Gene: CTGF

1490
CCN2|HCS24|IGFBP8|NOV2
connective tissue growth factor
protein-coding
6q23.2
Ensembl:ENSG00000118523 MIM:121009 Vega:OTTHUMG00000015573 UniprotKB:P29279
NG_016131.1
PubMed
CD|ND
17   
2.421e-1 (AD)  9.017e-1 (ND)   (Frontal_Cortex)
4.068e-1 (AD)  7.596e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KDR0.647
EDN10.645
PALMD0.643
LAYN0.641
BMP60.64
PAPSS20.625
PTPRB0.623
ROBO40.623
MCAM0.619
MYCT10.618

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KCNG1-0.386
TMEM221-0.378
NOG-0.368
CNGB1-0.354
CHRNA2-0.347
CUX2-0.345
POU3F1-0.345
CRH-0.342
DLX1-0.341
CALB2-0.339

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4327471,1-dimethylbutyl-1-deoxy-Delta(9)-THC"1,1-dimethylbutyl-1-deoxy-Delta(9)-THC results in decreased expression of CTGF mRNA"15313899
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of CTGF mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Diethylnitrosamine] results in increased expression of CTGF mRNA"21391223
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of and results in increased secretion of CTGF protein]"19429239
C09724015-deoxy-delta(12,14)-prostaglandin J2"15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]"19429239
C09724015-deoxy-delta(12,14)-prostaglandin J2"SMAD2 protein modified form affects the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [TGFB1 protein results in increased expression of CTGF]]"19429239
C0326681-nitropyrene1-nitropyrene results in increased expression of CTGF mRNA19041380
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of CTGF mRNA19933214
C1016702-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate"2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [kallidin, des-Arg(10)- results in increased expression of CTGF mRNA]"15703175
C1016702-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]15703175
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one analog inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]26054450
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of CTGF mRNA17965732
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of CTGF protein17965732
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the expression of CTGF mRNA"19414516
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CTGF mRNA]"19414516
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of CTGF mRNA]"19414516
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in decreased expression of CTGF mRNA"21724226
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran affects the expression of CTGF mRNA"20702594
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in decreased expression of CTGF mRNA"21724226
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of CTGF mRNA"25710175
C0645152',4'-dichlorobenzamil amiloride"2',4'-dichlorobenzamil amiloride inhibits the reaction [kallidin, des-Arg(10)- results in increased expression of CTGF mRNA]"15703175
C0645152',4'-dichlorobenzamil amiloride"2',4'-dichlorobenzamil amiloride inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]"15703175
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one analog inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]26054450
C5116212-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTGF mRNA]23196670
C560356(2S,4R)-methyl-1-acetyl-4-(N-(4-bromophenyl)sulfamoyloxy)pyrrolidine-2-carboxylate"(2S,4R)-methyl-1-acetyl-4-(N-(4-bromophenyl)sulfamoyloxy)pyrrolidine-2-carboxylate results in decreased expression of CTGF protein"21349324
C0188552-tert-butylhydroquinone2-tert-butylhydroquinone results in decreased expression of CTGF mRNA16014739
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl affects the expression of CTGF mRNA"20702594
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CTGF mRNA"23196670
C0144643,4-dichloroaniline"3,4-dichloroaniline results in decreased expression of CTGF mRNA"24172598
C0179063-dinitrobenzene3-dinitrobenzene results in increased expression of CTGF mRNA24140754
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of CTGF mRNA"25380136
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of CTGF mRNA"25912373
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
D000079AcetaldehydeAcetaldehyde results in increased expression of CTGF mRNA19280452
D000079AcetaldehydeCTGF protein results in increased abundance of Acetaldehyde19280452
D000079Acetaldehyde[Ethanol results in increased expression of CTGF protein] which results in increased abundance of Acetaldehyde19280452
D000082AcetaminophenAcetaminophen affects the expression of CTGF mRNA25458485
D000082AcetaminophenAcetaminophen results in decreased expression of CTGF mRNA22230336
D000082AcetaminophenAcetaminophen results in increased expression of CTGF mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of CTGF mRNA15606129|1756273
D000082AcetaminophenAcetaminophen results in increased expression of CTGF mRNA11264010|1239296
D000082AcetaminophenNOS2 protein inhibits the reaction [Acetaminophen results in increased expression of CTGF mRNA]12392966
D000082AcetaminophenTNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of CTGF mRNA]14550746
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Streptozocin results in increased expression of CTGF protein]17270171
C109238acylineacyline results in decreased expression of CTGF mRNA17510436
D000242Cyclic AMP"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of CTGF mRNA]"19414516
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of CTGF gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CTGF mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CTGF mRNA19770486
D000450AldosteroneAldosterone results in increased expression of CTGF protein17278980
D000450AldosteroneSpironolactone inhibits the reaction [Aldosterone results in increased expression of CTGF protein]17278980
C038491allyl sulfideallyl sulfide inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
C038491allyl sulfideallyl sulfide inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D000509alpha-Fetoproteinsalpha-Fetoproteins inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CTGF mRNA]15994428
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CTGF mRNA16483693
C030419andrographolide[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CTGF mRNA19737545
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of CTGF mRNA24449571
C000228aristolochic acid Iaristolochic acid I inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of CTGF protein]24412304
D034341Aristolochic AcidsAristolochic Acids results in increased expression of CTGF mRNA19717638
D001151ArsenicArsenic affects the expression of CTGF protein24675094
D001151ArsenicArsenic results in increased expression of CTGF mRNA23942117
D001151ArsenicArsenic results in increased expression of CTGF mRNA24348802
D001151ArsenicGrape Seed Extract inhibits the reaction [Arsenic results in increased expression of CTGF mRNA]24348802
C006632arsenic trioxidearsenic trioxide inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]24762191
D001194AsbestosAsbestos results in decreased expression of CTGF mRNA22076105
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of CTGF mRNA"18687144
C011669ascorbate-2-phosphateascorbate-2-phosphate results in decreased expression of CTGF mRNA17306970
D001241AspirinAspirin inhibits the reaction [Glucose results in increased expression of CTGF mRNA]14586741
D001241AspirinAspirin inhibits the reaction [Streptozocin results in increased expression of CTGF mRNA]14586741
D001280AtrazineAtrazine results in increased expression of CTGF mRNA25616260
D001280AtrazineAtrazine results in increased expression of CTGF protein25616260
D001280AtrazineESR1 protein promotes the reaction [Atrazine results in increased expression of CTGF protein]25616260
D001280AtrazineGPER1 protein promotes the reaction [Atrazine results in increased expression of CTGF protein]25616260
C447119bazedoxifenebazedoxifene results in increased expression of CTGF mRNA19914376
C487081belinostatbelinostat results in increased expression of CTGF mRNA19606018|2367160
C044946benazeprilbenazepril results in decreased expression of CTGF mRNA17121042
D001548Benzalkonium CompoundsBenzalkonium Compounds results in decreased expression of CTGF mRNA25377654
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased expression of CTGF mRNA19737606
D019324beta-Naphthoflavone[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CTGF mRNA19737545
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CTGF mRNA15240111
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CTGF mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CTGF mRNA20106945|2163298
D001564Benzo(a)pyreneAHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of CTGF mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CTGF mRNA15034205|1977048
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CTGF mRNA21569818|2222880
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CTGF mRNA"20018196
D004958EstradiolESR1 protein promotes the reaction [Estradiol results in increased expression of CTGF protein]25616260
D004958EstradiolEstradiol affects the expression of CTGF mRNA14699072|2532141
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CTGF mRNA20823114
D004958EstradiolEstradiol results in increased expression of CTGF mRNA19153601|2561626
D004958EstradiolEstradiol results in increased expression of CTGF protein25616260
D004958EstradiolGPER1 protein promotes the reaction [Estradiol results in increased expression of CTGF protein]25616260
D004958EstradiolEstradiol results in increased expression of CTGF mRNA19484750
C020228betaninbetanin inhibits the reaction [Fructose results in increased expression of CTGF protein]25559852
D001629BezafibrateBezafibrate inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]19429239
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in increased expression of CTGF mRNA25912373
C070515bisindolylmaleimide Ibisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CTGF mRNA]10026205
C006780bisphenol Abisphenol A affects the expression of CTGF mRNA20170705
C006780bisphenol Abisphenol A promotes the reaction [CTGF protein binds to ESR1 protein]27156127
C006780bisphenol Abisphenol A results in decreased expression of CTGF mRNA27685785|2927551
C006780bisphenol Abisphenol A results in increased expression of CTGF mRNA22552965
C006780bisphenol Abisphenol A results in increased expression of CTGF protein22552965
C006780bisphenol AGPER1 mRNA affects the reaction [bisphenol A results in increased expression of CTGF protein]22552965
C006780bisphenol Abisphenol A results in increased expression of CTGF mRNA24586524
C006780bisphenol Abisphenol A affects the expression of CTGF mRNA25181051
C006780bisphenol Abisphenol A results in decreased expression of CTGF protein24552547
D001761BleomycinBleomycin results in increased expression of CTGF mRNA19080365|2681784
D001761BleomycinBleomycin results in increased expression of CTGF protein19080365
D001761Bleomycin[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D001761Bleomycin[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D001761Bleomycin[MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D001761BleomycinSimvastatin inhibits the reaction [Bleomycin results in increased expression of CTGF mRNA]19080365
D001761BleomycinSimvastatin inhibits the reaction [Bleomycin results in increased expression of CTGF protein]19080365
D020122tert-Butylhydroperoxide[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CTGF mRNA20847119
D020122tert-Butylhydroperoxidepioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CTGF mRNA]20847119
D020122tert-Butylhydroperoxide[rosiglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CTGF mRNA20847119
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide affects the expression of CTGF mRNA23410634
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in decreased expression of CTGF mRNA20847119
D020122tert-Butylhydroperoxide[troglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CTGF mRNA20847119
D020122tert-Butylhydroperoxidetroglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CTGF mRNA]20847119
C584509C646 compoundC646 compound results in decreased expression of CTGF mRNA26191083
D002104CadmiumCadmium inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
D002104CadmiumCadmium results in increased expression of CTGF mRNA15240111
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CTGF mRNA26314618
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CTGF mRNA26472689
D019256Cadmium ChlorideMT3 affects the reaction [Cadmium Chloride affects the expression of CTGF mRNA]20371981
D019256Cadmium ChlorideCadmium Chloride affects the expression of CTGF mRNA22110744
C081643candesartancandesartan results in decreased expression of CTGF mRNA16685210
C077793candesartan cilexetilcandesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of CTGF protein]27889505
D002220CarbamazepineCarbamazepine affects the expression of CTGF mRNA25979313
D002251Carbon TetrachlorideADIPOQ protein affects the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]14724832
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CTGF mRNA14724832|2704221
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CTGF protein17565644|1765781
D002251Carbon TetrachlorideHAS3 protein affects the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]27042213
D002251Carbon Tetrachloriderofecoxib inhibits the reaction [Carbon Tetrachloride results in increased expression of CTGF protein]17565644
D002251Carbon TetrachlorideSMAD7 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of CTGF protein]17657819
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CTGF mRNA16484506|1665239
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CTGF protein16420518|1665239
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased activity of TGFB1 protein]16652398
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]16652398
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]16652398
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased expression of CTGF protein]16652398
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]16652398
D002251Carbon TetrachlorideCTGF affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]16652398
D002251Carbon Tetrachloridepioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]16484506
D002251Carbon TetrachlorideQuercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]22989100
C010063carbonyl sulfidecarbonyl sulfide results in increased expression of CTGF mRNA19395590
D002331CarnitineCarnitine inhibits the reaction [sunitinib results in increased expression of CTGF mRNA]26581635
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CTGF mRNA24763279
D002509CephaloridineCephaloridine results in decreased expression of CTGF mRNA18500788
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of CTGF mRNA26272509
C100187chloropicrinchloropicrin results in increased expression of CTGF mRNA26352163
D002737ChloropreneChloroprene results in increased expression of CTGF mRNA23125180
D004390ChlorpyrifosChlorpyrifos results in increased expression of CTGF mRNA21356183
D004390ChlorpyrifosChlorpyrifos affects the expression of CTGF mRNA21496282
D002793Cholic Acids[Cyclosporine co-treated with Cholic Acids] affects the expression of CTGF mRNA27344345
D002794CholineCCL2 protein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA]20697377
D002794Choline[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA18991162
D002794Choline[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein18991162
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CTGF20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTGF gene20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTGF mRNA20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA20697377|2291529
D002794CholineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA]22915297
D002794Cholinerosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA]18991162
D002794Cholinerosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein]18991162
C012843cinnamic aldehydecinnamic aldehyde results in decreased expression of CTGF mRNA17178418
D003035CobaltCobalt results in decreased expression of CTGF mRNA17967803
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of CTGF mRNA]17034590
C018021cobaltous chloridecobaltous chloride promotes the reaction [HIF1A protein results in increased expression of CTGF protein]17034590
C018021cobaltous chloridecobaltous chloride promotes the reaction [TGFB1 protein results in increased expression of CTGF mRNA]17034590
C018021cobaltous chloridecobaltous chloride results in decreased expression of CTGF mRNA19320972
C018021cobaltous chloridecobaltous chloride results in increased expression of CTGF mRNA17034590|1937684
C018021cobaltous chloridecobaltous chloride results in decreased expression of CTGF mRNA24386269
D003042CocaineCocaine results in decreased expression of CTGF mRNA18000554
D003042CocaineCocaine results in decreased expression of CTGF protein18000554
C024989coenzyme Q10coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CTGF protein]27087047
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of CTGF mRNA20971185
D019327Copper SulfateCopper Sulfate affects the expression of CTGF mRNA19549813
D003474CurcuminCurcumin results in decreased expression of CTGF mRNA17965732
D003474CurcuminCurcumin results in decreased expression of CTGF protein19764552
D003474CurcuminIKBKB protein inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA]17965732
D003474CurcuminLipopolysaccharides inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA]17965732
D003474CurcuminNFKBIA protein inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA]17965732
D003474CurcuminPPARG protein promotes the reaction [Curcumin results in decreased expression of CTGF mRNA]17965732
D003474CurcuminCurcumin results in decreased expression of CTGF protein17965732
D003474CurcuminCurcumin results in decreased expression of CTGF18462866
D003513CycloheximideCycloheximide results in increased expression of CTGF mRNA19684285
D003513Cycloheximide[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CTGF mRNA19684285
D016572CyclosporineCyclosporine affects the expression of CTGF mRNA20106945
D016572Cyclosporine[Cyclosporine co-treated with Cholic Acids] affects the expression of CTGF mRNA27344345
D016572CyclosporineCyclosporine results in decreased expression of CTGF mRNA25562108|2798913
D016572CyclosporineCyclosporine results in increased expression of CTGF mRNA21632981
D016572CyclosporineCyclosporine results in increased expression of and results in increased secretion of CTGF protein21354196
D016572CyclosporineCyclosporine results in increased expression of CTGF mRNA21354196
D016572CyclosporineCyclosporine affects the expression of CTGF mRNA24971338
D016572CyclosporineCyclosporine affects the expression of CTGF protein24971338
D016572CyclosporineCyclosporine results in decreased expression of CTGF mRNA21865292
C014347decitabinedecitabine affects the expression of CTGF mRNA23300844
C014347decitabinedecitabine results in increased expression of CTGF mRNA21856257
C014347decitabinedecitabine results in decreased expression of CTGF mRNA27915011
D013759DronabinolDronabinol results in decreased expression of CTGF mRNA17578508
D003907DexamethasoneDexamethasone results in increased expression of CTGF mRNA22733784
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of CTGF mRNA"15735009
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CTGF mRNA17361019|2126653
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of CTGF mRNA21266533
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CTGF mRNA20823114
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of CTGF mRNA28962523
D002945CisplatinCisplatin affects the expression of CTGF mRNA23300844
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of CTGF mRNA27392435
D002945Cisplatin[Cisplatin co-treated with Paclitaxel] affects the expression of CTGF mRNA20705681
D002945CisplatinCisplatin results in decreased expression of CTGF mRNA27392435
D002945CisplatinCisplatin results in increased expression of CTGF mRNA21151649
C000944dicrotophosdicrotophos results in increased expression of CTGF mRNA28302478
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased expression of CTGF mRNA26924002
D004041Dietary Fats[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA18991162
D004041Dietary Fats[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein18991162
D004041Dietary FatsDietary Fats results in decreased expression of CTGF mRNA28673684
D004041Dietary FatsDietary Fats results in increased expression of CTGF mRNA18042831|2260994
D004041Dietary FatsDietary Fats results in increased expression of CTGF protein23821548|2737041
D004041Dietary FatsRALBP1 affects the reaction [Dietary Fats results in increased expression of CTGF protein]23821548
D004041Dietary Fatsrosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA]18991162
D004041Dietary Fatsrosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein]18991162
D004041Dietary Fats[Streptozocin co-treated with Dietary Fats] results in increased expression of CTGF protein24707343
D004041Dietary Fatssulforafan inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CTGF protein]24707343
D004041Dietary FatsZinc inhibits the reaction [Dietary Fats results in increased expression of CTGF protein]27370414
D004052Diethylnitrosamine"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with Diethylnitrosamine] results in increased expression of CTGF mRNA"21391223
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CTGF mRNA18164116
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CTGF mRNA19638242
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTGF mRNA"19480007
D004128DimethylnitrosamineCTGF protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]17344905
D004128DimethylnitrosamineCTGF protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 protein]17344905
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CTGF mRNA15067225|1734490
D004128DimethylnitrosamineDimethylnitrosamine results in increased expression of CTGF protein17344905
C024629dimethyl phthalatedimethyl phthalate affects the expression of CTGF mRNA26924002
D004147DioxinsDioxins affects the expression of CTGF mRNA20463971
D004237DiuronDiuron metabolite results in decreased expression of CTGF mRNA24172598
D004237DiuronDiuron results in increased expression of CTGF mRNA21551480
D004317DoxorubicinDoxorubicin affects the expression of CTGF mRNA15205334
D004317DoxorubicinDoxorubicin results in increased expression of CTGF mRNA16579640|2894005
D004317DoxorubicinDoxorubicin affects the expression of CTGF mRNA15033991
D004317DoxorubicinDoxorubicin results in increased expression of CTGF mRNA22712078|2871050
D004317DoxorubicinLovastatin inhibits the reaction [Doxorubicin results in increased expression of CTGF mRNA]22712078|2871050
D004317DoxorubicinNSC 23766 inhibits the reaction [Doxorubicin results in increased expression of CTGF mRNA]28710503
D004317Doxorubicincoenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CTGF protein]27087047
D004317DoxorubicinDoxorubicin results in increased expression of CTGF protein27087047
D004391DustDust results in increased expression of CTGF mRNA15735009
C479799(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in increased expression of CTGF mRNA15528975
C070609EMD 53998EMD 53998 analog results in increased expression of CTGF mRNA24977338
D004656EnalaprilEnalapril results in decreased expression of CTGF mRNA25037058
D004656EnalaprilEnalapril results in decreased expression of CTGF mRNA19349682
D004656EnalaprilEnalapril results in decreased expression of CTGF protein18812665|1934968
D015251EpirubicinEpirubicin results in increased expression of CTGF mRNA22712078
D015251EpirubicinLovastatin inhibits the reaction [Epirubicin results in increased expression of CTGF mRNA]22712078
C045651epigallocatechin gallateepigallocatechin gallate affects the expression of CTGF25955525
D004837EpinephrineEpinephrine results in increased expression of CTGF mRNA19300450
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of CTGF mRNA24412560
D000431Ethanolallyl sulfide inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
D000431Ethanolallyl sulfide inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D000431EthanolCAT protein inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
D000431EthanolCAT protein inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D000431Ethanol[Ethanol co-treated with Thioacetamide] results in increased expression of CTGF mRNA21863215
D000431EthanolEthanol results in increased expression of CTGF protein19280452|2896251
D000431Ethanol[Ethanol results in increased expression of CTGF protein] which results in increased abundance of Acetaldehyde19280452
D000431Ethanolfomepizole inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
D000431Ethanolfomepizole inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D000431EthanolVitamin D inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
D000431EthanolVitamin D inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D000431EthanolEthanol results in increased expression of CTGF mRNA16098508
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of CTGF mRNA17475347
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CTGF mRNA20170705|2686566
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of CTGF mRNA18936297
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CTGF mRNA20170705|2686566
C063007exoenzyme C3, Clostridium botulinum"exoenzyme C3, Clostridium botulinum inhibits the reaction [TGFB1 results in increased expression of CTGF mRNA]"15298857
C063007exoenzyme C3, Clostridium botulinum"exoenzyme C3, Clostridium botulinum inhibits the reaction [TGFB1 results in increased expression of CTGF protein]"15298857
C056164fenugreek seed mealfenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CTGF mRNA]25057273
C056164fenugreek seed mealfenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CTGF protein]25057273
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CTGF mRNA15940639
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CTGF protein15940639
D0150732-AcetylaminofluoreneIloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CTGF mRNA]15940639
D005472FluorouracilFluorouracil affects the expression of CTGF mRNA15205334
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CTGF20938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTGF gene20938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTGF mRNA20938992
C010238fomepizolefomepizole inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
C010238fomepizolefomepizole inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D004397FonofosFonofos results in increased methylation of CTGF promoter22847954
D005557FormaldehydeFormaldehyde results in increased expression of CTGF mRNA20655997|2341626
D005620Freund's AdjuvantFreund's Adjuvant results in decreased expression of CTGF mRNA20846436
D005632Fructosebetanin inhibits the reaction [Fructose results in increased expression of CTGF protein]25559852
D005632FructoseFructose results in increased expression of CTGF protein25559852
C039281furanfuran results in increased expression of CTGF mRNA27387713
C039281furanfuran results in increased expression of CTGF protein27371368
D019833GenisteinGenistein affects the expression of CTGF mRNA26865667
D019833GenisteinGenistein results in decreased expression of CTGF mRNA20884965
C002963geranylgeranyl pyrophosphategeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CTGF mRNA]]15298857
D005944GlucosamineGlucosamine analog results in increased expression of CTGF mRNA21466783
D005947Glucose2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
D005947Glucosebisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CTGF mRNA]10026205
D005947GlucoseCadmium inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
D005947GlucoseCCL2 mRNA affects the reaction [Glucose results in increased expression of CTGF protein]21367880
D005947GlucoseGlucose results in increased expression of CTGF mRNA10026205
D005947GlucoseGlucose results in increased expression of CTGF protein19369054|2136788
D005947GlucoseSB 203580 inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
D005947GlucoseZinc inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
D005947GlucoseAspirin inhibits the reaction [Glucose results in increased expression of CTGF mRNA]14586741
D005947GlucoseCTGF protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]21124846
D005947GlucoseGlucose results in increased expression of CTGF mRNA14586741
D005947GlucoseGlucose results in increased expression of CTGF protein26891083
D005947GlucoseHIF1A protein affects the reaction [Glucose results in increased expression of CTGF protein]26891083
D005947GlucoseMIR217 mRNA affects the reaction [Glucose results in increased expression of CTGF protein]26891083
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of CTGF protein]26891083
D005947GlucoseSIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of CTGF protein]]26891083
D056604Grape Seed ExtractGrape Seed Extract inhibits the reaction [Arsenic results in increased expression of CTGF mRNA]24348802
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CTGF mRNA24763279
C010176halofuginonehalofuginone results in increased expression of CTGF mRNA17180598
C005499honokiolhonokiol inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]21265825
C005499honokiolhonokiol affects the expression of CTGF mRNA21265825
C005499honokiolhonokiol inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]21265825
D017313FenretinideFenretinide results in increased expression of CTGF mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CTGF mRNA20044591|2341063
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of CTGF protein15147944
C475919hydroxytamoxifenCTGF protein affects the susceptibility to hydroxytamoxifen19153601
C475919hydroxytamoxifenGPER1 protein affects the reaction [hydroxytamoxifen results in increased expression of CTGF mRNA]19153601
C475919hydroxytamoxifenhydroxytamoxifen results in increased expression of CTGF mRNA19153601
C475919hydroxytamoxifenhydroxytamoxifen results in increased expression of CTGF protein19153601
C492448ICG 001ICG 001 results in increased expression of CTGF mRNA26191083
C036619idebenoneidebenone inhibits the reaction [Streptozocin results in increased expression of CTGF protein]28648635
D016285IloprostIloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CTGF mRNA]15940639
C016517indole-3-carbinolindole-3-carbinol affects the expression of CTGF mRNA21396975
D007213IndomethacinIndomethacin results in increased expression of CTGF mRNA12077510
C051890irinotecanirinotecan results in increased expression of CTGF mRNA20185912
D007545IsoproterenolIsoproterenol results in increased expression of CTGF mRNA20003209
D007545IsoproterenolIsoproterenol results in decreased expression of CTGF mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of CTGF mRNA24117263
D007545IsoproterenolIsoproterenol results in increased expression of CTGF protein24117263
D007545IsoproterenolQuercetin inhibits the reaction [Isoproterenol results in increased expression of CTGF mRNA]24117263
D007545IsoproterenolQuercetin inhibits the reaction [Isoproterenol results in increased expression of CTGF protein]24117263
D007545IsoproterenolRutin inhibits the reaction [Isoproterenol results in increased expression of CTGF mRNA]24117263
D007545IsoproterenolRutin inhibits the reaction [Isoproterenol results in increased expression of CTGF protein]24117263
C057531jasplakinolidejasplakinolide results in increased expression of and results in increased secretion of CTGF protein24040060
C057531jasplakinolidejasplakinolide results in increased expression of CTGF mRNA24040060|2569065
C057531jasplakinolideYAP1 protein affects the reaction [jasplakinolide results in increased expression of CTGF protein]24040060
C057531jasplakinolidejasplakinolide results in increased expression of CTGF mRNA25690654
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of CTGF mRNA27392435
C544151jinfukangjinfukang results in decreased expression of CTGF mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CTGF mRNA25961927
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of CTGF mRNA25307878|2675264
C052787kallidin, des-Arg(10)-"2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [kallidin, des-Arg(10)- results in increased expression of CTGF mRNA]"15703175
C052787kallidin, des-Arg(10)-"2',4'-dichlorobenzamil amiloride inhibits the reaction [kallidin, des-Arg(10)- results in increased expression of CTGF mRNA]"15703175
D007657Ketone BodiesKetone Bodies results in increased expression of CTGF mRNA16807920
C008261lead acetatelead acetate results in decreased expression of CTGF mRNA25270620
C045463leflunomideleflunomide results in increased expression of CTGF mRNA28988120
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [Curcumin results in decreased expression of CTGF mRNA]17965732
D008070Lipopolysaccharidesaristolochic acid I inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of CTGF protein]24412304
D008070Lipopolysaccharides[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of CTGF protein24412304
D008070Lipopolysaccharides[[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide] which results in decreased expression of CTGF protein24412304
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CTGF mRNA17965732
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CTGF protein17965732
D008148LovastatinLovastatin inhibits the reaction [Doxorubicin results in increased expression of CTGF mRNA]22712078|2871050
D008148LovastatinLovastatin inhibits the reaction [Epirubicin results in increased expression of CTGF mRNA]22712078
C485003LR-90LR-90 results in decreased expression of CTGF mRNA18317729
C485003LR-90LR-90 results in decreased expression of CTGF protein18317729
C520284Ly-364947Ly-364947 inhibits the reaction [TGFB3 protein results in increased expression of CTGF mRNA]25566828
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of CTGF mRNA24706986
C032881lysophosphatidic acidN-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CTGF mRNA]24706986
C032881lysophosphatidic acidlysophosphatidic acid results in increased expression of CTGF protein15200425
C032881lysophosphatidic acidSimvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CTGF protein]15200425
C032881lysophosphatidic acidY 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CTGF protein]15200425
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CTGF mRNA26378955
C025340manganese chloridemanganese chloride results in increased expression of CTGF mRNA17467022
D008466MechlorethamineMechlorethamine results in increased expression of CTGF mRNA26273949
D008466MechlorethamineMechlorethamine results in increased expression of CTGF protein20883710
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CTGF mRNA20823114
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of CTGF mRNA16507785
D008715MethionineCCL2 protein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA]20697377
D008715Methionine[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA18991162
D008715Methionine[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein18991162
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CTGF20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CTGF gene20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CTGF mRNA20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA20697377|2291529
D008715MethionineQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA]22915297
D008715Methioninerosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA]18991162
D008715Methioninerosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein]18991162
D008727MethotrexateCTGF mRNA results in decreased susceptibility to Methotrexate24154679
D008727MethotrexateMethotrexate results in decreased expression of CTGF mRNA17400583
D008727MethotrexateMethotrexate results in increased expression of CTGF mRNA19192274
C005219methyl cellosolvemethyl cellosolve results in increased expression of CTGF mRNA21061450
C002950methylformamidemethylformamide analog results in increased expression of CTGF mRNA17040096
C002950methylformamidemethylformamide results in increased expression of CTGF mRNA17040096
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CTGF mRNA23179753|2718838
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of CTGF mRNA"20188158
D008770MethylnitrosoureaMethylnitrosourea results in decreased expression of CTGF mRNA16525678
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of CTGF mRNA24810058
D008775MethylprednisoloneMethylprednisolone results in increased expression of CTGF mRNA19192274
D008790MetoprololMetoprolol results in increased expression of CTGF mRNA22888001
D008790MetoprololMetoprolol results in increased expression of CTGF mRNA22888001
D015735MifepristoneMifepristone results in decreased expression of CTGF mRNA25972201
C540575MK2i peptideMK2i peptide results in decreased expression of CTGF protein20864298
C540575MK2i peptideMK2i peptide inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]20864298
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of CTGF mRNA16809437
C406082monomethylarsonous acidmonomethylarsonous acid results in increased expression of CTGF protein24625837
C517284monomethyl phthalatemonomethyl phthalate affects the expression of CTGF mRNA26924002
C523799MRK 003CTGF results in decreased susceptibility to MRK 00319903844
C568376MT19c compoundMT19c compound results in decreased expression of CTGF mRNA21781307
C500085muraglitazarmuraglitazar results in decreased expression of CTGF mRNA21515302
D009151Mustard GasMustard Gas results in increased expression of CTGF mRNA16173061|2510202
D009151Mustard GasMustard Gas results in increased expression of CTGF mRNA27617619
C000589288N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamideN-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide results in decreased expression of CTGF mRNA24706986
C000589288N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamideN-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CTGF mRNA]24706986
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CTGF mRNA"22076105
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CTGF mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CTGF mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CTGF mRNA"25620056
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of CTGF mRNA25380136
C017096n-butoxyethanoln-butoxyethanol results in increased expression of CTGF mRNA19812364
C022838nickel chloridenickel chloride affects the expression of CTGF mRNA21496282
D009569Nitric Oxide[[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide] which results in decreased expression of CTGF protein24412304
C007350nitrofennitrofen results in decreased expression of CTGF mRNA20939759|2125893
C007350nitrofennitrofen results in decreased expression of CTGF protein20939759|2125893
C007350nitrofenTretinoin inhibits the reaction [nitrofen results in decreased expression of CTGF mRNA]21258935
C007350nitrofenTretinoin inhibits the reaction [nitrofen results in decreased expression of CTGF protein]21258935
C069741norcantharidinnorcantharidin results in decreased expression of CTGF mRNA18176075
C069741norcantharidinnorcantharidin results in decreased expression of CTGF protein18176075
C487513NSC 23766NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of CTGF mRNA]28710503
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of CTGF mRNA20971185
C025589ochratoxin Aochratoxin A results in decreased expression of CTGF mRNA23358140
C025589ochratoxin Aochratoxin A results in increased expression of CTGF mRNA19717638
C510784ormosil[ormosil binds to Polyethylene Glycols] which results in decreased expression of CTGF mRNA24888373
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of CTGF mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of CTGF mRNA25729387
D010100OxygenOxygen deficiency affects the expression of CTGF mRNA17193925
D010100OxygenOxygen deficiency results in increased expression of CTGF protein24657099
D010100OxygenCTGF protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]21124846
D010100OxygenOxygen results in increased expression of CTGF mRNA22911455
D017239Paclitaxel[Cisplatin co-treated with Paclitaxel] affects the expression of CTGF mRNA20705681
D000073878Palm OilPalm Oil results in increased expression of CTGF mRNA18042831
D010269Paraquat[CTGF protein co-treated with Paraquat] affects the expression of MMP2 mRNA26129822
D010269Paraquat[CTGF protein co-treated with Paraquat] affects the expression of MMP9 mRNA26129822
D010269Paraquat[CTGF protein co-treated with Paraquat] affects the expression of TIMP1 mRNA26129822
D010269Paraquat[Paraquat co-treated with TGFB1 protein] results in increased expression of CTGF mRNA26129822
D010269ParaquatParaquat results in increased expression of CTGF mRNA15728566|1676737
D010269ParaquatParaquat results in increased expression of CTGF protein16767377|2003585
D010269ParaquatSaralasin inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]20035857
D010269ParaquatSaralasin inhibits the reaction [Paraquat results in increased expression of CTGF protein]20035857
D010269ParaquatTGFB1 protein promotes the reaction [Paraquat results in increased expression of CTGF protein]27682480
D010269ParaquatTriamcinolone Acetonide promotes the reaction [Paraquat results in increased expression of CTGF mRNA]15728566
D010269ParaquatADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]25945502
D010269ParaquatParaquat results in increased expression of CTGF mRNA12595580|2594550
D010269ParaquatParaquat results in increased expression of CTGF protein26758514
D010269Paraquat"plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]"26758514
D010269Paraquat"plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CTGF protein]"26758514
D010269ParaquatParaquat results in increased expression of CTGF mRNA23433149
D010269ParaquatParaquat results in increased expression of CTGF protein23433149|2581569
D010269Paraquatprolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]23433149
D010269Paraquatprolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CTGF protein]23433149
D010278ParathionParathion results in increased methylation of CTGF promoter22847954
D052638Particulate MatterParticulate Matter results in increased expression of CTGF mRNA21708214
D010431PentoxifyllinePentoxifylline results in decreased expression of CTGF mRNA11788567
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of CTGF mRNA27153767
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of CTGF mRNA21251948
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of CTGF protein26879310
D015232Dinoprostone[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D015232Dinoprostone[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D015232Dinoprostone[MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CTGF mRNA]28434932
D010634PhenobarbitalPhenobarbital results in decreased expression of CTGF mRNA19084549
D010634PhenobarbitalPhenobarbital results in increased expression of CTGF mRNA19270015
D010656PhenylephrinePhenylephrine results in increased expression of CTGF mRNA15276029
D010656PhenylephrinePhenylephrine results in increased expression of CTGF protein15276029
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CTGF mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CTGF mRNA26272509
D010696PhloroglucinolPhloroglucinol analog inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]26054450
D010795Phthalic AcidsPhthalic Acids results in increased expression of CTGF mRNA21061450
C060836pioglitazone[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CTGF mRNA20847119
C060836pioglitazonepioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CTGF mRNA]20847119
C060836pioglitazonepioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]16484506
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CTGF mRNA19710929
C006253pirinixic acidpirinixic acid inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]19429239
C006253pirinixic acidpirinixic acid results in increased expression of CTGF mRNA18301758|2381119
D010894PiroxicamPiroxicam results in decreased expression of CTGF mRNA21858171
C442842plant extract, Puerariae Radix"plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]"26758514
C442842plant extract, Puerariae Radix"plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CTGF protein]"26758514
D010936Plant ExtractsPlant Extracts results in decreased expression of CTGF mRNA23557933
D010938Plant OilsPlant Oils results in increased expression of CTGF mRNA23370395
D011092Polyethylene Glycols[ormosil binds to Polyethylene Glycols] which results in decreased expression of CTGF mRNA24888373
D011239PrednisolonePrednisolone results in increased expression of CTGF mRNA19192274
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of CTGF mRNA28903501
D011374ProgesteroneProgesterone results in increased expression of CTGF mRNA23018184
D011374ProgesteroneCTGF gene mutant form results in increased abundance of Progesterone21868453
D011374Progesterone[CTGF gene mutant form results in increased abundance of Progesterone] which results in increased expression of CASP3 mRNA21868453
D011374ProgesteroneProgesterone affects the expression of CTGF mRNA17251523
D011374ProgesteroneProgesterone results in increased expression of CTGF mRNA22238285
C066229prolinedithiocarbamateprolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]23433149
C066229prolinedithiocarbamateprolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CTGF protein]23433149
D011441PropylthiouracilPropylthiouracil results in decreased expression of CTGF mRNA24780913
C513428pyrachlostrobinpyrachlostrobin results in increased expression of CTGF mRNA27029645
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of CTGF mRNA"21152443
D011794QuercetinQuercetin results in decreased expression of CTGF mRNA21632981
D011794QuercetinQuercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CTGF mRNA]22915297
D011794QuercetinQuercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CTGF mRNA]22989100
D011794QuercetinQuercetin inhibits the reaction [Isoproterenol results in increased expression of CTGF mRNA]24117263
D011794QuercetinQuercetin inhibits the reaction [Isoproterenol results in increased expression of CTGF protein]24117263
D011794QuercetinQuercetin inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]15573758
C059514resveratrolresveratrol results in decreased expression of CTGF mRNA23224687
C059514resveratrolresveratrol affects the expression of CTGF mRNA17875610
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of CTGF protein]26891083
C059514resveratrolSIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of CTGF protein]]26891083
C116926rofecoxibrofecoxib inhibits the reaction [Carbon Tetrachloride results in increased expression of CTGF protein]17565644
C089730rosiglitazone[rosiglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CTGF mRNA20847119
C089730rosiglitazonerosiglitazone results in decreased expression of CTGF mRNA25572481
C089730rosiglitazonerosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF mRNA]18991162
C089730rosiglitazonerosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CTGF protein]18991162
C089730rosiglitazonerosiglitazone inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]19764552
C089730rosiglitazonerosiglitazone inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]19764552
C041376rosmarinic acidrosmarinic acid inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]28789951
C041376rosmarinic acidrosmarinic acid results in decreased expression of CTGF mRNA28789951
D012431RutinRutin inhibits the reaction [Isoproterenol results in increased expression of CTGF mRNA]24117263
D012431RutinRutin inhibits the reaction [Isoproterenol results in increased expression of CTGF protein]24117263
D012504SaralasinSaralasin inhibits the reaction [Paraquat results in increased expression of CTGF mRNA]20035857
D012504SaralasinSaralasin inhibits the reaction [Paraquat results in increased expression of CTGF protein]20035857
C093642SB 203580SB 203580 analog inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]26054450
C093642SB 203580SB 203580 inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
C093642SB 203580SB 203580 results in decreased expression of CTGF protein20864298
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of CTGF"19817698
D017632Asbestos, Serpentine"TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of CTGF]"19817698
D000068677Sildenafil CitratePRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CTGF mRNA]]25139994
D000068677Sildenafil CitrateSildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CTGF mRNA]25139994
D012822Silicon DioxideSilicon Dioxide results in increased expression of CTGF mRNA25351596|2709509
D019821Simvastatingeranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CTGF mRNA]]15298857
D019821SimvastatinSimvastatin inhibits the reaction [TGFB1 results in increased expression of CTGF mRNA]15298857|1567777
D019821SimvastatinSimvastatin inhibits the reaction [TGFB1 results in increased expression of CTGF protein]15298857|1567777
D019821SimvastatinSimvastatin inhibits the reaction [Bleomycin results in increased expression of CTGF mRNA]19080365
D019821SimvastatinSimvastatin inhibits the reaction [Bleomycin results in increased expression of CTGF protein]19080365
D019821SimvastatinSimvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CTGF protein]15200425
D019821SimvastatinSimvastatin results in decreased expression of CTGF mRNA15200425|1909975
D019821SimvastatinSimvastatin results in decreased expression of CTGF protein15200425|1965965
D020123SirolimusSirolimus results in increased expression of CTGF mRNA21865292
D012906SmokeSmoke analog results in increased expression of CTGF mRNA23155386
D012906SmokeSmoke analog results in increased expression of CTGF protein23155386
D012906SmokeSmoke affects the expression of CTGF mRNA23693141
C118258SN50 peptideSN50 peptide inhibits the reaction [sunitinib results in increased expression of CTGF mRNA]26581635
C017947sodium arsenitesodium arsenite results in increased expression of CTGF mRNA12377979|2587980
C017947sodium arsenitesodium arsenite affects the expression of CTGF mRNA16507464
C017947sodium arsenitecandesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of CTGF protein]27889505
C017947sodium arsenitesodium arsenite results in increased expression of CTGF protein27889505
D012967Sodium Dodecyl SulfateSodium Dodecyl Sulfate results in decreased expression of CTGF mRNA25377654
C025399sodium tungstate(VI)sodium tungstate(VI) results in decreased expression of CTGF mRNA26164860
D053260SootSoot results in increased expression of CTGF mRNA26551751
C471405sorafenibsorafenib results in decreased expression of CTGF mRNA21360571
C060506sphingosine 1-phosphatesphingosine 1-phosphate results in increased expression of CTGF mRNA25690654
C060506sphingosine 1-phosphatesphingosine 1-phosphate results in increased expression of CTGF mRNA25690654
D013148SpironolactoneSpironolactone inhibits the reaction [Aldosterone results in increased expression of CTGF protein]17278980
C517409statticstattic inhibits the reaction [IL6 protein results in increased expression of CTGF mRNA]25740948
C517409statticstattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTGF mRNA]25740948
D013311Streptozocin[Streptozocin co-treated with Dietary Fats] results in increased expression of CTGF protein24707343
D013311StreptozocinStreptozocin results in increased expression of CTGF19657322
D013311StreptozocinStreptozocin results in increased expression of CTGF protein24967692
D013311Streptozocinsulforafan inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CTGF protein]24707343
D013311Streptozocinsulforafan inhibits the reaction [Streptozocin results in increased expression of CTGF protein]24967692
D013311StreptozocinAcetylcysteine inhibits the reaction [Streptozocin results in increased expression of CTGF protein]17270171
D013311StreptozocinAspirin inhibits the reaction [Streptozocin results in increased expression of CTGF mRNA]14586741
D013311Streptozocinfenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CTGF mRNA]25057273
D013311Streptozocinfenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CTGF protein]25057273
D013311Streptozocinidebenone inhibits the reaction [Streptozocin results in increased expression of CTGF protein]28648635
D013311StreptozocinStreptozocin results in increased expression of CTGF mRNA10026205|1458674
D013311StreptozocinStreptozocin results in increased expression of CTGF protein17270171|1936905
D013311StreptozocinXLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CTGF protein]19895808
D013311StreptozocinZinc inhibits the reaction [Streptozocin results in increased expression of CTGF protein]19369054
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CTGF mRNA26378955
C016766sulforafansulforafan inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CTGF protein]24707343
C016766sulforafansulforafan inhibits the reaction [Streptozocin results in increased expression of CTGF protein]24967692
C025462sulindac sulfidesulindac sulfide results in decreased expression of CTGF mRNA12734198
C025462sulindac sulfidesulindac sulfide results in increased expression of CTGF mRNA16184548
C473478sunitinibCarnitine inhibits the reaction [sunitinib results in increased expression of CTGF mRNA]26581635
C473478sunitinibSN50 peptide inhibits the reaction [sunitinib results in increased expression of CTGF mRNA]26581635
C473478sunitinibsunitinib results in increased expression of CTGF mRNA26581635
D013629TamoxifenTamoxifen affects the expression of CTGF mRNA20937368
D013629TamoxifenTamoxifen results in increased expression of CTGF mRNA25123088
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of CTGF mRNA15885361
C001803tempoltempol results in decreased expression of CTGF mRNA16685210
C012568terbufosterbufos results in increased methylation of CTGF promoter22847954
D013739TestosteroneTestosterone results in increased expression of CTGF mRNA15788153
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CTGF mRNA18495758
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CTGF mRNA22298810
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CTGF mRNA19684285
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CTGF mRNA19684285|2010694
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CTGF mRNA20702594|2157046
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of CTGF mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CTGF mRNA19770486|1993321
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CTGF mRNA15034205|2629044
D013749Tetrachlorodibenzodioxin2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CTGF mRNA]23196670
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CTGF mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CTGF mRNA21724226
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CTGF mRNA23196670
D013752TetracyclineTetracycline results in increased expression of CTGF mRNA16917069
D013853ThioacetamideThioacetamide results in increased expression of CTGF mRNA17997003
D013853Thioacetamide[Ethanol co-treated with Thioacetamide] results in increased expression of CTGF mRNA21863215
D013853ThioacetamideTGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of CTGF mRNA]28560358
D013853ThioacetamideThioacetamide results in increased expression of CTGF mRNA28560358
D013974ThyroxineThyroxine affects the expression of CTGF mRNA17403546
C009495titanium dioxidetitanium dioxide results in increased expression of CTGF mRNA27760801
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CTGF mRNA27865774
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CTGF mRNA27404394
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CTGF mRNA22761892
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CTGF mRNA19332661
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CTGF protein29177025
D014028Tobacco Smoke Pollutionalpha-Fetoproteins inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CTGF mRNA]15994428
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CTGF mRNA15994428
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of CTGF mRNA25729387
D019772TopotecanTopotecan results in increased expression of CTGF mRNA25729387
D014212TretinoinTretinoin results in increased expression of CTGF mRNA23830798
D014212TretinoinTretinoin inhibits the reaction [nitrofen results in decreased expression of CTGF mRNA]21258935
D014212TretinoinTretinoin inhibits the reaction [nitrofen results in decreased expression of CTGF protein]21258935
D014212TretinoinTretinoin results in increased expression of CTGF mRNA20488242|2125893
D014212TretinoinTretinoin results in increased expression of CTGF protein21258935
C032910triadimefontriadimefon results in decreased expression of CTGF mRNA26705709
D014222Triamcinolone AcetonideTriamcinolone Acetonide promotes the reaction [Paraquat results in increased expression of CTGF mRNA]15728566
C012589trichostatin Atrichostatin A results in decreased expression of CTGF mRNA15901671
C012589trichostatin Atrichostatin A results in increased expression of CTGF mRNA19606018|2670570
C012589trichostatin Atrichostatin A results in decreased expression of CTGF mRNA15901671
D014302Trinitrobenzenesulfonic Acidstattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CTGF mRNA]25740948
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of CTGF mRNA25740948
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of CTGF mRNA"26179874
C057693troglitazone[troglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CTGF mRNA20847119
C057693troglitazonetroglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CTGF mRNA]20847119
C057693troglitazonetroglitazone inhibits the reaction [TGFB1 protein results in increased expression of CTGF mRNA]17056281
C057693troglitazonetroglitazone inhibits the reaction [TGFB1 protein results in increased expression of CTGF protein]17056281|1942923
C057693troglitazonetroglitazone results in decreased expression of CTGF mRNA25572481
C057693troglitazonetroglitazone results in increased expression of CTGF mRNA19140230
D014520UrethaneUrethane results in increased expression of CTGF mRNA28818685
D014580Ursodeoxycholic AcidUrsodeoxycholic Acid results in decreased expression of CTGF mRNA15885361
D014635Valproic AcidValproic Acid results in decreased expression of CTGF mRNA15901671
D014635Valproic AcidValproic Acid affects the expression of CTGF mRNA25979313|2607246
D014635Valproic AcidValproic Acid results in decreased expression of CTGF mRNA24935251
D014635Valproic AcidValproic Acid results in increased expression of CTGF mRNA23179753|2718838
D014635Valproic AcidValproic Acid affects the expression of CTGF mRNA17292431|2607246
D014635Valproic AcidValproic Acid results in decreased expression of CTGF mRNA15901671
C066075vanadium pentoxidevanadium pentoxide results in decreased expression of CTGF mRNA17459161
C100058vanillinvanillin results in decreased expression of CTGF mRNA17178418
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of CTGF mRNA19165385
D001335Vehicle EmissionsVehicle Emissions results in increased expression of CTGF mRNA23905969
D014747VinblastineCTGF protein affects the susceptibility to Vinblastine16217747
C025643vinclozolinvinclozolin affects the expression of CTGF mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of CTGF mRNA23034163
D014750VincristineCTGF mRNA results in decreased susceptibility to Vincristine24154679
D014800VitalliumVitallium analog results in decreased expression of CTGF mRNA23825117
D014807Vitamin DVitamin D inhibits the reaction [Ethanol results in increased expression of CTGF mRNA]19280452
D014807Vitamin DVitamin D inhibits the reaction [Ethanol results in increased expression of CTGF protein]19280452
D002762CholecalciferolCholecalciferol results in decreased expression of CTGF mRNA16508948
D002762CholecalciferolCholecalciferol results in increased expression of CTGF mRNA17170073
D024483Vitamin K 3Vitamin K 3 affects the expression of CTGF mRNA20044591|2341063
C111237vorinostatvorinostat results in increased expression of CTGF mRNA27188386
C548351XLF-III-43XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CTGF protein]19895808
C108830Y 27632Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CTGF protein]15200425
C526709yishen huoxue decoctionyishen huoxue decoction results in decreased expression of CTGF mRNA17121042
D015032ZincZinc inhibits the reaction [Glucose results in increased expression of CTGF protein]19369054
D015032ZincZinc inhibits the reaction [Dietary Fats results in increased expression of CTGF protein]27370414
D015032ZincZinc inhibits the reaction [Streptozocin results in increased expression of CTGF protein]19369054

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001968fibronectin binding-IEA-  
GO:0005178integrin binding-IBA21873635  
GO:0005515protein binding-IPI16457822  
GO:0005520insulin-like growth factor binding-IEA-  
GO:0008022protein C-terminus binding-IPI9927660  
GO:0008083growth factor activity-IEA-  
GO:0008201heparin binding-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0001502cartilage condensation-IEA-  
GO:0001503ossification-IEA-  
GO:0001525angiogenesis-IEA-  
GO:0001558regulation of cell growth-IEA-  
GO:0001894tissue homeostasis-IEA-  
GO:0006367transcription initiation from RNA polymerase II promoter-TAS-  
GO:0007155cell adhesion-IBA21873635  
GO:0007160cell-matrix adhesion-IEA-  
GO:0007165signal transduction-IBA21873635  
GO:0007229integrin-mediated signaling pathway-IEA-  
GO:0007568aging-IEA-  
GO:0008284positive regulation of cell proliferation-IEA-  
GO:0008543fibroblast growth factor receptor signaling pathway-IEA-  
GO:0008544epidermis development-TAS10809757  
GO:0009611response to wounding-TAS10809757  
GO:0009749response to glucose-IEA-  
GO:0010469regulation of signaling receptor activity-IEA-  
GO:0010628positive regulation of gene expression-IEA-  
GO:0010629negative regulation of gene expression-IEA-  
GO:0016477cell migration-IEA-  
GO:0030154cell differentiation-IEA-  
GO:0030324lung development-IEA-  
GO:0032330regulation of chondrocyte differentiation-IEA-  
GO:0032355response to estradiol-IEA-  
GO:0032967positive regulation of collagen biosynthetic process-IEA-  
GO:0034059response to anoxia-IEA-  
GO:0035556intracellular signal transduction-IEA-  
GO:0035988chondrocyte proliferation-IEA-  
GO:0043200response to amino acid-IEA-  
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-IEA-  
GO:0043434response to peptide hormone-IEA-  
GO:0045597positive regulation of cell differentiation-IDA20008146  
GO:0046330positive regulation of JNK cascade-IDA20008146  
GO:0050867positive regulation of cell activation-IEA-  
GO:0051385response to mineralocorticoid-IEA-  
GO:0051496positive regulation of stress fiber assembly-IDA20008146  
GO:0060401cytosolic calcium ion transport-IEA-  
GO:0060452positive regulation of cardiac muscle contraction-IEA-  
GO:0060548negative regulation of cell death-IBA21873635  
GO:0070278extracellular matrix constituent secretion-IEA-  
GO:0070318positive regulation of G0 to G1 transition-IEA-  
GO:0070374positive regulation of ERK1 and ERK2 cascade-IDA20008146  
GO:0070542response to fatty acid-IEA-  
GO:0071897DNA biosynthetic process-IEA-  
GO:0072593reactive oxygen species metabolic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IEA-  
GO:0005801cis-Golgi network-IEA-  
GO:0005829cytosol-IEA-  
GO:0005886plasma membrane-TAS10809757  
GO:0005938cell cortex-IEA-  
GO:0031012extracellular matrix-TAS10809757  
GO:0048471perinuclear region of cytoplasm-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-2032785YAP1- and WWTR1 (TAZ)-stimulated gene expressionTAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8878159Transcriptional regulation by RUNX3TAS
R-HSA-8951671RUNX3 regulates YAP1-mediated transcriptionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20409024Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells. (2010 May)Nishioka MRespirology
21995436Cigarette smoke-induced early growth response-1 regulates the expression of the cysteine-rich 61 in human skin dermal fibroblasts. (2011 Dec)Kim JNExp Dermatol
22691361Developmental nicotine exposure results in programming of alveolar simplification and interstitial pulmonary fibrosis in adult male rats. (2012 Nov)Dasgupta CReprod Toxicol
29215705Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells. (2018 Jun)Chen PCJ Cell Physiol
25279991Maternal nicotine exposure during gestation and lactation induces kidney injury and fibrosis in rat offspring. (2015 Jan)Chen CMPediatr Res
21063506When there's smoke there's.....CCN2. (2010 Oct)Leask AJ Cell Commun Signal
18000554Gene expression in human hippocampus from cocaine abusers identifies genes which regulate extracellular matrix remodeling. (2007 Nov 14)Mash DCPLoS One
17579708Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer. (2007 Jun 20)Chen PPPLoS One
29289685TGF-beta Signaling Pathways in Different Compartments of the Lower Airways of Patients With Stable COPD. (2018 Apr)Di Stefano AChest
19966042Nicotine-induced CCN2: from smoking to periodontal fibrosis. (2010 Jan)Takeuchi HJ Dent Res
21295007Knockdown of connective tissue growth factor by plasmid-based short hairpin RNA prevented pulmonary vascular remodeling in cigarette smoke-exposed rats. (2011 Apr 1)Wang RArch Biochem Biophys
28426731Effect of genetic variation in microRNA binding site in WNT1-inducible signaling pathway protein 1 gene on oral squamous cell carcinoma susceptibility. (2017)Lau HKPLoS One
17008639Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall. (2006 Dec 15)Churg AAm J Respir Crit Care Med
25708588Expression variations of connective tissue growth factor in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease. (2015 Feb 24)Zhou SJSci Rep
29177025Acute Exposure to Cigarette Smoking Followed by Myocardial Infarction Aggravates Renal Damage in an In Vivo Mouse Model. (2017)Kobeissy FOxid Med Cell Longev
24851831Maternal nicotine exposure exacerbates neonatal hyperoxia-induced lung fibrosis in rats. (2014)Huang LTNeonatology
20970515Similar gene expression profiles in smokers and patients with moderate COPD. (2011 Feb)Llinas LPulm Pharmacol Ther