Gene: FAM78B

149297
-
family with sequence similarity 78 member B
protein-coding
1q24.1
Ensembl:ENSG00000188859 Vega:OTTHUMG00000034705 UniprotKB:Q5VT40
NC_000001.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.358e-1 (AD)  6.498e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SCN8A0.952
KCNH10.948
LHFPL40.944
PCDHAC20.942
ARHGAP200.935
TMEM178B0.933
PCDHGC50.93
MTUS20.927
NBEA0.927
RGS7BP0.923

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ROM1-0.623
COPZ2-0.614
RAB13-0.605
MYL3-0.602
HEY2-0.596
AGTRAP-0.568
RNF135-0.567
YES1-0.564
STON2-0.563
CHST14-0.557

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of FAM78B mRNA"27291303
D000082AcetaminophenAcetaminophen results in decreased expression of FAM78B mRNA29067470
C015001arsenitearsenite results in increased methylation of FAM78B promoter23974009
D001280AtrazineAtrazine results in decreased expression of FAM78B mRNA25929836
C006780bisphenol Abisphenol A results in decreased methylation of FAM78B promoter27312807
C006780bisphenol Abisphenol A results in decreased expression of FAM78B mRNA25181051
D003042CocaineCocaine results in decreased expression of FAM78B mRNA17898221
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of FAM78B mRNA23640034
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of FAM78B mRNA21266533
D002945CisplatinCisplatin results in decreased expression of FAM78B mRNA19561079
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of FAM78B mRNA25613284
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of FAM78B mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of FAM78B mRNA"25554681
D009532NickelNickel results in decreased expression of FAM78B mRNA24768652
C010272palytoxinpalytoxin results in increased expression of FAM78B mRNA26436198
D010936Plant ExtractsPlant Extracts results in decreased expression of FAM78B mRNA23557933
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of FAM78B mRNA22698814
D014212TretinoinTretinoin results in increased expression of FAM78B mRNA23724009
C011559tributyltintributyltin results in increased expression of FAM78B mRNA27614199
D014635Valproic AcidValproic Acid results in increased methylation of FAM78B gene29154799
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of FAM78B gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
25813534Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study. (2015 May)Yamada YInt J Mol Med