Gene: ZNF570

148268
-
zinc finger protein 570
protein-coding
19q13.12
Ensembl:ENSG00000171827 Vega:OTTHUMG00000048176 UniprotKB:Q96NI8
NC_000019.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.896e-1 (AD)  7.739e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HCFC20.828
RBM410.818
SLMAP0.817
USP340.813
DNAJC240.797
ZNF3220.795
PCMTD10.79
ERCC6L20.79
USP370.789
PIAS10.789

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PLA2G5-0.351
OR4F5-0.335
OR4F29-0.329
TMEM86B-0.313
CRYBB2-0.306
S100A1-0.301
SLC7A10-0.3
VCX3A-0.295
FAM229A-0.294
ZNF296-0.287

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF570 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF570 mRNA"27188386
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of ZNF570 mRNA21298039
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of ZNF570 mRNA24449571
D016572CyclosporineCyclosporine results in increased expression of ZNF570 mRNA25562108
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of ZNF570 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of ZNF570 mRNA27392435
D004397FonofosFonofos results in increased methylation of ZNF570 promoter22847954
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of ZNF570 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of ZNF570 mRNA27392435
D010278ParathionParathion results in increased methylation of ZNF570 promoter22847954
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ZNF570 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of ZNF570 mRNA26272509
C012568terbufosterbufos results in increased methylation of ZNF570 promoter22847954
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ZNF570 mRNA"26179874
D014520UrethaneUrethane results in increased expression of ZNF570 mRNA28818685

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28852427Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma. (2017)Shen SClin Epigenetics