Gene: ABCC13

150000
ABCC13P|C21orf73|PRED6
ATP binding cassette subfamily C member 13 (pseudogene)
pseudo
21q11.2
Ensembl:ENSG00000243064 MIM:608835 UniprotKB:Q9NSE7
NC_000021.9
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.683e-1 (AD)  6.578e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2822557chr21:14298703 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PPIAL4E0.712
OR10K20.68
NR5A20.667
OR4K20.665
OR6C20.659
RPTN0.655
OR5AS10.647
DAOA0.647
OR4C120.646
KRTAP6-20.646

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MAGIX-0.357
TRIM46-0.343
BCL11A-0.34
CKMT1A-0.339
TMEM191C-0.339
MESP2-0.339
LRTM2-0.331
CHRNA4-0.331
ZNF835-0.324
THY1-0.323

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ABCC13 gene27153756
D001104ArbutinArbutin results in decreased expression of ABCC13 mRNA17103032
C006632arsenic trioxidearsenic trioxide results in decreased expression of ABCC13 mRNA20458559
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ABCC13 mRNA22316170
D004958EstradiolEstradiol results in increased expression of ABCC13 mRNA16474171
C006780bisphenol Abisphenol A results in increased expression of ABCC13 mRNA16474171
D019833GenisteinGenistein results in increased expression of ABCC13 mRNA16474171
C011890kojic acidkojic acid results in decreased expression of ABCC13 mRNA16595896
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls analog results in increased expression of ABCC13 mRNA16474171

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005524ATP binding-IEA-  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-IBA21873635  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0055085transmembrane transport-IBA21873635  
GO:0055085transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-IBA21873635  
GO:0016020membrane-IBA21873635  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal