Gene: GLT1D1

144423
-
glycosyltransferase 1 domain containing 1
protein-coding
12q24.33
Ensembl:ENSG00000151948 Vega:OTTHUMG00000168437 UniprotKB:Q96MS3
NC_000012.12
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.759e-1 (AD)  2.682e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DLG30.976
NMNAT20.974
ATP8A20.972
SVOP0.97
MAP7D20.968
ADD20.966
NSF0.965
GDA0.964
CHGB0.963
DYNC1I10.963

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
REST-0.602
YES1-0.601
HEY2-0.601
RAI14-0.574
RAB13-0.572
TGIF1-0.57
MYL3-0.57
RNF135-0.568
WWTR1-0.567
CNN2-0.566

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of GLT1D1 mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of GLT1D1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of GLT1D1 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of GLT1D1 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of GLT1D1 mRNA"25510870
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GLT1D1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GLT1D1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GLT1D1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GLT1D1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of GLT1D1 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of GLT1D1 mRNA17562736
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of GLT1D1 mRNA"23195993
D001280AtrazineAtrazine results in increased expression of GLT1D1 mRNA22378314
C547126AZM551248AZM551248 results in increased expression of GLT1D1 mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of GLT1D1 mRNA20064835
C006780bisphenol Abisphenol A results in decreased expression of GLT1D1 mRNA25181051
D004397FonofosFonofos results in increased methylation of GLT1D1 promoter22847954
C016517indole-3-carbinolindole-3-carbinol affects the expression of GLT1D1 mRNA21396975
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of GLT1D1 mRNA28001369
D009532NickelNickel results in decreased expression of GLT1D1 mRNA23195993
D010278ParathionParathion results in increased methylation of GLT1D1 promoter22847954
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of GLT1D1 mRNA"25510870
D010634PhenobarbitalPhenobarbital results in increased expression of GLT1D1 mRNA19084549
D010936Plant ExtractsPlant Extracts results in increased expression of GLT1D1 mRNA23557933
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of GLT1D1 mRNA28903501
D011374ProgesteroneProgesterone results in increased expression of GLT1D1 mRNA21540246
C012568terbufosterbufos results in increased methylation of GLT1D1 promoter22847954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of GLT1D1 mRNA22298810
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of GLT1D1 mRNA28973375
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased methylation of GLT1D1 gene26756918
D014212TretinoinTretinoin results in decreased expression of GLT1D1 mRNA23724009
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GLT1D1 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of GLT1D1 mRNA24935251|2627250
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GLT1D1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of GLT1D1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of GLT1D1 mRNA26272509
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of GLT1D1 gene25560391
C111237vorinostatvorinostat results in decreased expression of GLT1D1 mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
GO:0005829cytosol-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27564456DNA methylation profiling in human lung tissue identifies genes associated with COPD. (2016 Aug 26)Morrow JDEpigenetics