Gene: MIPOL1

145282
CCDC193
mirror-image polydactyly 1
protein-coding
14q13.3-q21.1
Ensembl:ENSG00000151338 MIM:606850 Vega:OTTHUMG00000140252 UniprotKB:Q8TD10
NG_027724.1
SNP Mapped
2   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.574e-1 (AD)  3.118e-3 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11621659chr14:37578238 (GRCh38.p7)G>Anicotine dependenceSNV(Single Nucleotide Variation)
rs981794chr14:37571550 (GRCh38.p7)A>Gnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SCAF110.767
POLK0.76
ZNF8000.742
PHC30.731
CDC730.728
MANEA0.727
FNDC3A0.726
AQR0.726
SLAIN20.723
LYSMD30.722

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.301
OR4F29-0.289
ALG1L-0.268
HES5-0.251
C12orf54-0.247
TNNT1-0.217
ARSF-0.216
ENHO-0.214
NANOS3-0.21
HES6-0.207

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D020106AcrylamideAcrylamide results in increased expression of MIPOL1 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of MIPOL1 mRNA19770486
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of MIPOL1 mRNA21298039
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of MIPOL1 mRNA20106945|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of MIPOL1 mRNA19770486|2171566
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of MIPOL1 mRNA17484886
D003010ClorgylineClorgyline results in increased expression of MIPOL1 mRNA19691856
C018021cobaltous chloridecobaltous chloride results in decreased expression of MIPOL1 mRNA19320972
D016572CyclosporineCyclosporine results in increased expression of MIPOL1 mRNA25562108
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MIPOL1 mRNA17361019|2126653
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of MIPOL1 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of MIPOL1 mRNA27392435
C000944dicrotophosdicrotophos results in decreased expression of MIPOL1 mRNA28302478
D004041Dietary FatsDietary Fats results in increased expression of MIPOL1 mRNA25016146
D004726EndosulfanEndosulfan results in decreased expression of MIPOL1 protein26722802
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MIPOL1 mRNA22079256
D006918HydroxyureaHydroxyurea results in increased mutagenesis of MIPOL1 gene16868089
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of MIPOL1 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of MIPOL1 mRNA27392435
C045463leflunomideleflunomide results in increased expression of MIPOL1 mRNA28988120
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of MIPOL1 mRNA"24972896
D008727MethotrexateMethotrexate results in increased expression of MIPOL1 mRNA24449571
D008770MethylnitrosoureaMethylnitrosourea results in increased mutagenesis of MIPOL1 gene16868089
C568376MT19c compoundMT19c compound results in increased expression of MIPOL1 mRNA21781307
C058305phenethyl isothiocyanateMIPOL1 protein binds to phenethyl isothiocyanate21838287
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MIPOL1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of MIPOL1 mRNA22079256
D011192Potassium DichromatePotassium Dichromate results in decreased expression of MIPOL1 mRNA23608068
D011794QuercetinQuercetin results in decreased expression of MIPOL1 mRNA21632981
C012589trichostatin Atrichostatin A results in increased expression of MIPOL1 mRNA24935251
D014520UrethaneUrethane results in increased expression of MIPOL1 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of MIPOL1 mRNA25979313
D014638VanadatesVanadates results in decreased expression of MIPOL1 mRNA22714537

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  25910212  26871637  
GO:0042802identical protein binding-IPI25416956  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA19667180  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal