Gene: CSF3

1440
C17orf33|CSF3OS|GCSF
colony stimulating factor 3
protein-coding
17q21.1
Ensembl:ENSG00000108342 MIM:138970 Vega:OTTHUMG00000133247 UniprotKB:P09919
NC_000017.11
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.231e-1 (AD)  6.235e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SELE0.869
CXCL10.826
ICAM10.749
IL60.715
ZC3H12A0.705
RNF1220.693
ARID5A0.688
MAFF0.684
SOCS30.681
CISH0.679

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HRASLS-0.356
KCNMB2-0.354
CNTN6-0.346
NXPH1-0.345
GPR85-0.337
STAR-0.335
IL34-0.331
MBLAC2-0.329
ZNF223-0.325
FBXO16-0.325

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CSF3 mRNA19933214
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CSF3 mRNA"25614096
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CSF3 mRNA"19114083
C0038982-anisidine2-anisidine affects the expression of CSF3 mRNA28089782
C0127962-butenal2-butenal results in decreased expression of CSF3 mRNA20471460
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CSF3 mRNA"28351761
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CSF3 protein"29216392
C0354193,4-dihydroxybenzohydroxamic acid"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]"25843059
C0354193,4-dihydroxybenzohydroxamic acid"3,4-dihydroxybenzohydroxamic acid results in decreased expression of CSF3 mRNA"25843059
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of CSF3 mRNA19191707
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of CSF3 mRNA19191707
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of CSF3 protein19191707
C0030017-ketocholesterol7-ketocholesterol results in increased expression of CSF3 protein24895526
C0030017-ketocholesterolresveratrol inhibits the reaction [7-ketocholesterol results in increased expression of CSF3 protein]24895526
C496492abrineabrine results in increased expression of CSF3 mRNA22595364
D000082AcetaminophenAcetaminophen results in decreased expression of CSF3 mRNA22230336
D020106AcrylamideAcrylamide results in increased expression of CSF3 mRNA27836571|2852632
D020106AcrylamideAcrylamide results in increased secretion of CSF3 protein27836571|2852632
D000242Cyclic AMPCyclic AMP results in increased expression of CSF3 protein7540958
D000447AldehydesAldehydes results in increased expression of CSF3 mRNA25014914
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CSF3 protein results in increased expression of BIRC3 mRNA]"12393423
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CSF3 protein results in increased expression of BIRC3 protein]"12393423
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [CSF3 protein results in increased phosphorylation of STAT3 protein]"12393423
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CSF3 mRNA16483693
C006632arsenic trioxideCSF3 protein inhibits the reaction [Tretinoin results in decreased uptake of arsenic trioxide]22940758
D001194AsbestosAsbestos results in increased expression of CSF3 mRNA22398240
D001194AsbestosAsbestos results in increased expression of CSF3 protein18795166
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased secretion of CSF3 protein"23017228
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of CSF3 mRNA"24160326|2575705
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased secretion of CSF3 protein"23937860
D017638Asbestos, Crocidolite"Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CSF3 protein]"23937860
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of CSF3 protein"26119930
D001379AzathioprineAzathioprine results in decreased expression of CSF3 mRNA19192274
D001554BenzeneCSF3 exon SNP affects the susceptibility to Benzene16230423
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased methylation of CSF3 promoter28329817
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CSF3 mRNA28351761
D004958EstradiolEstradiol affects the expression of CSF3 mRNA22574217
D004958EstradiolEstradiol results in increased expression of CSF3 mRNA16298037
D004958Estradiol[Progesterone co-treated with Estradiol] results in increased expression of CSF3 mRNA17404688
C006780bisphenol Abisphenol A results in increased expression of CSF3 mRNA25181051
D001761BleomycinBleomycin results in decreased expression of CSF3 mRNA15808516
C032688boric acidboric acid results in increased expression of CSF3 protein27206737
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of CSF3 mRNA18804290
C018475butyraldehydebutyraldehyde results in increased expression of CSF3 mRNA26079696
D002087ButyratesButyrates results in increased expression of CSF3 protein7540958
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CSF3 mRNA26790433
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CSF3 protein26790433
D019256Cadmium ChloridePolymyxin B promotes the reaction [Cadmium Chloride results in increased expression of CSF3 protein]26790433
D002251Carbon TetrachloridePPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CSF3 mRNA]18038451
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in increased expression of CSF3 mRNA21224055
D002713ChlorineChlorine results in increased expression of CSF3 protein23146759
D002713ChlorineChlorine results in increased expression of CSF3 mRNA18636392
D002713Chlorine[Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA18636392
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CSF3 mRNA18804290
D002794Choline[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Choline9018096
D003024ClozapineCSF3 protein inhibits the reaction [Clozapine results in increased expression of BAX mRNA]16160616
D003024ClozapineCSF3 protein inhibits the reaction [Clozapine results in increased expression of BIK mRNA]16160616
D003024ClozapineCSF3 protein inhibits the reaction [Clozapine results in increased expression of TP53 mRNA]16160616
D003401Creatine[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Creatine9018096
D003471CuprizoneCuprizone results in increased expression of CSF3 mRNA27523638
C009160cyclonitecyclonite results in increased expression of CSF3 mRNA25559034
D003840Deoxycholic AcidDeoxycholic Acid results in increased expression of CSF3 mRNA21224055
D003840Deoxycholic AcidEGR1 promotes the reaction [Deoxycholic Acid results in increased expression of CSF3 mRNA]21224055
C007262deoxynivalenoldeoxynivalenol results in increased expression of CSF3 mRNA27757495
D003907DexamethasoneDexamethasone results in increased expression of CSF3 mRNA16144937
D002945Cisplatin[Cisplatin co-treated with TNF protein] results in increased expression of CSF3 mRNA23103562
D002945CisplatinCisplatin results in increased expression of CSF3 mRNA26546572
D002945CisplatinCisplatin results in increased expression of CSF3 protein20844023
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CSF3 mRNA"14678569
D004128DimethylnitrosamineCSF3 protein affects the reaction [Dimethylnitrosamine affects the expression of IL18 mRNA]17869372
D004128DimethylnitrosamineCSF3 protein affects the reaction [Dimethylnitrosamine affects the expression of IL1A mRNA]17869372
D004128DimethylnitrosamineCSF3 protein affects the reaction [Dimethylnitrosamine results in increased expression of IFNB1 mRNA]17869372
D004128DimethylnitrosamineCSF3 protein affects the reaction [Dimethylnitrosamine results in increased expression of IL1R1 mRNA]17869372
D004128DimethylnitrosamineCSF3 protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]17869372
D004128DimethylnitrosamineCSF3 protein inhibits the reaction [Dimethylnitrosamine results in increased expression of TNF mRNA]17869372
D004128DimethylnitrosamineCSF3 protein promotes the reaction [Dimethylnitrosamine results in increased expression of IL1B mRNA]17869372
D004128DimethylnitrosamineCSF3 protein promotes the reaction [Dimethylnitrosamine results in increased expression of IL6 mRNA]17869372
D004137DinitrochlorobenzeneDinitrochlorobenzene results in increased expression of CSF3 mRNA18652873
D004237DiuronDiuron metabolite results in increased expression of CSF3 mRNA24172598
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in decreased expression of CSF3R protein]17334414
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in decreased expression of DES protein]17334414
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]17334414
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]17334414
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]17334414
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in increased expression of PTGS2 protein]17334414
D004317DoxorubicinCSF3 protein inhibits the reaction [Doxorubicin results in increased expression of FAS protein]16761189
D004317DoxorubicinCSF3 protein results in decreased susceptibility to Doxorubicin16761189
D004391DustDust results in increased expression of CSF3 mRNA17805423
D004726EndosulfanEndosulfan results in decreased expression of CSF3 protein26722802
C031818enterotoxin B, staphylococcal"enterotoxin B, staphylococcal results in increased expression of and results in increased secretion of CSF3 protein"25556216
C031818enterotoxin B, staphylococcal"enterotoxin B, staphylococcal results in increased expression of CSF3 protein"22646800
C031818enterotoxin B, staphylococcal"resveratrol inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of CSF3 protein]"22646800
D000069347Erlotinib HydrochlorideErlotinib Hydrochloride results in increased secretion of CSF3 protein27738319
C109799FK 706FK 706 inhibits the reaction [IL1B protein results in increased expression of CSF3 protein]12676771
C109799FK 706FK 706 inhibits the reaction [TNF protein results in increased expression of CSF3 protein]12676771
D005557FormaldehydeFormaldehyde results in decreased expression of CSF3 mRNA20655997
C070081fulvestrantfulvestrant results in decreased expression of CSF3 mRNA16298037
D005665FurosemideFurosemide results in increased expression of CSF3 mRNA16526316
C056507gemcitabinegemcitabine results in decreased expression of CSF3 protein20531411
C007834genipingenipin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]22687549
D005944GlucosamineGlucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]17109745
D005944GlucosamineGlucosamine results in increased expression of CSF3 mRNA17109745
D006046Gold[Gold co-treated with Silicon Dioxide] results in increased secretion of CSF3 protein22155353
D006046GoldGold results in increased secretion of CSF3 protein22155353
D006493HeparinHeparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA]16401727
C013015hesperetinhesperetin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
D017313FenretinideFenretinide results in increased expression of CSF3 mRNA28973697
D007294Inositol[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Inositol9018096
D053590Interleukin 1 Receptor Antagonist Protein"Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CSF3 protein]"23937860
D053590Interleukin 1 Receptor Antagonist ProteinInterleukin 1 Receptor Antagonist Protein results in decreased secretion of CSF3 protein27738319
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CSF3 mRNA25613284
C561695(+)-JQ1 compound(+)-JQ1 compound inhibits the reaction [[KRAS mutant form co-treated with TRP53 mutant form] results in increased expression of CSF3 protein]26390243
C433788lipopolysaccharide, E. coli O26-B6"lipopolysaccharide, E. coli O26-B6 results in increased expression of CSF3 mRNA"23090859
C433788lipopolysaccharide, E. coli O26-B6"nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CSF3 mRNA]"23090859
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of CSF3 protein"23306164
D008070Lipopolysaccharideshesperetin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA9122163
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CSF3 protein24707119
D008070Lipopolysaccharides[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CSF3 protein18437699
D008070LipopolysaccharidesPhloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
D008070LipopolysaccharidesSilymarin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
D008070Lipopolysaccharides"3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]"25843059
D008070Lipopolysaccharidesgenipin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]22687549
D008070LipopolysaccharidesIL6 protein affects the reaction [Lipopolysaccharides results in increased secretion of CSF3 protein]15804595
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein15135318
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of CSF3 mRNA12057914
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CSF3 mRNA20423518|2268754
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CSF3 protein19133137|2679043
D008070Lipopolysaccharidesmangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein]15135318
D008070Lipopolysaccharidesphenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]20423518
D008070LipopolysaccharidesPolymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]26790433
D008070Lipopolysaccharidesterameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]19133137
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CSF3 mRNA25613284
D008070LipopolysaccharidesHeparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA]16401727
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA16401727
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CSF3 mRNA18710323
D008070LipopolysaccharidesTriglycerides promotes the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]18710323
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CSF3 mRNA21641980
C013592mangiferinmangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein]15135318
C013592mangiferinmangiferin results in decreased expression of CSF3 mRNA15135318
D008627Mercuric ChlorideMercuric Chloride results in increased expression of CSF3 protein21984480
D008748MethylcholanthreneMethylcholanthrene affects the expression of CSF3 mRNA18804290
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"CSF3 protein inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of MTA1 protein]"27044752
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"CSF3 protein inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]"27044752
D008917MirexMirex results in increased expression of CSF3 mRNA23153324
D009151Mustard GasMustard Gas results in increased expression of CSF3 protein17894541
D009151Mustard GasMustard Gas results in increased expression of CSF3 mRNA25275893
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CSF3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CSF3 mRNA"25554681
C022838nickel chloride[nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CSF3 protein18437699
C022838nickel chloride"nickel chloride promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CSF3 mRNA]"23090859
C022838nickel chloridenickel chloride results in increased expression of CSF3 mRNA17312168
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CSF3 mRNA27935865
C000592118ONO-8430506ONO-8430506 results in decreased expression of CSF3 protein26071407
D010126Ozone[CPE affects the susceptibility to Ozone] which affects the expression of CSF3 protein23434795
D010126Ozone[LEP gene mutant form results in increased susceptibility to Ozone] which results in increased expression of CSF3 protein27472835
D010126OzoneOzone results in increased expression of CSF3 protein18315731
D010126Ozone[Ozone co-treated with Chlorine] results in increased expression of CSF3 mRNA18636392
D017239Paclitaxel[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Choline9018096
D017239Paclitaxel[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Creatine9018096
D017239Paclitaxel[CSF3 protein co-treated with Paclitaxel] results in decreased abundance of Inositol9018096
D010269ParaquatParaquat results in increased expression of CSF3 protein26988026
D052638Particulate MatterParticulate Matter affects the expression of CSF3 protein28189646
D052638Particulate MatterParticulate Matter analog results in decreased secretion of CSF3 protein20026096
D052638Particulate MatterParticulate Matter results in increased expression of CSF3 mRNA21708214
D052638Particulate MatterParticulate Matter results in increased expression of CSF3 protein22634322
D052638Particulate MatterParticulate Matter results in increased secretion of CSF3 protein23962744
C046012pentanalpentanal results in increased expression of CSF3 mRNA26079696
C058305phenethyl isothiocyanatephenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]20423518
D010693PhloretinPhloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
D011094PolyethyleneiminePolyethyleneimine results in increased secretion of CSF3 protein19444927
D011112Polymyxin BPolymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]26790433
D011112Polymyxin BPolymyxin B promotes the reaction [Cadmium Chloride results in increased expression of CSF3 protein]26790433
C467566pomalidomidepomalidomide results in increased secretion of CSF3 protein15292067
D011374Progesterone[Progesterone co-treated with Estradiol] results in increased expression of CSF3 mRNA17404688
D011374ProgesteroneProgesterone results in increased expression of CSF3 mRNA21549006
C005556propionaldehydepropionaldehyde results in increased expression of CSF3 mRNA26079696
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in decreased expression of CSF3 mRNA16298037
D011899RanitidineHeparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA]16401727
D011899Ranitidine[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA16401727
C059514resveratrolresveratrol inhibits the reaction [7-ketocholesterol results in increased expression of CSF3 protein]24895526
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
C059514resveratrolresveratrol analog results in decreased expression of CSF3 mRNA15652768
C059514resveratrol"resveratrol inhibits the reaction [enterotoxin B, staphylococcal results in increased expression of CSF3 protein]"22646800
C107087SCH 14988SCH 14988 results in increased expression of CSF3 mRNA9226180
C107087SCH 14988SCH 14988 results in increased expression of CSF3 mRNA9226180
C107087SCH 14988SCH 14988 results in increased expression of CSF3 protein9226180
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of CSF3 mRNA"24160326
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased secretion of CSF3 protein"23017228
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of CSF3 protein"17200189
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of CSF3 mRNA23806026|2589566
D012822Silicon DioxideSilicon Dioxide results in increased secretion of CSF3 protein22300531
D012822Silicon Dioxide[Gold co-treated with Silicon Dioxide] results in increased secretion of CSF3 protein22155353
D012822Silicon DioxideSilicon Dioxide results in increased secretion of CSF3 protein19073995
D012838SilymarinSilymarin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]24707119
C017947sodium arsenitesodium arsenite results in increased expression of CSF3 mRNA24516582
D012969Sodium FluorideSodium Fluoride results in decreased expression of CSF3 mRNA27862939
C538809sodium pentaboratesodium pentaborate analog results in increased expression of CSF3 protein27206737
C025399sodium tungstate(VI)sodium tungstate(VI) results in increased expression of CSF3 mRNA26164860
D053260SootSoot results in increased expression of CSF3 mRNA26551751
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CSF3 mRNA21641980
C061133tamibaroteneCSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]27737899
C061133tamibaroteneCSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]27737899
C061133tamibaroteneCSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]27737899
C061133tamibaroteneCSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]27737899
C061133tamibaroteneCSF3 protein promotes the reaction [tamibarotene results in increased expression of RARB mRNA]27737899
C061133tamibarotene[tamibarotene co-treated with CSF3 protein] results in increased expression of CEACAM8 mRNA27737899
C061133tamibarotenetamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]27737899
C061133tamibarotenetamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]27737899
C061133tamibarotenetamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]27737899
C061133tamibarotenetamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]27737899
C061133tamibarotenetamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]27737899
C061133tamibarotenetamibarotene promotes the reaction [CSF3 protein results in increased expression of RARB mRNA]27737899
D013629TamoxifenTamoxifen results in decreased expression of CSF3 mRNA16298037
D013656Taurocholic AcidTaurocholic Acid results in increased expression of CSF3 mRNA21224055
C076852terameprocolterameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]19133137
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CSF3 mRNA28351761
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CSF3 mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [tributyltin results in increased expression of CSF3 mRNA]22749964
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CSF3 mRNA12167310|1467856
D013755Tetradecanoylphorbol Acetate[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA9122163
D013755Tetradecanoylphorbol Acetate[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF3 mRNA16979875
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CSF3 mRNA25613284
D013792ThalidomideThalidomide results in decreased activity of CSF3 protein17557286
D013806TheophyllineTheophylline results in increased expression of CSF3 protein7540958
C009495titanium dioxidetitanium dioxide affects the expression of CSF3 mRNA19695317
C009495titanium dioxidetitanium dioxide results in increased expression of CSF3 mRNA21259345
C009495titanium dioxidetitanium dioxide results in increased expression of CSF3 protein23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CSF3 mRNA17494027|2163613
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CSF3 protein21636132
C024746tobacco tartobacco tar results in increased expression of CSF3 mRNA19559774
D014118Toxins, Biological"Toxins, Biological affects the expression of CSF3 mRNA"19682533
D014212TretinoinCSF3 protein inhibits the reaction [Tretinoin results in decreased uptake of arsenic trioxide]22940758
D014212TretinoinCSF3 protein promotes the reaction [Tretinoin results in increased expression of CD33 protein]12627849
D014212TretinoinCSF3 protein promotes the reaction [Tretinoin results in increased expression of ITGAL protein]18055984
D014212TretinoinCSF3 protein promotes the reaction [Tretinoin results in increased expression of ITGAM protein]18055984
D014212TretinoinCSF3 protein promotes the reaction [Tretinoin results in increased expression of ITGB2 protein]18055984
D014212TretinoinCSF3 protein promotes the reaction [Tretinoin results in increased expression of MME protein]12627849
D014212TretinoinTretinoin results in decreased expression of CSF3 protein17118196
C011559tributyltinTetrachlorodibenzodioxin promotes the reaction [tributyltin results in increased expression of CSF3 mRNA]22749964
C011559tributyltintributyltin results in increased expression of CSF3 mRNA22749964
D014280TriglyceridesTriglycerides promotes the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]18710323
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of CSF3 protein23596210
C057693troglitazonetroglitazone results in decreased expression of CSF3 mRNA28934090
D014635Valproic AcidValproic Acid affects the expression of CSF3 mRNA17292431
D001335Vehicle EmissionsVehicle Emissions affects the expression of CSF3 protein28189646
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of CSF3 gene25560391
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CSF3 mRNA27935865
D015032Zinc[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF3 mRNA16979875
D019287Zinc SulfateZinc Sulfate results in decreased expression of CSF3 mRNA27504894

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005125cytokine activity-IBA21873635  
GO:0005125cytokine activity-IDA23001182  
GO:0005125cytokine activity-NAS15664994  
GO:0005130granulocyte colony-stimulating factor receptor binding-IBA21873635  
GO:0008083growth factor activity-IBA21873635  
GO:0019899enzyme binding-IPI12393522  
GO ID GO Term Qualifier Evidence PubMed
GO:0006955immune response-IEA-  
GO:0007275multicellular organism development-TAS2420009  
GO:0008284positive regulation of cell proliferation-IBA21873635  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0014068positive regulation of phosphatidylinositol 3-kinase signaling-IDA23001182  
GO:0019221cytokine-mediated signaling pathway-NAS15664994  
GO:0019221cytokine-mediated signaling pathway-TAS-  
GO:0030838positive regulation of actin filament polymerization-IDA23001182  
GO:0030851granulocyte differentiation-NAS15664994  
GO:0032092positive regulation of protein binding-IDA23001182  
GO:0033138positive regulation of peptidyl-serine phosphorylation-IDA23001182  
GO:0045471response to ethanol-IEA-  
GO:0045639positive regulation of myeloid cell differentiation-IBA21873635  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA23001182  
GO:0050731positive regulation of peptidyl-tyrosine phosphorylation-IDA23001182  
GO:0051091positive regulation of DNA-binding transcription factor activity-IDA23001182  
GO:0051897positive regulation of protein kinase B signaling-IDA23001182  
GO:0071222cellular response to lipopolysaccharide-IEA-  
GO:0071345cellular response to cytokine stimulus-IDA23001182  
GO:1901215negative regulation of neuron death-IEA-  
GO:2000251positive regulation of actin cytoskeleton reorganization-IDA23001182  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IBA21873635  
KEGG ID KEGG Term
hsa04060Cytokine-cytokine receptor interaction
hsa04630Jak-STAT signaling pathway
hsa04640Hematopoietic cell lineage
hsa05144Malaria
Reactome ID Reactome Term Evidence
R-HSA-1280215Cytokine Signaling in Immune systemTAS
R-HSA-168256Immune SystemTAS
R-HSA-449147Signaling by InterleukinsTAS
R-HSA-449836Other interleukin signalingTAS
R-HSA-6783783Interleukin-10 signalingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18353856Association of genetic variations in the CSF2 and CSF3 genes with lung function in smoking-induced COPD. (2008 Jul)He JQEur Respir J