Gene: SLC35F3

148641
-
solute carrier family 35 member F3
protein-coding
1q42.2
Ensembl:ENSG00000183780 Vega:OTTHUMG00000037929 UniprotKB:Q8IY50
NC_000001.11
SNP Mapped
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.268e-1 (AD)  8.011e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2045518chr1:234094642 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TMEM2460.936
NELL20.935
SH3GL20.935
PRRG30.935
GLS0.934
PCSK20.933
CNKSR20.931
RYR20.931
NSF0.93
GLS20.929

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ASB4-0.577
COPZ2-0.543
YES1-0.541
FZD10-0.535
HEY2-0.533
MBNL3-0.529
MYL3-0.528
RNF135-0.525
PARD3B-0.511
TFPI2-0.51

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC35F3 mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC35F3 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC35F3 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC35F3 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC35F3 mRNA"25510870
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC35F3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC35F3 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of SLC35F3 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of SLC35F3 mRNA17562736
C015001arsenitearsenite results in increased methylation of SLC35F3 promoter23974009
C487081belinostatbelinostat results in decreased expression of SLC35F3 mRNA27188386
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of SLC35F3 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of SLC35F3 mRNA27392435
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of SLC35F3 mRNA23649840
D005557FormaldehydeFormaldehyde results in decreased expression of SLC35F3 mRNA23649840
C412815GW 4064GW 4064 results in decreased expression of SLC35F3 mRNA26655953
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of SLC35F3 mRNA27392435
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of SLC35F3 mRNA23649840
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SLC35F3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SLC35F3 mRNA"25554681
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SLC35F3 mRNA"25510870
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC35F3 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of SLC35F3 mRNA26272509
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SLC35F3 mRNA19710929
D010936Plant ExtractsPlant Extracts results in decreased expression of SLC35F3 mRNA23557933
D010938Plant OilsPlant Oils results in decreased expression of SLC35F3 mRNA23370395
C005556propionaldehydepropionaldehyde results in increased expression of SLC35F3 mRNA26079696
C017947sodium arsenitesodium arsenite results in decreased expression of SLC35F3 mRNA22714537
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SLC35F3 mRNA21570461
D014212TretinoinTretinoin results in decreased expression of SLC35F3 mRNA23724009
D014635Valproic AcidValproic Acid results in decreased expression of SLC35F3 mRNA23179753
D014635Valproic AcidValproic Acid results in increased expression of SLC35F3 mRNA28001369
D014635Valproic AcidValproic Acid results in increased methylation of SLC35F3 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0015888thiamine transport-IBA21873635  
GO:0015888thiamine transport-IDA24509276  
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal