Gene: PHF13

148479
PHF5|SPOC1
PHD finger protein 13
protein-coding
1p36.31
Ensembl:ENSG00000116273 Vega:OTTHUMG00000001439 UniprotKB:Q86YI8
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.738e-1 (AD)  1.793e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10779795chr1:6617004 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PSMD110.893
TMEM2480.892
NRBP10.888
SART30.887
KDM1A0.883
VCP0.883
LRRC410.882
PSMD30.881
CSNK1D0.877
STX50.875

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.64
OR4F29-0.577
MTRNR2L9-0.326
MTRNR2L6-0.323
P2RY14-0.318
MTRNR2L10-0.309
MTRNR2L2-0.274
TTLL10-0.27
CTNNA3-0.268
FMO3-0.255

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF13 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF13 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of PHF13 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of PHF13 mRNA17562736
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of PHF13 mRNA24449571
D001280AtrazineAtrazine results in increased expression of PHF13 mRNA22378314
D001554BenzeneBenzene results in increased expression of PHF13 mRNA19162166
D001564Benzo(a)pyreneAHR protein affects the reaction [Benzo(a)pyrene affects the expression of PHF13 mRNA]22228805
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of PHF13 mRNA22228805
C044887beta-methylcholinebeta-methylcholine affects the expression of PHF13 mRNA21179406
C006780bisphenol Abisphenol A results in increased methylation of PHF13 promoter27312807
C006780bisphenol Abisphenol A results in increased expression of PHF13 mRNA25181051
D019327Copper SulfateCopper Sulfate results in increased expression of PHF13 mRNA19549813
D016572CyclosporineCyclosporine results in increased expression of PHF13 mRNA20106945
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of PHF13 mRNA21266533
D002945CisplatinCisplatin results in increased expression of PHF13 mRNA27594783
C024629dimethyl phthalatedimethyl phthalate affects the expression of PHF13 mRNA26924002
D005557FormaldehydeFormaldehyde results in decreased expression of PHF13 mRNA20655997
D005557FormaldehydeFormaldehyde results in increased expression of PHF13 mRNA23649840
D007649KetamineKetamine results in decreased expression of PHF13 mRNA20080153
D008694MethamphetamineMethamphetamine results in increased expression of PHF13 mRNA19564919
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of PHF13 mRNA23649840
D010634PhenobarbitalPhenobarbital affects the expression of PHF13 mRNA19159669
C006253pirinixic acidpirinixic acid results in increased expression of PHF13 mRNA23811191
D011374ProgesteroneProgesterone results in decreased expression of PHF13 mRNA19690047
D011441PropylthiouracilPropylthiouracil results in increased expression of PHF13 mRNA24780913
D012999SomanSoman results in increased expression of PHF13 mRNA19281266
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PHF13 mRNA21570461
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PHF13 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of PHF13 mRNA26272509
D014635Valproic AcidValproic Acid results in increased expression of PHF13 mRNA15799026
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of PHF13 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003682chromatin binding-IBA21873635  
GO:0003682chromatin binding-IDA19638409  
GO:0035064methylated histone binding-NAS19638409  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000278mitotic cell cycle-IMP19638409  
GO:0006325chromatin organization-IEA-  
GO:0007059chromosome segregation-IMP19638409  
GO:0007076mitotic chromosome condensation-IBA21873635  
GO:0007076mitotic chromosome condensation-IMP19638409  
GO:0051301cell division-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IBA21873635  
GO:0005634nucleus-IDA19638409  
GO:0005654nucleoplasm-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal