Gene: CCDC13

152206
-
coiled-coil domain containing 13
protein-coding
3p22.1
Ensembl:ENSG00000244607 Vega:OTTHUMG00000133046 UniprotKB:Q8IYE1
NC_000003.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.555e-1 (AD)  8.114e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11915803chr3:42758799 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ATF6B0.68
SIDT20.675
THRA0.675
CHID10.667
FAAH0.666
FAM102A0.662
ILVBL0.662
PDK20.662
KIAA05560.661
TECPR20.66

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FMO3-0.409
MTRNR2L6-0.399
OR4F5-0.391
SLAMF6-0.38
MTRNR2L9-0.38
SIX1-0.379
CST7-0.373
TTLL10-AS1-0.361
OR4F29-0.358
TBX21-0.358

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC13 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC13 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC13 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC13 mRNA"27188386
C006780bisphenol Abisphenol A results in decreased expression of CCDC13 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of CCDC13 mRNA26079696
D003471CuprizoneCuprizone results in decreased expression of CCDC13 mRNA26577399|2752363
C000944dicrotophosdicrotophos results in decreased expression of CCDC13 mRNA28302478
C118739entinostatentinostat results in increased expression of CCDC13 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC13 mRNA"27188386
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CCDC13 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CCDC13 mRNA"25554681
D010416PentachlorophenolPentachlorophenol results in increased expression of CCDC13 mRNA23892564
C046012pentanalpentanal results in decreased expression of CCDC13 mRNA26079696
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCDC13 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CCDC13 mRNA26272509
D012969Sodium FluorideSodium Fluoride results in decreased expression of CCDC13 protein28918527
D012969Sodium FluorideSodium Fluoride results in increased expression of CCDC13 mRNA27862939
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CCDC13 mRNA21570461
C009495titanium dioxidetitanium dioxide affects the expression of CCDC13 mRNA23557971
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of CCDC13 mRNA29024780

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI24816561  
GO ID GO Term Qualifier Evidence PubMed
GO:0006974cellular response to DNA damage stimulus-IMP24816561  
GO:0031122cytoplasmic microtubule organization-IMP24816561  
GO:1905515non-motile cilium assembly-IDA24816561  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA-  
GO:0005813centrosome-IDA24816561  
GO:0005829cytosol-IDA-  
GO:0034451centriolar satellite-IDA24816561  
GO:0042995cell projection-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal