Gene: SLC25A48

153328
-
solute carrier family 25 member 48
protein-coding
5q31.1
Ensembl:ENSG00000145832 MIM:616150 Vega:OTTHUMG00000157007 UniprotKB:Q6ZT89
NC_000005.10
SNP Mapped
0   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.814e-1 (AD)  7.803e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FAM69C0.742
PHGDH0.703
HHATL0.683
HTRA10.666
HES60.662
SLC9A3R10.66
KCNJ100.659
SMOX0.65
PLXNB10.647
TSC22D40.64

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EMB-0.445
GCNT1-0.444
PLA2G4A-0.415
CD163L1-0.413
ACTA2-AS1-0.412
M1AP-0.412
SYNPO2-0.412
CCDC68-0.407
CCDC158-0.397
TNFRSF11A-0.386

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SLC25A48 mRNA23735875
D004958EstradiolEstradiol results in decreased expression of SLC25A48 mRNA19484750
C006780bisphenol Abisphenol A results in decreased expression of SLC25A48 mRNA25181051
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of SLC25A48 mRNA17942915
D004052DiethylnitrosamineMET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC25A48 mRNA]17942915
D017313FenretinideFenretinide results in increased expression of SLC25A48 mRNA28973697
C030272maleic acidmaleic acid results in increased expression of SLC25A48 mRNA28392987
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of SLC25A48 mRNA26011545
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of SLC25A48 mRNA22401849
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SLC25A48 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of SLC25A48 mRNA"25620056
D009538NicotineNicotine results in decreased expression of SLC25A48 mRNA23825647
C016104sodium bichromatesodium bichromate results in decreased expression of SLC25A48 mRNA24612858
D012969Sodium FluorideSodium Fluoride results in decreased expression of SLC25A48 mRNA27862939
D053260SootSoot results in increased expression of SLC25A48 mRNA26551751
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SLC25A48 mRNA26290441
D013853ThioacetamideThioacetamide results in decreased expression of SLC25A48 mRNA23411599
C009495titanium dioxidetitanium dioxide results in decreased expression of SLC25A48 mRNA23409001
D014635Valproic AcidValproic Acid results in increased expression of SLC25A48 mRNA28001369
D014635Valproic AcidValproic Acid results in increased methylation of SLC25A48 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  
GO:0015227acyl carnitine transmembrane transporter activity-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0006844acyl carnitine transport-IBA21873635  
GO:0055085transmembrane transport-IEA-  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal