Gene: C1orf127

148345
-
chromosome 1 open reading frame 127
protein-coding
1p36.22
Ensembl:ENSG00000175262 Vega:OTTHUMG00000002032 UniprotKB:Q8N9H9
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.835e-1 (AD)  2.253e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11121671chr1:10983723 (GRCh38.p7)C>A / C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GPR1490.547
STRIP20.544
C1QTNF20.542
ATG9B0.536
PRRT40.525
TNK10.523
NR1I30.52
RAB40A0.511
CD8A0.505
NETO20.504

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FXYD3-0.316
ROM1-0.316
MYL3-0.296
MYOT-0.291
TGFB3-0.286
NUPR1-0.281
OLAH-0.276
SCGB1D2-0.276
HIST1H2AC-0.271
RAB13-0.269

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C018475butyraldehydebutyraldehyde results in increased expression of C1ORF127 mRNA26079696
C005556propionaldehydepropionaldehyde results in decreased expression of C1ORF127 mRNA26079696

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0007507heart development-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal