Gene info: ID 1432

Gene: MAPK14

GENE ID: 1432

Description: mitogen-activated protein kinase 14

Gene type: protein-coding

Location: 6p21.31

dbXrefs: Ensembl:ENSG00000112062 MIM:600289 Vega:OTTHUMG00000159806 UniprotKB:Q16539

RefSeq: NC_000006.12

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 7

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 2.173e-1 (AD) 5.224e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
FAM160B1	0.93
RALGAPB	0.927
RNF145	0.926
RANBP2	0.924
MIA3	0.922
RBBP5	0.922
KAT7	0.921
FOXJ3	0.92
UBP1	0.92
AP1G1	0.919

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
OR4F5	-0.588
OR4F29	-0.553
CTNNA3	-0.302
S100A1	-0.295
C5orf64	-0.293
KLRB1	-0.289
SOX3	-0.286
HEY2	-0.282
KLRC2	-0.276
ASB4	-0.276

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB01254	Dasatinib	Small Molecule	302962-49-8	Approved\|Investigational	Target
DB01761	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	Small Molecule		Experimental	Target
DB01807	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	Small Molecule		Experimental	Target
DB01948	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	Small Molecule		Experimental	Target
DB01953	Inhibitor of P38 Kinase	Small Molecule	-	Experimental	Target
DB01988	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	Small Molecule		Experimental	Target
DB02195	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	Small Molecule		Experimental	Target
DB02277	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	Small Molecule		Experimental	Target
DB02352	3-(Benzyloxy)Pyridin-2-Amine	Small Molecule		Experimental	Target
DB02873	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	Small Molecule		Experimental	Target
DB02984	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	Small Molecule		Experimental	Target
DB03044	1-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-Urea	Small Molecule		Experimental\|Investigational	Target
DB03110	2-Chlorophenol	Small Molecule		Experimental	Target
DB03980	4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole	Small Molecule		Experimental	Target
DB04338	SB220025	Small Molecule		Experimental	Target
DB04632	4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE	Small Molecule		Experimental	Target
DB04797	Triazolopyridine	Small Molecule	-	Experimental	Target
DB05157	KC706	Small Molecule	-	Investigational	Target
DB05412	Talmapimod	Small Molecule	309913-83-5	Investigational	Target
DB05470	VX-702	Small Molecule		Investigational	Target
DB06882	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea	Small Molecule		Experimental	Target
DB06940	N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide	Small Molecule	-	Experimental	Target
DB06991	N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide	Small Molecule		Experimental	Target
DB07138	Neflamapimod	Small Molecule	209410-46-8	Investigational	Target
DB07307	N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide	Small Molecule		Experimental	Target
DB07459	4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE	Small Molecule		Experimental	Target
DB07607	4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE	Small Molecule		Experimental	Target
DB07811	N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide	Small Molecule		Experimental	Target
DB07829	4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE	Small Molecule		Experimental	Target
DB07832	4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde	Small Molecule		Experimental	Target
DB07833	N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide	Small Molecule		Experimental	Target
DB07834	N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide	Small Molecule		Experimental	Target
DB07835	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide	Small Molecule		Experimental	Target
DB07941	PH-797804	Small Molecule	586379-66-0	Investigational	Target
DB07942	2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine	Small Molecule		Experimental	Target
DB07943	2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol	Small Molecule		Experimental	Target
DB08064	N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA	Small Molecule		Experimental	Target
DB08068	N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-	Small Molecule		Experimental	Target
DB08091	3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE	Small Molecule		Experimental	Target
DB08092	3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide	Small Molecule	-	Experimental	Target
DB08093	3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE	Small Molecule		Experimental	Target
DB08095	3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA	Small Molecule		Experimental	Target
DB08096	8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM	Small Molecule		Experimental	Target
DB08097	2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE	Small Molecule		Experimental	Target
DB08242	N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	Small Molecule		Experimental	Target
DB08349	N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide	Small Molecule		Experimental	Target
DB08351	N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide	Small Molecule		Experimental	Target
DB08352	6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine	Small Molecule		Experimental	Target
DB08395	2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE	Small Molecule		Experimental	Target
DB08423	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE	Small Molecule		Experimental	Target
DB08424	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE	Small Molecule		Experimental	Target
DB08521	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	Small Molecule		Experimental	Target
DB08522	4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE	Small Molecule		Experimental	Target
DB08730	3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE	Small Molecule		Experimental	Target

ID	Drug Name	Action	PubMed
C490191	11,11'-dideoxyverticilin	"11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of MAPK14 protein"	15963507
C490191	11,11'-dideoxyverticilin	"SB 203580 inhibits the reaction [11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of MAPK14 protein]"	15963507
C070379	1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	21544200
C070379	1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	21544200
C070379	1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	21544200
C070379	1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased activity of MAPK14 protein]"	21544200
C049325	1,2-dithiol-3-thione	"1,2-dithiol-3-thione results in increased expression of MAPK14 mRNA"	19162173
C525468	1-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine	1-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine results in decreased activity of MAPK14 protein	20448081
C023350	1-iodo-2,4-dinitrobenzene	"1-iodo-2,4-dinitrobenzene results in increased phosphorylation of MAPK14 protein"	19427879
C447028	2,2',4,6-tetrachlorobiphenyl	"MAPK14 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]"	16120751
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAPK14 protein	15964311
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of MAPK14 protein	15631803
C408604	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole results in decreased activity of MAPK14 protein	14685156
C408604	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16000378
C408604	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole results in decreased phosphorylation of and results in decreased activity of MAPK14 protein	16000378
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of MAPK14 mRNA"	20702593
C484327	2'-benzoyloxycinnamaldehyde	2'-benzoyloxycinnamaldehyde results in increased phosphorylation of MAPK14 protein	14660655
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of MAPK14 mRNA]"	19467301
C108729	3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone	"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]"	17237268
C035419	3,4-dihydroxybenzohydroxamic acid	"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]"	25843059
C441128	3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate	"3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate affects the reaction [Dietary Fats affects the phosphorylation of MAPK14 protein]"	28899902
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [MAPK14 protein modified form results in increased phosphorylation of and results in increased activity of ATF2 protein]	9688607
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased susceptibility to MAPK14 protein modified form	9688607
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased activity of MAPK14 protein	10998351\|1524942
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Dexamethasone affects the localization of MAPK14 protein modified form]	20181797
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of MAPK14 protein	16046226
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased activity of MAPK14 protein	16046226
C522498	(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine	(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine results in decreased activity of MAPK14 protein	21449619
C108123	4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine	"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]"	17116659
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein	12684028
C027576	4-hydroxy-2-nonenal	Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]	12684028
C027576	4-hydroxy-2-nonenal	alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]	12684028
C027576	4-hydroxy-2-nonenal	Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]	12684028
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased expression of MAPK14 mRNA	19191707
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein	16322078
C027576	4-hydroxy-2-nonenal	resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16322078
C012358	4-hydroxycyclophosphamide	[afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of MAPK14 mRNA	25833159
C012606	4-vinyl-1-cyclohexene dioxide	4-vinyl-1-cyclohexene dioxide affects the expression of MAPK14 mRNA	20829426
C503119	5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone	5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK14 protein	15831436
C052026	6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole	"[6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole results in decreased phosphorylation of MAPK14 protein] which results in decreased expression of TOP2A protein"	15753397
D000082	Acetaminophen	Acetaminophen results in decreased expression of MAPK14 mRNA	21420995
D000082	Acetaminophen	Acetaminophen affects the expression of MAPK14 mRNA	17562736
D000109	Acetylcholine	MAPK14 protein affects the reaction [Acetylcholine results in increased activity of MAPKAPK2 protein]	9288946
D000109	Acetylcholine	Acetylcholine results in increased phosphorylation of and results in increased activity of MAPK14 protein	9688607
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]	12684028
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]	12684028
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]	17237268
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]	21635667
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]	21635667
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	18703135
D000111	Acetylcysteine	"Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"	28087840
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	14729614
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D000111	Acetylcysteine	"Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"	21635667
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK14 protein]	15650392
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	18703135
D000171	Acrolein	Acrolein results in increased phosphorylation of MAPK14 protein	17196791
D000171	Acrolein	Acrolein results in increased phosphorylation of MAPK14 protein	11329622\|1150470
D000171	Acrolein	tyrphostin AG 1478 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]	11329622
D000171	Acrolein	Acrolein results in increased phosphorylation of MAPK14 protein	12487375
D000171	Acrolein	[Acrolein results in increased phosphorylation of MAPK14 protein] which results in increased phosphorylation of ATF2 protein	12487375
D000171	Acrolein	SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]	12487375
C016601	afimoxifene	MAPK14 results in decreased susceptibility to afimoxifene	21233418
C016601	afimoxifene	[afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of MAPK14 mRNA	25833159
D000395	Air Pollutants, Occupational	"Air Pollutants, Occupational results in decreased expression of MAPK14 mRNA"	23195993
D000450	Aldosterone	MAPK14 protein affects the chemical synthesis of Aldosterone	14592955
D019386	Alendronate	Alendronate affects the expression of MAPK14 mRNA	16079270
D000493	Allopurinol	Allopurinol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of MAPK14 mRNA	17023530
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]	12684028
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]	12684028
D024502	alpha-Tocopherol	alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein]	14645110
C077990	alvocidib	[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK14 protein	15634644
D004999	Amifostine	Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein]	19010997
D006710	Homocysteine	Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766
D006710	Homocysteine	Atorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766\|2001828
D006710	Homocysteine	diphenyleneiodonium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766
D006710	Homocysteine	Homocysteine results in increased phosphorylation of MAPK14 protein	19767766\|2001828
D006710	Homocysteine	NOX4 mutant form inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	20018284
D006710	Homocysteine	SB 203580 inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766
D006710	Homocysteine	Atorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	20305681
D006710	Homocysteine	Homocysteine results in increased phosphorylation of MAPK14 protein	20305681
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of MAPK14 mRNA	16483693
C023650	aniline	aniline results in increased phosphorylation of MAPK14 protein	16169568\|1842024
D000841	Anisomycin	Anisomycin results in increased phosphorylation of and results in increased activity of MAPK14 protein	16364386
D000841	Anisomycin	Anisomycin results in increased phosphorylation of MAPK14 protein	10704466\|1603879
D000841	Anisomycin	MAPK14 protein affects the reaction [Anisomycin results in increased activity of MAPKAPK2 protein]	10704466
D000841	Anisomycin	Anisomycin results in increased phosphorylation of and results in increased activity of MAPK14 protein	15961565
D000968	Antimycin A	Antimycin A inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D016718	Arachidonic Acid	MAPK14 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]	19540902
D016718	Arachidonic Acid	MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]	19540902
D016718	Arachidonic Acid	MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]	19540902
D016718	Arachidonic Acid	"MAPK14 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]"	16120751
D001151	Arsenic	Arsenic affects the methylation of MAPK14 gene	25304211
C006632	arsenic trioxide	"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]"	17237268
C006632	arsenic trioxide	Acetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]	17237268
C006632	arsenic trioxide	Acetylcysteine inhibits the reaction [Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	14729614
C006632	arsenic trioxide	[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein	17237268
C006632	arsenic trioxide	arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein	12239215\|1461007
C006632	arsenic trioxide	Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	14729614
C006632	arsenic trioxide	MAPK14 mutant form inhibits the reaction [arsenic trioxide affects the localization of BAX protein]	18412143
C006632	arsenic trioxide	MAPK14 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of BCL2 protein]	18412143
C006632	arsenic trioxide	MAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]	18299328
C006632	arsenic trioxide	MAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein]	18299328
C006632	arsenic trioxide	MAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein]	18299328
C006632	arsenic trioxide	MAPK14 results in decreased susceptibility to arsenic trioxide	16818652
C006632	arsenic trioxide	PPM1D mutant form promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	18482988
C006632	arsenic trioxide	SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	14610070
C006632	arsenic trioxide	Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	14610070
C006632	arsenic trioxide	arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein	16818652
C006632	arsenic trioxide	MAP2K3 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16818652
C006632	arsenic trioxide	MAP2K6 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16818652
C006632	arsenic trioxide	arsenic trioxide inhibits the reaction [PPM1D protein results in decreased phosphorylation of MAPK14 protein]	18482988
C015001	arsenite	MAPK14 mutant form inhibits the reaction [arsenite results in increased ubiquitination of and results in increased degradation of CCNB1 protein]	17373649
C015001	arsenite	MAPK14 protein affects the reaction [arsenite promotes the reaction [EIF4E protein binds to EIF4G1 protein]]	12781867
C015001	arsenite	MAPK14 protein mutant form inhibits the reaction [CGP 57380 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]	12781867
C015001	arsenite	MAPK14 protein mutant form inhibits the reaction [SB 203580 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]	12781867
C015001	arsenite	arsenite results in increased phosphorylation of MAPK14 protein	17038550
D001194	Asbestos	Asbestos results in increased activity of MAPK14 protein	10660835
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in decreased expression of and results in decreased phosphorylation of MAPK14 protein"	17191120
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in decreased phosphorylation of and results in decreased activity of MAPK14 protein"	17507666
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein"	14962975\|1750766
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in increased phosphorylation of MAPK14 protein"	18314537
D017638	Asbestos, Crocidolite	"Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"	17507666
D017638	Asbestos, Crocidolite	"MAPK14 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of DUSP6 protein]"	18314537
D017638	Asbestos, Crocidolite	"SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	14962975
D017638	Asbestos, Crocidolite	"triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"	17507666
D017638	Asbestos, Crocidolite	"Vanadates inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"	17507666
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]	16407847
C022870	asoxime chloride	[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]	21971501
D001241	Aspirin	Aspirin promotes the reaction [IL1A results in increased phosphorylation of MAPK14 protein]	14742690
D001241	Aspirin	Aspirin results in increased phosphorylation of MAPK14 protein	14742690
D001241	Aspirin	IL1A promotes the reaction [Aspirin results in increased phosphorylation of MAPK14 protein]	14742690
D000069059	Atorvastatin Calcium	Atorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766\|2001828
D000069059	Atorvastatin Calcium	Atorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	20305681
D000069059	Atorvastatin Calcium	Atorvastatin Calcium inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]	17589825
D001280	Atrazine	Atrazine results in increased expression of MAPK14 mRNA	25929836
D001285	Atropine	[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]	21971501
C012765	bakuchiol	bakuchiol results in increased phosphorylation of and results in increased activity of MAPK14 protein	17292878
C030935	benz(a)anthracene	Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]	21635667
C030935	benz(a)anthracene	benz(a)anthracene results in increased phosphorylation of MAPK14 protein	21635667
C030935	benz(a)anthracene	SB 203580 inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]	21635667
D001548	Benzalkonium Compounds	Benzalkonium Compounds results in increased phosphorylation of MAPK14 protein	15737199
C017228	benzo(a)pyrene 7,8-dihydrodiol	"benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK14 protein"	15698582
C072019	benzo(a)pyrene diolepoxide I	benzo(a)pyrene diolepoxide I results in increased phosphorylation of MAPK14 protein	15698582
C022921	benzo(k)fluoranthene	Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]	21635667
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein	21635667
C022921	benzo(k)fluoranthene	SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]	21635667
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of MAPK14 mRNA	20702593
D001564	Benzo(a)pyrene	Benzo(a)pyrene metabolite results in increased expression of MAPK14 mRNA	26314263
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased phosphorylation of MAPK14 protein	15698582
D001564	Benzo(a)pyrene	MAPK14 protein promotes the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]	25233930
D004958	Estradiol	Estradiol results in increased activity of MAPK14 protein	15955695
C099952	bifenthrin	bifenthrin affects the expression of MAPK14 mRNA	26975043
C542674	bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)	"MAPK14 protein promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"	21548882
C070515	bisindolylmaleimide I	bisindolylmaleimide I inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]	16407847
C070515	bisindolylmaleimide I	bisindolylmaleimide I inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK14 protein]	15925026
C006780	bisphenol A	bisphenol A results in increased expression of MAPK14 mRNA	25181051
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in increased expression of MAPK14 mRNA	26314263
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in decreased expression of MAPK14 mRNA	17553608
D000069286	Bortezomib	[Bortezomib co-treated with Butyrates] results in increased phosphorylation of MAPK14 protein	12893773
D000069286	Bortezomib	[Bortezomib co-treated with vorinostat] results in increased phosphorylation of MAPK14 protein	12893773
D000069286	Bortezomib	MAPK14 mutant form inhibits the reaction [Bortezomib results in increased cleavage of CASP3 protein]	18790767
C439264	bovine serum albumin-corticosterone conjugate	bovine serum albumin-corticosterone conjugate results in increased phosphorylation of and results in increased activity of MAPK14 protein	15961565
C032036	bromobenzene	bromobenzene analog results in increased phosphorylation of MAPK14 protein	19427879
D016642	Bupropion	Bupropion results in increased phosphorylation of and results in increased activity of MAPK14 protein	21354251
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine results in increased phosphorylation of MAPK14 protein	17191120
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]	18691550
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]	18691550
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]	18691550
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]	18691550
D002084	Butylated Hydroxytoluene	Butylated Hydroxytoluene results in increased expression of MAPK14 mRNA	19925653
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in decreased expression of MAPK14 mRNA	15336504
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of MAPK14 mRNA	27509014
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased methylation of MAPK14 gene	27509014
D020122	tert-Butylhydroperoxide	"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]"	17116659
D020122	tert-Butylhydroperoxide	SB 203580 inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]	17116659
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein	17116659
D002087	Butyrates	[Bortezomib co-treated with Butyrates] results in increased phosphorylation of MAPK14 protein	12893773
D002087	Butyrates	Butyrates results in increased phosphorylation of and results in increased activity of MAPK14 protein	15978324
D002104	Cadmium	Cadmium promotes the reaction [MAPK14 protein results in increased phosphorylation of HSP27 protein]	17335952
D002104	Cadmium	Cadmium results in increased phosphorylation of MAPK14 protein	17335952
D002104	Cadmium	Cadmium results in increased phosphorylation of MAPK14 protein	20232314
D002104	Cadmium	SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of MAPK14 protein]	20232314
D002104	Cadmium	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased activity of MAPK14 protein]"	21544200
C028031	cadmium acetate	bisindolylmaleimide I inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK14 protein]	15925026
C028031	cadmium acetate	cadmium acetate affects the expression of MAPK14 mRNA	16249259
C028031	cadmium acetate	cadmium acetate results in increased phosphorylation of MAPK14 protein	15925026
D019256	Cadmium Chloride	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	21544200
D019256	Cadmium Chloride	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	18703135
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of MAPK14 mRNA	19757093
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein	21544200
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of MAPK14 protein	16264267\|1870313
D019256	Cadmium Chloride	Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D019256	Cadmium Chloride	MAPK14 gene mutant form inhibits the reaction [Cadmium Chloride results in increased ubiquitination of and results in increased degradation of CDC20 protein]	20054826
D019256	Cadmium Chloride	MAPK14 mutant form inhibits the reaction [Cadmium Chloride results in increased ubiquitination of and results in increased degradation of CDC20 protein]	20054826
D019256	Cadmium Chloride	salubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	21809093
D019256	Cadmium Chloride	SB 203580 inhibits the reaction [Cadmium Chloride results in decreased expression of MAPK14 mRNA]	19757093
D019256	Cadmium Chloride	Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D019256	Cadmium Chloride	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	21544200
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein	21544200
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of MAPK14 protein	18348256
D019256	Cadmium Chloride	Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D019256	Cadmium Chloride	[MAP2K4 co-treated with MAP2K7] affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	18348256
D019256	Cadmium Chloride	MAP2K4 mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	18348256
D019256	Cadmium Chloride	MAPK14 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]	10874044
D019256	Cadmium Chloride	MAPK14 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of HSPA1A protein]	18348256
D019256	Cadmium Chloride	MAPK14 mutant form inhibits the reaction [MAP2K7 mutant form promotes the reaction [Cadmium Chloride results in increased expression of HSPA1A protein]]	18348256
D019256	Cadmium Chloride	Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of MAPK14 protein	17027146
D019256	Cadmium Chloride	"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	21544200
D019256	Cadmium Chloride	Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	18703135
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein	21544200
D019256	Cadmium Chloride	Cadmium Chloride results in increased phosphorylation of MAPK14 protein	18703135\|2193318
D019256	Cadmium Chloride	CAMK2A mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	21933187
D019256	Cadmium Chloride	Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D019256	Cadmium Chloride	KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	21933187
D019256	Cadmium Chloride	Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D019256	Cadmium Chloride	MAPK14 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]	11709198
D019256	Cadmium Chloride	MAPK14 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]	11709198
D019256	Cadmium Chloride	MAPK14 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]	11709198
C058667	cadmium selenide	[cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK14 mRNA	22342292
C058667	cadmium selenide	[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein	22342292
C058667	cadmium selenide	NFKBIA protein inhibits the reaction [[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein]	22342292
C055494	caffeic acid phenethyl ester	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA	20360939
D000001	Calcimycin	2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16000378
D000001	Calcimycin	Calcimycin results in increased phosphorylation of and results in increased activity of MAPK14 protein	16000378
D002118	Calcium	Calcium affects the expression of MAPK14 mRNA	15913539
D002211	Capsaicin	Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein]	21745629
D002220	Carbamazepine	Carbamazepine affects the expression of MAPK14 mRNA	24752500
D002248	Carbon Monoxide	MAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]	11880364
D002248	Carbon Monoxide	MAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]	11880364
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased phosphorylation of MAPK14 protein	17285312
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of MAPK14 protein	17334410
D002251	Carbon Tetrachloride	FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	17334410
C043211	carvedilol	carvedilol inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]	16213474
D000068579	Celecoxib	[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK14 protein	16463383
C469298	CEP-11004	CEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	17698565
C466997	CGP 57380	MAPK14 protein mutant form inhibits the reaction [CGP 57380 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]	12781867
D002599	Chalcone	Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22155221
D002726	Chlorogenic Acid	Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein]	15944151
D002746	Chlorpromazine	Chlorpromazine analog results in decreased expression of MAPK14 mRNA	15924885
D002784	Cholesterol	[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA	25833014
D002784	Cholesterol	resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA]	25833014
C529269	cholix toxin, Vibrio cholerae	"Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"	28087840
C529269	cholix toxin, Vibrio cholerae	"cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein"	28087840
C529269	cholix toxin, Vibrio cholerae	"U 0126 inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"	28087840
C074702	chromium hexavalent ion	chromium hexavalent ion results in increased phosphorylation of MAPK14 protein	17045426
C039671	ciglitazone	[ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAPK14 mRNA	16197558
C012843	cinnamic aldehyde	cinnamic aldehyde results in increased phosphorylation of and results in increased activity of MAPK14 protein	15964311
C012843	cinnamic aldehyde	pyrazolanthrone inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]	15964311
C012843	cinnamic aldehyde	SB 203580 inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]	15964311
C012843	cinnamic aldehyde	cinnamic aldehyde results in decreased phosphorylation of MAPK14 protein	17486422
D003022	Clotrimazole	MAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]	27507784
D003024	Clozapine	Clozapine affects the expression of MAPK14 mRNA	15860345
C018021	cobaltous chloride	cobaltous chloride results in increased expression of MAPK14 mRNA	26314263
C018021	cobaltous chloride	MAPK14 mutant form inhibits the reaction [cobaltous chloride results in increased expression of NOS2 protein]	23624824
C018021	cobaltous chloride	MAPK14 mutant form inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]	23624824
D003042	Cocaine	Cocaine results in increased activity of MAPK14 protein	18952886
D003042	Cocaine	MAPK14 protein affects the susceptibility to Cocaine	10620750
C075384	coniferaldehyde	MAPK14 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]	26275128
C075384	coniferaldehyde	MAPK14 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]	26275128
D019327	Copper Sulfate	Copper Sulfate affects the expression of MAPK14 mRNA	19549813
C067957	corticosterone-21-hemisuccinate	corticosterone-21-hemisuccinate results in increased phosphorylation of and results in increased activity of MAPK14 protein	15961565
C477330	CP-654577	CP-654577 results in decreased expression of MAPK14 protein	12907618
C494620	CPS 11	CPS 11 results in increased phosphorylation of MAPK14 protein	15858615
C494622	CPS 49	CPS 49 results in increased phosphorylation of MAPK14 protein	15858615
C029892	cupric chloride	cupric chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein	17234613
C029892	cupric chloride	SB 203580 inhibits the reaction [cupric chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	17234613
D003474	Curcumin	Curcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]	17151092
D003474	Curcumin	MAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]	18357586
C057862	cyanoginosin LR	cyanoginosin LR results in increased phosphorylation of and results in increased activity of MAPK14 protein	22000993
C057862	cyanoginosin LR	cyanoginosin LR results in increased phosphorylation of MAPK14 protein	22000993
D003513	Cycloheximide	"Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"	17507666
D003520	Cyclophosphamide	[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA	16322899
D003520	Cyclophosphamide	Cyclophosphamide affects the expression of MAPK14 mRNA	18246545
D003520	Cyclophosphamide	Cyclophosphamide results in decreased expression of MAPK14 mRNA	18246545
D003545	Cysteine	[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein	11709198
D003545	Cysteine	SB 203580 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]	11709198
D003545	Cysteine	U 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]	11709198
D003545	Cysteine	MAPK14 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]	11709198
D003545	Cysteine	MAPK14 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]	11709198
D003545	Cysteine	MAPK14 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]	11709198
D000069439	Dasatinib	Dasatinib binds to MAPK14 protein	18180381
D003634	DDT	DDT results in increased phosphorylation of MAPK14 protein	14604893
C029415	deacylcortivazol	deacylcortivazol promotes the reaction [MAPK14 protein results in increased phosphorylation of NR3C1 protein]	15817653
C029415	deacylcortivazol	deacylcortivazol results in increased phosphorylation of and results in increased activity of MAPK14 protein	15817653
C007262	deoxynivalenol	deoxynivalenol results in increased expression of MAPK14 mRNA	20702593
C007262	deoxynivalenol	deoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK14 protein	16364386
C007262	deoxynivalenol	deoxynivalenol results in increased phosphorylation of MAPK14 protein	15976193
D003891	Desipramine	Desipramine results in increased activity of MAPK14 protein	18986328
D003907	Dexamethasone	Dexamethasone inhibits the reaction [Mitomycin results in increased activity of and results in increased phosphorylation of MAPK14 protein]	20002897
D003907	Dexamethasone	Dexamethasone promotes the reaction [MAPK14 protein results in increased phosphorylation of NR3C1 protein]	15817653
D003907	Dexamethasone	Dexamethasone results in increased activity of MAPK14 protein	11012613
D003907	Dexamethasone	Dexamethasone results in increased phosphorylation of and results in increased activity of MAPK14 protein	15817653
D003907	Dexamethasone	Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16880258
D003907	Dexamethasone	Dexamethasone results in increased expression of MAPK14 mRNA	22733784
D003907	Dexamethasone	DUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	16880258
D003907	Dexamethasone	[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of CAV1 protein]	14984747
D003907	Dexamethasone	[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of PPARG protein alternative form]	14984747
D003907	Dexamethasone	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Dexamethasone affects the localization of MAPK14 protein modified form]	20181797
D003907	Dexamethasone	Dexamethasone affects the localization of [MAPK14 protein modified form binds to FOXO1 protein]	20181797
D003907	Dexamethasone	Dexamethasone promotes the reaction [MAPK14 protein modified form binds to FOXO1 protein]	20181797
D003907	Dexamethasone	Dexamethasone results in decreased expression of MAPK14 protein	21094144
D003907	Dexamethasone	Dexamethasone results in increased phosphorylation of and affects the localization of MAPK14 protein	20181797
D003907	Dexamethasone	Testosterone inhibits the reaction [Dexamethasone results in decreased expression of MAPK14 protein]	21094144
D016190	Carboplatin	Carboplatin results in decreased expression of MAPK14 mRNA	18172885
D003975	Diazepam	[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]	21971501
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene results in increased phosphorylation of and results in increased activity of MAPK14 protein"	16005925
C041517	dibenzo(a,l)pyrene	"pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"	16005925
C041517	dibenzo(a,l)pyrene	"SB 203580 promotes the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"	16005925
C041517	dibenzo(a,l)pyrene	"U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"	16005925
D002945	Cisplatin	Cisplatin results in increased phosphorylation of MAPK14 protein	22006019
D004008	Diclofenac	Diclofenac affects the expression of MAPK14 mRNA	24752500
D004041	Dietary Fats	"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of MAPK14 mRNA]"	19467301
D004041	Dietary Fats	"3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate affects the reaction [Dietary Fats affects the phosphorylation of MAPK14 protein]"	28899902
D004041	Dietary Fats	Dietary Fats affects the phosphorylation of MAPK14 protein	28899902
D004041	Dietary Fats	Dietary Fats results in increased expression of MAPK14 mRNA	19467301
D004052	Diethylnitrosamine	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]	18691550
D004052	Diethylnitrosamine	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]	18691550
D004052	Diethylnitrosamine	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]	18691550
D004052	Diethylnitrosamine	Butylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of BAG3 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP4A12A mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DUSP4 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of HSPB1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of IKBKG mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of IRAK2 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of PLA2G16 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TRIB1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased abundance of Reactive Oxygen Species]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGT mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CARD10 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CASP9 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNH mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CITED2 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EFNA1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FGF1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FMO3 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45B mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HGF mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1B mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IRF1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of JUN mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAP2K4 protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAP2K7 protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein promotes the reaction [Diethylnitrosamine results in increased expression of HMOX1 protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein promotes the reaction [Diethylnitrosamine results in increased expression of HSBP1 mRNA]	18691550
D004052	Diethylnitrosamine	MAPK14 protein promotes the reaction [Diethylnitrosamine results in increased expression of HSBP1 protein]	18691550
D004052	Diethylnitrosamine	MAPK14 protein results in decreased susceptibility to Diethylnitrosamine	18691550
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA	20360939
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK14 mRNA	23830814
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK14 mRNA	23830814
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of MAPK14 mRNA	20360939
D004052	Diethylnitrosamine	[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of MAPK14 mRNA	18977376
D002117	Calcitriol	Calcitriol results in increased activity of MAPK14 protein	19748465
D002117	Calcitriol	CAMP mutant form inhibits the reaction [Calcitriol results in increased activity of MAPK14 protein]	19748465
D002117	Calcitriol	[CAMP results in increased activity of MAPK14] affects the reaction [Calcitriol results in increased expression of ATG5 mRNA]	19748465
D002117	Calcitriol	[CAMP results in increased activity of MAPK14] affects the reaction [Calcitriol results in increased expression of BECN1 mRNA]	19748465
D002117	Calcitriol	[Calcitriol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK14 protein	16598785
D002117	Calcitriol	Calcitriol results in increased phosphorylation of MAPK14 protein	16598785
D004137	Dinitrochlorobenzene	Dinitrochlorobenzene results in increased phosphorylation of MAPK14 protein	15737199
D004139	Dinitrofluorobenzene	Dinitrofluorobenzene results in increased phosphorylation of MAPK14 protein	19427879
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766
D004317	Doxorubicin	Doxorubicin affects the activity of MAPK14 protein	15870702
D004317	Doxorubicin	[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA	16322899
D004317	Doxorubicin	Doxorubicin promotes the reaction [MAPK14 protein results in decreased expression of BCL2L1 protein]	16843435
D004317	Doxorubicin	Doxorubicin promotes the reaction [MAPK14 protein results in decreased phosphorylation of BAD protein]	16843435
D004317	Doxorubicin	Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK14 protein	15494689\|1684343
D004317	Doxorubicin	Doxorubicin results in increased phosphorylation of MAPK14 protein	15557793
D004317	Doxorubicin	carvedilol inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]	16213474
D004317	Doxorubicin	Doxorubicin results in increased phosphorylation of MAPK14 protein	15767673\|1621347
D004317	Doxorubicin	Razoxane inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]	16213474
D004317	Doxorubicin	[SB 203580 results in decreased activity of MAPK14 protein] which results in decreased susceptibility to Doxorubicin	15936597
D004318	Doxycycline	Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein]	18089841
C060327	dracorhodin	dracorhodin analog results in increased phosphorylation of MAPK14 protein	15684474\|1686444
C060327	dracorhodin	SB 203580 inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK14 protein]	16864444
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased phosphorylation of MAPK14 protein"	15894585
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	17996413
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]"	28757890
D004391	Dust	Dust results in decreased expression of MAPK14 mRNA	17805423
D004533	Egtazic Acid	Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D004533	Egtazic Acid	Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D004533	Egtazic Acid	Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D004610	Ellagic Acid	Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein]	27965107
D004640	Emetine	Emetine results in increased phosphorylation of and results in increased activity of MAPK14 protein	16364386
D004640	Emetine	MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP2 protein]	26332055
D004640	Emetine	MAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP9 protein]	26332055
D004640	Emetine	MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK1 protein]	26332055
D004640	Emetine	MAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK3 protein]	26332055
D004642	Emodin	Acetylcysteine inhibits the reaction [Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	14729614
D004642	Emodin	Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	14729614
D004726	Endosulfan	Endosulfan results in increased phosphorylation of and results in increased activity of MAPK14 protein	22146149
C044101	endotoxin, Escherichia coli	"endotoxin, Escherichia coli results in increased phosphorylation of MAPK14 protein"	16919916
C044101	endotoxin, Escherichia coli	"Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of MAPK14 protein]"	16919916
D004785	Environmental Pollutants	Environmental Pollutants results in decreased expression of MAPK14 mRNA	12655031
C045651	epigallocatechin gallate	[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK14 protein	16463383
C045651	epigallocatechin gallate	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MAPK14 mRNA	22079256
D004875	Ergosterol	[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA	25833014
D004875	Ergosterol	resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA]	25833014
C007628	esculetin	[esculetin co-treated with Paclitaxel] results in decreased expression of MAPK14 protein	16051289
C007628	esculetin	esculetin results in decreased phosphorylation of and results in decreased activity of MAPK14 protein	16051289
D004976	Ethacrynic Acid	Ethacrynic Acid results in decreased expression of MAPK14 protein	14556662
D000431	Ethanol	MAPK14 protein promotes the reaction [Ethanol results in increased expression of and results in increased phosphorylation of TP53 protein]	27270636
D000431	Ethanol	MAPK14 protein promotes the reaction [Ethanol results in increased expression of CASP3 protein modified form]	27270636
D000431	Ethanol	MAPK14 protein results in increased susceptibility to Ethanol	27270636
D000431	Ethanol	Ethanol affects the expression of MAPK14 mRNA	11772933
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of MAPK14 mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of MAPK14 mRNA	16079270
D005015	Ethoxyquin	[Ethoxyquin results in increased expression of PRDX1 protein] which results in increased phosphorylation of MAPK14 protein	16880205
C456800	ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate	[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK14 protein	15634644
C013531	ferric ammonium citrate	ferric ammonium citrate results in increased phosphorylation of MAPK14 protein	17191120
D005473	Fluoxetine	Fluoxetine results in increased phosphorylation of MAPK14 protein	16413968
D005480	Flurbiprofen	MAPK14 protein promotes the reaction [Flurbiprofen results in increased expression of GDF15 protein]	21097678
D005480	Flurbiprofen	MAPK14 protein promotes the reaction [Flurbiprofen results in increased expression of NGFR protein]	18056468
D005480	Flurbiprofen	MAPK14 protein promotes the reaction [Flurbiprofen results in increased phosphorylation of EIF4E protein]	18056468
D005557	Formaldehyde	Formaldehyde results in increased phosphorylation of MAPK14 protein	15737199
D009240	N-Formylmethionine Leucyl-Phenylalanine	N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK14 protein	17406807
D009240	N-Formylmethionine Leucyl-Phenylalanine	Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein]	17406807
D009240	N-Formylmethionine Leucyl-Phenylalanine	N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein	16621998
C104334	FR 167653	FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	17334410
D037741	Fullerenes	Fullerenes analog results in increased expression of MAPK14 mRNA	22342292
D037741	Fullerenes	Fullerenes analog results in increased phosphorylation of MAPK14 protein	22342292
D037741	Fullerenes	NFKBIA protein inhibits the reaction [Fullerenes analog results in increased phosphorylation of MAPK14 protein]	22342292
D019833	Genistein	Genistein results in decreased expression of MAPK14 mRNA	21048042
D005839	Gentamicins	Gentamicins results in increased expression of MAPK14 mRNA	22061828
D005839	Gentamicins	Gentamicins results in increased expression of MAPK14 protein	16751989
D005944	Glucosamine	Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]	19626664
D005947	Glucose	CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]	17309078
D005947	Glucose	Glucose deficiency results in increased activity of MAPK14 protein	17309078
D005947	Glucose	Glucose results in decreased phosphorylation of MAPK14 protein	20200188
D005947	Glucose	MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of KRT20 protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of VIM protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in decreased expression of CDH1 protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 mRNA]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in increased expression of ACTA2 protein]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in increased expression of SNAI1 mRNA]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in increased expression of VIM mRNA]	21829520
D005947	Glucose	MAPK14 protein promotes the reaction [Glucose results in increased secretion of FN1 protein]	21829520
D005947	Glucose	Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]	17309078
D005947	Glucose	Glucose promotes the reaction [EIF2AK2 protein results in increased activity of MAPK14 protein]	18973755
D005947	Glucose	[resveratrol co-treated with Glucose] results in decreased expression of MAPK14 mRNA	24659233
D006220	Haloperidol	Haloperidol affects the expression of MAPK14 mRNA	15860345
D006221	Halothane	Halothane results in decreased expression of MAPK14 protein	24598351
D006221	Halothane	Halothane results in increased expression of MAPK14 mRNA	24598351
D006427	Hemin	Hemin inhibits the reaction [IL18 protein results in increased expression of MAPK14 protein]	18215737
D006581	Hexachlorobenzene	Hexachlorobenzene affects the expression of MAPK14 mRNA	15159207
D017313	Fenretinide	Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]	16407847
D017313	Fenretinide	bisindolylmaleimide I inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]	16407847
D017313	Fenretinide	Fenretinide results in increased activity of MAPK14 protein	16407847
D017313	Fenretinide	Fenretinide results in increased phosphorylation of MAPK14 protein	16407847
D006861	Hydrogen Peroxide	Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]	12684028
D006861	Hydrogen Peroxide	Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D006861	Hydrogen Peroxide	Allopurinol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D006861	Hydrogen Peroxide	alpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]	12684028
D006861	Hydrogen Peroxide	Antimycin A inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D006861	Hydrogen Peroxide	Hydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]	12684028
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK14 protein	12684028
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein	15650392
D006861	Hydrogen Peroxide	Rotenone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein	19010997
D006861	Hydrogen Peroxide	PRDX1 protein promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	16880205
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased activity of MAPK14 protein	15574683\|8971075
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein	16284289
D006861	Hydrogen Peroxide	Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	16284289
D006861	Hydrogen Peroxide	SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK14 protein]	8971075
D007052	Ibuprofen	MAPK14 protein promotes the reaction [Ibuprofen results in increased expression of GDF15 protein]	21097678
D007052	Ibuprofen	MAPK14 protein promotes the reaction [Ibuprofen results in increased expression of NGFR protein]	18056468
D007052	Ibuprofen	MAPK14 protein promotes the reaction [Ibuprofen results in increased phosphorylation of EIF4E protein]	18056468
D000068877	Imatinib Mesylate	Imatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
D000068877	Imatinib Mesylate	Imatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
C041508	indeno(1,2,3-cd)pyrene	"Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"	21635667
C041508	indeno(1,2,3-cd)pyrene	"indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein"	21635667
C041508	indeno(1,2,3-cd)pyrene	"SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"	21635667
C514526	indole-5-carboxamide	indole-5-carboxamide results in decreased activity of MAPK14 protein	15363871
D007545	Isoproterenol	Doxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein]	18089841
D007545	Isoproterenol	Isoproterenol results in increased phosphorylation of MAPK14 protein	18089841
C063587	juzentaihoto	juzentaihoto promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	15778123
D007657	Ketone Bodies	Ketone Bodies results in increased expression of MAPK14 mRNA	16807920
C072105	KN 93	KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	21933187
C508710	L-826266	L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK14 protein]	16644903
C008261	lead acetate	lead acetate affects the expression of MAPK14	24293362
C008281	limonene	limonene results in increased expression of MAPK14 mRNA	12815608
C440499	lipopolysaccharide, Escherichia coli O111 B4	"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]"	19549798
C440499	lipopolysaccharide, Escherichia coli O111 B4	"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]"	19549798
C440499	lipopolysaccharide, Escherichia coli O111 B4	"MAPK14 protein affects the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]"	19549798
C440499	lipopolysaccharide, Escherichia coli O111 B4	"MAPK14 protein affects the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]"	19549798
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of MAPK14 protein modified form	19041413
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased phosphorylation of MAPK14 protein	22053092
D008070	Lipopolysaccharides	ARHGEF2 mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22226621
D008070	Lipopolysaccharides	CEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	17698565
D008070	Lipopolysaccharides	DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]]	21911040
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased activity of MAPK14 protein	14997032
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased phosphorylation of MAPK14 protein	21911040\|2212417
D008070	Lipopolysaccharides	RHOA mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22226621
D008070	Lipopolysaccharides	SB 203580 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22226621
D008070	Lipopolysaccharides	telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22124178
D008070	Lipopolysaccharides	trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	21911040
D008070	Lipopolysaccharides	Y 27632 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22226621
D008070	Lipopolysaccharides	"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]"	25843059
D008070	Lipopolysaccharides	Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein]	19010997
D008070	Lipopolysaccharides	Chalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22155221
D008070	Lipopolysaccharides	Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16880258
D008070	Lipopolysaccharides	"Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]"	17996413
D008070	Lipopolysaccharides	DUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	16880258
D008070	Lipopolysaccharides	GSTP1 protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	16023107
D008070	Lipopolysaccharides	juzentaihoto promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	15778123
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein	19010997
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of MAPK14 mRNA	25843059
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein	16880258\|1799641
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased phosphorylation of MAPK14 protein	10704466\|1577812
D008070	Lipopolysaccharides	lycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22155741
D008070	Lipopolysaccharides	MAPK14 protein promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]	15795323
D008070	Lipopolysaccharides	methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	15933225
C015329	lycopene	lycopene results in decreased expression of MAPK14 protein	17337101
C015329	lycopene	lycopene results in increased expression of MAPK14 mRNA	16886892
C015330	lycorine	lycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22155741
C065861	malvidin	malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein	15964118
D008345	Manganese	Manganese results in decreased phosphorylation of MAPK14 protein	17043766
C025340	manganese chloride	manganese chloride results in increased phosphorylation of MAPK14 protein	15737199
C025340	manganese chloride	manganese chloride results in increased expression of MAPK14 mRNA	17467022
D000069997	Mastic Resin	[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of MAPK14 mRNA	18977376
D008627	Mercuric Chloride	Mercuric Chloride results in increased phosphorylation of MAPK14 protein	15585369
D008701	Methapyrilene	Methapyrilene results in decreased expression of MAPK14 mRNA	16393664
D008715	Methionine	[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein	11709198
D008715	Methionine	SB 203580 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]	11709198
D008715	Methionine	U 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]	11709198
D008715	Methionine	MAPK14 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]	11709198
D008715	Methionine	MAPK14 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]	11709198
D008715	Methionine	MAPK14 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]	11709198
D008727	Methotrexate	Methotrexate results in decreased expression of MAPK14 mRNA	19100307
D008727	Methotrexate	Methotrexate results in increased phosphorylation of MAPK14 protein	19100307
D008727	Methotrexate	SB 203580 inhibits the reaction [Methotrexate results in increased phosphorylation of MAPK14 protein]	19100307
C587228	methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate	methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate results in increased expression of and results in increased phosphorylation of MAPK14 protein	24291674
C014659	methyl(acetoxymethyl)nitrosamine	methyl(acetoxymethyl)nitrosamine results in increased phosphorylation of and results in increased activity of MAPK14 protein	12693035
C008435	methyldithiocarbamate	methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	15933225
C030957	methylmercury II	methylmercury II results in increased expression of MAPK14 mRNA	26314263
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of MAPK14 mRNA"	20188158
D008769	Methylnitronitrosoguanidine	Methylnitronitrosoguanidine results in increased phosphorylation of MAPK14 protein	22001597
D008770	Methylnitrosourea	Methylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK14 protein	12693035
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK14 protein	22019741
D016685	Mitomycin	Dexamethasone inhibits the reaction [Mitomycin results in increased activity of and results in increased phosphorylation of MAPK14 protein]	20002897
D016685	Mitomycin	Mitomycin results in increased activity of and results in increased phosphorylation of MAPK14 protein	20002897
C406082	monomethylarsonous acid	monomethylarsonous acid results in increased expression of MAPK14 mRNA	20024957
D009020	Morphine	Morphine results in increased expression of MAPK14 protein	23056601
D009151	Mustard Gas	MAPK14 mutant form inhibits the reaction [Mustard Gas results in increased expression of CXCL8 protein]	20143454
D009151	Mustard Gas	MAPK14 mutant form inhibits the reaction [Mustard Gas results in increased expression of IL6 protein]	20143454
D009151	Mustard Gas	MAPK14 mutant form inhibits the reaction [Mustard Gas results in increased expression of TNF protein]	20143454
D009151	Mustard Gas	MAPK14 protein affects the reaction [Mustard Gas results in increased expression of CXCL8 mRNA]	23851002
D009151	Mustard Gas	MAPK14 protein affects the reaction [Mustard Gas results in increased expression of IL6 mRNA]	23851002
D009151	Mustard Gas	MAPK14 protein affects the reaction [Mustard Gas results in increased expression of TNF mRNA]	23851002
D009151	Mustard Gas	MAPK14 protein affects the reaction [Mustard Gas results in increased secretion of CXCL8 protein]	23851002
D009151	Mustard Gas	MAPK14 protein affects the reaction [Mustard Gas results in increased secretion of IL1B protein]	23851002
D009151	Mustard Gas	MAPK14 protein affects the reaction [Mustard Gas results in increased secretion of IL6 protein]	23851002
D009151	Mustard Gas	MAPK14 protein affects the susceptibility to Mustard Gas	23851002
D009151	Mustard Gas	Mustard Gas results in increased expression of MAPK14 mRNA	15674844
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased phosphorylation of MAPK14 protein"	20800606
D009287	Naphthyridines	Naphthyridines analog affects the activity of MAPK14 protein	21999461
C017096	n-butoxyethanol	n-butoxyethanol results in decreased expression of MAPK14 mRNA	19812364
D009532	Nickel	Nickel results in decreased expression of MAPK14 mRNA	23195993
C022838	nickel chloride	nickel chloride results in increased phosphorylation of MAPK14 protein	15737199
D009605	Nitrosomethylurethane	Nitrosomethylurethane results in increased phosphorylation of and results in increased activity of MAPK14 protein	12693035
C404397	NSC 680410	NSC 680410 results in increased phosphorylation of MAPK14 protein	14647418
C025589	ochratoxin A	MAPK14 protein promotes the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]	22230261
C025589	ochratoxin A	MAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CCNB1 protein]	22230261
C025589	ochratoxin A	MAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDC25C protein]	22230261
C025589	ochratoxin A	MAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDC25C protein modified form]	22230261
C025589	ochratoxin A	MAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDK1 protein]	22230261
C025589	ochratoxin A	MAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDK1 protein modified form]	22230261
C025589	ochratoxin A	MAPK14 protein results in increased susceptibility to ochratoxin A	22230261
C025589	ochratoxin A	ochratoxin A metabolite results in increased expression of MAPK14 mRNA	26314263
C025589	ochratoxin A	ochratoxin A results in increased expression of MAPK14 mRNA	26314263
C031492	octanoic acid	[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of CAV1 protein]	14984747
C031492	octanoic acid	[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of PPARG protein alternative form]	14984747
D009828	Oleanolic Acid	Oleanolic Acid analog results in decreased phosphorylation of MAPK14 protein	26612655
D009853	Omeprazole	Omeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein]	17406807
C016340	o,p'-DDT	"MAPK14 protein promotes the reaction [o,p'-DDT results in increased activity of NOTCH1 protein]"	18791200
D017239	Paclitaxel	[esculetin co-treated with Paclitaxel] results in decreased expression of MAPK14 protein	16051289
D019308	Palmitic Acid	Capsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein]	21745629
D019308	Palmitic Acid	Palmitic Acid results in increased phosphorylation of MAPK14 protein	21745629
D010269	Paraquat	"Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of MAPK14 protein]"	16919916
D010269	Paraquat	Paraquat results in increased phosphorylation of MAPK14 protein	16797015\|1691991
D010269	Paraquat	[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK14 protein	24376630
D010269	Paraquat	Paraquat results in increased phosphorylation of MAPK14 protein	17324951\|1799788
D010416	Pentachlorophenol	Pentachlorophenol results in increased expression of MAPK14 mRNA	23892564
D010426	Pentosan Sulfuric Polyester	Pentosan Sulfuric Polyester results in increased expression of MAPK14 mRNA	28973697
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid affects the expression of MAPK14 mRNA	19196829
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of MAPK14 protein	28126411
C569762	PF 03715455	PF 03715455 binds to and results in decreased activity of MAPK14 protein	21888439
D015232	Dinoprostone	Dinoprostone results in increased activity of MAPK14 protein	16644903
D015232	Dinoprostone	L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK14 protein]	16644903
D015232	Dinoprostone	Dinoprostone results in increased phosphorylation of MAPK14 protein	18030065
D010634	Phenobarbital	Phenobarbital results in decreased expression of MAPK14 mRNA	12807726
D010656	Phenylephrine	Phenylephrine results in increased phosphorylation of MAPK14 protein	15757502
C003117	phosalone	Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein]	27965107
C003117	phosalone	phosalone results in increased expression of MAPK14 protein	27965107
C012491	phytosphingosine	"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]"	17237268
C012491	phytosphingosine	Acetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]	17237268
C012491	phytosphingosine	[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein	17237268
C121565	pifithrin	pifithrin results in increased phosphorylation of MAPK14 protein	16061640
C121565	pifithrin	"pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"	16005925
D010936	Plant Extracts	Plant Extracts results in increased expression of MAPK14 mRNA	23557933
D028321	Plant Preparations	Plant Preparations results in increased expression of MAPK14 mRNA	24973489
D011134	Polysaccharides	Polysaccharides results in increased phosphorylation of MAPK14 protein	15894585
C027373	potassium chromate(VI)	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MAPK14 mRNA	22079256
C027373	potassium chromate(VI)	potassium chromate(VI) results in decreased expression of MAPK14 mRNA	22079256
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in decreased expression of MAPK14 mRNA	19162173
D011374	Progesterone	Progesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	16284289
C518978	prostaglandin E2 glyceryl ester	prostaglandin E2 glyceryl ester results in increased phosphorylation of MAPK14 protein	17539917
C518978	prostaglandin E2 glyceryl ester	SB 239063 inhibits the reaction [prostaglandin E2 glyceryl ester results in increased phosphorylation of MAPK14 protein]	17539917
C107773	pterostilbene	"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]"	19549798
C107773	pterostilbene	"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]"	19549798
C034912	puag-haad	puag-haad results in increased expression of MAPK14 mRNA	28780155
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]	15964311
C432165	pyrazolanthrone	pyrazolanthrone results in decreased phosphorylation of MAPK14 protein	16046226
C432165	pyrazolanthrone	pyrazolanthrone results in increased expression of MAPK14 protein	16046226
D011720	Pyrazoles	Pyrazoles analog results in decreased activity of MAPK14 protein	12534346
D011743	Pyrimidines	Pyrimidines analog results in decreased activity of MAPK14 protein	12534346
D011794	Quercetin	Quercetin results in increased expression of MAPK14 protein modified form	22197970
D011794	Quercetin	MAPK14 protein promotes the reaction [Quercetin promotes the reaction [NR1H3 protein binds to ABCA1 promoter]]	22711909
D011794	Quercetin	MAPK14 protein promotes the reaction [Quercetin promotes the reaction [SP1 protein binds to ABCA1 promoter]]	22711909
D011794	Quercetin	MAPK14 protein promotes the reaction [Quercetin results in increased expression of ABCA1 mRNA]	22711909
D011794	Quercetin	MAPK14 protein promotes the reaction [Quercetin results in increased expression of ABCA1 protein]	22711909
D011799	Quinazolines	Quinazolines binds to and results in decreased activity of MAPK14 protein	18817365
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride affects the expression of MAPK14 mRNA	16079270
D011929	Razoxane	Razoxane inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]	16213474
D017382	Reactive Oxygen Species	Reactive Oxygen Species results in increased activity of MAPK14 protein	17237268
D017382	Reactive Oxygen Species	MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased abundance of Reactive Oxygen Species]	18691550
D017382	Reactive Oxygen Species	[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK14 protein	24376630
C059514	resveratrol	resveratrol results in decreased expression of MAPK14 protein	18089832
C059514	resveratrol	[resveratrol co-treated with Glucose] results in decreased expression of MAPK14 mRNA	24659233
C059514	resveratrol	resveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]	16322078
C059514	resveratrol	resveratrol affects the expression of MAPK14 mRNA	15748624
C059514	resveratrol	resveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA]	25833014
C009166	retinol acetate	retinol acetate results in increased expression of MAPK14 mRNA	16772331
D012402	Rotenone	Rotenone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]	15650392
D012402	Rotenone	Rotenone results in increased phosphorylation of and results in increased activity of MAPK14 protein	14976342
D012402	Rotenone	Rotenone results in increased phosphorylation of MAPK14 protein	17324951\|1977756
C085746	rottlerin	rottlerin results in decreased phosphorylation of MAPK14 protein	15949478
C085746	rottlerin	rottlerin results in decreased phosphorylation of MAPK14 protein	15949478
C010327	salinomycin	salinomycin results in decreased expression of MAPK14 mRNA	19682730
C496827	salubrinal	salubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]	21809093
C093642	SB 203580	SB 203580 results in decreased activity of MAPK14 protein	15659807
C093642	SB 203580	MAPK14 protein mutant form inhibits the reaction [SB 203580 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]	12781867
C093642	SB 203580	"SB 203580 inhibits the reaction [11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of MAPK14 protein]"	15963507
C093642	SB 203580	SB 203580 inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]	21635667
C093642	SB 203580	SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]	21635667
C093642	SB 203580	SB 203580 inhibits the reaction [Cadmium Chloride results in decreased expression of MAPK14 mRNA]	19757093
C093642	SB 203580	SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of MAPK14 protein]	20232314
C093642	SB 203580	SB 203580 inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]	15964311
C093642	SB 203580	SB 203580 inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK14 protein]	16864444
C093642	SB 203580	SB 203580 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK14 protein]	15631803
C093642	SB 203580	SB 203580 inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]	19767766
C093642	SB 203580	"SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"	21635667
C093642	SB 203580	SB 203580 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22226621
C093642	SB 203580	SB 203580 inhibits the reaction [Methotrexate results in increased phosphorylation of MAPK14 protein]	19100307
C093642	SB 203580	SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	14610070
C093642	SB 203580	SB 203580 results in decreased activity of MAPK14 protein	10998351\|1524277
C093642	SB 203580	SB 203580 affects the reaction [MAPK14 protein affects the reaction [sodium arsenite results in increased activity of MAPKAPK2 protein]]	10704466
C093642	SB 203580	SB 203580 results in decreased activity of MAPK14 protein	15585325
C093642	SB 203580	[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of CAV1 protein]	14984747
C093642	SB 203580	[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of PPARG protein alternative form]	14984747
C093642	SB 203580	SB 203580 inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]	17116659
C093642	SB 203580	SB 203580 inhibits the reaction [cupric chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	17234613
C093642	SB 203580	SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]	12487375
C093642	SB 203580	SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK14 protein]	8971075
C093642	SB 203580	SB 203580 inhibits the reaction [INS1 protein results in increased activity of MAPK14 protein]	8971075
C093642	SB 203580	SB 203580 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]	11709198
C093642	SB 203580	SB 203580 inhibits the reaction [sodium arsenite results in increased activity of MAPK14 protein]	8971075
C093642	SB 203580	"SB 203580 promotes the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"	16005925
C093642	SB 203580	SB 203580 results in decreased activity of MAPK14 protein	24376630
C093642	SB 203580	[SB 203580 results in decreased activity of MAPK14 protein] which results in decreased susceptibility to Doxorubicin	15936597
C093642	SB 203580	SB 203580 binds to MAPK14 protein	21905739
C093642	SB 203580	SB 203580 results in decreased activity of MAPK14	22226621
C093642	SB 203580	SB 203580 results in decreased activity of MAPK14 protein	10620750\|1101261
C406525	SB 239063	SB 239063 inhibits the reaction [prostaglandin E2 glyceryl ester results in increased phosphorylation of MAPK14 protein]	17539917
C499748	SCIO-469	SCIO-469 results in decreased phosphorylation of MAPK14 protein	16617327
C499748	SCIO-469	SCIO-469 results in decreased phosphorylation of MAPK14 protein	16617327
C499748	SCIO-469	SCIO-469 results in decreased activity of MAPK14 protein	16617327
D017632	Asbestos, Serpentine	"Asbestos, Serpentine results in increased phosphorylation of MAPK14 protein"	15882436
D012834	Silver	NFKBIA protein inhibits the reaction [Silver results in increased phosphorylation of MAPK14 protein]	22342292
D012834	Silver	Silver affects the expression of MAPK14 mRNA	22342292
D012834	Silver	Silver results in increased phosphorylation of MAPK14 protein	22342292
D019821	Simvastatin	Simvastatin results in increased phosphorylation of and results in increased activity of MAPK14 protein	17928392
D019821	Simvastatin	Simvastatin results in decreased expression of MAPK14 mRNA	16414398
C017947	sodium arsenite	sodium arsenite results in increased activity of MAPK14 protein	9288946
C017947	sodium arsenite	sodium arsenite results in increased activity of MAPK14 protein	22706169
C017947	sodium arsenite	sodium arsenite results in increased phosphorylation of and results in increased activity of MAPK14 protein	15504454
C017947	sodium arsenite	sodium arsenite results in increased phosphorylation of MAPK14 protein	21642427
C017947	sodium arsenite	"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]"	28757890
C017947	sodium arsenite	MAPK14 protein affects the reaction [sodium arsenite results in increased activity of MAPKAPK2 protein]	10704466
C017947	sodium arsenite	SB 203580 affects the reaction [MAPK14 protein affects the reaction [sodium arsenite results in increased activity of MAPKAPK2 protein]]	10704466
C017947	sodium arsenite	sodium arsenite results in increased expression of MAPK14 mRNA	28757890
C017947	sodium arsenite	sodium arsenite results in increased phosphorylation of MAPK14 protein	10704466
C017947	sodium arsenite	SB 203580 inhibits the reaction [sodium arsenite results in increased activity of MAPK14 protein]	8971075
C017947	sodium arsenite	sodium arsenite promotes the reaction [MAPK14 protein results in increased phosphorylation of BCL2L11 protein]	16818494
C017947	sodium arsenite	sodium arsenite results in increased activity of MAPK14 protein	8971075\|9288946
C017947	sodium arsenite	sodium arsenite results in increased expression of MAPK14 mRNA	24497207
C017947	sodium arsenite	sodium arsenite results in increased expression of MAPK14 protein	11446828
C017947	sodium arsenite	trans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]	24497207
C016104	sodium bichromate	sodium bichromate results in decreased expression of MAPK14 mRNA	22155349
D012965	Sodium Chloride	Sodium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein	15975986
D012967	Sodium Dodecyl Sulfate	Sodium Dodecyl Sulfate results in increased phosphorylation of MAPK14 protein	15737199
D012999	Soman	[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]	21971501
D012999	Soman	Soman results in increased phosphorylation of MAPK14 protein	21971501
C471405	sorafenib	sorafenib results in decreased expression of MAPK14 protein modified form	16985072
D013012	Sorbitol	Sorbitol results in increased phosphorylation of MAPK14 protein	15362974
D013311	Streptozocin	Streptozocin results in increased phosphorylation of MAPK14 protein	15232685
D013311	Streptozocin	Atorvastatin Calcium inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]	17589825
D013311	Streptozocin	Streptozocin results in increased phosphorylation of MAPK14 protein	17589825
C041711	St. Thomas' Hospital cardioplegic solution	St. Thomas' Hospital cardioplegic solution results in increased expression of MAPK14 mRNA	16214533
C041711	St. Thomas' Hospital cardioplegic solution	St. Thomas' Hospital cardioplegic solution results in increased expression of MAPK14 protein	16214533
C105686	SU 5402	SU 5402 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK14 protein]	15631803
D013395	Sucrose	Sucrose results in increased phosphorylation of and results in increased activity of MAPK14 protein	15975986
D000952	Antigens, Polyomavirus Transforming	"Antigens, Polyomavirus Transforming results in increased expression of MAPK14 mRNA"	26680231
C061133	tamibarotene	tamibarotene affects the expression of MAPK14 mRNA	15498508
D013629	Tamoxifen	alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein]	14645110
D013629	Tamoxifen	Tamoxifen results in increased activity of MAPK14 protein	14645110
D013657	Taurodeoxycholic Acid	Taurodeoxycholic Acid results in increased activity of MAPK14 protein	14762791
C084178	telmisartan	telmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22124178
C084178	telmisartan	telmisartan results in decreased phosphorylation of MAPK14 protein	19292980
D013739	Testosterone	Testosterone results in decreased expression of MAPK14 mRNA	21669218
D013739	Testosterone	Testosterone inhibits the reaction [Dexamethasone results in decreased expression of MAPK14 protein]	21094144
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in increased phosphorylation of MAPK14 protein	16198432
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of MAPK14 mRNA	20702593
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of MAPK14 mRNA	21570461
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of MAPK14 mRNA	25975270
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased phosphorylation of MAPK14 protein	23298284
D013750	Tetrachloroethylene	Tetrachloroethylene results in increased expression of MAPK14 mRNA	16010555
D013755	Tetradecanoylphorbol Acetate	SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]	14610070
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]	17309078
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]	14610070
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased activity of MAPK14 protein	12781867\|1594947
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein	16838270
D013755	Tetradecanoylphorbol Acetate	Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein]	15944151
D013792	Thalidomide	Thalidomide analog results in increased phosphorylation of MAPK14 protein	15858615
C056068	theaflavin	theaflavin results in decreased phosphorylation of MAPK14 protein	17499812
D013849	Thimerosal	Thimerosal results in decreased expression of MAPK14 mRNA	27188386
D013849	Thimerosal	Thimerosal results in increased phosphorylation of MAPK14 protein	15737199
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK14 mRNA	23830814
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK14 mRNA	23830814
D013853	Thioacetamide	Thioacetamide results in increased expression of MAPK14 protein	15953624
D008063	Thioctic Acid	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK14 mRNA	23830814
C009495	titanium dioxide	NFKBIA protein inhibits the reaction [titanium dioxide results in increased phosphorylation of MAPK14 protein]	22342292
C009495	titanium dioxide	titanium dioxide results in increased expression of MAPK14 mRNA	22342292
C009495	titanium dioxide	titanium dioxide results in increased phosphorylation of MAPK14 protein	22342292
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of MAPK14 mRNA	27404394
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of MAPK14 mRNA	16137721
C495469	trans-3-(4'-hydroxyphenyl)-2-propenoic acid	trans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]	24497207
D014212	Tretinoin	Imatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
D014212	Tretinoin	Tretinoin results in increased phosphorylation of and results in increased activity of MAPK14 protein	12032135
D014212	Tretinoin	wortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
D014212	Tretinoin	Tretinoin results in decreased expression of MAPK14 mRNA	15498508
D014212	Tretinoin	[Tretinoin results in increased activity of MAPK14 protein] which results in increased phosphorylation of and results in increased degradation of NCOA3 protein	16456540
D014212	Tretinoin	Tretinoin results in increased expression of MAPK14 mRNA	23724009
D014212	Tretinoin	Imatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
D014212	Tretinoin	Tretinoin results in decreased activity of MAPK14 protein	16424397
D014212	Tretinoin	Tretinoin results in increased phosphorylation of and results in increased activity of MAPK14 protein	12032135
D014212	Tretinoin	wortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
C011559	tributyltin	tributyltin results in increased expression of MAPK14 mRNA	26314263
D014241	Trichloroethylene	Trichloroethylene results in decreased expression of MAPK14 mRNA	19448997
C012589	trichostatin A	DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]]	21911040
C012589	trichostatin A	trichostatin A affects the expression of MAPK14 mRNA	28542535
C012589	trichostatin A	trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	21911040
D014268	Trifluoperazine	Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D014268	Trifluoperazine	Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
D014268	Trifluoperazine	Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]	21544200
C052920	trimethylarsine oxide	trimethylarsine oxide results in increased expression of MAPK14 mRNA	17481689
C001899	triptolide	"triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"	17507666
C057693	troglitazone	MAPK14 protein affects the reaction [troglitazone results in increased expression of GADD45A mRNA]	15064713
D014415	Tunicamycin	Tunicamycin results in decreased expression of MAPK14 mRNA	17127020
C101044	tyrphostin AG 1478	tyrphostin AG 1478 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]	11329622
C113580	U 0126	"U 0126 inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"	28087840
C113580	U 0126	U 0126 results in decreased activity of MAPK14 protein	10998351\|1459295
C113580	U 0126	"U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"	16005925
C113580	U 0126	U 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]	11709198
D014635	Valproic Acid	Valproic Acid affects the expression of MAPK14 mRNA	25979313
D014638	Vanadates	"Vanadates inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"	17507666
C034028	vanadyl sulfate	vanadyl sulfate results in decreased expression of MAPK14 mRNA	16330358
C111237	vorinostat	[Bortezomib co-treated with vorinostat] results in increased phosphorylation of MAPK14 protein	12893773
C009687	wortmannin	wortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
C009687	wortmannin	wortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]	12032135
C108830	Y 27632	Y 27632 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]	22226621
C031238	zinc sulfide	[cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK14 mRNA	22342292
C031238	zinc sulfide	[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein	22342292
C031238	zinc sulfide	NFKBIA protein inhibits the reaction [[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein]	22342292
D015054	Zymosan	Zymosan results in increased expression of MAPK14 protein modified form	19041413
D015054	Zymosan	Zymosan results in increased activity of MAPK14 protein	17984584

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004674	protein serine/threonine kinase activity	-	TAS	-
GO:0004707	MAP kinase activity	-	IBA	21873635
GO:0004707	MAP kinase activity	-	IDA	7997261 10330143 20932473
GO:0004708	MAP kinase kinase activity	-	TAS	10706854
GO:0005515	protein binding	-	IPI	9792677 10601328 11238443 11847341 16189514 16751104 17255097 17255949 17380123 17380128 18624398 20347885 20368287 20871633 20936779 21283629 21900206 21908610 21988832 22521293 23397142 23455922 23560844 23602568 25241761 25852190 26496610
GO:0005524	ATP binding	-	IEA	-
GO:0019899	enzyme binding	-	IPI	23483889
GO:0019903	protein phosphatase binding	-	IPI	10391943 21283629
GO:0048273	mitogen-activated protein kinase p38 binding	-	IPI	11035004
GO:0051525	NFAT protein binding	-	ISS	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000077	DNA damage checkpoint	-	IEA	-
GO:0000187	activation of MAPK activity	-	TAS	-
GO:0000902	cell morphogenesis	-	IEA	-
GO:0001502	cartilage condensation	-	IEA	-
GO:0001525	angiogenesis	-	IEA	-
GO:0001890	placenta development	-	IEA	-
GO:0002062	chondrocyte differentiation	-	IEA	-
GO:0002741	positive regulation of cytokine secretion involved in immune response	-	IEA	-
GO:0006006	glucose metabolic process	-	IEA	-
GO:0006351	transcription, DNA-templated	-	IEA	-
GO:0006357	regulation of transcription by RNA polymerase II	-	ISS	-
GO:0006915	apoptotic process	-	IEA	-
GO:0006935	chemotaxis	-	TAS	10706854
GO:0007165	signal transduction	-	TAS	10706854
GO:0007166	cell surface receptor signaling pathway	-	TAS	10706854
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	-	IEA	-
GO:0007519	skeletal muscle tissue development	-	IEA	-
GO:0010468	regulation of gene expression	-	IBA	21873635
GO:0010628	positive regulation of gene expression	-	IMP	25754930 26649771
GO:0010759	positive regulation of macrophage chemotaxis	-	IEA	-
GO:0010831	positive regulation of myotube differentiation	-	ISS	-
GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	-	IEA	-
GO:0018105	peptidyl-serine phosphorylation	-	ISS	-
GO:0019395	fatty acid oxidation	-	IEA	-
GO:0030278	regulation of ossification	-	IEA	-
GO:0030316	osteoclast differentiation	-	ISS	-
GO:0031281	positive regulation of cyclase activity	-	IMP	22027397
GO:0031663	lipopolysaccharide-mediated signaling pathway	-	IEA	-
GO:0032495	response to muramyl dipeptide	-	IEA	-
GO:0035556	intracellular signal transduction	-	IBA	21873635
GO:0035556	intracellular signal transduction	-	IDA	10838079
GO:0035924	cellular response to vascular endothelial growth factor stimulus	-	IMP	18440775
GO:0035994	response to muscle stretch	-	IEA	-
GO:0038066	p38MAPK cascade	-	ISS	-
GO:0042307	positive regulation of protein import into nucleus	-	IEA	-
GO:0042770	signal transduction in response to DNA damage	-	IMP	20160708
GO:0043312	neutrophil degranulation	-	TAS	-
GO:0043536	positive regulation of blood vessel endothelial cell migration	NOT	IMP	18440775
GO:0045648	positive regulation of erythrocyte differentiation	-	IMP	23483889
GO:0045663	positive regulation of myoblast differentiation	-	ISS	-
GO:0045944	positive regulation of transcription by RNA polymerase II	-	IEA	-
GO:0046326	positive regulation of glucose import	-	IEA	-
GO:0048010	vascular endothelial growth factor receptor signaling pathway	-	IMP	18440775
GO:0051146	striated muscle cell differentiation	-	IEA	-
GO:0051149	positive regulation of muscle cell differentiation	-	TAS	-
GO:0060045	positive regulation of cardiac muscle cell proliferation	-	IEA	-
GO:0070935	3'-UTR-mediated mRNA stabilization	-	TAS	20932473
GO:0071222	cellular response to lipopolysaccharide	-	IDA	23776175
GO:0071223	cellular response to lipoteichoic acid	-	IMP	26649771
GO:0071310	cellular response to organic substance	-	IBA	21873635
GO:0071356	cellular response to tumor necrosis factor	-	IEA	-
GO:0071479	cellular response to ionizing radiation	-	IMP	20160708
GO:0090090	negative regulation of canonical Wnt signaling pathway	-	IEA	-
GO:0090336	positive regulation of brown fat cell differentiation	-	IEA	-
GO:0090400	stress-induced premature senescence	-	IMP	20160708
GO:0098586	cellular response to virus	-	IMP	25754930
GO:1900015	regulation of cytokine production involved in inflammatory response	-	IDA	15251176
GO:1901741	positive regulation of myoblast fusion	-	ISS	-
GO:1901796	regulation of signal transduction by p53 class mediator	-	TAS	-
GO:1905050	positive regulation of metallopeptidase activity	-	IEA	-
GO:2000379	positive regulation of reactive oxygen species metabolic process	-	IMP	20160708
GO:2001184	positive regulation of interleukin-12 secretion	-	IMP	25754930

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000922	spindle pole	-	IEA	-
GO:0005576	extracellular region	-	TAS	-
GO:0005634	nucleus	-	IBA	21873635
GO:0005634	nucleus	-	ISS	-
GO:0005654	nucleoplasm	-	TAS	-
GO:0005737	cytoplasm	-	IBA	21873635
GO:0005737	cytoplasm	-	ISS	-
GO:0005739	mitochondrion	-	IEA	-
GO:0005829	cytosol	-	TAS	-
GO:0016607	nuclear speck	-	IDA	-
GO:0034774	secretory granule lumen	-	TAS	-
GO:1904813	ficolin-1-rich granule lumen	-	TAS	-

KEGG ID	KEGG Term
hsa04010	MAPK signaling pathway
hsa04370	VEGF signaling pathway
hsa04380	Osteoclast differentiation
hsa04620	Toll-like receptor signaling pathway
hsa04621	NOD-like receptor signaling pathway
hsa04622	RIG-I-like receptor signaling pathway
hsa04660	T cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04670	Leukocyte transendothelial migration
hsa04722	Neurotrophin signaling pathway
hsa04912	GnRH signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa05014	Amyotrophic lateral sclerosis (ALS)
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05131	Shigellosis
hsa05140	Leishmaniasis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05160	Hepatitis C

Reactome ID	Reactome Term	Evidence
R-HSA-109582	Hemostasis	TAS
R-HSA-1266738	Developmental Biology	TAS
R-HSA-1266738	Developmental Biology	IEA
R-HSA-1280215	Cytokine Signaling in Immune system	TAS
R-HSA-1592230	Mitochondrial biogenesis	IEA
R-HSA-162582	Signal Transduction	TAS
R-HSA-162582	Signal Transduction	IEA
R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	TAS
R-HSA-166058	MyD88:Mal cascade initiated on plasma membrane	TAS
R-HSA-166166	MyD88-independent TLR4 cascade	TAS
R-HSA-166520	Signaling by NTRKs	TAS
R-HSA-166520	Signaling by NTRKs	IEA
R-HSA-167044	Signalling to RAS	TAS
R-HSA-167044	Signalling to RAS	IEA
R-HSA-168138	Toll Like Receptor 9 (TLR9) Cascade	TAS
R-HSA-168142	Toll Like Receptor 10 (TLR10) Cascade	TAS
R-HSA-168164	Toll Like Receptor 3 (TLR3) Cascade	TAS
R-HSA-168176	Toll Like Receptor 5 (TLR5) Cascade	TAS
R-HSA-168179	Toll Like Receptor TLR1:TLR2 Cascade	TAS
R-HSA-168181	Toll Like Receptor 7/8 (TLR7/8) Cascade	TAS
R-HSA-168188	Toll Like Receptor TLR6:TLR2 Cascade	TAS
R-HSA-168249	Innate Immune System	TAS
R-HSA-168256	Immune System	TAS
R-HSA-168638	NOD1/2 Signaling Pathway	TAS
R-HSA-168643	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	TAS
R-HSA-168898	Toll-Like Receptors Cascades	TAS
R-HSA-171007	p38MAPK events	TAS
R-HSA-171007	p38MAPK events	IEA
R-HSA-181438	Toll Like Receptor 2 (TLR2) Cascade	TAS
R-HSA-1852241	Organelle biogenesis and maintenance	IEA
R-HSA-187037	Signaling by NTRK1 (TRKA)	TAS
R-HSA-187037	Signaling by NTRK1 (TRKA)	IEA
R-HSA-187687	Signalling to ERKs	TAS
R-HSA-187687	Signalling to ERKs	IEA
R-HSA-194138	Signaling by VEGF	TAS
R-HSA-198725	Nuclear Events (kinase and transcription factor activation)	TAS
R-HSA-198753	ERK/MAPK targets	TAS
R-HSA-212436	Generic Transcription Pathway	TAS
R-HSA-2151209	Activation of PPARGC1A (PGC-1alpha) by phosphorylation	IEA
R-HSA-2262752	Cellular responses to stress	TAS
R-HSA-2559580	Oxidative Stress Induced Senescence	TAS
R-HSA-2559583	Cellular Senescence	TAS
R-HSA-3700989	Transcriptional Regulation by TP53	TAS
R-HSA-373752	Netrin-1 signaling	TAS
R-HSA-375170	CDO in myogenesis	TAS
R-HSA-375170	CDO in myogenesis	IEA
R-HSA-376172	DSCAM interactions	TAS
R-HSA-392518	Signal amplification	TAS
R-HSA-418346	Platelet homeostasis	TAS
R-HSA-418592	ADP signalling through P2Y purinoceptor 1	TAS
R-HSA-422475	Axon guidance	TAS
R-HSA-432142	Platelet sensitization by LDL	TAS
R-HSA-4420097	VEGFA-VEGFR2 Pathway	TAS
R-HSA-448424	Interleukin-17 signaling	TAS
R-HSA-449147	Signaling by Interleukins	TAS
R-HSA-450282	MAPK targets/ Nuclear events mediated by MAP kinases	TAS
R-HSA-450294	MAP kinase activation	TAS
R-HSA-450302	activated TAK1 mediates p38 MAPK activation	TAS
R-HSA-450341	Activation of the AP-1 family of transcription factors	TAS
R-HSA-450531	Regulation of mRNA stability by proteins that bind AU-rich elements	IEA
R-HSA-450604	KSRP (KHSRP) binds and destabilizes mRNA	IEA
R-HSA-525793	Myogenesis	TAS
R-HSA-525793	Myogenesis	IEA
R-HSA-5633007	Regulation of TP53 Activity	TAS
R-HSA-6798695	Neutrophil degranulation	TAS
R-HSA-6804756	Regulation of TP53 Activity through Phosphorylation	TAS
R-HSA-73857	RNA Polymerase II Transcription	TAS
R-HSA-74160	Gene expression (Transcription)	TAS
R-HSA-76002	Platelet activation, signaling and aggregation	TAS
R-HSA-8953854	Metabolism of RNA	IEA
R-HSA-8953897	Cellular responses to external stimuli	TAS
R-HSA-9006934	Signaling by Receptor Tyrosine Kinases	TAS
R-HSA-9006934	Signaling by Receptor Tyrosine Kinases	IEA
R-HSA-937061	TRIF(TICAM1)-mediated TLR4 signaling	TAS
R-HSA-975138	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	TAS
R-HSA-975155	MyD88 dependent cascade initiated on endosome	TAS
R-HSA-975871	MyD88 cascade initiated on plasma membrane	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
22415779	p38 Mitogen-activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients. (2012 Oct 15)	Planchard D	Cancer
19661247	Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. (2009 Nov 1)	Deshmukh HS	Am J Respir Crit Care Med
25629224	MAPK genes interact with diet and lifestyle factors to alter risk of breast cancer: the Breast Cancer Health Disparities Study. (2015)	Slattery ML	Nutr Cancer
22199996	Tumor necrosis factor-related genes and colon and rectal cancer. (2011)	Slattery ML	Int J Mol Epidemiol Genet
28592245	In silico identification of potential key regulatory factors in smoking-induced lung cancer. (2017 Jun 7)	El-Aarag SA	BMC Med Genomics
17056606	Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs. (2007 Mar)	van Leeuwen DM	Carcinogenesis
23027623	MAP kinase genes and colon and rectal cancer. (2012 Dec)	Slattery ML	Carcinogenesis