Gene: MAPK14

1432
CSBP|CSBP1|CSBP2|CSPB1|EXIP|Mxi2|PRKM14|PRKM15|RK|SAPK2A|p38|p38ALPHA
mitogen-activated protein kinase 14
protein-coding
6p21.31
Ensembl:ENSG00000112062 MIM:600289 Vega:OTTHUMG00000159806 UniprotKB:Q16539
NC_000006.12
PubMed
ND
7   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.173e-1 (AD)  5.224e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FAM160B10.93
RALGAPB0.927
RNF1450.926
RANBP20.924
MIA30.922
RBBP50.922
KAT70.921
FOXJ30.92
UBP10.92
AP1G10.919

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.588
OR4F29-0.553
CTNNA3-0.302
S100A1-0.295
C5orf64-0.293
KLRB1-0.289
SOX3-0.286
HEY2-0.282
KLRC2-0.276
ASB4-0.276

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01254DasatinibSmall Molecule302962-49-8Approved|InvestigationalTarget
DB017614-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-PiperidineSmall MoleculeExperimentalTarget
DB01807N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)UreaSmall MoleculeExperimentalTarget
DB019481-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-OneSmall MoleculeExperimentalTarget
DB01953Inhibitor of P38 KinaseSmall Molecule-ExperimentalTarget
DB019886((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)PyrazineSmall MoleculeExperimentalTarget
DB021953-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]PyridineSmall MoleculeExperimentalTarget
DB022771-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-UreaSmall MoleculeExperimentalTarget
DB023523-(Benzyloxy)Pyridin-2-AmineSmall MoleculeExperimentalTarget
DB028731-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-OneSmall MoleculeExperimentalTarget
DB029844-[3-Methylsulfanylanilino]-6,7-DimethoxyquinazolineSmall MoleculeExperimentalTarget
DB030441-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-UreaSmall MoleculeExperimental|InvestigationalTarget
DB031102-ChlorophenolSmall MoleculeExperimentalTarget
DB039804-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)ImidazoleSmall MoleculeExperimentalTarget
DB04338SB220025Small MoleculeExperimentalTarget
DB046324-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDESmall MoleculeExperimentalTarget
DB04797TriazolopyridineSmall Molecule-ExperimentalTarget
DB05157KC706Small Molecule-InvestigationalTarget
DB05412TalmapimodSmall Molecule309913-83-5InvestigationalTarget
DB05470VX-702Small MoleculeInvestigationalTarget
DB068821-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylureaSmall MoleculeExperimentalTarget
DB06940N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamideSmall Molecule-ExperimentalTarget
DB06991N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamideSmall MoleculeExperimentalTarget
DB07138NeflamapimodSmall Molecule209410-46-8InvestigationalTarget
DB07307N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamideSmall MoleculeExperimentalTarget
DB074594-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDESmall MoleculeExperimentalTarget
DB076074-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINESmall MoleculeExperimentalTarget
DB07811N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamideSmall MoleculeExperimentalTarget
DB078294-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINESmall MoleculeExperimentalTarget
DB078324-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehydeSmall MoleculeExperimentalTarget
DB07833N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamideSmall MoleculeExperimentalTarget
DB07834N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamideSmall MoleculeExperimentalTarget
DB07835N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamideSmall MoleculeExperimentalTarget
DB07941PH-797804Small Molecule586379-66-0InvestigationalTarget
DB079422-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridineSmall MoleculeExperimentalTarget
DB079432-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanolSmall MoleculeExperimentalTarget
DB08064N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREASmall MoleculeExperimentalTarget
DB08068N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-Small MoleculeExperimentalTarget
DB080913-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDESmall MoleculeExperimentalTarget
DB080923-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamideSmall Molecule-ExperimentalTarget
DB080933-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINESmall MoleculeExperimentalTarget
DB080953-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREASmall MoleculeExperimentalTarget
DB080968-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUMSmall MoleculeExperimentalTarget
DB080972-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINESmall MoleculeExperimentalTarget
DB08242N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamideSmall MoleculeExperimentalTarget
DB08349N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamideSmall MoleculeExperimentalTarget
DB08351N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamideSmall MoleculeExperimentalTarget
DB083526-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amineSmall MoleculeExperimentalTarget
DB083952-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONESmall MoleculeExperimentalTarget
DB08423[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONESmall MoleculeExperimentalTarget
DB08424[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONESmall MoleculeExperimentalTarget
DB085214-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINESmall MoleculeExperimentalTarget
DB085224-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLESmall MoleculeExperimentalTarget
DB087303-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDESmall MoleculeExperimentalTarget
ID Drug Name Action PubMed
C49019111,11'-dideoxyverticilin"11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of MAPK14 protein"15963507
C49019111,11'-dideoxyverticilin"SB 203580 inhibits the reaction [11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of MAPK14 protein]"15963507
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"21544200
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased activity of MAPK14 protein]"21544200
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of MAPK14 mRNA"19162173
C5254681-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine1-(5-(4-chlorophenyl)-4-(4-pyridinyl)-1H-pyrazol-3-yl)-4-methylpiperazine results in decreased activity of MAPK14 protein20448081
C0233501-iodo-2,4-dinitrobenzene"1-iodo-2,4-dinitrobenzene results in increased phosphorylation of MAPK14 protein"19427879
C4470282,2',4,6-tetrachlorobiphenyl"MAPK14 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]"16120751
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAPK14 protein15964311
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased activity of MAPK14 protein15631803
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole results in decreased activity of MAPK14 protein14685156
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of MAPK14 protein]16000378
C4086042-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole results in decreased phosphorylation of and results in decreased activity of MAPK14 protein16000378
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of MAPK14 mRNA"20702593
C4843272'-benzoyloxycinnamaldehyde2'-benzoyloxycinnamaldehyde results in increased phosphorylation of MAPK14 protein14660655
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of MAPK14 mRNA]"19467301
C1087293,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]"17237268
C0354193,4-dihydroxybenzohydroxamic acid"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]"25843059
C4411283-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate"3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate affects the reaction [Dietary Fats affects the phosphorylation of MAPK14 protein]"28899902
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [MAPK14 protein modified form results in increased phosphorylation of and results in increased activity of ATF2 protein]9688607
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased susceptibility to MAPK14 protein modified form9688607
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased activity of MAPK14 protein10998351|1524942
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Dexamethasone affects the localization of MAPK14 protein modified form]20181797
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in increased expression of MAPK14 protein16046226
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole results in decreased activity of MAPK14 protein16046226
C522498(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine results in decreased activity of MAPK14 protein21449619
C1081234-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]"17116659
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein12684028
C0275764-hydroxy-2-nonenalAcetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]12684028
C0275764-hydroxy-2-nonenalalpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]12684028
C0275764-hydroxy-2-nonenalHydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]12684028
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of MAPK14 mRNA19191707
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein16322078
C0275764-hydroxy-2-nonenalresveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]16322078
C0123584-hydroxycyclophosphamide[afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of MAPK14 mRNA25833159
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of MAPK14 mRNA20829426
C5031195-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone results in increased phosphorylation of MAPK14 protein15831436
C0520266-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole"[6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole results in decreased phosphorylation of MAPK14 protein] which results in decreased expression of TOP2A protein"15753397
D000082AcetaminophenAcetaminophen results in decreased expression of MAPK14 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of MAPK14 mRNA17562736
D000109AcetylcholineMAPK14 protein affects the reaction [Acetylcholine results in increased activity of MAPKAPK2 protein]9288946
D000109AcetylcholineAcetylcholine results in increased phosphorylation of and results in increased activity of MAPK14 protein9688607
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]12684028
D000111AcetylcysteineAcetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]12684028
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]17237268
D000111AcetylcysteineAcetylcysteine inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]21635667
D000111AcetylcysteineAcetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]21635667
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]18703135
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"28087840
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]14729614
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D000111Acetylcysteine"Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"21635667
D000111AcetylcysteineAcetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK14 protein]15650392
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]18703135
D000171AcroleinAcrolein results in increased phosphorylation of MAPK14 protein17196791
D000171AcroleinAcrolein results in increased phosphorylation of MAPK14 protein11329622|1150470
D000171Acroleintyrphostin AG 1478 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]11329622
D000171AcroleinAcrolein results in increased phosphorylation of MAPK14 protein12487375
D000171Acrolein[Acrolein results in increased phosphorylation of MAPK14 protein] which results in increased phosphorylation of ATF2 protein12487375
D000171AcroleinSB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]12487375
C016601afimoxifeneMAPK14 results in decreased susceptibility to afimoxifene21233418
C016601afimoxifene[afimoxifene co-treated with 4-hydroxycyclophosphamide] affects the expression of MAPK14 mRNA25833159
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of MAPK14 mRNA"23195993
D000450AldosteroneMAPK14 protein affects the chemical synthesis of Aldosterone14592955
D019386AlendronateAlendronate affects the expression of MAPK14 mRNA16079270
D000493AllopurinolAllopurinol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D013196DihydrotestosteroneDihydrotestosterone results in increased expression of MAPK14 mRNA17023530
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]12684028
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [APP protein results in increased activity of MAPK14 protein]12684028
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein]14645110
C077990alvocidib[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK14 protein15634644
D004999AmifostineAmifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein]19010997
D006710HomocysteineAcetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766
D006710HomocysteineAtorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766|2001828
D006710Homocysteinediphenyleneiodonium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766
D006710HomocysteineHomocysteine results in increased phosphorylation of MAPK14 protein19767766|2001828
D006710HomocysteineNOX4 mutant form inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]20018284
D006710HomocysteineSB 203580 inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766
D006710HomocysteineAtorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]20305681
D006710HomocysteineHomocysteine results in increased phosphorylation of MAPK14 protein20305681
D000643Ammonium ChlorideAmmonium Chloride affects the expression of MAPK14 mRNA16483693
C023650anilineaniline results in increased phosphorylation of MAPK14 protein16169568|1842024
D000841AnisomycinAnisomycin results in increased phosphorylation of and results in increased activity of MAPK14 protein16364386
D000841AnisomycinAnisomycin results in increased phosphorylation of MAPK14 protein10704466|1603879
D000841AnisomycinMAPK14 protein affects the reaction [Anisomycin results in increased activity of MAPKAPK2 protein]10704466
D000841AnisomycinAnisomycin results in increased phosphorylation of and results in increased activity of MAPK14 protein15961565
D000968Antimycin AAntimycin A inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D016718Arachidonic AcidMAPK14 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]19540902
D016718Arachidonic AcidMAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]19540902
D016718Arachidonic AcidMAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]19540902
D016718Arachidonic Acid"MAPK14 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]"16120751
D001151ArsenicArsenic affects the methylation of MAPK14 gene25304211
C006632arsenic trioxide"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]"17237268
C006632arsenic trioxideAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]17237268
C006632arsenic trioxideAcetylcysteine inhibits the reaction [Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]14729614
C006632arsenic trioxide[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein17237268
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein12239215|1461007
C006632arsenic trioxideEmodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]14729614
C006632arsenic trioxideMAPK14 mutant form inhibits the reaction [arsenic trioxide affects the localization of BAX protein]18412143
C006632arsenic trioxideMAPK14 mutant form inhibits the reaction [arsenic trioxide results in increased phosphorylation of BCL2 protein]18412143
C006632arsenic trioxideMAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of EIF4E protein]18299328
C006632arsenic trioxideMAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MKNK1 protein]18299328
C006632arsenic trioxideMAPK14 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MKNK2 protein]18299328
C006632arsenic trioxideMAPK14 results in decreased susceptibility to arsenic trioxide16818652
C006632arsenic trioxidePPM1D mutant form promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]18482988
C006632arsenic trioxideSB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]14610070
C006632arsenic trioxideTetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]14610070
C006632arsenic trioxidearsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein16818652
C006632arsenic trioxideMAP2K3 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]16818652
C006632arsenic trioxideMAP2K6 protein promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]16818652
C006632arsenic trioxidearsenic trioxide inhibits the reaction [PPM1D protein results in decreased phosphorylation of MAPK14 protein]18482988
C015001arseniteMAPK14 mutant form inhibits the reaction [arsenite results in increased ubiquitination of and results in increased degradation of CCNB1 protein]17373649
C015001arseniteMAPK14 protein affects the reaction [arsenite promotes the reaction [EIF4E protein binds to EIF4G1 protein]]12781867
C015001arseniteMAPK14 protein mutant form inhibits the reaction [CGP 57380 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]12781867
C015001arseniteMAPK14 protein mutant form inhibits the reaction [SB 203580 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]12781867
C015001arsenitearsenite results in increased phosphorylation of MAPK14 protein17038550
D001194AsbestosAsbestos results in increased activity of MAPK14 protein10660835
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased expression of and results in decreased phosphorylation of MAPK14 protein"17191120
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased phosphorylation of and results in decreased activity of MAPK14 protein"17507666
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein"14962975|1750766
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased phosphorylation of MAPK14 protein"18314537
D017638Asbestos, Crocidolite"Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"17507666
D017638Asbestos, Crocidolite"MAPK14 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of DUSP6 protein]"18314537
D017638Asbestos, Crocidolite"SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein]"14962975
D017638Asbestos, Crocidolite"triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"17507666
D017638Asbestos, Crocidolite"Vanadates inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"17507666
D001205Ascorbic AcidAscorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]16407847
C022870asoxime chloride[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]21971501
D001241AspirinAspirin promotes the reaction [IL1A results in increased phosphorylation of MAPK14 protein]14742690
D001241AspirinAspirin results in increased phosphorylation of MAPK14 protein14742690
D001241AspirinIL1A promotes the reaction [Aspirin results in increased phosphorylation of MAPK14 protein]14742690
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766|2001828
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]20305681
D000069059Atorvastatin CalciumAtorvastatin Calcium inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]17589825
D001280AtrazineAtrazine results in increased expression of MAPK14 mRNA25929836
D001285Atropine[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]21971501
C012765bakuchiolbakuchiol results in increased phosphorylation of and results in increased activity of MAPK14 protein17292878
C030935benz(a)anthraceneAcetylcysteine inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]21635667
C030935benz(a)anthracenebenz(a)anthracene results in increased phosphorylation of MAPK14 protein21635667
C030935benz(a)anthraceneSB 203580 inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]21635667
D001548Benzalkonium CompoundsBenzalkonium Compounds results in increased phosphorylation of MAPK14 protein15737199
C017228benzo(a)pyrene 7,8-dihydrodiol"benzo(a)pyrene 7,8-dihydrodiol results in increased phosphorylation of MAPK14 protein"15698582
C072019benzo(a)pyrene diolepoxide Ibenzo(a)pyrene diolepoxide I results in increased phosphorylation of MAPK14 protein15698582
C022921benzo(k)fluorantheneAcetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]21635667
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein21635667
C022921benzo(k)fluorantheneSB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]21635667
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of MAPK14 mRNA20702593
D001564Benzo(a)pyreneBenzo(a)pyrene metabolite results in increased expression of MAPK14 mRNA26314263
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased phosphorylation of MAPK14 protein15698582
D001564Benzo(a)pyreneMAPK14 protein promotes the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]25233930
D004958EstradiolEstradiol results in increased activity of MAPK14 protein15955695
C099952bifenthrinbifenthrin affects the expression of MAPK14 mRNA26975043
C542674bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II)"MAPK14 protein promotes the reaction [bis((2-oxindol-3-ylimino)-2-(2-aminoethyl)pyridine-N,N')copper(II) results in increased expression of TP53 protein]"21548882
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]16407847
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK14 protein]15925026
C006780bisphenol Abisphenol A results in increased expression of MAPK14 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of MAPK14 mRNA26314263
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in decreased expression of MAPK14 mRNA17553608
D000069286Bortezomib[Bortezomib co-treated with Butyrates] results in increased phosphorylation of MAPK14 protein12893773
D000069286Bortezomib[Bortezomib co-treated with vorinostat] results in increased phosphorylation of MAPK14 protein12893773
D000069286BortezomibMAPK14 mutant form inhibits the reaction [Bortezomib results in increased cleavage of CASP3 protein]18790767
C439264bovine serum albumin-corticosterone conjugatebovine serum albumin-corticosterone conjugate results in increased phosphorylation of and results in increased activity of MAPK14 protein15961565
C032036bromobenzenebromobenzene analog results in increased phosphorylation of MAPK14 protein19427879
D016642BupropionBupropion results in increased phosphorylation of and results in increased activity of MAPK14 protein21354251
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased phosphorylation of MAPK14 protein17191120
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]18691550
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]18691550
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]18691550
D002083Butylated HydroxyanisoleButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]18691550
D002084Butylated HydroxytolueneButylated Hydroxytoluene results in increased expression of MAPK14 mRNA19925653
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of MAPK14 mRNA15336504
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of MAPK14 mRNA27509014
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased methylation of MAPK14 gene27509014
D020122tert-Butylhydroperoxide"4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]"17116659
D020122tert-ButylhydroperoxideSB 203580 inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]17116659
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein17116659
D002087Butyrates[Bortezomib co-treated with Butyrates] results in increased phosphorylation of MAPK14 protein12893773
D002087ButyratesButyrates results in increased phosphorylation of and results in increased activity of MAPK14 protein15978324
D002104CadmiumCadmium promotes the reaction [MAPK14 protein results in increased phosphorylation of HSP27 protein]17335952
D002104CadmiumCadmium results in increased phosphorylation of MAPK14 protein17335952
D002104CadmiumCadmium results in increased phosphorylation of MAPK14 protein20232314
D002104CadmiumSB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of MAPK14 protein]20232314
D002104Cadmium"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium results in increased activity of MAPK14 protein]"21544200
C028031cadmium acetatebisindolylmaleimide I inhibits the reaction [cadmium acetate results in increased phosphorylation of MAPK14 protein]15925026
C028031cadmium acetatecadmium acetate affects the expression of MAPK14 mRNA16249259
C028031cadmium acetatecadmium acetate results in increased phosphorylation of MAPK14 protein15925026
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"21544200
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]18703135
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of MAPK14 mRNA19757093
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK14 protein16264267|1870313
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D019256Cadmium ChlorideMAPK14 gene mutant form inhibits the reaction [Cadmium Chloride results in increased ubiquitination of and results in increased degradation of CDC20 protein]20054826
D019256Cadmium ChlorideMAPK14 mutant form inhibits the reaction [Cadmium Chloride results in increased ubiquitination of and results in increased degradation of CDC20 protein]20054826
D019256Cadmium Chloridesalubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]21809093
D019256Cadmium ChlorideSB 203580 inhibits the reaction [Cadmium Chloride results in decreased expression of MAPK14 mRNA]19757093
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK14 protein18348256
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D019256Cadmium Chloride[MAP2K4 co-treated with MAP2K7] affects the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]18348256
D019256Cadmium ChlorideMAP2K4 mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]18348256
D019256Cadmium ChlorideMAPK14 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]10874044
D019256Cadmium ChlorideMAPK14 mutant form inhibits the reaction [Cadmium Chloride results in increased expression of HSPA1A protein]18348256
D019256Cadmium ChlorideMAPK14 mutant form inhibits the reaction [MAP2K7 mutant form promotes the reaction [Cadmium Chloride results in increased expression of HSPA1A protein]]18348256
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK14 protein17027146
D019256Cadmium Chloride"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]"21544200
D019256Cadmium ChlorideAcetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]18703135
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein21544200
D019256Cadmium ChlorideCadmium Chloride results in increased phosphorylation of MAPK14 protein18703135|2193318
D019256Cadmium ChlorideCAMK2A mutant form inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]21933187
D019256Cadmium ChlorideEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D019256Cadmium ChlorideKN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]21933187
D019256Cadmium ChlorideTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D019256Cadmium ChlorideMAPK14 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D019256Cadmium ChlorideMAPK14 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D019256Cadmium ChlorideMAPK14 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]11709198
C058667cadmium selenide[cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK14 mRNA22342292
C058667cadmium selenide[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein22342292
C058667cadmium selenideNFKBIA protein inhibits the reaction [[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein]22342292
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA20360939
D000001Calcimycin2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Calcimycin results in increased phosphorylation of and results in increased activity of MAPK14 protein]16000378
D000001CalcimycinCalcimycin results in increased phosphorylation of and results in increased activity of MAPK14 protein16000378
D002118CalciumCalcium affects the expression of MAPK14 mRNA15913539
D002211CapsaicinCapsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein]21745629
D002220CarbamazepineCarbamazepine affects the expression of MAPK14 mRNA24752500
D002248Carbon MonoxideMAPK14 protein affects the reaction [BCL2A1 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]11880364
D002248Carbon MonoxideMAPK14 protein affects the reaction [BIRC3 protein inhibits the reaction [NFKBIA protein inhibits the reaction [[HMOX1 protein results in increased chemical synthesis of Carbon Monoxide] which results in decreased susceptibility to TNF protein]]]11880364
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased phosphorylation of MAPK14 protein17285312
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased phosphorylation of and results in increased activity of MAPK14 protein17334410
D002251Carbon TetrachlorideFR 167653 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]17334410
C043211carvedilolcarvedilol inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]16213474
D000068579Celecoxib[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK14 protein16463383
C469298CEP-11004CEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]17698565
C466997CGP 57380MAPK14 protein mutant form inhibits the reaction [CGP 57380 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]12781867
D002599ChalconeChalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22155221
D002726Chlorogenic AcidChlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein]15944151
D002746ChlorpromazineChlorpromazine analog results in decreased expression of MAPK14 mRNA15924885
D002784Cholesterol[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA25833014
D002784Cholesterolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA]25833014
C529269cholix toxin, Vibrio cholerae"Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"28087840
C529269cholix toxin, Vibrio cholerae"cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein"28087840
C529269cholix toxin, Vibrio cholerae"U 0126 inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"28087840
C074702chromium hexavalent ionchromium hexavalent ion results in increased phosphorylation of MAPK14 protein17045426
C039671ciglitazone[ciglitazone binds to PPARG protein alternative form] which results in increased expression of MAPK14 mRNA16197558
C012843cinnamic aldehydecinnamic aldehyde results in increased phosphorylation of and results in increased activity of MAPK14 protein15964311
C012843cinnamic aldehydepyrazolanthrone inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]15964311
C012843cinnamic aldehydeSB 203580 inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]15964311
C012843cinnamic aldehydecinnamic aldehyde results in decreased phosphorylation of MAPK14 protein17486422
D003022ClotrimazoleMAPK14 promotes the reaction [Clotrimazole results in increased expression of ABCC3 mRNA]27507784
D003024ClozapineClozapine affects the expression of MAPK14 mRNA15860345
C018021cobaltous chloridecobaltous chloride results in increased expression of MAPK14 mRNA26314263
C018021cobaltous chlorideMAPK14 mutant form inhibits the reaction [cobaltous chloride results in increased expression of NOS2 protein]23624824
C018021cobaltous chlorideMAPK14 mutant form inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]23624824
D003042CocaineCocaine results in increased activity of MAPK14 protein18952886
D003042CocaineMAPK14 protein affects the susceptibility to Cocaine10620750
C075384coniferaldehydeMAPK14 mutant form inhibits the reaction [coniferaldehyde affects the localization of and results in increased phosphorylation of NFE2L2 protein]26275128
C075384coniferaldehydeMAPK14 mutant form inhibits the reaction [coniferaldehyde results in increased expression of HMOX1 protein]26275128
D019327Copper SulfateCopper Sulfate affects the expression of MAPK14 mRNA19549813
C067957corticosterone-21-hemisuccinatecorticosterone-21-hemisuccinate results in increased phosphorylation of and results in increased activity of MAPK14 protein15961565
C477330CP-654577CP-654577 results in decreased expression of MAPK14 protein12907618
C494620CPS 11CPS 11 results in increased phosphorylation of MAPK14 protein15858615
C494622CPS 49CPS 49 results in increased phosphorylation of MAPK14 protein15858615
C029892cupric chloridecupric chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein17234613
C029892cupric chlorideSB 203580 inhibits the reaction [cupric chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]17234613
D003474CurcuminCurcumin inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased phosphorylation of MAPK14 protein]17151092
D003474CurcuminMAPK14 protein affects the reaction [Curcumin results in increased expression of HMOX1 protein]18357586
C057862cyanoginosin LRcyanoginosin LR results in increased phosphorylation of and results in increased activity of MAPK14 protein22000993
C057862cyanoginosin LRcyanoginosin LR results in increased phosphorylation of MAPK14 protein22000993
D003513Cycloheximide"Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"17507666
D003520Cyclophosphamide[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA16322899
D003520CyclophosphamideCyclophosphamide affects the expression of MAPK14 mRNA18246545
D003520CyclophosphamideCyclophosphamide results in decreased expression of MAPK14 mRNA18246545
D003545Cysteine[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein11709198
D003545CysteineSB 203580 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]11709198
D003545CysteineU 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]11709198
D003545CysteineMAPK14 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D003545CysteineMAPK14 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D003545CysteineMAPK14 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]11709198
D000069439DasatinibDasatinib binds to MAPK14 protein18180381
D003634DDTDDT results in increased phosphorylation of MAPK14 protein14604893
C029415deacylcortivazoldeacylcortivazol promotes the reaction [MAPK14 protein results in increased phosphorylation of NR3C1 protein]15817653
C029415deacylcortivazoldeacylcortivazol results in increased phosphorylation of and results in increased activity of MAPK14 protein15817653
C007262deoxynivalenoldeoxynivalenol results in increased expression of MAPK14 mRNA20702593
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of and results in increased activity of MAPK14 protein16364386
C007262deoxynivalenoldeoxynivalenol results in increased phosphorylation of MAPK14 protein15976193
D003891DesipramineDesipramine results in increased activity of MAPK14 protein18986328
D003907DexamethasoneDexamethasone inhibits the reaction [Mitomycin results in increased activity of and results in increased phosphorylation of MAPK14 protein]20002897
D003907DexamethasoneDexamethasone promotes the reaction [MAPK14 protein results in increased phosphorylation of NR3C1 protein]15817653
D003907DexamethasoneDexamethasone results in increased activity of MAPK14 protein11012613
D003907DexamethasoneDexamethasone results in increased phosphorylation of and results in increased activity of MAPK14 protein15817653
D003907DexamethasoneDexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]16880258
D003907DexamethasoneDexamethasone results in increased expression of MAPK14 mRNA22733784
D003907DexamethasoneDUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]]16880258
D003907Dexamethasone[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of CAV1 protein]14984747
D003907Dexamethasone[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of PPARG protein alternative form]14984747
D003907Dexamethasone4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Dexamethasone affects the localization of MAPK14 protein modified form]20181797
D003907DexamethasoneDexamethasone affects the localization of [MAPK14 protein modified form binds to FOXO1 protein]20181797
D003907DexamethasoneDexamethasone promotes the reaction [MAPK14 protein modified form binds to FOXO1 protein]20181797
D003907DexamethasoneDexamethasone results in decreased expression of MAPK14 protein21094144
D003907DexamethasoneDexamethasone results in increased phosphorylation of and affects the localization of MAPK14 protein20181797
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of MAPK14 protein]21094144
D016190CarboplatinCarboplatin results in decreased expression of MAPK14 mRNA18172885
D003975Diazepam[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]21971501
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased phosphorylation of and results in increased activity of MAPK14 protein"16005925
C041517dibenzo(a,l)pyrene"pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"16005925
C041517dibenzo(a,l)pyrene"SB 203580 promotes the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"16005925
C041517dibenzo(a,l)pyrene"U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"16005925
D002945CisplatinCisplatin results in increased phosphorylation of MAPK14 protein22006019
D004008DiclofenacDiclofenac affects the expression of MAPK14 mRNA24752500
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of MAPK14 mRNA]"19467301
D004041Dietary Fats"3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate affects the reaction [Dietary Fats affects the phosphorylation of MAPK14 protein]"28899902
D004041Dietary FatsDietary Fats affects the phosphorylation of MAPK14 protein28899902
D004041Dietary FatsDietary Fats results in increased expression of MAPK14 mRNA19467301
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]]18691550
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]]18691550
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]]18691550
D004052DiethylnitrosamineButylated Hydroxyanisole inhibits the reaction [MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of BAG3 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP4A12A mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DUSP4 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of HSPB1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of IKBKG mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of IRAK2 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of PLA2G16 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TRIB1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased abundance of Reactive Oxygen Species]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGT mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CARD10 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CASP9 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCND1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CCNH mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of CITED2 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of DDIT3 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EFNA1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FGF1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of FMO3 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45B mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of HGF mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1A protein]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL1B mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IL6 protein]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of IRF1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of JUN mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAP2K4 protein]18691550
D004052DiethylnitrosamineMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAP2K7 protein]18691550
D004052DiethylnitrosamineMAPK14 protein promotes the reaction [Diethylnitrosamine results in increased expression of HMOX1 protein]18691550
D004052DiethylnitrosamineMAPK14 protein promotes the reaction [Diethylnitrosamine results in increased expression of HSBP1 mRNA]18691550
D004052DiethylnitrosamineMAPK14 protein promotes the reaction [Diethylnitrosamine results in increased expression of HSBP1 protein]18691550
D004052DiethylnitrosamineMAPK14 protein results in decreased susceptibility to Diethylnitrosamine18691550
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of MAPK14 mRNA20360939
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK14 mRNA23830814
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK14 mRNA23830814
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of MAPK14 mRNA20360939
D004052Diethylnitrosamine[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of MAPK14 mRNA18977376
D002117CalcitriolCalcitriol results in increased activity of MAPK14 protein19748465
D002117CalcitriolCAMP mutant form inhibits the reaction [Calcitriol results in increased activity of MAPK14 protein]19748465
D002117Calcitriol[CAMP results in increased activity of MAPK14] affects the reaction [Calcitriol results in increased expression of ATG5 mRNA]19748465
D002117Calcitriol[CAMP results in increased activity of MAPK14] affects the reaction [Calcitriol results in increased expression of BECN1 mRNA]19748465
D002117Calcitriol[Calcitriol co-treated with TGFB1 protein] results in increased phosphorylation of MAPK14 protein16598785
D002117CalcitriolCalcitriol results in increased phosphorylation of MAPK14 protein16598785
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased phosphorylation of MAPK14 protein15737199
D004139DinitrofluorobenzeneDinitrofluorobenzene results in increased phosphorylation of MAPK14 protein19427879
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766
D004317DoxorubicinDoxorubicin affects the activity of MAPK14 protein15870702
D004317Doxorubicin[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA16322899
D004317DoxorubicinDoxorubicin promotes the reaction [MAPK14 protein results in decreased expression of BCL2L1 protein]16843435
D004317DoxorubicinDoxorubicin promotes the reaction [MAPK14 protein results in decreased phosphorylation of BAD protein]16843435
D004317DoxorubicinDoxorubicin results in increased phosphorylation of and results in increased activity of MAPK14 protein15494689|1684343
D004317DoxorubicinDoxorubicin results in increased phosphorylation of MAPK14 protein15557793
D004317Doxorubicincarvedilol inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]16213474
D004317DoxorubicinDoxorubicin results in increased phosphorylation of MAPK14 protein15767673|1621347
D004317DoxorubicinRazoxane inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]16213474
D004317Doxorubicin[SB 203580 results in decreased activity of MAPK14 protein] which results in decreased susceptibility to Doxorubicin15936597
D004318DoxycyclineDoxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein]18089841
C060327dracorhodindracorhodin analog results in increased phosphorylation of MAPK14 protein15684474|1686444
C060327dracorhodinSB 203580 inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK14 protein]16864444
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased phosphorylation of MAPK14 protein"15894585
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]"17996413
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]"28757890
D004391DustDust results in decreased expression of MAPK14 mRNA17805423
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D004533Egtazic AcidEgtazic Acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D004610Ellagic AcidEllagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein]27965107
D004640EmetineEmetine results in increased phosphorylation of and results in increased activity of MAPK14 protein16364386
D004640EmetineMAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP2 protein]26332055
D004640EmetineMAPK14 mutant form inhibits the reaction [Emetine results in decreased activity of MMP9 protein]26332055
D004640EmetineMAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK1 protein]26332055
D004640EmetineMAPK14 mutant form inhibits the reaction [Emetine results in decreased phosphorylation of MAPK3 protein]26332055
D004642EmodinAcetylcysteine inhibits the reaction [Emodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]14729614
D004642EmodinEmodin promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]14729614
D004726EndosulfanEndosulfan results in increased phosphorylation of and results in increased activity of MAPK14 protein22146149
C044101endotoxin, Escherichia coli"endotoxin, Escherichia coli results in increased phosphorylation of MAPK14 protein"16919916
C044101endotoxin, Escherichia coli"Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of MAPK14 protein]"16919916
D004785Environmental PollutantsEnvironmental Pollutants results in decreased expression of MAPK14 mRNA12655031
C045651epigallocatechin gallate[epigallocatechin gallate co-treated with Celecoxib] results in increased activity of MAPK14 protein16463383
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MAPK14 mRNA22079256
D004875Ergosterol[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA25833014
D004875Ergosterolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA]25833014
C007628esculetin[esculetin co-treated with Paclitaxel] results in decreased expression of MAPK14 protein16051289
C007628esculetinesculetin results in decreased phosphorylation of and results in decreased activity of MAPK14 protein16051289
D004976Ethacrynic AcidEthacrynic Acid results in decreased expression of MAPK14 protein14556662
D000431EthanolMAPK14 protein promotes the reaction [Ethanol results in increased expression of and results in increased phosphorylation of TP53 protein]27270636
D000431EthanolMAPK14 protein promotes the reaction [Ethanol results in increased expression of CASP3 protein modified form]27270636
D000431EthanolMAPK14 protein results in increased susceptibility to Ethanol27270636
D000431EthanolEthanol affects the expression of MAPK14 mRNA11772933
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of MAPK14 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of MAPK14 mRNA16079270
D005015Ethoxyquin[Ethoxyquin results in increased expression of PRDX1 protein] which results in increased phosphorylation of MAPK14 protein16880205
C456800ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate[alvocidib co-treated with ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate] results in increased phosphorylation of and results in increased activity of MAPK14 protein15634644
C013531ferric ammonium citrateferric ammonium citrate results in increased phosphorylation of MAPK14 protein17191120
D005473FluoxetineFluoxetine results in increased phosphorylation of MAPK14 protein16413968
D005480FlurbiprofenMAPK14 protein promotes the reaction [Flurbiprofen results in increased expression of GDF15 protein]21097678
D005480FlurbiprofenMAPK14 protein promotes the reaction [Flurbiprofen results in increased expression of NGFR protein]18056468
D005480FlurbiprofenMAPK14 protein promotes the reaction [Flurbiprofen results in increased phosphorylation of EIF4E protein]18056468
D005557FormaldehydeFormaldehyde results in increased phosphorylation of MAPK14 protein15737199
D009240N-Formylmethionine Leucyl-PhenylalanineN-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of and results in increased activity of MAPK14 protein17406807
D009240N-Formylmethionine Leucyl-PhenylalanineOmeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein]17406807
D009240N-Formylmethionine Leucyl-PhenylalanineN-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein16621998
C104334FR 167653FR 167653 inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]17334410
D037741FullerenesFullerenes analog results in increased expression of MAPK14 mRNA22342292
D037741FullerenesFullerenes analog results in increased phosphorylation of MAPK14 protein22342292
D037741FullerenesNFKBIA protein inhibits the reaction [Fullerenes analog results in increased phosphorylation of MAPK14 protein]22342292
D019833GenisteinGenistein results in decreased expression of MAPK14 mRNA21048042
D005839GentamicinsGentamicins results in increased expression of MAPK14 mRNA22061828
D005839GentamicinsGentamicins results in increased expression of MAPK14 protein16751989
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]19626664
D005947GlucoseCAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]17309078
D005947GlucoseGlucose deficiency results in increased activity of MAPK14 protein17309078
D005947GlucoseGlucose results in decreased phosphorylation of MAPK14 protein20200188
D005947GlucoseMAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of KRT20 protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of VIM protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in decreased expression of CDH1 protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 mRNA]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in decreased expression of KRT20 protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in increased expression of ACTA2 protein]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in increased expression of SNAI1 mRNA]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in increased expression of VIM mRNA]21829520
D005947GlucoseMAPK14 protein promotes the reaction [Glucose results in increased secretion of FN1 protein]21829520
D005947GlucoseTetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]17309078
D005947GlucoseGlucose promotes the reaction [EIF2AK2 protein results in increased activity of MAPK14 protein]18973755
D005947Glucose[resveratrol co-treated with Glucose] results in decreased expression of MAPK14 mRNA24659233
D006220HaloperidolHaloperidol affects the expression of MAPK14 mRNA15860345
D006221HalothaneHalothane results in decreased expression of MAPK14 protein24598351
D006221HalothaneHalothane results in increased expression of MAPK14 mRNA24598351
D006427HeminHemin inhibits the reaction [IL18 protein results in increased expression of MAPK14 protein]18215737
D006581HexachlorobenzeneHexachlorobenzene affects the expression of MAPK14 mRNA15159207
D017313FenretinideAscorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]16407847
D017313Fenretinidebisindolylmaleimide I inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein]16407847
D017313FenretinideFenretinide results in increased activity of MAPK14 protein16407847
D017313FenretinideFenretinide results in increased phosphorylation of MAPK14 protein16407847
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]12684028
D006861Hydrogen PeroxideAcetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D006861Hydrogen PeroxideAllopurinol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D006861Hydrogen Peroxidealpha-Tocopherol inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]12684028
D006861Hydrogen PeroxideAntimycin A inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D006861Hydrogen PeroxideHydrogen Peroxide promotes the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]12684028
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of and results in increased activity of MAPK14 protein12684028
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK14 protein15650392
D006861Hydrogen PeroxideRotenone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK14 protein19010997
D006861Hydrogen PeroxidePRDX1 protein promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]16880205
D006861Hydrogen PeroxideHydrogen Peroxide results in increased activity of MAPK14 protein15574683|8971075
D006861Hydrogen PeroxideHydrogen Peroxide results in increased phosphorylation of MAPK14 protein16284289
D006861Hydrogen PeroxideProgesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]16284289
D006861Hydrogen PeroxideSB 203580 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK14 protein]8971075
D007052IbuprofenMAPK14 protein promotes the reaction [Ibuprofen results in increased expression of GDF15 protein]21097678
D007052IbuprofenMAPK14 protein promotes the reaction [Ibuprofen results in increased expression of NGFR protein]18056468
D007052IbuprofenMAPK14 protein promotes the reaction [Ibuprofen results in increased phosphorylation of EIF4E protein]18056468
D000068877Imatinib MesylateImatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
D000068877Imatinib MesylateImatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
C041508indeno(1,2,3-cd)pyrene"Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"21635667
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein"21635667
C041508indeno(1,2,3-cd)pyrene"SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"21635667
C514526indole-5-carboxamideindole-5-carboxamide results in decreased activity of MAPK14 protein15363871
D007545IsoproterenolDoxycycline inhibits the reaction [Isoproterenol results in increased phosphorylation of MAPK14 protein]18089841
D007545IsoproterenolIsoproterenol results in increased phosphorylation of MAPK14 protein18089841
C063587juzentaihotojuzentaihoto promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]15778123
D007657Ketone BodiesKetone Bodies results in increased expression of MAPK14 mRNA16807920
C072105KN 93KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]21933187
C508710L-826266L-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK14 protein]16644903
C008261lead acetatelead acetate affects the expression of MAPK1424293362
C008281limonenelimonene results in increased expression of MAPK14 mRNA12815608
C440499lipopolysaccharide, Escherichia coli O111 B4"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]"19549798
C440499lipopolysaccharide, Escherichia coli O111 B4"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]"19549798
C440499lipopolysaccharide, Escherichia coli O111 B4"MAPK14 protein affects the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]"19549798
C440499lipopolysaccharide, Escherichia coli O111 B4"MAPK14 protein affects the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]"19549798
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of MAPK14 protein modified form19041413
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of MAPK14 protein22053092
D008070LipopolysaccharidesARHGEF2 mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22226621
D008070LipopolysaccharidesCEP-11004 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]17698565
D008070LipopolysaccharidesDUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]]21911040
D008070LipopolysaccharidesLipopolysaccharides results in decreased activity of MAPK14 protein14997032
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of MAPK14 protein21911040|2212417
D008070LipopolysaccharidesRHOA mutant form inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22226621
D008070LipopolysaccharidesSB 203580 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22226621
D008070Lipopolysaccharidestelmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22124178
D008070Lipopolysaccharidestrichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]21911040
D008070LipopolysaccharidesY 27632 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22226621
D008070Lipopolysaccharides"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]"25843059
D008070LipopolysaccharidesAmifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein]19010997
D008070LipopolysaccharidesChalcone analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22155221
D008070LipopolysaccharidesDexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]16880258
D008070Lipopolysaccharides"Drugs, Chinese Herbal inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]"17996413
D008070LipopolysaccharidesDUSP1 protein promotes the reaction [Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein]]16880258
D008070LipopolysaccharidesGSTP1 protein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]16023107
D008070Lipopolysaccharidesjuzentaihoto promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]15778123
D008070LipopolysaccharidesLipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein19010997
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of MAPK14 mRNA25843059
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK14 protein16880258|1799641
D008070LipopolysaccharidesLipopolysaccharides results in increased phosphorylation of MAPK14 protein10704466|1577812
D008070Lipopolysaccharideslycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22155741
D008070LipopolysaccharidesMAPK14 protein promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]15795323
D008070Lipopolysaccharidesmethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]15933225
C015329lycopenelycopene results in decreased expression of MAPK14 protein17337101
C015329lycopenelycopene results in increased expression of MAPK14 mRNA16886892
C015330lycorinelycorine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22155741
C065861malvidinmalvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein15964118
D008345ManganeseManganese results in decreased phosphorylation of MAPK14 protein17043766
C025340manganese chloridemanganese chloride results in increased phosphorylation of MAPK14 protein15737199
C025340manganese chloridemanganese chloride results in increased expression of MAPK14 mRNA17467022
D000069997Mastic Resin[Mastic Resin co-treated with Diethylnitrosamine] results in decreased expression of MAPK14 mRNA18977376
D008627Mercuric ChlorideMercuric Chloride results in increased phosphorylation of MAPK14 protein15585369
D008701MethapyrileneMethapyrilene results in decreased expression of MAPK14 mRNA16393664
D008715Methionine[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein11709198
D008715MethionineSB 203580 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]11709198
D008715MethionineU 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]11709198
D008715MethionineMAPK14 promotes the reaction [MAPK1 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D008715MethionineMAPK14 promotes the reaction [MAPK3 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]]11709198
D008715MethionineMAPK14 results in increased susceptibility to [Methionine deficiency co-treated with Cysteine deficiency co-treated with Cadmium Chloride]11709198
D008727MethotrexateMethotrexate results in decreased expression of MAPK14 mRNA19100307
D008727MethotrexateMethotrexate results in increased phosphorylation of MAPK14 protein19100307
D008727MethotrexateSB 203580 inhibits the reaction [Methotrexate results in increased phosphorylation of MAPK14 protein]19100307
C587228methyl 3-hydroxyimino-11-oxoolean-12-en-28-oatemethyl 3-hydroxyimino-11-oxoolean-12-en-28-oate results in increased expression of and results in increased phosphorylation of MAPK14 protein24291674
C014659methyl(acetoxymethyl)nitrosaminemethyl(acetoxymethyl)nitrosamine results in increased phosphorylation of and results in increased activity of MAPK14 protein12693035
C008435methyldithiocarbamatemethyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]15933225
C030957methylmercury IImethylmercury II results in increased expression of MAPK14 mRNA26314263
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of MAPK14 mRNA"20188158
D008769MethylnitronitrosoguanidineMethylnitronitrosoguanidine results in increased phosphorylation of MAPK14 protein22001597
D008770MethylnitrosoureaMethylnitrosourea results in increased phosphorylation of and results in increased activity of MAPK14 protein12693035
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased phosphorylation of MAPK14 protein22019741
D016685MitomycinDexamethasone inhibits the reaction [Mitomycin results in increased activity of and results in increased phosphorylation of MAPK14 protein]20002897
D016685MitomycinMitomycin results in increased activity of and results in increased phosphorylation of MAPK14 protein20002897
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of MAPK14 mRNA20024957
D009020MorphineMorphine results in increased expression of MAPK14 protein23056601
D009151Mustard GasMAPK14 mutant form inhibits the reaction [Mustard Gas results in increased expression of CXCL8 protein]20143454
D009151Mustard GasMAPK14 mutant form inhibits the reaction [Mustard Gas results in increased expression of IL6 protein]20143454
D009151Mustard GasMAPK14 mutant form inhibits the reaction [Mustard Gas results in increased expression of TNF protein]20143454
D009151Mustard GasMAPK14 protein affects the reaction [Mustard Gas results in increased expression of CXCL8 mRNA]23851002
D009151Mustard GasMAPK14 protein affects the reaction [Mustard Gas results in increased expression of IL6 mRNA]23851002
D009151Mustard GasMAPK14 protein affects the reaction [Mustard Gas results in increased expression of TNF mRNA]23851002
D009151Mustard GasMAPK14 protein affects the reaction [Mustard Gas results in increased secretion of CXCL8 protein]23851002
D009151Mustard GasMAPK14 protein affects the reaction [Mustard Gas results in increased secretion of IL1B protein]23851002
D009151Mustard GasMAPK14 protein affects the reaction [Mustard Gas results in increased secretion of IL6 protein]23851002
D009151Mustard GasMAPK14 protein affects the susceptibility to Mustard Gas23851002
D009151Mustard GasMustard Gas results in increased expression of MAPK14 mRNA15674844
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased phosphorylation of MAPK14 protein"20800606
D009287NaphthyridinesNaphthyridines analog affects the activity of MAPK14 protein21999461
C017096n-butoxyethanoln-butoxyethanol results in decreased expression of MAPK14 mRNA19812364
D009532NickelNickel results in decreased expression of MAPK14 mRNA23195993
C022838nickel chloridenickel chloride results in increased phosphorylation of MAPK14 protein15737199
D009605NitrosomethylurethaneNitrosomethylurethane results in increased phosphorylation of and results in increased activity of MAPK14 protein12693035
C404397NSC 680410NSC 680410 results in increased phosphorylation of MAPK14 protein14647418
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A inhibits the reaction [CDK1 protein binds to CCNB1 protein]]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CCNB1 protein]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDC25C protein]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDC25C protein modified form]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDK1 protein]22230261
C025589ochratoxin AMAPK14 protein promotes the reaction [ochratoxin A results in decreased expression of CDK1 protein modified form]22230261
C025589ochratoxin AMAPK14 protein results in increased susceptibility to ochratoxin A22230261
C025589ochratoxin Aochratoxin A metabolite results in increased expression of MAPK14 mRNA26314263
C025589ochratoxin Aochratoxin A results in increased expression of MAPK14 mRNA26314263
C031492octanoic acid[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of CAV1 protein]14984747
C031492octanoic acid[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of PPARG protein alternative form]14984747
D009828Oleanolic AcidOleanolic Acid analog results in decreased phosphorylation of MAPK14 protein26612655
D009853OmeprazoleOmeprazole inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK14 protein]17406807
C016340o,p'-DDT"MAPK14 protein promotes the reaction [o,p'-DDT results in increased activity of NOTCH1 protein]"18791200
D017239Paclitaxel[esculetin co-treated with Paclitaxel] results in decreased expression of MAPK14 protein16051289
D019308Palmitic AcidCapsaicin inhibits the reaction [Palmitic Acid results in increased phosphorylation of MAPK14 protein]21745629
D019308Palmitic AcidPalmitic Acid results in increased phosphorylation of MAPK14 protein21745629
D010269Paraquat"Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of MAPK14 protein]"16919916
D010269ParaquatParaquat results in increased phosphorylation of MAPK14 protein16797015|1691991
D010269Paraquat[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK14 protein24376630
D010269ParaquatParaquat results in increased phosphorylation of MAPK14 protein17324951|1799788
D010416PentachlorophenolPentachlorophenol results in increased expression of MAPK14 mRNA23892564
D010426Pentosan Sulfuric PolyesterPentosan Sulfuric Polyester results in increased expression of MAPK14 mRNA28973697
C101816perfluoro-n-nonanoic acidperfluoro-n-nonanoic acid affects the expression of MAPK14 mRNA19196829
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of MAPK14 protein28126411
C569762PF 03715455PF 03715455 binds to and results in decreased activity of MAPK14 protein21888439
D015232DinoprostoneDinoprostone results in increased activity of MAPK14 protein16644903
D015232DinoprostoneL-826266 inhibits the reaction [Dinoprostone results in increased activity of MAPK14 protein]16644903
D015232DinoprostoneDinoprostone results in increased phosphorylation of MAPK14 protein18030065
D010634PhenobarbitalPhenobarbital results in decreased expression of MAPK14 mRNA12807726
D010656PhenylephrinePhenylephrine results in increased phosphorylation of MAPK14 protein15757502
C003117phosaloneEllagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein]27965107
C003117phosalonephosalone results in increased expression of MAPK14 protein27965107
C012491phytosphingosine"3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoquinolinone inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]"17237268
C012491phytosphingosineAcetylcysteine inhibits the reaction [[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]17237268
C012491phytosphingosine[arsenic trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein17237268
C121565pifithrinpifithrin results in increased phosphorylation of MAPK14 protein16061640
C121565pifithrin"pifithrin inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"16005925
D010936Plant ExtractsPlant Extracts results in increased expression of MAPK14 mRNA23557933
D028321Plant PreparationsPlant Preparations results in increased expression of MAPK14 mRNA24973489
D011134PolysaccharidesPolysaccharides results in increased phosphorylation of MAPK14 protein15894585
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MAPK14 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of MAPK14 mRNA22079256
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of MAPK14 mRNA19162173
D011374ProgesteroneProgesterone promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]16284289
C518978prostaglandin E2 glyceryl esterprostaglandin E2 glyceryl ester results in increased phosphorylation of MAPK14 protein17539917
C518978prostaglandin E2 glyceryl esterSB 239063 inhibits the reaction [prostaglandin E2 glyceryl ester results in increased phosphorylation of MAPK14 protein]17539917
C107773pterostilbene"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of NOS2 protein]]"19549798
C107773pterostilbene"MAPK14 protein affects the reaction [pterostilbene inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of PTGS2 protein]]"19549798
C034912puag-haadpuag-haad results in increased expression of MAPK14 mRNA28780155
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]15964311
C432165pyrazolanthronepyrazolanthrone results in decreased phosphorylation of MAPK14 protein16046226
C432165pyrazolanthronepyrazolanthrone results in increased expression of MAPK14 protein16046226
D011720PyrazolesPyrazoles analog results in decreased activity of MAPK14 protein12534346
D011743PyrimidinesPyrimidines analog results in decreased activity of MAPK14 protein12534346
D011794QuercetinQuercetin results in increased expression of MAPK14 protein modified form22197970
D011794QuercetinMAPK14 protein promotes the reaction [Quercetin promotes the reaction [NR1H3 protein binds to ABCA1 promoter]]22711909
D011794QuercetinMAPK14 protein promotes the reaction [Quercetin promotes the reaction [SP1 protein binds to ABCA1 promoter]]22711909
D011794QuercetinMAPK14 protein promotes the reaction [Quercetin results in increased expression of ABCA1 mRNA]22711909
D011794QuercetinMAPK14 protein promotes the reaction [Quercetin results in increased expression of ABCA1 protein]22711909
D011799QuinazolinesQuinazolines binds to and results in decreased activity of MAPK14 protein18817365
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride affects the expression of MAPK14 mRNA16079270
D011929RazoxaneRazoxane inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein]16213474
D017382Reactive Oxygen SpeciesReactive Oxygen Species results in increased activity of MAPK14 protein17237268
D017382Reactive Oxygen SpeciesMAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased abundance of Reactive Oxygen Species]18691550
D017382Reactive Oxygen Species[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK14 protein24376630
C059514resveratrolresveratrol results in decreased expression of MAPK14 protein18089832
C059514resveratrol[resveratrol co-treated with Glucose] results in decreased expression of MAPK14 mRNA24659233
C059514resveratrolresveratrol inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of and results in increased activity of MAPK14 protein]16322078
C059514resveratrolresveratrol affects the expression of MAPK14 mRNA15748624
C059514resveratrolresveratrol inhibits the reaction [[Cholesterol co-treated with Ergosterol] results in increased expression of MAPK14 mRNA]25833014
C009166retinol acetateretinol acetate results in increased expression of MAPK14 mRNA16772331
D012402RotenoneRotenone inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]15650392
D012402RotenoneRotenone results in increased phosphorylation of and results in increased activity of MAPK14 protein14976342
D012402RotenoneRotenone results in increased phosphorylation of MAPK14 protein17324951|1977756
C085746rottlerinrottlerin results in decreased phosphorylation of MAPK14 protein15949478
C085746rottlerinrottlerin results in decreased phosphorylation of MAPK14 protein15949478
C010327salinomycinsalinomycin results in decreased expression of MAPK14 mRNA19682730
C496827salubrinalsalubrinal inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]21809093
C093642SB 203580SB 203580 results in decreased activity of MAPK14 protein15659807
C093642SB 203580MAPK14 protein mutant form inhibits the reaction [SB 203580 inhibits the reaction [arsenite results in increased phosphorylation of EIF4E protein]]12781867
C093642SB 203580"SB 203580 inhibits the reaction [11,11'-dideoxyverticilin results in increased expression of and results in increased phosphorylation of MAPK14 protein]"15963507
C093642SB 203580SB 203580 inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]21635667
C093642SB 203580SB 203580 inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]21635667
C093642SB 203580SB 203580 inhibits the reaction [Cadmium Chloride results in decreased expression of MAPK14 mRNA]19757093
C093642SB 203580SB 203580 inhibits the reaction [Cadmium results in increased phosphorylation of MAPK14 protein]20232314
C093642SB 203580SB 203580 inhibits the reaction [cinnamic aldehyde results in increased phosphorylation of MAPK14 protein]15964311
C093642SB 203580SB 203580 inhibits the reaction [dracorhodin analog results in increased phosphorylation of MAPK14 protein]16864444
C093642SB 203580SB 203580 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK14 protein]15631803
C093642SB 203580SB 203580 inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]19767766
C093642SB 203580"SB 203580 inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]"21635667
C093642SB 203580SB 203580 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22226621
C093642SB 203580SB 203580 inhibits the reaction [Methotrexate results in increased phosphorylation of MAPK14 protein]19100307
C093642SB 203580SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]14610070
C093642SB 203580SB 203580 results in decreased activity of MAPK14 protein10998351|1524277
C093642SB 203580SB 203580 affects the reaction [MAPK14 protein affects the reaction [sodium arsenite results in increased activity of MAPKAPK2 protein]]10704466
C093642SB 203580SB 203580 results in decreased activity of MAPK14 protein15585325
C093642SB 203580[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of CAV1 protein]14984747
C093642SB 203580[SB 203580 results in decreased activity of MAPK14 protein] inhibits the reaction [[octanoic acid co-treated with Dexamethasone] results in increased expression of PPARG protein alternative form]14984747
C093642SB 203580SB 203580 inhibits the reaction [tert-Butylhydroperoxide results in increased phosphorylation of MAPK14 protein]17116659
C093642SB 203580SB 203580 inhibits the reaction [cupric chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]17234613
C093642SB 203580SB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]12487375
C093642SB 203580SB 203580 inhibits the reaction [Hydrogen Peroxide results in increased activity of MAPK14 protein]8971075
C093642SB 203580SB 203580 inhibits the reaction [INS1 protein results in increased activity of MAPK14 protein]8971075
C093642SB 203580SB 203580 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]11709198
C093642SB 203580SB 203580 inhibits the reaction [sodium arsenite results in increased activity of MAPK14 protein]8971075
C093642SB 203580"SB 203580 promotes the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"16005925
C093642SB 203580SB 203580 results in decreased activity of MAPK14 protein24376630
C093642SB 203580[SB 203580 results in decreased activity of MAPK14 protein] which results in decreased susceptibility to Doxorubicin15936597
C093642SB 203580SB 203580 binds to MAPK14 protein21905739
C093642SB 203580SB 203580 results in decreased activity of MAPK1422226621
C093642SB 203580SB 203580 results in decreased activity of MAPK14 protein10620750|1101261
C406525SB 239063SB 239063 inhibits the reaction [prostaglandin E2 glyceryl ester results in increased phosphorylation of MAPK14 protein]17539917
C499748SCIO-469SCIO-469 results in decreased phosphorylation of MAPK14 protein16617327
C499748SCIO-469SCIO-469 results in decreased phosphorylation of MAPK14 protein16617327
C499748SCIO-469SCIO-469 results in decreased activity of MAPK14 protein16617327
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased phosphorylation of MAPK14 protein"15882436
D012834SilverNFKBIA protein inhibits the reaction [Silver results in increased phosphorylation of MAPK14 protein]22342292
D012834SilverSilver affects the expression of MAPK14 mRNA22342292
D012834SilverSilver results in increased phosphorylation of MAPK14 protein22342292
D019821SimvastatinSimvastatin results in increased phosphorylation of and results in increased activity of MAPK14 protein17928392
D019821SimvastatinSimvastatin results in decreased expression of MAPK14 mRNA16414398
C017947sodium arsenitesodium arsenite results in increased activity of MAPK14 protein9288946
C017947sodium arsenitesodium arsenite results in increased activity of MAPK14 protein22706169
C017947sodium arsenitesodium arsenite results in increased phosphorylation of and results in increased activity of MAPK14 protein15504454
C017947sodium arsenitesodium arsenite results in increased phosphorylation of MAPK14 protein21642427
C017947sodium arsenite"Drugs, Chinese Herbal inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]"28757890
C017947sodium arseniteMAPK14 protein affects the reaction [sodium arsenite results in increased activity of MAPKAPK2 protein]10704466
C017947sodium arseniteSB 203580 affects the reaction [MAPK14 protein affects the reaction [sodium arsenite results in increased activity of MAPKAPK2 protein]]10704466
C017947sodium arsenitesodium arsenite results in increased expression of MAPK14 mRNA28757890
C017947sodium arsenitesodium arsenite results in increased phosphorylation of MAPK14 protein10704466
C017947sodium arseniteSB 203580 inhibits the reaction [sodium arsenite results in increased activity of MAPK14 protein]8971075
C017947sodium arsenitesodium arsenite promotes the reaction [MAPK14 protein results in increased phosphorylation of BCL2L11 protein]16818494
C017947sodium arsenitesodium arsenite results in increased activity of MAPK14 protein8971075|9288946
C017947sodium arsenitesodium arsenite results in increased expression of MAPK14 mRNA24497207
C017947sodium arsenitesodium arsenite results in increased expression of MAPK14 protein11446828
C017947sodium arsenitetrans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]24497207
C016104sodium bichromatesodium bichromate results in decreased expression of MAPK14 mRNA22155349
D012965Sodium ChlorideSodium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein15975986
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in increased phosphorylation of MAPK14 protein15737199
D012999Soman[asoxime chloride co-treated with Atropine co-treated with Diazepam] affects the reaction [Soman results in increased phosphorylation of MAPK14 protein]21971501
D012999SomanSoman results in increased phosphorylation of MAPK14 protein21971501
C471405sorafenibsorafenib results in decreased expression of MAPK14 protein modified form16985072
D013012SorbitolSorbitol results in increased phosphorylation of MAPK14 protein15362974
D013311StreptozocinStreptozocin results in increased phosphorylation of MAPK14 protein15232685
D013311StreptozocinAtorvastatin Calcium inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein]17589825
D013311StreptozocinStreptozocin results in increased phosphorylation of MAPK14 protein17589825
C041711St. Thomas' Hospital cardioplegic solutionSt. Thomas' Hospital cardioplegic solution results in increased expression of MAPK14 mRNA16214533
C041711St. Thomas' Hospital cardioplegic solutionSt. Thomas' Hospital cardioplegic solution results in increased expression of MAPK14 protein16214533
C105686SU 5402SU 5402 inhibits the reaction [FGF2 protein results in increased phosphorylation of MAPK14 protein]15631803
D013395SucroseSucrose results in increased phosphorylation of and results in increased activity of MAPK14 protein15975986
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in increased expression of MAPK14 mRNA"26680231
C061133tamibarotenetamibarotene affects the expression of MAPK14 mRNA15498508
D013629Tamoxifenalpha-Tocopherol inhibits the reaction [Tamoxifen results in increased activity of MAPK14 protein]14645110
D013629TamoxifenTamoxifen results in increased activity of MAPK14 protein14645110
D013657Taurodeoxycholic AcidTaurodeoxycholic Acid results in increased activity of MAPK14 protein14762791
C084178telmisartantelmisartan inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22124178
C084178telmisartantelmisartan results in decreased phosphorylation of MAPK14 protein19292980
D013739TestosteroneTestosterone results in decreased expression of MAPK14 mRNA21669218
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of MAPK14 protein]21094144
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased phosphorylation of MAPK14 protein16198432
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MAPK14 mRNA20702593
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of MAPK14 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of MAPK14 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased phosphorylation of MAPK14 protein23298284
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of MAPK14 mRNA16010555
D013755Tetradecanoylphorbol AcetateSB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]14610070
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]17309078
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]14610070
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased activity of MAPK14 protein12781867|1594947
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein16838270
D013755Tetradecanoylphorbol AcetateChlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein]15944151
D013792ThalidomideThalidomide analog results in increased phosphorylation of MAPK14 protein15858615
C056068theaflavintheaflavin results in decreased phosphorylation of MAPK14 protein17499812
D013849ThimerosalThimerosal results in decreased expression of MAPK14 mRNA27188386
D013849ThimerosalThimerosal results in increased phosphorylation of MAPK14 protein15737199
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK14 mRNA23830814
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of MAPK14 mRNA23830814
D013853ThioacetamideThioacetamide results in increased expression of MAPK14 protein15953624
D008063Thioctic Acid[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of MAPK14 mRNA23830814
C009495titanium dioxideNFKBIA protein inhibits the reaction [titanium dioxide results in increased phosphorylation of MAPK14 protein]22342292
C009495titanium dioxidetitanium dioxide results in increased expression of MAPK14 mRNA22342292
C009495titanium dioxidetitanium dioxide results in increased phosphorylation of MAPK14 protein22342292
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of MAPK14 mRNA27404394
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of MAPK14 mRNA16137721
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid inhibits the reaction [sodium arsenite results in increased expression of MAPK14 mRNA]24497207
D014212TretinoinImatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
D014212TretinoinTretinoin results in increased phosphorylation of and results in increased activity of MAPK14 protein12032135
D014212Tretinoinwortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
D014212TretinoinTretinoin results in decreased expression of MAPK14 mRNA15498508
D014212Tretinoin[Tretinoin results in increased activity of MAPK14 protein] which results in increased phosphorylation of and results in increased degradation of NCOA3 protein16456540
D014212TretinoinTretinoin results in increased expression of MAPK14 mRNA23724009
D014212TretinoinImatinib Mesylate inhibits the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
D014212TretinoinTretinoin results in decreased activity of MAPK14 protein16424397
D014212TretinoinTretinoin results in increased phosphorylation of and results in increased activity of MAPK14 protein12032135
D014212Tretinoinwortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
C011559tributyltintributyltin results in increased expression of MAPK14 mRNA26314263
D014241TrichloroethyleneTrichloroethylene results in decreased expression of MAPK14 mRNA19448997
C012589trichostatin ADUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]]21911040
C012589trichostatin Atrichostatin A affects the expression of MAPK14 mRNA28542535
C012589trichostatin Atrichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]21911040
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
D014268TrifluoperazineTrifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein]21544200
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of MAPK14 mRNA17481689
C001899triptolide"triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"17507666
C057693troglitazoneMAPK14 protein affects the reaction [troglitazone results in increased expression of GADD45A mRNA]15064713
D014415TunicamycinTunicamycin results in decreased expression of MAPK14 mRNA17127020
C101044tyrphostin AG 1478tyrphostin AG 1478 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]11329622
C113580U 0126"U 0126 inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]"28087840
C113580U 0126U 0126 results in decreased activity of MAPK14 protein10998351|1459295
C113580U 0126"U 0126 inhibits the reaction [dibenzo(a,l)pyrene results in increased phosphorylation of MAPK14 protein]"16005925
C113580U 0126U 0126 inhibits the reaction [[Methionine deficiency co-treated with Cysteine deficiency] results in increased activity of MAPK14 protein]11709198
D014635Valproic AcidValproic Acid affects the expression of MAPK14 mRNA25979313
D014638Vanadates"Vanadates inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]"17507666
C034028vanadyl sulfatevanadyl sulfate results in decreased expression of MAPK14 mRNA16330358
C111237vorinostat[Bortezomib co-treated with vorinostat] results in increased phosphorylation of MAPK14 protein12893773
C009687wortmanninwortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
C009687wortmanninwortmannin promotes the reaction [Tretinoin results in increased phosphorylation of MAPK14 protein]12032135
C108830Y 27632Y 27632 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein]22226621
C031238zinc sulfide[cadmium selenide co-treated with zinc sulfide] results in increased expression of MAPK14 mRNA22342292
C031238zinc sulfide[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein22342292
C031238zinc sulfideNFKBIA protein inhibits the reaction [[cadmium selenide co-treated with zinc sulfide] results in increased phosphorylation of MAPK14 protein]22342292
D015054ZymosanZymosan results in increased expression of MAPK14 protein modified form19041413
D015054ZymosanZymosan results in increased activity of MAPK14 protein17984584

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004674protein serine/threonine kinase activity-TAS-  
GO:0004707MAP kinase activity-IBA21873635  
GO:0004707MAP kinase activity-IDA7997261  10330143  20932473  
GO:0004708MAP kinase kinase activity-TAS10706854  
GO:0005515protein binding-IPI9792677  10601328  11238443  11847341  16189514  16751104  
17255097  17255949  17380123  17380128  18624398  20347885  
20368287  20871633  20936779  21283629  21900206  21908610  
21988832  22521293  23397142  23455922  23560844  23602568  
25241761  25852190  26496610  
GO:0005524ATP binding-IEA-  
GO:0019899enzyme binding-IPI23483889  
GO:0019903protein phosphatase binding-IPI10391943  21283629  
GO:0048273mitogen-activated protein kinase p38 binding-IPI11035004  
GO:0051525NFAT protein binding-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000077DNA damage checkpoint-IEA-  
GO:0000187activation of MAPK activity-TAS-  
GO:0000902cell morphogenesis-IEA-  
GO:0001502cartilage condensation-IEA-  
GO:0001525angiogenesis-IEA-  
GO:0001890placenta development-IEA-  
GO:0002062chondrocyte differentiation-IEA-  
GO:0002741positive regulation of cytokine secretion involved in immune response-IEA-  
GO:0006006glucose metabolic process-IEA-  
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-ISS-  
GO:0006915apoptotic process-IEA-  
GO:0006935chemotaxis-TAS10706854  
GO:0007165signal transduction-TAS10706854  
GO:0007166cell surface receptor signaling pathway-TAS10706854  
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway-IEA-  
GO:0007519skeletal muscle tissue development-IEA-  
GO:0010468regulation of gene expression-IBA21873635  
GO:0010628positive regulation of gene expression-IMP25754930  26649771  
GO:0010759positive regulation of macrophage chemotaxis-IEA-  
GO:0010831positive regulation of myotube differentiation-ISS-  
GO:0014835myoblast differentiation involved in skeletal muscle regeneration-IEA-  
GO:0018105peptidyl-serine phosphorylation-ISS-  
GO:0019395fatty acid oxidation-IEA-  
GO:0030278regulation of ossification-IEA-  
GO:0030316osteoclast differentiation-ISS-  
GO:0031281positive regulation of cyclase activity-IMP22027397  
GO:0031663lipopolysaccharide-mediated signaling pathway-IEA-  
GO:0032495response to muramyl dipeptide-IEA-  
GO:0035556intracellular signal transduction-IBA21873635  
GO:0035556intracellular signal transduction-IDA10838079  
GO:0035924cellular response to vascular endothelial growth factor stimulus-IMP18440775  
GO:0035994response to muscle stretch-IEA-  
GO:0038066p38MAPK cascade-ISS-  
GO:0042307positive regulation of protein import into nucleus-IEA-  
GO:0042770signal transduction in response to DNA damage-IMP20160708  
GO:0043312neutrophil degranulation-TAS-  
GO:0043536positive regulation of blood vessel endothelial cell migrationNOTIMP18440775  
GO:0045648positive regulation of erythrocyte differentiation-IMP23483889  
GO:0045663positive regulation of myoblast differentiation-ISS-  
GO:0045944positive regulation of transcription by RNA polymerase II-IEA-  
GO:0046326positive regulation of glucose import-IEA-  
GO:0048010vascular endothelial growth factor receptor signaling pathway-IMP18440775  
GO:0051146striated muscle cell differentiation-IEA-  
GO:0051149positive regulation of muscle cell differentiation-TAS-  
GO:0060045positive regulation of cardiac muscle cell proliferation-IEA-  
GO:00709353'-UTR-mediated mRNA stabilization-TAS20932473  
GO:0071222cellular response to lipopolysaccharide-IDA23776175  
GO:0071223cellular response to lipoteichoic acid-IMP26649771  
GO:0071310cellular response to organic substance-IBA21873635  
GO:0071356cellular response to tumor necrosis factor-IEA-  
GO:0071479cellular response to ionizing radiation-IMP20160708  
GO:0090090negative regulation of canonical Wnt signaling pathway-IEA-  
GO:0090336positive regulation of brown fat cell differentiation-IEA-  
GO:0090400stress-induced premature senescence-IMP20160708  
GO:0098586cellular response to virus-IMP25754930  
GO:1900015regulation of cytokine production involved in inflammatory response-IDA15251176  
GO:1901741positive regulation of myoblast fusion-ISS-  
GO:1901796regulation of signal transduction by p53 class mediator-TAS-  
GO:1905050positive regulation of metallopeptidase activity-IEA-  
GO:2000379positive regulation of reactive oxygen species metabolic process-IMP20160708  
GO:2001184positive regulation of interleukin-12 secretion-IMP25754930  
GO ID GO Term Qualifier Evidence PubMed
GO:0000922spindle pole-IEA-  
GO:0005576extracellular region-TAS-  
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-ISS-  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IBA21873635  
GO:0005737cytoplasm-ISS-  
GO:0005739mitochondrion-IEA-  
GO:0005829cytosol-TAS-  
GO:0016607nuclear speck-IDA-  
GO:0034774secretory granule lumen-TAS-  
GO:1904813ficolin-1-rich granule lumen-TAS-  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04370VEGF signaling pathway
hsa04380Osteoclast differentiation
hsa04620Toll-like receptor signaling pathway
hsa04621NOD-like receptor signaling pathway
hsa04622RIG-I-like receptor signaling pathway
hsa04660T cell receptor signaling pathway
hsa04664Fc epsilon RI signaling pathway
hsa04670Leukocyte transendothelial migration
hsa04722Neurotrophin signaling pathway
hsa04912GnRH signaling pathway
hsa04914Progesterone-mediated oocyte maturation
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa05131Shigellosis
hsa05140Leishmaniasis
hsa05142Chagas disease (American trypanosomiasis)
hsa05145Toxoplasmosis
hsa05160Hepatitis C
Reactome ID Reactome Term Evidence
R-HSA-109582HemostasisTAS
R-HSA-1266738Developmental BiologyTAS
R-HSA-1266738Developmental BiologyIEA
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-1592230Mitochondrial biogenesisIEA
R-HSA-162582Signal TransductionTAS
R-HSA-162582Signal TransductionIEA
R-HSA-166016Toll Like Receptor 4 (TLR4) CascadeTAS
R-HSA-166058MyD88:Mal cascade initiated on plasma membraneTAS
R-HSA-166166MyD88-independent TLR4 cascade TAS
R-HSA-166520Signaling by NTRKsTAS
R-HSA-166520Signaling by NTRKsIEA
R-HSA-167044Signalling to RASTAS
R-HSA-167044Signalling to RASIEA
R-HSA-168138Toll Like Receptor 9 (TLR9) CascadeTAS
R-HSA-168142Toll Like Receptor 10 (TLR10) CascadeTAS
R-HSA-168164Toll Like Receptor 3 (TLR3) CascadeTAS
R-HSA-168176Toll Like Receptor 5 (TLR5) CascadeTAS
R-HSA-168179Toll Like Receptor TLR1:TLR2 CascadeTAS
R-HSA-168181Toll Like Receptor 7/8 (TLR7/8) CascadeTAS
R-HSA-168188Toll Like Receptor TLR6:TLR2 CascadeTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-168638NOD1/2 Signaling PathwayTAS
R-HSA-168643Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathwaysTAS
R-HSA-168898Toll-Like Receptors CascadesTAS
R-HSA-171007p38MAPK eventsTAS
R-HSA-171007p38MAPK eventsIEA
R-HSA-181438Toll Like Receptor 2 (TLR2) CascadeTAS
R-HSA-1852241Organelle biogenesis and maintenanceIEA
R-HSA-187037Signaling by NTRK1 (TRKA)TAS
R-HSA-187037Signaling by NTRK1 (TRKA)IEA
R-HSA-187687Signalling to ERKsTAS
R-HSA-187687Signalling to ERKsIEA
R-HSA-194138Signaling by VEGFTAS
R-HSA-198725Nuclear Events (kinase and transcription factor activation)TAS
R-HSA-198753ERK/MAPK targetsTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-2151209Activation of PPARGC1A (PGC-1alpha) by phosphorylationIEA
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2559580Oxidative Stress Induced SenescenceTAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-373752Netrin-1 signalingTAS
R-HSA-375170CDO in myogenesisTAS
R-HSA-375170CDO in myogenesisIEA
R-HSA-376172DSCAM interactionsTAS
R-HSA-392518Signal amplificationTAS
R-HSA-418346Platelet homeostasisTAS
R-HSA-418592ADP signalling through P2Y purinoceptor 1TAS
R-HSA-422475Axon guidanceTAS
R-HSA-432142Platelet sensitization by LDLTAS
R-HSA-4420097VEGFA-VEGFR2 PathwayTAS
R-HSA-448424Interleukin-17 signalingTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-450282MAPK targets/ Nuclear events mediated by MAP kinasesTAS
R-HSA-450294MAP kinase activationTAS
R-HSA-450302activated TAK1 mediates p38 MAPK activationTAS
R-HSA-450341Activation of the AP-1 family of transcription factorsTAS
R-HSA-450531Regulation of mRNA stability by proteins that bind AU-rich elementsIEA
R-HSA-450604KSRP (KHSRP) binds and destabilizes mRNAIEA
R-HSA-525793MyogenesisTAS
R-HSA-525793MyogenesisIEA
R-HSA-5633007Regulation of TP53 ActivityTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-6804756Regulation of TP53 Activity through PhosphorylationTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-76002Platelet activation, signaling and aggregationTAS
R-HSA-8953854Metabolism of RNAIEA
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesTAS
R-HSA-9006934Signaling by Receptor Tyrosine KinasesIEA
R-HSA-937061TRIF(TICAM1)-mediated TLR4 signaling TAS
R-HSA-975138TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activationTAS
R-HSA-975155MyD88 dependent cascade initiated on endosomeTAS
R-HSA-975871MyD88 cascade initiated on plasma membraneTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
22415779p38 Mitogen-activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients. (2012 Oct 15)Planchard DCancer
19661247Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. (2009 Nov 1)Deshmukh HSAm J Respir Crit Care Med
25629224MAPK genes interact with diet and lifestyle factors to alter risk of breast cancer: the Breast Cancer Health Disparities Study. (2015)Slattery MLNutr Cancer
22199996Tumor necrosis factor-related genes and colon and rectal cancer. (2011)Slattery MLInt J Mol Epidemiol Genet
28592245In silico identification of potential key regulatory factors in smoking-induced lung cancer. (2017 Jun 7)El-Aarag SABMC Med Genomics
17056606Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs. (2007 Mar)van Leeuwen DMCarcinogenesis
23027623MAP kinase genes and colon and rectal cancer. (2012 Dec)Slattery MLCarcinogenesis