Gene: MFSD4A

148808
MFSD4|UNQ3064
major facilitator superfamily domain containing 4A
protein-coding
1q32.1
Ensembl:ENSG00000174514 Vega:OTTHUMG00000037197 UniprotKB:Q8N468
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.503e-1 (AD)  7.673e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs7515820chr1:205584967 (GRCh38.p7)A>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MFSD4A mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MFSD4A mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MFSD4A mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MFSD4A mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MFSD4A mRNA"25510870
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of MFSD4A mRNA28522335
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of MFSD4A mRNA20064835
C006780bisphenol Abisphenol A affects the expression of MFSD4A mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of MFSD4A mRNA25181051
D002737ChloropreneChloroprene results in decreased expression of MFSD4A mRNA23125180
D003300CopperCopper deficiency results in increased expression of MFSD4A mRNA26033743
D013759DronabinolDronabinol results in increased expression of MFSD4A mRNA16616335
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of MFSD4A mRNA21266533
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of MFSD4A mRNA27392435
D002945CisplatinCisplatin results in increased expression of MFSD4A mRNA27392435
D004041Dietary FatsDietary Fats results in decreased expression of MFSD4A mRNA18042831|1845759
D019422Dietary SucroseDietary Sucrose results in increased expression of MFSD4A mRNA26033743
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of MFSD4A mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of MFSD4A mRNA23649840
C039281furanfuran results in increased methylation of MFSD4A gene22079235
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of MFSD4A mRNA27392435
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with resveratrol] results in increased expression of MFSD4A mRNA26667767
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of MFSD4A mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of MFSD4A mRNA"26251327
C028473N-acetyl-4-benzoquinoneimineMFSD4A gene SNP affects the susceptibility to N-acetyl-4-benzoquinoneimine21177773
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of MFSD4A mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of MFSD4A mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of MFSD4A mRNA"25620056
D009532NickelNickel results in decreased expression of MFSD4A mRNA24768652|2558310
D000073878Palm OilPalm Oil results in decreased expression of MFSD4A mRNA18042831
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MFSD4A mRNA"25510870
D010416PentachlorophenolPentachlorophenol results in increased expression of MFSD4A mRNA24642059
C006253pirinixic acidpirinixic acid results in decreased expression of MFSD4A mRNA17426115
C005556propionaldehydepropionaldehyde results in increased expression of MFSD4A mRNA26079696
D011441PropylthiouracilPropylthiouracil results in decreased expression of MFSD4A mRNA24780913
C059514resveratrol[Lipopolysaccharides co-treated with resveratrol] results in increased expression of MFSD4A mRNA26667767
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of MFSD4A mRNA25895662
D012969Sodium FluorideSodium Fluoride results in decreased expression of MFSD4A mRNA27862939
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of MFSD4A mRNA19465110
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of MFSD4A mRNA"26743178
D014501UraniumUranium affects the expression of MFSD4A mRNA15672453
C005460uranyl acetateuranyl acetate affects the expression of MFSD4A mRNA15672453
D014635Valproic AcidValproic Acid results in increased expression of MFSD4A mRNA28001369
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of MFSD4A gene25560391
C025643vinclozolinvinclozolin results in decreased expression of MFSD4A mRNA23034163
D015032ZincZinc deficiency results in increased expression of MFSD4A mRNA20857495
C088658zoledronic acidzoledronic acid results in decreased expression of MFSD4A mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005355glucose transmembrane transporter activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:1904659glucose transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal