein16237197
D000968Antimycin AAntimycin A results in increased cleavage of PARP1 protein16237197
C558369antrocinantrocin results in increased cleavage of PARP1 protein21158420
D047310Apigenin[Apigenin co-treated with 3-(4-methylphenylsulfonyl)-2-propenenitrile] results in increased cleavage of PARP1 protein24148603
D047310ApigeninApigenin results in increased cleavage of PARP1 protein24148603
D047310Apigenin[polylactic acid-polyglycolic acid copolymer co-treated with Apigenin] results in increased cleavage of PARP1 protein24070738
D047310Apigenin[TNFSF10 protein results in increased susceptibility to Apigenin] which results in increased cleavage of PARP1 protein29247770
D047310ApigeninApigenin inhibits the reaction [Brefeldin A results in increased cleavage of PARP1 protein]20493918
D047310ApigeninApigenin inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
D047310ApigeninApigenin inhibits the reaction [Thapsigargin results in increased cleavage of PARP1 protein]20493918
D016718Arachidonic Acid"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased cleavage of PARP1 protein]"19540902
D016718Arachidonic AcidArachidonic Acid results in increased cleavage of PARP1 protein19540902|2113227
D016718Arachidonic AcidArachidonic Acid results in increased cleavage of PARP1 protein10403056
C000228aristolochic acid Iaristolochic acid I results in increased expression of PARP1 protein modified form26656393
C000228aristolochic acid I3-methyladenine inhibits the reaction [aristolochic acid I results in increased cleavage of PARP1 protein]23939141
C000228aristolochic acid Iaristolochic acid I results in increased cleavage of PARP1 protein23939141
C000228aristolochic acid IATG5 affects the reaction [aristolochic acid I results in increased cleavage of PARP1 protein]23939141
C061640arjunolic acidarjunolic acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21420465
D001151ArsenicArsenic results in increased cleavage of PARP1 protein19782097
D001151ArsenicArsenic results in decreased expression of PARP1 mRNA21332098
D001151ArsenicArsenic results in decreased expression of PARP1 protein21332098
D001151ArsenicArsenic results in increased cleavage of PARP1 protein26385919
D001151ArsenicCurcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 mRNA]21332098
D001151ArsenicCurcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 protein]21332098
D001151ArsenicArsenic results in increased cleavage of PARP1 protein28903487
D001151ArsenicBDNF protein inhibits the reaction [Arsenic results in increased cleavage of PARP1 protein]28903487
D001151ArsenicNOG protein inhibits the reaction [Arsenic results in increased cleavage of PARP1 protein]28903487
D001151Arsenicstaurosporine aglycone inhibits the reaction [NOG protein inhibits the reaction [Arsenic results in increased cleavage of PARP1 protein]]28903487
C058317arsenic disulfidearsenic disulfide results in increased degradation of PARP1 protein17615687
C006632arsenic trioxide17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]19371599
C006632arsenic trioxide"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]"17237268
C006632arsenic trioxide6-Aminonicotinamide inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25246272
C006632arsenic trioxideAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C006632arsenic trioxideAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]17237268
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25246272
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of PARP1 protein]25972196
C006632arsenic trioxideAcetylcysteine inhibits the reaction [[sulforafan co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]22922937
C006632arsenic trioxideAcetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]18281123
C006632arsenic trioxidearsenic trioxide affects the localization of PARP1 protein modified form15131059
C006632arsenic trioxide[arsenic trioxide co-treated with Bortezomib] results in increased degradation of PARP1 protein17495969
C006632arsenic trioxide[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein23082001
C006632arsenic trioxide[arsenic trioxide co-treated with IL24 protein] results in decreased expression of PARP112883035
C006632arsenic trioxide[arsenic trioxide co-treated with MIR15A co-treated with MIR16-1] results in increased cleavage of PARP1 protein21056550
C006632arsenic trioxide[arsenic trioxide co-treated with PD 173074] results in increased expression of PARP1 protein modified form27794399
C006632arsenic trioxide[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein17237268
C006632arsenic trioxide[arsenic trioxide co-treated with phytosphingosine] results in increased cleavage of PARP1 protein17237268
C006632arsenic trioxide[arsenic trioxide co-treated with Plant Extracts] results in increased cleavage of PARP1 protein26160715
C006632arsenic trioxidearsenic trioxide promotes the reaction [Curcumin results in increased expression of PARP1 protein modified form]27430728
C006632arsenic trioxidearsenic trioxide promotes the reaction [matrine results in increased cleavage of PARP1 protein]23700110
C006632arsenic trioxidearsenic trioxide promotes the reaction [zoledronic acid results in increased cleavage of PARP1 protein]20977926
C006632arsenic trioxidearsenic trioxide results in decreased expression of PARP1 protein19695276|2541905
C006632arsenic trioxidearsenic trioxide results in increased activity of PARP1 protein11304686
C006632arsenic trioxidearsenic trioxide results in increased cleavage of and results in increased activity of PARP1 protein19408305
C006632arsenic trioxidearsenic trioxide results in increased cleavage of PARP1 protein10382944|1047774
C006632arsenic trioxidearsenic trioxide results in increased degradation of PARP1 protein16166054
C006632arsenic trioxidearsenic trioxide results in increased expression of PARP1 protein25972196
C006632arsenic trioxidearsenic trioxide results in increased expression of PARP1 protein modified form27430728
C006632arsenic trioxide[arsenic trioxide results in increased susceptibility to PD 173074] which results in increased expression of PARP1 protein modified form27794399
C006632arsenic trioxidebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C006632arsenic trioxideCurcumin promotes the reaction [arsenic trioxide results in increased expression of PARP1 protein modified form]27430728
C006632arsenic trioxideDeoxyglucose inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25246272
C006632arsenic trioxideDithiothreitol inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]18022205
C006632arsenic trioxide[Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein21078540
C006632arsenic trioxideGSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C006632arsenic trioxideKNK 437 promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]19371599
C006632arsenic trioxidematrine promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]23700110
C006632arsenic trioxideMCL1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C006632arsenic trioxideNCF2 mutant form inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]22532027
C006632arsenic trioxide[PD 173074 results in increased susceptibility to arsenic trioxide] which results in increased expression of PARP1 protein modified form27794399
C006632arsenic trioxidePRDX3 protein affects the reaction [arsenic trioxide results in increased cleavage of and results in increased activity of PARP1 protein]19408305
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]16328441
C006632arsenic trioxidepyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]18281123
C006632arsenic trioxideSB 203580 inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]16328441
C006632arsenic trioxide[sulforafan co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein22922937
C006632arsenic trioxide[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein18281123
C006632arsenic trioxideTGIF1 mutant form promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25791921
C006632arsenic trioxideTGIF1 protein inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25791921
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of PARP1 protein]24157283
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]21565247
C006632arsenic trioxide"arsenic trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of PARP1 protein]"28587418
C006632arsenic trioxidearsenic trioxide results in increased activity of PARP1 protein24157283
C006632arsenic trioxidearsenic trioxide results in increased cleavage of PARP1 protein15761769|2156524
C006632arsenic trioxide[Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein21078540
C006632arsenic trioxideAcetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]24634002
C006632arsenic trioxidearsenic trioxide results in increased cleavage of PARP1 protein24634002
C006632arsenic trioxidearsenic trioxide results in increased expression of PARP1 protein28391263
C006632arsenic trioxidesalvianolic acid A inhibits the reaction [arsenic trioxide results in increased expression of PARP1 protein]28391263
C006632arsenic trioxide[Thiostrepton co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein18297286
C015001arseniteCAT protein inhibits the reaction [[epigallocatechin gallate co-treated with arsenite] results in increased cleavage of PARP1 protein]26375285
C015001arsenite[epigallocatechin gallate co-treated with arsenite] results in increased cleavage of PARP1 protein26375285
C015001arsenitearsenite results in decreased activity of PARP1 protein17011244|1870713
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which affects the localization of AIFM1 protein22387748
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which affects the localization of CYCS protein22387748
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which results in decreased chemical synthesis of Poly Adenosine Diphosphate Ribose22387748
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which results in decreased cleavage of and results in decreased activity of CASP3 protein22387748
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which results in decreased cleavage of and results in decreased activity of CASP7 protein22387748
C015001arsenite[arsenite results in decreased activity of PARP1 protein] which results in decreased cleavage of and results in decreased activity of CASP9 protein22387748
C015001arsenitearsenite results in decreased cleavage of PARP1 protein22387748
C015001arsenitearsenite results in increased cleavage of PARP1 protein20083129|2226086
C015001arsenitearsenite results in increased expression of PARP1 protein18392098
C015001arseniteCurcumin promotes the reaction [arsenite results in increased expression of PARP1 protein]18392098
C015001arsenitePARP1 protein affects the susceptibility to arsenite22387748
C015001arseniteTP53 mutant form inhibits the reaction [arsenite results in increased cleavage of PARP1 protein]22260869
C015001arseniteZinc inhibits the reaction [arsenite results in decreased activity of PARP1 protein]18707137
C015001arsenitearsenite results in increased degradation of PARP1 protein9766529
C039726artesunateartesunate results in increased cleavage of PARP1 protein24704559
C000606252ARV-825ARV-825 results in increased cleavage of PARP1 protein26051217
D001194AsbestosAsbestos results in increased expression of and results in decreased activity of PARP1 protein21543585
D001194AsbestosAsbestos results in increased expression of PARP1 mRNA21543585
D017639Asbestos, Amosite"3-aminobenzamide inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]"11217149
D017639Asbestos, Amosite"Asbestos, Amosite results in increased activity of PARP1 protein"11217149
D017639Asbestos, Amosite"CAT protein inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]"11217149
D017639Asbestos, Amosite"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]"11217149
D017639Asbestos, Amosite"[Smoke analog co-treated with Asbestos, Amosite] results in increased activity of PARP1 protein"11217149
D017638Asbestos, Crocidolite"3-aminobenzamide inhibits the reaction [Asbestos, Crocidolite results in increased activity of PARP1 protein]"21543585
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased cleavage of PARP1 protein"17191120|1978379
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of and results in increased activity of PARP1 protein"20616036|2154358
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of PARP1 mRNA"20616036
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D001205Ascorbic AcidAscorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]17301063
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]19433269
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of PARP1 protein]21262251
C108637aspartyl-glutamyl-valyl-aspartalaspartyl-glutamyl-valyl-aspartal inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]14976342
C010302aspidin BBaspidin BB results in increased expression of PARP1 protein modified form23628508
D001241Aspirin[Aspirin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein18483385
D001241AspirinAspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein]17644113
D001241AspirinAspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]16199534
D001241AspirinAspirin promotes the reaction [troglitazone results in increased cleavage of PARP1 protein]19908241
D001241AspirinAspirin results in increased cleavage of and results in increased activity of PARP1 protein15481331
D001241AspirinAspirin results in increased cleavage of PARP1 protein11228543|1153286
D001241AspirinBCL2 protein inhibits the reaction [Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]16199534
D001241Aspirintroglitazone promotes the reaction [Aspirin results in increased cleavage of PARP1 protein]19908241
D000069059Atorvastatin Calcium[Atorvastatin Calcium co-treated with Celecoxib] results in increased cleavage of PARP1 protein18172863
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased cleavage of PARP1 protein16470222|2087680
D000069059Atorvastatin Calciumbafilomycin A1 promotes the reaction [Atorvastatin Calcium results in increased cleavage of PARP1 protein]20876807
D000069059Atorvastatin CalciumCDKN1A protein mutant form inhibits the reaction [Atorvastatin Calcium results in increased cleavage of PARP1 protein]20876807
D000069059Atorvastatin CalciumATG5 mutant form promotes the reaction [Atorvastatin Calcium results in increased cleavage of PARP1 protein]20876807
D000069059Atorvastatin CalciumAtorvastatin Calcium results in increased cleavage of PARP1 protein20876807
C026304atranorinatranorin results in increased cleavage of PARP1 protein26969521
D001310AuranofinAuranofin results in decreased activity of PARP1 protein21370912
D001310AuranofinAuranofin results in increased cleavage of PARP1 protein15159275
C099015azaspiraneazaspirane results in increased cleavage of PARP1 protein15705788
C517975AZD 6244AZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of PARP1 protein]]27222248
C517975AZD 6244AZD 6244 results in increased cleavage of PARP1 protein17876044
C517975AZD 6244Doxorubicin promotes the reaction [AZD 6244 results in increased cleavage of PARP1 protein]17876044
D001397Azoxymethane[Camptothecin co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein25449198
D001397Azoxymethane[Plant Extracts co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein25449198
C057620bafilomycin Abafilomycin A promotes the reaction [BO-1012 results in increased cleavage of PARP1 protein]24823293
C057620bafilomycin A[lapatinib co-treated with bafilomycin A] results in increased cleavage of PARP1 protein25981168
C057620bafilomycin Abafilomycin A promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
C040929bafilomycin A1bafilomycin A1 promotes the reaction [Atorvastatin Calcium results in increased cleavage of PARP1 protein]20876807
C040929bafilomycin A1bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]28063998
C040929bafilomycin A1bafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
C040929bafilomycin A1bafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]24321340
C040929bafilomycin A1bafilomycin A1 promotes the reaction [Nickel results in increased cleavage of PARP1 protein]28330870
C040929bafilomycin A1bafilomycin A1 results in increased cleavage of PARP1 protein21616090|2598116
C040929bafilomycin A1bafilomycin A1 results in increased expression of PARP1 protein modified form28063998
C040929bafilomycin A1BNIP3 mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]25981168
C040929bafilomycin A1HIF1A mutant form promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein]25981168
C040929bafilomycin A1bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
C012765bakuchiol[TNFSF10 protein co-treated with bakuchiol] results in increased cleavage of PARP1 protein27033605
C012765bakuchiolbakuchiol results in increased cleavage of PARP1 protein17292878
C012765bakuchiolbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [bakuchiol results in increased cleavage of PARP1 protein]17292878
C012765bakuchiolpyrazolanthrone inhibits the reaction [bakuchiol results in increased cleavage of PARP1 protein]17292878
C060988baohuoside Ibaohuoside I results in increased cleavage of PARP1 protein19289254|2268763
C060988baohuoside IDinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]19289254
C060988baohuoside IPTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein]19289254
C416282BAY 11-7085BAY 11-7085 inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]25845326
C580697BDMC-ABDMC-A results in increased cleavage of PARP1 protein24365254
C487081belinostatbelinostat results in increased cleavage of PARP1 protein18223231
C487081belinostatBortezomib promotes the reaction [belinostat results in increased cleavage of PARP1 protein]18223231
D000069461Bendamustine HydrochlorideBendamustine Hydrochloride results in increased cleavage of PARP1 protein12948851
D001542BenomylBenomyl results in increased cleavage of PARP1 protein16903866
C030935benz(a)anthracenebenz(a)anthracene results in increased cleavage of PARP1 protein21132278
C037689benzamidebenzamide inhibits the reaction [PARP1 protein binds to MOR enhancer mutant form]19447888
C037689benzamidebenzamide inhibits the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]19447888
C037689benzamidebenzamide inhibits the reaction [TNF protein promotes the reaction [[PARP1 protein binds to MOR enhancer mutant form] which results in increased expression of MOR mRNA]]19447888
C037689benzamidebenzamide results in decreased activity of PARP1 protein17669606|1869594
C037689benzamide[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
C037689benzamide[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
C037689benzamidebenzamide inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
C037689benzamidebenzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
C037689benzamidebenzamide results in decreased activity of PARP1 protein11593040
C037689benzamide[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Hydrogen Peroxide11593040
C037689benzamide[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine11593040
C037689benzamidebenzamide results in decreased expression of PARP1 protein19998477
C037689benzamidebenzamide results in decreased activity of PARP1 protein12411406
C037689benzamidebenzamide results in decreased activity of PARP1 protein14769338
D001554BenzeneBenzene analog results in increased cleavage of PARP1 protein15826604
D001554BenzeneBenzene results in decreased expression of PARP1 mRNA20230882
D001554BenzeneBenzene results in increased methylation of PARP1 promoter20230882
D001554Benzenedecitabine inhibits the reaction [Benzene results in decreased expression of PARP1 mRNA]20230882
D001554Benzenedecitabine inhibits the reaction [Benzene results in increased methylation of PARP1 promoter]20230882
D001554Benzenetrichostatin A inhibits the reaction [Benzene results in decreased expression of PARP1 mRNA]20230882
D001554Benzenetrichostatin A inhibits the reaction [Benzene results in increased methylation of PARP1 promoter]20230882
C017228benzo(a)pyrene 7,8-dihydrodiol"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased cleavage of PARP1 protein]"15572374
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in increased cleavage of PARP1 protein"15572374
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased cleavage of PARP1 protein21132278
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased cleavage of PARP1 protein21132278
D001564Benzo(a)pyrene"2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein]"20840854
D001564Benzo(a)pyrene"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein]"20840854
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of PARP1 mRNA20064835
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased cleavage of PARP1 protein20840854|2468577
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of PARP1 protein24664296
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of PARP1 protein]24664296
D001564Benzo(a)pyrenePARP1 protein results in decreased susceptibility to Benzo(a)pyrene19247804
D001564Benzo(a)pyreneVitamin E inhibits the reaction [Benzo(a)pyrene results in increased expression of PARP1 protein]24664296
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [AHR protein binds to PARP1 promoter]19654925
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of PARP1 mRNA19770486
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased cleavage of PARP1 protein19041363
D003374CoumarinsCoumarins analog results in increased cleavage of PARP1 protein25231984
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased cleavage of PARP1 protein]26549707
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [IL1B protein results in increased cleavage of PARP1 protein]17404069
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]21642427
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [bakuchiol results in increased cleavage of PARP1 protein]17292878
C110772benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of PARP1 protein]15183012
C427308benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]17308071
C427308benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketonebenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
D001585Benzoyl Peroxide3-aminobenzamide inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]2120135|2126186
D001585Benzoyl PeroxideBenzoyl Peroxide results in increased activity of PARP1 protein2120135|2126186
D001585Benzoyl PeroxideButylated Hydroxytoluene inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]2126186
D001585Benzoyl PeroxideCAT protein inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]2126186
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Acrolein results in increased cleavage of PARP1 protein]17320762
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]21067863
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]21067863
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone"benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [N,N-dimethylphytosphingosine results in increased cleavage of PARP1 protein]"19481559
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [manganese chloride results in increased cleavage of PARP1 protein]21704098
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of PARP1 protein]23747687
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C403754benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased degradation of PARP1 protein]19716835
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein15498850|1605142
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein20100472
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide results in increased cleavage of PARP1 protein]26549707
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [acetylbritannilatone analog results in increased cleavage of PARP1 protein]27262408
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Bortezomib promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]]24291039
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein]25770930
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [gambogic acid promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]]24291039
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]27729209
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]26887594
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Quercetin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]20096292
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]14688022
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [silybin results in increased cleavage of PARP1 protein]24440808
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]21642427
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [gemcitabine results in increased cleavage of PARP1 protein]17146438
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]25940438
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein]25940438
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]24373880
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C517629benzyloxycarbonyl-valyl-alanyl-aspartic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
C103712benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethanebenzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]14640974
C103712benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethanebenzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Nickel results in increased cleavage of PARP1 protein]28330870
D001599Berberine[Berberine co-treated with Niacinamide] results in increased cleavage of PARP1 protein26712469
D001599BerberineBerberine results in increased cleavage of PARP1 protein16505103
C000617228beta-2-himachalen-6-olbeta-2-himachalen-6-ol results in increased cleavage of PARP1 protein28782499
C031215betadexbetadex inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
D004958Estradiol[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein21732360
D004958EstradiolEstradiol promotes the reaction [PARP1 protein binds to HTR1A promoter mutant form]21990073
D004958Estradiol[Estradiol promotes the reaction [PARP1 protein binds to HTR1A promoter mutant form]] which results in decreased expression of HTR1A mRNA21990073
D004958EstradiolEstradiol results in increased cleavage of PARP1 protein21732360
D004958Estradiol[Estradiol results in increased expression of PARP1 mRNA] which results in increased susceptibility to Cisplatin28323900
D004958Estradiol[Estradiol results in increased expression of PARP1 mRNA] which results in increased susceptibility to Doxorubicin28323900
D004958Estradiolfulvestrant inhibits the reaction [Estradiol results in increased cleavage of PARP1 protein]21732360
D004958EstradiolSB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein]21732360
D004958EstradiolEstradiol results in decreased cleavage of PARP1 protein24894866
D004958Estradiolresveratrol inhibits the reaction [Estradiol results in decreased cleavage of PARP1 protein]24894866
C002503betulinbetulin analog promotes the reaction [Oxygen deficiency results in increased expression of PARP1 protein modified form]26540049
C002070betulinic acidbetulinic acid results in increased expression of PARP1 protein modified form26540049
C516541BI D1870BI D1870 inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
C516541BI D1870BI D1870 results in increased cleavage of PARP1 protein25246272
D001663BilirubinBilirubin results in increased expression of PARP1 protein modified form27578021
D001663Bilirubin4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of PARP1 protein modified form]27578021
C004541biochanin Abiochanin A results in increased cleavage of PARP1 protein12791511
D001688Biological ProductsBiological Products results in increased cleavage of PARP1 protein28219700
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
C006780bisphenol Abisphenol A affects the expression of PARP1 mRNA21786754
C006780bisphenol Abisphenol A results in increased expression of PARP1 mRNA29027980
C006780bisphenol Abisphenol A results in decreased expression of PARP1 mRNA29275510
C006780bisphenol Abisphenol A affects the expression of PARP1 mRNA25181051
C006780bisphenol Abisphenol A results in decreased cleavage of PARP1 protein24884420
C006780bisphenol Abisphenol A results in decreased expression of PARP1 protein27189055
C006780bisphenol Abisphenol A results in increased methylation of PARP1 gene28505145
C006780bisphenol AGenistein inhibits the reaction [bisphenol A results in decreased cleavage of PARP1 protein]24884420
C518299BIX 01294[BIX 01294 results in increased susceptibility to Imatinib Mesylate] which results in increased cleavage of PARP1 protein25079219
C533207BIX 02189BIX 02189 promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]22521884
D001761BleomycinBleomycin results in increased expression of PARP1 protein16317386
D001761BleomycinBleomycin results in increased cleavage of PARP1 protein15371238
C000591165BO-10123-methyladenine promotes the reaction [BO-1012 results in increased cleavage of PARP1 protein]24823293
C000591165BO-1012ATG7 mutant form promotes the reaction [BO-1012 results in increased cleavage of PARP1 protein]24823293
C000591165BO-1012bafilomycin A promotes the reaction [BO-1012 results in increased cleavage of PARP1 protein]24823293
C000591165BO-1012BO-1012 results in increased cleavage of PARP1 protein24823293
C000591165BO-1012CHEK1 mutant form promotes the reaction [BO-1012 results in increased cleavage of PARP1 protein]24823293
C115950bornyl caffeatebornyl caffeate results in increased cleavage of PARP1 protein24907532
D000069286BortezomibAKT1 protein inhibits the reaction [[Bortezomib co-treated with sorafenib] results in increased cleavage of PARP1 protein]16985072
D000069286BortezomibAKT1 protein inhibits the reaction [[Bortezomib co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein]19261616
D000069286Bortezomib[alvocidib co-treated with Bortezomib] results in increased cleavage of PARP1 protein15039284
D000069286Bortezomib[arsenic trioxide co-treated with Bortezomib] results in increased degradation of PARP1 protein17495969
D000069286Bortezomibbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Bortezomib promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]]24291039
D000069286Bortezomibbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [gambogic acid promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]]24291039
D000069286Bortezomib[Bortezomib co-treated with abexinostat] results in increased activity of PARP1 protein19417023
D000069286Bortezomib[Bortezomib co-treated with Butyrates] results in increased degradation of PARP1 protein12893773
D000069286Bortezomib"[Bortezomib co-treated with N,N-dimethylsphingosine] results in increased cleavage of PARP1 protein"21195056
D000069286Bortezomib[Bortezomib co-treated with sorafenib] results in increased cleavage of PARP1 protein16985072
D000069286Bortezomib[Bortezomib co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein12902978|1926161
D000069286Bortezomib[Bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of PARP1 protein16904634
D000069286Bortezomib[Bortezomib co-treated with vorinostat] results in increased degradation of PARP1 protein12893773
D000069286BortezomibBortezomib promotes the reaction [belinostat results in increased cleavage of PARP1 protein]18223231
D000069286BortezomibBortezomib promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]24291039
D000069286BortezomibBortezomib promotes the reaction [romidepsin results in increased cleavage of PARP1 protein]18223231
D000069286BortezomibBortezomib promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]17510429|2046107
D000069286BortezomibBortezomib results in increased cleavage of and results in increased activity of PARP1 protein17510429
D000069286BortezomibBortezomib results in increased cleavage of PARP1 protein16617327|1765933
D000069286BortezomibBortezomib results in increased expression of PARP1 protein17156654
D000069286Bortezomib[Bortezomib results in increased susceptibility to and results in increased activity of TNFSF10 protein] which results in increased cleavage of PARP1 protein17326159
D000069286Bortezomib[BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased cleavage of PARP1 protein25522274
D000069286Bortezomib[Curcumin co-treated with Bortezomib] results in increased cleavage of PARP1 protein19372569
D000069286Bortezomib[Dichlororibofuranosylbenzimidazole co-treated with Bortezomib] results in increased cleavage of PARP1 protein15039284
D000069286Bortezomibgambogic acid promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]24291039
D000069286Bortezomib[RB1 mutant form results in increased susceptibility to Bortezomib] which results in increased cleavage of PARP1 protein25522274
D000069286BortezomibSCIO-469 promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]16617327
D000069286BortezomibTNFRSF10B mutant form inhibits the reaction [Bortezomib promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]17510429
D000069286BortezomibTNFRSF10B mutant form inhibits the reaction [Bortezomib results in increased cleavage of PARP1 protein]17510429
D000069286BortezomibTNFSF10 protein promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]17659339
D000069286BortezomibTP53BP1 protein affects the reaction [[BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased cleavage of PARP1 protein]25522274
C072116BPDE-II2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [BPDE-II results in increased cleavage of PARP1 protein]15572374
C072116BPDE-IIBPDE-II results in increased cleavage of PARP1 protein15572374
C072116BPDE-IIU 0126 inhibits the reaction [BPDE-II results in increased cleavage of PARP1 protein]15572374
C089020brassininbrassinin analog results in increased cleavage of PARP1 protein24747292
C044362brazilinbafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form]28063998
C044362brazilinBECN1 inhibits the reaction [brazilin results in increased expression of PARP1 protein modified form]28063998
C044362brazilinbrazilin results in increased expression of PARP1 protein modified form28063998
D020126Brefeldin AApigenin inhibits the reaction [Brefeldin A results in increased cleavage of PARP1 protein]20493918
D020126Brefeldin ABrefeldin A results in increased cleavage of PARP1 protein20493918
C022777bufalinbufalin results in increased cleavage of PARP1 protein23091618
C022777bufalinHSPB1 protein inhibits the reaction [bufalin results in increased cleavage of PARP1 protein]23091618
D002066BusulfanBusulfan results in increased cleavage of PARP1 protein18339423
D002066Busulfan[clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased cleavage of PARP1 protein20933509
D002066Busulfan[decitabine co-treated with Busulfan] results in increased cleavage of PARP1 protein19732952
D002066Busulfanpifithrin inhibits the reaction [[decitabine co-treated with Busulfan] results in increased cleavage of PARP1 protein]19732952
C040918buteinbutein results in increased cleavage of PARP1 protein24931875
D019328Buthionine Sulfoximine"Buthionine Sulfoximine promotes the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate affects the cleavage of PARP1 protein]"20962031
D019328Buthionine SulfoximineButhionine Sulfoximine promotes the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D002084Butylated HydroxytolueneButylated Hydroxytoluene inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein]2126186
D002084Butylated HydroxytolueneButylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2126186
D020122tert-Butylhydroperoxide"1-(3,4-dihydroxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]"29111459
D020122tert-Butylhydroperoxideacetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]29111459
D020122tert-ButylhydroperoxideAcetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]29111459
D020122tert-Butylhydroperoxide"Drugs, Chinese Herbal inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PARP1 protein]"28733231
D020122tert-ButylhydroperoxideLY96 protein affects the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]29111459
D020122tert-Butylhydroperoxidenectandrin-B inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]27511913
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of PARP1 protein28733231
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased cleavage of PARP1 protein27511913|2911145
D020122tert-ButylhydroperoxideCatechin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]16753784
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased cleavage of PARP1 protein16753784
D020122tert-ButylhydroperoxideCurcumin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]15569404
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased cleavage of PARP1 protein15569404
D002087Butyrates[Bortezomib co-treated with Butyrates] results in increased degradation of PARP1 protein12893773
D002087ButyratesButyrates results in increased cleavage of PARP1 protein17431121
D002087ButyratesButyrates results in increased degradation of PARP1 protein15177505
D020148Butyric AcidButyric Acid results in increased cleavage of PARP1 protein27830268
C488734C 1305PARP1 gene mutant form results in increased susceptibility to C 130515231658
C584509C646 compoundC646 compound results in decreased acetylation of PARP1 protein27064363
D002104CadmiumCadmium results in increased activity of and results in increased cleavage of PARP1 protein24824807
D002104CadmiumPARP1 mutant form inhibits the reaction [Cadmium results in decreased abundance of Adenosine Triphosphate]21767558
D002104CadmiumCadmium results in decreased activity of PARP1 protein16677676
D002104Cadmium"[1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid co-treated with Egtazic Acid] inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]"29111403
D002104Cadmium"1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]"29111403
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104Cadmiumacetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104CadmiumATG5 protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104Cadmiumbafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104Cadmiumbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104CadmiumCadmium results in increased cleavage of PARP1 protein29111403
D002104CadmiumCadmium results in increased expression of PARP1 mRNA26187450
D002104Cadmiumcalpeptin inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104CadmiumChloroquine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104CadmiumEgtazic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104CadmiumSirolimus promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002104Cadmium2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumAcetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumAscorbic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]19433269
D002104CadmiumATG5 protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104Cadmiumbafilomycin A promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104Cadmiumbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumCadmium results in increased activity of and results in increased cleavage of PARP1 protein24824807
D002104CadmiumCadmium results in increased cleavage of PARP1 protein19433269|2374131
D002104CadmiumChloroquine promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumGSK3A protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumGSK3B protein affects the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumLithium Chloride promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104Cadmiumrottlerin inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumSB 216763 promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D002104CadmiumCadmium results in increased cleavage of PARP1 protein16785314
D002104CadmiumGLRX protein inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]16785314
D002104Cadmiumoxalomalic acid promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]16785314
C028031cadmium acetatecadmium acetate results in increased cleavage of PARP1 protein15450950
C028031cadmium acetatecadmium acetate affects the expression of PARP1 mRNA16249259
C028031cadmium acetatecadmium acetate results in increased cleavage of PARP1 protein24577723|2504395
C028031cadmium acetatepuerarin inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]27717697
C028031cadmium acetatepyrazolanthrone inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]24577723|2504395
C028031cadmium acetateU 0126 inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]24577723|2504395
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]"21544200
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]18703135
D019256Cadmium ChlorideBIX 02189 promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]22521884
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein18703135
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of PARP1 protein21544200|2180909
D019256Cadmium ChlorideCadmium Chloride results in increased expression of and results in increased cleavage of PARP1 protein21796402
D019256Cadmium ChlorideCadmium Chloride results in increased expression of PARP1 protein modified form24291162
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D019256Cadmium ChlorideNGFR protein affects the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21796402
D019256Cadmium Chloridesalubrinal inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21809093
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of PARP1 mRNA23741332
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]"18850067
D019256Cadmium Chloridearjunolic acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21420465
D019256Cadmium ChlorideCadmium Chloride affects the cleavage of PARP1 protein18506790
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of PARP1 protein18850067|2142046
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]"21544200
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]18703135
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]23405080
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein18703135
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of PARP1 protein21544200|2340508
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D019256Cadmium Chloridepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]23405080
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D019256Cadmium ChlorideCadmium Chloride results in increased cleavage of PARP1 protein16785314
D019256Cadmium ChlorideGLRX protein inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]16785314
D019256Cadmium Chlorideoxalomalic acid promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]16785314
D019187Cadmium CompoundsCadmium Compounds results in increased cleavage of PARP1 protein23499788|2568439
C037123cadmium sulfate2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C037123cadmium sulfate4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C037123cadmium sulfateAcetylcysteine inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C037123cadmium sulfatecadmium sulfate results in increased cleavage of PARP1 protein14687664
C037123cadmium sulfatediphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C028337cadmium telluridecadmium telluride analog results in increased cleavage of PARP1 protein23485651
D002110CaffeineCaffeine affects the cleavage of PARP1 protein19242509
D002110Caffeine[Caffeine co-treated with Alprazolam] results in increased activity of PARP1 protein19490937
D002110CaffeineCaffeine promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
D002110CaffeineCaffeine results in increased cleavage of and results in increased expression of PARP1 protein16522534
D002110CaffeineCaffeine results in increased cleavage of PARP1 protein21229324
C080866cagA protein, Helicobacter pylori"cagA protein, Helicobacter pylori results in decreased cleavage of PARP1 protein"26427350
C080866cagA protein, Helicobacter pylori"ginsenoside Rg3 inhibits the reaction [cagA protein, Helicobacter pylori results in decreased cleavage of PARP1 protein]"26427350
D002118CalciumPARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium]20878536
C071482calpeptincalpeptin inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
C071482calpeptincalpeptin inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
C533734calycopterincalycopterin results in decreased susceptibility to [Hydrogen Peroxide results in increased cleavage of PARP1 protein]22081883
C533734calycopterincalycopterin results in decreased susceptibility to [Hydrogen Peroxide results in increased expression of PARP1 protein modified form]22081883
D002166Camptothecin"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]"24726431
D002166Camptothecin"6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide promotes the reaction [Camptothecin results in increased cleavage of PARP1 protein]"24726431
D002166CamptothecinCamptothecin results in increased cleavage of PARP1 protein11741290|1558564
D002166CamptothecinNicotine inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]24095863
D002166CamptothecinPARP1 protein affects the susceptibility to Camptothecin27694308
D002166CamptothecinPARP1 protein promotes the reaction [Camptothecin results in increased abundance of Poly Adenosine Diphosphate Ribose]27694308
D002166CamptothecinPARP1 results in decreased susceptibility to Camptothecin27694308
D002166CamptothecinRBL2 protein inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]15585644
D002166CamptothecinTHBS1 protein inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]16962673
D002166Camptothecin[Camptothecin co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein25449198
D002166CamptothecinCamptothecin results in increased cleavage of PARP1 protein18506790
D002166Camptothecin[veliparib results in decreased activity of PARP1 protein] which results in increased susceptibility to Camptothecin22158865
D002166CamptothecinCamptothecin results in increased cleavage of PARP1 protein25843524
D002166CamptothecinTetrachlorodibenzodioxin promotes the reaction [Camptothecin results in increased cleavage of PARP1 protein]25843524
D002193CantharidinCantharidin results in increased cleavage of PARP1 protein27113412
D002211Capsaicin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
D002211Capsaicin2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
D002211Capsaicin3-aminobenzamide inhibits the reaction [Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form]22226932
D002211Capsaicin3-aminobenzamide promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
D002211Capsaicin3-aminobenzamide promotes the reaction [Capsaicin results in increased expression of PARP1 protein]22226932
D002211CapsaicinCaffeine promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
D002211CapsaicinCapsaicin promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]22200406
D002211CapsaicinCapsaicin results in increased ADP-ribosylation of PARP1 protein modified form22226932
D002211CapsaicinCapsaicin results in increased cleavage of and results in increased activity of PARP1 protein22226932
D002211CapsaicinCapsaicin results in increased cleavage of PARP1 protein17505005|1985543
D002211CapsaicinCapsaicin results in increased expression of PARP1 protein22226932
D002211Capsaicinpifithrin promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
D002211CapsaicinCapsaicin results in increased cleavage of PARP1 protein17295509
D002220CarbamazepineCarbamazepine affects the expression of PARP1 mRNA24752500|2597931
D002251Carbon Tetrachloride[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased cleavage of PARP1 protein20097184
C062058carboxyamido-triazole2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[LM-1685 co-treated with carboxyamido-triazole] results in increased cleavage of PARP1 protein]15867384
C111238carboxycinnamic acid bishydroxamidecarboxycinnamic acid bishydroxamide results in increased cleavage of PARP1 protein15897598
C514968carboxymethyl-chitosancarboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased cleavage of PARP1 protein]26612707
D002330CarmustineCarmustine results in increased cleavage of PARP1 protein24193513
D002330CarmustineDisulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]24193513
D002392CatechinCatechin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]16753784
D002392CatechinCatechin results in increased expression of PARP1 protein16753784
C099555CD 437CD 437 results in increased cleavage of PARP1 protein10374879
D000068579Celecoxib[Atorvastatin Calcium co-treated with Celecoxib] results in increased cleavage of PARP1 protein18172863
D000068579CelecoxibCelecoxib analog affects the cleavage of PARP1 protein18485224
D000068579CelecoxibCelecoxib inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]17461495
D000068579CelecoxibCelecoxib promotes the reaction [docetaxel results in increased cleavage of and results in increased expression of PARP1 protein]15688368
D000068579CelecoxibCelecoxib promotes the reaction [tetracycline CMT-3 results in increased cleavage of and results in increased expression of PARP1 protein]15688368
D000068579CelecoxibCelecoxib results in increased activity of PARP1 protein12824303
D000068579CelecoxibCelecoxib results in increased cleavage of and results in increased expression of PARP1 protein15688368
D000068579CelecoxibCelecoxib results in increased cleavage of PARP1 protein15572759|1591109
D000068579Celecoxibdocetaxel promotes the reaction [Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein]15688368
D000068579CelecoxibFADD mutant form inhibits the reaction [Celecoxib results in increased cleavage of PARP1 protein]15572759
D000068579Celecoxibtetracycline CMT-3 promotes the reaction [Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein]15688368
D000068579CelecoxibTNFRSF10B mutant form inhibits the reaction [Celecoxib results in increased cleavage of PARP1 protein]15572759
D000068579CelecoxibTNFSF10 protein promotes the reaction [Celecoxib results in increased cleavage of PARP1 protein]15572759
D000068579CelecoxibCelecoxib promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein]16230411
D000068579CelecoxibCelecoxib results in decreased activity of PARP1 protein19706164
D000068579CelecoxibCelecoxib results in increased cleavage of PARP1 protein17717820
C532683CellfoodCellfood results in increased cleavage of PARP1 protein24598211
D002599ChalconeChalcone results in increased cleavage of PARP1 protein20620131
D002599ChalconeMYC protein affects the susceptibility to [Chalcone results in increased cleavage of PARP1 protein]20620131
C095591chan suchan su results in increased degradation of PARP1 protein16012733
D002635Chenodeoxycholic Acid[Chenodeoxycholic Acid co-treated with tauroursodeoxycholic acid] results in increased cleavage of PARP1 protein14976352
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased cleavage of PARP1 protein14976352
D002701ChloramphenicolCDKN1A mutant form inhibits the reaction [Chloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein]]15905168
D002701ChloramphenicolChloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein]15905168
C006972chloroacetic acidchloroacetic acid results in increased cleavage of PARP1 protein23103613
D017338Cladribine[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein15582267
D017338Cladribine[Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein15582267
D017338CladribineCladribine results in increased cleavage of PARP1 protein15582267|2167946
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of PARP1 mRNA25113976
D002738ChloroquineChloroquine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D002738ChloroquineChloroquine promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D004390ChlorpyrifosChlorpyrifos results in increased cleavage of PARP1 protein24793810
D004390ChlorpyrifosChlorpyrifos results in increased expression of PARP1 protein modified form23416140
D004390ChlorpyrifosAcetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of PARP1 protein]22714038
D004390ChlorpyrifosChlorpyrifos results in increased cleavage of PARP1 protein22714038
C529269cholix toxin, Vibrio cholerae"Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
C529269cholix toxin, Vibrio cholerae"[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein"28087840
C529269cholix toxin, Vibrio cholerae"Go 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
C529269cholix toxin, Vibrio cholerae"pyrazolanthrone inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
C529269cholix toxin, Vibrio cholerae"Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
C529269cholix toxin, Vibrio cholerae"Tetradecanoylphorbol Acetate promotes the reaction [cholix toxin, Vibrio cholerae results in increased cleavage of PARP1 protein]"28087840
C529269cholix toxin, Vibrio cholerae"U 0126 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
D002857ChromiumChromium results in increased cleavage of PARP1 protein12423593
D002858Chromium Alloys[Chromium Alloys co-treated with cobaltous chloride] results in increased cleavage of PARP1 protein25281833
D002858Chromium AlloysChromium Alloys results in increased cleavage of PARP1 protein25281833
D017608Chromium CompoundsChromium Compounds results in increased activity of PARP1 protein19406221
C074702chromium hexavalent ionAscorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]17301063
C074702chromium hexavalent ionchromium hexavalent ion results in increased cleavage of PARP1 protein15831465|1596657
C074702chromium hexavalent ionMLH1 protein affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]15831465
C074702chromium hexavalent ion"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]"15966574
C074702chromium hexavalent ionZinc affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]15966574
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of PARP1 mRNA28472532
C043561chrysinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein]25770930
C043561chrysinchrysin results in increased cleavage of PARP1 protein18455702|2577093
C043561chrysin[Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein25770930
C012842Cibacron Blue F 3GACibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]22253048
C000598873CIGB-552 peptideCIGB-552 peptide results in increased cleavage of PARP1 protein23401744
C039671ciglitazonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]21067863
C039671ciglitazonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]21067863
C039671ciglitazoneciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]21067863
C039671ciglitazoneciglitazone results in increased cleavage of and results in increased activity of PARP1 protein15492468
C039671ciglitazoneciglitazone results in increased cleavage of PARP1 protein21067863
C039671ciglitazoneDDIT3 mutant form inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]21067863
C039671ciglitazoneDDIT3 mutant form inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]21067863
C039671ciglitazoneNiflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]21067863
C012843cinnamic aldehydecinnamic aldehyde analog results in increased cleavage of PARP1 protein16343908
C002471cinobufagincinobufagin results in increased expression of PARP1 protein modified form23164673
C002471cinobufaginGSK3B protein mutant form inhibits the reaction [cinobufagin results in increased expression of PARP1 protein modified form]23164673
C002471cinobufaginSB 216763 promotes the reaction [cinobufagin results in increased expression of PARP1 protein modified form]23164673
D002939CiprofloxacinCiprofloxacin results in increased cleavage of PARP1 protein10741713
D015283CitalopramCitalopram results in increased cleavage of PARP1 protein10487422
C068329clofarabine[clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased cleavage of PARP1 protein20933509
C068329clofarabineMCL1 mutant form promotes the reaction [[resveratrol co-treated with clofarabine] results in increased cleavage of PARP1 protein]24924397
C068329clofarabine[resveratrol co-treated with clofarabine] results in increased cleavage of PARP1 protein24924397
C068329clofarabine[resveratrol co-treated with clofarabine] results in increased expression of PARP1 protein modified form24239893
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PARP1 mRNA17602206
D002997ClomipramineClomipramine results in increased cleavage of PARP1 protein10487422
D060729Coal AshCoal Ash results in increased expression of PARP1 protein modified form26773838
D060729Coal AshSimvastatin inhibits the reaction [Coal Ash results in increased expression of PARP1 protein modified form]26773838
D003035CobaltPARP1 protein modified form binds to Cobalt25549802
D003035CobaltCobalt results in increased cleavage of PARP1 protein12423593
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein]21362092
C007095cobaltiprotoporphyrincobaltiprotoporphyrin inhibits the reaction [FASLG protein results in increased cleavage of PARP1 protein]16051694
C007095cobaltiprotoporphyrincobaltiprotoporphyrin results in decreased expression of PARP1 protein modified form24736402
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased activity of CASP3 protein]] which results in decreased cleavage of PARP1 protein18819247
C007095cobaltiprotoporphyrin[cobaltiprotoporphyrin inhibits the reaction [TNF protein results in increased activity of CASP7 protein]] which results in decreased cleavage of PARP1 protein18819247
C018021cobaltous chlorideAcetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]]22172632
C018021cobaltous chlorideAcetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]22172632
C018021cobaltous chlorideAcetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]]22172632
C018021cobaltous chloride[Chromium Alloys co-treated with cobaltous chloride] results in increased cleavage of PARP1 protein25281833
C018021cobaltous chloridecobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [[PARP1 protein binds to TNFRSF10B promoter] which results in increased expression of TNFRSF10B mRNA]]19714248
C018021cobaltous chloridecobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]19714248
C018021cobaltous chloridecobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]22172632
C018021cobaltous chloridecobaltous chloride results in decreased expression of PARP1 mRNA19320972
C018021cobaltous chloridecobaltous chloride results in increased activity of PARP1 protein25125499
C018021cobaltous chloridecobaltous chloride results in increased cleavage of PARP1 protein21882223|2217263
C018021cobaltous chloridelysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in increased activity of PARP1 protein]25125499
C018021cobaltous chloridenickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]22172632
C018021cobaltous chloridezinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]19714248
D003042CocaineCocaine affects the expression of PARP1 mRNA15681117
D003042CocaineCocaine results in increased cleavage of PARP1 protein17084983
D009243NAD"[2,5,2',5'-tetrachlorobiphenyl results in increased activity of PARP1 protein] which results in decreased abundance of NAD"19433264
D009243NAD"[3,4,3',4'-tetrachlorobiphenyl results in increased activity of PARP1 protein] which results in decreased abundance of NAD"19433264
D009243NAD[3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
D009243NAD[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
D009243NAD[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
D009243NADERCC6 inhibits the reaction [NAD results in increased activity of PARP1 protein]25440059
D009243NADHydrogen Peroxide affects the reaction [PARP1 protein mutant form affects the abundance of NAD]27694308
D009243NAD[PARP1 protein co-treated with NAD] results in increased ADP-ribosylation of NR1H3 protein27026705
D009243NADPARP1 protein mutant form affects the abundance of NAD27694308
D009243NADPARP1 protein promotes the reaction [Hydrogen Peroxide results in decreased abundance of NAD]27694308
D009243NADveliparib inhibits the reaction [Hydrogen Peroxide affects the reaction [PARP1 protein mutant form affects the abundance of NAD]]27694308
D009243NADveliparib inhibits the reaction [PARP1 protein mutant form affects the abundance of NAD]27694308
D009243NADbenzamide inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D009243NADbenzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D009243NAD[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD11593040
D009243NADHydrolyzable Tannins inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D009243NADHydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D009243NAD[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD11593040
D009243NADPARP1 protein affects the abundance of NAD15147502
D009243NADNAD results in increased activity of and results in increased ADP-ribosylation of PARP1 protein25440059
D009243NAD"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [NAD results in increased activity of PARP1 protein]"25440059
D009243NADPARP1 protein affects the metabolism of and results in increased cleavage of NAD16026317
D009249NADP[3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D009249NADP[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D009249NADP[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D005576Colforsin[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]9454737
D003091Colistin[Colistin co-treated with Anisomycin] results in increased cleavage of PARP1 protein28842171
C036978concanamycin A[lapatinib co-treated with concanamycin A] results in increased cleavage of PARP1 protein25981168
C004692coomassie Brilliant Bluecoomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]22253048
D003300Copper[Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein23033007
D003300Copper[Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein17079463|2469073
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of PARP1 mRNA20971185
D003300Copper[NSC 689534 binds to Copper] which results in increased cleavage of PARP1 protein20971185
D003300Copper[Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein24690739
D019327Copper SulfateCopper Sulfate results in decreased expression of PARP1 mRNA19549813
C058120cordycepinacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C058120cordycepinADORA2A mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C058120cordycepincordycepin results in increased cleavage of PARP1 protein24704558
C058120cordycepinpifithrin inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C058120cordycepinTP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C058120cordycepinZM 241385 inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C030123coumarincoumarin results in decreased activity of PARP1 protein17669606
C030123coumarin[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
C030123coumarin[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PARP1 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of PARP1 mRNA19167446
C408982CPG-oligonucleotideCPG-oligonucleotide results in decreased expression of PARP1 mRNA21878529
C408982CPG-oligonucleotideCPG-oligonucleotide results in decreased expression of PARP1 mRNA21878529
C494620CPS 11CPS 11 results in increased cleavage of PARP1 protein15858615
C494622CPS 49CPS 49 results in increased cleavage of PARP1 protein15858615
C037886cryptotanshinonecryptotanshinone results in increased cleavage of PARP1 protein26564229
C102326cucurbitacin Eacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]27106530
C102326cucurbitacin EAcetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]27106530
C102326cucurbitacin Ecucurbitacin E results in increased cleavage of PARP1 protein27106530
C102326cucurbitacin Ecucurbitacin E results in increased cleavage of PARP1 protein27363783
C038106cucurbitacin Icucurbitacin I results in increased cleavage of PARP1 protein24858077
C029892cupric chloride[Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein19789329
C029892cupric chloride[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein21035945
C029892cupric chloridecupric chloride results in increased expression of PARP1 protein23313662
D003474Curcuminarsenic trioxide promotes the reaction [Curcumin results in increased expression of PARP1 protein modified form]27430728
D003474CurcuminCurcumin analog results in decreased expression of PARP1 mRNA26409325
D003474Curcumin[Curcumin co-treated with Bortezomib] results in increased cleavage of PARP1 protein19372569
D003474Curcumin[Curcumin co-treated with Thalidomide] results in increased cleavage of PARP1 protein19372569
D003474CurcuminCurcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 mRNA]21332098
D003474CurcuminCurcumin inhibits the reaction [Arsenic results in decreased expression of PARP1 protein]21332098
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of PARP1 protein]24664296
D003474CurcuminCurcumin inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]14724571
D003474CurcuminCurcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]23710286
D003474CurcuminCurcumin promotes the reaction [arsenic trioxide results in increased expression of PARP1 protein modified form]27430728
D003474CurcuminCurcumin promotes the reaction [arsenite results in increased expression of PARP1 protein]18392098
D003474CurcuminCurcumin results in increased cleavage of and results in increased activity of PARP1 protein16173963
D003474CurcuminCurcumin results in increased cleavage of PARP1 protein14555224|1602308
D003474CurcuminCurcumin results in increased degradation of PARP121595920
D003474CurcuminCurcumin results in increased expression of PARP1 protein modified form27430728
D003474CurcuminCurcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
D003474CurcuminCurcumin results in increased cleavage of PARP1 protein21594647
D003474Curcumin[Doxorubicin co-treated with Curcumin] results in increased cleavage of PARP1 protein18006147
D003474Curcumincarboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased cleavage of PARP1 protein]26612707
D003474CurcuminCurcumin inhibits the reaction [AGT protein modified form results in increased cleavage of PARP1 protein]26612707
D003474CurcuminCurcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]25541178
D003474CurcuminCurcumin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]15569404
D003474CurcuminCurcumin results in decreased cleavage of PARP1 protein26612707
C057862cyanoginosin LRcyanoginosin LR results in increased cleavage of PARP1 protein21684301
C057862cyanoginosin LRsulforafan inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein]21684301
D003513Cycloheximide[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein12925536
D003513Cycloheximide[Cycloheximide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein18222423
D003513CycloheximideCycloheximide results in increased cleavage of PARP1 protein16051428
D003513CycloheximideITPK1 inhibits the reaction [[Cycloheximide co-treated with TNF] results in increased cleavage of PARP1 protein]12925536
D003513CycloheximideITPK1 mutant form promotes the reaction [[Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein]12925536
D003513CycloheximideCycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]15147502
D003520Cyclophosphamide[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein15582267
D003520Cyclophosphamide[Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein15582267
D003520CyclophosphamideCyclophosphamide results in increased cleavage of PARP1 protein17898787
D003520CyclophosphamideCyclophosphamide results in decreased expression of PARP1 mRNA11906922
D003520CyclophosphamideCyclophosphamide results in increased cleavage of PARP1 protein11723234
D003520CyclophosphamideCyclophosphamide results in increased expression of PARP1 mRNA11599041
D003523CycloserineCycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
D016572CyclosporineCyclosporine results in decreased expression of PARP1 mRNA25562108
D016572CyclosporineCyclosporine results in increased cleavage of PARP1 protein22155090
D016572Cyclosporinesalubrinal inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
D016572Cyclosporine"2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]"22155090
D016572Cyclosporine"3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]"22155090
D016572CyclosporineApigenin inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
D016572Cyclosporinebisindolylmaleimide I inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
D016572CyclosporineCyclosporine results in increased cleavage of PARP1 protein22155090
D016572CyclosporineN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
D016572Cyclosporinewortmannin inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
D016572CyclosporineCyclosporine inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
C017160cypermethrincypermethrin inhibits the reaction [Docosahexaenoic Acids results in increased degradation of PARP1 protein]11341974
C017160cypermethrincypermethrin results in decreased expression of PARP1 mRNA27704156
D003561CytarabineBCL2L1 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]8840993
D003561CytarabineBCL2 protein inhibits the reaction [Cytarabine results in increased degradation of PARP1 protein]8840993
D003561Cytarabine[Cytarabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein12780785
D003561CytarabineCytarabine results in increased degradation of PARP1 protein8840993
D003566Cytidine Diphosphate CholineCytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form12443983
D003609Dactinomycin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]14640974
D003609Dactinomycinbenzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]14640974
D003609DactinomycinDactinomycin results in increased cleavage of PARP1 protein14640974
D003609DactinomycinDactinomycin promotes the reaction [TNF results in increased cleavage of PARP1 protein]16492401
D003609DactinomycinPLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]14640974
D003609Dactinomycin[TNF co-treated with Dactinomycin] results in increased cleavage of PARP1 protein16492401
D003609DactinomycinPLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]14640974
C531198dactolisibdactolisib results in increased cleavage of PARP1 protein21464613
C004742daidzeindaidzein results in increased cleavage of PARP1 protein12791511
C515055darinaparsindarinaparsin results in increased cleavage of PARP1 protein25316819
D003630DaunorubicinDaunorubicin affects the expression of PARP1 mRNA27780733
D003630Daunorubicin[Daunorubicin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein12780785
D003630DaunorubicinDaunorubicin results in increased cleavage of PARP1 protein10766178|1108253
D003630DaunorubicinDaunorubicin results in increased cleavage of PARP1 protein22252735
C017180decamethrindecamethrin results in increased activity of PARP1 protein22889898|2307663
C017180decamethrinlycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein]23076637
C014347decitabine[decitabine co-treated with Busulfan] results in increased cleavage of PARP1 protein19732952
C014347decitabine[decitabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein18636160
C014347decitabinedecitabine inhibits the reaction [Benzene results in decreased expression of PARP1 mRNA]20230882
C014347decitabinedecitabine inhibits the reaction [Benzene results in increased methylation of PARP1 promoter]20230882
C014347decitabinedecitabine inhibits the reaction [Silicon Dioxide results in decreased expression of PARP1 mRNA]20123007
C014347decitabinedecitabine results in decreased methylation of PARP1 gene20123007
C014347decitabinedecitabine results in increased cleavage of PARP1 protein23300844
C014347decitabinepifithrin inhibits the reaction [[decitabine co-treated with Busulfan] results in increased cleavage of PARP1 protein]19732952
C101278decursindecursin results in increased cleavage of PARP1 protein17723170
D003676DeferoxamineDeferoxamine results in increased cleavage of PARP1 protein21882223
D003676DeferoxamineIndomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]21882223
D003676DeferoxamineSulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]21882223
C107676deguelindeguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]17015749
C107676deguelindeguelin metabolite results in increased expression of PARP1 protein modified form19139008
C107676deguelindeguelin results in increased cleavage of PARP1 protein17035597|2298652
C107676deguelindeguelin results in increased expression of PARP1 protein modified form19139008
C107676deguelin[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein25242579
D015230Prostaglandin D2Prostaglandin D2 results in increased cleavage of PARP1 protein15843042
D015230Prostaglandin D2Prostaglandin D2 results in increased cleavage of PARP1 protein23973622
C464444dehydroxymethylepoxyquinomicindehydroxymethylepoxyquinomicin results in increased cleavage of PARP1 protein15501958
C464444dehydroxymethylepoxyquinomicinpyrazolanthrone inhibits the reaction [dehydroxymethylepoxyquinomicin results in increased cleavage of PARP1 protein]15501958
C017185delphinidindelphinidin results in decreased activity of PARP1 protein17884996
C499810delta(12)-prostaglandin J(2)"[delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12,14)-prostaglandin J2] results in increased cleavage of PARP1 protein"23973622
D013759DronabinolDronabinol results in decreased expression of PARP1 protein16818634
D013759DronabinolDronabinol results in increased cleavage of PARP1 protein17583570|1950927
D015255IdarubicinDexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 mRNA]28973540
D015255IdarubicinDexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 protein]28973540
D015255IdarubicinIdarubicin results in increased expression of PARP1 mRNA28973540
D015255IdarubicinIdarubicin results in increased expression of PARP1 protein28973540
C100698demethoxyfumitremorgin Cdemethoxyfumitremorgin C results in increased cleavage of PARP1 protein28359723
D003840Deoxycholic AcidAspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein]17644113
D003840Deoxycholic Acidcobaltiprotoporphyrin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein]21362092
D003840Deoxycholic AcidDeoxycholic Acid results in increased cleavage of PARP1 protein17644113|2136209
D003847DeoxyglucoseDeoxyglucose inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]25246272
D003847DeoxyglucoseDeoxyglucose inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
D003847DeoxyglucoseDeoxyglucose results in increased cleavage of PARP1 protein25246272
C007262deoxynivalenoldeoxynivalenol results in increased cleavage of PARP1 protein19410639
C040424destruxin Bdestruxin B results in increased cleavage of PARP1 protein22465936
D003907DexamethasoneDexamethasone inhibits the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]16144937
D003907Dexamethasone"Dexamethasone promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein]"23318440
D003907DexamethasoneDexamethasone results in increased cleavage of PARP1 protein25447644
D003907DexamethasoneDexamethasone results in increased cleavage of PARP1 protein16644695
D003907Dexamethasone[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of PARP1 protein2523799
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone results in increased cleavage of PARP1 protein]16644695
C004180dexamethasone 21-phosphatedexamethasone 21-phosphate results in increased cleavage of PARP1 protein25447644
D064730DexrazoxaneDexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 mRNA]28973540
D064730DexrazoxaneDexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 protein]28973540
D016264Dextran Sulfate[Camptothecin co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein25449198
D016264Dextran SulfateDextran Sulfate results in increased cleavage of PARP1 protein21989142
D016264Dextran Sulfate[Plant Extracts co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein25449198
D016264Dextran SulfatePlant Extracts inhibits the reaction [Dextran Sulfate results in increased cleavage of PARP1 protein]21989142
C539263di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone"di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of PARP1 protein modified form"24532803
C539263di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone"NDRG1 protein promotes the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of PARP1 protein modified form]"24532803
C042577diallyl trisulfideAcetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]22578287
C042577diallyl trisulfidediallyl trisulfide results in increased cleavage of PARP1 protein20055834|2257828
D016190CarboplatinCarboplatin results in increased cleavage of PARP1 protein15996812
D003992DibucaineDibucaine inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
C020735dibutyldichlorotindibutyldichlorotin results in increased cleavage of PARP1 protein16181675
C048074dibutyl maleatedibutyl maleate results in increased cleavage of PARP1 protein21105742
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of PARP1 mRNA21266533
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of PARP1 mRNA21266533
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of and results in increased cleavage of PARP1 protein25630799
D002945Cisplatin[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FAM168A results in decreased susceptibility to Cisplatin]] which results in increased cleavage of PARP1 protein23251525
D002945Cisplatin[3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [FAM168A results in decreased susceptibility to Cisplatin]] which results in increased cleavage of PARP1 protein23251525
D002945Cisplatin[3-aminobenzamide results in decreased activity of PARP1 protein] which results in increased susceptibility to Cisplatin21399878
D002945CisplatinAcetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]15496615
D002945CisplatinAcetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]25940438
D002945CisplatinAKT1 protein inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]21266360
D002945CisplatinBCL2 inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]21618512
D002945Cisplatinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein]25770930
D002945Cisplatinbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]25940438
D002945Cisplatin[BIN1 protein results in decreased activity of PARP1 protein] which results in increased susceptibility to Cisplatin21447800
D002945CisplatinCD40LG protein inhibits the reaction [Cisplatin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]16545138
D002945Cisplatin[Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein25770930
D002945CisplatinCisplatin inhibits the reaction [Zinc binds to PARP1 protein]21370912
D002945CisplatinCisplatin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]16545138
D002945CisplatinCisplatin promotes the reaction [Platinum binds to PARP1 protein]21370912
D002945CisplatinCisplatin results in decreased activity of PARP1 protein21370912
D002945Cisplatin[Cisplatin results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein18176112
D002945CisplatinCisplatin results in increased cleavage of PARP1 protein15496615|1600948
D002945CisplatinCisplatin results in increased expression of PARP1 protein21274007
D002945CisplatinCITED2 mutant form promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]21660965
D002945Cisplatin[CITED2 results in decreased susceptibility to Cisplatin] which results in decreased cleavage of PARP1 protein21660965
D002945CisplatinDICER1 mutant form inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]25940438
D002945Cisplatin[Estradiol results in increased expression of PARP1 mRNA] which results in increased susceptibility to Cisplatin28323900
D002945CisplatinHSPA5 protein affects the reaction [Cisplatin results in increased cleavage of PARP1 protein]27234046
D002945CisplatinIER5 protein promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]27186303
D002945CisplatinPARP1 protein results in decreased susceptibility to Cisplatin21447800
D002945Cisplatin[Proadifen co-treated with Cisplatin] results in increased cleavage of PARP1 protein26721606
D002945CisplatinQuercetin promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]25611565
D002945CisplatinS100A11 mutant form promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]25940438
D002945Cisplatin[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein25940438
D002945CisplatinSND1 mutant form promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]25940438
D002945Cisplatin[SND1 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein25940438
D002945Cisplatintauroursodeoxycholic acid inhibits the reaction [Quercetin promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]]25611565
D002945CisplatinCisplatin results in increased cleavage of PARP1 protein23628706|2456077
D002945CisplatinCisplatin results in increased expression of PARP1 protein26723870
D002945Cisplatinerdosteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]26193055
D002945CisplatinNQO1 gene mutant form inhibits the reaction [Cisplatin results in increased expression of PARP1 protein]26723870
D002945CisplatinSB 216763 inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]24560772
D002945CisplatinCisplatin results in increased cleavage of PARP1 protein23628706|2497308
D002945CisplatinCTNNA1 gene affects the reaction [Cisplatin results in increased cleavage of PARP1 protein]24973089
D002945Cisplatin[CTNNA1 protein affects the susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein27989596
D002945CisplatinFSCN2 protein inhibits the reaction [[CTNNA1 protein affects the susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]27989596
D002945CisplatinHNF1B protein inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]28119452
D002945CisplatinPARP1 results in decreased susceptibility to Cisplatin21884784
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased activity of PARP1 protein19545618
D004004Dichlororibofuranosylbenzimidazole[Dichlororibofuranosylbenzimidazole co-treated with Bortezomib] results in increased cleavage of PARP1 protein15039284
D004006DichlorvosDichlorvos results in increased activity of PARP1 protein24231740
D004006DichlorvosDichlorvos results in increased cleavage of PARP1 protein24231740
D004006Dichlorvos"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in increased activity of PARP1 protein]"24231740
D004008DiclofenacDiclofenac affects the expression of PARP1 mRNA24752500
C121718dicyclanildicyclanil results in decreased expression of PARP1 mRNA15664270
C499970dideoxypetrosynol Adideoxypetrosynol A results in increased cleavage of PARP1 protein15547680
D004026Dieldrinbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of PARP1 protein]15183012
D004026DieldrinDieldrin results in increased cleavage of PARP1 protein15183012
D004041Dietary FatsDietary Fats results in increased expression of and results in increased cleavage of PARP1 protein27551045
D004041Dietary FatsMetformin inhibits the reaction [Dietary Fats results in increased expression of and results in increased cleavage of PARP1 protein]27551045
C035088diethyl fumaratediethyl fumarate results in increased cleavage of PARP1 protein21105742
C014476diethyl maleatediethyl maleate results in increased cleavage of PARP1 protein21105742
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PARP1 mRNA17602206
D017323Dihematoporphyrin EtherCelecoxib promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein]16230411
D017323Dihematoporphyrin EtherDihematoporphyrin Ether results in increased cleavage of PARP1 protein16230411
D017323Dihematoporphyrin EtherN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein]16230411
C472036dihydromyricetinAcetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
C472036dihydromyricetinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
C472036dihydromyricetindihydromyricetin results in increased cleavage of PARP1 protein27539140
C472036dihydromyricetinpyrazolanthrone promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
C472036dihydromyricetinU 0126 promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
D0178784,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]"28343033
C472511dimethylarsinous aciddimethylarsinous acid inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]17011244
C472511dimethylarsinous aciddimethylarsinous acid results in decreased activity of PARP1 protein17011244
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased cleavage of PARP1 protein"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased cleavage of PARP1 protein]"21294050
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene promotes the reaction [A gene mutant form results in increased expression of PARP1 mRNA]"25448685
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene promotes the reaction [A gene mutant form results in increased expression of PARP1 protein]"25448685
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of PARP1 mRNA"25448685
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of PARP1 protein"25448685
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of PARP1 mRNA"23969067
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of PARP1 protein"23969067
D004126Dimethylformamide[Dimethylformamide co-treated with Carbon Tetrachloride] results in increased cleavage of PARP1 protein20097184
C004780dimethyl maleatedimethyl maleate results in increased cleavage of PARP1 protein21105742
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in increased cleavage of PARP1 protein22535522
C019357dioscindioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein]24146112
C019357dioscindioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein]24146112
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]14687664
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
D004178DiquatDiquat results in increased cleavage of PARP1 protein25693864
D004221Disulfiram[Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein23033007
D004221Disulfiram[Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein17079463|2469073
D004221Disulfiram[Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein19789329
D004221DisulfiramDisulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]24193513
D004221DisulfiramDisulfiram results in increased cleavage of PARP1 protein17079463|2419351
D004221Disulfiram[Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein24690739
D004229DithiothreitolDithiothreitol inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]18022205
D004229DithiothreitolDithiothreitol inhibits the reaction [withaferin A results in increased cleavage of PARP1 protein]20438634
D004229DithiothreitolDithiothreitol inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C009873divinyl sulfone3-methyladenine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein]24875536
C009873divinyl sulfoneAcetylcysteine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein]24875536
C009873divinyl sulfonedivinyl sulfone analog results in increased cleavage of PARP1 protein24875536
D016291Dizocilpine MaleateDizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein]15147502
C558638DLBS 1425DLBS 1425 results in increased cleavage of PARP1 protein20703095
C521792DMU-212DMU-212 results in increased cleavage of PARP1 protein24055891
C067311docetaxel2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]14724571
C067311docetaxelbenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]17308071
C067311docetaxelCelecoxib promotes the reaction [docetaxel results in increased cleavage of and results in increased expression of PARP1 protein]15688368
C067311docetaxelCurcumin inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]14724571
C067311docetaxeldocetaxel promotes the reaction [Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein]15688368
C067311docetaxeldocetaxel promotes the reaction [TNFSF10 results in increased cleavage of PARP1 protein]18404675
C067311docetaxeldocetaxel results in increased cleavage of and results in increased expression of PARP1 protein15688368
C067311docetaxeldocetaxel results in increased cleavage of PARP1 protein14724571|1597051
C067311docetaxelpyrazolanthrone inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]14724571
D004281Docosahexaenoic Acidscypermethrin inhibits the reaction [Docosahexaenoic Acids results in increased degradation of PARP1 protein]11341974
D004281Docosahexaenoic AcidsDocosahexaenoic Acids analog results in increased cleavage of PARP1 protein27041074
D004281Docosahexaenoic AcidsDocosahexaenoic Acids results in increased degradation of PARP1 protein11341974
D004281Docosahexaenoic Acidstautomycin inhibits the reaction [Docosahexaenoic Acids results in increased degradation of PARP1 protein]11341974
D004298DopamineDopamine promotes the reaction [Zinc deficiency results in increased cleavage of PARP1 protein]23377617
D004298DopamineDopamine results in increased cleavage of PARP1 protein15198987|1760329
D004298DopaminePRKN protein inhibits the reaction [Dopamine results in increased cleavage of PARP1 protein]15198987
D004298Dopamineresveratrol inhibits the reaction [Dopamine results in increased cleavage of PARP1 protein]17603292
D004298DopamineZinc deficiency promotes the reaction [Dopamine results in increased cleavage of PARP1 protein]23377617
D004317Doxorubicin"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]"20826841
D004317Doxorubicin"4-amino-1,8-naphthalimide inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein]"15456408
D004317Doxorubicin7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17285121
D004317Doxorubicin[ABCB1 protein results in decreased susceptibility to Doxorubicin] inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]20438634
D004317DoxorubicinAcetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]25824409
D004317DoxorubicinAKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinAKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinCD40LG protein inhibits the reaction [Doxorubicin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]16545138
D004317Doxorubicincobaltous chloride inhibits the reaction [Doxorubicin promotes the reaction [[PARP1 protein binds to TNFRSF10B promoter] which results in increased expression of TNFRSF10B mRNA]]19714248
D004317Doxorubicincobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]19714248
D004317DoxorubicinDoxorubicin affects the cleavage of PARP1 protein15870702
D004317DoxorubicinDoxorubicin affects the expression of PARP1 mRNA27780733
D004317DoxorubicinDoxorubicin analog results in increased cleavage of PARP1 protein15981920
D004317Doxorubicin[Doxorubicin binds to TF protein] which results in increased activity of PARP1 protein24998637
D004317Doxorubicin[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein17339365
D004317Doxorubicin[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein17339365
D004317DoxorubicinDoxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]26047893
D004317Doxorubicin"Doxorubicin promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein]"20826841
D004317DoxorubicinDoxorubicin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]16545138
D004317DoxorubicinDoxorubicin promotes the reaction [PARP1 protein binds to TNFRSF10B promoter]19714248
D004317DoxorubicinDoxorubicin results in increased activity of PARP1 protein15456408
D004317DoxorubicinDoxorubicin results in increased cleavage of PARP1 protein10766178|1555562
D004317DoxorubicinDoxorubicin results in increased degradation of PARP1 protein17418594
D004317DoxorubicinDPP4 protein promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]15753397
D004317Doxorubicin[Estradiol results in increased expression of PARP1 mRNA] which results in increased susceptibility to Doxorubicin28323900
D004317DoxorubicinFASN protein inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]18281512
D004317Doxorubicin[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein25824409
D004317Doxorubicingeldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16311509
D004317DoxorubicinGSTA1 protein inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16890185
D004317DoxorubicinIFNA1 protein promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17959036
D004317DoxorubicinLCS101 inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]25333773
D004317Doxorubicinpalbociclib inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]22751436
D004317DoxorubicinRB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]22751436
D004317DoxorubicinRBL2 protein inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]15585644
D004317DoxorubicinSB 203580 inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16843435
D004317DoxorubicinSB 216763 inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinTGFB1 protein promotes the reaction [Doxorubicin results in increased degradation of PARP1 protein]17418594
D004317DoxorubicinTHBS1 protein inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16962673
D004317DoxorubicinU 0126 promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]15557793
D004317Doxorubicinwortmannin promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17935137
D004317Doxorubicinzinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]19714248
D004317Doxorubicin"5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein]"19286953
D004317DoxorubicinABCC1 gene mutant form promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]26822305
D004317Doxorubicin[Doxorubicin co-treated with Curcumin] results in increased cleavage of PARP1 protein18006147
D004317DoxorubicinDoxorubicin promotes the reaction [AZD 6244 results in increased cleavage of PARP1 protein]17876044
D004317DoxorubicinDoxorubicin results in decreased activity of PARP1 protein20656019
D004317DoxorubicinDoxorubicin results in increased activity of PARP1 protein19286953
D004317DoxorubicinDoxorubicin results in increased cleavage of PARP1 protein10704466|2036388
D004317DoxorubicinDoxorubicin results in increased expression of PARP1 protein20144634
D004317DoxorubicinPARP1 gene mutant form inhibits the reaction [Doxorubicin results in increased phosphorylation of CDK2 protein]15861398
D004317DoxorubicinPARP1 gene mutant form promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]15861398
D004317DoxorubicinPARP1 gene mutant form promotes the reaction [Doxorubicin results in increased activity of CASP7 protein]15861398
D004317DoxorubicinPARP1 protein affects the susceptibility to Doxorubicin11861791
D004317DoxorubicinPARP1 protein promotes the reaction [Doxorubicin results in increased expression of BECN1 mRNA]19001878
D004317DoxorubicinPARP1 protein promotes the reaction [Doxorubicin results in increased expression of BECN1 protein]19001878
D004317DoxorubicinPARP1 protein promotes the reaction [Doxorubicin results in increased expression of BNIP3 mRNA]19001878
D004317DoxorubicinPARP1 protein promotes the reaction [Doxorubicin results in increased expression of CTSB mRNA]19001878
D004317DoxorubicinPARP1 protein promotes the reaction [Doxorubicin results in increased expression of CTSL mRNA]19001878
D004317DoxorubicinPARP1 protein results in increased uptake of Doxorubicin15861398
D004317DoxorubicinSilymarin inhibits the reaction [Doxorubicin results in increased expression of PARP1 protein]20144634
D004317DoxorubicinSTAT3 gene mutant form promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]24812279
D004317Doxorubicin[STAT3 gene mutant form results in increased susceptibility to Doxorubicin] which results in increased cleavage of PARP1 protein24812279
D004317Doxorubicintetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein]19286953
D004317DoxorubicinTRP53 protein mutant form affects the reaction [Doxorubicin results in increased cleavage of PARP1 protein]24812279
D004317DoxorubicinVerapamil inhibits the reaction [PARP1 gene mutant form results in decreased uptake of Doxorubicin]15861398
D004317Doxorubicin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]18775851
D004317Doxorubicin7-monohydroxyethylrutoside inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17285121
D004317DoxorubicinDoxorubicin results in increased cleavage of PARP1 protein16687611|1728512
D004317DoxorubicinDoxorubicin results in increased expression of and results in increased cleavage of PARP1 protein21194538
D004317DoxorubicinDoxorubicin results in increased expression of PARP1 protein12967636|2119453
D004317DoxorubicinHSPD1 protein inhibits the reaction [Doxorubicin results in increased expression of PARP1 protein]12967636
D004317DoxorubicinHSPE1 protein inhibits the reaction [Doxorubicin results in increased expression of PARP1 protein]12967636
D004317Doxorubicinkaempferol inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]22155320
D004317Doxorubicinpifithrin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16687611
D004317DoxorubicinQuercetin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]24902966
D004317DoxorubicinTNF protein promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17651020
D004317DoxorubicinU 0126 inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]18775851
C060327dracorhodindracorhodin analog results in increased cleavage of PARP1 protein15215653|1568447
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PARP1 protein]"28733231
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased cleavage of PARP1 protein"15802533|1799622
D004365Drugs, Chinese Herbal"arsenic trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of PARP1 protein]"28587418
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased cleavage of PARP1 protein"28587418
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D004533Egtazic Acid"[1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid co-treated with Egtazic Acid] inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]"29111403
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D004610Ellagic AcidEllagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]25247703
C034192ellipticineellipticine results in increased cleavage of PARP1 protein21843585
C010945embelinembelin results in increased cleavage of PARP1 protein24694877
D004640EmetineEmetine results in increased cleavage of PARP1 protein21256112
D004642Emodin2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased cleavage of PARP1 protein]27032576
D004642EmodinEmodin results in increased activity of PARP1 protein23848338
D004642EmodinEmodin results in increased cleavage of PARP1 protein27032576
D004642EmodinSB 203580 inhibits the reaction [Emodin results in increased cleavage of PARP1 protein]27032576
D004642Emodin[U 0126 co-treated with Emodin] results in increased cleavage of PARP1 protein27032576
D004642EmodinU 0126 inhibits the reaction [Emodin results in increased cleavage of PARP1 protein]27032576
C530049ent-1,3,6,11-tetrahydroxykaur-16-ene-15-one 3,11-diacetate"ent-1,3,6,11-tetrahydroxykaur-16-ene-15-one 3,11-diacetate results in increased cleavage of PARP1 protein"19509257
D004791Enzyme Inhibitors[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PARP1 protein23301498
D015251EpirubicinEpirubicin results in increased cleavage of PARP1 protein26646421
D015251Epirubicinpaeonol inhibits the reaction [Epirubicin results in increased cleavage of PARP1 protein]26646421
C045651epigallocatechin gallateCAT protein inhibits the reaction [[epigallocatechin gallate co-treated with arsenite] results in increased cleavage of PARP1 protein]26375285
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with arsenite] results in increased cleavage of PARP1 protein26375285
C045651epigallocatechin gallateepigallocatechin gallate affects the cleavage of PARP1 protein23954321
C045651epigallocatechin gallateepigallocatechin gallate inhibits the reaction [potassium chromate(VI) results in increased cleavage of and results in increased activity of PARP1 protein]22079256
C045651epigallocatechin gallateepigallocatechin gallate results in increased activity of PARP1 protein15657356
C045651epigallocatechin gallateepigallocatechin gallate results in increased cleavage of PARP1 protein15705601|1576464
C045651epigallocatechin gallateepigallocatechin gallate affects the activity of PARP1 protein25955525
C093787epothilone A[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA29117515
C093787epothilone Aepothilone A results in increased expression of PARP1 mRNA29117515
C093787epothilone ASodium Salicylate inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]29117515
C093787epothilone Atriciribine inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]29117515
C093787epothilone Atriciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA]29117515
C078846epoxomicinepoxomicin results in increased cleavage of PARP1 protein20153345
C078846epoxomicinquinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [epoxomicin results in increased cleavage of PARP1 protein]20153345
C048498erdosteineerdosteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]26193055
C529414erigeroflavanoneerigeroflavanone inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]19557877
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in increased cleavage of PARP1 protein23125191
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in increased expression of PARP1 protein modified form25895606
D000069347Erlotinib Hydrochlorideresveratrol promotes the reaction [Erlotinib Hydrochloride results in increased expression of PARP1 protein modified form]25895606
C007366erythritol anhydrideerythritol anhydride results in increased cleavage of PARP1 protein14998682
C007628esculetinesculetin results in increased cleavage of PARP1 protein26388407
C074283estradiol 3-benzoateestradiol 3-benzoate results in increased cleavage of PARP1 protein24316378
C074283estradiol 3-benzoateQuercetin inhibits the reaction [estradiol 3-benzoate results in increased cleavage of PARP1 protein]24316378
D004976Ethacrynic AcidAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
D004976Ethacrynic Acid[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein23082001
D004976Ethacrynic Acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
D004976Ethacrynic AcidGSTP1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
D004976Ethacrynic AcidMCL1 mutant form promotes the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
D004976Ethacrynic Acidpyrazolanthrone inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
D000431EthanolEthanol results in increased cleavage of PARP1 protein21410490|2437456
D000431EthanolSirolimus inhibits the reaction [Ethanol results in increased cleavage of PARP1 protein]21410490
D000431Ethanoldioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein]24146112
D000431EthanolEthanol results in increased cleavage of PARP1 protein22535522
D000431EthanolEthanol results in increased expression of PARP1 protein24146112
D000431Ethanoldioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein]24146112
D000431EthanolEthanol results in increased expression of PARP1 mRNA15353170
D000431EthanolEthanol results in increased expression of PARP1 protein24146112
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PARP1 mRNA17942748
C456800ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased cleavage of PARP1 protein15634644
D005047Etoposide"3',4'-dihydroxyflavone analog inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]"16014620
D005047EtoposideBCL2L1 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]8840993
D005047EtoposideBCL2 protein inhibits the reaction [Etoposide results in increased degradation of PARP1 protein]8840993
D005047Etoposide[CASP8 co-treated with TP53] affects the reaction [Etoposide results in increased cleavage of PARP1 protein]21801448
D005047EtoposideCD40LG protein inhibits the reaction [Etoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]16545138
D005047Etoposide[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]9454737
D005047EtoposideEtoposide promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]16545138
D005047EtoposideEtoposide results in increased cleavage of PARP1 protein12690110|1601462
D005047EtoposideEtoposide results in increased degradation of PARP1 protein8840993
D005047EtoposideHTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]16799960
D005047EtoposideNicotine inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]20457658
D005047EtoposidePTEN protein modified form promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]16807353
D005047EtoposidePTEN protein promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]16807353
D005047Etoposidewortmannin promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]17935137
D005047EtoposideEtoposide results in increased cleavage of PARP1 protein17516866
D005047EtoposideNiacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein]17516866
D005054EugenolEugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein]20434464
D000068338Everolimus[navitoclax co-treated with Everolimus] results in increased cleavage of PARP1 protein28947240
C049639evodiamineevodiamine promotes the reaction [TNF protein results in increased cleavage of PARP1 protein]15710601
C574336excavatolide Bexcavatolide B results in increased cleavage of PARP1 protein26790859
D018683Excitatory Amino Acid AgentsPARP1 protein affects the reaction [Zinc results in decreased uptake of Excitatory Amino Acid Agents]17728843
D018690Excitatory Amino Acid AgonistsExcitatory Amino Acid Agonists results in decreased expression of PARP1 protein19288225
D018690Excitatory Amino Acid AgonistsExcitatory Amino Acid Agonists results in increased activity of PARP1 protein19288225
D018690Excitatory Amino Acid AgonistsExcitatory Amino Acid Agonists results in increased cleavage of PARP1 protein24675465
D018690Excitatory Amino Acid AgonistsNiacinamide inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of PARP1 protein]19288225
D018690Excitatory Amino Acid AgonistsNiacinamide inhibits the reaction [Excitatory Amino Acid Agonists results in increased activity of PARP1 protein]19288225
D018690Excitatory Amino Acid Agonistsresveratrol inhibits the reaction [Excitatory Amino Acid Agonists results in increased cleavage of PARP1 protein]24675465
D018690Excitatory Amino Acid AgonistsSB 216763 inhibits the reaction [Excitatory Amino Acid Agonists results in increased cleavage of PARP1 protein]24675465
D015025ZearalenoneZearalenone results in decreased expression of PARP1 protein28089945
D015025ZearalenoneZearalenone results in increased cleavage of PARP1 protein24530352
C060802fangchinolinefangchinoline results in increased cleavage of PARP1 protein28754437
C069346fascaplysinefascaplysine analog results in increased cleavage of PARP1 protein28756150
C000499ferric oxideferric oxide analog results in increased cleavage of PARP1 protein27270449
C000499ferric oxideferric oxide results in decreased expression of and results in increased cleavage of PARP1 protein28993115
C000499ferric oxideferric oxide results in increased cleavage of PARP1 protein26991130
D000068876Fingolimod Hydrochloride3-methyladenine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod HydrochlorideAcetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod HydrochlorideBECN1 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod Hydrochloridebenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod HydrochlorideFingolimod Hydrochloride results in increased cleavage of PARP1 protein25939952
D000068876Fingolimod Hydrochloridenecrostatin-1 inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod Hydrochloridepifithrin inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod Hydrochloridepyrazolanthrone inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod HydrochlorideRIPK3 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
D000068876Fingolimod HydrochlorideSQSTM1 mutant form inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
C017875fisetinfisetin results in decreased activity of PARP1 protein17884996
C028610flavanoneflavanone results in increased cleavage of PARP1 protein22056764
D044950Flavanones3-methyladenine promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
D044950Flavanonesbafilomycin A1 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
D044950Flavanonesbenzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
D044950FlavanonesFlavanones results in increased cleavage of PARP1 protein21616090
D044950FlavanonesU 0126 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
C043562flavoneflavone results in increased cleavage of PARP1 protein15289867
D005419FlavonoidsFlavonoids results in decreased expression of PARP1 mRNA15465739
D005419FlavonoidsFlavonoids results in increased cleavage of PARP1 protein23063593
D005419FlavonoidsFlavonoids results in increased expression of PARP1 mRNA18035473
C548902FLLL 32FLLL 32 results in increased cleavage of PARP1 protein20712901
D005467FloxuridinePARP1 protein results in decreased susceptibility to Floxuridine21613406
C024352fludarabine[clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased cleavage of PARP1 protein20933509
C024352fludarabine[fludarabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein12780785
C108339fludioxonilfludioxonil results in increased expression of PARP1 protein23052036
C007738fluoranthenefluoranthene results in increased cleavage of PARP1 protein21132278
D005472Fluorouracil3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein]19116755
D005472Fluorouracilbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein]25940438
D005472FluorouracilCelecoxib inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]17461495
D005472Fluorouracil[Fluorouracil co-treated with Genistein] results in increased cleavage of PARP1 protein15896711
D005472FluorouracilFluorouracil promotes the reaction [gambogic acid results in decreased expression of PARP1 mRNA]19084572
D005472FluorouracilFluorouracil promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]19084572
D005472FluorouracilFluorouracil results in increased cleavage of and results in increased activity of PARP1 protein19116755
D005472FluorouracilFluorouracil results in increased cleavage of PARP1 protein15996812|1652565
D005472FluorouracilFluorouracil results in increased expression of PARP111300326
D005472FluorouracilFluorouracil results in increased expression of PARP1 mRNA28599477
D005472FluorouracilNicotine inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]24095863
D005472FluorouracilS100A11 mutant form promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]25940438
D005472Fluorouracil[S100A11 mutant form results in increased susceptibility to Fluorouracil] which results in increased cleavage of PARP1 protein25940438
D005472Fluorouracil[SM-1 compound co-treated with Fluorouracil] results in increased expression of PARP1 protein28599477
D005472FluorouracilSM-1 compound promotes the reaction [Fluorouracil results in increased expression of PARP1 mRNA]28599477
D005472FluorouracilTNFRSF10B mutant form inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]26544897
D005472FluorouracilTP53 protein promotes the reaction [Fluorouracil results in increased cleavage of PARP1 protein]17982676
D005472Fluorouracil3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein]19116755
D005472FluorouracilFluorouracil results in increased cleavage of and results in increased activity of PARP1 protein19116755
D005485FlutamideFlutamide results in increased expression of PARP1 mRNA24136188
D005492Folic AcidFolic Acid results in increased cleavage of PARP1 protein16728583
D005557FormaldehydeFormaldehyde results in increased expression of PARP1 protein modified form24140967
D005557FormaldehydeFormaldehyde results in decreased expression of PARP1 mRNA17285311
D005557FormaldehydeDDAH1 protein inhibits the reaction [Formaldehyde results in increased expression of PARP1 protein modified form]24140967
C058728fosbretabulin[3-methyladenine co-treated with fosbretabulin] results in increased cleavage of PARP1 protein24321340
C058728fosbretabulin3-methyladenine promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]24321340
C058728fosbretabulinbafilomycin A1 promotes the reaction [fosbretabulin results in increased cleavage of PARP1 protein]24321340
C058728fosbretabulinfosbretabulin results in increased cleavage of PARP1 protein24321340
D005632FructoseFructose results in increased expression of PARP1 protein28257781
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol results in increased cleavage of PARP1 protein]21732360
C070081fulvestrantfulvestrant inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]21732360
C056933fumonisin B1fumonisin B1 results in decreased cleavage of PARP1 protein25800559
C056933fumonisin B1fumonisin B1 inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]24448832
D005664FurazolidoneCDKN1A protein inhibits the reaction [Furazolidone results in increased phosphorylation of PARP1 protein]26687534
D005664FurazolidoneFurazolidone results in increased cleavage of PARP1 protein26687534
D005688Galactosamine[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein20558151
D005688Galactosaminegentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein]20558151
C037032galangingalangin results in increased cleavage of PARP1 protein18455702
D005707Gallic Acid"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Gallic Acid results in increased cleavage of PARP1 protein]"27060209
D005707Gallic AcidGallic Acid results in increased cleavage of PARP1 protein27060209
C052659gambogic acidAcetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]25824409
C052659gambogic acidAcetylcysteine inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]24373880
C052659gambogic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Bortezomib promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]]24291039
C052659gambogic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [gambogic acid promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]]24291039
C052659gambogic acidbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]24373880
C052659gambogic acidBortezomib promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]24291039
C052659gambogic acidFluorouracil promotes the reaction [gambogic acid results in decreased expression of PARP1 mRNA]19084572
C052659gambogic acidFluorouracil promotes the reaction [gambogic acid results in increased cleavage of PARP1 protein]19084572
C052659gambogic acid[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein25824409
C052659gambogic acidgambogic acid promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]24291039
C052659gambogic acidgambogic acid results in decreased expression of PARP1 mRNA19084572
C052659gambogic acidgambogic acid results in increased cleavage of PARP1 protein19084572|1946457
C052659gambogic acid[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein24373880
D017965gamma-Linolenic Acidgamma-Linolenic Acid results in increased cleavage of PARP1 protein10403056
C025473gamma-sitosterolgamma-sitosterol results in increased cleavage of PARP1 protein14612938
C054597garcinolgarcinol results in increased cleavage of PARP1 protein16052481
C000591222gardenin Bgardenin B results in increased cleavage of PARP1 protein27423764
C505531GCS-100GCS-100 results in increased cleavage of PARP1 protein16166312
C574276GDC-0973"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [GDC-0973 results in increased cleavage of PARP1 protein]"22084396
C574276GDC-0973"GDC-0973 promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased cleavage of PARP1 protein]"22084396
C574276GDC-0973GDC-0973 results in increased cleavage of PARP1 protein22084396
C419708gefitinibgefitinib affects the reaction [oxaliplatin results in increased cleavage of PARP1 protein]16243822
C419708gefitinibgefitinib results in increased cleavage of PARP1 protein23523951
C001277geldanamycingeldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16311509
C001277geldanamycingeldanamycin results in increased degradation of PARP1 protein17293044
C001277geldanamycinTretinoin inhibits the reaction [geldanamycin results in increased degradation of PARP1 protein]17293044
C056507gemcitabine[alvocidib co-treated with gemcitabine] results in increased cleavage of PARP1 protein15770523
C056507gemcitabinebenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [gemcitabine results in increased cleavage of PARP1 protein]17146438
C056507gemcitabinegemcitabine results in increased cleavage of PARP1 protein17146438|2689485
C056507gemcitabineSFN protein inhibits the reaction [gemcitabine results in increased cleavage of PARP1 protein]26894857
C056507gemcitabineYAP1 protein affects the reaction [gemcitabine results in increased cleavage of PARP1 protein]26894857
D019833Genistein[Fluorouracil co-treated with Genistein] results in increased cleavage of PARP1 protein15896711
D019833Genistein[Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein21078540
D019833GenisteinGenistein results in increased cleavage of PARP1 protein12791511|2107854
D019833Genistein[Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein21078540
D019833GenisteinGenistein results in increased cleavage of PARP1 protein21078540|2575627
D019833GenisteinGenistein inhibits the reaction [bisphenol A results in decreased cleavage of PARP1 protein]24884420
D019833GenisteinGenistein results in increased cleavage of PARP1 protein24884420
D005839GentamicinsAcetylcysteine inhibits the reaction [Gentamicins results in increased activity of PARP1 protein]11470263
D005839GentamicinsGentamicins results in increased activity of PARP1 protein11470263
D005839GentamicinsGentamicins results in increased expression of PARP1 mRNA22061828
C012997gentiopicrosidegentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein]20558151
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]21910007
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]21910007
C007845gingerolAcetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]25034532
C007845gingerol[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein25034532
C097367ginsenoside Rg3ginsenoside Rg3 analog inhibits the reaction [TGFB1 protein results in increased cleavage of PARP1 protein]24793912
C097367ginsenoside Rg3"ginsenoside Rg3 inhibits the reaction [cagA protein, Helicobacter pylori results in decreased cleavage of PARP1 protein]"26427350
C097367ginsenoside Rg3ginsenoside Rg3 results in increased cleavage of PARP1 protein22101440
D005944GlucosamineGlucosamine results in increased cleavage of PARP1 protein16850161
D005944Glucosaminepepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein]16850161
D005947GlucoseERCC1 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]22228707
D005947GlucoseERCC4 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]22228707
D005947Glucose[Glucose deficiency co-treated with Acetylcysteine] results in increased cleavage of PARP1 protein17309078
D005947Glucose[Glucose deficiency co-treated with CAT] results in increased cleavage of PARP1 protein17309078
D005947Glucose[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of PARP1 protein17309078
D005947GlucoseGlucose results in increased expression of PARP1 mRNA22228707
D005947GlucoseGlucose results in increased expression of PARP1 protein modified form24218232
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of PARP1 protein modified form]24218232
D005947GlucoseGlucose results in decreased expression of PARP1 mRNA21818840
D005947GlucoseGlucose results in increased activity of PARP1 protein18004065
D005947GlucoseGlucose results in increased cleavage of PARP1 protein22524206
D005947Glucose[INS1 protein co-treated with Glucose] results in increased activity of PARP1 protein18545258
D005947GlucoseQuercetin inhibits the reaction [Glucose results in increased cleavage of PARP1 protein]22524206
D005947Glucosesesamin inhibits the reaction [Glucose results in increased cleavage of PARP1 protein]22524206
D005947GlucoseSimvastatin inhibits the reaction [Glucose results in increased activity of PARP1 protein]18004065
D005947GlucoseSOD1 protein inhibits the reaction [[INS1 protein co-treated with Glucose] results in increased activity of PARP1 protein]18545258
C023847Glu-P-2Glu-P-2 results in decreased activity of PARP1 protein17072025
D005978GlutathioneGlutathione deficiency promotes the reaction [antimony trioxide results in increased cleavage of PARP1 protein]16112521
D005978Glutathione"Glutathione inhibits the reaction [1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane results in increased cleavage of PARP1 protein]"24515801
D005978GlutathioneGlutathione inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein]14660655
D005978Glutathione"Glutathione inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
D005978GlutathioneGlutathione inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]26887594
D005999Glycochenodeoxycholic AcidGlycochenodeoxycholic Acid results in increased cleavage of PARP1 protein25125499
C081021Go 6976"Go 6976 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
D006046GoldOrganogold Compounds promotes the reaction [Gold binds to PARP1 protein]21370912
C103280goniothalamingoniothalamin results in increased cleavage of PARP1 protein18771661|2181043
C103280goniothalaminpifithrin inhibits the reaction [goniothalamin results in increased cleavage of PARP1 protein]21810437
C103280goniothalaminTP53 mutant form inhibits the reaction [goniothalamin results in increased cleavage of PARP1 protein]21810437
C059922gossypetin"gossypetin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased cleavage of PARP1 protein]"25622137
C059922gossypetingossypetin results in decreased activity of PARP1 protein17884996
D006146GuanidinesGuanidines analog results in increased cleavage of PARP1 protein23147571
C479979GW0742GW0742 promotes the reaction [Indomethacin results in increased cleavage of PARP1 protein]21400612
C479979GW0742GW0742 promotes the reaction [sulindac sulfide results in increased cleavage of PARP1 protein]21400612
C479979GW0742GW0742 results in increased cleavage of PARP1 protein27427494
C473027GW 3965GW 3965 inhibits the reaction [Palmitates results in increased cleavage of PARP1 protein]21209018
C412815GW 4064GW 4064 results in decreased phosphorylation of PARP1 protein23178280
C425931GW 501516GW 501516 promotes the reaction [Indomethacin results in increased cleavage of PARP1 protein]21400612
C001330hellebrigeninhellebrigenin results in increased activity of PARP1 protein24954031
C020754herbimycinherbimycin results in increased cleavage of PARP1 protein11035063
C482862heyneanol Aheyneanol A results in increased cleavage of PARP1 protein16675471
C005499honokiolhonokiol results in increased cleavage of PARP1 protein15802533
D017313Fenretinide2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313Fenretinide2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313FenretinideAcetylcysteine inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
D017313FenretinideAscorbic Acid inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313FenretinideBI D1870 inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
D017313Fenretinidebisindolylmaleimide I inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313FenretinideButylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313FenretinideDeoxyglucose inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
D017313FenretinideFenretinide affects the expression of PARP1 mRNA16570282
D017313Fenretinide[Fenretinide co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein17273769
D017313FenretinideFenretinide promotes the reaction [TNF protein results in increased cleavage of PARP1 protein]16230421
D017313FenretinideFenretinide results in decreased cleavage of PARP1 protein17159502
D017313FenretinideFenretinide results in increased cleavage of PARP1 protein15735044|1640784
D017313FenretinideMAPK8 protein promotes the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313Fenretinidepyrazolanthrone inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
D017313FenretinideS-ethyl glutathione inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
D017313FenretinideU 0126 inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
C503536HS-1199HS-1199 results in increased cleavage of PARP1 protein16077913|2039655
C479128HS 1200HS 1200 results in increased cleavage of PARP1 protein16077913|1856564
C479128HS 1200HS 1200 results in increased degradation of PARP1 protein12969788
D012701SerotoninPARP1 affects the abundance of Serotonin21990073
C062018HU 211AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein]19509271
C062018HU 211HU 211 results in increased cleavage of PARP1 protein19509271
D006830Hydralazine[Hydralazine co-treated with Valproic Acid] results in increased expression of PARP1 mRNA17183730
D006835HydrazonesHydrazones results in increased cleavage of PARP1 protein22056764
D006859HydrogenHydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein]26271894
D006861Hydrogen Peroxide3-aminobenzamide inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]11217149
D006861Hydrogen Peroxide[BIN1 protein binds to PARP1 protein] inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]21447800
D006861Hydrogen Peroxidedimethylarsinous acid inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]17011244
D006861Hydrogen PeroxideHydrogen Peroxide affects the reaction [PARP1 protein mutant form affects the abundance of NAD]27694308
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]24750999
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of PARP1 protein11217149|2095358
D006861Hydrogen PeroxideHydrogen Peroxide results in increased ADP-ribosylation of PARP1 protein27694308
D006861Hydrogen PeroxideHydrogen Peroxide results in increased cleavage of PARP1 protein19815691|2906131
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of PARP1 protein modified form16709600|2372686
D006861Hydrogen Peroxidemonomethylarsonous acid inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]17011244
D006861Hydrogen PeroxidePARP1 protein affects the susceptibility to Hydrogen Peroxide19111594|2769430
D006861Hydrogen PeroxidePARP1 protein mutant form promotes the reaction [Hydrogen Peroxide results in increased abundance of Poly Adenosine Diphosphate Ribose]27694308
D006861Hydrogen PeroxidePARP1 protein promotes the reaction [Hydrogen Peroxide results in decreased abundance of NAD]27694308
D006861Hydrogen PeroxidePARP1 protein promotes the reaction [Hydrogen Peroxide results in increased abundance of Poly Adenosine Diphosphate Ribose]27694308
D006861Hydrogen Peroxide[sodium arsenite co-treated with Hydrogen Peroxide] results in increased cleavage of PARP1 protein18977016
D006861Hydrogen PeroxideTH protein inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]19815691
D006861Hydrogen Peroxideveliparib inhibits the reaction [Hydrogen Peroxide affects the reaction [PARP1 protein mutant form affects the abundance of NAD]]27694308
D006861Hydrogen Peroxidebenzamide inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D006861Hydrogen Peroxide[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Hydrogen Peroxide11593040
D006861Hydrogen Peroxideerigeroflavanone inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]19557877
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of PARP1 protein11593040|2481448
D006861Hydrogen Peroxide[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD11593040
D006861Hydrogen PeroxideHydrogen Peroxide results in increased cleavage of PARP1 protein15876423|1955787
D006861Hydrogen PeroxideHydrolyzable Tannins inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D006861Hydrogen Peroxideolaparib inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]24814482
D006861Hydrogen PeroxidePARP1 gene mutant form results in decreased susceptibility to Hydrogen Peroxide17438151
D006861Hydrogen PeroxidePARP1 protein promotes the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]20878536
D006861Hydrogen PeroxidePARP1 protein promotes the reaction [Hydrogen Peroxide results in increased cleavage of CASP6 protein]20878536
D006861Hydrogen PeroxidePARP1 protein promotes the reaction [Hydrogen Peroxide results in increased cleavage of CASP9 protein]20878536
D006861Hydrogen PeroxidePARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium]20878536
D006861Hydrogen PeroxidePARP1 protein results in increased susceptibility to Hydrogen Peroxide20878536
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]15876423
D006861Hydrogen PeroxideSOD2 mutant form inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]24740755
D006861Hydrogen Peroxidecalycopterin results in decreased susceptibility to [Hydrogen Peroxide results in increased cleavage of PARP1 protein]22081883
D006861Hydrogen Peroxidecalycopterin results in decreased susceptibility to [Hydrogen Peroxide results in increased expression of PARP1 protein modified form]22081883
D006861Hydrogen PeroxideCAT protein inhibits the reaction [[Rotenone results in increased abundance of Hydrogen Peroxide] which results in increased cleavage of PARP1 protein]25304210
D006861Hydrogen PeroxideFOXO1 mRNA inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]26354380
D006861Hydrogen PeroxideHydrogen Peroxide results in increased cleavage of PARP1 protein14505808|2208188
D006861Hydrogen PeroxideHydrogen Peroxide results in increased degradation of PARP1 protein16157298
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of PARP1 protein modified form22081883
D006861Hydrogen PeroxideQuercetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]14505808
D006861Hydrogen Peroxide[Rotenone results in increased abundance of Hydrogen Peroxide] which results in increased cleavage of PARP1 protein25304210
D047348Hydrolyzable TanninsHydrolyzable Tannins inhibits the reaction [[Hydrogen Peroxide results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D047348Hydrolyzable TanninsHydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
C031927hydroquinone3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein]26047893
C031927hydroquinoneDoxorubicin inhibits the reaction [hydroquinone results in decreased expression of PARP1 protein]26047893
C031927hydroquinonehydroquinone affects the expression of PARP1 protein26047893
C031927hydroquinonehydroquinone promotes the reaction [PARP1 protein binds to and results in increased ADP-ribosylation of and results in increased expression of HRAS protein]26047893
C031927hydroquinonehydroquinone results in increased cleavage of PARP1 protein19064679
C031927hydroquinonehydroquinone results in increased expression of PARP1 protein28263894
C031927hydroquinonePARP1 protein affects the susceptibility to hydroquinone28444915
C031927hydroquinone[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of and affects the activity of CASP3 protein28444915
C031927hydroquinone[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of BCL2 protein28444915
C031927hydroquinone[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of FAS protein28444915
C031927hydroquinone[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of KRAS protein28444915
C031927hydroquinone[PARP1 protein affects the susceptibility to hydroquinone] which affects the expression of TP53 protein28444915
C031927hydroquinonePARP1 protein promotes the reaction [hydroquinone results in increased expression of ATG5 mRNA]28263894
C031927hydroquinonePARP1 protein promotes the reaction [hydroquinone results in increased expression of BECN1 mRNA]28263894
C031927hydroquinonePARP1 protein promotes the reaction [hydroquinone results in increased expression of HRAS protein]26047893
C031927hydroquinonePARP1 protein results in increased susceptibility to hydroquinone26047893
C031927hydroquinoneWRN protein inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein]19064679
D006877Hydroxamic AcidsHydroxamic Acids results in increased cleavage of PARP1 protein27163855
C005044hydroxyethyl methacrylate3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [hydroxyethyl methacrylate results in increased cleavage of PARP1 protein]28184909
C005044hydroxyethyl methacrylatehydroxyethyl methacrylate results in increased cleavage of PARP1 protein28184909
C021304hyperoside[Quercetin co-treated with hyperoside] results in increased cleavage of PARP1 protein24173369|2535454
C000623387HZ-6d compoundHZ-6d compound results in increased expression of PARP1 protein modified form28919514
C552946idelalisib[palbociclib results in increased susceptibility to idelalisib] which results in increased cleavage of PARP1 protein23676220
C467077ilimaquinoneilimaquinone promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]24930757
C467077ilimaquinoneilimaquinone results in increased cleavage of PARP1 protein24930757
C467077ilimaquinone[ilimaquinone results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of PARP1 protein24930757
D000068877Imatinib Mesylate[BIX 01294 results in increased susceptibility to Imatinib Mesylate] which results in increased cleavage of PARP1 protein25079219
D000068877Imatinib MesylateImatinib Mesylate promotes the reaction [ON 01910 results in increased cleavage of PARP1 protein]26008977
D000068877Imatinib MesylateImatinib Mesylate results in increased cleavage of PARP1 protein26008977
D000068877Imatinib MesylateON 01910 promotes the reaction [Imatinib Mesylate results in increased cleavage of PARP1 protein]26008977
D000068877Imatinib Mesylate[PLK1 mutant form results in increased susceptibility to Imatinib Mesylate] which results in increased cleavage of PARP1 protein26008977
D000068877Imatinib MesylatePLK1 protein affects the reaction [Imatinib Mesylate results in increased cleavage of PARP1 protein]26008977
C113661imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III)imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III) inhibits the reaction [Zinc binds to PARP1 protein]21370912
C113661imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III)imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III) promotes the reaction [Ruthenium binds to PARP1 protein]21370912
C113661imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III)imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III) results in decreased activity of PARP1 protein21370912
D007099ImipramineImipramine results in increased cleavage of PARP1 protein10487422
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in increased cleavage of PARP1 protein"21132278
C428264indioside Dindioside D results in increased cleavage of PARP1 protein18376857
C016517indole-3-carbinolindole-3-carbinol promotes the reaction [TNF protein results in increased cleavage of PARP1 protein]15811958
C014612indolebutyric acidindolebutyric acid analog results in increased cleavage of PARP1 protein23499788
C015292indolepropionic acidindolepropionic acid analog results in increased cleavage of PARP1 protein23499788
D007213IndomethacinGW0742 promotes the reaction [Indomethacin results in increased cleavage of PARP1 protein]21400612
D007213IndomethacinGW 501516 promotes the reaction [Indomethacin results in increased cleavage of PARP1 protein]21400612
D007213IndomethacinIndomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2126186
D007213IndomethacinIndomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]21882223
D007213IndomethacinIndomethacin promotes the reaction [LTA protein results in increased cleavage of PARP1 protein]17873517
D007213IndomethacinIndomethacin results in increased cleavage of PARP1 protein11532860|1266350
C572449INK128INK128 results in increased cleavage of PARP1 protein26536665
D019807Iodoacetic AcidIodoacetic Acid results in increased expression of PARP1 protein modified form25944804
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PARP1 mRNA25613284
C506002ircinin-1ircinin-1 results in increased cleavage of PARP1 protein16163705
D0150561-Methyl-3-isobutylxanthine[INS1 protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of PARP1 protein2523799
C040920isoliquiritigeninbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of PARP1 protein]23747687
C040920isoliquiritigeninisoliquiritigenin results in increased cleavage of PARP1 protein23747687
C575995isomenthoneisomenthone inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]22796318
C477508jaceosidinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]27729209
C477508jaceosidinCFLAR protein inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]27729209
C477508jaceosidinjaceosidin results in increased cleavage of PARP1 protein27729209
C477508jaceosidinMCL1 protein inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein]27729209
C098607JP8 aviation fuelJP8 aviation fuel results in increased ADP-ribosylation of PARP1 protein16690985
C098607JP8 aviation fuelJP8 aviation fuel results in increased expression of and results in increased activity of PARP1 protein17395016
C561695(+)-JQ1 compound[BCL2L1 protein co-treated with RAD51 protein] inhibits the reaction [[GNAQ gene mutant form results in increased susceptibility to (+)-JQ1 compound] which results in increased cleavage of PARP1 protein]26397223
C561695(+)-JQ1 compoundCDKN1C mutant form inhibits the reaction [[(+)-JQ1 compound co-treated with vorinostat] results in increased cleavage of PARP1 protein]26390243
C561695(+)-JQ1 compound[GNAQ gene mutant form results in increased susceptibility to (+)-JQ1 compound] which results in increased cleavage of PARP1 protein26397223
C561695(+)-JQ1 compound(+)-JQ1 compound affects the cleavage of PARP1 protein26051217
C561695(+)-JQ1 compound(+)-JQ1 compound analog promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]26415225
C561695(+)-JQ1 compound[(+)-JQ1 compound co-treated with vorinostat] results in increased cleavage of PARP1 protein26390243
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [ponatinib results in increased cleavage of PARP1 protein]25053825
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [quizartinib results in increased cleavage of PARP1 protein]25053825
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]26415225
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased cleavage of PARP1 protein22904298|2312962
C561695(+)-JQ1 compound[KRAS gene mutant form results in increased susceptibility to (+)-JQ1 compound] which results in increased cleavage of PARP1 protein24045185
C561695(+)-JQ1 compoundponatinib promotes the reaction [(+)-JQ1 compound results in increased cleavage of PARP1 protein]25053825
C561695(+)-JQ1 compoundquizartinib promotes the reaction [(+)-JQ1 compound results in increased cleavage of PARP1 protein]25053825
C561695(+)-JQ1 compoundSTK11 gene mutant form inhibits the reaction [[KRAS gene mutant form results in increased susceptibility to (+)-JQ1 compound] which results in increased cleavage of PARP1 protein]24045185
C561695(+)-JQ1 compound[STK11 protein results in increased susceptibility to (+)-JQ1 compound] which results in increased cleavage of PARP1 protein24045185
C410337K 7174K 7174 results in decreased expression of PARP1 mRNA24086573
C006552kaempferol"3',4'-dihydroxyflavone analog inhibits the reaction [kaempferol results in increased cleavage of PARP1 protein]"16014620
C006552kaempferolkaempferol results in increased cleavage of PARP1 protein16014620
C006552kaempferolkaempferol inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]22155320
C046438kahweol acetatepyrazolanthrone results in increased susceptibility to [[TNFSF10 protein co-treated with kahweol acetate] results in increased cleavage of PARP1 protein]20403343
C046438kahweol acetate[TNFSF10 protein co-treated with kahweol acetate] results in increased cleavage of PARP1 protein20403343
C046438kahweol acetateBCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with kahweol acetate] results in increased cleavage of PARP1 protein]20403343
C510621KCC 009KCC 009 results in increased cleavage of PARP1 protein16170020
C410027KNK 437KNK 437 promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]19371599
C490728lapatinib[lapatinib co-treated with bafilomycin A] results in increased cleavage of PARP1 protein25981168
C490728lapatinib[lapatinib co-treated with concanamycin A] results in increased cleavage of PARP1 protein25981168
C490728lapatiniblapatinib results in increased cleavage of PARP1 protein25221644
C000600161LCS101LCS101 inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]25333773
C000600161LCS101LCS101 results in decreased expression of PARP1 protein25333773
D007854LeadLead affects the expression of PARP1 mRNA28903495
C008261lead acetatelead acetate results in decreased expression of PARP1 mRNA21829687
D017705LignansLignans analog results in increased cleavage of PARP1 protein26620693
C002385linsidominelinsidomine results in decreased expression of PARP1 protein12880480
C002385linsidomineSelegiline inhibits the reaction [linsidomine results in decreased expression of PARP1 protein]12880480
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased cleavage of PARP1 protein"26470730
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased activity of PARP1 protein"19962977
D008070Lipopolysaccharides[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein20558151
D008070Lipopolysaccharidesgentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein]20558151
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of PARP1 protein modified form23170834
D008070Lipopolysaccharidesnotoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein modified form]23170834
D008070LipopolysaccharidesPARP1 gene mutant form inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]17438151
D008070LipopolysaccharidesPARP1 gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]17438151
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of PARP1 protein24973090
D008070LipopolysaccharidesSialic Acids inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein]24973090
D008094LithiumLithium inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]17849503
D018021Lithium ChlorideLithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]28343033
D018021Lithium ChlorideLithium Chloride promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
D008095Lithocholic Acid3-aminobenzamide inhibits the reaction [Lithocholic Acid analog results in increased activity of PARP1 protein]2120135
D008095Lithocholic AcidLithocholic Acid analog results in increased activity of PARP1 protein2120135
C000589248LL-202LL-202 results in increased cleavage of PARP1 protein24752227
C501175LM-16852-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[LM-1685 co-treated with carboxyamido-triazole] results in increased cleavage of PARP1 protein]15867384
C581034longikaurin Alongikaurin A results in increased expression of PARP1 protein modified form28801140
D008148LovastatinLovastatin analog results in increased cleavage of PARP1 protein26863638
D047311Luteolin[Luteolin co-treated with Paclitaxel] results in decreased expression of PARP1 protein24525192
D047311LuteolinLuteolin results in increased cleavage of PARP1 protein12168845
C094099LY 293111LY 293111 results in increased cleavage of PARP1 protein16151469
C094099LY 293111pyrazolanthrone inhibits the reaction [LY 293111 results in increased cleavage of PARP1 protein]16151469
C015329lycopenelycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein]23076637
C008301lysophosphatidylethanolaminelysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in increased activity of PARP1 protein]25125499
C048341mafosfamideBCL2 protein inhibits the reaction [mafosfamide results in increased cleavage of PARP1 protein]11723234
C048341mafosfamidemafosfamide results in increased cleavage of PARP1 protein11723234
C569869malondialdehyde-low density lipoprotein, human"gossypetin inhibits the reaction [malondialdehyde-low density lipoprotein, human results in increased cleavage of PARP1 protein]"25622137
C569869malondialdehyde-low density lipoprotein, human"malondialdehyde-low density lipoprotein, human results in increased cleavage of PARP1 protein"25622137
C065861malvidinmalvidin results in increased cleavage of PARP1 protein15964118
D008345Manganese[Manganese co-treated with NGF protein] results in increased cleavage of PARP1 protein25791630
D008345ManganeseManganese results in increased cleavage of PARP1 protein25448048|2579163
D008345ManganesePPM1D mutant form promotes the reaction [[Manganese co-treated with NGF protein] results in increased cleavage of PARP1 protein]25791630
D008345ManganesePPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased cleavage of PARP1 protein]25791630
C025340manganese chloride[Plant Extracts co-treated with manganese chloride] affects the cleavage of PARP1 protein26064043
C025340manganese chloridebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [manganese chloride results in increased cleavage of PARP1 protein]21704098
C025340manganese chloridemanganese chloride results in increased cleavage of PARP1 protein21704098
C021053mangostinmangostin results in increased cleavage of PARP1 protein23954321
C054474manumycinAcetylcysteine inhibits the reaction [manumycin results in increased cleavage of PARP1]19409983
C054474manumycinmanumycin results in increased cleavage of PARP119409983
C054474manumycinmanumycin results in increased cleavage of PARP1 protein14625852
C054474manumycinQuercetin promotes the reaction [manumycin results in increased cleavage of PARP1 protein]14625852
C034244matrinearsenic trioxide promotes the reaction [matrine results in increased cleavage of PARP1 protein]23700110
C034244matrinematrine promotes the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]23700110
C034244matrinematrine results in increased cleavage of PARP1 protein23700110
D008549MelarsoprolMelarsoprol results in increased cleavage of PARP1 protein15314284
D008555MelittenMelitten inhibits the reaction [TGFB1 protein results in increased cleavage of PARP1 protein]21871910
D008627Mercuric ChlorideMercuric Chloride results in increased cleavage of PARP1 protein11068922|1250452
D008627Mercuric ChlorideMercuric Chloride results in increased activity of PARP1 protein20006636
D008627Mercuric ChlorideAcetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein]22909951
D008627Mercuric Chloride[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein22909951
D008687Metformin[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA29117515
D008687MetforminMetformin results in increased expression of PARP1 mRNA29117515
D008687MetforminSodium Salicylate promotes the reaction [Metformin results in increased expression of PARP1 mRNA]29117515
D008687Metformintriciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA]29117515
D008687MetforminMetformin inhibits the reaction [Dietary Fats results in increased expression of and results in increased cleavage of PARP1 protein]27551045
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]26524635
D008694MethamphetamineMethamphetamine results in decreased cleavage of PARP1 protein26524635
D008694MethamphetamineBBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]26524635
D008694MethamphetamineCASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]25631491
D008694MethamphetamineDDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]26825372
D008694MethamphetamineIGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of PARP1 protein]25127757
D008694MethamphetamineMethamphetamine results in decreased cleavage of PARP1 protein26524635
D008694MethamphetamineMethamphetamine results in increased activity of PARP1 protein25127757
D008694MethamphetamineMethamphetamine results in increased cleavage of PARP1 protein25631491
D008694MethamphetamineMethamphetamine results in increased expression of PARP1 protein modified form26825372|2834113
D008694Methamphetaminewedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]25631491
D008727MethotrexateESRRA protein inhibits the reaction [Methotrexate results in increased cleavage of PARP1 protein]24967384
D008727MethotrexateMethotrexate results in increased cleavage of PARP1 protein17286800|2496738
C013598methoxyacetic acid[1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of PARP1 protein26006246
D008730MethoxsalenMethoxsalen inhibits the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form]22743290
C445068methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate"methyl 2-cyano-3,12-dioxoolean-1,9-dien-28-oate results in increased cleavage of PARP1 protein"17363558|2524627
C587228methyl 3-hydroxyimino-11-oxoolean-12-en-28-oatemethyl 3-hydroxyimino-11-oxoolean-12-en-28-oate results in increased activity of PARP1 protein24291674
C108732methyl-beta-cyclodextrinmethyl-beta-cyclodextrin inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
C042405methyl caffeatemethyl caffeate binds to and results in increased activity of PARP1 protein26415618
D008748Methylcholanthrene"Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of PARP1 protein]"11999409
C005223methyleugenolmethyleugenol results in increased cleavage of PARP1 protein28818686
C000614724methyleugenol-2',3'-epoxide"methyleugenol-2',3'-epoxide results in increased cleavage of PARP1 protein"28818686
D012862SkatoleSkatole results in increased cleavage of PARP1 protein19700606
C072239methyl jasmonatemethyl jasmonate metabolite promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]22079975
C004925methylmercuric chloridemethylmercuric chloride results in increased cleavage of PARP1 protein11068922
C020771methylmercury hydroxidemethylmercury hydroxide results in increased expression of PARP1 mRNA20493249
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of PARP1 mRNA23649840
D008741Methyl MethanesulfonatePARP1 protein affects the susceptibility to Methyl Methanesulfonate19111594
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of PARP1 mRNA"20188158
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased cleavage of PARP1 protein"26068050
D008769MethylnitronitrosoguanidinePARP1 protein results in increased susceptibility to Methylnitronitrosoguanidine22001597
D008769Methylnitronitrosoguanidinebenzamide inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D008769Methylnitronitrosoguanidine[benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine11593040
D008769MethylnitronitrosoguanidineEugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein]20434464
D008769MethylnitronitrosoguanidineHydrolyzable Tannins inhibits the reaction [[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD]11593040
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine affects the cleavage of PARP1 protein20434464
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased activity of PARP1 protein11593040
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine results in increased activity of PARP1 protein] which results in decreased abundance of NAD11593040
D008770MethylnitrosoureaPARP1 gene mutant form results in increased susceptibility to Methylnitrosourea15282315
D008770MethylnitrosoureaPARP1 protein affects the reaction [Methylnitrosourea affects the activity of TRP53 protein]11850828
D008770MethylnitrosoureaPARP1 protein affects the reaction [Methylnitrosourea affects the expression of TRP53 protein]11850828
D008770MethylnitrosoureaPARP1 protein affects the susceptibility to Methylnitrosourea11850828
D008770MethylnitrosoureaPARP1 protein promotes the reaction [Methylnitrosourea affects the metabolism of SOD2 protein]16052507
D008770MethylnitrosoureaMethylnitrosourea results in increased activity of PARP1 protein16168987
D008770MethylnitrosoureaNiacinamide inhibits the reaction [Methylnitrosourea results in increased activity of PARP1 protein]16168987
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein20946892|2480643
D0156551-Methyl-4-phenylpyridinium"8-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]"20946892
D0156551-Methyl-4-phenylpyridiniumMTERF4 protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]26102036
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein20946892
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of PARP1 protein26558463
D0156551-Methyl-4-phenylpyridinium"8-phenyl-6a,7,8,9,9a,10-hexahydro-6H-isoindolo(5,6-g)quinoxaline-7,9-dione inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]"20946892
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein24875324
D0156551-Methyl-4-phenylpyridiniumPlant Preparations inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]24875324
D0156551-Methyl-4-phenylpyridiniumPolysaccharides inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]24875324
C008493methylselenic acid"[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of PARP1 protein"18444175
C008493methylselenic acidAKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
C008493methylselenic acidBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
C008493methylselenic acid[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein17339365
C008493methylselenic acidHSPA5 protein inhibits the reaction [methylselenic acid results in increased cleavage of PARP1 protein]16204082
C008493methylselenic acidmethylselenic acid results in increased cleavage of PARP1 protein15845651|1620408
C008493methylselenic acidSB 216763 inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
C008493methylselenic acidmethylselenic acid results in increased cleavage of PARP1 protein19276161
D014290MetipranololMetipranolol inhibits the reaction [Zinc results in decreased expression of PARP1 protein]16799065
D014290MetipranololMetipranolol inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein]16799065
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]21910007
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]20045437
D008798Mevalonic AcidMevalonic Acid inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]21910007
C011309mezerein3-aminobenzamide inhibits the reaction [mezerein results in increased activity of PARP1 protein]2120135
C011309mezereinmezerein results in increased activity of PARP1 protein2120135|2126186
D015735MifepristoneMifepristone results in increased cleavage of PARP1 protein16525653
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone results in increased cleavage of PARP1 protein]16644695
D016685MitomycinCDKN1A mutant form inhibits the reaction [Chloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein]]15905168
D016685MitomycinChloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein]15905168
D016685MitomycinMitomycin promotes the reaction [Ouabain results in increased cleavage of PARP1 protein]24124520
D016685MitomycinMitomycin results in increased activity of PARP1 protein15905168
D016685MitomycinMitomycin results in increased cleavage of PARP1 protein24124520
D016685MitomycinOuabain promotes the reaction [Mitomycin results in increased cleavage of PARP1 protein]24124520
D016685MitomycinPARP1 protein results in decreased susceptibility to Mitomycin28757444
D008942MitoxantroneBCL2L1 protein inhibits the reaction [Mitoxantrone results in increased degradation of PARP1 protein]8840993
D008942MitoxantroneBCL2 protein inhibits the reaction [Mitoxantrone results in increased degradation of PARP1 protein]8840993
D008942Mitoxantrone[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein15582267
C550258MLN 8237MLN 8237 results in increased cleavage of PARP1 protein21291867
C406082monomethylarsonous acidmonomethylarsonous acid inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]17011244
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased activity of PARP1 protein19699219|2192553
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of PARP1 mRNA21925530
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of PARP1 protein21925530
C406082monomethylarsonous acidZinc inhibits the reaction [monomethylarsonous acid results in decreased activity of PARP1 protein]21925530
C008548morinmorin results in increased expression of PARP1 mRNA28689916
C523799MRK 003MRK 003 results in increased cleavage of PARP1 protein17804716
C568376MT19c compoundMT19c compound results in increased cleavage of PARP1 protein21803404
D009151Mustard Gasacetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of PARP1 protein]12482751
D009151Mustard GasBRCA2 protein inhibits the reaction [Mustard Gas results in increased cleavage of PARP1 protein]20435105
D009151Mustard GasCALM1 protein promotes the reaction [Mustard Gas results in increased cleavage of and results in increased activity of PARP1 protein]16935404
D009151Mustard GasFADD protein affects the reaction [Mustard Gas results in increased cleavage of PARP1 protein]12482751
D009151Mustard GasMustard Gas promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]12482751
D009151Mustard GasMustard Gas results in decreased expression of PARP1 mRNA25102026
D009151Mustard GasMustard Gas results in increased cleavage of and results in increased activity of PARP1 protein16935404
D009151Mustard GasMustard Gas results in increased cleavage of PARP1 protein11886524|1248275
D009151Mustard GasPARP1 protein affects the reaction [Mustard Gas affects the activity of CASP3 protein]11886524
D009151Mustard Gaspifithrin promotes the reaction [Mustard Gas results in increased cleavage of PARP1 protein]25448276
D009151Mustard GasPARP1 protein inhibits the reaction [Mustard Gas results in increased activity of CASP3 protein]11886524
D009151Mustard GasMustard Gas results in increased cleavage of PARP1 protein20659490
C040015myricetinmyricetin results in decreased activity of PARP1 protein17884996
C040015myricetinmyricetin results in increased cleavage of PARP1 protein15748703
C005246myristicinmyristicin results in increased cleavage of PARP1 protein24792648
C080955N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamideN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein]16230411
C078131N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamideN-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
C000594115N'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazideN'-(3-bromo-4-hydroxybenzylidene)-2-(9-oxo-10(9H)-acridinyl)acetohydrazide affects the cleavage of PARP1 protein24748653
C488176N-acetyl-S-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl esterN-acetyl-S-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester results in increased cleavage of PARP1 protein21097689
C568519N-alpha-(2-carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)ornithine amideN-alpha-(2-carboxyl)benzoyl-N5-(2-fluoro-1-iminoethyl)ornithine amide results in increased cleavage of PARP1 protein21882827
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased cleavage of PARP1 protein"24929217
C005273naringeninnaringenin results in increased cleavage of PARP1 protein27838343
C528561navitoclax[MTOR protein affects the susceptibility to navitoclax] which affects the cleavage of PARP1 protein28947240
C528561navitoclax[navitoclax co-treated with Everolimus] results in increased cleavage of PARP1 protein28947240
C528561navitoclaxnavitoclax results in increased cleavage of PARP1 protein28947240
C101954N-caproylsphingosineN-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]10811113
C101954N-caproylsphingosine[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]10811113
C498045NCX 4040NCX 4040 results in increased cleavage of PARP1 protein16282376
C507699necrostatin-1necrostatin-1 inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
C524653nectandrin-Bnectandrin-B inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]27511913
C552435N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide"N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide promotes the reaction [Oxygen deficiency results in increased cleavage of PARP1 protein]"20530905
D009525Niacin[Niacin co-treated with Ubiquinone co-treated with Riboflavin] results in increased expression of PARP1 protein18377693
D009525NiacinNiacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein]17516866
D009532Nickelbafilomycin A1 promotes the reaction [Nickel results in increased cleavage of PARP1 protein]28330870
D009532NickelBECN1 protein promotes the reaction [Nickel results in increased cleavage of PARP1 protein]28330870
D009532Nickelbenzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [Nickel results in increased cleavage of PARP1 protein]28330870
D009532NickelNickel results in decreased expression of PARP1 mRNA23195993
D009532NickelNickel results in increased cleavage of PARP1 protein28330870
D009532NickelPARP1 protein modified form binds to Nickel25549802
C022838nickel chlorideAcetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]]22172632
C022838nickel chlorideAcetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]]22172632
C022838nickel chlorideAcetylcysteine inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]22172632
C022838nickel chloridecobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]22172632
C022838nickel chloridenickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]22172632
C022838nickel chloridenickel chloride results in increased cleavage of PARP1 protein21828359|2217263
C022838nickel chloride[TP53 mutant form results in decreased susceptibility to nickel chloride] which results in decreased cleavage of PARP1 protein23566959
C022838nickel chloridealpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]24448832
C022838nickel chloridefumonisin B1 inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]24448832
C022838nickel chloridenickel chloride results in increased cleavage of PARP1 protein21843586|2444883
C022838nickel chloridepyrazolanthrone inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]21843586
C028007nickel monoxidenickel monoxide analog results in increased cleavage of PARP1 protein27270449
C028007nickel monoxidenickel monoxide results in increased cleavage of PARP1 protein21828359
C028007nickel monoxideOxygen deficiency inhibits the reaction [nickel monoxide analog results in increased cleavage of PARP1 protein]27270449
C029938nickel sulfate3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]]20493934
C029938nickel sulfatenickel sulfate inhibits the reaction [Potassium Dichromate results in increased cleavage of and results in increased activity of PARP1 protein]20493934
C029938nickel sulfatenickel sulfate results in increased cleavage of and results in increased activity of PARP1 protein20493934
C029938nickel sulfatenickel sulfate results in increased cleavage of PARP1 protein19135467
C029938nickel sulfatePARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]20493934
C029938nickel sulfatePotassium Dichromate inhibits the reaction [nickel sulfate results in increased cleavage of and results in increased activity of PARP1 protein]20493934
C029938nickel sulfatenickel sulfate results in increased cleavage of PARP1 protein19135467
D009534NiclosamideHydrogen Peroxide promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]24750999
D009534NiclosamideJUN protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]24750999
D009534NiclosamideNiclosamide results in decreased expression of PARP1 protein26917416
D009534NiclosamideNiclosamide results in increased cleavage of PARP1 protein24750999|2517439
D009534NiclosamideWNT7A protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]25174399
D009537Nicotinamide MononucleotidePARP1 protein affects the abundance of Nicotinamide Mononucleotide19426698
D009538NicotineNicotine inhibits the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form]22743290
D009538NicotineNicotine inhibits the reaction [Camptothecin results in increased cleavage of PARP1 protein]24095863
D009538NicotineNicotine inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]20457658
D009538NicotineNicotine inhibits the reaction [Fluorouracil results in increased cleavage of PARP1 protein]24095863
D009544Niflumic Acidbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]21067863
D009544Niflumic Acidbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]21067863
D009544Niflumic Acidciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]21067863
D009544Niflumic AcidDDIT3 mutant form inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]]21067863
D009544Niflumic AcidDDIT3 mutant form inhibits the reaction [Niflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]]21067863
D009544Niflumic AcidNiflumic Acid promotes the reaction [ciglitazone results in increased cleavage of PARP1 protein]21067863
D009544Niflumic AcidNiflumic Acid results in increased cleavage of PARP1 protein21067863
C012655nimesulidenimesulide results in increased cleavage of PARP1 protein19360361
C012655nimesulidenimesulide results in increased expression of PARP1 mRNA24136188
D009569Nitric OxideNitric Oxide results in increased cleavage of PARP1 protein15126337|1602461
D009569Nitric Oxide[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]10811113
D005996NitroglycerinNitroglycerin results in decreased expression of PARP1 protein alternative form17322376
D026423S-Nitroso-N-Acetylpenicillamine[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]10811113
C038405nivalenolnivalenol results in increased cleavage of PARP1 protein19410639
C562238N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide"N-methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4'-(trifluoromethyl)-(1,1'-biphenyl)-4-yl)-1H-pyrazol-3-yl)propanamide results in increased cleavage of PARP1 protein"21823616
C047330N-methylisoindigotin"(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]"26887594
C047330N-methylisoindigotinAcetylcysteine inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]26887594
C047330N-methylisoindigotinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]26887594
C047330N-methylisoindigotinGlutathione inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]26887594
C047330N-methylisoindigotinN-methylisoindigotin results in increased cleavage of PARP1 protein26887594
C542681N,N-dimethylphytosphingosine"benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [N,N-dimethylphytosphingosine results in increased cleavage of PARP1 protein]"19481559
C542681N,N-dimethylphytosphingosine"N,N-dimethylphytosphingosine results in increased cleavage of PARP1 protein"19481559
C061800N,N-dimethylsphingosine"[Bortezomib co-treated with N,N-dimethylsphingosine] results in increased cleavage of PARP1 protein"21195056
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]"15966574
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to PARP1 protein]"24275069
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PARP1 protein"24275069
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]"22253048
D015739NocodazoleNocodazole analog results in increased cleavage of PARP1 protein28412508
D015739NocodazoleNocodazole results in increased cleavage of PARP1 protein15907805|2190359
D015739NocodazoleTYMP inhibits the reaction [Nocodazole results in increased cleavage of PARP1 protein]15907805
C010615Nonidet P-40Nonidet P-40 results in decreased expression of PARP1 mRNA26552463
D009665NoscapineNoscapine results in increased cleavage of PARP1 protein22848370
C072936notoginsenoside R1notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein modified form]23170834
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]"18509044
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride results in decreased activity of PARP1 protein"11861791
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in increased activity of PARP1 protein]"24231740
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [NAD results in increased activity of PARP1 protein]"25440059
C434926N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride results in decreased activity of PARP1 protein"15710350|1788499
C514334NSC606985NSC606985 results in increased cleavage of PARP1 protein19747914
C122062NSC 674495PARP1 protein affects the susceptibility to NSC 67449517674193
C404397NSC 680410NSC 680410 results in increased degradation of PARP1 protein14647418
C404397NSC 680410NSC 680410 results in increased cleavage of PARP1 protein16481037
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of PARP1 mRNA20971185
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased cleavage of PARP1 protein20971185
C558013NSC 689534NSC 689534 results in increased cleavage of PARP1 protein20971185
D009706Nucleic Acids, Nucleotides, and Nucleosides"Poly Adenosine Diphosphate Ribose inhibits the reaction [PARP1 protein binds to Nucleic Acids, Nucleotides, and Nucleosides]"27694308
C482205nutlin 3nutlin 3 results in increased cleavage of PARP1 protein22260869
C482205nutlin 3TP53 mutant form inhibits the reaction [nutlin 3 results in increased cleavage of PARP1 protein]22260869
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"ATF3 mutant form inhibits the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in increased cleavage of PARP1 protein]"22003962
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"Buthionine Sulfoximine promotes the reaction [O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate affects the cleavage of PARP1 protein]"20962031
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate affects the cleavage of PARP1 protein"20962031
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate analog results in increased cleavage of PARP1 protein"22003962
C474958O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate"O(2)-(2,4-dinitrophenyl) 1-((4-ethoxycarbonyl)piperazin-1-yl)diazen-1-ium-1,2-diolate results in increased cleavage of PARP1 protein"20962031|2200396
C025589ochratoxin Aochratoxin A results in increased cleavage of PARP1 protein25002221
D019301Oleic AcidOleic Acid results in increased cleavage of PARP1 protein21132278
D016627OxidopamineOxidopamine results in increased cleavage of PARP1 protein25446857
D016627Oxidopaminepyrazolanthrone inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
D016627Oxidopaminesalvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
D016627OxidopamineSB 203580 inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
D016627OxidopamineTH protein inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]19815691
D016627OxidopamineOxidopamine results in increased cleavage of PARP1 protein10397638
D016627Oxidopamine"5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [Oxidopamine results in increased activity of PARP1 protein]"21397656
D016627OxidopamineOxidopamine results in increased activity of PARP1 protein21397656
D016627OxidopamineOxidopamine results in increased cleavage of PARP1 protein25446857
D016627Oxidopaminesalvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
D019319Okadaic AcidOkadaic Acid inhibits the reaction [Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]16059913
C531550olaparibolaparib inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]24814482
C531550olaparibolaparib results in decreased activity of PARP1 protein21417348
C013168olaquindoxCDKN1A protein affects the reaction [olaquindox results in increased cleavage of PARP1 protein]28757460
C013168olaquindoxolaquindox results in increased cleavage of PARP1 protein21549799|2875746
D009828Oleanolic AcidOleanolic Acid analog results in increased cleavage of PARP1 protein26612655
D009842Oligopeptides2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
D009842Oligopeptides3-methyladenine inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
D009842OligopeptidesAcetylcysteine inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
D009842OligopeptidesBECN1 mutant form inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
D009842Oligopeptidesbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]24875536
D009842OligopeptidesOligopeptides analog results in increased cleavage of PARP1 protein24875536
D009853OmeprazoleOmeprazole results in increased cleavage of PARP1 protein15461867
C507134ON 01910Imatinib Mesylate promotes the reaction [ON 01910 results in increased cleavage of PARP1 protein]26008977
C507134ON 01910ON 01910 promotes the reaction [Imatinib Mesylate results in increased cleavage of PARP1 protein]26008977
C507134ON 01910ON 01910 results in increased cleavage of PARP1 protein19198627|2181242
C000594117ON123300ON123300 results in increased cleavage of PARP1 protein26174628
C016340o,p'-DDT"o,p'-DDT affects the expression of PARP1 mRNA"17984292
D050607Organogold CompoundsOrganogold Compounds inhibits the reaction [Zinc binds to PARP1 protein]21370912
D050607Organogold CompoundsOrganogold Compounds promotes the reaction [Gold binds to PARP1 protein]21370912
D050607Organogold CompoundsOrganogold Compounds results in decreased activity of PARP1 protein21370912
D009942Organometallic CompoundsOrganometallic Compounds results in increased cleavage of PARP1 protein24905917
D016566Organoselenium CompoundsOrganoselenium Compounds results in increased cleavage of PARP1 protein24905917
C011959oridoninoridonin results in increased cleavage of PARP1 protein16019488
C055122orlistat[orlistat co-treated with Thapsigargin] results in increased cleavage of PARP1 protein17283163
C055122orlistatorlistat results in increased cleavage of PARP1 protein15870086|1728316
C000603933osimertinibAcetylcysteine inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]28237877
C000603933osimertinibCAT protein inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]28237877
C000603933osimertinibosimertinib results in increased expression of PARP1 protein modified form28237877
C000603933osimertinibVitamin E inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]28237877
C106408OSW 1OSW 1 analog results in increased cleavage of PARP1 protein21438635
C106408OSW 1OSW 1 analog results in increased expression of PARP1 protein21438635
C000605331OTX015OTX015 affects the cleavage of PARP1 protein26051217
C030110oxaliplatingefitinib affects the reaction [oxaliplatin results in increased cleavage of PARP1 protein]16243822
C030110oxaliplatin[oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased cleavage of PARP1 protein19728331
C030110oxaliplatinoxaliplatin results in increased cleavage of PARP1 protein16243822
C030110oxaliplatin[S100A11 mutant form results in increased susceptibility to oxaliplatin] which results in increased cleavage of PARP1 protein25940438
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of PARP1 mRNA25729387
C015407oxalomalic acidoxalomalic acid promotes the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]16785314
C015407oxalomalic acidoxalomalic acid promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]16785314
C552952oxazolinodaunorubicinoxazolinodaunorubicin affects the expression of PARP1 mRNA27780733
C029341oxophenylarsineoxophenylarsine results in increased cleavage of PARP1 protein10515888
D010100OxygenAHR mutant form promotes the reaction [Oxygen results in increased cleavage of PARP1 protein]25831079
D010100Oxygenbetulin analog promotes the reaction [Oxygen deficiency results in increased expression of PARP1 protein modified form]26540049
D010100Oxygen"N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide promotes the reaction [Oxygen deficiency results in increased cleavage of PARP1 protein]"20530905
D010100OxygenOxygen deficiency inhibits the reaction [nickel monoxide analog results in increased cleavage of PARP1 protein]27270449
D010100OxygenOxygen deficiency results in increased cleavage of PARP1 protein20530905
D010100OxygenOxygen deficiency results in increased expression of PARP1 protein modified form26540049
D010100OxygenOxygen results in increased cleavage of PARP1 protein25831079
D010100OxygenOxygen deficiency results in increased cleavage of PARP1 protein11042672
D010100OxygenPhenylephrine inhibits the reaction [Oxygen deficiency results in increased cleavage of PARP1 protein]11042672
D017239Paclitaxel"[3,3'-diindolylmethane co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of PARP1 protein"16580691
D017239PaclitaxelAKT1 protein affects the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10075725
D017239Paclitaxelalvocidib promotes the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10430095
D017239PaclitaxelCD40LG protein inhibits the reaction [Paclitaxel promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]16545138
D017239Paclitaxel[Luteolin co-treated with Paclitaxel] results in decreased expression of PARP1 protein24525192
D017239PaclitaxelMAP2K4 protein affects the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10075725
D017239PaclitaxelMAP3K5 protein affects the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10075725
D017239PaclitaxelMAPK8 protein affects the reaction [Paclitaxel results in increased cleavage of PARP1 protein]10075725
D017239PaclitaxelPaclitaxel promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]16545138
D017239PaclitaxelPaclitaxel results in increased cleavage of PARP1 protein10075725|1043009
D017239Paclitaxel[resveratrol co-treated with Paclitaxel] results in increased cleavage of PARP1 protein14749477
D017239PaclitaxelTYMP inhibits the reaction [Paclitaxel results in increased cleavage of PARP1 protein]15907805
D017239PaclitaxelTYMP mutant form promotes the reaction [Paclitaxel results in increased cleavage of PARP1 protein]15492279
C013638paeonolpaeonol inhibits the reaction [Epirubicin results in increased cleavage of PARP1 protein]26646421
C500026palbociclibpalbociclib inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]22751436
C500026palbociclib[palbociclib results in increased susceptibility to idelalisib] which results in increased cleavage of PARP1 protein23676220
C500026palbociclibRB1 protein affects the reaction [palbociclib inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]22751436
D010168PalmitatesGW 3965 inhibits the reaction [Palmitates results in increased cleavage of PARP1 protein]21209018
D010168PalmitatesPalmitates results in increased cleavage of PARP1 protein21209018
D010168PalmitatesPalmitates results in increased expression of PARP1 protein modified form21209018
D010168PalmitatesSREBF1 protein affects the reaction [Palmitates results in increased cleavage of PARP1 protein]21209018
D010168PalmitatesTO-901317 inhibits the reaction [Palmitates results in increased cleavage of PARP1 protein]21209018
C019248pamidronatepamidronate results in increased cleavage of PARP1 protein10780527|1534605
C019248pamidronate[pamidronate co-treated with ultra-high molecular weight polyethylene] results in increased cleavage of PARP1 protein12507583
C482884panduratin Apanduratin A results in increased cleavage of PARP1 protein16497706
C496932panobinostat[resveratrol co-treated with panobinostat] results in increased cleavage of PARP1 protein22923501
C016030pantogabpantogab results in decreased expression of PARP1 mRNA17379144
D010269Paraquat6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of PARP1 protein modified form]28414160
D010269Paraquat[Antimycin A co-treated with Paraquat] results in increased cleavage of PARP1 protein16237197
D010269ParaquatParaquat results in increased activity of PARP1 protein24130211
D010269ParaquatParaquat results in increased cleavage of PARP1 protein17018646|1805670
D010269ParaquatParaquat results in increased expression of PARP1 protein modified form27003823|2841416
D010269ParaquatPTGDS mutant form promotes the reaction [Paraquat results in increased cleavage of PARP1 protein]22043816
D010269Paraquat[PTGDS protein results in decreased susceptibility to Paraquat] which results in decreased cleavage of PARP1 protein22043816
D010269Paraquat[pyridaben co-treated with Paraquat] results in increased cleavage of PARP1 protein16237197
D010269ParaquatParaquat results in increased cleavage of PARP1 protein21300143|2842813
D010269ParaquatPARK7 protein affects the reaction [Paraquat results in increased cleavage of PARP1 protein]21300143
D010269Paraquatcalpeptin inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
D010269ParaquatCyclosporine inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
D010269ParaquatDibucaine inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
D010269Paraquatdiphenyleneiodonium inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein]25947082
D010269ParaquatParaquat results in increased cleavage of PARP1 protein25947082
C022097partheninparthenin analog results in increased cleavage of PARP1 protein25196075
D052638Particulate MatterParticulate Matter results in increased cleavage of PARP1 protein27187980
D052638Particulate MatterParticulate Matter results in increased expression of PARP1 mRNA24216475
C000610380p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane"p-carboxymethylphenyl 1,1-bis(3'-indolyl)-1-(p-carboxymethylphenyl)methane results in increased cleavage of PARP1 protein"26035713
C115711PD 173074[arsenic trioxide co-treated with PD 173074] results in increased expression of PARP1 protein modified form27794399
C115711PD 173074[arsenic trioxide results in increased susceptibility to PD 173074] which results in increased expression of PARP1 protein modified form27794399
C115711PD 173074[PD 173074 results in increased susceptibility to arsenic trioxide] which results in increased expression of PARP1 protein modified form27794399
D010396PenicillaminePenicillamine results in increased cleavage of PARP1 protein22843330
D010416PentachlorophenolPentachlorophenol results in increased expression of PARP1 mRNA23892564
D004369Pentetic AcidPentetic Acid inhibits the reaction [pyrithione zinc results in increased activity of PARP1 protein]21424779
D010431PentoxifyllinePentoxifylline promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]20804743
D010431PentoxifyllinePentoxifylline results in increased cleavage of PARP1 protein18851957
C031375pepstatinpepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein]16850161
C076994perfluorooctane sulfonic acidMIR155 mRNA promotes the reaction [perfluorooctane sulfonic acid results in increased cleavage of PARP1 protein]26844784
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased cleavage of PARP1 protein26844784
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased cleavage of PARP1 protein26844784
C004282periodate-oxidized adenosine 5'-triphosphateperiodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]22253048
C539933pevonedistatpevonedistat results in increased cleavage of PARP1 protein24634471
C539933pevonedistatpevonedistat results in increased cleavage of and results in increased activity of PARP1 protein22110742
C539933pevonedistatTretinoin promotes the reaction [pevonedistat results in increased cleavage of and results in increased activity of PARP1 protein]22110742
D015232DinoprostoneDinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein]19289254
C031181phenanthrenephenanthrene results in increased cleavage of PARP1 protein21132278
C040601phenanthridonephenanthridone results in decreased activity of PARP1 protein12411406
C040601phenanthridonephenanthridone results in decreased activity of PARP1 protein14769338|1757905
C058305phenethyl isothiocyanateAcetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased cleavage of PARP1 protein]25246272
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased cleavage of PARP1 protein25246272
D010634PhenobarbitalPhenobarbital affects the expression of PARP1 mRNA19159669
D010634PhenobarbitalPhenobarbital results in increased expression of PARP1 mRNA19162173
D010656PhenylephrinePhenylephrine inhibits the reaction [Oxygen deficiency results in increased cleavage of PARP1 protein]11042672
C005435phenylmethylpyrazolonephenylmethylpyrazolone analog results in increased cleavage of PARP1 protein25684395
D010696PhloroglucinolPhloroglucinol results in decreased expression of PARP1 protein modified form20188716
D010696PhloroglucinolPhloroglucinol analog results in increased cleavage of PARP1 protein23178381
D010696PhloroglucinolPhloroglucinol metabolite results in increased cleavage of PARP1 protein22796323
C030090phosphoramide mustardphosphoramide mustard affects the expression of PARP1 mRNA25497287
C030090phosphoramide mustardphosphoramide mustard results in increased expression of PARP1 mRNA26708502
C030090phosphoramide mustardphosphoramide mustard results in increased expression of PARP1 protein25497287|2670850
D010833Phytic Acid"Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]"11217149
D010833Phytic AcidPhytic Acid inhibits the reaction [Smoke analog results in increased activity of PARP1 protein]11217149
D064209PhytochemicalsPhytochemicals results in increased cleavage of PARP1 protein22685690
C012491phytosphingosine"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]"17237268
C012491phytosphingosineAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]17237268
C012491phytosphingosine[arsenic trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein17237268
C012491phytosphingosine[arsenic trioxide co-treated with phytosphingosine] results in increased cleavage of PARP1 protein17237268
C012491phytosphingosinephytosphingosine results in increased activity of PARP1 protein15486061
C121565pifithrinpifithrin inhibits the reaction [[decitabine co-treated with Busulfan] results in increased cleavage of PARP1 protein]19732952
C121565pifithrinpifithrin inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
C121565pifithrinpifithrin inhibits the reaction [goniothalamin results in increased cleavage of PARP1 protein]21810437
C121565pifithrinpifithrin inhibits the reaction [silybin results in increased cleavage of PARP1 protein]16777994
C121565pifithrinpifithrin inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]20045437
C121565pifithrinpifithrin promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein]22226932
C121565pifithrinpifithrin promotes the reaction [Mustard Gas results in increased cleavage of PARP1 protein]25448276
C121565pifithrinpifithrin inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C121565pifithrinpifithrin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16687611
C006253pirinixic acidpirinixic acid results in increased expression of PARP1 mRNA18301758
C006253pirinixic acidpirinixic acid affects the expression of PARP1 protein16912651
C006253pirinixic acidpirinixic acid results in decreased expression of PARP1 mRNA16940010
D010936Plant Extracts[arsenic trioxide co-treated with Plant Extracts] results in increased cleavage of PARP1 protein26160715
D010936Plant ExtractsPlant Extracts results in decreased expression of PARP1 mRNA15465739
D010936Plant ExtractsPlant Extracts results in increased cleavage of PARP1 protein17619071|1793570
D010936Plant ExtractsPlant Extracts results in increased expression of and results in increased cleavage of PARP1 protein25770932
D010936Plant Extracts[Plant Extracts co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein25449198
D010936Plant Extracts[Plant Extracts co-treated with manganese chloride] affects the cleavage of PARP1 protein26064043
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dextran Sulfate results in increased cleavage of PARP1 protein]21989142
D028321Plant PreparationsPlant Preparations results in increased cleavage of PARP1 protein15369734
D028321Plant PreparationsPlant Preparations inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]24875324
D028321Plant PreparationsPlant Preparations results in increased expression of PARP1 mRNA24973489
D010984PlatinumCisplatin promotes the reaction [Platinum binds to PARP1 protein]21370912
D011034PodophyllotoxinPodophyllotoxin results in increased cleavage of PARP1 protein21916509
D011064Poly Adenosine Diphosphate Ribose[arsenite results in decreased activity of PARP1 protein] which results in decreased chemical synthesis of Poly Adenosine Diphosphate Ribose22387748
D011064Poly Adenosine Diphosphate RibosePARP1 protein mutant form affects the abundance of Poly Adenosine Diphosphate Ribose27694308
D011064Poly Adenosine Diphosphate RibosePARP1 protein mutant form promotes the reaction [Hydrogen Peroxide results in increased abundance of Poly Adenosine Diphosphate Ribose]27694308
D011064Poly Adenosine Diphosphate RibosePARP1 protein promotes the reaction [Camptothecin results in increased abundance of Poly Adenosine Diphosphate Ribose]27694308
D011064Poly Adenosine Diphosphate RibosePARP1 protein promotes the reaction [Hydrogen Peroxide results in increased abundance of Poly Adenosine Diphosphate Ribose]27694308
D011064Poly Adenosine Diphosphate RibosePARP1 protein results in increased chemical synthesis of Poly Adenosine Diphosphate Ribose22387748
D011064Poly Adenosine Diphosphate RibosePoly Adenosine Diphosphate Ribose binds to PARP1 protein27694308
D011064Poly Adenosine Diphosphate Ribose"Poly Adenosine Diphosphate Ribose inhibits the reaction [PARP1 protein binds to Nucleic Acids, Nucleotides, and Nucleosides]"27694308
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased cleavage of PARP1 protein21132278
C043435polylactic acid-polyglycolic acid copolymer[polylactic acid-polyglycolic acid copolymer co-treated with Apigenin] results in increased cleavage of PARP1 protein24070738
D059808PolyphenolsPolyphenols results in decreased expression of PARP1 mRNA15465739
C556217polyphyllin Ipolyphyllin I results in increased cleavage of PARP1 protein26821882
D011134PolysaccharidesPolysaccharides inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein]24875324
C545373ponatinib(+)-JQ1 compound promotes the reaction [ponatinib results in increased cleavage of PARP1 protein]25053825
C545373ponatinibponatinib promotes the reaction [(+)-JQ1 compound results in increased cleavage of PARP1 protein]25053825
C545373ponatinibponatinib results in increased cleavage of PARP1 protein21482694|2287561
C027373potassium chromate(VI)epigallocatechin gallate inhibits the reaction [potassium chromate(VI) results in increased cleavage of and results in increased activity of PARP1 protein]22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased cleavage of and results in increased activity of PARP1 protein22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased cleavage of PARP1 protein25977998
D011192Potassium Dichromate3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]]20493934
D011192Potassium Dichromatenickel sulfate inhibits the reaction [Potassium Dichromate results in increased cleavage of and results in increased activity of PARP1 protein]20493934
D011192Potassium DichromatePARP1 protein results in increased susceptibility to [Potassium Dichromate co-treated with nickel sulfate]20493934
D011192Potassium DichromatePotassium Dichromate inhibits the reaction [nickel sulfate results in increased cleavage of and results in increased activity of PARP1 protein]20493934
D011192Potassium DichromatePotassium Dichromate results in increased cleavage of and results in increased activity of PARP1 protein20493934
D011192Potassium DichromateAscorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of PARP1 protein]21262251
D011192Potassium DichromatePotassium Dichromate results in increased cleavage of PARP1 protein21262251
D011335Proadifen[Proadifen co-treated with Cisplatin] results in increased cleavage of PARP1 protein26721606
D011353ProdigiosinProdigiosin results in increased cleavage of PARP1 protein15746575|1913328
C066229prolinedithiocarbamate[prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein21035945
C066229prolinedithiocarbamateAcetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein]22909951
C066229prolinedithiocarbamate[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein22909951
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors results in increased cleavage of PARP1 protein21878655
C456319PS1145PS1145 inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]19616567
C107773pterostilbenepterostilbene results in increased expression of PARP1 protein modified form19549798
C033607puerarinpuerarin inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]27717697
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]23082001
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]16328441
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [dehydroxymethylepoxyquinomicin results in increased cleavage of PARP1 protein]15501958
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [docetaxel results in increased cleavage of PARP1 protein]14724571
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]16407847
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]25939952
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [LY 293111 results in increased cleavage of PARP1 protein]16151469
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]21165570
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19777565
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]18281123
C432165pyrazolanthronepyrazolanthrone promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
C432165pyrazolanthronepyrazolanthrone results in increased susceptibility to [[TNFSF10 protein co-treated with kahweol acetate] results in increased cleavage of PARP1 protein]20403343
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [3-dinitrobenzene results in increased cleavage of PARP1 protein]19477251
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [bakuchiol results in increased cleavage of PARP1 protein]17292878
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]24577723|2504395
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]23405080
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]21843586
C432165pyrazolanthrone"pyrazolanthrone inhibits the reaction [Asbestos, Serpentine results in increased expression of PARP1 protein]"25530474
C030984pyrenepyrene results in increased cleavage of PARP1 protein21132278
D011722PyrethrinsPyrethrins results in increased cleavage of PARP1 protein27939866
C428725pyridaben[pyridaben co-treated with Paraquat] results in increased cleavage of PARP1 protein16237197
C428725pyridabenpyridaben results in increased cleavage of PARP1 protein16237197
C077792pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid"pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]"22253048
C009131pyrimidin-2-one beta-ribofuranosidepyrimidin-2-one beta-ribofuranoside results in increased cleavage of PARP1 protein19459041
C010423pyrithione zincPentetic Acid inhibits the reaction [pyrithione zinc results in increased activity of PARP1 protein]21424779
C010423pyrithione zincpyrithione zinc results in increased activity of PARP1 protein21424779
C010423pyrithione zincPARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate]19809895
C010423pyrithione zincPARP1 protein affects the susceptibility to pyrithione zinc19809895
D011794Quercetin2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]14688022|2116557
D011794Quercetin[ABCB1 protein results in decreased susceptibility to Doxorubicin] inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]20438634
D011794QuercetinAKT1 protein inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]20386985
D011794Quercetin[BAX protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein18455702
D011794Quercetinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Quercetin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]20096292
D011794Quercetinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]14688022
D011794QuercetinDDIT3 protein affects the reaction [[TNFSF10 protein co-treated with Quercetin] results in increased cleavage of PARP1 protein]24612139
D011794Quercetin[ESR1 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein19194971
D011794Quercetin[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein21732360
D011794Quercetinfulvestrant inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]21732360
D011794QuercetinNFE2L2 protein inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]25896339
D011794Quercetinpyrazolanthrone inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]21165570
D011794Quercetin[Quercetin co-treated with hyperoside] results in increased cleavage of PARP1 protein24173369|2535454
D011794QuercetinQuercetin inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
D011794QuercetinQuercetin inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]22002103
D011794QuercetinQuercetin metabolite results in increased cleavage of PARP1 protein19138980
D011794QuercetinQuercetin metabolite results in increased expression of PARP1 protein16280456
D011794QuercetinQuercetin promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]25611565
D011794QuercetinQuercetin promotes the reaction [manumycin results in increased cleavage of PARP1 protein]14625852
D011794QuercetinQuercetin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]17548900|1787605
D011794QuercetinQuercetin results in decreased activity of PARP1 protein17884996
D011794QuercetinQuercetin results in decreased expression of PARP1 mRNA20596804
D011794QuercetinQuercetin results in increased cleavage of PARP1 protein12168845|1287483
D011794QuercetinQuercetin results in increased degradation of PARP1 protein16059641
D011794QuercetinQuercetin results in increased expression of PARP1 protein modified form19017364
D011794Quercetin[resveratrol co-treated with Quercetin] results in increased cleavage of PARP1 protein23530649
D011794QuercetinSB 203580 inhibits the reaction [[ESR1 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein]19194971
D011794QuercetinSB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein]21732360
D011794Quercetintauroursodeoxycholic acid inhibits the reaction [Quercetin promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]]25611565
D011794Quercetin[TNFSF10 protein co-treated with Quercetin] results in increased cleavage of PARP1 protein24612139
D011794QuercetinU 0126 inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]14688022
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased cleavage of PARP1 protein]"21294050
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]15876423
D011794QuercetinQuercetin results in decreased expression of PARP1 protein17039455
D011794QuercetinQuercetin results in increased cleavage of PARP1 protein26076811
D011794QuercetinQuercetin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]24902966
D011794QuercetinQuercetin inhibits the reaction [estradiol 3-benzoate results in increased cleavage of PARP1 protein]24316378
D011794QuercetinQuercetin inhibits the reaction [Glucose results in increased cleavage of PARP1 protein]22524206
D011794QuercetinQuercetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]14505808
D011794QuercetinQuercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]23138875
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [TNFSF10 protein results in increased expression of PARP1 protein modified form]23711929
C523166quercetin 3-O-beta-(2''-galloyl)-rhamnopyranosidequercetin 3-O-beta-(2''-galloyl)-rhamnopyranoside inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]25845326
C110310quercetin 4'-O-glucopyranoside[VEGFA protein co-treated with quercetin 4'-O-glucopyranoside analog] results in increased cleavage of PARP1 protein22348123
C012526quercitrinquercitrin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]23138875
D011796QuinacrineQuinacrine results in increased cleavage of PARP1 protein28867437
C502851quinocetone"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]"28343033
C502851quinocetoneLithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form]28343033
C502851quinocetonequinocetone results in increased expression of PARP1 protein modified form28343033
D011804QuinolinesQuinolines analog results in increased cleavage of PARP1 protein15826604
C468548quinoline-val-asp(OMe)-CH2-OPHquinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [epoxomicin results in increased cleavage of PARP1 protein]20153345
C544967quizartinib(+)-JQ1 compound promotes the reaction [quizartinib results in increased cleavage of PARP1 protein]25053825
C544967quizartinibquizartinib promotes the reaction [(+)-JQ1 compound results in increased cleavage of PARP1 protein]25053825
C544967quizartinibquizartinib results in increased cleavage of PARP1 protein25053825
D011899RanitidineRanitidine inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19723537
C534678RAPTA-TRAPTA-T inhibits the reaction [Zinc binds to PARP1 protein]21370912
C534678RAPTA-TRAPTA-T promotes the reaction [Ruthenium binds to PARP1 protein]21370912
C534678RAPTA-TRAPTA-T results in decreased activity of PARP1 protein21370912
D017382Reactive Oxygen Species"[2,3,5-(triglutathion-S-yl)hydroquinone results in increased abundance of Reactive Oxygen Species] which results in increased activity of PARP1 protein"24752504|2852562
D017382Reactive Oxygen Species[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]24100277
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in decreased expression of PARP1 mRNA25800948
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased cleavage of PARP1 protein16412576
C059514resveratrol"[2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid co-treated with methylselenic acid co-treated with resveratrol] results in increased cleavage of PARP1 protein"18444175
C059514resveratrol3-methyladenine inhibits the reaction [resveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]21778691
C059514resveratrolBCL2 protein inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]19631782
C059514resveratrolBECN1 protein affects the reaction [resveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]21778691
C059514resveratrolbenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C059514resveratrolbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C059514resveratrolCASP12 mutant form inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of PARP1 mRNA19167446
C059514resveratrolCycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C059514resveratrolMCL1 mutant form promotes the reaction [[resveratrol co-treated with clofarabine] results in increased cleavage of PARP1 protein]24924397
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased acetylation of and results in increased phosphorylation of TP53 protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of BRCA1 protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of CDKN2A protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of FOXO3 protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of NAMPT protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of SESN2 protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of SIRT1 protein]25533949
C059514resveratrolPARP1 protein affects the reaction [resveratrol results in increased expression of SIRT6 protein]25533949
C059514resveratrolresveratrol analog results in increased cleavage of PARP1 protein24044363
C059514resveratrol[resveratrol co-treated with clofarabine] results in increased cleavage of PARP1 protein24924397
C059514resveratrol[resveratrol co-treated with clofarabine] results in increased expression of PARP1 protein modified form24239893
C059514resveratrol[resveratrol co-treated with Paclitaxel] results in increased cleavage of PARP1 protein14749477
C059514resveratrol[resveratrol co-treated with panobinostat] results in increased cleavage of PARP1 protein22923501
C059514resveratrol[resveratrol co-treated with Quercetin] results in increased cleavage of PARP1 protein23530649
C059514resveratrolresveratrol inhibits the reaction [Dopamine results in increased cleavage of PARP1 protein]17603292
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of PARP1 protein modified form]24218232
C059514resveratrolresveratrol inhibits the reaction [IL1B protein results in increased cleavage of PARP1 protein]17404069|1795915
C059514resveratrolresveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]21778691
C059514resveratrolresveratrol promotes the reaction [Erlotinib Hydrochloride results in increased expression of PARP1 protein modified form]25895606
C059514resveratrolresveratrol promotes the reaction [PARP1 protein binds to YARS protein]25533949
C059514resveratrol[resveratrol promotes the reaction [PARP1 protein binds to YARS protein]] which results in increased ADP-ribosylation of PARP1 protein25533949
C059514resveratrolresveratrol promotes the reaction [sorafenib results in increased cleavage of PARP1 protein]26911335
C059514resveratrolresveratrol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]17823925
C059514resveratrol[resveratrol results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein19561642
C059514resveratrol[resveratrol results in increased activity of SIRT1 protein] which results in decreased activity of PARP1 protein16628003
C059514resveratrolresveratrol results in increased ADP-ribosylation of PARP1 protein25533949
C059514resveratrolresveratrol results in increased cleavage of PARP1 protein12690110|1661705
C059514resveratrolresveratrol results in increased degradation of PARP1 protein20028382
C059514resveratrolresveratrol results in increased expression of PARP1 protein modified form9680369
C059514resveratrolthermozymocidin inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C059514resveratrol[vorinostat co-treated with resveratrol] results in increased cleavage of PARP1 protein22923501
C059514resveratrolvorinostat inhibits the reaction [BCL2 protein inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]]19631782
C059514resveratrolYARS protein affects the reaction [resveratrol results in increased ADP-ribosylation of PARP1 protein]25533949
C059514resveratrol"1-(4-dimethylaminomethylphenyl)-8,9-dihydro-7H-2,7,9a-benzo(cd)azulen-6-one inhibits the reaction [resveratrol promotes the reaction [PARP1 protein binds to YARS protein]]"25533949
C059514resveratrolresveratrol inhibits the reaction [PPT1 gene mutant form results in increased expression of PARP1 protein modified form]21224254
C059514resveratrolresveratrol inhibits the reaction [Sodium Fluoride results in increased cleavage of PARP1 protein]24296261
C059514resveratrolresveratrol promotes the reaction [PARP1 protein binds to YARS protein]25533949
C059514resveratrolresveratrol results in increased ADP-ribosylation of PARP1 protein25533949
C059514resveratrolresveratrol results in increased cleavage of PARP1 protein16675471|1787296
C059514resveratrolresveratrol inhibits the reaction [Estradiol results in decreased cleavage of PARP1 protein]24894866
C059514resveratrolresveratrol inhibits the reaction [Excitatory Amino Acid Agonists results in increased cleavage of PARP1 protein]24675465
C059514resveratrolresveratrol inhibits the reaction [Testosterone results in increased expression of PARP1 protein]25714330
C059514resveratrolresveratrol results in decreased cleavage of PARP1 protein24675465
C059514resveratrolresveratrol results in increased cleavage of PARP1 protein24304514|2489486
C059514resveratrol[Sirolimus co-treated with resveratrol] results in increased cleavage of PARP1 protein24304514
C059514resveratrolTSC2 protein inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24304514
C059514resveratrolTSC2 protein inhibits the reaction [[Sirolimus co-treated with resveratrol] results in increased cleavage of PARP1 protein]24304514
C540615retigeric acid Bretigeric acid B results in increased cleavage of PARP1 protein20692244
D012172RetinaldehydeRetinaldehyde results in increased cleavage of PARP1 protein25331497
C547185riccardin Driccardin D results in increased cleavage of PARP1 protein24069304
C547185riccardin Driccardin D results in increased cleavage of PARP1 protein24069304
C089032rimonabantrimonabant results in decreased expression of PARP1 protein19479993
D019438RitonavirRitonavir results in increased cleavage of PARP1 protein19386116|2127066
C071721Ro 41-0960Ro 41-0960 results in decreased expression of PARP1 protein21896544
C087123romidepsinBortezomib promotes the reaction [romidepsin results in increased cleavage of PARP1 protein]18223231
C087123romidepsinromidepsin results in increased cleavage of PARP1 protein18223231
C037663ropivacaineBCL2 protein inhibits the reaction [ropivacaine results in increased cleavage of PARP1 protein]15538973
C037663ropivacaineCLU protein inhibits the reaction [ropivacaine results in increased cleavage of PARP1 protein]15538973
C037663ropivacaineropivacaine results in increased cleavage of PARP1 protein15538973
C104586roscovitineroscovitine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]18501396
D012402Rotenone3-methyladenine inhibits the reaction [resveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]21778691
D012402Rotenoneaspartyl-glutamyl-valyl-aspartal inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]14976342
D012402RotenoneATG5 protein affects the reaction [Sirolimus inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]19682553
D012402RotenoneBECN1 protein affects the reaction [resveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]21778691
D012402Rotenonepyrazolanthrone inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19777565
D012402RotenoneRanitidine inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19723537
D012402Rotenoneresveratrol inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]21778691
D012402RotenoneRotenone results in increased cleavage of PARP1 protein14976342|1953900
D012402RotenoneSB 203580 inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19777565
D012402RotenoneSirolimus inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19682553
D012402RotenoneTranexamic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19539006
D012402RotenoneRotenone results in increased cleavage of PARP1 protein19857556
D012402RotenoneSNCAIP protein inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19857556
D012402RotenoneCAT protein inhibits the reaction [[Rotenone results in increased abundance of Hydrogen Peroxide] which results in increased cleavage of PARP1 protein]25304210
D012402RotenoneEllagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]25247703
D012402Rotenone[Rotenone results in increased abundance of Hydrogen Peroxide] which results in increased cleavage of PARP1 protein25304210
D012402RotenoneRotenone results in increased cleavage of PARP1 protein25247703
C085746rottlerinrottlerin results in increased cleavage of PARP1 protein22902833
C085746rottlerinrottlerin inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
C046245rubimaillinBCL2L1 protein inhibits the reaction [rubimaillin results in increased degradation of PARP1 protein]19716835
C046245rubimaillinbenzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [rubimaillin results in increased degradation of PARP1 protein]19716835
C046245rubimaillinrubimaillin results in increased degradation of PARP1 protein19716835
D012428Rutheniumimidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III) promotes the reaction [Ruthenium binds to PARP1 protein]21370912
D012428RutheniumRAPTA-T promotes the reaction [Ruthenium binds to PARP1 protein]21370912
C039961S-(1,2-dichlorovinyl)cysteine"S-(1,2-dichlorovinyl)cysteine results in increased cleavage of PARP1 protein"15967204
C571832saccharic acid-1,4-lactone"saccharic acid-1,4-lactone inhibits the reaction [Alloxan results in increased degradation of PARP1 protein]"21982801
C000687salicyl hydrazidesalicyl hydrazide analog results in increased cleavage of PARP1 protein25684395
C496827salubrinalsalubrinal inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21809093
C496827salubrinalsalubrinal inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
C066201salvianolic acid Asalvianolic acid A inhibits the reaction [arsenic trioxide results in increased expression of PARP1 protein]28391263
C018381salvinAcetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein]28918123
C018381salvinsalvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
C018381salvinsalvin results in decreased expression of PARP1 protein28918123
C018381salvinsalvin results in increased cleavage of PARP1 protein28918123
C018381salvinsalvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
D012503SaponinsSaponins results in increased cleavage of PARP1 protein28088315
C014184satratoxin Hsatratoxin H results in increased cleavage of PARP1 protein22863859
C410958sauchinonesauchinone results in increased cleavage of PARP1 protein27871897
C093642SB 203580"SB 203580 inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]"24036456
C093642SB 203580SB 203580 inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]16328441
C093642SB 203580SB 203580 inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]16843435
C093642SB 203580SB 203580 inhibits the reaction [Emodin results in increased cleavage of PARP1 protein]27032576
C093642SB 203580SB 203580 inhibits the reaction [[ESR1 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein]19194971
C093642SB 203580SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein]21732360
C093642SB 203580SB 203580 inhibits the reaction [[ESR2 protein results in increased susceptibility to Quercetin] which results in increased cleavage of PARP1 protein]21732360
C093642SB 203580SB 203580 inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein]25446857
C093642SB 203580SB 203580 inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19777565
C093642SB 203580SB 203580 inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]14645110
C417521SB 216763SB 216763 inhibits the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
C417521SB 216763SB 216763 inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]17849503
C417521SB 216763SB 216763 promotes the reaction [cinobufagin results in increased expression of PARP1 protein modified form]23164673
C417521SB 216763SB 216763 inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]24560772
C417521SB 216763SB 216763 inhibits the reaction [Excitatory Amino Acid Agonists results in increased cleavage of PARP1 protein]24675465
C417521SB 216763SB 216763 promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]27658547
C499748SCIO-469SCIO-469 promotes the reaction [Bortezomib results in increased cleavage of PARP1 protein]16617327
D012604Scorpion VenomsScorpion Venoms results in increased cleavage of PARP1 protein19913524
C524947Scutellaria barbata extractScutellaria barbata extract results in increased cleavage of PARP1 protein15369734
C552033S-dimethylaminoarsino-thiosuccinic acidS-dimethylaminoarsino-thiosuccinic acid analog results in increased cleavage of PARP1 protein19468689
D012642SelegilineSelegiline inhibits the reaction [linsidomine results in decreased expression of PARP1 protein]12880480
D012643SeleniumAKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]17339365
D012643SeleniumBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]17339365
D012643Selenium[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein17339365
C002979selenomethylselenocysteine[Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form25321483
C002979selenomethylselenocysteineBMF protein promotes the reaction [selenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form]25321483
C002979selenomethylselenocysteineselenomethylselenocysteine metabolite results in increased expression of PARP1 protein modified form25321483
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of PARP1 mRNA"25530474
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of PARP1 protein"25530474
D017632Asbestos, Serpentine"pyrazolanthrone inhibits the reaction [Asbestos, Serpentine results in increased expression of PARP1 protein]"25530474
C054125sesaminsesamin inhibits the reaction [Glucose results in increased cleavage of PARP1 protein]22524206
D012717SesquiterpenesSesquiterpenes results in increased cleavage of PARP1 protein18070620
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
C042431S-ethyl glutathioneS-ethyl glutathione inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
C016101shikoninAcetylcysteine inhibits the reaction [shikonin results in increased cleavage of PARP1 protein]24463199
C016101shikoninshikonin results in increased cleavage of PARP1 protein24463199
C040115shogaolAcetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
C040115shogaolAcetylcysteine inhibits the reaction [shogaol results in increased cleavage of PARP1 protein]18384088
C040115shogaolbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
C040115shogaolCFLAR protein modified form inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
C040115shogaolS-ethyl glutathione inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]25619640
C040115shogaolshogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]25619640
C040115shogaolshogaol results in increased cleavage of PARP1 protein18384088|2561964
D012822Silicon Dioxidedecitabine inhibits the reaction [Silicon Dioxide results in decreased expression of PARP1 mRNA]20123007
D012822Silicon DioxideDNMT1 protein promotes the reaction [Silicon Dioxide results in increased methylation of PARP1 promoter]22265868
D012822Silicon DioxidePARP1 protein inhibits the reaction [Silicon Dioxide results in increased expression of H2AFX protein modified form]28757444
D012822Silicon DioxidePARP1 protein results in decreased susceptibility to Silicon Dioxide28757444
D012822Silicon DioxideSilicon Dioxide results in decreased expression of PARP1 mRNA20123007|2226586
D012822Silicon DioxideSilicon Dioxide results in decreased expression of PARP1 protein22265868
D012822Silicon DioxideSilicon Dioxide results in increased cleavage of PARP1 protein19783790
D012822Silicon DioxideSilicon Dioxide results in increased methylation of PARP1 promoter22265868
C440975silybinbenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [silybin results in increased cleavage of PARP1 protein]24440808
C440975silybinGDF15 mutant form inhibits the reaction [silybin results in increased cleavage of PARP1 protein]24440808
C440975silybinpifithrin inhibits the reaction [silybin results in increased cleavage of PARP1 protein]16777994
C440975silybinsilybin results in increased cleavage of and results in increased activity of PARP1 protein16777994
C440975silybinsilybin results in increased cleavage of PARP1 protein24440808
D012838SilymarinSilymarin results in increased cleavage of PARP1 protein19168119
D012838SilymarinSilymarin inhibits the reaction [Doxorubicin results in increased expression of PARP1 protein]20144634
D012838SilymarinSilymarin results in decreased expression of PARP1 protein20144634
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]21910007
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]21910007
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]21910007
D019821SimvastatinMevalonic Acid inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]20045437
D019821SimvastatinMevalonic Acid inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]]21910007
D019821Simvastatinpifithrin inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]20045437
D019821Simvastatin[Simvastatin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein21910007
D019821SimvastatinSimvastatin inhibits the reaction [Coal Ash results in increased expression of PARP1 protein modified form]26773838
D019821SimvastatinSimvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]21910007
D019821SimvastatinSimvastatin results in increased cleavage of PARP1 protein20045437|2046444
D019821SimvastatinTNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]21910007
D019821SimvastatinIGF1 protein inhibits the reaction [Simvastatin results in increased cleavage of PARP1 protein]27734117
D019821SimvastatinSimvastatin results in increased cleavage of PARP1 protein27734117
D019821SimvastatinSimvastatin inhibits the reaction [Glucose results in increased activity of PARP1 protein]18004065
D019821SimvastatinSimvastatin results in decreased cleavage of PARP1 mRNA16054375
C574383sinularinAcetylcysteine inhibits the reaction [sinularin results in increased cleavage of PARP1 protein]28548367
C574383sinularinsinularin results in increased cleavage of PARP1 protein28548367
D020123SirolimusATG5 protein affects the reaction [Sirolimus inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]19682553
D020123SirolimusSirolimus inhibits the reaction [Ethanol results in increased cleavage of PARP1 protein]21410490
D020123SirolimusSirolimus inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19682553
D020123SirolimusSirolimus results in increased cleavage of PARP1 protein25307878
D020123SirolimusSirolimus promotes the reaction [Cadmium results in increased cleavage of PARP1 protein]29111403
D020123Sirolimus[Sirolimus co-treated with resveratrol] results in increased cleavage of PARP1 protein24304514
D020123SirolimusSirolimus results in increased expression of PARP1 protein modified form26825372
D020123SirolimusTSC2 protein inhibits the reaction [[Sirolimus co-treated with resveratrol] results in increased cleavage of PARP1 protein]24304514
C000619853SM-1 compound[SM-1 compound co-treated with Fluorouracil] results in increased expression of PARP1 protein28599477
C000619853SM-1 compoundSM-1 compound promotes the reaction [Fluorouracil results in increased expression of PARP1 mRNA]28599477
C000619853SM-1 compoundSM-1 compound results in increased expression of PARP1 mRNA28599477
D012906Smoke3-aminobenzamide inhibits the reaction [Smoke analog results in increased activity of PARP1 protein]11217149
D012906SmokeCAT protein inhibits the reaction [Smoke analog results in increased activity of PARP1 protein]11217149
D012906SmokePhytic Acid inhibits the reaction [Smoke analog results in increased activity of PARP1 protein]11217149
D012906Smoke"[Smoke analog co-treated with Asbestos, Amosite] results in increased activity of PARP1 protein"11217149
D012906SmokeSmoke analog results in increased activity of PARP1 protein11217149
C534922SNX 2112SNX 2112 results in increased cleavage of PARP1 protein23777986
C017947sodium arsenite[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]24100277
C017947sodium arseniteAcetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]19536524
C017947sodium arsenitebenzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]21642427
C017947sodium arsenitebenzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]21642427
C017947sodium arseniteBLVRA protein inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]15741166
C017947sodium arseniteCurcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]23710286
C017947sodium arseniteHMOX1 mutant form promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]21910007
C017947sodium arseniteLithium inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]17849503
C017947sodium arseniteroscovitine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]18501396
C017947sodium arseniteSB 216763 inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]17849503
C017947sodium arsenitesodium arsenite binds to and affects the folding of PARP1 protein24275069
C017947sodium arsenitesodium arsenite binds to and results in decreased activity of PARP1 protein28552776
C017947sodium arsenite[sodium arsenite co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in increased cleavage of PARP1 protein15028728
C017947sodium arsenite[sodium arsenite co-treated with FASLG protein] results in increased cleavage of PARP1 protein18977016
C017947sodium arsenite[sodium arsenite co-treated with Hydrogen Peroxide] results in increased cleavage of PARP1 protein18977016
C017947sodium arsenite[sodium arsenite co-treated with Vitamin K 3] results in increased cleavage of PARP1 protein19082730
C017947sodium arsenitesodium arsenite inhibits the reaction [Zinc binds to PARP1 protein]24275069|2855277
C017947sodium arsenitesodium arsenite results in decreased activity of PARP1 protein19056730|2003627
C017947sodium arsenitesodium arsenite results in increased cleavage of PARP1 protein15028728|1574116
C017947sodium arsenitesodium arsenite results in increased degradation of PARP1 protein12614848
C017947sodium arsenitesodium arsenite results in increased expression of PARP1 mRNA28595984
C017947sodium arsenitesodium arsenite results in increased expression of PARP1 protein20036271
C017947sodium arsenitetetramethylpyrazine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]26404762
C017947sodium arseniteTP53 protein inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]16614167
C017947sodium arsenitewortmannin promotes the reaction [sodium arsenite results in increased degradation of PARP1 protein]12614848
C017947sodium arseniteXIAP protein inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]22627131
C017947sodium arsenitezinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]19056730
C017947sodium arseniteZinc inhibits the reaction [sodium arsenite inhibits the reaction [Zinc binds to PARP1 protein]]24275069
C017947sodium arseniteZinc inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]24275069|2855277
C017947sodium arsenitebenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C017947sodium arsenitebetadex inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C017947sodium arseniteCDKN1B protein affects the reaction [sodium arsenite results in increased cleavage of PARP1 protein]20566634
C017947sodium arseniteCurcumin inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C017947sodium arseniteDithiothreitol inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C017947sodium arseniteGADD45A protein promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]16973625
C017947sodium arseniteMAPK8 protein promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]16973625
C017947sodium arseniteMAPK9 protein promotes the reaction [sodium arsenite results in increased cleavage of PARP1 protein]16973625
C017947sodium arseniteNFE2L1 protein alternative form inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]28549828
C017947sodium arsenitePARP1 gene mutant form results in increased susceptibility to sodium arsenite16322246
C017947sodium arsenitesodium arsenite promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]23143138
C017947sodium arsenitesodium arsenite results in decreased activity of PARP1 protein26443841
C017947sodium arsenitesodium arsenite results in increased cleavage of PARP1 protein11035063|1697362
C017947sodium arsenitesodium arsenite results in increased expression of PARP1 mRNA20643705
C017947sodium arsenitesodium arsenite results in increased expression of PARP1 protein modified form23143138
C017947sodium arseniteStaurosporine affects the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
C017947sodium arseniteZinc inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]26443841
C017947sodium arsenitePS1145 inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]19616567
C017947sodium arsenitesodium arsenite results in increased cleavage of PARP1 protein19616567
C017947sodium arsenitesodium arsenite results in increased degradation of PARP1 protein20830294
C017947sodium arseniteTaurine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]19616567
C017947sodium arseniteTaurine inhibits the reaction [sodium arsenite results in increased degradation of PARP1 protein]20830294
C016104sodium bichromateFBP1 protein promotes the reaction [sodium bichromate results in increased cleavage of PARP1 protein]28624442
C016104sodium bichromatesodium bichromate results in increased cleavage of PARP1 protein28624442
C016104sodium bichromateCAT protein inhibits the reaction [sodium bichromate results in increased cleavage of PARP1 protein]20298709
C016104sodium bichromatesodium bichromate results in increased cleavage of PARP1 protein20298709
C016104sodium bichromatesodium bichromate results in increased expression of PARP1 mRNA22155349
C016104sodium bichromateTRP53 mutant form inhibits the reaction [sodium bichromate results in increased cleavage of PARP1 protein]20298709
C016104sodium bichromatesodium bichromate affects the expression of PARP1 mRNA11960910
C025451sodium bisulfidesodium bisulfide results in increased cleavage of and results in increased activity of PARP1 protein23479079
D012969Sodium Fluorideresveratrol inhibits the reaction [Sodium Fluoride results in increased cleavage of PARP1 protein]24296261
D012969Sodium FluorideSodium Fluoride results in increased cleavage of PARP1 protein24296261
D012980Sodium SalicylateSodium Salicylate inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]29117515
D012980Sodium SalicylateSodium Salicylate promotes the reaction [Metformin results in increased expression of PARP1 mRNA]29117515
D012980Sodium SalicylateSodium Salicylate results in increased cleavage of PARP1 protein10090950|9694730
D012980Sodium SalicylateSodium Salicylate results in increased expression of PARP1 mRNA29117515
D018038Sodium SeleniteSodium Selenite results in increased cleavage of PARP1 protein15845651|2816141
D018038Sodium SeleniteSodium Selenite results in increased expression of PARP1 mRNA18175754
D018038Sodium SeleniteSodium Selenite results in decreased activity of PARP1 protein18209489
D012999SomanSoman results in decreased expression of PARP1 mRNA19281266
C471405sorafenibAKT1 protein inhibits the reaction [[Bortezomib co-treated with sorafenib] results in increased cleavage of PARP1 protein]16985072
C471405sorafenib[Bortezomib co-treated with sorafenib] results in increased cleavage of PARP1 protein16985072
C471405sorafenibresveratrol promotes the reaction [sorafenib results in increased cleavage of PARP1 protein]26911335
C471405sorafenib[sorafenib co-treated with PRKN protein] results in increased cleavage of PARP1 protein28673964
C471405sorafenibsorafenib results in increased cleavage of PARP1 protein20054642|2691133
C091861spermine nitric oxide complexspermine nitric oxide complex results in increased cleavage of PARP1 protein16024610
D013141Spiro CompoundsSpiro Compounds analog results in decreased cleavage of PARP1 protein25320076
C518872SRM 1597SRM 1597 results in increased cleavage of PARP1 protein21132278
D019311StaurosporineEOMES protein inhibits the reaction [Staurosporine results in increased cleavage of PARP1 protein]27539959
D019311StaurosporineStaurosporine results in increased cleavage of PARP1 protein18451153|2144780
D019311StaurosporineSOD2 mutant form inhibits the reaction [Staurosporine results in increased cleavage of PARP1 protein]24740755
D019311StaurosporineStaurosporine affects the reaction [sodium arsenite results in increased cleavage of PARP1 protein]11035063
D019311StaurosporineStaurosporine results in increased cleavage of PARP1 protein10704466|1103506
C049985staurosporine aglyconestaurosporine aglycone inhibits the reaction [NOG protein inhibits the reaction [Arsenic results in increased cleavage of PARP1 protein]]28903487
D013311StreptozocinCurcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]25541178
D013311StreptozocinStreptozocin results in increased cleavage of PARP1 protein25541178
D010042OuabainMitomycin promotes the reaction [Ouabain results in increased cleavage of PARP1 protein]24124520
D010042OuabainOuabain promotes the reaction [Mitomycin results in increased cleavage of PARP1 protein]24124520
D010042OuabainOuabain results in increased cleavage of PARP1 protein24124520
C013690styrene oxidestyrene oxide results in increased cleavage of PARP1 protein11929631
C013690styrene oxidestyrene oxide results in increased cleavage of PARP1 protein17662326
D013449SulfonamidesSulfonamides analog results in increased cleavage of PARP1 protein15826604
C016766sulforafanAcetylcysteine inhibits the reaction [[sulforafan co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]22922937
C016766sulforafan[sulforafan co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein22922937
C016766sulforafansulforafan inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein]21684301
D013467SulindacAcetylcysteine inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]18281123
D013467Sulindacpyrazolanthrone inhibits the reaction [[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein]18281123
D013467Sulindac[Sulindac co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein18281123
D013467SulindacSulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein]21882223
D013467SulindacSulindac results in increased activity of PARP1 protein15713900
C025462sulindac sulfideGW0742 promotes the reaction [sulindac sulfide results in increased cleavage of PARP1 protein]21400612
C025462sulindac sulfidesulindac sulfide results in decreased expression of PARP1 mRNA16184548
C025462sulindac sulfidesulindac sulfide results in increased cleavage of PARP1 protein12663503|1867861
C025462sulindac sulfidesulindac sulfide results in increased cleavage of PARP1 protein16886631
C473643sulphoraphenesulphoraphene results in increased cleavage of PARP1 protein29247643
D013629Tamoxifenalpha-Tocopherol inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]14645110
D013629TamoxifenSB 203580 inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein]14645110
D013629TamoxifenTamoxifen results in increased cleavage of PARP1 protein14645110
C021751tanshinoneAcetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]26203587
C021751tanshinoneDDIT3 mutant form inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]26203587
C021751tanshinonetanshinone promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]26203587
C021751tanshinonetanshinone results in increased cleavage of PARP1 protein26203587
C021751tanshinone[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein26203587
C021751tanshinoneTNFSF10 protein promotes the reaction [tanshinone results in increased cleavage of PARP1 protein]26203587
D013654TaurineTaurine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]19616567
D013654TaurineTaurine inhibits the reaction [sodium arsenite results in increased degradation of PARP1 protein]20830294
C031655tauroursodeoxycholic acid[Chenodeoxycholic Acid co-treated with tauroursodeoxycholic acid] results in increased cleavage of PARP1 protein14976352
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid inhibits the reaction [Quercetin promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]]25611565
C053079tautomycintautomycin inhibits the reaction [Docosahexaenoic Acids results in increased degradation of PARP1 protein]11341974
D013662TeaTea results in increased expression of PARP1 mRNA22181980
D013662TeaTea results in increased expression of PARP1 protein22181980
C047246temozolomidePARP1 protein affects the susceptibility to [temozolomide co-treated with veliparib]19825992
C047246temozolomidePARP1 protein results in decreased susceptibility to temozolomide21555580
D013739Testosteroneresveratrol inhibits the reaction [Testosterone results in increased expression of PARP1 protein]25714330
D013739TestosteroneTestosterone results in increased expression of PARP1 protein25714330
D013745Tetanus ToxoidTetanus Toxoid results in increased cleavage of PARP1 protein17286800
C000591600tetrachlorobenzoquinonetetrachlorobenzoquinone results in increased cleavage of PARP1 protein27484784
C000591600tetrachlorobenzoquinoneTNFRSF10B protein promotes the reaction [tetrachlorobenzoquinone results in increased cleavage of PARP1 protein]27484784
D013749Tetrachlorodibenzodioxin[3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
D013749Tetrachlorodibenzodioxin[3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D013749Tetrachlorodibenzodioxin[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
D013749Tetrachlorodibenzodioxin[benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D013749Tetrachlorodibenzodioxin[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD]17669606
D013749Tetrachlorodibenzodioxin[coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP]17669606
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PARP1 mRNA22574217
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased ADP-ribosylation of and results in increased activity of PARP1 protein17669606
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PARP1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PARP1 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PARP1 promoter]19654925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of PARP1 mRNA19465110
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [Camptothecin results in increased cleavage of PARP1 protein]25843524
C117155tetracycline CMT-3Celecoxib promotes the reaction [tetracycline CMT-3 results in increased cleavage of and results in increased expression of PARP1 protein]15688368
C117155tetracycline CMT-3tetracycline CMT-3 promotes the reaction [Celecoxib results in increased cleavage of and results in increased expression of PARP1 protein]15688368
C117155tetracycline CMT-3tetracycline CMT-3 results in increased cleavage of and results in increased expression of PARP1 protein15688368
D013755Tetradecanoylphorbol Acetate3-aminobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2120135|2126186
D013755Tetradecanoylphorbol AcetateButylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2126186
D013755Tetradecanoylphorbol AcetateCAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2126186
D013755Tetradecanoylphorbol Acetate[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of PARP1 protein17309078
D013755Tetradecanoylphorbol AcetateIndomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]2126186
D013755Tetradecanoylphorbol AcetatePARP1 protein affects the susceptibility to Tetradecanoylphorbol Acetate16323285
D013755Tetradecanoylphorbol Acetate"Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
D013755Tetradecanoylphorbol Acetate"Tetradecanoylphorbol Acetate promotes the reaction [cholix toxin, Vibrio cholerae results in increased cleavage of PARP1 protein]"28087840
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased activity of PARP1 protein2120135|2126186
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PARP1 mRNA25613284
D009025Morpholines3-methyladenine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein]24875536
D009025MorpholinesAcetylcysteine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein]24875536
D009025MorpholinesMorpholines analog results in increased cleavage of PARP1 protein24875536
C050950tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complextetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein]19286953
C017953tetramethylpyrazinetetramethylpyrazine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]26404762
C009438tetrandrinetetrandrine results in increased cleavage of PARP1 protein26822499
D013792Thalidomide[Curcumin co-treated with Thalidomide] results in increased cleavage of PARP1 protein19372569
D013792ThalidomideThalidomide analog results in increased cleavage of PARP1 protein15858615
C042172thallium nitrateEGF protein inhibits the reaction [thallium nitrate analog results in increased cleavage of PARP1 protein]27412756
C042172thallium nitrateEGF protein inhibits the reaction [thallium nitrate results in increased cleavage of PARP1 protein]27412756
C042172thallium nitratethallium nitrate analog results in increased cleavage of PARP1 protein19371624|2741275
C042172thallium nitratethallium nitrate results in increased cleavage of PARP1 protein19371624|2741275
D019284Thapsigargin[orlistat co-treated with Thapsigargin] results in increased cleavage of PARP1 protein17283163
D019284ThapsigarginApigenin inhibits the reaction [Thapsigargin results in increased cleavage of PARP1 protein]20493918
D019284ThapsigarginThapsigargin results in increased cleavage of PARP1 protein20493918
D013806Theophylline[Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein]9454737
D013806TheophyllineTheophylline binds to PARP1 protein18951874
C001996thermozymocidinthermozymocidin inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]24264887
C475227thieno(2,3-c)isoquinolin-5-one"thieno(2,3-c)isoquinolin-5-one results in decreased activity of PARP1 protein"13679179
C475227thieno(2,3-c)isoquinolin-5-one"thieno(2,3-c)isoquinolin-5-one results in decreased activity of PARP1 protein"17438151
C475227thieno(2,3-c)isoquinolin-5-one"thieno(2,3-c)isoquinolin-5-one results in decreased activity of PARP1 protein"12606624|1757905
D013883Thiostrepton[Thiostrepton co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein18297286
D013852ThiotepaNiacinamide inhibits the reaction [Thiotepa results in increased cleavage of PARP1 protein]22164206
D013852ThiotepaThiotepa results in increased cleavage of PARP1 protein22164206
C066185tingenin Btingenin B results in increased cleavage of PARP1 protein27720947
C009495titanium dioxidetitanium dioxide results in increased cleavage of PARP1 protein20362650
C009495titanium dioxidetitanium dioxide results in increased expression of PARP1 mRNA20362650
C423915TO-901317PARP1 protein inhibits the reaction [TO-901317 results in increased expression of ABCA1 mRNA]27026705
C423915TO-901317PARP1 protein inhibits the reaction [TO-901317 results in increased expression of ABCA1 mRNA]27026705
C423915TO-901317TO-901317 promotes the reaction [PARP1 protein binds to ABCA1 promoter]27026705
C423915TO-901317TO-901317 promotes the reaction [PARP1 protein binds to ABCG1 promoter]27026705
C423915TO-901317TO-901317 promotes the reaction [PARP1 protein binds to SREBF1 promoter]27026705
C423915TO-901317TO-901317 inhibits the reaction [Palmitates results in increased cleavage of PARP1 protein]21209018
C036454toosendanintoosendanin results in increased expression of PARP1 protein modified form23111283
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of PARP1 mRNA25729387
D014108Tosylphenylalanyl Chloromethyl KetoneAcetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein]19679660
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein19679660
D014148Tranexamic AcidTranexamic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]19539006
D014212TretinoinLTF protein inhibits the reaction [Tretinoin results in increased cleavage of PARP1 protein]16168621
D014212TretinoinTretinoin results in increased cleavage of PARP1 protein16168621
D014212Tretinoin[IDH1 protein affects the susceptibility to Tretinoin] which affects the cleavage of PARP1 protein26951332
D014212Tretinoin[IFNB1 protein co-treated with Tretinoin] results in increased cleavage of PARP1 protein16826196
D014212TretinoinTretinoin inhibits the reaction [geldanamycin results in increased degradation of PARP1 protein]17293044
D014212TretinoinTretinoin results in increased cleavage of PARP1 protein14519626|1738734
D014212TretinoinTretinoin promotes the reaction [pevonedistat results in increased cleavage of and results in increased activity of PARP1 protein]22110742
D014212TretinoinTretinoin results in increased cleavage of PARP1 protein21626648
C469689tricetintricetin results in decreased activity of PARP1 protein17884996
C012589trichostatin A[Bortezomib co-treated with trichostatin A] results in increased cleavage of and results in increased activity of PARP1 protein16904634
C012589trichostatin Atrichostatin A inhibits the reaction [Benzene results in decreased expression of PARP1 mRNA]20230882
C012589trichostatin Atrichostatin A inhibits the reaction [Benzene results in increased methylation of PARP1 promoter]20230882
C012589trichostatin Atrichostatin A results in increased acetylation of PARP1 protein27064363
C012589trichostatin Atrichostatin A results in increased cleavage of PARP1 protein17431121
C012589trichostatin Atrichostatin A results in increased degradation of PARP1 protein16010430
C012589trichostatin A[trichostatin A results in increased expression of GDF15 protein] which results in increased cleavage of PARP1 protein18801729
C012589trichostatin Atrichostatin A results in increased expression of PARP1 protein modified form23770000
C023764triciribinetriciribine inhibits the reaction [epothilone A results in increased expression of PARP1 mRNA]29117515
C023764triciribinetriciribine promotes the reaction [[epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA]29117515
C023764triciribinetriciribine results in increased expression of PARP1 mRNA29117515
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]21544200
D014271TrifluridineTrifluridine results in increased cleavage of PARP1 protein19816940
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of PARP1 mRNA19042947
C037718trimethyltin hydroxidetrimethyltin hydroxide results in increased cleavage of PARP1 protein16181675
C050414tripterineTNFRSF10A protein promotes the reaction [[TNFSF10 protein co-treated with tripterine] results in increased cleavage of PARP1 protein]20605676
C050414tripterineTNFRSF10B protein promotes the reaction [[TNFSF10 protein co-treated with tripterine] results in increased cleavage of PARP1 protein]20605676
C050414tripterine[TNFSF10 protein co-treated with tripterine] results in increased cleavage of PARP1 protein20605676
C001899triptolidetriptolide results in increased cleavage of PARP1 protein15972136
C001899triptolidetriptolide results in increased expression of PARP1 protein26990902
C084079triptonidetriptonide results in increased cleavage of PARP1 protein28666825
C057693troglitazoneAspirin promotes the reaction [troglitazone results in increased cleavage of PARP1 protein]19908241
C057693troglitazonetroglitazone promotes the reaction [Aspirin results in increased cleavage of PARP1 protein]19908241
C057693troglitazonetroglitazone results in increased cleavage of PARP1 protein19908241
C057693troglitazonetroglitazone results in increased expression of PARP112680223
C113580U 0126[U 0126 co-treated with Emodin] results in increased cleavage of PARP1 protein27032576
C113580U 0126U 0126 inhibits the reaction [BPDE-II results in increased cleavage of PARP1 protein]15572374
C113580U 0126"U 0126 inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]"28087840
C113580U 0126U 0126 inhibits the reaction [Emodin results in increased cleavage of PARP1 protein]27032576
C113580U 0126U 0126 inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]25246272
C113580U 0126U 0126 inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein]14688022
C113580U 0126U 0126 promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]27539140
C113580U 0126U 0126 promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]15557793
C113580U 0126U 0126 promotes the reaction [Flavanones results in increased cleavage of PARP1 protein]21616090
C113580U 0126U 0126 results in increased cleavage of PARP1 protein15557793
C113580U 0126U 0126 inhibits the reaction [cadmium acetate results in increased cleavage of PARP1 protein]24577723|2504395
C113580U 0126U 0126 inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]18775851
D014451Ubiquinone[Niacin co-treated with Ubiquinone co-treated with Riboflavin] results in increased expression of PARP1 protein18377693
C111601ultra-high molecular weight polyethylene[pamidronate co-treated with ultra-high molecular weight polyethylene] results in increased cleavage of PARP1 protein12507583
D014580Ursodeoxycholic Acidbenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
D014580Ursodeoxycholic AcidFADD mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
D014580Ursodeoxycholic Acidmethyl-beta-cyclodextrin inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
D014580Ursodeoxycholic Acid[oxaliplatin co-treated with Ursodeoxycholic Acid] results in increased cleavage of PARP1 protein19728331
D014580Ursodeoxycholic AcidRIPK1 mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
D014580Ursodeoxycholic AcidTNFRSF10B mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein]21362627
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in increased cleavage of PARP1 protein21362627
C005466ursolic acidursolic acid results in increased cleavage of PARP1 protein16012738
C406224valdecoxibvaldecoxib results in increased expression of PARP1 mRNA24136188
D014635Valproic Acid[Hydralazine co-treated with Valproic Acid] results in increased expression of PARP1 mRNA17183730
D014635Valproic AcidValproic Acid results in increased cleavage of PARP1 protein24913804
D014640Vancomycin"1,5-dihydroxyisoquinoline inhibits the reaction [Vancomycin results in increased expression of PARP1 protein]"19833176
D014640VancomycinVancomycin results in increased expression of PARP1 protein19833176
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of PARP1 gene25560391
D001335Vehicle EmissionsVehicle Emissions results in increased expression of PARP1 mRNA24216475
C521013veliparibPARP1 protein affects the susceptibility to [temozolomide co-treated with veliparib]19825992
C521013veliparibveliparib inhibits the reaction [Hydrogen Peroxide affects the reaction [PARP1 protein mutant form affects the abundance of NAD]]27694308
C521013veliparibveliparib inhibits the reaction [PARP1 protein mutant form affects the abundance of NAD]27694308
C521013veliparibveliparib inhibits the reaction [PARP1 protein mutant form results in increased expression of H2AFX protein modified form]27694308
C521013veliparibveliparib inhibits the reaction [PARP1 protein mutant form results in increased expression of RPA2 protein modified form]27694308
C521013veliparibveliparib results in decreased activity of PARP1 protein17505006|1914356
C521013veliparibveliparib results in increased expression of PARP1 protein19823047
C521013veliparibveliparib results in increased expression of PARP1 protein mutant form27694308
C521013veliparib[veliparib results in increased expression of PARP1 protein] which results in increased expression of H2AFX protein17505006
C521013veliparibveliparib results in decreased activity of PARP1 protein22158865
C521013veliparib[veliparib results in decreased activity of PARP1 protein] which results in increased susceptibility to Camptothecin22158865
C521013veliparibveliparib results in decreased activity of PARP1 protein17473206|2141734
C551177vemurafenibAZD 6244 inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of PARP1 protein]]27222248
C551177vemurafenib[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of PARP1 protein]27222248
C551177vemurafenibRAF1 protein affects the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] promotes the reaction [TNFRSF10B protein results in increased cleavage of PARP1 protein]]27222248
D014700VerapamilAcetylcysteine inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]24373880
D014700Verapamilbenzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]24373880
D014700Verapamil[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein24373880
D014700VerapamilVerapamil inhibits the reaction [PARP1 gene mutant form results in decreased uptake of Doxorubicin]15861398
D014747VinblastineCD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]16545138
D014747VinblastineVinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]16545138
C025643vinclozolinvinclozolin results in decreased expression of PARP1 mRNA23034163
D014757Viper VenomsViper Venoms results in increased cleavage of PARP1 protein27613483
D014800VitalliumVitallium analog results in decreased expression of PARP1 mRNA23825117
D012256Riboflavin[Niacin co-treated with Ubiquinone co-treated with Riboflavin] results in increased expression of PARP1 protein18377693
D012256RiboflavinRiboflavin analog results in increased cleavage of PARP1 protein20688149
D009536Niacinamide[Berberine co-treated with Niacinamide] results in increased cleavage of PARP1 protein26712469
D009536NiacinamideNiacinamide results in increased cleavage of PARP1 protein26712469
D009536NiacinamideNiacinamide inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of PARP1 protein]19288225
D009536NiacinamideNiacinamide inhibits the reaction [Excitatory Amino Acid Agonists results in increased activity of PARP1 protein]19288225
D009536NiacinamideNiacinamide inhibits the reaction [Methylnitrosourea results in increased activity of PARP1 protein]16168987
D009536NiacinamideNiacinamide inhibits the reaction [Thiotepa results in increased cleavage of PARP1 protein]22164206
D009536NiacinamideNiacinamide results in decreased activity of PARP1 protein19288225
D009536NiacinamideNiacinamide results in decreased activity of PARP1 protein7590113|8742498
D009536NiacinamidePARP1 protein affects the chemical synthesis of Niacinamide16026317
D002762CholecalciferolCholecalciferol affects the expression of PARP1 protein18628207
D014810Vitamin EVitamin E inhibits the reaction [Benzo(a)pyrene results in increased expression of PARP1 protein]24664296
D014810Vitamin EVitamin E inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]28237877
D014810Vitamin EVitamin E results in increased expression of PARP1 mRNA19244175
D024483Vitamin K 3[sodium arsenite co-treated with Vitamin K 3] results in increased cleavage of PARP1 protein19082730
D024483Vitamin K 3PARP1 protein affects the susceptibility to Vitamin K 321124846
C111237vorinostatBCL2 protein inhibits the reaction [vorinostat results in increased cleavage of PARP1 protein]21527555
C111237vorinostat[Bortezomib co-treated with vorinostat] results in increased degradation of PARP1 protein12893773
C111237vorinostatCDKN1C mutant form inhibits the reaction [[(+)-JQ1 compound co-treated with vorinostat] results in increased cleavage of PARP1 protein]26390243
C111237vorinostat[(+)-JQ1 compound co-treated with vorinostat] results in increased cleavage of PARP1 protein26390243
C111237vorinostat[vorinostat co-treated with resveratrol] results in increased cleavage of PARP1 protein22923501
C111237vorinostatvorinostat inhibits the reaction [BCL2 protein inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein]]19631782
C111237vorinostatvorinostat promotes the reaction [TNF protein results in increased cleavage of PARP1 protein]16377638
C111237vorinostatvorinostat results in increased cleavage of PARP1 protein15897598|1743112
D014859WarfarinWarfarin results in increased expression of PARP1 protein modified form26206560
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased expression of PARP1 mRNA"23063069
C051122wedelolactoneAcetylcysteine inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
C051122wedelolactoneButhionine Sulfoximine promotes the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
C051122wedelolactoneCAT protein inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
C051122wedelolactoneS-ethyl glutathione inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]22733624
C051122wedelolactonewedelolactone results in increased cleavage of PARP1 protein22733624
C051122wedelolactonewedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]25631491
C009684withaferin ADithiothreitol inhibits the reaction [withaferin A results in increased cleavage of PARP1 protein]20438634
C009684withaferin AMCL1 mutant form promotes the reaction [withaferin A results in increased cleavage of PARP1 protein]24019090
C009684withaferin Awithaferin A results in increased cleavage of PARP1 protein20438634|2401909
C009687wortmanninwortmannin promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]17935137
C009687wortmanninwortmannin promotes the reaction [Etoposide results in increased cleavage of PARP1 protein]17935137
C009687wortmanninwortmannin promotes the reaction [sodium arsenite results in increased degradation of PARP1 protein]12614848
C009687wortmanninwortmannin inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein]22155090
C519885WP1066WP1066 results in increased cleavage of PARP1 protein18056455|1824554
C104426WP 631WP 631 results in increased cleavage of PARP1 protein24287111
C451735WP 744WP 744 results in increased cleavage of PARP1 protein15555623
C104536xanthohumolxanthohumol results in increased cleavage of PARP1 protein15995977
D015018YtterbiumYtterbium analog results in increased cleavage of PARP1 protein19632212
C403304zerumbonezerumbone analog results in increased cleavage of PARP1 protein28987329
C403304zerumbonezerumbone results in increased cleavage of PARP1 protein16007145
D015032ZincCisplatin inhibits the reaction [Zinc binds to PARP1 protein]21370912
D015032ZincDopamine promotes the reaction [Zinc deficiency results in increased cleavage of PARP1 protein]23377617
D015032Zincimidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III) inhibits the reaction [Zinc binds to PARP1 protein]21370912
D015032Zinc"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to PARP1 protein]"24275069
D015032ZincOrganogold Compounds inhibits the reaction [Zinc binds to PARP1 protein]21370912
D015032ZincPARP1 protein modified form binds to Zinc25549802
D015032ZincRAPTA-T inhibits the reaction [Zinc binds to PARP1 protein]21370912
D015032Zincsodium arsenite inhibits the reaction [Zinc binds to PARP1 protein]24275069|2855277
D015032ZincZinc affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]15966574
D015032ZincZinc binds to and results in increased activity of PARP1 protein28552776
D015032ZincZinc binds to PARP1 protein24275069
D015032ZincZinc deficiency promotes the reaction [Dopamine results in increased cleavage of PARP1 protein]23377617
D015032ZincZinc deficiency results in increased cleavage of PARP1 protein23377617
D015032ZincZinc inhibits the reaction [arsenite results in decreased activity of PARP1 protein]18707137
D015032ZincZinc inhibits the reaction [monomethylarsonous acid results in decreased activity of PARP1 protein]21925530
D015032ZincZinc inhibits the reaction [sodium arsenite inhibits the reaction [Zinc binds to PARP1 protein]]24275069
D015032ZincZinc inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]24275069|2855277
D015032ZincZinc results in increased cleavage of PARP1 protein16472982|1679906
D015032ZincPARP1 protein affects the reaction [Zinc results in decreased abundance of Adenosine Triphosphate]17728843
D015032ZincPARP1 protein affects the reaction [Zinc results in decreased uptake of Excitatory Amino Acid Agents]17728843
D015032ZincZinc inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]26443841
D015032Zinc"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc results in decreased expression of PARP1 protein]"16799065
D015032ZincMetipranolol inhibits the reaction [Zinc results in decreased expression of PARP1 protein]16799065
D015032ZincZinc results in decreased expression of PARP1 protein16799065
C016837zinc chloridezinc chloride inhibits the reaction [cobaltous chloride inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein]]19714248
C016837zinc chloridezinc chloride inhibits the reaction [sodium arsenite results in decreased activity of PARP1 protein]19056730
C016837zinc chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]"22253048
C016837zinc chlorideacetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]18509044
C016837zinc chlorideCibacron Blue F 3GA inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]22253048
C016837zinc chloridecoomassie Brilliant Blue inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]22253048
C016837zinc chlorideNCF1 gene mutant form inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]18509044
C016837zinc chloride"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]"22253048
C016837zinc chloride"N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]"18509044
C016837zinc chloridePARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of ADGRE1 protein]18509044
C016837zinc chloridePARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of CSF2 protein]18509044
C016837zinc chloridePARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1A protein]18509044
C016837zinc chloridePARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL1B protein]18509044
C016837zinc chloridePARP1 gene mutant form inhibits the reaction [zinc chloride results in increased expression of IL3 protein]18509044
C016837zinc chloridePARP1 results in increased susceptibility to zinc chloride18509044
C016837zinc chlorideperiodate-oxidized adenosine 5'-triphosphate inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]22253048
C016837zinc chloride"pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]"22253048
C016837zinc chloridezinc chloride results in increased activity of PARP1 protein18509044
C016837zinc chloridezinc chloride results in increased expression of PARP1 protein22253048
D015034Zinc OxideAcetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of PARP1 protein]24614525
D015034Zinc OxideZinc Oxide analog results in increased cleavage of PARP1 protein24614525
D019287Zinc SulfateZinc Sulfate results in increased cleavage of PARP1 protein16799065
D019287Zinc Sulfate"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein]"16799065
D019287Zinc SulfateMetipranolol inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein]16799065
D019287Zinc SulfateZinc Sulfate results in decreased expression of PARP1 protein16799065
C097270ZM 241385ZM 241385 inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]24704558
C088658zoledronic acidarsenic trioxide promotes the reaction [zoledronic acid results in increased cleavage of PARP1 protein]20977926
C088658zoledronic acidzoledronic acid results in increased cleavage of PARP1 protein10780527|2097792
C088658zoledronic acidzoledronic acid results in increased expression of PARP1 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding-IDA11112786  
GO:0001228transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding-IDA11112786  
GO:0003677DNA binding-TAS2513174  
GO:0003723RNA binding-HDA22658674  22681889  
GO:0003950NAD+ ADP-ribosyltransferase activity-IDA16107709  17396150  19470756  23275542  
GO:0003950NAD+ ADP-ribosyltransferase activity-IMP22504299  
GO:0003950NAD+ ADP-ribosyltransferase activity-TAS-  
GO:0005515protein binding-IPI7596430  9518481  11248244  12898523  14596914  14627987  
14734561  15044383  15555565  16490787  17167422  17396150  
18172500  18971944  19661379  19666485  19710015  19779455  
20098424  20133863  21266351  21549307  21575865  21577210  
22504299  22863007  23230272  23396353  23481255  23966166  
24778456  25533949  25640309  25749521  27067600  27728808  
28190768  
GO:0008134transcription factor binding-IPI19303849  
GO:0008270zinc ion binding-IEA-  
GO:0019899enzyme binding-IPI23382074  
GO:0019901protein kinase binding-IPI17177976  
GO:0030331estrogen receptor binding-IEA-  
GO:0042802identical protein binding-IPI14734561  23481255  
GO:0042826histone deacetylase binding-IEA-  
GO:0047485protein N-terminus binding-IPI16107709  
GO:0051287NAD binding-IEA-  
GO:0070412R-SMAD binding-IEA-  
GO:1990404protein ADP-ribosylase activity-IDA28190768  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-TAS-  
GO:0000715nucleotide-excision repair, DNA damage recognition-TAS-  
GO:0000723telomere maintenance-TAS25749521  
GO:0000724double-strand break repair via homologous recombination-TAS-  
GO:0006281DNA repair-TAS17396150  
GO:0006293nucleotide-excision repair, preincision complex stabilization-TAS-  
GO:0006294nucleotide-excision repair, preincision complex assembly-TAS-  
GO:0006296nucleotide-excision repair, DNA incision, 5'-to lesion-TAS-  
GO:0006302double-strand break repair-IMP23230272  
GO:0006366transcription by RNA polymerase II-TAS10944198  
GO:0006471protein ADP-ribosylation-IDA17396150  27067600  
GO:0006471protein ADP-ribosylation-IMP22504299  
GO:0006915apoptotic process-IDA15565177  
GO:0006974cellular response to DNA damage stimulus-IMP24289924  24550317  27067600  
GO:0007005mitochondrion organization-IMP25378300  
GO:0007179transforming growth factor beta receptor signaling pathway-IEA-  
GO:0010332response to gamma radiation-IEA-  
GO:0010613positive regulation of cardiac muscle hypertrophy-ISS-  
GO:0010990regulation of SMAD protein complex assembly-IEA-  
GO:0016540protein autoprocessing-IEA-  
GO:0018312peptidyl-serine ADP-ribosylation-IDA28190768  
GO:0023019signal transduction involved in regulation of gene expression-IEA-  
GO:0030225macrophage differentiation-TAS18309324  
GO:0032042mitochondrial DNA metabolic process-IMP25378300  
GO:0032869cellular response to insulin stimulus-IDA19303849  
GO:0033148positive regulation of intracellular estrogen receptor signaling pathway-IEA-  
GO:0033683nucleotide-excision repair, DNA incision-TAS-  
GO:0034599cellular response to oxidative stress-IMP25378300  
GO:0034644cellular response to UV-IMP24289924  
GO:0036211protein modification process-IMP25378300  
GO:0042769DNA damage response, detection of DNA damage-IEA-  
GO:0043504mitochondrial DNA repair-IMP25378300  
GO:0044030regulation of DNA methylation-IEA-  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA11112786  
GO:0050790regulation of catalytic activity-IDA25749521  
GO:0051901positive regulation of mitochondrial depolarization-IEA-  
GO:0060391positive regulation of SMAD protein signal transduction-IEA-  
GO:0070212protein poly-ADP-ribosylation-IDA15674325  19470756  
GO:0070911global genome nucleotide-excision repair-TAS-  
GO:0071294cellular response to zinc ion-IEA-  
GO:1900182positive regulation of protein localization to nucleus-IEA-  
GO:1901216positive regulation of neuron death-IEA-  
GO:1903376regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-IEA-  
GO:1903518positive regulation of single strand break repair-IGI28002403  
GO:1903827regulation of cellular protein localization-IMP24550317  
GO:1904044response to aldosterone-IEA-  
GO:1904357negative regulation of telomere maintenance via telomere lengthening-ISS-  
GO:1904646cellular response to amyloid-beta-IEA-  
GO:1904762positive regulation of myofibroblast differentiation-IEA-  
GO:1990966ATP generation from poly-ADP-D-ribose-IDA27257257  
GO:2000679positive regulation of transcription regulatory region DNA binding-IEA-  
GO:2001170negative regulation of ATP biosynthetic process-IMP24289924  
GO ID GO Term Qualifier Evidence PubMed
GO:0000784nuclear chromosome, telomeric region-HDA19135898  
GO:0005634nucleus-IDA17177976  22504299  
GO:0005635nuclear envelope-IDA9518481  
GO:0005654nucleoplasm-TAS-  
GO:0005667transcription factor complex-IDA19303849  
GO:0005730nucleolus-IDA9518481  16107709  
GO:0005739mitochondrion-IDA25378300  
GO:0016020membrane-HDA19946888  
GO:0032991protein-containing complex-IDA22504299  25378300  
GO:0032993protein-DNA complex-IDA22504299  
KEGG ID KEGG Term
hsa03410Base excision repair
Reactome ID Reactome Term Evidence
R-HSA-110362POLB-Dependent Long Patch Base Excision RepairTAS
R-HSA-110373Resolution of AP sites via the multiple-nucleotide patch replacement pathwayTAS
R-HSA-162582Signal TransductionTAS
R-HSA-170834Signaling by TGF-beta Receptor ComplexTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2173793Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimerTAS
R-HSA-2173795Downregulation of SMAD2/3:SMAD4 transcriptional activityTAS
R-HSA-2990846SUMOylationTAS
R-HSA-3108214SUMOylation of DNA damage response and repair proteinsTAS
R-HSA-3108232SUMO E3 ligases SUMOylate target proteinsTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-5685939HDR through MMEJ (alt-NHEJ)TAS
R-HSA-5693532DNA Double-Strand Break RepairTAS
R-HSA-5693538Homology Directed RepairTAS
R-HSA-5696394DNA Damage Recognition in GG-NERTAS
R-HSA-5696395Formation of Incision Complex in GG-NERTAS
R-HSA-5696398Nucleotide Excision RepairTAS
R-HSA-5696399Global Genome Nucleotide Excision Repair (GG-NER)TAS
R-HSA-5696400Dual Incision in GG-NERTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-73884Base Excision RepairTAS
R-HSA-73894DNA RepairTAS
R-HSA-73933Resolution of Abasic Sites (AP sites)TAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-9006936Signaling by TGF-beta family membersTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22850545Selected polymorphisms of base excision repair genes and pancreatic cancer risk in Japanese. (2012)Nakao MJ Epidemiol
22740911Single nucleotide polymorphisms in DNA repair genes and risk of cervical cancer: A case-control study. (2012 Feb)Zhang LOncol Lett
23073772Racial and tissue-specific cancer risk associated with PARP1 (ADPRT) Val762Ala polymorphism: a meta-analysis. (2012 Dec)Pabalan NMol Biol Rep
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