Gene: CYP1A2

1544
CP12|CYPIA2|P3-450|P450(PA)
cytochrome P450 family 1 subfamily A member 2
protein-coding
15q24.1
Ensembl:ENSG00000140505 MIM:124060 Vega:OTTHUMG00000172901 UniprotKB:P05177
NG_008431.2
PubMed
CD|OD|ND|AD
232   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.685e-1 (AD)  1.821e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg01359532chr15:75045126CYP1A26.020e-21Maternal smoking in pregnancy27040690
cg01359532chr15:75045126CYP1A23.270e-23Maternal smoking in pregnancy27040690
cg01359532chr15:75045126CYP1A21.480e-25Maternal smoking in pregnancy27040690

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GPX60.79
OR7A170.763
OR12D10.748
HOXD120.686
CWH430.672
CT45A10.653
IFNA130.637
CPB20.624
ERVV-10.622
BLID0.617

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RAB41-0.321
PLA2G5-0.277
ACBD7-0.26
FBXL22-0.249
C16orf74-0.245
ZNF710-0.235
NRL-0.231
MMD2-0.229
ACOX2-0.226
PYGO1-0.223

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00951IsoniazidSmall Molecule54-85-3Approved|InvestigationalTarget
DB074532-PHENYL-4H-BENZO[H]CHROMEN-4-ONESmall MoleculeExperimentalTarget
DB11994DiacereinSmall Molecule13739-02-1Approved|InvestigationalTarget
DB00008Peginterferon alfa-2aBiotechDrug198153-51-4Approved|InvestigationalEnzyme
DB00022Peginterferon alfa-2bBiotechDrug215647-85-1ApprovedEnzyme
DB00030Insulin HumanBiotechDrug11061-68-0Approved|InvestigationalEnzyme
DB00033Interferon gamma-1bBiotechDrug98059-61-1Approved|InvestigationalEnzyme
DB00046Insulin LisproBiotechDrug133107-64-9ApprovedEnzyme
DB00047Insulin GlargineBiotechDrug160337-95-1ApprovedEnzyme
DB00071Insulin PorkBiotechDrug12584-58-6ApprovedEnzyme
DB00105Interferon Alfa-2b, RecombinantBiotechDrug98530-12-2ApprovedEnzyme
DB00170MenadioneSmall Molecule58-27-5Approved|NutraceuticalEnzyme
DB00176FluvoxamineSmall Molecule54739-18-3Approved|InvestigationalEnzyme
DB00184NicotineSmall Molecule54-11-5ApprovedEnzyme
DB00188BortezomibSmall Molecule179324-69-7Approved|InvestigationalEnzyme
DB00191PhentermineSmall Molecule122-09-8Approved|IllicitEnzyme
DB00195BetaxololSmall Molecule63659-18-7Approved|InvestigationalEnzyme
DB00196FluconazoleSmall Molecule86386-73-4Approved|InvestigationalEnzyme
DB00199ErythromycinSmall Molecule114-07-8Approved|InvestigationalEnzyme
DB00201CaffeineSmall Molecule58-08-2ApprovedEnzyme
DB00207AzithromycinSmall Molecule83905-01-5ApprovedEnzyme
DB00208TiclopidineSmall Molecule55142-85-3ApprovedEnzyme
DB00213PantoprazoleSmall Molecule102625-70-7ApprovedEnzyme
DB00215CitalopramSmall Molecule59729-33-8ApprovedEnzyme
DB00220NelfinavirSmall Molecule159989-64-7ApprovedEnzyme
DB00238NevirapineSmall Molecule129618-40-2ApprovedEnzyme
DB00246ZiprasidoneSmall Molecule146939-27-7ApprovedEnzyme
DB00257ClotrimazoleSmall Molecule23593-75-1ApprovedEnzyme
DB00261AnagrelideSmall Molecule68475-42-3ApprovedEnzyme
DB00262CarmustineSmall Molecule154-93-8Approved|InvestigationalEnzyme
DB00268RopiniroleSmall Molecule91374-21-9Approved|InvestigationalEnzyme
DB00277TheophyllineSmall Molecule58-55-9ApprovedEnzyme
DB00281LidocaineSmall Molecule137-58-6ApprovedEnzyme
DB00286Conjugated estrogensSmall Molecule12126-59-9ApprovedEnzyme
DB00296RopivacaineSmall Molecule84057-95-4ApprovedEnzyme
DB00297BupivacaineSmall Molecule38396-39-3Approved|InvestigationalEnzyme
DB00300Tenofovir disoproxilSmall Molecule201341-05-1Approved|InvestigationalEnzyme
DB00313Valproic AcidSmall Molecule99-66-1Approved|InvestigationalEnzyme
DB00315ZolmitriptanSmall Molecule139264-17-8Approved|InvestigationalEnzyme
DB00316AcetaminophenSmall Molecule103-90-2ApprovedEnzyme
DB00321AmitriptylineSmall Molecule50-48-6ApprovedEnzyme
DB00325NitroprussideSmall Molecule15078-28-1Approved|InvestigationalEnzyme
DB00333MethadoneSmall Molecule76-99-3ApprovedEnzyme
DB00334OlanzapineSmall Molecule132539-06-1Approved|InvestigationalEnzyme
DB00338OmeprazoleSmall Molecule73590-58-6Approved|InvestigationalEnzyme
DB00339PyrazinamideSmall Molecule98-96-4Approved|InvestigationalEnzyme
DB00356ChlorzoxazoneSmall Molecule95-25-0ApprovedEnzyme
DB00357AminoglutethimideSmall Molecule125-84-8Approved|InvestigationalEnzyme
DB00363ClozapineSmall Molecule5786-21-0ApprovedEnzyme
DB00365GrepafloxacinSmall Molecule119914-60-2Approved|Investigational|WithdrawnEnzyme
DB00368NorepinephrineSmall Molecule51-41-2ApprovedEnzyme
DB00370MirtazapineSmall Molecule85650-52-8ApprovedEnzyme
DB00377PalonosetronSmall Molecule135729-56-5Approved|InvestigationalEnzyme
DB00379MexiletineSmall Molecule31828-71-4Approved|InvestigationalEnzyme
DB00381AmlodipineSmall Molecule88150-42-9ApprovedEnzyme
DB00382TacrineSmall Molecule321-64-2Investigational|WithdrawnEnzyme
DB00384TriamtereneSmall Molecule396-01-0ApprovedEnzyme
DB00388PhenylephrineSmall Molecule59-42-7ApprovedEnzyme
DB00389CarbimazoleSmall Molecule22232-54-8Approved|InvestigationalEnzyme
DB00396ProgesteroneSmall Molecule57-83-0ApprovedEnzyme
DB00397PhenylpropanolamineSmall Molecule14838-15-4Approved|WithdrawnEnzyme
DB00398SorafenibSmall Molecule284461-73-0Approved|InvestigationalEnzyme
DB00400GriseofulvinSmall Molecule126-07-8Approved|InvestigationalEnzyme
DB00401NisoldipineSmall Molecule63675-72-9ApprovedEnzyme
DB00412RosiglitazoneSmall Molecule122320-73-4Approved|InvestigationalEnzyme
DB00418SecobarbitalSmall Molecule76-73-3ApprovedEnzyme
DB00420PromazineSmall Molecule58-40-2ApprovedEnzyme
DB00425ZolpidemSmall Molecule82626-48-0ApprovedEnzyme
DB00428StreptozocinSmall Molecule18883-66-4Approved|InvestigationalEnzyme
DB00435Nitric OxideSmall Molecule10102-43-9ApprovedEnzyme
DB00448LansoprazoleSmall Molecule103577-45-3Approved|InvestigationalEnzyme
DB00458ImipramineSmall Molecule50-49-7ApprovedEnzyme
DB00461NabumetoneSmall Molecule42924-53-8ApprovedEnzyme
DB00467EnoxacinSmall Molecule74011-58-8Approved|InvestigationalEnzyme
DB00468QuinineSmall Molecule130-95-0ApprovedEnzyme
DB00472FluoxetineSmall Molecule54910-89-3ApprovedEnzyme
DB00476DuloxetineSmall Molecule116539-59-4ApprovedEnzyme
DB00477ChlorpromazineSmall Molecule50-53-3Approved|InvestigationalEnzyme
DB00487PefloxacinSmall Molecule70458-92-3ApprovedEnzyme
DB00494EntacaponeSmall Molecule130929-57-6Approved|InvestigationalEnzyme
DB00499FlutamideSmall Molecule13311-84-7Approved|InvestigationalEnzyme
DB00501CimetidineSmall Molecule51481-61-9Approved|InvestigationalEnzyme
DB00502HaloperidolSmall Molecule52-86-8ApprovedEnzyme
DB00503RitonavirSmall Molecule155213-67-5Approved|InvestigationalEnzyme
DB00518AlbendazoleSmall Molecule54965-21-8ApprovedEnzyme
DB00523AlitretinoinSmall Molecule5300-03-8Approved|InvestigationalEnzyme
DB00526OxaliplatinSmall Molecule61825-94-3Approved|InvestigationalEnzyme
DB00530ErlotinibSmall Molecule183321-74-6Approved|InvestigationalEnzyme
DB00532MephenytoinSmall Molecule50-12-4Investigational|WithdrawnEnzyme
DB00533RofecoxibSmall Molecule162011-90-7Approved|Investigational|WithdrawnEnzyme
DB00537CiprofloxacinSmall Molecule85721-33-1Approved|InvestigationalEnzyme
DB00539ToremifeneSmall Molecule89778-26-7Approved|InvestigationalEnzyme
DB00540NortriptylineSmall Molecule72-69-5ApprovedEnzyme
DB00544FluorouracilSmall Molecule51-21-8ApprovedEnzyme
DB00549ZafirlukastSmall Molecule107753-78-6Approved|InvestigationalEnzyme
DB00553MethoxsalenSmall Molecule298-81-7ApprovedEnzyme
DB00564CarbamazepineSmall Molecule298-46-4Approved|InvestigationalEnzyme
DB00568CinnarizineSmall Molecule298-57-7Approved|InvestigationalEnzyme
DB00571PropranololSmall Molecule525-66-6Approved|InvestigationalEnzyme
DB00572AtropineSmall Molecule51-55-8ApprovedEnzyme
DB00575ClonidineSmall Molecule4205-90-7ApprovedEnzyme
DB00577ValaciclovirSmall Molecule124832-26-4Approved|InvestigationalEnzyme
DB00586DiclofenacSmall Molecule15307-86-5ApprovedEnzyme
DB00604CisaprideSmall Molecule81098-60-4Approved|Investigational|WithdrawnEnzyme
DB00605SulindacSmall Molecule38194-50-2Approved|InvestigationalEnzyme
DB00607NafcillinSmall Molecule147-52-4Approved|InvestigationalEnzyme
DB00615RifabutinSmall Molecule72559-06-9Approved|InvestigationalEnzyme
DB00619ImatinibSmall Molecule152459-95-5ApprovedEnzyme
DB00623FluphenazineSmall Molecule69-23-8ApprovedEnzyme
DB00625EfavirenzSmall Molecule154598-52-4Approved|InvestigationalEnzyme
DB00629GuanabenzSmall Molecule5051-62-7Approved|InvestigationalEnzyme
DB00633DexmedetomidineSmall Molecule113775-47-6ApprovedEnzyme
DB00655EstroneSmall Molecule53-16-7ApprovedEnzyme
DB00661VerapamilSmall Molecule52-53-9ApprovedEnzyme
DB00668EpinephrineSmall Molecule51-43-4ApprovedEnzyme
DB00673AprepitantSmall Molecule170729-80-3Approved|InvestigationalEnzyme
DB00675TamoxifenSmall Molecule10540-29-1ApprovedEnzyme
DB00678LosartanSmall Molecule114798-26-4ApprovedEnzyme
DB00679ThioridazineSmall Molecule50-52-2Approved|WithdrawnEnzyme
DB00682WarfarinSmall Molecule81-81-2ApprovedEnzyme
DB00694DaunorubicinSmall Molecule20830-81-3ApprovedEnzyme
DB00696ErgotamineSmall Molecule113-15-5ApprovedEnzyme
DB00697TizanidineSmall Molecule51322-75-9Approved|InvestigationalEnzyme
DB00705DelavirdineSmall Molecule136817-59-9ApprovedEnzyme
DB00714ApomorphineSmall Molecule58-00-4Approved|InvestigationalEnzyme
DB00715ParoxetineSmall Molecule61869-08-7Approved|InvestigationalEnzyme
DB00724ImiquimodSmall Molecule99011-02-6Approved|InvestigationalEnzyme
DB00730ThiabendazoleSmall Molecule148-79-8ApprovedEnzyme
DB00737MeclizineSmall Molecule569-65-3ApprovedEnzyme
DB00738PentamidineSmall Molecule100-33-4Approved|InvestigationalEnzyme
DB00740RiluzoleSmall Molecule1744-22-5Approved|InvestigationalEnzyme
DB00744ZileutonSmall Molecule111406-87-2Approved|Investigational|WithdrawnEnzyme
DB00745ModafinilSmall Molecule68693-11-8Approved|InvestigationalEnzyme
DB00752TranylcypromineSmall Molecule155-09-9Approved|InvestigationalEnzyme
DB00758ClopidogrelSmall Molecule113665-84-2ApprovedEnzyme
DB00763MethimazoleSmall Molecule60-56-0ApprovedEnzyme
DB00772MalathionSmall Molecule121-75-5Approved|InvestigationalEnzyme
DB00773EtoposideSmall Molecule33419-42-0ApprovedEnzyme
DB00778RoxithromycinSmall Molecule80214-83-1Approved|Investigational|WithdrawnEnzyme
DB00783EstradiolSmall Molecule50-28-2Approved|InvestigationalEnzyme
DB00787AciclovirSmall Molecule59277-89-3ApprovedEnzyme
DB00788NaproxenSmall Molecule22204-53-1ApprovedEnzyme
DB00794PrimidoneSmall Molecule125-33-7ApprovedEnzyme
DB00806PentoxifyllineSmall Molecule6493-05-6Approved|InvestigationalEnzyme
DB00818PropofolSmall Molecule2078-54-8Approved|InvestigationalEnzyme
DB00822DisulfiramSmall Molecule97-77-8ApprovedEnzyme
DB00829DiazepamSmall Molecule439-14-5Approved|Illicit|InvestigationalEnzyme
DB00831TrifluoperazineSmall Molecule117-89-5Approved|InvestigationalEnzyme
DB00834MifepristoneSmall Molecule84371-65-3Approved|InvestigationalEnzyme
DB00850PerphenazineSmall Molecule58-39-9ApprovedEnzyme
DB00851DacarbazineSmall Molecule4342-03-4Approved|InvestigationalEnzyme
DB00857TerbinafineSmall Molecule91161-71-6Approved|InvestigationalEnzyme
DB00863RanitidineSmall Molecule66357-35-5ApprovedEnzyme
DB00882ClomifeneSmall Molecule911-45-5Approved|InvestigationalEnzyme
DB00898EthanolSmall Molecule64-17-5ApprovedEnzyme
DB00904OndansetronSmall Molecule99614-02-5ApprovedEnzyme
DB00908QuinidineSmall Molecule56-54-2Approved|InvestigationalEnzyme
DB00917DinoprostoneSmall Molecule363-24-6ApprovedEnzyme
DB00918AlmotriptanSmall Molecule154323-57-6Approved|InvestigationalEnzyme
DB00921BuprenorphineSmall Molecule52485-79-7Approved|Illicit|InvestigationalEnzyme
DB00924CyclobenzaprineSmall Molecule303-53-7ApprovedEnzyme
DB00934MaprotilineSmall Molecule10262-69-8Approved|InvestigationalEnzyme
DB00951IsoniazidSmall Molecule54-85-3Approved|InvestigationalEnzyme
DB00953RizatriptanSmall Molecule144034-80-0ApprovedEnzyme
DB00967DesloratadineSmall Molecule100643-71-8Approved|InvestigationalEnzyme
DB00969AlosetronSmall Molecule122852-42-0Approved|WithdrawnEnzyme
DB00972AzelastineSmall Molecule58581-89-8ApprovedEnzyme
DB00974Edetic AcidSmall Molecule60-00-4ApprovedEnzyme
DB00976TelithromycinSmall Molecule191114-48-4ApprovedEnzyme
DB00978LomefloxacinSmall Molecule98079-51-7Approved|InvestigationalEnzyme
DB00980RamelteonSmall Molecule196597-26-9Approved|InvestigationalEnzyme
DB00988DopamineSmall Molecule51-61-6ApprovedEnzyme
DB00998FrovatriptanSmall Molecule158747-02-5Approved|InvestigationalEnzyme
DB01002LevobupivacaineSmall Molecule27262-47-1Approved|InvestigationalEnzyme
DB01007TioconazoleSmall Molecule65899-73-2ApprovedEnzyme
DB01012CinacalcetSmall Molecule226256-56-0ApprovedEnzyme
DB01013Clobetasol propionateSmall Molecule25122-46-7ApprovedEnzyme
DB01026KetoconazoleSmall Molecule65277-42-1Approved|InvestigationalEnzyme
DB01028MethoxyfluraneSmall Molecule76-38-0Approved|InvestigationalEnzyme
DB01029IrbesartanSmall Molecule138402-11-6Approved|InvestigationalEnzyme
DB01037SelegilineSmall Molecule14611-51-9Approved|InvestigationalEnzyme
DB01041ThalidomideSmall Molecule50-35-1Approved|Investigational|WithdrawnEnzyme
DB01045RifampicinSmall Molecule13292-46-1ApprovedEnzyme
DB01056TocainideSmall Molecule41708-72-9ApprovedEnzyme
DB01058PraziquantelSmall Molecule55268-74-1Approved|InvestigationalEnzyme
DB01059NorfloxacinSmall Molecule70458-96-7ApprovedEnzyme
DB01065MelatoninSmall Molecule73-31-4Approved|NutraceuticalEnzyme
DB01072AtazanavirSmall Molecule198904-31-3Approved|InvestigationalEnzyme
DB01075DiphenhydramineSmall Molecule58-73-1Approved|InvestigationalEnzyme
DB01079TegaserodSmall Molecule145158-71-0Approved|Investigational|WithdrawnEnzyme
DB01087PrimaquineSmall Molecule90-34-6ApprovedEnzyme
DB01094HesperetinSmall Molecule520-33-2ApprovedEnzyme
DB01095FluvastatinSmall Molecule93957-54-1ApprovedEnzyme
DB01097LeflunomideSmall Molecule75706-12-6Approved|InvestigationalEnzyme
DB01100PimozideSmall Molecule2062-78-4ApprovedEnzyme
DB01104SertralineSmall Molecule79617-96-2ApprovedEnzyme
DB01110MiconazoleSmall Molecule22916-47-8Approved|InvestigationalEnzyme
DB01115NifedipineSmall Molecule21829-25-4ApprovedEnzyme
DB01118AmiodaroneSmall Molecule1951-25-3Approved|InvestigationalEnzyme
DB01129RabeprazoleSmall Molecule117976-89-3Approved|InvestigationalEnzyme
DB01131ProguanilSmall Molecule500-92-5ApprovedEnzyme
DB01136CarvedilolSmall Molecule72956-09-3Approved|InvestigationalEnzyme
DB01137LevofloxacinSmall Molecule100986-85-4Approved|InvestigationalEnzyme
DB01142DoxepinSmall Molecule1668-19-5Approved|InvestigationalEnzyme
DB01149NefazodoneSmall Molecule83366-66-9Approved|WithdrawnEnzyme
DB01151DesipramineSmall Molecule50-47-5Approved|InvestigationalEnzyme
DB01156BupropionSmall Molecule34911-55-2ApprovedEnzyme
DB01165OfloxacinSmall Molecule82419-36-1ApprovedEnzyme
DB01166CilostazolSmall Molecule73963-72-1Approved|InvestigationalEnzyme
DB01171MoclobemideSmall Molecule71320-77-9Approved|InvestigationalEnzyme
DB01173OrphenadrineSmall Molecule83-98-7ApprovedEnzyme
DB01174PhenobarbitalSmall Molecule50-06-6Approved|InvestigationalEnzyme
DB01182PropafenoneSmall Molecule54063-53-5ApprovedEnzyme
DB01184DomperidoneSmall Molecule57808-66-9Approved|InvestigationalEnzyme
DB01191DexfenfluramineSmall Molecule3239-44-9Approved|Illicit|Investigational|WithdrawnEnzyme
DB01200BromocriptineSmall Molecule25614-03-3Approved|InvestigationalEnzyme
DB01211ClarithromycinSmall Molecule81103-11-9ApprovedEnzyme
DB01217AnastrozoleSmall Molecule120511-73-1Approved|InvestigationalEnzyme
DB01223AminophyllineSmall Molecule317-34-0ApprovedEnzyme
DB01241GemfibrozilSmall Molecule25812-30-0ApprovedEnzyme
DB01242ClomipramineSmall Molecule303-49-1Approved|InvestigationalEnzyme
DB01254DasatinibSmall Molecule302962-49-8Approved|InvestigationalEnzyme
DB01283LumiracoxibSmall Molecule220991-20-8Approved|InvestigationalEnzyme
DB01303OxtriphyllineSmall Molecule4499-40-5ApprovedEnzyme
DB01306Insulin AspartBiotechDrug116094-23-6ApprovedEnzyme
DB01307Insulin DetemirBiotechDrug169148-63-4ApprovedEnzyme
DB01309Insulin GlulisineBiotechDrug207748-29-6ApprovedEnzyme
DB01355HexobarbitalSmall Molecule56-29-1ApprovedEnzyme
DB01357MestranolSmall Molecule72-33-3ApprovedEnzyme
DB01367RasagilineSmall Molecule136236-51-6ApprovedEnzyme
DB01388MibefradilSmall Molecule116644-53-2Investigational|WithdrawnEnzyme
DB01403MethotrimeprazineSmall Molecule60-99-1Approved|InvestigationalEnzyme
DB01405TemafloxacinSmall Molecule108319-06-8WithdrawnEnzyme
DB01407ClenbuterolSmall Molecule37148-27-9Approved|InvestigationalEnzyme
DB01412TheobromineSmall Molecule83-67-0Approved|InvestigationalEnzyme
DB01418AcenocoumarolSmall Molecule152-72-7Approved|InvestigationalEnzyme
DB01424AminophenazoneSmall Molecule58-15-1Approved|WithdrawnEnzyme
DB01435AntipyrineSmall Molecule60-80-0Approved|InvestigationalEnzyme
DB01544FlunitrazepamSmall Molecule1622-62-4Approved|IllicitEnzyme
DB01558BromazepamSmall Molecule1812-30-2Approved|Illicit|InvestigationalEnzyme
DB01601LopinavirSmall Molecule192725-17-0ApprovedEnzyme
DB01621PipotiazineSmall Molecule39860-99-6Approved|InvestigationalEnzyme
DB01623ThiothixeneSmall Molecule3313-26-6ApprovedEnzyme
DB01628EtoricoxibSmall Molecule202409-33-4Approved|InvestigationalEnzyme
DB01645GenisteinSmall Molecule446-72-0InvestigationalEnzyme
DB01685TopiroxostatSmall Molecule577778-58-6Approved|InvestigationalEnzyme
DB02709ResveratrolSmall Molecule501-36-0Approved|Experimental|InvestigationalEnzyme
DB03783PhenacetinSmall Molecule62-44-2WithdrawnEnzyme
DB04574Estrone sulfateSmall Molecule481-97-0ApprovedEnzyme
DB04816DanthronSmall Molecule117-10-2Approved|Investigational|WithdrawnEnzyme
DB04841FlunarizineSmall Molecule52468-60-7ApprovedEnzyme
DB04871LorcaserinSmall Molecule616202-92-7ApprovedEnzyme
DB04920ClevidipineSmall Molecule167221-71-8Approved|InvestigationalEnzyme
DB04946IloperidoneSmall Molecule133454-47-4ApprovedEnzyme
DB05015BelinostatSmall Molecule866323-14-0Approved|InvestigationalEnzyme
DB05219CrisaboroleSmall Molecule906673-24-3Approved|InvestigationalEnzyme
DB05271RotigotineSmall Molecule99755-59-6ApprovedEnzyme
DB05708GTS-21Small Molecule148372-04-7InvestigationalEnzyme
DB05812AbirateroneSmall Molecule154229-19-3ApprovedEnzyme
DB05990Obeticholic acidSmall Molecule459789-99-2ApprovedEnzyme
DB06148MianserinSmall Molecule24219-97-4Approved|InvestigationalEnzyme
DB06210EltrombopagSmall Molecule496775-61-2ApprovedEnzyme
DB06216AsenapineSmall Molecule65576-45-6ApprovedEnzyme
DB06235VadimezanSmall MoleculeInvestigationalEnzyme
DB06264TolperisoneSmall Molecule728-88-1Approved|InvestigationalEnzyme
DB06290SimeprevirSmall Molecule923604-59-5ApprovedEnzyme
DB06292DapagliflozinSmall Molecule461432-26-8ApprovedEnzyme
DB06412OxymetholoneSmall Molecule434-07-1Approved|IllicitEnzyme
DB06413ArmodafinilSmall Molecule112111-43-0Approved|InvestigationalEnzyme
DB06442AvasimibeSmall Molecule166518-60-1InvestigationalEnzyme
DB06510MuraglitazarSmall Molecule331741-94-7InvestigationalEnzyme
DB06589PazopanibSmall Molecule444731-52-6ApprovedEnzyme
DB06594AgomelatineSmall Molecule138112-76-2Approved|InvestigationalEnzyme
DB06595MidostaurinSmall Molecule120685-11-2Approved|InvestigationalEnzyme
DB06605ApixabanSmall Molecule503612-47-3ApprovedEnzyme
DB06626AxitinibSmall Molecule319460-85-0Approved|InvestigationalEnzyme
DB06712NilvadipineSmall Molecule75530-68-6Approved|InvestigationalEnzyme
DB06732beta-NaphthoflavoneSmall Molecule6051-87-2ExperimentalEnzyme
DB06769BendamustineSmall Molecule16506-27-7Approved|InvestigationalEnzyme
DB06770Benzyl alcoholSmall Molecule100-51-6ApprovedEnzyme
DB06774CapsaicinSmall Molecule404-86-4ApprovedEnzyme
DB06803NiclosamideSmall Molecule50-65-7Approved|InvestigationalEnzyme
DB06819Phenylbutyric acidSmall Molecule1821-12-1Approved|InvestigationalEnzyme
DB06820SulconazoleSmall Molecule61318-90-9ApprovedEnzyme
DB08864RilpivirineSmall Molecule500287-72-9ApprovedEnzyme
DB08867UlipristalSmall Molecule159811-51-5ApprovedEnzyme
DB08881VemurafenibSmall Molecule918504-65-1ApprovedEnzyme
DB08909Glycerol PhenylbutyrateSmall Molecule611168-24-2ApprovedEnzyme
DB08910PomalidomideSmall Molecule19171-19-8ApprovedEnzyme
DB09061CannabidiolSmall Molecule13956-29-1Approved|InvestigationalEnzyme
DB09118StiripentolSmall Molecule49763-96-4ApprovedEnzyme
DB09120ZucapsaicinSmall Molecule25775-90-0Approved|InvestigationalEnzyme
DB09167DosulepinSmall Molecule113-53-1ApprovedEnzyme
DB09198LobeglitazoneSmall Molecule607723-33-1Approved|InvestigationalEnzyme
DB09225ZotepineSmall Molecule26615-21-4Approved|Investigational|WithdrawnEnzyme
DB09238ManidipineSmall Molecule89226-50-6Approved|InvestigationalEnzyme
DB09317Synthetic Conjugated Estrogens, ASmall Molecule-ApprovedEnzyme
DB09328VayarinSmall MoleculeApproved|InvestigationalEnzyme
DB09330OsimertinibSmall Molecule1421373-65-0ApprovedEnzyme
DB09456Insulin BeefBiotechDrug11070-73-8ApprovedEnzyme
DB09570IxazomibSmall Molecule1072833-77-2Approved|InvestigationalEnzyme
DB11638ArtenimolSmall Molecule71939-50-9Approved|InvestigationalEnzyme
DB11642PitolisantSmall Molecule362665-56-3Approved|InvestigationalEnzyme
DB11737IcotinibSmall Molecule610798-31-7Approved|InvestigationalEnzyme
DB12026VoxilaprevirSmall Molecule1535212-07-7Approved|InvestigationalEnzyme
DB12161DeutetrabenazineSmall Molecule1392826-25-3Approved|InvestigationalEnzyme
DB12332RucaparibSmall Molecule283173-50-2Approved|InvestigationalEnzyme
DB13174RheinSmall Molecule478-43-3ExperimentalEnzyme
DB13874EnasidenibSmall Molecule1446502-11-9Approved|InvestigationalEnzyme
DB13878PibrentasvirSmall Molecule1353900-92-1Approved|InvestigationalEnzyme
DB13879GlecaprevirSmall Molecule1365970-03-1Approved|InvestigationalEnzyme
DB13952Estradiol acetateSmall Molecule4245-41-4Approved|InvestigationalEnzyme
DB13953Estradiol benzoateSmall Molecule50-50-0Approved|InvestigationalEnzyme
DB13954Estradiol cypionateSmall Molecule313-06-4Approved|InvestigationalEnzyme
DB13955Estradiol dienanthateSmall Molecule7732-97-0Approved|InvestigationalEnzyme
DB13956Estradiol valerateSmall Molecule979-32-8Approved|InvestigationalEnzyme
ID Drug Name Action PubMed
C4956571,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane"CYP1A2 protein results in increased chemical synthesis of 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane"9733665
C4956571,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane"CYP1A2 protein results in increased hydroxylation of 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane"9047321
C4127911,2,3,4,6,7-hexachlorinated naphthalene"1,2,3,4,6,7-hexachlorinated naphthalene results in increased activity of CYP1A2 protein"22813907
C5756521,2,3,5,6,7-hexachloronaphthalene"1,2,3,5,6,7-hexachloronaphthalene results in increased activity of CYP1A2 protein"22813907
C0575841,2,3,7,8-pentachlorodibenzofuran"1,2,3,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA"24713691
C0514521,2,3,7,8-pentachlorodibenzo-p-dioxin"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased expression of CYP1A2 mRNA"23674508
C0186731,2,4,5-tetrachlorobenzene"1,2,4,5-tetrachlorobenzene results in increased expression of CYP1A2 protein"10696772
C0099471,2,4-trichlorobenzene"CYP1A2 protein results in increased oxidation of 1,2,4-trichlorobenzene"7747284
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased activity of CYP1A2 protein"11162773
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein"19362136
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of CYP1A2 mRNA"16269432|1725372
C0264861,2,5,6-dibenzanthracene"alyssin inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein]"19362136
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CYP1A2 mRNA"17690111
C0264861,2,5,6-dibenzanthracene"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 1,2,5,6-dibenzanthracene"8961944
C0264861,2,5,6-dibenzanthracene"CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene"8638931
C0264861,2,5,6-dibenzanthracene"[CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene] which results in increased chemical synthesis of dibenzoanthracene-1,2-dihydrodiol"8638931
C0264861,2,5,6-dibenzanthracene"[CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene] which results in increased chemical synthesis of dibenzoanthracene-3,4-dihydrodiol"8638931
C0264861,2,5,6-dibenzanthracene"EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene]"8961944
C0264861,2,5,6-dibenzanthracene"sulforafan inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein]"19362136
C0264861,2,5,6-dibenzanthracene"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 1,2,5,6-dibenzanthracene"8961944
C0264861,2,5,6-dibenzanthracene"EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene]"8961944
C0264861,2,5,6-dibenzanthracene"[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA"18711122
C0264861,2,5,6-dibenzanthracene"[1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of CYP1A2 mRNA"18711122
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CYP1A2 mRNA"18711122
C0574851-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane"1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane results in increased expression of and results in increased activity of CYP1A2 protein"26827781
C0574851-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane"1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane results in increased expression of CYP1A2 mRNA"26827781
C0353841,2-dichloroethylene"1,2-dichloroethylene affects the expression of CYP1A2 protein"9493318
C0353841,2-dichloroethylene"1,2-dichloroethylene results in decreased activity of CYP1A2 protein"9671540
C1176191,2-dimethylnaphthalene"1,2-dimethylnaphthalene results in decreased activity of CYP1A2 protein"15916432
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of CYP1A2 mRNA"19162173
C4393921-(2-methyl-4-methoxyphenyl)-4-((2-hydroxyethyl)amino)-6-trifluoromethoxy-2,3-dihydropyrrolo(3,2-c)quinoline"1-(2-methyl-4-methoxyphenyl)-4-((2-hydroxyethyl)amino)-6-trifluoromethoxy-2,3-dihydropyrrolo(3,2-c)quinoline results in decreased activity of CYP1A2 protein"15585365
C5768821-(2-trifluoromethoxyphenyl)-2-nitroethanone1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in decreased expression of CYP1A2 mRNA25596134
C5859551-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acidKetoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
C5859551-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid24120545
C5859551-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acidQuercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
C5859551-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acidThioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
C5859551-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acidTranylcypromine affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
C0374131,3-dinitropyrene"[CYP1A2 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene"11113705
C0374131,3-dinitropyrene"CYP1A2 protein affects the metabolism of 1,3-dinitropyrene"2180560
C51721513-hydroxyellipticineCYP1A2 protein results in increased chemical synthesis of 13-hydroxyellipticine22917556
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA"15764585
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NCOA6 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA]"15764585
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA"16109766|2249639
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"CTNNB1 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA]"23578392
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"MED1 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA]"16109766
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA]"22496397
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"NR1I3 protein promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CYP1A2 mRNA]"22698814
C0917651,4-dihydroxy-2-nonene"[CYP1A2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene"21766881
C0319691,4-dimethylnaphthalene"1,4-dimethylnaphthalene results in decreased activity of CYP1A2 protein"15916432
C0907681-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"CYP1A2 protein results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"29285606
C0907681-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"CYP1A2 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"29285606
C0907681-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"[CYP1A2 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene metabolite"29285606
C0907681-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"[CYP1A2 protein results in increased metabolism of N-desmethyltamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"29285606
C0907681-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"[CYP1A2 protein results in increased metabolism of Tamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"29285606
C0353421,4-naphthoquinone"1,4-naphthoquinone results in increased expression of CYP1A2 mRNA"18602459
C0353421,4-naphthoquinone"CYP1A2 protein results in increased abundance of 1,4-naphthoquinone"16243959
C0741531,4-phenylenebis(methylene)selenocyanate"1,4-phenylenebis(methylene)selenocyanate binds to and results in decreased activity of CYP1A2 protein"21732699
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]"21262253
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]"21262253
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I results in increased expression of CYP1A2 mRNA"21262253
C40193215,16-dihydrotanshinone I"15,16-dihydrotanshinone I results in increased expression of CYP1A2 protein"21262253
C40193215,16-dihydrotanshinone I"Dactinomycin inhibits the reaction [15,16-dihydrotanshinone I results in increased expression of CYP1A2 mRNA]"21262253
C40193215,16-dihydrotanshinone I"resveratrol inhibits the reaction [15,16-dihydrotanshinone I results in increased expression of CYP1A2 mRNA]"21262253
C4669211,6-dimethylnaphthalene"1,6-dimethylnaphthalene results in decreased activity of CYP1A2 protein"15916432
C0333091,6-dinitropyrene"CYP1A2 protein affects the metabolism of 1,6-dinitropyrene"2180560
C48613616-O-demethylaconitine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite21277363
C0211831,7-dimethylxanthine"CYP1A2 protein affects the metabolism of 1,7-dimethylxanthine"1302044
C0211831,7-dimethylxanthine"CYP1A2 protein results in increased chemical synthesis of 1,7-dimethylxanthine"1302044
C0211831,7-dimethylxanthine"CYP1A2 protein results in increased hydroxylation of 1,7-dimethylxanthine"15980104
C0211831,7-dimethylxanthine"CYP1A2 protein results in increased metabolism of 1,7-dimethylxanthine"19215233
C0211831,7-dimethylxanthine"[CYP1A2 protein results in increased metabolism of 1,7-dimethylxanthine] which results in increased chemical synthesis of 1-methylxanthine"19215233
C0211831,7-dimethylxanthine"[CYP1A2 protein results in increased metabolism of Caffeine] which results in increased chemical synthesis of 1,7-dimethylxanthine"19215233
C0534861,7-phenanthroline"1,7-phenanthroline inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein]"17967931
C0534861,7-phenanthroline"1,7-phenanthroline results in increased expression of CYP1A2 protein"17967931
C0333101,8-dinitropyrene"CYP1A2 protein affects the metabolism of 1,8-dinitropyrene"2180560
C0330201-aminobenzotriazole1-aminobenzotriazole results in decreased activity of CYP1A2 protein15618748
C0044821-aminopyreneCYP1A2 protein results in increased activity of 1-aminopyrene15728263
C0313371-chloronaphthalene1-chloronaphthalene results in decreased activity of CYP1A2 protein15916432
C0403451-chloropyreneCYP1A2 protein results in increased metabolism of 1-chloropyrene26252339
C4780041-hydroxy-2,3,5-trimethoxyxanthone"CYP1A2 protein results in increased metabolism of 1-hydroxy-2,3,5-trimethoxyxanthone"24380714
C0259681-methylnaphthalene1-methylnaphthalene results in decreased activity of CYP1A2 protein15916432
C0530851-methylxanthine1-methylxanthine results in decreased activity of CYP1A2 protein11465391
C0530851-methylxanthine"[CYP1A2 protein results in increased metabolism of 1,7-dimethylxanthine] which results in increased chemical synthesis of 1-methylxanthine"19215233
C0293501-naphthol1-naphthol results in decreased activity of CYP1A2 protein15916432
C0293501-naphtholCYP1A2 protein results in increased abundance of 1-naphthol16243959
C0326681-nitropyrene1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C0326681-nitropyreneCYP1A2 affects the reaction [1-nitropyrene results in increased mutagenesis of HPRT1 gene]10727902
C0326681-nitropyreneCYP1A2 affects the susceptibility to 1-nitropyrene10727902
C0326681-nitropyrene1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C0819061-O-hexyl-2,3,5-trimethylhydroquinone"1-O-hexyl-2,3,5-trimethylhydroquinone results in increased expression of CYP1A2"10503899
C0243361-phenylazo-2-naphtholCYB5A protein promotes the reaction [CYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol]17159775
C0243361-phenylazo-2-naphtholCYP1A2 protein results in increased oxidation of 1-phenylazo-2-naphthol17159775
C0243361-phenylazo-2-naphthol1-phenylazo-2-naphthol affects the expression of and affects the activity of CYP1A2 protein26845733
C0243361-phenylazo-2-naphthol[1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A2 mRNA26845733
C0243361-phenylazo-2-naphthol1-phenylazo-2-naphthol results in increased expression of CYP1A2 mRNA26845733
C0243361-phenylazo-2-naphthol[aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of CYP1A2 protein26845733
C0549192,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased expression of CYP1A2 mRNA"25542188
C5411312,2',3,3',4,4',5-heptachlorobiphenyl"2,2',3,3',4,4',5-heptachlorobiphenyl results in increased activity of CYP1A2 protein"15743714
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0297902,2',3',4,4',5-hexachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0297902,2',3',4,4',5-hexachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0297902,2',3',4,4',5-hexachlorobiphenyl"CYP1A2 results in decreased susceptibility to 2,2',3',4,4',5-hexachlorobiphenyl"21571617
C4776942,2',4,4',5-brominated diphenyl ether"2,2',4,4',5-brominated diphenyl ether results in increased expression of CYP1A2 mRNA"22331496
C4776942,2',4,4',5-brominated diphenyl ether"CYP1A2 protein results in increased oxidation of 2,2',4,4',5-brominated diphenyl ether"21673328
C4776942,2',4,4',5-brominated diphenyl ether"[CYP1A2 protein results in increased oxidation of 2,2',4,4',5-brominated diphenyl ether] which results in increased abundance of 2,2',4,4',5-brominated diphenyl ether metabolite"21673328
C5419802,2',4,6'-tetramethoxystilbene"2,2',4,6'-tetramethoxystilbene results in decreased activity of CYP1A2 protein"19463925
C0291412,2,5,7,8-pentamethyl-1-hydroxychroman"2,2,5,7,8-pentamethyl-1-hydroxychroman results in increased expression of CYP1A2 mRNA"19135037
C5206112-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"19276279
C5206112-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"19276279
C5206112-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester results in decreased activity of CYP1A2 protein"19276279
C0942102,2'-(hydroxynitrosohydrazono)bis-ethanamine"2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in decreased activity of CYP1A2 protein"15542068
C0876672,3,3',4,4',5-hexachlorobiphenyl"2,3,3',4,4',5-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
C0876672,3,3',4,4',5-hexachlorobiphenyl"2,3,3',4,4',5-hexachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0876672,3,3',4,4',5-hexachlorobiphenyl"2,3,3',4,4',5-hexachlorobiphenyl results in increased activity of CYP1A2 protein"10986007
C0876672,3,3',4,4',5-hexachlorobiphenyl"2,3,3',4,4',5-hexachlorobiphenyl results in increased expression of CYP1A2 mRNA"23674508
C0876672,3,3',4,4',5-hexachlorobiphenyl"2,3,3',4,4',5-hexachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0679402,3,3',4,4'-pentachlorobiphenyl"2,3,3',4,4'-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
C0679402,3,3',4,4'-pentachlorobiphenyl"2,3,3',4,4'-pentachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0679402,3,3',4,4'-pentachlorobiphenyl"2,3,3',4,4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0679402,3,3',4,4'-pentachlorobiphenyl"2,3,3',4,4'-pentachlorobiphenyl results in increased activity of CYP1A2 protein"10986007
C0679402,3,3',4,4'-pentachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0679402,3,3',4,4'-pentachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0679402,3,3',4,4'-pentachlorobiphenyl"CYP1A2 results in decreased susceptibility to 2,3,3',4,4'-pentachlorobiphenyl"21571617
C0679402,3,3',4,4'-pentachlorobiphenyl"2,3,3',4,4'-pentachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl results in increased activity of CYP1A2 protein"10986007
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA"23674508
C0700552,3',4,4',5-pentachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0700552,3',4,4',5-pentachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0700552,3',4,4',5-pentachlorobiphenyl"CYP1A2 results in decreased susceptibility to 2,3',4,4',5-pentachlorobiphenyl"21571617
C0700552,3',4,4',5-pentachlorobiphenyl"2,3',4,4',5-pentachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0700552,3',4,4',5-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"17342196
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased activity of CYP1A2 protein"20705892
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA"20705892
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA"23674508|2471369
C0388902,3,4,7,8-pentachlorodibenzofuran"CYP1A2 protein affects the abundance of 2,3,4,7,8-pentachlorodibenzofuran"10448125|9240455
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA"19041884
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased activity of CYP1A2 protein"17160103|2070589
C0388902,3,4,7,8-pentachlorodibenzofuran"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1A2 mRNA"20705892|2172422
C0388902,3,4,7,8-pentachlorodibenzofuran"[Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"17342195
C0104982,3,6,2',3',6'-hexachlorobiphenyl"2,3,6,2',3',6'-hexachlorobiphenyl results in decreased expression of CYP1A2 mRNA"28431184
C0104982,3,6,2',3',6'-hexachlorobiphenyl"2,3,6,2',3',6'-hexachlorobiphenyl results in increased expression of CYP1A2 protein"28431184
C0668412,3,7,8-tetrabromodibenzo-4-dioxin"2,3,7,8-tetrabromodibenzo-4-dioxin results in increased expression of and results in increased activity of CYP1A2 protein"27604104
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased activity of CYP1A2 protein"20705892
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1A2 mRNA"20705892
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1A2 mRNA"20702594|2471369
C0142112,3,7,8-tetrachlorodibenzofuran"AHR protein promotes the reaction [2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1A2 mRNA]"25768209
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1A2 mRNA"19041884
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased activity of CYP1A2 protein"20705892
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1A2 mRNA"20705892|2172422
C1004202,3-diaminotoluene"2,3-diaminotoluene results in increased expression of CYP1A2 protein"8685904
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of CYP1A2 protein"15743714
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP1A2 mRNA"21851831
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0140242,4,5,2',4',5'-hexachlorobiphenyl"CYP1A2 results in decreased susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl"21571617
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP1A2 mRNA"28433925
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"16835634
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of CYP1A2 protein"16835634
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP1A2 protein"3302669
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A2 protein"17160104
C5333422,4,6-triphenyl-1-hexene"2,4,6-triphenyl-1-hexene results in decreased expression of CYP1A2 mRNA"18560529
C0109142,4-diaminotoluene"2,4-diaminotoluene results in increased expression of CYP1A2 protein"8685904
C0094072,5,2',5'-tetrachlorobiphenyl"2,5,2',5'-tetrachlorobiphenyl results in increased expression of CYP1A2 mRNA"21703328
C0094072,5,2',5'-tetrachlorobiphenyl"CYP1A2 protein affects the susceptibility to 2,5,2',5'-tetrachlorobiphenyl"27913846
C0285192,6-dimethylnaphthalene"2,6-dimethylnaphthalene results in decreased activity of CYP1A2 protein"15916432
C0850492,7-dinitrofluorene"2,7-dinitrofluorene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
C0850492,7-dinitrofluorene"2,7-dinitrofluorene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
C5196262-amino-1,7-dimethylimidazo(4,5-g)quinoxaline"CYP1A2 protein results in increased oxidation of 2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline"22118226
C0775842-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"17279779
C0775842-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"[CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"16167840
C5225252-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA"27644595
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"9364010
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA"20307560
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with CYP1A2 protein] results in increased mutagenesis of HPRT1 gene"8625468
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [CYP1A2 protein results in decreased ethylation of Phenacetin]"8020169
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA"20307560|2081688
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"AHR mutant form inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"20816883
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"20816883
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16167840
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16167840
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"10503888|9581821
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein polymorphism results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"15110095
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"12949046|1511009
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"14725854|1594421
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased hydroxylation of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"9202738
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased hydroxylation of and results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"15310245
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17279779
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"17279779
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17279779
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine metabolite"20192249
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"1913651
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"28160022
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased oxidation of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"20192249
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2334931
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 results in increased oxidation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"10503887
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"furafylline inhibits the reaction [CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"8020169
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2023932
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in increased mutagenesis of APRT gene"2023932
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16167840
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"16167840
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17279779
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"1943715
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"1943715
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"1943715
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[1-Naphthylisothiocyanate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in decreased expression of CYP1A2 protein"15598703
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 1-Naphthylisothiocyanate] results in decreased expression of CYP1A2 protein"15598703
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA"12706856|8902619
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein"15598703|8902619
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"Caffeine promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"12706856
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 affects the oxidation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"10503887
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"15598703
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"1913651
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"8902619
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein]"8902619
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased activity of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17909072
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17909072
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17909072
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein affects the metabolism of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"2655891
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein binds to 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"9334905
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"[CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"10503888|9581821
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein mutant form results in increased metabolism of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"14744142
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased hydroxylation of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"14725854
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"28160022
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"10775323|1086195
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 results in increased metabolism of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"14744142
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"oltipraz inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline]"10775323
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"2-amino-3,4-dimethylimidazo(4,5-f)quinoline inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]"1567206
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"1544149
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"2-amino-3,4-dimethylimidazo(4,5-f)quinoline affects the expression of CYP1A2 protein"1617633
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"2-amino-3,4-dimethylimidazo(4,5-f)quinoline results in decreased activity of CYP1A2 protein"1617633
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased metabolism of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"1617633
C0369892-amino-3,4-dimethylimidazo(4,5-f)quinoline"[Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] which results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"11585058
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"9364010
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA"20307560
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased activity of CYP1A2 protein"20307560
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA"20307560|2081688
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"AHR mutant form inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]"20816883
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]"20816883
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein affects the metabolism of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2655891
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"10503888|9581821
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in decreased activity of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"20192249
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in increased hydroxylation of and results in increased activity of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"9202738
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[CYP1A2 protein results in increased metabolism of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] which results in increased chemical synthesis of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline metabolite"20192249
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[CYP1A2 protein results in increased metabolism of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] which results in increased chemical synthesis of 2-amino-4-hydroxymethyl-3,8-dimethylimidazo(4,5-f)quinoxaline"20192249
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"28160022
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in increased oxidation of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"20192249|2211822
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 results in increased activity of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2334931
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 results in increased oxidation of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"10503887
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"xanthohumol inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]"22138251
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA"23681119
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA"23681119
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[Phenobarbital co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA"23681119
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with alpha-naphthoflavone] results in increased expression of CYP1A2 protein"20448087
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 protein"20448087
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with Carbon Tetrachloride] results in increased expression of CYP1A2 mRNA"20930465
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline promotes the reaction [Carbon Tetrachloride results in decreased expression of CYP1A2 protein]"20930465
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA"12079509|1496536
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 protein"12079509|2044808
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 affects the oxidation of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"10503887
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"LTF protein inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]"12079509
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"LTF protein inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 protein]"12079509
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in increased hydroxylation of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"20448087
C5464602-amino-3-methyl-3H-imidazo(4,5-f)quinoline"2-amino-3-methyl-3H-imidazo(4,5-f)quinoline results in increased expression of CYP1A2 mRNA"23810796
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA"27644595
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"CYP1A2 protein results in increased activity of and results in increased hydroxylation of 2-amino-3-methyl-9H-pyrido(2,3-b)indole"14729582
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3-methyl-9H-pyrido(2,3-b)indole"28160022
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA"8902619
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 protein"8902619
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA]"8902619
C0178212-amino-3-methyl-9H-pyrido(2,3-b)indole"lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 protein]"8902619
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline"9364010
C0292162-amino-3-methylimidazo(4,5-f)quinoline"2-amino-3-methylimidazo(4,5-f)quinoline results in increased expression of CYP1A2 mRNA"27644595
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 protein affects the metabolism of 2-amino-3-methylimidazo(4,5-f)quinoline"2655891
C0292162-amino-3-methylimidazo(4,5-f)quinoline"[CYP1A2 protein co-treated with POR protein co-treated with OAT protein] results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline"10503888|9581821
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline"15728263
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased hydroxylation of and results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline"14725854
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline"28160022
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline"2334931
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 protein affects the susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoline"2023932
C0292162-amino-3-methylimidazo(4,5-f)quinoline"[CYP1A2 protein co-treated with 2-amino-3-methylimidazo(4,5-f)quinoline] results in increased mutagenesis of APRT gene"2023932
C0292162-amino-3-methylimidazo(4,5-f)quinoline"CYP1A2 results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline"11752233
C0292162-amino-3-methylimidazo(4,5-f)quinoline"Quercetin inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline]"11752233
C4325232-amino-3-methylimidazo(4,5-f)quinoxaline"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-3-methylimidazo(4,5-f)quinoxaline"28160022
C0352082-amino-4,6-dinitrotoluene"2-amino-4,6-dinitrotoluene affects the expression of CYP1A2 mRNA"21346803
C0854702-amino-4-hydroxymethyl-3,8-dimethylimidazo(4,5-f)quinoxaline"[CYP1A2 protein results in increased metabolism of 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] which results in increased chemical synthesis of 2-amino-4-hydroxymethyl-3,8-dimethylimidazo(4,5-f)quinoxaline"20192249
C0237852-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"CYP1A2 protein affects the metabolism of 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"2655891
C0237852-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"CYP1A2 protein results in increased hydroxylation of 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"14725854
C0237852-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole"28160022
C0178222-amino-9H-pyrido(2,3-b)indole"2-amino-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA"27644595
C0178222-amino-9H-pyrido(2,3-b)indole"[CYP1A2 protein co-treated with NAT2 gene polymorphism] promotes the reaction [2-amino-9H-pyrido(2,3-b)indole binds to and results in increased mutagenesis of HPRT1 gene]"19243127
C0178222-amino-9H-pyrido(2,3-b)indole"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-9H-pyrido(2,3-b)indole"1913651
C0178222-amino-9H-pyrido(2,3-b)indole"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 2-amino-9H-pyrido(2,3-b)indole"28160022
C0178222-amino-9H-pyrido(2,3-b)indole"[furafylline results in decreased activity of CYP1A2 protein] which results in decreased susceptibility to 2-amino-9H-pyrido(2,3-b)indole"23898916
C0178222-amino-9H-pyrido(2,3-b)indole"CYP1A2 protein results in increased metabolism of and results in increased activity of 2-amino-9H-pyrido(2,3-b)indole"1913651
C0178222-amino-9H-pyrido(2,3-b)indole"CYP1A2 protein results in increased activity of and results in increased oxidation of 2-amino-9H-pyrido(2,3-b)indole"19243127
C0178222-amino-9H-pyrido(2,3-b)indole"[CYP1A2 protein results in increased activity of and results in increased oxidation of 2-amino-9H-pyrido(2,3-b)indole] which results in increased chemical synthesis of 2-amino-9H-pyrido(2,3-b)indole metabolite"19243127
C0121772-aminofluorene2-aminofluorene inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]28119166
C0121772-aminofluorene2-aminofluorene results in decreased activity of CYP1A2 protein28119166
C0121772-aminofluoreneCYP1A2 protein affects the metabolism of 2-aminofluorene2655891
C0121772-aminofluoreneCYP1A2 results in increased activity of 2-aminofluorene11166912
C0038982-anisidineCYP1A2 protein results in increased oxidation of 2-anisidine15828049
C0038982-anisidineCYP1A2 protein results in increased oxidation of 2-anisidine16601807
C0038982-anisidine2-anisidine results in increased expression of CYP1A211409192
C0065932-anthramineCYB5A protein promotes the reaction [CYP1A2 protein results in increased activity of 2-anthramine]15728263
C0065932-anthramineCYP1A2 protein affects the metabolism of 2-anthramine2655891
C0065932-anthramineCYP1A2 protein results in increased activity of 2-anthramine15728263
C0551422-chlorobiphenyl2-chlorobiphenyl results in decreased activity of CYP1A2 protein15916432
C0047262-dichlorobenzeneCYP1A2 protein results in increased oxidation of 2-dichlorobenzene7747284
C5865422'-(glutathion-S-yl)-deschlorodiclofenac[CYP1A2 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac24246759
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[[CYP1A2 protein co-treated with CYP1A1 protein] results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"16167840
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17279779
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine metabolite"20192249
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased abundance of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"1943715
C0605332-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"[CYP1A2 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"17909072
C0530542-hydroxyemodinCYP1A2 protein results in increased chemical synthesis of 2-hydroxyemodin27989148
C0013902-hydroxyestradiolCarbaryl inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
C0013902-hydroxyestradiolChlorpyrifos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
C0013902-hydroxyestradiolCYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol16790556
C0013902-hydroxyestradiolFonofos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
C0013902-hydroxyestradiolnaphthalene inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
C0537672-methoxy-4-aminoazobenzene2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 mRNA7553614|8902619
C0537672-methoxy-4-aminoazobenzene2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 protein7553614|8902619
C0537672-methoxy-4-aminoazobenzenelead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 mRNA]8902619
C0537672-methoxy-4-aminoazobenzenelead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 protein]8902619
C0821552-methoxynaphthalene2-methoxynaphthalene results in decreased activity of CYP1A2 protein15916432
C0273842-methylnaphthalene2-methylnaphthalene results in decreased activity of CYP1A2 protein15916432
C0370732-methylquinoline2-methylquinoline results in decreased activity of CYP1A2 protein15916432
C0284052-naphthol2-naphthol results in decreased activity of CYP1A2 protein15916432
C0284052-naphtholCYP1A2 protein results in increased abundance of 2-naphthol16243959
C0053282-nitroanisole2-nitroanisole results in increased expression of CYP1A211409192
C0053282-nitroanisole2-nitroanisole results in increased expression of CYP1A2 protein16601807
C0490302-nitrofluoranthene2-nitrofluoranthene results in increased expression of CYP1A2 mRNA12107646
C5243152-oxohexyl isothiocyanate2-oxohexyl isothiocyanate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]19202560
C1096023-(2-(4-(3-chloro-2-methylphenyl)1-piperazinyl)ethyl)5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazol dihydrochloride 3.5 hydrate"3-(2-(4-(3-chloro-2-methylphenyl)1-piperazinyl)ethyl)5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazol dihydrochloride 3.5 hydrate results in decreased activity of CYP1A2 protein"16049129
C5492413-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone"[3-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA"20171196
C5492413-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone"3-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone results in increased expression of CYP1A2 mRNA"20171196
C5492413-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone"AHR protein affects the susceptibility to [3-((2,4-dimethylpyrrol-5-yl)methylidenyl)-2-indolinone results in increased expression of CYP1A2 mRNA]"20171196
C4723653-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine"3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine results in decreased activity of CYP1A2 protein"15193955
C0415253,3',4,5'-tetrahydroxystilbene"CYP1A2 protein affects the chemical synthesis of 3,3',4,5'-tetrahydroxystilbene"15276085
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in decreased activity of CYP1A2 protein"19770484
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA"15672752|1977048
C0163923,3'-diindolylmethane"[3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct"19770484
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in increased expression of CYP1A2 protein"15672752
C0163923,3'-diindolylmethane"CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane"16544949
C0163923,3'-diindolylmethane"Quercetin inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]"16544949
C0163923,3'-diindolylmethane"resveratrol inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]"16544949
C0163923,3'-diindolylmethane"3,3'-diindolylmethane results in increased expression of CYP1A2 protein"8384853
C5209453-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein]"17183067
C5209453-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"17183067
C5209453-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"17183067
C5209453-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"17183067
C0132793,4,3',4'-tetrachloroazobenzene"3,4,3',4'-tetrachloroazobenzene results in increased activity of CYP1A2 protein"2315923
C0132793,4,3',4'-tetrachloroazobenzene"3,4,3',4'-tetrachloroazobenzene results in increased expression of CYP1A2 protein"2315923
C0132803,4,3',4'-tetrachloroazoxybenzene"3,4,3',4'-tetrachloroazoxybenzene results in increased activity of CYP1A2 protein"2315923
C0132803,4,3',4'-tetrachloroazoxybenzene"3,4,3',4'-tetrachloroazoxybenzene results in increased expression of CYP1A2 protein"2315923
C0284513,4,3',4'-tetrachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1A2 mRNA"12117779|1946730
C0284513,4,3',4'-tetrachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0284513,4,3',4'-tetrachlorobiphenyl"CYP1A2 results in decreased susceptibility to 3,4,3',4'-tetrachlorobiphenyl"21571617
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]"12635099
C1047503-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole3-(4-(4-chlorophenyl-4-hydroxypiperidino)methyl)indole results in decreased expression of CYP1A2 mRNA26466350
C0273093,4,5,3',4',5'-hexachlorobiphenyl"3,4,5,3',4',5'-hexachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0273093,4,5,3',4',5'-hexachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0273093,4,5,3',4',5'-hexachlorobiphenyl"3,4,5,3',4',5'-hexachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0273093,4,5,3',4',5'-hexachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0273093,4,5,3',4',5'-hexachlorobiphenyl"CYP1A2 results in decreased susceptibility to 3,4,5,3',4',5'-hexachlorobiphenyl"21571617
C0273093,4,5,3',4',5'-hexachlorobiphenyl"3,4,5,3',4',5'-hexachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl analog results in increased expression of CYP1A2 mRNA"25068733
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA"16049271|1969266
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA"16049271
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP1A2 mRNA"28973532
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [AHR protein results in increased expression of CYP1A2]"20961953
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A2 protein"10986007
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA"20702594|2133504
C0230353,4,5,3',4'-pentachlorobiphenyl"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C0230353,4,5,3',4'-pentachlorobiphenyl"CYP1A2 results in decreased susceptibility to 3,4,5,3',4'-pentachlorobiphenyl"21571617
C0230353,4,5,3',4'-pentachlorobiphenyl"[Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA"28163111
C0230353,4,5,3',4'-pentachlorobiphenyl"[MT1 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA"26770886
C0230353,4,5,3',4'-pentachlorobiphenyl"[MT2 protein affects the susceptibility to 3,4,5,3',4'-pentachlorobiphenyl] which affects the expression of CYP1A2 mRNA"26770886
C0230353,4,5,3',4'-pentachlorobiphenyl"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"16835634
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"17342196
C0230353,4,5,3',4'-pentachlorobiphenyl"[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased activity of CYP1A2 protein"17160104
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]"12635099
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased activity of CYP1A2 protein"15659567
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP1A2 protein"16628245
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 mRNA"16049271|1969266
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1A2 protein"25530946
C0230353,4,5,3',4'-pentachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"17342195
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in increased expression of CYP1A2 mRNA"28279696
C4824923,4,5,4'-tetramethoxystilbene"3,4,5,4'-tetramethoxystilbene results in increased expression of CYP1A2 protein"28279696
C4972863,4',5-trimethoxystilbene"3,4',5-trimethoxystilbene results in increased expression of CYP1A2 mRNA"28279696
C4972863,4',5-trimethoxystilbene"3,4',5-trimethoxystilbene results in increased expression of CYP1A2 protein"28279696
C4972863,4',5-trimethoxystilbene"3,4',5-trimethoxystilbene results in decreased activity of CYP1A2 protein"16684708
C0454213,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in increased expression of CYP1A2 mRNA"23810796
C0454213,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"28160022
C0454213,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"CYP1A2 results in increased activity of 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine"2334931
C0144643,4-dichloroaniline"3,4-dichloroaniline results in increased expression of CYP1A2 mRNA"21784029
C0144643,4-dichloroaniline"3,4-dichloroaniline results in increased expression of CYP1A2 protein"21784029
C5092883',4'-dimethoxyflavone"3',4'-dimethoxyflavone affects the reaction [Tobacco Smoke Pollution analog results in increased expression of CYP1A2 mRNA]"28357125
C5092883',4'-dimethoxyflavone"3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]"26204831
C5092883',4'-dimethoxyflavone"3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]"26204831
C5092883',4'-dimethoxyflavone"3',4'-dimethoxyflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"28357125
C5092883',4'-dimethoxyflavone"3',4'-dimethoxyflavone results in decreased activity of CYP1A2 protein"21053930
C0168343,5-xylenol"CYP1A2 protein results in increased oxidation of 3,5-xylenol analog"27665777
C0168343,5-xylenol"[CYP1A2 protein results in increased oxidation of 3,5-xylenol analog] which results in increased abundance of 4-(methylsulfinyl)phenol analog"27665777
C0689233,6-dinitrobenzopyrene"CYP1A2 protein results in increased metabolism of 3,6-dinitrobenzopyrene"19393727
C0191323-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased expression of CYP1A2 mRNA"27644595
C0191323-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"28160022
C0191323-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"[[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"11999409
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"3-amino-1-methyl-5H-pyrido(4,3-b)indole results in increased expression of CYP1A2 mRNA"27644595
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"CYP1A2 protein affects the metabolism of 3-amino-1-methyl-5H-pyrido(4,3-b)indole"2655891
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 3-amino-1-methyl-5H-pyrido(4,3-b)indole"28160022
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"3-amino-1-methyl-5H-pyrido(4,3-b)indole results in increased activity of CYP1A2 protein"12744663
C0191333-amino-1-methyl-5H-pyrido(4,3-b)indole"CYP1A2 protein affects the susceptibility to 3-amino-1-methyl-5H-pyrido(4,3-b)indole"19140158
C4755683-aminobenzanthroneCYP1A2 protein results in increased oxidation of and results in increased activity of 3-aminobenzanthrone15885895
C5716313-bromomethcathinoneCYP1A2 protein results in increased metabolism of 3-bromomethcathinone27320963
C0577143-cyano-7-ethoxycoumarinClotrimazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]19858067
C0577143-cyano-7-ethoxycoumarinCYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin19858067
C0577143-cyano-7-ethoxycoumarinKetoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]19858067
C0577143-cyano-7-ethoxycoumarinNifedipine inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]19858067
C0414773-hydroxyflavone3-hydroxyflavone results in decreased activity of CYP1A2 protein21053930
C4822583'-hydroxy-genisteinCYP1A2 protein results in increased chemical synthesis of 3'-hydroxy-genistein12814970
C0811943-methylquinoline3-methylquinoline results in decreased activity of CYP1A2 protein15916432
C0336433-nitrofluoranthene3-nitrofluoranthene results in increased expression of CYP1A2 mRNA12107646
C0312853-xyleneCYP1A2 protein results in increased metabolism of 3-xylene8558417
C0312853-xylenefurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-xylene]8558417
C0312853-xylene3-xylene results in decreased activity of CYP1A2 protein8598570
C0087454,4'-bisphenol F"CYP1A2 protein results in increased glutathionylation of 4,4'-bisphenol F"23470418
C0087454,4'-bisphenol F"CYP1A2 protein results in increased hydroxylation of 4,4'-bisphenol F"23470418
C5701064,4'-cyclohexylidenebisphenol"CYP1A2 protein results in increased glutathionylation of 4,4'-cyclohexylidenebisphenol"23470418
C5701064,4'-cyclohexylidenebisphenol"CYP1A2 protein results in increased glutathionylation of 4,4'-cyclohexylidenebisphenol metabolite"23470418
C5701064,4'-cyclohexylidenebisphenol"CYP1A2 protein results in increased hydroxylation of 4,4'-cyclohexylidenebisphenol"23470418
C5830744,4'-hexafluorisopropylidene diphenol"CYP1A2 protein results in increased hydroxylation of 4,4'-hexafluorisopropylidene diphenol"23470418
C5458804,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide"CYP1A2 protein results in increased metabolism of 4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide"19697924
C1089714-amino-2-phenoxymethanesulfonanilide4-amino-2-phenoxymethanesulfonanilide promotes the reaction [CYP1A2 protein results in increased oxidation of Phenacetin]19053182
C1089714-amino-2-phenoxymethanesulfonanilideCYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide19053182
C1089714-amino-2-phenoxymethanesulfonanilidefurafylline inhibits the reaction [CYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide]19053182
C1089714-amino-2-phenoxymethanesulfonanilideQuinidine affects the reaction [CYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide]19053182
C1089714-amino-2-phenoxymethanesulfonanilideTiclopidine inhibits the reaction [CYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide]19053182
C0067574-biphenylamineCYP1A2 protein affects the metabolism of 4-biphenylamine2655891
C0067574-biphenylamineCYP1A2 protein results in increased activity of 4-biphenylamine15450435
C0067574-biphenylamineCYP1A2 protein results in increased hydroxylation of and results in increased activity of 4-biphenylamine16988941
C0067574-biphenylamine[furafylline results in decreased activity of CYP1A2 protein] which results in decreased susceptibility to 4-biphenylamine23898916
C0067574-biphenylamineCYP1A2 protein results in increased metabolism of 4-biphenylamine11376689
C0067574-biphenylamineCYP1A2 protein results in increased oxidation of 4-biphenylamine2908851
C0067574-biphenylamineCYP1A2 protein results in increased oxidation of 4-biphenylamine24857880
C0069834-chlorobiphenyl4-chlorobiphenyl results in decreased activity of CYP1A2 protein15916432
C0325384-cresolCYP1A2 protein results in increased metabolism of 4-cresol16174805
C0185114-dichlorobenzeneCYP1A2 protein results in increased oxidation of 4-dichlorobenzene7747284
C0821374-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide4-diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide results in increased expression of CYP1A2 mRNA15681896
C0275764-hydroxy-2-nonenal"[CYP1A2 protein results in increased reduction of 4-hydroxy-2-nonenal] which results in increased chemical synthesis of 1,4-dihydroxy-2-nonene"21766881
C0275764-hydroxy-2-nonenalCYP1A2 protein results in increased reduction of and results in increased oxidation of 4-hydroxy-2-nonenal21766881
C0313644-hydroxybenzyl isothiocyanate4-hydroxybenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]22664424
C0313644-hydroxybenzyl isothiocyanate4-hydroxybenzyl isothiocyanate results in increased expression of CYP1A2 mRNA22664424
C4510194-hydroxychalconeCYP1A2 protein affects the chemical synthesis of 4-hydroxychalcone15863696
C0554924-hydroxy-N-desmethyltamoxifenCYP1A2 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen29285606
C0554924-hydroxy-N-desmethyltamoxifen[CYP1A2 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen] which results in increased abundance of 4-hydroxy-N-desmethyltamoxifen metabolite29285606
C0014704-ipomeanolCYP1A2 protein results in increased activity of 4-ipomeanol15892579
C4878504'-methoxyflavone4'-methoxyflavone results in decreased activity of CYP1A2 protein21053930
C4878504'-methoxyflavone4'-methoxyflavone results in decreased activity of CYP1A2 protein19563207
C0443904-(methylsulfinyl)phenolCYP1A2 protein results in increased abundance of 4-(methylsulfinyl)phenol analog27665777
C0443904-(methylsulfinyl)phenol"[CYP1A2 protein results in increased oxidation of 3,5-xylenol analog] which results in increased abundance of 4-(methylsulfinyl)phenol analog"27665777
C0194984-nitroaniline4-nitroaniline analog results in increased activity of CYP1A2 protein9545601
C0194984-nitroaniline4-nitroaniline analog results in increased expression of CYP1A2 mRNA7553614|9545601
C0194984-nitroaniline4-nitroaniline analog results in increased expression of CYP1A2 protein7553614|9545601
C0248364-nitrophenolCYP1A2 protein results in increased hydroxylation of 4-nitrophenol11911841
C1201954-nitroquinolone-1-oxide4-nitroquinolone-1-oxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneCYP1A2 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone11774366
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneCYP1A2 protein results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone15728263
C0165834-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanoneCYP1A2 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone25221795
C4686465,12-naphthacenequinone"5,12-naphthacenequinone results in increased expression of CYP1A2 mRNA"17253728
C4830325-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-1,2-dihydro-1,6-naphthyridine"CYP1A2 protein mutant form results in decreased metabolism of 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-1,2-dihydro-1,6-naphthyridine"15564884
C4830325-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-1,2-dihydro-1,6-naphthyridine"CYP1A2 protein results in increased hydroxylation of 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-2-oxo-1,2-dihydro-1,6-naphthyridine"15564884
C5213345-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate5-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate affects the expression of CYP1A2 mRNA20932894
C0409975-bromotryptamine5-bromotryptamine analog results in decreased activity of CYP1A2 protein26599973
C0409975-bromotryptamine[5-bromotryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C5291695-chlorotryptamine5-chlorotryptamine analog results in decreased activity of CYP1A2 protein26599973
C5291695-chlorotryptamine[5-chlorotryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C0511015-fluoro-alpha-methyltryptamine5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP1A2 protein26599973
C0511015-fluoro-alpha-methyltryptamine[5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C0511015-fluoro-alpha-methyltryptamine5-fluoro-alpha-methyltryptamine results in decreased activity of CYP1A2 protein26599973
C0511015-fluoro-alpha-methyltryptamine[5-fluoro-alpha-methyltryptamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C0345365-fluorotryptamine5-fluorotryptamine analog results in decreased activity of CYP1A2 protein26599973
C0345365-fluorotryptamine[5-fluorotryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C0627115-hydroxyflavone5-hydroxyflavone results in decreased activity of CYP1A2 protein21053930
C4874135-methoxyindole5-methoxyindole results in decreased activity of CYP1A2 protein18420780
C0275525-methyltryptamine5-methyltryptamine analog results in decreased activity of CYP1A2 protein26599973
C0275525-methyltryptamine[5-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C5478585-n-butyl-pyrazolo(1,5-a)pyrimidine"5-n-butyl-pyrazolo(1,5-a)pyrimidine metabolite binds to CYP1A2 protein"19928966
C5478585-n-butyl-pyrazolo(1,5-a)pyrimidine"CYP1A2 protein results in increased glutathionylation of 5-n-butyl-pyrazolo(1,5-a)pyrimidine"19928966
C5478585-n-butyl-pyrazolo(1,5-a)pyrimidine"CYP1A2 protein results in increased glutathionylation of and results in increased activity of 5-n-butyl-pyrazolo(1,5-a)pyrimidine"19928966
C5478585-n-butyl-pyrazolo(1,5-a)pyrimidine"CYP1A2 protein results in increased metabolism of 5-n-butyl-pyrazolo(1,5-a)pyrimidine"19138062
C5478585-n-butyl-pyrazolo(1,5-a)pyrimidine"CYP1A2 protein results in increased glutathionylation of 5-n-butyl-pyrazolo(1,5-a)pyrimidine"19928966
C5478585-n-butyl-pyrazolo(1,5-a)pyrimidine"CYP1A2 protein results in increased metabolism of 5-n-butyl-pyrazolo(1,5-a)pyrimidine"19138062
C4853836,7-dihydroxyflavone"6,7-dihydroxyflavone results in decreased activity of CYP1A2 protein"21053930
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in increased expression of and results in increased activity of CYP1A2 protein26259606
C4833216-bromoindirubin-3'-oxime6-bromoindirubin-3'-oxime results in increased expression of CYP1A2 mRNA26259606
C1001016-chrysenamine6-chrysenamine results in increased expression of CYP1A2 mRNA12107646
C1001016-chrysenamineCYP1A2 protein results in increased activity of 6-chrysenamine15728263
C1118556-formylindolo(3,2-b)carbazole"6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A2 mRNA"22491429
C1118556-formylindolo(3,2-b)carbazole"[furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of AHR protein]"22491429
C0549236-methyl-1,3,8-trichlorodibenzofuran"6-methyl-1,3,8-trichlorodibenzofuran results in increased expression of CYP1A2 mRNA"19828881
C0549236-methyl-1,3,8-trichlorodibenzofuran"[furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [6-methyl-1,3,8-trichlorodibenzofuran results in increased activity of AHR protein]"22491429
C1214656-methyl-2-(phenylethynyl)pyridine6-methyl-2-(phenylethynyl)pyridine results in decreased activity of CYP1A2 protein15193955
C0346996-nitrobenzo(a)pyrene6-nitrobenzo(a)pyrene results in increased expression of CYP1A2 mRNA12107646
C0359866-nitrochrysene6-nitrochrysene results in increased expression of CYP1A2 mRNA12107646
C0776467,12-benz(a)anthraquinone"7,12-benz(a)anthraquinone results in increased expression of CYP1A2 mRNA"17253728
C0460947-chlorobenz(a)anthracene7-chlorobenz(a)anthracene results in increased expression of CYP1A2 mRNA21384493|2335814
C0460947-chlorobenz(a)anthraceneCYP1A2 protein affects the susceptibility to 7-chlorobenz(a)anthracene21384493
C0775807-(deoxyadenosin-N(6)-yl)aristolactam ICYP1A2 protein results in increased activity of 7-(deoxyadenosin-N(6)-yl)aristolactam I15386410
C0775807-(deoxyadenosin-N(6)-yl)aristolactam I[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C0775807-(deoxyadenosin-N(6)-yl)aristolactam I[CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]]21932800
C0775807-(deoxyadenosin-N(6)-yl)aristolactam ICYP1A2 protein promotes the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C0775807-(deoxyadenosin-N(6)-yl)aristolactam I[furafylline results in decreased activity of CYP1A2 protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C4056997-(deoxyadenosin-N(6)--yl)aristolactam II[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C4056997-(deoxyadenosin-N(6)--yl)aristolactam II[CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]]21932800
C4056997-(deoxyadenosin-N(6)--yl)aristolactam IICYP1A2 protein promotes the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C4056997-(deoxyadenosin-N(6)--yl)aristolactam II[furafylline results in decreased activity of CYP1A2 protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C0775797-(deoxyguanosin-N(2)-yl)aristolactam I[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C0775797-(deoxyguanosin-N(2)-yl)aristolactam I[CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]]21932800
C0775797-(deoxyguanosin-N(2)-yl)aristolactam ICYP1A2 protein promotes the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C0775797-(deoxyguanosin-N(2)-yl)aristolactam I[furafylline results in decreased activity of CYP1A2 protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C0560337-ethoxy-4-trifluoromethylcoumarinCYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin9241656
C0560337-ethoxy-4-trifluoromethylcoumarinOrphenadrine inhibits the reaction [CYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]9241656
C0134787H-dibenzo(c,g)carbazole"CYP1A2 protein affects the metabolism of and results in increased activity of 7H-dibenzo(c,g)carbazole"15534862
C0842367-hydroxy-4-trifluoromethylcoumarinCYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin9241656
C0842367-hydroxy-4-trifluoromethylcoumarinOrphenadrine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]9241656
C4298457-hydroxyflavone7-hydroxyflavone results in decreased activity of CYP1A2 protein21053930
C5562977-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine"[CYP1A2 protein co-treated with NADP co-treated with Glutathione] results in increased glutathionylation of and results in increased activity of 7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine"20825217
C0765807-methoxyresorufinCYB5A protein inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]15728263
C0765807-methoxyresorufinCYP1A2 protein binds to and affects the metabolism of 7-methoxyresorufin15659567
C0765807-methoxyresorufinCYP1A2 protein results in decreased methylation of 7-methoxyresorufin15728263
C0765807-methoxyresorufin"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]"12635099
C0765807-methoxyresorufin"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]"12635099
C0765807-methoxyresorufinCYP1A2 protein binds to and affects the metabolism of 7-methoxyresorufin15659567
C0765807-methoxyresorufinCYP1A2 protein results in decreased methylation of 7-methoxyresorufin12635099
C0765807-methoxyresorufinCYP1A2 protein results in increased metabolism of 7-methoxyresorufin22785257
C0765807-methoxyresorufinTetrachlorodibenzodioxin inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]12635099
C0366967-methyltryptamine7-methyltryptamine analog results in decreased activity of CYP1A2 protein26599973
C0366967-methyltryptamine[7-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C0389547-nitrobenzanthracene7-nitrobenzanthracene results in increased expression of CYP1A2 mRNA12107646
C0352338-hydroxyloxapineCYP1A2 results in increased chemical synthesis of 8-hydroxyloxapine21826677
C0283228-phenyltheophylline8-phenyltheophylline inhibits the reaction [CYP1A2 protein results in decreased ethylation of Phenacetin]11465391
C0283228-phenyltheophylline8-phenyltheophylline results in decreased activity of CYP1A2 protein11465391
C1197378-prenylnaringenin8-prenylnaringenin results in decreased activity of CYP1A2 protein19770484
C1197378-prenylnaringenin8-prenylnaringenin results in increased expression of CYP1A2 mRNA15672752
C4210109-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"CYP1A2 protein affects the metabolism of 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"17067997
C4210109-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"CYP1A2 protein results in increased chemical synthesis of 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"15279827
C4210109-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"CYP1A2 protein results in increased metabolism of and results in increased susceptibility to 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"28160022
C0730509-anthraldehyde[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde21766881
C0913759-phenanthrolCYP1A2 protein results in increased abundance of 9-phenanthrol27137136
C0913759-phenanthrol[CYP1A2 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol27137136
C023717acacetinacacetin results in decreased activity of CYP1A2 protein21053930
C042552acenaphtheneacenaphthene results in increased activity of CYP1A2 protein8001243
C042552acenaphthene[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA7750161
C042553acenaphthyleneCYP1A2 protein results in increased oxidation of acenaphthylene25642975
C042553acenaphthylene[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA7750161
C042553acenaphthyleneacenaphthylene results in increased activity of CYP1A2 protein10977129|8001243
C042553acenaphthyleneacenaphthylene results in increased expression of CYP1A2 mRNA8001243
C042553acenaphthyleneacenaphthylene results in increased expression of CYP1A2 protein8001243
D000074AcenocoumarolCYP1A2 protein affects the metabolism of Acenocoumarol11918509
C001969acephate[fenarimol co-treated with acephate] affects the expression of CYP1A2 protein17686559
C001969acephate[fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A2 protein17686559
D000082AcetaminophenCYP1A2 protein results in increased chemical synthesis of Acetaminophen17097115
D000082AcetaminophenCYP1A2 protein results in increased chemical synthesis of Acetaminophen12401345|1515555
D000082Acetaminophen[CYP1A2 protein results in increased metabolism of Phenacetin] which results in increased chemical synthesis of Acetaminophen19135037
D000082AcetaminophenCYP1A2 protein results in increased oxidation of Acetaminophen10811468
D000082AcetaminophenCYP1A2 results in increased metabolism of Acetaminophen20566340
D000082Acetaminophen[CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen28762043
D000082AcetaminophenGSTM1 protein inhibits the reaction [[CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen]28762043
D000082Acetaminophenobeticholic acid inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of Acetaminophen]27939613
D000082AcetaminophenAcetaminophen affects the expression of CYP1A2 mRNA17562736
D000082AcetaminophenAcetaminophen results in decreased expression of CYP1A2 mRNA15576447|1661162
D000082AcetaminophenAcetaminophen results in decreased expression of CYP1A2 protein15576447|2132937
D000082AcetaminophenAcetaminophen results in increased expression of CYP1A2 mRNA12958197|1497823
D000082AcetaminophenAcetaminophen results in increased expression of CYP1A2 protein19002106
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of CYP1A2 mRNA17585979
D000082AcetaminophenCYP1A2 protein affects the metabolism of and results in decreased abundance of Acetaminophen19679878
D000082AcetaminophenCYP1A2 protein results in increased abundance of Acetaminophen10445756
D000082AcetaminophenCYP1A2 protein results in increased metabolism of Acetaminophen10977129|1900210
D000082AcetaminophenCYP1A2 protein results in increased metabolism of and affects the susceptibility to Acetaminophen11376689
D000082AcetaminophenCYP1A2 protein results in increased susceptibility to Acetaminophen16141365|1655755
D000082AcetaminophenIL1A protein inhibits the reaction [Acetaminophen results in increased expression of CYP1A2 protein]19002106
D000082AcetaminophenNR1I2 protein affects the reaction [Acetaminophen results in increased expression of CYP1A2 mRNA]16141365
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP1A2 mRNA]17585979
D000082AcetaminophenPPARA protein affects the reaction [Acetaminophen results in increased expression of CYP1A2 mRNA]12958197
D000082AcetaminophenRXRA protein promotes the reaction [Acetaminophen results in increased expression of CYP1A2 mRNA]14978233
D000082AcetaminophenSLC13A1 protein affects the reaction [Acetaminophen results in increased expression of CYP1A2 mRNA]16729303
D000082AcetaminophenAcetaminophen affects the expression of CYP1A2 mRNA11245408|1736632
D000082AcetaminophenAcetaminophen inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D000082AcetaminophenAcetaminophen results in decreased expression of CYP1A2 mRNA12969438|2180707
D000082AcetaminophenAcetaminophen results in increased expression of CYP1A2 protein18798224
D000082AcetaminophenCholine deficiency inhibits the reaction [Acetaminophen results in increased expression of CYP1A2 protein]18798224
D000082AcetaminophenCYP1A2 protein results in increased chemical synthesis of Acetaminophen28438436
D000082Acetaminophen[CYP1A2 protein results in increased metabolism of Phenacetin] which results in increased chemical synthesis of Acetaminophen28438436
D000082Acetaminophen[Dextran Sulfate results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of Acetaminophen28438436
D000082Acetaminophen[EGF protein co-treated with HGF protein] promotes the reaction [Acetaminophen results in decreased expression of CYP1A2 mRNA]12969438
D000082AcetaminophenCYP1A2 results in increased oxidation of Acetaminophen8861779
D000082Acetaminophen[CYP1A2 results in increased oxidation of Acetaminophen] which results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine8861779
D000096AcetoneAcetone promotes the reaction [Toluene results in increased expression of CYP1A2 protein]8996725
D000111Acetylcysteine[CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite27989148
D000111Acetylcysteine[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]21424224
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]22129741
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]23159886
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]23159886
D000157Aconitine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in increased chemical synthesis of Aconitine metabolite21277363
D000166AcridinesAcridines analog inhibits the reaction [CYP1A2 protein results in increased oxidation of vadimezan]16120190
D000166AcridinesAcridines analog results in decreased activity of CYP1A2 protein16120190
C560978aegeline[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA28843594
C016601afimoxifeneCYP1A2 protein results in increased metabolism of afimoxifene29285606
C016601afimoxifene[CYP1A2 protein results in increased metabolism of afimoxifene] which results in increased abundance of afimoxifene metabolite29285606
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CYP1A2 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CYP1A2 mRNA21994236
D016604Aflatoxin B1[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Aflatoxin B123397584
D016604Aflatoxin B1CYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]21907773
D016604Aflatoxin B1CYP1A2 protein results in increased activity of Aflatoxin B115988000
D016604Aflatoxin B1CYP1A2 protein results in increased metabolism of Aflatoxin B122743290
D016604Aflatoxin B1"[CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin B1-2,3-oxide"20707407
D016604Aflatoxin B1[CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of Aflatoxin M120707407
D016604Aflatoxin B1CYP1A2 protein results in increased metabolism of and results in increased activity of Aflatoxin B120707407
D016604Aflatoxin B1CYP1A2 protein results in increased susceptibility to Aflatoxin B111189750|2791384
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CYP1A2 mRNA19770486
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CYP1A2 mRNA26260870
D016604Aflatoxin B1CYP1A2 protein results in increased susceptibility to Aflatoxin B122743290
C006426aflatoxin B1-2,3-oxide"[CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin B1-2,3-oxide"20707407
C006426aflatoxin B1-2,3-oxide"CYP1A2 protein results in increased chemical synthesis of aflatoxin B1-2,3-oxide"19146867
C072611aflatoxin B1-DNA adduct"[3,3'-diindolylmethane results in increased expression of CYP1A2 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct"19770484
C072611aflatoxin B1-DNA adductCYP1A2 protein results in increased chemical synthesis of aflatoxin B1-DNA adduct22743290
C027955aflatoxin G1CYP1A2 protein results in increased susceptibility to aflatoxin G111189750
D016607Aflatoxin M1[CYP1A2 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of Aflatoxin M120707407
D016607Aflatoxin M1CYP1A2 protein results in increased chemical synthesis of Aflatoxin M119146867
C000188alachloralachlor results in increased expression of CYP1A2 protein11850968
D015766AlbendazoleAlbendazole results in increased expression of CYP1A2 mRNA12451431
D015766AlbendazoleCYP1A2 protein affects the metabolism of Albendazole12920490
D015766AlbendazoleAlbendazole results in increased expression of and results in increased activity of CYP1A2 protein15766946
D015766AlbendazoleCYP1A2 protein affects the metabolism of and results in decreased activity of Albendazole15766946
C010078alizarinalizarin results in decreased activity of CYP1A2 protein12379470
C109505allocryptopineallocryptopine results in increased expression of CYP1A2 mRNA21419197
C006463allyl alcoholallyl alcohol results in decreased expression of CYP1A2 protein10547960
C077207allyl methyl sulfideallyl methyl sulfide results in increased expression of CYP1A2 protein16000231
C038491allyl sulfideallyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP1A2 protein]23494807
C038491allyl sulfideallyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP1A2 mRNA]23494807
C038491allyl sulfideallyl sulfide results in increased expression of CYP1A2 mRNA19695238|8849338
C409045almotriptanCYP1A2 protein results in decreased methylation of almotriptan12642466
C518327aloe emodinaloe emodin results in decreased activity of CYP1A2 protein27633141
C010177alpha-hederinalpha-hederin results in decreased activity of CYP1A2 protein9861456
C010177alpha-hederinalpha-hederin results in decreased expression of CYP1A2 mRNA9861456
D017962alpha-Linolenic Acidalpha-Linolenic Acid results in decreased activity of CYP1A2 protein16978661
C011512alpha-naphthoflavonealpha-naphthoflavone binds to and results in decreased activity of CYP1A2 protein28887089
C011512alpha-naphthoflavone"alpha-naphthoflavone inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"20816883
C011512alpha-naphthoflavone"alpha-naphthoflavone inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]"20816883
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C011512alpha-naphthoflavonealpha-naphthoflavone results in decreased activity of CYP1A2 protein15306208|1576691
C011512alpha-naphthoflavone[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C011512alpha-naphthoflavonealpha-naphthoflavone results in increased expression of CYP1A2 mRNA19828881
C011512alpha-naphthoflavonealpha-naphthoflavone results in increased expression of CYP1A2 protein28887089
C011512alpha-naphthoflavoneCYP1A2 protein affects the metabolism of alpha-naphthoflavone2180560
C011512alpha-naphthoflavoneCYP1A2 protein binds to alpha-naphthoflavone27966929
C011512alpha-naphthoflavoneCYP1A2 protein results in increased metabolism of alpha-naphthoflavone17702393
C011512alpha-naphthoflavonealpha-naphthoflavone results in decreased activity of CYP1A2 protein15766918
C011512alpha-naphthoflavonealpha-naphthoflavone results in decreased activity of CYP1A2 protein15766918
C011512alpha-naphthoflavone[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C011512alpha-naphthoflavone[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde21766881
C011512alpha-naphthoflavone"[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with alpha-naphthoflavone] results in increased expression of CYP1A2 protein"20448087
C011512alpha-naphthoflavonealpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C011512alpha-naphthoflavonealpha-naphthoflavone results in increased expression of CYP1A2 protein20448087
C011512alpha-naphthoflavonealpha-naphthoflavone results in decreased activity of CYP1A2 protein10828259|1550751
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]26102010
D024502alpha-Tocopherolalpha-Tocopherol results in increased activity of CYP1A2 protein15665910
C524316alyssin"alyssin inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein]"19362136
C524316alyssinalyssin inhibits the reaction [anthracene results in increased activity of CYP1A2 protein]19362136
C524316alyssinalyssin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]19202560
C100057ametryneCYP1A2 protein results in increased metabolism of ametryne8971136
C100057ametrynePOR protein promotes the reaction [CYP1A2 protein results in increased metabolism of ametryne]8971136
D000588AminesCYP1A2 protein affects the metabolism of and results in increased activity of Amines12505289
D000588AminesCYP1A2 protein results in increased hydroxylation of and affects the metabolism of Amines15613766
D009762o-Aminoazotolueneo-Aminoazotoluene results in increased activity of CYP1A2 protein15863256
D009762o-Aminoazotolueneo-Aminoazotoluene results in increased expression of CYP1A2 mRNA10887293|1456268
D0150812-NaphthylamineCYP1A2 protein results in increased activity of 2-Naphthylamine15450435
D000634AminoquinolinesAminoquinolines inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D000634AminoquinolinesAminoquinolines results in decreased activity of CYP1A2 protein18563832
D000634AminoquinolinesAminoquinolines inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D000638AmiodaroneAmiodarone results in decreased activity of CYP1A2 protein16449812|2659997
D000638Amiodarone[Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D000638AmiodaroneCYP1A2 protein results in decreased susceptibility to Amiodarone26477383
C014983amitrazamitraz results in increased expression of CYP1A2 protein15350676
D000639AmitriptylineAmitriptyline results in increased metabolism of CYP1A2 protein18359012
D000639Amitriptyline[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Amitriptyline23397584
D000639AmitriptylineCYP1A2 protein results in increased metabolism of Amitriptyline27320963
C006566amitriptyline N-oxideCYP1A2 protein results in increased abundance of amitriptyline N-oxide27320963
D000655AmodiaquineAmodiaquine results in decreased activity of CYP1A2 protein11124226
D000655Amodiaquine[Gemfibrozil results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine26599973
D000655Amodiaquine[Trimethoprim results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine26599973
D000661AmphetamineCYP1A2 protein affects the chemical synthesis of Amphetamine15294457
C030419andrographolideandrographolide results in decreased expression of CYP1A2 mRNA19041297
C030419andrographolide[andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1A2 mRNA17825862
C030419andrographolide[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA19737545
C030419andrographolideandrographolide results in increased expression of CYP1A2 mRNA17825862
C030419andrographolideandrographolide affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline]20096675
C030419andrographolideandrographolide results in increased expression of CYP1A2 mRNA19041297
D000737AndrostenolsAndrostenols results in decreased expression of CYP1A2 mRNA17962186
C011659angelicinangelicin results in increased expression of CYP1A2 protein18692084
C023650anilineCYP1A2 protein affects the metabolism of [norharman co-treated with aniline]15279827
C023650anilineaniline analog results in increased activity of CYP1A2 protein16639589
C023650anilineaniline analog results in increased expression of CYP1A2 mRNA16639589
C023650anilineaniline analog results in increased expression of CYP1A2 protein16639589
C034020anthracenealyssin inhibits the reaction [anthracene results in increased activity of CYP1A2 protein]19362136
C034020anthraceneanthracene results in increased activity of CYP1A2 protein19362136
C034020anthracenesulforafan inhibits the reaction [anthracene results in increased activity of CYP1A2 protein]19362136
C034020anthracene[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA7750161
C034020anthraceneanthracene results in increased activity of CYP1A2 protein8001243
D018943AnthracyclinesAnthracyclines results in decreased activity of CYP1A2 protein15588138
D047310ApigeninApigenin results in decreased activity of CYP1A2 protein20806393|2105393
D016718Arachidonic AcidArachidonic Acid results in decreased activity of CYP1A2 protein16978661
D016718Arachidonic AcidCYP1A2 protein results in increased metabolism of Arachidonic Acid12675279
D016718Arachidonic AcidCYP1A2 protein results in increased metabolism of Arachidonic Acid22230337
D001095Arachidonic AcidsCYP1A2 protein results in increased chemical synthesis of Arachidonic Acids metabolite12675279
C059427aranidipinearanidipine results in decreased activity of CYP1A2 protein10805063
D001115ArecolineArecoline analog results in increased activity of CYP1A2 protein25056785
C000228aristolochic acid ICYP1A2 protein results in increased chemical synthesis of aristolochic acid I metabolite22086975
C000228aristolochic acid ICYP1A2 protein results in increased metabolism of aristolochic acid I26845733
C000228aristolochic acid ICYP1A2 protein results in increased oxidation of aristolochic acid I22086975
C000228aristolochic acid I[CYP1A2 protein results in increased oxidation of aristolochic acid I] which results in increased chemical synthesis of aristolochic acid I metabolite22086975
C000228aristolochic acid ICYP1A2 protein results in increased reduction of and results in increased activity of aristolochic acid I22086975
C000228aristolochic acid IOxygen deficiency affects the reaction [CYP1A2 protein results in increased metabolism of aristolochic acid I]26845733
C000228aristolochic acid I[[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] co-treated with [alpha-naphthoflavone results in decreased activity of CYP1A1 protein]] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C000228aristolochic acid I[CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]]21932800
C000228aristolochic acid ICYP1A2 protein promotes the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C000228aristolochic acid I[CYP1A2 protein results in increased oxidation of aristolochic acid I] which results in increased abundance of aristolochic acid I metabolite21932800
C000228aristolochic acid ICYP1A2 protein results in increased reduction of and results in increased oxidation of and affects the activity of aristolochic acid I21932800
C000228aristolochic acid I[furafylline results in decreased activity of CYP1A2 protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C000228aristolochic acid I[1-phenylazo-2-naphthol co-treated with aristolochic acid I] results in increased expression of CYP1A2 mRNA26845733
C000228aristolochic acid I[aristolochic acid I co-treated with 1-phenylazo-2-naphthol] results in increased expression of and results in increased activity of CYP1A2 protein26845733
C000228aristolochic acid Iaristolochic acid I results in increased expression of CYP1A2 mRNA26845733
C000228aristolochic acid ICYP1A2 protein results in increased abundance of aristolochic acid I metabolite21362632
C000228aristolochic acid ICYP1A2 protein results in increased metabolism of aristolochic acid I21362632|2684573
C000228aristolochic acid IOxygen deficiency affects the reaction [CYP1A2 protein results in increased metabolism of aristolochic acid I]26845733
C026987aroclor 1260aroclor 1260 results in increased expression of CYP1A2 mRNA24998970
D001140AroclorsAroclors results in increased expression of CYP1A2 protein29162470
C015001arsenitearsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]22159698
C015001arsenitearsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]22159698
C015001arseniteHemin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]22159698
C015001arsenitetin mesoporphyrin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]22159698
C075875artemisinartemisin results in decreased activity of CYP1A2 protein16261361
C031327artemisinineartemisinine results in decreased activity of CYP1A2 protein11124226
C031327artemisinineartemisinine results in increased expression of CYP1A2 mRNA17962186
C031327artemisinineartemisinine results in increased expression of CYP1A2 mRNA16919048
D001205Ascorbic AcidAscorbic Acid deficiency results in increased expression of CYP1A2 mRNA8269614
D001205Ascorbic AcidAscorbic Acid deficiency results in increased expression of CYP1A2 protein8269614
D001218AspartameAspartame results in increased activity of CYP1A2 protein16937917
C050701atipamezoleatipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]]16510159
C050701atipamezoleatipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]16510159
C050701atipamezoleatipamezole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
C050701atipamezoleatipamezole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16510159
D053626AtovaquoneAtovaquone results in increased activity of CYP1A2 protein11124226
D001280AtrazineAtrazine results in increased activity of CYP1A2 protein22310298
D001280AtrazineAtrazine results in increased expression of CYP1A2 mRNA22310298
D001280AtrazineAtrazine results in increased expression of CYP1A2 mRNA26775023
D001280Atrazinelycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]26775023
D001280AtrazineAtrazine results in increased activity of CYP1A2 protein9711812
C423185avasimibeavasimibe results in decreased activity of CYP1A2 protein15333513
D001374AzacitidineAzacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]12927368
D001374AzacitidineAzacitidine results in increased expression of CYP1A2 mRNA12927368
D001397AzoxymethaneAzoxymethane results in decreased expression of CYP1A2 mRNA18038451
C087670azoxystrobinazoxystrobin results in increased expression of CYP1A2 mRNA21784029
C087670azoxystrobinazoxystrobin results in increased expression of CYP1A2 protein21784029
C006680baicaleinbaicalein results in decreased activity of CYP1A2 protein21053930
C006680baicaleinCYP1A2 protein results in increased chemical synthesis of baicalein19666078
C006680baicalein[CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein19666078
C038044baicalin"3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]"26204831
C038044baicalin"3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]"26204831
C038044baicalinbaicalin results in increased expression of CYP1A2 mRNA26204831
C038044baicalinbaicalin results in increased expression of CYP1A2 protein26204831
C038044baicalinbaicalin results in increased expression of CYP1A2 mRNA26204831
C038044baicalinbaicalin results in increased expression of CYP1A2 protein26204831
C038044baicalinresveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]26204831
C038044baicalinresveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]26204831
C012765bakuchiolCYP1A2 protein results in increased metabolism of bakuchiol26712081
C061004benidipinebenidipine results in increased expression of CYP1A2 mRNA27732883
C011677benoxaprofenbenoxaprofen results in increased expression of CYP1A2 protein2069584
C030935benz(a)anthracenebenz(a)anthracene results in decreased activity of CYP1A2 protein11162773
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of CYP1A2 mRNA17253728|9783729
C030935benz(a)anthracene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benz(a)anthracene8961944
C030935benz(a)anthraceneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene]8961944
C030935benz(a)anthracene[andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1A2 mRNA17825862
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of CYP1A2 mRNA17825862
C030935benz(a)anthracene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benz(a)anthracene8961944
C030935benz(a)anthraceneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene]8961944
C030935benz(a)anthracene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of CYP1A2 mRNA21384493|2335814
C030935benz(a)anthraceneCYP1A2 protein affects the susceptibility to benz(a)anthracene21384493
D001551Benz(a)AnthracenesBenz(a)Anthracenes results in increased expression of CYP1A2 mRNA12107646
D001554BenzeneBenzene results in decreased expression of CYP1A29010585
D001554BenzeneBenzene results in decreased expression of CYP1A2 protein8517779
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA17690111
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased activity of CYP1A2 protein11162773
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CYP1A2 mRNA16269432|1725372
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of CYP1A2 mRNA12117779
C006703benzo(b)fluoranthene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
C006703benzo(b)fluoranthene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA18711122
C041512benzo(b)fluorenebenzo(b)fluorene results in increased expression of CYP1A2 mRNA17253728
C002615benzo(c)phenanthrene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene8961944
C002615benzo(c)phenanthreneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene]8961944
C002615benzo(c)phenanthrene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene8961944
C002615benzo(c)phenanthreneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene]8961944
D019324beta-Naphthoflavonebeta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D019324beta-Naphthoflavonebeta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]10936227
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased activity of CYP1A2 protein21053930
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased activity of CYP1A2 protein10923861|1472232
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 mRNA12623754|1472232
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 protein12584154|1562918
D019324beta-NaphthoflavoneCYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]]29180065
D019324beta-NaphthoflavoneCYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]29180065
D019324beta-NaphthoflavoneCYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]]29180065
D019324beta-NaphthoflavoneCYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]]29180065
D019324beta-NaphthoflavoneCYP1A2 gene mutant form promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]29180065
D019324beta-NaphthoflavoneCYP1A2 gene mutant form results in increased susceptibility to beta-Naphthoflavone29180065
D019324beta-Naphthoflavone[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA19737545
D019324beta-NaphthoflavoneBerberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]22342832
D019324beta-Naphthoflavonebeta-Naphthoflavone promotes the reaction [Oxygen results in increased activity of CYP1A2 protein]21745492
D019324beta-Naphthoflavonebeta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A2 mRNA]21745492
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased activity of CYP1A2 protein21745492
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 mRNA19737545|2174549
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 protein2208584|28201809
D019324beta-Naphthoflavone[beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]28201809
D019324beta-Naphthoflavone[beta-Naphthoflavone results in increased expression of CYP1A2 protein] which results in decreased susceptibility to Oxygen28201809
D019324beta-NaphthoflavoneCTNNB1 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]25174530
D019324beta-Naphthoflavone[furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [beta-Naphthoflavone results in increased activity of AHR protein]22491429
D019324beta-NaphthoflavoneOxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]29180065
D019324beta-NaphthoflavoneOxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]21745492
D019324beta-NaphthoflavonePregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]28428138
D019324beta-Naphthoflavonebeta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]10936227
D019324beta-Naphthoflavone"[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 protein"20448087
D019324beta-Naphthoflavonebeta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased activity of CYP1A2 protein10463385|1546616
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A2 protein26827781
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 mRNA10463385|1546616
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 protein10463385|1904129
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA18164116|2004503
D019324beta-Naphthoflavonediphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A2 protein]26880746
D019324beta-Naphthoflavonelead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]8902619
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A2 mRNA19464568
D019324beta-Naphthoflavonebeta-Naphthoflavone results in decreased activity of CYP1A2 protein19563207
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of CYP1A215507517|3377821
C105430benzofuranbenzofuran analog results in decreased activity of CYP1A2 protein15916432
D001572BenzofuransBenzofurans analog results in decreased activity of CYP1A2 protein15659567
D001572BenzofuransBenzofurans analog results in decreased activity of CYP1A2 protein15659567
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in decreased activity of CYP1A2 protein11162773
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of CYP1A2 mRNA11162773|1725372
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of CYP1A2 protein11162773|1137066
C022921benzo(k)fluoranthenesodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 mRNA]11162773
C022921benzo(k)fluoranthenesodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 protein]11162773
C022921benzo(k)fluoranthene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
D001564Benzo(a)pyrene"15,16-dihydrotanshinone I promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]"21262253
D001564Benzo(a)pyrene"15,16-dihydrotanshinone I promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]"21262253
D001564Benzo(a)pyrene2-oxohexyl isothiocyanate inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]19202560
D001564Benzo(a)pyrenealyssin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]19202560
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CYP1A2 mRNA"17690111
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA17690111
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA"17690111
D001564Benzo(a)pyreneBenzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased activity of CYP1A2 protein11162773
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of CYP1A2 protein19202560
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CYP1A2 mRNA10496959|1210764
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CYP1A2 protein11849738|1697093
D001564Benzo(a)pyrenebeta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16970932
D001564Benzo(a)pyrenebeta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16970932
D001564Benzo(a)pyrenechrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]20553787
D001564Benzo(a)pyrenecryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21262253
D001564Benzo(a)pyrenecryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]21262253
D001564Benzo(a)pyreneCYP1A2 protein affects the metabolism of Benzo(a)pyrene20542099
D001564Benzo(a)pyrene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of Benzo(a)pyrene8961944
D001564Benzo(a)pyreneCYP1A2 protein results in increased hydrolysis of Benzo(a)pyrene19919601
D001564Benzo(a)pyreneCYP1A2 protein results in increased metabolism of Benzo(a)pyrene2791199
D001564Benzo(a)pyrene[CYP1A2 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene27913846
D001564Benzo(a)pyreneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Benzo(a)pyrene]8961944
D001564Benzo(a)pyrenekaempferol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21256954
D001564Benzo(a)pyreneMelatonin inhibits the reaction [CYP1A2 protein results in increased hydrolysis of Benzo(a)pyrene]19919601
D001564Benzo(a)pyreneQuercetin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21256954
D001564Benzo(a)pyreneQuercetin inhibits the reaction [beta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]16970932
D001564Benzo(a)pyreneQuercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]16970932
D001564Benzo(a)pyreneresveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]10496959
D001564Benzo(a)pyrenesulforafan inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]19202560
D001564Benzo(a)pyrenetanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21262253
D001564Benzo(a)pyrenetanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]21262253
D001564Benzo(a)pyreneAHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of CYP1A2 mRNA]15034205
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with sodium bichromate] results in decreased expression of CYP1A2 mRNA22613061
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CYP1A2 mRNA15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of CYP1A2 protein15863256|1832186
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CYP1A2 mRNA11171528|1135690
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CYP1A2 protein17997381|1832186
D001564Benzo(a)pyreneBucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]1849469
D001564Benzo(a)pyreneColforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]1849469
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]18321868
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]18321868
D001564Benzo(a)pyreneCurcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]18321868
D001564Benzo(a)pyreneCycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]1849469
D001564Benzo(a)pyreneCYP1A2 protein affects the metabolism of Benzo(a)pyrene16256281
D001564Benzo(a)pyrene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of Benzo(a)pyrene8961944
D001564Benzo(a)pyreneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Benzo(a)pyrene]8961944
D001564Benzo(a)pyrene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
D001564Benzo(a)pyreneLipopolysaccharides inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]22466549
D001564Benzo(a)pyreneatipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]]16510159
D001564Benzo(a)pyreneatipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]16510159
D001564Benzo(a)pyreneatipamezole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D001564Benzo(a)pyreneatipamezole promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16510159
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of CYP1A2 mRNA"18711122
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of CYP1A2 mRNA18711122
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA"18711122
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of CYP1A2 mRNA18711122
D001564Benzo(a)pyreneBenzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of CYP1A2 mRNA21505853
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased activity of CYP1A2 protein21505853
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein16510159|2278525
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CYP1A2 mRNA16510159|1797389
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CYP1A2 protein8902619
D001564Benzo(a)pyreneDexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D001564Benzo(a)pyreneDexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D001564Benzo(a)pyreneGuanethidine inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]16510159
D001564Benzo(a)pyreneINS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]26466350
D001564Benzo(a)pyrenelead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]8902619
D001564Benzo(a)pyreneOxygen inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]24657529
D001564Benzo(a)pyrenePhenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D001564Benzo(a)pyrenePhenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16510159
D001564Benzo(a)pyrenePrazosin inhibits the reaction [Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]16510159
D001564Benzo(a)pyrenePrazosin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D001564Benzo(a)pyrenePrazosin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16510159
D001564Benzo(a)pyreneReserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D001564Benzo(a)pyreneReserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D001564Benzo(a)pyrene[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D001564Benzo(a)pyrene[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D001564Benzo(a)pyreneSulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]26466350
D001564Benzo(a)pyrenewortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]26466350
C006710benzotriphenylenebenzotriphenylene results in increased expression of CYP1A2 mRNA17253728
C017057benzoxazolonebenzoxazolone results in decreased activity of CYP1A2 protein15916432
C025383benzylideneacetoneCYP1A2 protein results in increased oxidation of benzylideneacetone15863696
C031403benzyl isothiocyanatebenzyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]22664424
C031403benzyl isothiocyanatebenzyl isothiocyanate results in increased expression of CYP1A2 mRNA22664424
C057754benzyloxyresorufinCYP1A2 protein results in decreased alkylation of benzyloxyresorufin11911841
C054108benzyl selenocyanatebenzyl selenocyanate binds to and results in decreased activity of CYP1A2 protein21732699
C054108benzyl selenocyanatebenzyl selenocyanate binds to CYP1A2 protein21732699
C054108benzyl selenocyanatebenzyl selenocyanate binds to CYP1A2 protein21732699
D001599BerberineBerberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]22342832
C068337bergamottinbergamottin results in increased expression of CYP1A2 protein18692084
C110652beta-apo-8'-carotenalbeta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16970932
C110652beta-apo-8'-carotenalbeta-apo-8'-carotenal results in increased expression of CYP1A2 protein16970932
C110652beta-apo-8'-carotenalQuercetin inhibits the reaction [beta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]16970932
C110652beta-apo-8'-carotenalQuercetin inhibits the reaction [beta-apo-8'-carotenal results in increased expression of CYP1A2 protein]16970932
C110652beta-apo-8'-carotenalbeta-apo-8'-carotenal results in increased expression of CYP1A2 mRNA9271336
C110652beta-apo-8'-carotenalbeta-apo-8'-carotenal results in increased expression of CYP1A2 mRNA9271336
D019207beta Carotenebeta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16970932
D019207beta CaroteneQuercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]16970932
D004958EstradiolCarbaryl inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D004958EstradiolChlorpyrifos inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D004958EstradiolCYP1A2 protein results in increased hydroxylation of Estradiol15961252
D004958EstradiolCYP1A2 protein results in increased metabolism of Estradiol16790556
D004958Estradiol[Estradiol binds to ESR2 protein] which results in increased expression of CYP1A2 mRNA20404318
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A2 mRNA19619570
D004958EstradiolEstradiol results in decreased expression of CYP1A2 mRNA28357125
D004958EstradiolEstradiol results in increased expression of CYP1A2 mRNA19619570
D004958EstradiolFonofos inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D004958Estradiolnaphthalene inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D004958EstradiolCYP1A2 protein results in increased hydroxylation of Estradiol10910964
C095105bexarotenebexarotene results in decreased expression of CYP1A2 mRNA16648578
C053541bicalutamide[bicalutamide binds to and results in decreased activity of AR protein] inhibits the reaction [Dehydroepiandrosterone results in decreased expression of CYP1A2 mRNA]23603339
C053541bicalutamidebicalutamide inhibits the reaction [Dehydroepiandrosterone results in increased degradation of CYP1A2 mRNA]23603339
D001663BilirubinBilirubin results in decreased activity of CYP1A2 protein16183037
C073710bilobalidebilobalide results in increased expression of and results in increased activity of CYP1A2 protein18421621
C073710bilobalidebilobalide results in increased expression of CYP1A2 mRNA18421621
C004541biochanin Abiochanin A results in decreased activity of CYP1A2 protein26278343
C004541biochanin ACYP1A2 protein results in increased metabolism of biochanin A12814970
C004541biochanin Abiochanin A results in decreased activity of CYP1A2 protein26278343
C006780bisphenol ACYP1A2 protein results in increased glutathionylation of bisphenol A23470418
C006780bisphenol ACYP1A2 protein results in increased glutathionylation of bisphenol A metabolite23470418
C006780bisphenol ACYP1A2 protein results in increased hydroxylation of bisphenol A23470418
C006780bisphenol ACYP1A2 protein results in increased hydroxylation of bisphenol A metabolite23470418
C006780bisphenol A"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP1A2 mRNA"28433925
C006780bisphenol Abisphenol A results in decreased expression of CYP1A2 mRNA25181051
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of CYP1A2 mRNA21784029
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of CYP1A2 protein21784029
D001786Blood GlucoseHemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein]26747958
D001786Blood GlucoseHemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of CYP1A2 protein]26747958
D001786Blood Glucose[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in decreased expression of CYP1A2 protein26747958
D001786Blood Glucose[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP1A2 protein26747958
D001786Blood Glucose[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein26747958
D001786Blood Glucose[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of CYP1A2 protein26747958
C584056BMS-764459BMS-764459 results in increased expression of CYP1A2 mRNA23831372
D000069286BortezomibCYP1A2 protein affects the metabolism of Bortezomib15764713
C032036bromobenzenebromobenzene results in decreased expression of CYP1A2 protein10547960
C025191bromodichloromethaneCYP1A2 protein results in increased metabolism of bromodichloromethane12076521
C025191bromodichloromethanebromodichloromethane results in decreased expression of CYP1A2 protein11295256
C025191bromodichloromethanebromodichloromethane results in increased expression of CYP1A2 protein11295256
C025191bromodichloromethaneCYP1A2 protein affects the metabolism of bromodichloromethane12062927
C025191bromodichloromethaneCYP1A2 protein results in increased metabolism of bromodichloromethane11295256|1207652
C025191bromodichloromethaneisosafrole inhibits the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane]12062927
C025191bromodichloromethaneTetrachlorodibenzodioxin promotes the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane]12062927
C083806brucine[brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein21800547
C010831bufuralolCYP1A2 protein results in increased hydroxylation of bufuralol9429232
D002083Butylated HydroxyanisoleButylated Hydroxyanisole results in increased expression of CYP1A2 mRNA25174530
D002083Butylated HydroxyanisoleCTNNB1 gene mutant form inhibits the reaction [Butylated Hydroxyanisole results in increased expression of CYP1A2 mRNA]25174530
D002084Butylated HydroxytolueneButylated Hydroxytoluene results in decreased activity of CYP1A2 protein18177683
C027561butylbenzyl phthalatebutylbenzyl phthalate results in decreased activity of CYP1A2 protein27432241
C474480butylcyclohexanebutylcyclohexane results in decreased activity of CYP1A2 protein15916432
C038091butylparabenbutylparaben results in decreased activity of CYP1A2 protein27432241
D002087ButyratesButyrates results in increased expression of CYP1A2 mRNA15252868
D002087ButyratesTetrachlorodibenzodioxin inhibits the reaction [Butyrates results in increased expression of CYP1A2 mRNA]15252868
D002101Cacodylic AcidCacodylic Acid results in increased expression of CYP1A2 mRNA17481689
D019256Cadmium ChlorideCadmium Chloride results in decreased activity of CYP1A2 protein11162773
C055494caffeic acid phenethyl estercaffeic acid phenethyl ester results in decreased expression of CYP1A2 protein22291063
C055494caffeic acid phenethyl ester[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA20360939
D002110CaffeineCaffeine results in decreased activity of CYP1A2 protein11465391|2421153
D002110CaffeineCiprofloxacin inhibits the reaction [CYP1A2 protein results in decreased methylation of Caffeine]11145498
D002110CaffeineCYP1A2 protein affects the metabolism of Caffeine1302044|14586384
D002110CaffeineCYP1A2 protein affects the metabolism of Caffeine metabolite1302044
D002110CaffeineCYP1A2 protein binds to and affects the metabolism of Caffeine15659567|1585640
D002110CaffeineCYP1A2 protein binds to Caffeine9334905
D002110CaffeineCYP1A2 protein results in decreased methylation of Caffeine11145498|1243379
D002110CaffeineCYP1A2 protein results in increased metabolism of Caffeine11907490|1921523
D002110Caffeine"[CYP1A2 protein results in increased metabolism of Caffeine] which results in increased chemical synthesis of 1,7-dimethylxanthine"19215233
D002110CaffeineGH1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Caffeine]11907490
D002110Caffeineresveratrol promotes the reaction [CYP1A2 protein results in increased metabolism of Caffeine]20716633
D002110Caffeinerofecoxib inhibits the reaction [CYP1A2 protein results in increased metabolism of Caffeine]16934051
D002110Caffeine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA28843594
D002110CaffeineCaffeine results in decreased activity of CYP1A2 protein18420780
D002110CaffeineCYP1A2 protein results in decreased methylation of Caffeine11376689
D002110Caffeine"Caffeine promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"12706856
D002110CaffeineCaffeine results in increased activity of CYP1A2 protein15822860
D002110CaffeineCYP1A2 protein affects the metabolism of Caffeine15619608
D002110CaffeineCYP1A2 protein binds to and affects the metabolism of Caffeine15659567
D002110Caffeine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Caffeine26599973
D002110Caffeine"[N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Caffeine"26599973
D002110CaffeineCYP1A2 protein results in decreased methylation of Caffeine20532872
C004645canadinecanadine results in increased expression of CYP1A2 mRNA28257954
C004645canadinecanadine results in increased expression of CYP1A2 protein28257954
D002185CannabidiolCannabidiol results in decreased activity of CYP1A2 protein24667653
D016644CanthaxanthinCanthaxanthin results in increased expression of CYP1A2 mRNA9271336
D016644CanthaxanthinCanthaxanthin results in increased expression of CYP1A2 mRNA9271336
D002211CapsaicinCapsaicin results in decreased activity of CYP1A2 protein22375877
D002220CarbamazepineCarbamazepine results in increased expression of CYP1A2 mRNA17112801
D002220Carbamazepine[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Carbamazepine23397584
D002220CarbamazepineCarbamazepine results in decreased expression of CYP1A2 mRNA17381134
D002220CarbamazepineCYP1A2 protein results in increased metabolism of Carbamazepine10907977
D012721CarbarylCarbaryl inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
D012721CarbarylCarbaryl inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D012721CarbarylCarbaryl results in decreased activity of CYP1A2 protein16790556
D012721CarbarylCarbaryl results in increased expression of CYP1A2 protein9858662
C006698carbendazimcarbendazim results in increased expression of CYP1A2 mRNA21784029
C006698carbendazimcarbendazim results in increased expression of CYP1A2 protein21784029
D002235CarbofuranCYP1A2 protein results in increased hydroxylation of Carbofuran15560889
D002251Carbon TetrachlorideADAM8 protein affects the reaction [Carbon Tetrachloride results in increased expression of CYP1A2 mRNA]24646716
D002251Carbon TetrachlorideADAM8 protein affects the reaction [Carbon Tetrachloride results in increased expression of CYP1A2 protein]24646716
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CYP1A2 mRNA17084009|1803845
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CYP1A2 protein16445600
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CYP1A2 mRNA24646716
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of CYP1A2 protein24646716
D002251Carbon TetrachlorideCYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP1A2 mRNA]17084009
D002251Carbon Tetrachloride"[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with Carbon Tetrachloride] results in increased expression of CYP1A2 mRNA"20930465
D002251Carbon Tetrachloride"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline promotes the reaction [Carbon Tetrachloride results in decreased expression of CYP1A2 protein]"20930465
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of CYP1A2 mRNA15963342
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased activity of CYP1A2 protein14706259|1628878
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CYP1A2 mRNA14706259|1623916
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CYP1A2 protein17606319|2093046
D002251Carbon TetrachlorideCurcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A2 protein]16288784
D002251Carbon TetrachlorideCYP1A2 protein results in increased metabolism of Carbon Tetrachloride15988118
D002338CarotenoidsCYP1A2 protein polymorphism affects the susceptibility to Carotenoids15095308
C024714caryophyllenecaryophyllene results in decreased activity of CYP1A2 protein29074051
C024714caryophyllenecaryophyllene results in decreased activity of CYP1A2 protein29074051
C515179caryophyllene oxidecaryophyllene oxide results in decreased activity of CYP1A2 protein29074051
C515179caryophyllene oxidecaryophyllene oxide results in decreased activity of CYP1A2 protein29074051
D002395Catecholamines[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D002395Catecholamines[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D000068579CelecoxibCelecoxib results in decreased activity of CYP1A2 protein18816299
C088453Celsior[Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A2 mRNA15448115
C088453CelsiorCelsior results in decreased activity of CYP1A2 protein15448115
C088453CelsiorCelsior results in decreased expression of CYP1A2 mRNA15448115
D002599ChalconeCYP1A2 protein results in increased hydroxylation of Chalcone15863696
D002635Chenodeoxycholic AcidChenodeoxycholic Acid results in decreased expression of CYP1A2 mRNA27174168
C473711Chir 99021Chir 99021 results in increased expression of CYP1A2 mRNA26259606
D002719ChlormethiazoleChlormethiazole results in decreased expression of CYP1A2 mRNA10751552
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA16049271|1693415
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 protein17851650
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA16049271
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA25270620
D020111Chlorodiphenyl (54% Chlorine)CYP1A2 affects the susceptibility to Chlorodiphenyl (54% Chlorine)19772856
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased activity of CYP1A2 protein11713002|8471063
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 mRNA11163329|1604927
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1A2 protein8471063
C543063chloroxoquinolinechloroxoquinoline results in increased expression of CYP1A2 mRNA26397835
D002746Chlorpromazine[Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA27344345
D002746ChlorpromazineChlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D002746Chlorpromazine[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine23397584
D002746ChlorpromazineCYP1A2 protein results in decreased methylation of Chlorpromazine20615392
D002746ChlorpromazineCYP1A2 protein results in decreased susceptibility to Chlorpromazine26477383
D002746ChlorpromazineCYP1A2 protein results in increased metabolism of and results in increased activity of Chlorpromazine19482014
D002746ChlorpromazineCYP1A2 protein results in increased oxidation of Chlorpromazine20615392
D002746ChlorpromazineChlorpromazine affects the expression of CYP1A2 mRNA18246545
D002746ChlorpromazineChlorpromazine results in increased expression of CYP1A2 mRNA25596134
D004390ChlorpyrifosChlorpyrifos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
D004390ChlorpyrifosChlorpyrifos inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D004390ChlorpyrifosChlorpyrifos results in decreased activity of CYP1A2 protein16790556|2018306
D004390ChlorpyrifosChlorpyrifos results in decreased expression of CYP1A2 protein21784029
D004390ChlorpyrifosChlorpyrifos results in increased expression of CYP1A2 mRNA16190164|1932676
D004390ChlorpyrifosCYP1A2 protein affects the metabolism of Chlorpyrifos15557345|1707935
C007033chlortoluronCYP1A2 protein results in decreased susceptibility to chlortoluron24920432
D002753ChlorzoxazoneCYP1A2 protein affects the metabolism of Chlorzoxazone14586387
D002753ChlorzoxazoneCYP1A2 protein affects the metabolism of Chlorzoxazone15879494
D002753ChlorzoxazoneCYP1A2 protein results in increased hydroxylation of Chlorzoxazone11911841
D002793Cholic Acids[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA27344345
D002793Cholic Acids[Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA27344345
D002794Choline"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP1A2 mRNA"28973532
D002794Choline[LEP gene mutant form results in increased susceptibility to [Methionine co-treated with Choline]] which results in decreased expression of CYP1A2 mRNA27712037
D002794Choline[LEP gene mutant form results in increased susceptibility to [Methionine co-treated with Choline]] which results in decreased expression of CYP1A2 protein27712037
D002794Choline"[Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA"28163111
D002794CholineCholine deficiency inhibits the reaction [Acetaminophen results in increased expression of CYP1A2 protein]18798224
D002794CholineCholine deficiency promotes the reaction [Phenobarbital results in increased expression of CYP1A2 protein]18798224
C031180chrysenechrysene results in increased expression of CYP1A2 mRNA12107646|1725372
C031180chrysene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of chrysene8961944
C031180chryseneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene]8961944
C031180chrysene[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of chrysene8961944
C031180chryseneEPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene]8961944
C031180chrysene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
C043561chrysinchrysin results in decreased activity of CYP1A2 protein20806393|2105393
C043561chrysinCYP1A2 protein results in increased metabolism of chrysin19666078
C043561chrysin[CYP1A2 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein19666078
C007054chrysoeriolchrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]20553787
C027113chrysophanic acidchrysophanic acid results in decreased activity of CYP1A2 protein27633141
C039671ciglitazone[ciglitazone binds to PPARG protein alternative form] which results in increased expression of CYP1A2 mRNA16197558
C039671ciglitazone[ciglitazone binds to PPARG protein] which results in increased expression of CYP1A2 mRNA16197558
D002927CimetidineCimetidine results in decreased activity of CYP1A2 protein19909766
D002927Cimetidinestyrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP1A2 protein]19909766
C019304ciprofibrateciprofibrate inhibits the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]17962186
C019304ciprofibrateciprofibrate results in decreased expression of CYP1A2 mRNA17962186
C019304ciprofibrateciprofibrate results in decreased expression of CYP1A2 mRNA7676460
D002939CiprofloxacinCiprofloxacin inhibits the reaction [CYP1A2 protein affects the metabolism of tizanidine]15592331
D002939CiprofloxacinCiprofloxacin inhibits the reaction [CYP1A2 protein results in decreased methylation of Caffeine]11145498
D002939CiprofloxacinCiprofloxacin results in decreased activity of CYP1A2 protein11145498|1559233
D002939Ciprofloxacin[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine11151749
D002939Ciprofloxacin[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of norclozapine11151749
D002939CiprofloxacinCiprofloxacin results in decreased activity of CYP1A2 protein16556082
D002939Ciprofloxacin[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Theophylline16556082
D017291Clarithromycin[Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]11408986
D002976ClenbuterolClenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15710352
D002976ClenbuterolPropranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]15710352
D004002Clodronic AcidClodronic Acid results in increased expression of CYP1A2 mRNA25596134
D002994ClofibrateClofibrate results in decreased expression of CYP1A2 mRNA19952500
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of CYP1A2 mRNA17585979
D002994ClofibrateClofibrate results in decreased expression of CYP1A2 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP1A2 mRNA]17585979
D002994ClofibrateClofibrate results in decreased expression of CYP1A2 mRNA11328961|1285110
D002994ClofibrateClofibrate results in decreased expression of CYP1A2 protein17967931|1867016
D002995Clofibric AcidClofibric Acid affects the expression of CYP1A2 mRNA17602206
C005055cloflucarbancloflucarban results in increased expression of CYP1A2 mRNA21784029
C005055cloflucarbancloflucarban results in increased expression of CYP1A2 protein21784029
C055162clopidogrelCYP1A2 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite19170597
C055162clopidogrelCYP1A2 protein results in increased oxidation of clopidogrel19812348
C055162clopidogrelfurafylline inhibits the reaction [CYP1A2 protein results in increased oxidation of clopidogrel]19812348
D003022ClotrimazoleClotrimazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]19858067
D003022ClotrimazoleClotrimazole results in increased expression of CYP1A2 protein7986207
D003024Clozapine[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine11151749
D003024ClozapineClozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D003024ClozapineCYP1A2 gene polymorphism affects the metabolism of Clozapine16044115
D003024ClozapineCYP1A2 gene SNP affects the susceptibility to Clozapine15206669
D003024ClozapineCYP1A2 gene SNP results in decreased metabolism of Clozapine12919186
D003024ClozapineCYP1A2 gene SNP results in decreased susceptibility to Clozapine11763009
D003024ClozapineCYP1A2 gene SNP results in increased metabolism of Clozapine11763009|1520666
D003024ClozapineCYP1A2 protein affects the metabolism of Clozapine15286053|1588314
D003024ClozapineCYP1A2 protein affects the susceptibility to Clozapine12919186
D003024Clozapine[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine23397584
D003024ClozapineCYP1A2 protein polymorphism affects the metabolism of Clozapine15949157
D003024ClozapineCYP1A2 protein results in increased metabolism of Clozapine16044115|1880973
D003024ClozapineSmoke affects the reaction [CYP1A2 gene polymorphism affects the metabolism of Clozapine]16044115
D003024ClozapineSmoke promotes the reaction [CYP1A2 protein results in increased metabolism of Clozapine]16044115
D003024ClozapineClozapine results in increased expression of CYP1A2 mRNA12969762
D003024ClozapineCYP1A2 protein results in increased metabolism of Clozapine12969762
D003024ClozapineClozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D003024ClozapineCYP1A2 protein affects the metabolism of Clozapine10519459|1083015
C079149clozapine N-oxideCYP1A2 protein results in increased abundance of clozapine N-oxide27320963
C079149clozapine N-oxideCYP1A2 protein results in increased chemical synthesis of clozapine N-oxide18809730
C079149clozapine N-oxideFluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of clozapine N-oxide]18809730
D003033Coal TarCoal Tar results in increased expression of CYP1A2 mRNA16882163
C018021cobaltous chloridecobaltous chloride results in decreased expression of CYP1A2 mRNA24386269
C004690coclaurine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA28843594
D009249NADP"[CYP1A2 protein co-treated with NADP co-treated with Glutathione] results in increased glutathionylation of and results in increased activity of 7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine"20825217
D009249NADPKetoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D009249NADP[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid24120545
D009249NADPNADP promotes the reaction [resveratrol results in decreased activity of CYP1A2 protein]11714871
D009249NADPQuercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D009249NADPThioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D009249NADPTranylcypromine affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D003069CoffeeCoffee results in increased expression of CYP1A2 mRNA18028974
D003069CoffeeNFE2L2 protein promotes the reaction [Coffee results in increased expression of CYP1A2 mRNA]18028974
D005576ColforsinColforsin affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]1849469
D005576ColforsinColforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15710352
D003276Contraceptives, Oral"Contraceptives, Oral results in decreased activity of CYP1A2 protein"17089110
D003300Copper[CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol15576237
D019327Copper SulfateCopper Sulfate results in decreased expression of CYP1A2 mRNA19549813
C007133cortisol succinate[cortisol succinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A218347083
D003367CotinineCotinine results in decreased activity of CYP1A2 protein15916432
D003367CotinineCotinine results in increased activity of CYP1A2 protein16203240
C043168coumarancoumaran results in decreased activity of CYP1A2 protein15916432
C030123coumarincoumarin affects the expression of CYP1A2 mRNA16963487
C030123coumarincoumarin results in decreased expression of CYP1A2 mRNA18480146
D003407CreosoteCreosote results in increased expression of CYP1A2 mRNA19389177
C037886cryptotanshinonecryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21262253
C037886cryptotanshinonecryptotanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]21262253
C037886cryptotanshinonecryptotanshinone results in increased expression of CYP1A2 mRNA21262253
C037886cryptotanshinonecryptotanshinone results in increased expression of CYP1A2 protein21262253
C037886cryptotanshinoneDactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA]21262253
C037886cryptotanshinoneresveratrol inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA]21262253
D003474CurcuminCurcumin results in decreased activity of CYP1A2 protein15841493
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]18321868
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]18321868
D003474CurcuminCurcumin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]18321868
D003474CurcuminCurcumin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP1A2 protein]16288784
C057862cyanoginosin LRcyanoginosin LR results in increased expression of CYP1A2 mRNA17383702
C084639cyclobarbitalcyclobarbital results in increased expression of CYP1A2 mRNA10064569
D003505CyclodextrinsCyclodextrins analog results in decreased activity of CYP1A2 protein15665498
D003513CycloheximideCycloheximide affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]1849469
D003520CyclophosphamideCyclophosphamide results in decreased activity of CYP1A2 protein18420780
D016572CyclosporineCyclosporine results in decreased expression of CYP1A2 mRNA25596134
C037304cyhalothrincyhalothrin results in increased activity of CYP1A2 protein22310298
C089595cylindrospermopsincylindrospermopsin results in increased expression of CYP1A2 mRNA21607682
C017160cypermethrincypermethrin results in decreased activity of CYP1A2 protein18420780
C017160cypermethrincypermethrin results in increased expression of CYP1A2 mRNA23447098
C093628cyproconazolecyproconazole results in increased expression of CYP1A2 mRNA22334560|2565664
C093628cyproconazoleNR1I3 promotes the reaction [cyproconazole results in increased expression of CYP1A2 mRNA]25656644
D0150842,4-Dichlorophenoxyacetic Acid"2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1A2 mRNA"10910964
D003606DacarbazineCYP1A2 protein results in increased metabolism of Dacarbazine metabolite11751525
D003606DacarbazineO(6)-benzylguanine inhibits the reaction [CYP1A2 protein results in increased metabolism of Dacarbazine metabolite]11751525
D003609Dactinomycin"Dactinomycin inhibits the reaction [15,16-dihydrotanshinone I results in increased expression of CYP1A2 mRNA]"21262253
D003609DactinomycinDactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA]21262253
D003609DactinomycinDactinomycin inhibits the reaction [tanshinone results in increased expression of CYP1A2 mRNA]21262253
C004742daidzeindaidzein results in decreased activity of CYP1A2 protein18420780
D003620DantroleneDantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D003630Daunorubicin[pyridoxal isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A2 protein15588138
D003630Daunorubicin[salicylaldehyde isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A2 protein15588138
C010902decabromobiphenyl etherdecabromobiphenyl ether analog results in increased expression of CYP1A2 mRNA26854739
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of CYP1A2 mRNA19270788
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased activity of CYP1A2 protein18495385
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of CYP1A2 mRNA18495385
C010902decabromobiphenyl etherdecabromobiphenyl ether results in increased expression of CYP1A2 protein20686340
C017180decamethrindecamethrin results in increased expression of CYP1A2 mRNA16494911|1685967
C017180decamethrindecamethrin results in increased expression of CYP1A2 protein16859670
C109757decan-4-olidedecan-4-olide results in decreased activity of CYP1A2 protein15916432
C014347decitabinedecitabine results in increased expression of CYP1A2 mRNA19274061|2835712
D003671DEETCYP1A2 protein results in increased metabolism of DEET11854147
D003671DEETDEET results in increased expression of CYP1A2 mRNA19326769|2709163
D003671DEET[fipronil co-treated with DEET] results in increased expression of CYP1A2 mRNA27091632
D003687Dehydroepiandrosterone[bicalutamide binds to and results in decreased activity of AR protein] inhibits the reaction [Dehydroepiandrosterone results in decreased expression of CYP1A2 mRNA]23603339
D003687Dehydroepiandrosteronebicalutamide inhibits the reaction [Dehydroepiandrosterone results in increased degradation of CYP1A2 mRNA]23603339
D003687DehydroepiandrosteroneDehydroepiandrosterone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]23603339
D003687DehydroepiandrosteroneDehydroepiandrosterone results in decreased expression of CYP1A2 mRNA23603339
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased degradation of CYP1A2 mRNA23603339
D003849DeoxyguanosineCYP1A2 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]21907773
D003849DeoxyguanosineCYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine]21907773
C047386desethylamodiaquinedesethylamodiaquine results in decreased activity of CYP1A2 protein11124226
D017135DesogestrelDesogestrel results in decreased activity of CYP1A2 protein18816299
D003907Dexamethasone[Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]19022236
D003907Dexamethasone[Dexamethasone co-treated with Mifepristone] results in increased activity of CYP1A2 protein19022236
D003907DexamethasoneDexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]19022236
D003907DexamethasoneDexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]19022236
D003907DexamethasoneDexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19022236
D003907DexamethasoneDexamethasone results in decreased activity of CYP1A2 protein19022236
D003907DexamethasoneDexamethasone results in decreased expression of CYP1A2 protein19022236
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]19022236
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]19022236
D003907DexamethasoneDexamethasone affects the expression of CYP1A2 mRNA15102944
D003907DexamethasoneDexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17690134
D003907DexamethasoneDexamethasone results in decreased expression of CYP1A2 mRNA11328961|2060781
D003907DexamethasoneDexamethasone results in increased expression of CYP1A2 mRNA15607757
D003907DexamethasoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]17690134
D020927Dexmedetomidineatipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]]16510159
D020927Dexmedetomidineatipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]16510159
D020927DexmedetomidineDexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D020927DexmedetomidineDexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D016264Dextran SulfateDextran Sulfate results in decreased activity of CYP1A2 protein28438436
D016264Dextran Sulfate[Dextran Sulfate results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of Acetaminophen28438436
C028009diallyl disulfidediallyl disulfide results in increased expression of CYP1A2 protein16000231
C042577diallyl trisulfidediallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein]28115069
D036381DiarylheptanoidsDiarylheptanoids results in decreased activity of CYP1A2 protein23850985
D003976DiazinonCYP1A2 protein affects the metabolism of Diazinon15557345|1576440
D003976DiazinonCYP1A2 protein results in decreased sulfation of and results in increased activity of Diazinon15764407
D003976DiazinonCYP1A2 protein results in increased metabolism of and results in increased activity of Diazinon11708902
D003976DiazinonDiazinon results in increased expression of CYP1A2 mRNA21784029
D003976DiazinonDiazinon results in increased expression of CYP1A2 protein21784029
D003976Diazinon[Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon17442507
C041517dibenzo(a,l)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA"17690111
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of CYP1A2 mRNA"16269432
C041517dibenzo(a,l)pyrene"CYP1A2 protein results in increased activity of dibenzo(a,l)pyrene"15606143
C041517dibenzo(a,l)pyrene"[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA"18711122
C041517dibenzo(a,l)pyrene"[Benzo(a)pyrene co-treated with dibenzo(a,l)pyrene] affects the expression of CYP1A2 mRNA"18711122
C018911dibenzoanthracene-1,2-dihydrodiol"[CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene] which results in increased chemical synthesis of dibenzoanthracene-1,2-dihydrodiol"8638931
C018912dibenzoanthracene-3,4-dihydrodiol"[CYP1A2 protein results in increased metabolism of 1,2,5,6-dibenzanthracene] which results in increased chemical synthesis of dibenzoanthracene-3,4-dihydrodiol"8638931
C023614dibenzofurandibenzofuran metabolite results in increased activity of CYP1A2 protein26032510
C023614dibenzofuran[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA7750161
C023614dibenzofurandibenzofuran results in increased activity of CYP1A2 protein8001243
D000072338Dibenzofurans, Polychlorinated"[Polychlorinated Biphenyls co-treated with Dibenzofurans, Polychlorinated] results in increased activity of CYP1A2 protein"17051818
D000072338Dibenzofurans, Polychlorinated"[Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1A2 mRNA"17850846
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased activity of CYP1A2 protein27432241
D003994BucladesineBucladesine affects the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]1849469
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of CYP1A2 mRNA28962523
D002945CisplatinCisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D002945CisplatinCisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004008Diclofenac[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Diclofenac23397584
D004008DiclofenacDiclofenac metabolite results in decreased activity of CYP1A2 protein28960974
D004008DiclofenacDiclofenac results in increased expression of CYP1A2 mRNA21784029
D004008DiclofenacDiclofenac results in increased expression of CYP1A2 protein21784029
C004354dicloranCYP1A2 protein results in decreased nitrosation of dicloran3137698
D004010DicofolDicofol results in increased expression of CYP1A2 mRNA19595748
C000944dicrotophosdicrotophos results in increased expression of CYP1A2 mRNA28302478
C121718dicyclanil[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA20118626
C121718dicyclanil[[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] which results in increased abundance of Reactive Oxygen Species20118626
C121718dicyclanildicyclanil results in increased expression of CYP1A2 mRNA15664270
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in decreased activity of CYP1A2 protein27432241
D004026DieldrinDieldrin results in increased expression of CYP1A2 mRNA10910964
D004041Dietary Fatsalpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]26102010
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 mRNA28433925
D004041Dietary Fats[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA26102010
D004041Dietary FatsDietary Fats results in decreased expression of CYP1A2 mRNA22609946|2501614
D004041Dietary FatsDietary Fats results in increased expression of CYP1A2 protein23358370
D004041Dietary Fatstetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]26102010
D004041Dietary Fats"1,7-phenanthroline inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein]"17967931
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 mRNA17967931
D004041Dietary Fats[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein17967931
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 mRNA28433925
D019422Dietary Sucrose"1,7-phenanthroline inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein]"17967931
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 mRNA17967931
D019422Dietary Sucrose[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of CYP1A2 protein17967931
D004051Diethylhexyl Phthalate"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP1A2 mRNA"28433925
D004052Diethylnitrosamine[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA20118626
D004052Diethylnitrosamine[[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] which results in increased abundance of Reactive Oxygen Species20118626
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of CYP1A2 mRNA24535843
D004052DiethylnitrosamineAcetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]22129741
D004052Diethylnitrosamineallyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP1A2 protein]23494807
D004052Diethylnitrosamineallyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP1A2 mRNA]23494807
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA18164116|2004503
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA20360939
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA20033131
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of CYP1A2 mRNA20033131
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A2 mRNA20033131
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP1A2 mRNA28943392
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of and results in decreased activity of CYP1A2 protein23494807|2756556
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of CYP1A2 mRNA19638242|2036093
D004052Diethylnitrosamine[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA18253720
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA22129741
D004052Diethylnitrosamine[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA22687989
D004052Diethylnitrosamine[oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA18754104
C007379diethyl phthalatediethyl phthalate results in decreased activity of CYP1A2 protein27432241
D004054DiethylstilbestrolCYP1A2 protein affects the susceptibility to Diethylstilbestrol8242868
D004075DiglyceridesDiglycerides results in increased stability of and results in increased activity of CYP1A2 protein15966743
C039060dihydroartemisinindihydroartemisinin results in decreased activity of CYP1A2 protein11124226
C012906dihydrocapsaicindihydrocapsaicin results in decreased activity of CYP1A2 protein22375877
D002396Catechols[CYP1A2 protein results in increased hydroxylation of zearalenol] which results in increased chemical synthesis of Catechols19931366
D002396Catechols[CYP1A2 protein results in increased hydroxylation of Zearalenone] which results in increased chemical synthesis of Catechols19931366
C066888dimethocaineCYP1A2 protein results in increased hydroxylation of dimethocaine24309420
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of CYP1A2 mRNA27638505
D0151279,10-Dimethyl-1,2-benzanthracene"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"19276279
D0151279,10-Dimethyl-1,2-benzanthracene"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein]"17183067
D0151279,10-Dimethyl-1,2-benzanthracene"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"17183067
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein"17183067
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA"17183067|1927627
D0151279,10-Dimethyl-1,2-benzanthracene"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"8961944
D0151279,10-Dimethyl-1,2-benzanthracene"EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"8961944
D0151279,10-Dimethyl-1,2-benzanthracene"isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"25110319
D0151279,10-Dimethyl-1,2-benzanthracene"S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"19276279
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein"22044346
D0151279,10-Dimethyl-1,2-benzanthracene"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein]"22044346
D0151279,10-Dimethyl-1,2-benzanthracene"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"8961944
D0151279,10-Dimethyl-1,2-benzanthracene"CYP1A2 protein results in increased activity of 9,10-Dimethyl-1,2-benzanthracene"15606143
D0151279,10-Dimethyl-1,2-benzanthracene"EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"8961944
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein"16054776
D004126DimethylformamideDimethylformamide results in decreased expression of CYP1A2 protein10547960
C073972dimethyl mercury[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]21424224
C073972dimethyl mercurydimethyl mercury results in decreased expression of CYP1A2 protein21424224
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of CYP1A2 mRNA17072980
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of CYP1A2 protein16997515
C024629dimethyl phthalatedimethyl phthalate results in decreased activity of CYP1A2 protein27432241
D004121Dimethyl Sulfoxide[cortisol succinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP1A218347083
D004121Dimethyl SulfoxideDimethyl Sulfoxide affects the expression of CYP1A2 mRNA12843640
D004130N,N-Dimethyltryptamine"CYP1A2 protein results in increased metabolism of N,N-Dimethyltryptamine"27320963
C106479di-n-propylphthalatedi-n-propylphthalate results in decreased activity of CYP1A2 protein27432241
C039602diosmetindiosmetin results in decreased activity of CYP1A2 protein28867436
D004147DioxinsDioxins results in increased expression of CYP1A2 mRNA15977188|2341963
D004147DioxinsDioxins results in increased expression of CYP1A2 protein15977188
C010574diphenylCYP1A2 protein results in increased oxidation of diphenyl27137136
C010574diphenyldiphenyl results in decreased activity of CYP1A2 protein15916432
C493087diphenylarsinic aciddiphenylarsinic acid results in decreased expression of CYP1A2 mRNA23999541
C007517diphenyleneiodoniumdiphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A2 protein]26880746
C007517diphenyleneiodoniumdiphenyleneiodonium results in decreased activity of CYP1A2 protein26880746
D004050DitiocarbDitiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004050DitiocarbDitiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004237DiuronDiuron results in increased expression of CYP1A2 mRNA21784029|2231029
D004237DiuronDiuron results in increased expression of CYP1A2 protein21784029
D0192972,4-Dinitrophenol"2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D0192972,4-Dinitrophenol"2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
C067311docetaxelCYP1A2 gene SNP affects the susceptibility to docetaxel23758476
D004281Docosahexaenoic AcidsDocosahexaenoic Acids results in decreased activity of CYP1A2 protein16978661
D004294DomperidoneCYP1A2 protein results in increased hydroxylation of Domperidone15327587
D007980LevodopaLevodopa inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004298DopamineDopamine results in decreased activity of CYP1A2 protein18420780
D004317DoxorubicinDoxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004317Doxorubicin[pyridoxal isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A2 protein15588138
D004317Doxorubicin[salicylaldehyde isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A2 protein15588138
D004317DoxorubicinDoxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of CYP1A2 mRNA"23262642
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"16901605
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in decreased expression of CYP1A2 mRNA"26590097
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased activity of CYP1A2 protein"24494561
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of CYP1A2 mRNA"16901605
D000068736Duloxetine HydrochlorideCYP1A2 protein results in increased activity of and results in increased glutathionylation of Duloxetine Hydrochloride20669986
D000068736Duloxetine Hydrochloride[furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride20669986
D004391DustDust results in increased expression of CYP1A2 mRNA21056094
D015118Eicosapentaenoic AcidEicosapentaenoic Acid results in decreased activity of CYP1A2 protein16978661
C034192ellipticineCYP1A2 protein results in increased metabolism of ellipticine22917556
C034192ellipticineellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C034192ellipticineellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D004642Emodin[CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite27989148
D004642EmodinCYP1A2 protein results in increased oxidation of Emodin27989148
D004642EmodinEmodin results in decreased activity of CYP1A2 protein27633141
D004642EmodinEmodin analog results in decreased activity of CYP1A2 protein22185593
D004642EmodinEmodin results in decreased activity of CYP1A2 protein22185593
C105196enfuvirtideenfuvirtide affects the activity of CYP1A2 protein15656696
D015365EnoxacinEnoxacin inhibits the reaction [CYP1A2 protein affects the metabolism of Fluvoxamine]15905806
D015365EnoxacinEnoxacin results in decreased activity of CYP1A2 protein15905806
D015365EnoxacinEnoxacin binds to CYP1A2 protein8905919
D015365EnoxacinEnoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]8905919
C045651epigallocatechin gallateepigallocatechin gallate binds to CYP1A2 protein23010222
C109476epoxiconazoleepoxiconazole results in increased expression of CYP1A2 mRNA22334560
C091891epsilon-viniferinepsilon-viniferin results in decreased activity of CYP1A2 protein12818727
C073539erucinerucin results in increased expression of CYP1A2 protein20833222
C007633estragoleCYP1A2 protein results in increased hydroxylation of estragole19920071
D004967EstrogensCYP1A2 protein results in increased hydroxylation of Estrogens15734958
D004970EstroneCYP1A2 protein binds to Estrone27966929
D004970EstroneCYP1A2 protein promotes the reaction [Estrone binds to Deoxyguanosine]21907773
D004977EthambutolEthambutol results in decreased activity of CYP1A2 protein24910189
D000431EthanolEthanol results in increased expression of CYP1A2 mRNA23273579
D000431EthanolEthanol results in increased expression of CYP1A2 protein26747958
D000431EthanolHemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein]26747958
D000431Ethanol[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in decreased expression of CYP1A2 protein26747958
D000431Ethanol[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP1A2 protein26747958
D000431Ethanol[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein26747958
D004997Ethinyl EstradiolCYP1A2 protein results in increased hydroxylation of Ethinyl Estradiol15304426
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein16198659
D004997Ethinyl Estradiol[[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein] which results in decreased metabolism of tizanidine16198659
D004997Ethinyl Estradiol[Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP1A2 protein16291717
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased activity of CYP1A2 protein18816299
D005015EthoxyquinEthoxyquin results in increased expression of CYP1A2 mRNA19695238
C024565ethylene dichlorideethylene dichloride results in decreased expression of CYP1A2 mRNA28189721
C039614ethylisopropylamilorideethylisopropylamiloride results in decreased activity of CYP1A2 protein15081870
C012313ethyl-p-hydroxybenzoateethyl-p-hydroxybenzoate results in decreased activity of CYP1A2 protein27432241
D017308EtodolacEtodolac results in decreased activity of CYP1A2 protein18816299
C422649etoricoxibetoricoxib results in decreased activity of CYP1A2 protein18816299
D005054Eugenol[CYP1A2 protein co-treated with Copper] results in increased activity of Eugenol15576237
D015025ZearalenoneCYP1A2 protein results in increased hydroxylation of Zearalenone19931366
D015025Zearalenone[CYP1A2 protein results in increased hydroxylation of Zearalenone] which results in increased chemical synthesis of Catechols19931366
D005204FarnesolFarnesol results in increased activity of CYP1A2 protein15840382
C047360felbamatefelbamate results in decreased expression of CYP1A2 mRNA17381134
D015736FelodipineFelodipine results in increased expression of CYP1A2 mRNA27732883
C033789fenarimol[fenarimol co-treated with acephate] affects the expression of CYP1A2 protein17686559
C033789fenarimol[fenarimol co-treated with vinclozolin] affects the expression of CYP1A2 protein17686559
C033789fenarimol[fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A2 protein17686559
D005273FenbendazoleFenbendazole results in decreased activity of CYP1A2 protein22048645
D005273FenbendazoleFenbendazole affects the expression of CYP1A2 mRNA26366864
D005278FenitrothionFenitrothion results in decreased activity of CYP1A2 protein20183062|2263405
D005278FenitrothionFenitrothion results in increased expression of CYP1A2 mRNA22310298
D011345FenofibrateFenofibrate affects the expression of CYP1A2 mRNA20801182|2559613
D011345Fenofibrate[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA18253720
C026013fenproporexCYP1A2 protein results in decreased alkylation of fenproporex15294457
C017690fenvaleratefenvalerate results in increased activity of CYP1A2 protein22310298
C004999ferulic acidferulic acid results in decreased activity of CYP1A2 protein15841493
D018120FinasterideFinasteride results in decreased expression of CYP1A2 mRNA24136188
C082360fipronil[fipronil co-treated with DEET] results in increased expression of CYP1A2 mRNA27091632
D005411Flame RetardantsFlame Retardants results in increased expression of CYP1A218774282
C028610flavanoneflavanone results in decreased activity of CYP1A2 protein21053930
C043562flavoneflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17090139
C043562flavoneflavone results in decreased activity of CYP1A2 protein21053930
C043562flavoneflavone results in decreased activity of CYP1A2 protein19563207
D005421Flavoring AgentsFlavoring Agents results in decreased activity of CYP1A2 protein15529323
D015725FluconazoleFluconazole results in increased expression of CYP1A2 mRNA16730040
C012976flumequine"[flumequine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA"23681119
C014558flunixin meglumineflunixin meglumine affects the expression of CYP1A2 mRNA26366864
C007738fluoranthenefluoranthene results in increased expression of CYP1A2 mRNA12107646|2178402
C007738fluoranthene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
C007738fluoranthene"[1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of CYP1A2 mRNA"18711122
C007738fluoranthene[Benzo(a)pyrene co-treated with fluoranthene] affects the expression of CYP1A2 mRNA18711122
C041509fluorene[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA7750161
C041509fluorenefluorene results in increased activity of CYP1A2 protein8001243
D0150732-AcetylaminofluoreneCYP1A2 protein affects the metabolism of 2-Acetylaminofluorene2655891
D0150732-AcetylaminofluoreneCYP1A2 protein results in increased activity of 2-Acetylaminofluorene15450435
D0150732-AcetylaminofluoreneCYP1A2 results in increased hydrolysis of 2-Acetylaminofluorene2334931
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA16381673
D0150732-AcetylaminofluoreneNR1I2 protein affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1A2 mRNA]16381673
D0150732-Acetylaminofluorene2-Acetylaminofluorene analog results in decreased expression of CYP1A2 protein15916741
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in decreased expression of CYP1A2 protein15916741
D0150732-Acetylaminofluorene2-Acetylaminofluorene results in increased expression of CYP1A2 protein28245158
D024841FluoroquinolonesFluoroquinolones results in decreased activity of CYP1A2 protein19281725
D005485Flutamide[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Flutamide23397584
D005485FlutamideCYP1A2 protein results in increased susceptibility to Flutamide28762043
D005485FlutamideFlutamide results in increased expression of CYP1A2 mRNA24136188|2648540
D016666FluvoxamineCYP1A2 protein binds to and affects the metabolism of Fluvoxamine15905806
D016666FluvoxamineCYP1A2 protein results in increased susceptibility to Fluvoxamine18809730
D016666FluvoxamineEnoxacin inhibits the reaction [CYP1A2 protein affects the metabolism of Fluvoxamine]15905806
D016666FluvoxamineFluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of olanzapine]15545309
D016666FluvoxamineFluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of Theophylline]9029748
D016666FluvoxamineFluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of clozapine N-oxide]18809730
D016666FluvoxamineFluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of norclozapine]18809730
D016666FluvoxamineFluvoxamine results in decreased activity of CYP1A2 protein11763009|1554530
D016666Fluvoxamine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased chemical synthesis of 16-O-demethylaconitine metabolite21277363
D016666Fluvoxamine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D016666Fluvoxamine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in increased chemical synthesis of Aconitine metabolite21277363
D016666FluvoxamineFluvoxamine results in decreased activity of CYP1A2 protein26599973
D016666Fluvoxamine[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Caffeine26599973
D016666FluvoxamineFluvoxamine results in decreased activity of CYP1A2 protein11145498|9812137
D004397FonofosFonofos inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
D004397FonofosFonofos inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
D004397FonofosFonofos results in decreased activity of CYP1A2 protein16790556
C007768formononetinformononetin results in decreased activity of CYP1A2 protein26278343
C007768formononetinformononetin results in decreased activity of CYP1A2 protein26278343
D005632Fructosealpha-Tocopherol inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]26102010
D005632Fructose[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA26102010
D005632Fructosetetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]26102010
C069837fullerene C60fullerene C60 results in decreased expression of CYP1A2 mRNA19167457
C050131furafyllinefurafylline affects the reaction [CYP1A2 protein results in increased metabolism of Theobromine]10215755
C050131furafylline"furafylline inhibits the reaction [CYP1A2 protein results in increased hydroxylation of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]"8020169
C050131furafyllinefurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-xylene]8558417
C050131furafyllinefurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Oxazines]12569440
C050131furafyllinefurafylline inhibits the reaction [[CYP1A2 protein results in increased metabolism of Oxazines] which results in increased chemical synthesis of Oxazines]23850985
C050131furafyllinefurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]16049126|2385098
C050131furafyllinefurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
C050131furafyllinefurafylline inhibits the reaction [CYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide]19053182
C050131furafyllinefurafylline inhibits the reaction [CYP1A2 protein results in increased oxidation of clopidogrel]19812348
C050131furafyllinefurafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C050131furafyllinefurafylline results in decreased activity of CYP1A2 protein12467917|1281495
C050131furafylline"[furafylline results in decreased activity of CYP1A2 protein] which results in decreased susceptibility to 2-amino-9H-pyrido(2,3-b)indole"23898916
C050131furafylline[furafylline results in decreased activity of CYP1A2 protein] which results in decreased susceptibility to 4-biphenylamine23898916
C050131furafyllinefurafylline results in decreased hydroxylation of and results in decreased activity of CYP1A2 protein9202738
C050131furafyllinefurafylline results in decreased activity of CYP1A2 protein15766918
C050131furafyllinefurafylline results in decreased activity of CYP1A2 protein15766918
C050131furafylline[furafylline results in decreased activity of CYP1A2 protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]21932800
C050131furafylline"[furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of AHR protein]"22491429
C050131furafylline"[furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [6-methyl-1,3,8-trichlorodibenzofuran results in increased activity of AHR protein]"22491429
C050131furafylline[furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [beta-Naphthoflavone results in increased activity of AHR protein]22491429
C050131furafyllinefurafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C050131furafyllinefurafylline results in decreased activity of CYP1A2 protein12814958|1587949
C050131furafylline[furafylline results in decreased activity of CYP1A2 protein] which results in decreased glutathionylation of Duloxetine Hydrochloride20669986
C050131furafyllinefurafylline results in decreased activity of CYP1A219053182
C050131furafyllinefurafylline results in decreased activity of CYP1A2 protein15507517|1579945
C039281furanfuran results in decreased expression of CYP1A2 mRNA25539665
C038958gadolinium chloridegadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP1A2 protein]18202523
C037032galangingalangin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17090139
C037032galangingalangin results in decreased activity of CYP1A2 protein20806393|2105393
C037556gamma-valerolactonegamma-valerolactone results in decreased activity of CYP1A2 protein15916432
D015248GemfibrozilGemfibrozil results in decreased activity of CYP1A2 protein26599973
D015248Gemfibrozil[Gemfibrozil results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine26599973
D019833GenisteinCYP1A2 protein results in increased chemical synthesis of Genistein12814970
D019833GenisteinCYP1A2 protein results in increased metabolism of Genistein12814970
D019833GenisteinGenistein results in decreased activity of CYP1A2 protein20806393|2105393
D019833GenisteinGenistein results in decreased expression of CYP1A2 mRNA24967385
D019833GenisteinCYP1A2 protein results in increased hydroxylation of Genistein15587933
C014568genkwaninCYP1A2 protein results in increased metabolism of genkwanin19666078
C048393germacronegermacrone results in decreased activity of CYP1A2 protein23850985
C033273Gestodene[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein16198659
C033273Gestodene[[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein] which results in decreased metabolism of tizanidine16198659
C033273GestodeneGestodene inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
C063170Ginkgo biloba extractGinkgo biloba extract results in decreased activity of CYP1A2 protein15147983
C063170Ginkgo biloba extractGinkgo biloba extract results in increased expression of CYP1A2 mRNA19034627
C063170Ginkgo biloba extractGinkgo biloba extract results in increased expression of and results in increased activity of CYP1A2 protein18421621
C063170Ginkgo biloba extractGinkgo biloba extract results in increased expression of CYP1A2 mRNA18421621
C477042ginkgolide Aginkgolide A results in increased activity of CYP1A2 protein18421621
C477042ginkgolide Aginkgolide A results in increased expression of CYP1A2 mRNA18421621
C045856ginkgolide Bginkgolide B results in increased expression of and results in increased activity of CYP1A2 protein18421621
C045856ginkgolide Bginkgolide B results in increased expression of CYP1A2 mRNA18421621
C119493glucoerucinglucoerucin results in increased expression of CYP1A2 protein20833222
C119494glucoraphaninglucoraphanin results in increased expression of CYP1A2 protein20833222
C023847Glu-P-2CYP1A2 protein affects the metabolism of Glu-P-22655891
C023847Glu-P-2CYP1A2 protein results in increased metabolism of and results in increased susceptibility to Glu-P-228160022
C023847Glu-P-2Glu-P-2 results in increased expression of CYP1A2 mRNA27644595
D005978Glutathione[CYP1A2 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac24246759
D005978Glutathione"[CYP1A2 protein co-treated with NADP co-treated with Glutathione] results in increased glutathionylation of and results in increased activity of 7-methoxy-N-((6-(3-methylisothiazol-5-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)methyl)-1,5-naphthyridin-4-amine"20825217
D005978GlutathioneGlutathione inhibits the reaction [myristicin results in decreased activity of CYP1A2 protein]26091900
D006034Glycyrrhetinic Acid[brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein21800547
C465546green tea extract AR25green tea extract AR25 promotes the reaction [FOS protein binds to CYP1A2 enhancer]10620351
C465546green tea extract AR25green tea extract AR25 promotes the reaction [JUND protein binds to CYP1A2 enhancer]10620351
C465546green tea extract AR25green tea extract AR25 promotes the reaction [JUN protein binds to CYP1A2 enhancer]10620351
D006118GriseofulvinGriseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]9029748
D006118GriseofulvinGriseofulvin affects the expression of CYP1A2 mRNA12735108
D006145GuanethidineGuanethidine inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]16510159
C473027GW 3965GW 3965 results in increased expression of CYP1A2 mRNA23041609
D006202Hair DyesCYP1A2 protein polymorphism affects the susceptibility to Hair Dyes12663508
D055768Halogenated Diphenyl EthersHalogenated Diphenyl Ethers results in increased expression of CYP1A218774282
D006427HeminHemin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]22159698
D006427HeminHemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein]26747958
D006427HeminHemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of CYP1A2 protein]26747958
D006427Hemin[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in decreased expression of CYP1A2 protein26747958
C481602heptylparabenheptylparaben results in decreased activity of CYP1A2 protein27432241
D006571Heterocyclic CompoundsCYP1A2 protein affects the metabolism of and results in increased activity of Heterocyclic Compounds12505289
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of CYP1A2 mRNA2856071
D006581HexachlorobenzeneHexachlorobenzene results in increased expression of CYP1A2 protein10696772|2539049
C012348higenamine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA28843594
D017313FenretinideFenretinide results in increased expression of CYP1A2 mRNA28973697
C042686humulenehumulene results in decreased activity of CYP1A2 protein29074051
C050426huperzine ACYP1A2 protein results in increased metabolism of huperzine A12586202
D006830HydralazineHydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D006830HydralazineHydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D006861Hydrogen PeroxideCYP1A2 protein results in increased abundance of Hydrogen Peroxide25061110
D047348Hydrolyzable Tannins[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA28843594
D047348Hydrolyzable TanninsHydrolyzable Tannins results in decreased activity of CYP1A2 protein12749824
C058309hypaconitineCYP1A2 protein results in increased metabolism of hypaconitine21550385
C082585iberiniberin results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein]22664424
D007052IbuprofenIbuprofen results in decreased expression of CYP1A2 mRNA25596134
D007069IfosfamideIfosfamide results in increased expression of CYP1A2 mRNA25596134
D007099ImipramineCYP1A2 protein affects the metabolism of Imipramine15286053
D007099ImipramineCYP1A2 protein results in decreased methylation of and results in increased activity of Imipramine15922009
D007099ImipramineCYP1A2 protein results in increased metabolism of Imipramine11714871
D007099ImipramineImipramine inhibits the reaction [resveratrol results in decreased activity of CYP1A2 protein]11714871
D007099ImipramineOrganophosphorus Compounds inhibits the reaction [CYP1A2 protein results in decreased methylation of and results in increased activity of Imipramine]15922009
C002921imipramine N-oxideCYP1A2 protein results in increased abundance of imipramine N-oxide27320963
C031534imperatorinimperatorin results in increased expression of CYP1A2 protein18692084
C013352indacrinoneindacrinone analog results in decreased activity of CYP1A2 protein15916432
C093582indanindan results in decreased activity of CYP1A2 protein15916432
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in increased expression of CYP1A2 mRNA"17253728
D007200IndicanIndican results in increased expression of CYP1A2 mRNA20000589
C027185indirubinindirubin results in increased expression of CYP1A2 mRNA15056799
C016517indole-3-carbinolindole-3-carbinol results in increased expression of CYP1A2 mRNA28357125
C016517indole-3-carbinolindole-3-carbinol results in increased expression of CYP1A222328411
C016517indole-3-carbinolAcetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]22129741
C016517indole-3-carbinolindole-3-carbinol affects the expression of CYP1A2 mRNA21396975
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA22129741
C016517indole-3-carbinolindole-3-carbinol results in increased activity of CYP1A212147290
C016517indole-3-carbinolindole-3-carbinol results in increased activity of CYP1A2 protein12147290
C016517indole-3-carbinolindole-3-carbinol results in increased expression of CYP1A222328411|9806166
C016517indole-3-carbinolindole-3-carbinol results in increased expression of CYP1A2 protein8384853
D007211IndolesCYP1A2 protein results in increased glutathionylation of Indoles22429462
C075954indolo(3,2-b)carbazole"indolo(3,2-b)carbazole results in increased expression of CYP1A2 mRNA"12419834
D007213IndomethacinTLR4 protein affects the reaction [Indomethacin results in decreased activity of CYP1A2 protein]12927920
D007213IndomethacinIndomethacin results in decreased expression of CYP1A2 mRNA16771604
C015293indopanindopan analog results in decreased activity of CYP1A2 protein26599973
C015293indopan[indopan analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C015293indopanindopan results in decreased activity of CYP1A2 protein26599973
C015293indopan[indopan results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D007505Iron-Dextran ComplexIron-Dextran Complex inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]9443932
D007505Iron-Dextran ComplexIron-Dextran Complex results in decreased activity of CYP1A2 protein9443932
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine results in decreased activity of CYP1A2 protein11465391
C549713isocarbophosCYP1A2 protein results in increased metabolism of and results in decreased sulfation of and affects the activity of isocarbophos24752505
C055542isoimperatorinCYP1A2 protein results in increased oxidation of isoimperatorin25500267
C040920isoliquiritigenin"isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"25110319
C040920isoliquiritigeninisoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]25110319
C018326isomalathionisomalathion results in decreased expression of CYP1A2 mRNA24333466
C015304isopimpinellinisopimpinellin results in increased expression of CYP1A2 protein18692084
C518329isopropyl-9H-thioxanthen-9-oneisopropyl-9H-thioxanthen-9-one results in increased expression of CYP1A2 mRNA20558275
D007545IsoproterenolIsoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D007545IsoproterenolIsoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15710352
D007545IsoproterenolPropranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]15710352
C028904isoproturonisoproturon results in increased activity of CYP1A2 protein22310298
C028904isoproturonisoproturon results in increased expression of CYP1A2 mRNA22310298
C028904isoproturonisoproturon results in decreased activity of CYP1A2 protein18420780
C016527isoquercitrin[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA20033131
C015959isosafroleisosafrole results in increased expression of CYP1A2 mRNA8722114
C015959isosafroleisosafrole inhibits the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane]12062927
C015959isosafroleisosafrole results in decreased activity of CYP1A2 protein12062927
C015959isosafroleisosafrole results in increased expression of CYP1A2 mRNA11285323
C015959isosafroleisosafrole results in increased expression of CYP1A23377821
C512910isoxanthohumolisoxanthohumol results in increased expression of CYP1A2 mRNA15672752
D017275IsradipineIsradipine results in increased expression of CYP1A2 mRNA27732883
D007559IvermectinIvermectin results in increased expression of CYP1A2 mRNA24998875
C006552kaempferolkaempferol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21256954
C006552kaempferolkaempferol results in decreased activity of CYP1A2 protein20806393|2105393
C006552kaempferolkaempferol results in increased expression of CYP1A2 mRNA19034627
C006552kaempferolkaempferol results in increased expression of and results in increased activity of CYP1A2 protein18421621
C006552kaempferolkaempferol results in increased expression of CYP1A2 mRNA18421621
C477388KC 500KC 500 results in increased expression of CYP1A2 mRNA12117779
D007654KetoconazoleKetoconazole results in increased expression of CYP1A2 protein7986207
D007654KetoconazoleKetoconazole affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D007654KetoconazoleKetoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
D007654KetoconazoleKetoconazole results in decreased activity of CYP1A2 protein15618748|1591643
D007654KetoconazoleKetoconazole results in increased expression of CYP1A2 mRNA25000292
D007654KetoconazoleKetoconazole results in increased expression of CYP1A2 protein25000292
D007654KetoconazoleKetoconazole inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]1567206
D007654KetoconazoleKetoconazole results in decreased activity of CYP1A2 protein18420780
D007654KetoconazoleKetoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]19858067
D007654KetoconazoleKetoconazole results in decreased activity of CYP1A2 protein12814958|1587949
C099406L 742694L 742694 affects the expression of CYP1A2 mRNA15102944
D064747LansoprazoleLansoprazole results in increased expression of CYP1A2 mRNA12623754
D064747LansoprazoleLansoprazole results in increased expression of CYP1A2 protein8169844|9744552
D064747LansoprazoleLansoprazole results in increased expression of CYP1A2 mRNA25626140
D064747LansoprazoleLansoprazole results in increased expression of CYP1A2 protein14550749|9152597
D064747LansoprazoleLansoprazole results in increased expression of CYP1A28930576
C476223laquinimodlaquinimod analog results in increased expression of CYP1A2 mRNA28433708
D007854LeadLead affects the expression of CYP1A2 mRNA23631153
C017461lead nitratelead nitrate results in decreased activity of CYP1A2 protein11162773
C017461lead nitrate"lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 mRNA]"8902619
C017461lead nitrate"lead nitrate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1A2 protein]"8902619
C017461lead nitrate"lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 mRNA]"8902619
C017461lead nitrate"lead nitrate inhibits the reaction [2-amino-3-methyl-9H-pyrido(2,3-b)indole results in increased expression of CYP1A2 protein]"8902619
C017461lead nitratelead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 mRNA]8902619
C017461lead nitratelead nitrate inhibits the reaction [2-methoxy-4-aminoazobenzene results in increased expression of CYP1A2 protein]8902619
C017461lead nitratelead nitrate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]8902619
C017461lead nitratelead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]8902619
C017461lead nitratelead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]8902619
C017461lead nitratelead nitrate results in decreased expression of and results in decreased activity of CYP1A2 protein8902619
C045463leflunomideleflunomide results in increased expression of CYP1A2 mRNA28988120
C045463leflunomideleflunomide results in increased expression of CYP1A2 mRNA24136188
C052901lemongrass oillemongrass oil affects the expression of CYP1A2 mRNA25976427
C052901lemongrass oillemongrass oil results in increased expression of CYP1A2 mRNA25660481
D007912LentinanLentinan results in decreased expression of CYP1A215630237
C011896lephetamineCYP1A2 protein results in decreased alkylation of lephetamine26276083
C070840licochalcone Alicochalcone A results in decreased activity of CYP1A2 protein26100226
D008012LidocaineCYP1A2 protein affects the metabolism of Lidocaine15447735
D001556LindaneLindane results in increased activity of CYP1A2 protein12842176|1664153
D001556LindaneLindane results in increased expression of and results in increased activity of CYP1A2 protein18486174
D001556LindaneLindane results in increased expression of CYP1A2 mRNA17919674|1798429
D001556LindaneLindane results in increased expression of CYP1A2 protein12842176|1791967
D001556LindaneMethylcholanthrene promotes the reaction [Lindane results in increased expression of and results in increased activity of CYP1A2 protein]18486174
D001556LindanePhenobarbital promotes the reaction [Lindane results in increased expression of and results in increased activity of CYP1A2 protein]18486174
C440499lipopolysaccharide, Escherichia coli O111 B4"lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of CYP1A2 mRNA"26220752
D008070LipopolysaccharidesLipopolysaccharides inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]22466549
D008070LipopolysaccharidesClenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15710352
D008070LipopolysaccharidesColforsin inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15710352
D008070LipopolysaccharidesIsoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15710352
D008070LipopolysaccharidesLipopolysaccharides results in decreased activity of CYP1A2 protein15542068|1571035
D008070LipopolysaccharidesN-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15542068
D008070LipopolysaccharidesPropranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]15710352
D008070LipopolysaccharidesPropranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]15710352
D008095Lithocholic AcidLithocholic Acid results in decreased activity of CYP1A2 protein18420780
D008095Lithocholic AcidCYP1A2 protein results in increased metabolism of Lithocholic Acid18039809
D008095Lithocholic Acid[CYP1A2 protein results in increased metabolism of Lithocholic Acid] which results in increased chemical synthesis of Lithocholic Acid analog18039809
D008152LoxapineCYP1A2 results in increased metabolism of Loxapine21826677
C015329lycopenelycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA]26775023
C005498magnololmagnolol results in decreased activity of CYP1A2 protein19140158
D008294MalathionCYP1A2 protein affects the metabolism of Malathion15557345
D008294MalathionMalathion results in increased expression of CYP1A2 mRNA22310298
D008344ManebAcetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D008344ManebAcetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]23159886
D008344Maneb[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein23159886
D008344Maneb[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA23159886
D008344ManebSilymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D008344ManebSilymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]23159886
C501277Mangifera indica extractMangifera indica extract results in decreased activity of CYP1A2 protein22815239
C501277Mangifera indica extractMangifera indica extract results in increased expression of CYP1A2 mRNA22815239
C501277Mangifera indica extractMangifera indica extract results in decreased activity of CYP1A2 protein18053976
C013592mangiferinmangiferin results in decreased activity of CYP1A2 protein22815239
C013592mangiferinmangiferin results in increased expression of CYP1A2 mRNA22815239
C013592mangiferinmangiferin results in decreased activity of CYP1A2 protein18053976
D008463MebendazoleMebendazole results in increased expression of CYP1A2 protein12841937
D008463MebendazoleMebendazole results in increased expression of CYP1A2 protein12841937
D008468MeclizineMeclizine inhibits the reaction [[Phenobarbital results in increased activity of NR1I3 protein] which results in increased expression of CYP1A2 mRNA]15272053
D008468Meclizine[Meclizine binds to and results in increased activity of NR1I3 protein] which results in increased expression of CYP1A2 mRNA15272053
D008528Mefenamic AcidCYP1A2 protein results in increased glutathionylation of Mefenamic Acid analog25372302
D008528Mefenamic AcidCYP1A2 protein results in increased hydroxylation of Mefenamic Acid25372302
D008528Mefenamic AcidMefenamic Acid results in decreased activity of CYP1A2 protein18816299
D008550MelatoninCYP1A2 protein affects the metabolism of Melatonin15626586|1582491
D008550MelatoninCYP1A2 protein results in decreased methylation of Melatonin15616152
D008550MelatoninCYP1A2 protein results in increased hydroxylation of Melatonin15616152|2263405
D008550MelatoninCYP1A2 protein results in increased metabolism of Melatonin17565714
D008550MelatoninMelatonin inhibits the reaction [CYP1A2 protein results in increased hydrolysis of Benzo(a)pyrene]19919601
D008550MelatoninMelatonin results in decreased activity of CYP1A2 protein19919601
D008550Melatonin[ABCB6 gene mutant form results in decreased expression of CYP1A2 mRNA] inhibits the reaction [CYP1A2 protein results in increased metabolism of Melatonin]25623066|2562306
D008550Melatonin[ABCB6 gene mutant form results in decreased expression of CYP1A2 protein] inhibits the reaction [CYP1A2 protein results in increased metabolism of Melatonin]25623066
D008550MelatoninCYP1A2 protein results in increased metabolism of Melatonin25623066
D008550Melatonin[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of CYP1A2 mRNA20033131
D008558MelphalanMelphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D008558MelphalanMelphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D008627Mercuric ChlorideMercuric Chloride results in decreased activity of CYP1A2 protein11162773
D008628MercuryMercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23231920
D008628MercuryMercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]22579925
D008628MercuryMercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]22579925
D008628MercuryMercury results in increased activity of CYP1A2 protein22579925
D008687MetforminMetformin results in increased expression of CYP1A2 mRNA19022234
D008687MetforminMetformin results in decreased expression of CYP1A2 mRNA25596134
D008691MethadoneCYP1A2 protein affects the metabolism of Methadone11145498
D008694MethamphetamineCYP1A2 protein affects the metabolism of Methamphetamine metabolite16038959
D008715Methionine"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Methionine deficiency co-treated with Choline deficiency] results in increased expression of CYP1A2 mRNA"28973532
D008715Methionine[LEP gene mutant form results in increased susceptibility to [Methionine co-treated with Choline]] which results in decreased expression of CYP1A2 mRNA27712037
D008715Methionine[LEP gene mutant form results in increased susceptibility to [Methionine co-treated with Choline]] which results in decreased expression of CYP1A2 protein27712037
D008715Methionine"[Methionine deficiency co-treated with Choline deficiency co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased expression of CYP1A2 mRNA"28163111
D003915DextromethorphanCYP1A2 protein affects the metabolism of Dextromethorphan15199075
D008727MethotrexateMethotrexate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D008727MethotrexateMethotrexate results in decreased expression of CYP1A2 mRNA15120968
D008731MethoxychlorCYP1A2 protein results in decreased methylation of Methoxychlor12167570|1243379
D008731MethoxychlorCYP1A2 protein results in increased hydroxylation of Methoxychlor9047321
D008731MethoxychlorMethoxychlor results in increased expression of CYP1A2 mRNA21924250
D008731MethoxychlorESR1 protein promotes the reaction [Methoxychlor results in increased expression of CYP1A2 mRNA]21252393
D008731MethoxychlorMethoxychlor results in increased expression of CYP1A2 mRNA21252393
D008731MethoxychlorMethoxychlor results in increased expression of and results in increased activity of CYP1A2 protein12919727
D008732MethoxydimethyltryptaminesMethoxydimethyltryptamines analog results in decreased activity of CYP1A2 protein26599973
D008732Methoxydimethyltryptamines[Methoxydimethyltryptamines analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D008730MethoxsalenMethoxsalen results in decreased activity of CYP1A2 protein8819299
D008730MethoxsalenMethoxsalen results in decreased activity of CYP1A2 protein18420780
D008730MethoxsalenMethoxsalen results in decreased activity of CYP1A2 protein12814958|1587949
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 mRNA9364010
D008748MethylcholanthreneMethylcholanthrene results in increased activity of CYP1A2 protein16639589
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 protein16639589
D008748MethylcholanthreneAHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]15155550
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 mRNA15155550
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 protein15155550
D008748MethylcholanthreneAHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]20171196
D008748Methylcholanthrene[Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A2 mRNA15448115
D008748MethylcholanthreneDehydroepiandrosterone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]23603339
D008748Methylcholanthrene[Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]19022236
D008748MethylcholanthreneDexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]19022236
D008748MethylcholanthreneDexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]19022236
D008748MethylcholanthreneMethylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D008748MethylcholanthreneMethylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A2 mRNA]20067464
D008748MethylcholanthreneMethylcholanthrene results in increased activity of CYP1A2 protein19022236|1911856
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 mRNA12107646|1576988
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 protein15769886|1616784
D008748MethylcholanthreneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]19022236
D008748MethylcholanthreneNicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]20067464
D008748MethylcholanthreneAHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]6749129
D008748MethylcholanthreneAHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]6749129
D008748MethylcholanthreneCTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]25174530
D008748MethylcholanthreneCYP1A2 affects the susceptibility to Methylcholanthrene19772856
D008748Methylcholanthrene[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA21498875
D008748MethylcholanthreneMethylcholanthrene results in increased activity of CYP1A2 protein16639589|4054433
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 mRNA11356909|1154929
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 protein16167840|1663958
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 protein7701848
D008748Methylcholanthrenelead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]8902619
D008748MethylcholanthreneMethylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D008748MethylcholanthreneMethylcholanthrene promotes the reaction [CYP1A2 protein results in increased oxidation of Toluene]1994898
D008748MethylcholanthreneMethylcholanthrene promotes the reaction [Lindane results in increased expression of and results in increased activity of CYP1A2 protein]18486174
D008748MethylcholanthreneMethylcholanthrene results in increased activity of CYP1A2 protein15302093|1559011
D008748Methylcholanthrene[Methylcholanthrene results in increased activity of CYP1A2 protein] which results in increased oxidation of Uroporphyrinogens1617633
D008748MethylcholanthreneMethylcholanthrene results in increased expression of and results in increased activity of CYP1A2 protein15946133
D008748Methylcholanthrene"[[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole"11999409
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 mRNA10476907|1077264
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A2 protein11285323|1199940
D008748Methylcholanthreneprotocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]15302093
D008748MethylcholanthreneMethylcholanthrene results in increased expression of CYP1A215890479
D008752Methylene ChlorideMethylene Chloride affects the expression of CYP1A2 mRNA28392392
D012862SkatoleSkatole results in increased expression of CYP1A2 mRNA28571685
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased activity of CYP1A2 protein"24211539
D018817N-Methyl-3,4-methylenedioxyamphetamine"CYP1A2 affects the metabolism of N-Methyl-3,4-methylenedioxyamphetamine"21871945
C051786metolachlormetolachlor results in increased activity of CYP1A2 protein10813365
D008825MiconazoleMiconazole results in increased expression of CYP1A2 mRNA22262564
D015735Mifepristone[Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]19022236
D015735Mifepristone[Dexamethasone co-treated with Mifepristone] results in increased activity of CYP1A2 protein19022236
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]19022236
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]19022236
D015735MifepristoneMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]17690134
D016685MitomycinMitomycin results in decreased activity of CYP1A2 protein15696929
C001801mitragyninemitragynine results in increased activity of CYP1A2 protein23274770
C001801mitragyninemitragynine results in increased expression of CYP1A2 mRNA23274770
C001801mitragyninemitragynine results in increased expression of CYP1A2 protein23274770
C028577monobutyl phthalatemonobutyl phthalate results in decreased activity of CYP1A2 protein27432241
D008999MonocrotophosMonocrotophos results in increased expression of CYP1A2 protein21445290
C020300monomethylarsonic acidmonomethylarsonic acid results in increased expression of CYP1A2 mRNA17481689
C031448musk ketonemusk ketone results in increased expression of CYP1A2 mRNA9441723
C031448musk ketonemusk ketone results in increased activity of CYP1A2 protein10630706
C031448musk ketonemusk ketone results in increased expression of CYP1A2 protein10630706
C031447musk xylenemusk xylene metabolite results in increased expression of CYP1A2 mRNA9397191
C031447musk xylenemusk xylene results in increased expression of CYP1A2 mRNA9397191
C031447musk xylenemusk xylene results in increased activity of CYP1A2 protein10630706
C031447musk xylenemusk xylene results in increased expression of CYP1A2 protein10630706
D009173Mycophenolic AcidMycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]25929522
C005246myristicinCYP1A2 protein affects the oxidation of myristicin12523956
C005246myristicinGlutathione inhibits the reaction [myristicin results in decreased activity of CYP1A2 protein]26091900
C005246myristicinmyristicin results in decreased activity of CYP1A2 protein26091900
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of CYP1A2 mRNA"29244179
C560625N-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amineN-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]21493753
C534983N-(2-amino-3-methyl-n-butyl)-3-((bis-4-fluorophenyl)methoxy)tropaneCYP1A2 protein results in increased metabolism of N-(2-amino-3-methyl-n-butyl)-3-((bis-4-fluorophenyl)methoxy)tropane18425847
C104820N-(3-(aminomethyl)benzyl)acetamidineN-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]15542068
C554954N-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochlorideN-((3S)-1-azabicyclo(2.2.2)oct-3-yl)-1H-indazole-3-carboxamide hydrochloride results in increased expression of CYP1A2 mRNA28174063
C507425N-(4-cyano-benzo(b)thiophene-2-carbonyl)guanidineCYP1A2 protein results in increased hydroxylation of N-(4-cyano-benzo(b)thiophene-2-carbonyl)guanidine16857327
C028473N-acetyl-4-benzoquinoneimineCYP1A2 protein results in increased abundance of N-acetyl-4-benzoquinoneimine24661219
C028473N-acetyl-4-benzoquinoneimineCYP1A2 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine19679878
C028473N-acetyl-4-benzoquinoneimineCYP1A2 protein results in increased abundance of N-acetyl-4-benzoquinoneimine24552538
C028473N-acetyl-4-benzoquinoneimine[CYP1A2 results in increased oxidation of Acetaminophen] which results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine8861779
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CYP1A2 mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of CYP1A2 mRNA"25620056
C031721naphthalenenaphthalene analog results in decreased activity of CYP1A2 protein15916432
C031721naphthalenenaphthalene inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 2-hydroxyestradiol]16790556
C031721naphthalenenaphthalene inhibits the reaction [CYP1A2 protein results in increased metabolism of Estradiol]16790556
C031721naphthalenenaphthalene results in decreased activity of CYP1A2 protein15916432|1679055
C031721naphthalenenaphthalene results in decreased activity of CYP1A2 protein19563207
C501268naphtho(2,3-a)pyrene"naphtho(2,3-a)pyrene results in increased expression of CYP1A2 mRNA"17253728
D0150581-Naphthylisothiocyanate[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA27344345
D0150581-Naphthylisothiocyanate"[1-Naphthylisothiocyanate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] results in decreased expression of CYP1A2 protein"15598703
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of CYP1A2 protein15598703
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of CYP1A2 mRNA20551477
D0150581-Naphthylisothiocyanate"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 1-Naphthylisothiocyanate] results in decreased expression of CYP1A2 protein"15598703
C005273naringeninnaringenin results in decreased activity of CYP1A2 protein21053930
C005274naringinnaringin results in decreased activity of CYP1A2 protein21053930
C498045NCX 4040NCX 4040 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19542225
C498045NCX 4040NCX 4040 results in decreased activity of CYP1A2 protein19542225
C028787N-desmethyltamoxifenCYP1A2 protein results in increased metabolism of N-desmethyltamoxifen29285606
C028787N-desmethyltamoxifen"[CYP1A2 protein results in increased metabolism of N-desmethyltamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"29285606
C051752nefazodonenefazodone results in increased expression of CYP1A2 mRNA24136188
C000598690N-ethyl-1,2-diphenylethylamine"CYP1A2 protein results in decreased alkylation of N-ethyl-1,2-diphenylethylamine"26276083
C026385n-hexaneCYP1A2 protein results in increased hydroxylation of n-hexane16484137
C026385n-hexanediallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein]28115069
C026385n-hexanen-hexane results in increased expression of and results in increased activity of CYP1A2 protein28115069
D009529NicardipineMethylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A2 mRNA]20067464
D009529NicardipineNicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]20067464
D009529NicardipineNicardipine results in decreased activity of CYP1A2 protein15863898
D009529NicardipineNicardipine results in increased expression of CYP1A2 mRNA20067464
D009532NickelNickel results in decreased expression of CYP1A2 mRNA24768652
C022838nickel chloridenickel chloride results in decreased expression of CYP1A2 protein21784029
C028007nickel monoxidenickel monoxide results in decreased expression of CYP1A2 mRNA19167457
D009534NiclosamideNiclosamide results in decreased activity of CYP1A2 protein11124226
D009538NicotineNicotine results in decreased activity of CYP1A2 protein15916432
D009538NicotineNicotine results in increased expression of CYP1A2 protein11849738
D009538NicotineNicotine results in decreased expression of CYP1A2 mRNA26463278
D009543NifedipineNifedipine results in decreased activity of CYP1A2 protein10805063
D009543NifedipineNifedipine results in decreased activity of CYP1A2 protein18420780
D009543NifedipineNifedipine inhibits the reaction [CYP1A2 protein results in increased metabolism of 3-cyano-7-ethoxycoumarin]19858067
C012655nimesulideCYP1A2 protein results in increased glutathionylation of nimesulide26524229
C012655nimesulidenimesulide results in decreased expression of CYP1A2 mRNA24136188
D015737NisoldipineNisoldipine results in decreased activity of CYP1A2 protein10805063
C000598691N-isopropyl-1,2-diphenylethylamine"CYP1A2 protein results in decreased alkylation of N-isopropyl-1,2-diphenylethylamine"26276083
C008625nitroanilinenitroaniline analog results in increased activity of CYP1A2 protein9545601
C008625nitroanilinenitroaniline analog results in increased expression of CYP1A2 mRNA9545601
C008625nitroanilinenitroaniline analog results in increased expression of CYP1A2 protein9545601
D009582NitrofurantoinNitrofurantoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C041150N-methyl-7H-dibenzo(c,g)carbazole"CYP1A2 protein affects the metabolism of and results in increased activity of N-methyl-7H-dibenzo(c,g)carbazole"15534862
C062567N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amideCYP1A2 protein results in increased activity of N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide15725615
C468271N-methyl-N-benzylnitrosamineN-methyl-N-benzylnitrosamine results in decreased activity of CYP1A2 protein12222751
C578955N,N-diallyl-5-methoxytryptamine"N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP1A2 protein"26599973
C578955N,N-diallyl-5-methoxytryptamine"[N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin"26599973
C578955N,N-diallyl-5-methoxytryptamine"N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP1A2 protein"26599973
C578955N,N-diallyl-5-methoxytryptamine"[N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Caffeine"26599973
C574385N,N-didesmethyl-4-hydroxytamoxifen"CYP1A2 protein results in increased metabolism of N,N-didesmethyl-4-hydroxytamoxifen"29285606
C574385N,N-didesmethyl-4-hydroxytamoxifen"[CYP1A2 protein results in increased metabolism of N,N-didesmethyl-4-hydroxytamoxifen] which results in increased abundance of N,N-didesmethyl-4-hydroxytamoxifen"29285606
C454677N,N-diethyl-3-hydroxymethylbenzamide"CYP1A2 protein results in increased chemical synthesis of N,N-diethyl-3-hydroxymethylbenzamide"11854147
C033695N,N-diisopropyltryptamine"N,N-diisopropyltryptamine analog results in decreased activity of CYP1A2 protein"26599973
C033695N,N-diisopropyltryptamine"[N,N-diisopropyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin"26599973
C008661nobiletinCYP1A2 protein results in increased metabolism of nobiletin22743247
C058272norclozapine[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of norclozapine11151749
C058272norclozapineCYP1A2 protein results in increased chemical synthesis of norclozapine18809730
C058272norclozapineFluvoxamine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of norclozapine]18809730
C058272norclozapineCYP1A2 protein results in increased metabolism of norclozapine12969762
D009643NorfloxacinNorfloxacin binds to CYP1A2 protein8905919
D009643NorfloxacinNorfloxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]8905919
C017576norgestimate[Ethinyl Estradiol co-treated with norgestimate] results in decreased activity of CYP1A2 protein16291717
C010262norharmanCYP1A2 protein affects the metabolism of [norharman co-treated with aniline]15279827
D009661NortriptylineNortriptyline results in increased metabolism of CYP1A2 protein18359012
C072936notoginsenoside R1notoginsenoside R1 results in decreased activity of CYP1A2 protein25834921
C064976O(6)-benzylguanineO(6)-benzylguanine inhibits the reaction [CYP1A2 protein affects the metabolism of Phenacetin]11751525
C064976O(6)-benzylguanineO(6)-benzylguanine inhibits the reaction [CYP1A2 protein results in increased metabolism of Dacarbazine metabolite]11751525
C064976O(6)-benzylguanineO(6)-benzylguanine results in decreased activity of CYP1A2 protein11751525
C064976O(6)-benzylguanineCYP1A2 protein affects the oxidation of O(6)-benzylguanine11751525
C464660obeticholic acidobeticholic acid inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of Acetaminophen]27939613
C464660obeticholic acidobeticholic acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]27939613
C464660obeticholic acidobeticholic acid results in decreased activity of CYP1A2 protein27939613
C464660obeticholic acidobeticholic acid results in decreased expression of CYP1A2 mRNA27939613
C025589ochratoxin ACYP1A2 protein results in increased susceptibility to ochratoxin A11189750|2178165
C025589ochratoxin Aochratoxin A results in increased expression of CYP1A2 mRNA21834667
C014138octachlorostyreneoctachlorostyrene results in increased activity of CYP1A2 protein19525444
C014138octachlorostyreneoctachlorostyrene results in increased expression of CYP1A2 mRNA19525444
D019787Linoleic AcidLinoleic Acid results in decreased activity of CYP1A2 protein16978661
D015242Ofloxacin[Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]11408986
D019319Okadaic AcidCYP1A2 protein results in increased metabolism of and results in increased susceptibility to Okadaic Acid26374342
D019319Okadaic AcidCYP1A2 protein results in increased metabolism of and results in increased susceptibility to Okadaic Acid26374342
C076029olanzapineCYP1A2 protein affects the metabolism of olanzapine15545309|1588314
C076029olanzapineFluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of olanzapine]15545309
D009828Oleanolic AcidOleanolic Acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]15043991
D009828Oleanolic AcidOleanolic Acid results in decreased activity of CYP1A2 protein15043991
D009828Oleanolic AcidOleanolic Acid results in decreased expression of CYP1A2 mRNA23948738
D009828Oleanolic AcidOleanolic Acid results in decreased expression of CYP1A2 mRNA18706400
C011521olivacineCYP1A2 protein affects the metabolism of olivacine analog14709624
C011521olivacineolivacine analog results in increased expression of and results in increased activity of CYP1A2 protein14709624
C026209oltipraz"oltipraz inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline]"10775323
C026209oltiprazoltipraz metabolite results in decreased activity of CYP1A2 protein10775323
C026209oltiprazoltipraz results in decreased activity of CYP1A2 protein10775323
C026209oltiprazNFE2L2 protein affects the reaction [oltipraz results in increased expression of CYP1A2 mRNA]22496397
C026209oltiprazoltipraz results in increased expression of CYP1A2 mRNA22496397
C026209oltiprazCYP1A2 protein affects the metabolism of oltipraz15831204|1592076
C026209oltiprazoltipraz results in increased activity of CYP1A2 protein8625305
C026209oltiprazoltipraz results in increased expression of CYP1A2 mRNA8625305
D009853OmeprazoleAHR protein affects the susceptibility to [Omeprazole results in increased expression of CYP1A2 mRNA]20171196
D009853OmeprazoleOmeprazole results in decreased activity of CYP1A2 protein16035375
D009853OmeprazoleOmeprazole results in increased activity of CYP1A2 promoter18502397
D009853OmeprazoleOmeprazole results in increased activity of CYP1A2 protein19118567|1923059
D009853OmeprazoleOmeprazole results in increased expression of and results in increased activity of CYP1A2 protein15802389
D009853OmeprazoleOmeprazole results in increased expression of CYP1A2 mRNA12040753|1262375
D009853OmeprazoleOmeprazole results in increased expression of CYP1A2 protein12841937|2178402
D009853Omeprazole[Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin22524704
D009853OmeprazoleOmeprazole results in decreased activity of CYP1A2 protein18420780
D009853Omeprazole[Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA22687989
D009853OmeprazoleOmeprazole results in increased expression of CYP1A2 mRNA19118567|2562614
D009853OmeprazoleOmeprazole results in increased expression of CYP1A2 protein9152597
D009853OmeprazoleOmeprazole results in increased expression of CYP1A28930576
D017294OndansetronCYP1A2 protein affects the metabolism of Ondansetron15286053
C016340o,p'-DDT"o,p'-DDT results in increased expression of CYP1A2 mRNA"21924250
C016340o,p'-DDT"o,p'-DDT affects the expression of CYP1A2 mRNA"18925944
D009943Organophosphorus CompoundsOrganophosphorus Compounds inhibits the reaction [CYP1A2 protein results in decreased methylation of and results in increased activity of Imipramine]15922009
D009943Organophosphorus CompoundsOrganophosphorus Compounds results in decreased activity of CYP1A2 protein17936932
D016566Organoselenium CompoundsOrganoselenium Compounds binds to and results in decreased activity of CYP1A2 protein21732699
D009966OrphenadrineOrphenadrine inhibits the reaction [CYP1A2 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]9241656
D009966OrphenadrineOrphenadrine inhibits the reaction [CYP1A2 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]9241656
D009966OrphenadrineOrphenadrine results in decreased activity of CYP1A2 protein9241656
D009966OrphenadrineOrphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D008939MitotaneMitotane results in increased expression of CYP1A2 mRNA25542188
C012466oxadiazonoxadiazon results in increased expression of CYP1A2 mRNA26710982
D010078OxazinesCYP1A2 protein results in increased metabolism of Oxazines12569440|2263405
D010078Oxazines[CYP1A2 protein results in increased metabolism of Oxazines] which results in increased chemical synthesis of Oxazines23669205|2385098
D010078OxazinesCYP1A2 protein results in increased oxidation of Oxazines21964418
D010078Oxazinesfurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Oxazines]12569440
D010078Oxazinesfurafylline inhibits the reaction [[CYP1A2 protein results in increased metabolism of Oxazines] which results in increased chemical synthesis of Oxazines]23850985
D010078Oxazinesperfluorooctane sulfonic acid inhibits the reaction [CYP1A2 protein results in increased oxidation of Oxazines]21964418
C011030oxfendazole[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA20033131
C011030oxfendazole[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of CYP1A2 mRNA20033131
C011030oxfendazole[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A2 mRNA20033131
C011030oxfendazole[oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA18754104
D010100OxygenCYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]]29180065
D010100OxygenCYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]]29180065
D010100OxygenCYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]]29180065
D010100OxygenCYP1A2 gene mutant form results in increased susceptibility to Oxygen29180065
D010100Oxygen[CYP1A2 gene mutant form results in increased susceptibility to Oxygen] which results in increased expression of NQO1 mRNA29180065
D010100OxygenOxygen deficiency affects the reaction [CYP1A2 protein results in increased metabolism of aristolochic acid I]26845733
D010100OxygenOxygen deficiency results in decreased expression of CYP1A2 mRNA19695866
D010100Oxygenbeta-Naphthoflavone promotes the reaction [Oxygen results in increased activity of CYP1A2 protein]21745492
D010100Oxygenbeta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A2 mRNA]21745492
D010100Oxygen[beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]28201809
D010100Oxygen[beta-Naphthoflavone results in increased expression of CYP1A2 protein] which results in decreased susceptibility to Oxygen28201809
D010100OxygenOxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]29180065
D010100OxygenOxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]21745492
D010100OxygenOxygen results in increased activity of CYP1A2 protein21745492
D010100OxygenOxygen results in increased expression of CYP1A2 mRNA25703676
D010100OxygenHemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein]26747958
D010100OxygenHemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of CYP1A2 protein]26747958
D010100OxygenOxygen deficiency affects the reaction [CYP1A2 protein results in increased metabolism of aristolochic acid I]26845733
D010100Oxygen[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with Hemin] results in decreased expression of CYP1A2 protein26747958
D010100Oxygen[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP1A2 protein26747958
D010100Oxygen[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in decreased expression of CYP1A2 protein26747958
D010100Oxygen[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in decreased expression of CYP1A2 protein26747958
D010100OxygenOxygen inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]24657529
D010126OzoneAHR protein affects the reaction [Ozone results in increased expression of CYP1A2 mRNA]19536146
D010126OzoneAHR protein affects the reaction [Ozone results in increased expression of CYP1A2 protein]19536146
D010126OzoneOzone results in increased expression of CYP1A2 mRNA19536146
D010126OzoneOzone results in increased expression of CYP1A2 protein19536146
D010126OzoneOzone results in decreased expression of CYP1A2 mRNA16183385
D017239PaclitaxelPaclitaxel results in decreased activity of CYP1A2 protein19909766
D017239PaclitaxelPaclitaxel results in increased expression of CYP1A2 mRNA15585946
C064276pantoprazolepantoprazole results in increased expression of CYP1A2 mRNA25626140
C064276pantoprazolepantoprazole results in increased expression of CYP1A2 protein9152597
D010208PapaverinePapaverine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D010269ParaquatAcetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D010269ParaquatAcetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]23159886
D010269ParaquatAcetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D010269ParaquatAcetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]23159886
D010269Paraquat[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein23159886
D010269Paraquat[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA23159886
D010269ParaquatParaquat results in increased activity of CYP1A2 protein20888808
D010269ParaquatParaquat results in increased expression of and results in increased activity of CYP1A2 protein23159886
D010269ParaquatParaquat results in increased expression of CYP1A2 mRNA20888808|2315988
D010269ParaquatParaquat results in increased expression of CYP1A2 protein20888808
D010269ParaquatSilymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D010269ParaquatSilymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]23159886
D010269ParaquatSilymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D010269ParaquatSilymarin inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]23159886
D010278ParathionCYP1A2 protein affects the metabolism of Parathion12669189|1555734
D010278ParathionParathion results in increased expression of CYP1A2 mRNA26196221
D052638Particulate MatterParticulate Matter results in increased expression of CYP1A2 mRNA22352393|2421647
C410127PCB 180PCB 180 results in increased activity of CYP1A2 protein15743714
C410127PCB 180"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] promotes the reaction [AHR protein results in increased expression of CYP1A2 mRNA]"20961953
C410127PCB 180"[AHR protein co-treated with CYP1A2 protein] affects the susceptibility to [3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl co-treated with 2,3,3',4,4'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180]"20961953
C410127PCB 180CYP1A2 results in decreased susceptibility to PCB 18021571617
C410127PCB 180PCB 180 promotes the reaction [AHR protein results in increased expression of CYP1A2]20961953
C066957pelargonidinpelargonidin results in increased expression of CYP1A2 mRNA23419638
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of CYP1A2 mRNA19270788
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of CYP1A2 mRNA18243468
C003060pentachlorobenzenepentachlorobenzene results in increased expression of CYP1A2 protein10696772
D010416PentachlorophenolPentachlorophenol results in increased expression of CYP1A2 mRNA23892564
D010424PentobarbitalPentobarbital results in increased expression of CYP1A2 mRNA10064569
D010431PentoxifyllinePentoxifylline results in decreased activity of CYP1A2 protein11465391
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid inhibits the reaction [CYP1A2 protein results in increased oxidation of Oxazines]21964418
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of CYP1A2 mRNA20936131
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of CYP1A2 mRNA18281256
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of CYP1A2 mRNA20118188
C023036perfluorooctanoic acidPPARA promotes the reaction [perfluorooctanoic acid results in increased expression of CYP1A2 mRNA]20118188
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of CYP1A2 mRNA16221955|1916217
D010480PerhexilinePerhexiline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D026023PermethrinPermethrin results in increased expression of CYP1A2 mRNA21784029
D026023PermethrinPermethrin results in increased expression of CYP1A2 protein21784029
D010575PesticidesPesticides results in decreased activity of CYP1A2 protein17936932
D010615PhenacetinCYP1A2 protein affects the metabolism of Phenacetin15801540
D010615PhenacetinCYP1A2 protein results in increased oxidation of Phenacetin17097115
D010615Phenacetin"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [CYP1A2 protein results in decreased ethylation of Phenacetin]"8020169
D010615Phenacetin2-aminofluorene inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]28119166
D010615Phenacetin4-amino-2-phenoxymethanesulfonanilide promotes the reaction [CYP1A2 protein results in increased oxidation of Phenacetin]19053182
D010615Phenacetin[5-bromotryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[5-chlorotryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[5-fluoro-alpha-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[5-fluoro-alpha-methyltryptamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[5-fluorotryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[5-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[7-methyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin8-phenyltheophylline inhibits the reaction [CYP1A2 protein results in decreased ethylation of Phenacetin]11465391
D010615Phenacetin[alpha-naphthoflavone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615PhenacetinCYP1A2 protein affects the metabolism of Phenacetin11751525|1580154
D010615PhenacetinCYP1A2 protein results in decreased ethylation of Phenacetin11303964|1243379
D010615PhenacetinCYP1A2 protein results in increased metabolism of Phenacetin12401345|1246791
D010615Phenacetin[CYP1A2 protein results in increased metabolism of Phenacetin] which results in increased chemical synthesis of Acetaminophen19135037
D010615PhenacetinCYP1A2 protein results in increased oxidation of Phenacetin10985777|1128470
D010615PhenacetinCYP1A2 protein results in increased oxidation of Phenacetin analog11284709
D010615Phenacetin[Fluvoxamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetinfurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]16049126|2385098
D010615Phenacetin[indopan analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[indopan results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin[Methoxydimethyltryptamines analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetin"[N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin"26599973
D010615Phenacetin"[N,N-diisopropyltryptamine analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin"26599973
D010615PhenacetinO(6)-benzylguanine inhibits the reaction [CYP1A2 protein affects the metabolism of Phenacetin]11751525
D010615Phenacetinobeticholic acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]27939613
D010615PhenacetinOleanolic Acid inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]15043991
D010615Phenacetin[Omeprazole results in increased expression of CYP1A2 protein] which results in decreased alkylation of Phenacetin22524704
D010615PhenacetinPhenacetin results in increased activity of CYP1A2 protein15802386
D010615Phenacetin[Tryptamines analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
D010615Phenacetinzileuton inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]14570767
D010615PhenacetinCYP1A2 protein results in increased oxidation of Phenacetin9195021
D010615PhenacetinCYP1A2 protein affects the metabolism of Phenacetin15766918
D010615PhenacetinCYP1A2 protein affects the metabolism of Phenacetin15766918
D010615PhenacetinCYP1A2 protein affects the metabolism of Phenacetin15742976
D010615PhenacetinCYP1A2 protein results in increased metabolism of Phenacetin10445756
D010615PhenacetinPhenacetin inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]1567206
D010615PhenacetinPhenacetin results in increased expression of CYP1A2 protein15742976
D010615PhenacetinCYP1A2 protein affects the metabolism of Phenacetin15231049|1580154
D010615PhenacetinCYP1A2 protein results in decreased ethylation of Phenacetin11911841|1206436
D010615PhenacetinCYP1A2 protein results in increased metabolism of Phenacetin12222751|1765172
D010615Phenacetin[CYP1A2 protein results in increased metabolism of Phenacetin] which results in increased chemical synthesis of Acetaminophen28438436
D010615PhenacetinEnoxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]8905919
D010615PhenacetinNorfloxacin inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]8905919
C031181phenanthreneCYP1A2 protein results in increased metabolism of and results in increased activity of phenanthrene19766613
C031181phenanthreneCYP1A2 protein results in increased oxidation of phenanthrene27137136
C031181phenanthrene[CYP1A2 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol27137136
C031181phenanthrene[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA7750161
C031181phenanthreneCYP1A2 protein results in increased metabolism of and results in increased activity of phenanthrene19766613
C031181phenanthrenephenanthrene results in increased activity of CYP1A2 protein8001243
C031181phenanthrenephenanthrene results in decreased activity of CYP1A2 protein19563207
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased activity of CYP1A2 mRNA20442190
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of CYP1A2 protein20025923
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased expression of CYP1A2 mRNA15672752|2044219
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of CYP1A2 protein20025923
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]22664424
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in increased expression of CYP1A2 mRNA22664424
D010634PhenobarbitalPhenobarbital results in decreased expression of CYP1A2 mRNA19952500
D010634PhenobarbitalMeclizine inhibits the reaction [[Phenobarbital results in increased activity of NR1I3 protein] which results in increased expression of CYP1A2 mRNA]15272053
D010634PhenobarbitalPhenobarbital results in decreased activity of CYP1A2 protein19909766
D010634PhenobarbitalPhenobarbital results in increased activity of CYP1A2 protein19118567
D010634Phenobarbital[Phenobarbital results in increased activity of NR1I3 protein] which results in increased expression of CYP1A2 mRNA15272053
D010634PhenobarbitalPhenobarbital results in increased expression of CYP1A2 mRNA19118567|2225856
D010634Phenobarbitalciprofibrate inhibits the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]17962186
D010634PhenobarbitalMED1 protein promotes the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]16109766
D010634PhenobarbitalPhenobarbital affects the expression of CYP1A2 mRNA23091169
D010634Phenobarbital"[Phenobarbital co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1A2 mRNA"23681119
D010634PhenobarbitalPhenobarbital results in increased activity of CYP1A2 protein10064569
D010634PhenobarbitalPhenobarbital results in increased expression of CYP1A2 mRNA10064569|1610976
D010634PhenobarbitalPhenobarbital results in increased expression of CYP1A2 protein10064569|1869208
D010634Phenobarbitalpirinixic acid inhibits the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]17962186
D010634PhenobarbitalCholine deficiency promotes the reaction [Phenobarbital results in increased expression of CYP1A2 protein]18798224
D010634PhenobarbitalPhenobarbital promotes the reaction [Lindane results in increased expression of and results in increased activity of CYP1A2 protein]18486174
D010634PhenobarbitalPhenobarbital results in decreased expression of CYP1A2 mRNA11328961|1559606
D010634PhenobarbitalPhenobarbital results in increased expression of CYP1A2 mRNA20226384|2327357
D019800PhenolCYP1A2 protein affects the susceptibility to Phenol8242868
C008838phenthoatephenthoate results in increased expression of CYP1A2 mRNA22310298
D010656PhenylephrinePhenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D010656PhenylephrinePhenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16510159
D010656PhenylephrinePrazosin inhibits the reaction [Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]16510159
D010672Phenytoin[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Phenytoin23397584
D010695PhlorhizinPhlorhizin results in decreased expression of CYP1A2 mRNA22538082
C018637phoronephorone results in increased expression of CYP1A2 mRNA24494203
D010713PhosphatidylcholinesPhosphatidylcholines affects the activity of CYP1A2 protein15966743
C483858phosphatidylethanolaminephosphatidylethanolamine results in increased stability of and results in increased activity of CYP1A2 protein15966743
C008905physcionephyscione results in decreased activity of CYP1A2 protein27633141
C121565pifithrinpifithrin results in decreased activity of CYP1A2 protein16258175
C121565pifithrinpifithrin results in increased expression of CYP1A2 mRNA16258175
C121565pifithrinpifithrin results in increased expression of CYP1A2 protein16258175
C041648pimobendanCYP1A2 protein results in decreased methylation of pimobendan10611143
C448623pipermethystinepipermethystine results in increased expression of CYP1A2 protein17329236
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of CYP1A2 mRNA21784029
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of CYP1A2 protein21784029
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of CYP1A2 mRNA8722114|9233375
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of CYP1A2 protein9233375
D010882Piperonyl ButoxidePiperonyl Butoxide results in increased expression of CYP1A2 mRNA18544911|2073543
D010882Piperonyl ButoxideTriterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of CYP1A2 mRNA]18544911
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CYP1A2 mRNA19710929
C006253pirinixic acid[pirinixic acid co-treated with PPARA] results in decreased expression of CYP1A2 mRNA20813756
C006253pirinixic acidpirinixic acid inhibits the reaction [Phenobarbital results in increased expression of CYP1A2 mRNA]17962186
C006253pirinixic acidpirinixic acid results in decreased expression of CYP1A2 mRNA17962186|1846767
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of CYP1A2 mRNA]18467677|2005976
C006253pirinixic acidpirinixic acid results in decreased expression of CYP1A2 mRNA19162173
D010936Plant ExtractsPlant Extracts inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]11064004
D010936Plant ExtractsPlant Extracts results in decreased activity of CYP1A2 protein23850985
D010936Plant ExtractsPlant Extracts results in decreased expression of CYP1A2 mRNA19041297|2355793
D010936Plant ExtractsPlant Extracts results in increased activity of CYP1A2 protein15025748
D010936Plant ExtractsPlant Extracts results in increased expression of CYP1A2 mRNA15629189|2444630
D010936Plant ExtractsPlant Extracts results in decreased expression of CYP1A2 mRNA18158835
D010936Plant ExtractsPlant Extracts results in increased expression of CYP1A2 mRNA23262642
D010936Plant ExtractsPlant Extracts affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline]20096675
D010936Plant ExtractsPlant Extracts results in decreased activity of CYP1A2 protein15831081
D010936Plant ExtractsPlant Extracts results in increased expression of and results in increased activity of CYP1A2 protein15598702
D010936Plant ExtractsPlant Extracts results in increased expression of CYP1A2 mRNA19041297|2052177
D010936Plant ExtractsPlant Extracts results in increased expression of CYP1A2 protein20521779
D028321Plant PreparationsPlant Preparations results in decreased expression of CYP1A2 mRNA26530625
D028321Plant PreparationsPlant Preparations results in decreased activity of CYP1A2 protein27697540
D028321Plant PreparationsPlant Preparations results in decreased expression of CYP1A2 mRNA27697540
D028321Plant PreparationsPlant Preparations results in decreased expression of CYP1A2 protein24973489
D028321Plant PreparationsPlant Preparations results in increased expression of and results in increased activity of CYP1A2 protein15807986
D028321Plant PreparationsPlant Preparations results in increased expression of CYP1A2 mRNA21056093
D028321Plant PreparationsPlant Preparations results in increased expression of CYP1A2 protein21056093
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls results in increased expression of CYP1A2 mRNA9364010
D011078Polychlorinated Biphenyls"[Polychlorinated Biphenyls co-treated with Dibenzofurans, Polychlorinated] results in increased activity of CYP1A2 protein"17051818
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls results in increased activity of CYP1A2 protein15743714
D011078Polychlorinated BiphenylsCYP1A2 affects the susceptibility to Polychlorinated Biphenyls22935098
D000072317Polychlorinated Dibenzodioxins"[Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1A2 mRNA"17850846
D000072317Polychlorinated DibenzodioxinsPolychlorinated Dibenzodioxins results in decreased activity of CYP1A2 protein15659567
D000072317Polychlorinated DibenzodioxinsPolychlorinated Dibenzodioxins results in decreased activity of CYP1A2 protein15659567
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of CYP1A2 protein15824912
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased activity of CYP1A2 protein7750161
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of CYP1A2 mRNA7750161
D011084Polycyclic Aromatic HydrocarbonsPolycyclic Aromatic Hydrocarbons results in increased expression of CYP1A2 mRNA3379039
D011092Polyethylene GlycolsPolyethylene Glycols results in increased activity of CYP1A2 protein22558349
D011092Polyethylene GlycolsPolyethylene Glycols results in increased activity of CYP1A2 protein22558349
D059808PolyphenolsPolyphenols results in decreased expression of CYP1A2 mRNA19370779
D059808PolyphenolsPolyphenols results in decreased expression of CYP1A2 protein19370779
D059808PolyphenolsPolyphenols results in decreased activity of CYP1A2 protein15831081
D011134PolysaccharidesPolysaccharides results in decreased activity of CYP1A2 protein17827724
D011192Potassium DichromatePotassium Dichromate results in increased expression of CYP1A2 mRNA23608068
D017035PravastatinPravastatin results in decreased expression of CYP1A2 mRNA27225895
D017035PravastatinPravastatin results in decreased expression of CYP1A2 mRNA27225895
D011223PraziquantelCYP1A2 protein affects the metabolism of Praziquantel12920490
D011224PrazosinPrazosin inhibits the reaction [Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]16510159
D011224PrazosinPrazosin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D011224PrazosinPrazosin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]16510159
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]28428138
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of CYP1A2 mRNA27413110
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of CYP1A2 mRNA15596064|1916217
D011319PrimaquineCYP1A2 protein affects the metabolism of Primaquine12920490
D011319Primaquine[CYP1A2 protein results in increased expression of HBG2 protein] which affects the susceptibility to Primaquine19616568
D011319PrimaquineCYP1A2 protein results in increased metabolism of Primaquine19616568
D011319PrimaquinePrimaquine results in increased activity of CYP1A2 promoter18502397
D011319PrimaquinePrimaquine results in increased expression of CYP1A2 mRNA12451431|1262375
D011335ProadifenProadifen results in decreased activity of CYP1A2 protein15618748
C045362prochlorazprochloraz results in increased expression of CYP1A2 mRNA21784029
C045362prochlorazprochloraz results in increased expression of CYP1A2 protein21784029
C045362prochlorazprochloraz results in increased expression of CYP1A2 mRNA25182419
C024273profenofosprofenofos results in decreased activity of CYP1A2 protein20183062
C024273profenofosprofenofos results in increased expression of CYP1A2 mRNA22310298
C011088propachlorpropachlor results in increased activity of CYP1A2 protein10813365
C045950propiconazolepropiconazole results in increased expression of CYP1A2 protein7986207
C045950propiconazolepropiconazole results in increased expression of CYP1A2 mRNA19409404
C045950propiconazolepropiconazole results in increased expression of CYP1A2 mRNA16730040|1901034
C045950propiconazolepropiconazole results in increased activity of CYP1A2 protein3190755
C045950propiconazolepropiconazole results in increased expression of CYP1A2 mRNA15603923|1664397
C045950propiconazolepropiconazole results in increased expression of CYP1A2 protein7986207
D011433PropranololCYP1A2 protein affects the metabolism of Propranolol15286053
D011433PropranololPropranolol results in increased expression of CYP1A2 protein15618653
D011433PropranololPropranolol inhibits the reaction [Clenbuterol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]15710352
D011433PropranololPropranolol inhibits the reaction [Isoproterenol inhibits the reaction [Lipopolysaccharides results in decreased activity of CYP1A2 protein]]15710352
C006068propylparabenpropylparaben results in decreased activity of CYP1A2 protein27432241
C009091protocatechuic acidprotocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]15302093
D054328Proton Pump InhibitorsProton Pump Inhibitors results in increased expression of CYP1A2 mRNA25626140
C009093protopineprotopine results in increased expression of CYP1A2 mRNA21419197
C107773pterostilbenepterostilbene results in decreased activity of CYP1A2 protein16684708
C511975purpurinpurpurin results in decreased activity of CYP1A2 protein12379470
C511975purpurinpurpurin results in increased activity of CYP1A2 protein12744663
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17959153
C432165pyrazolanthronepyrazolanthrone results in increased expression of CYP1A2 mRNA17959153
C432165pyrazolanthroneresveratrol inhibits the reaction [pyrazolanthrone results in increased expression of CYP1A2 mRNA]17959153
C030984pyreneCYP1A2 protein results in increased hydroxylation of pyrene15016593
C030984pyrene[fluoranthene co-treated with pyrene co-treated with benz(a)anthracene co-treated with chrysene co-treated with benzo(b)fluoranthene co-treated with benzo(k)fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1A2 mRNA7750161
C030984pyrenepyrene results in increased expression of and results in increased activity of CYP1A2 protein17618724
C030984pyrenepyrene results in increased expression of CYP1A2 mRNA17618724|2616011
C030984pyrenepyrene results in increased expression of CYP1A2 protein26160115
C030984pyrenepyrene results in decreased activity of CYP1A2 protein19563207
C023666pyridinepyridine results in increased activity of CYP1A2 protein10413312|1046338
C023666pyridinepyridine results in increased expression of CYP1A2 mRNA10463385|1857340
C023666pyridinepyridine results in increased expression of CYP1A2 protein10413312|1046338
C021079pyridoxal isonicotinoyl hydrazone[pyridoxal isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A2 protein15588138
C021079pyridoxal isonicotinoyl hydrazone[pyridoxal isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A2 protein15588138
C021079pyridoxal isonicotinoyl hydrazonepyridoxal isonicotinoyl hydrazone results in decreased activity of CYP1A2 protein15588138
D011748PyrogallolPyrogallol results in increased activity of CYP1A2 protein18789925
D011748PyrogallolPyrogallol results in increased expression of CYP1A2 mRNA18789925
D011748Pyrogallolresveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP1A2 protein]18789925
D011748Pyrogallolresveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP1A2 mRNA]18789925
D011759PyrrolidinesCYP1A2 protein affects the metabolism of Pyrrolidines21053377
D011763Pyrrolizidine AlkaloidsPyrrolizidine Alkaloids results in increased expression of CYP1A2 mRNA26100227
D011794QuercetinQuercetin affects the activity of CYP1A2 protein21053930
D011794QuercetinQuercetin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21256954
D011794QuercetinQuercetin inhibits the reaction [beta-apo-8'-carotenal promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]16970932
D011794QuercetinQuercetin inhibits the reaction [beta-apo-8'-carotenal results in increased expression of CYP1A2 protein]16970932
D011794QuercetinQuercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]]16970932
D011794Quercetin"Quercetin inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]"16544949
D011794QuercetinQuercetin inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D011794QuercetinQuercetin promotes the reaction [JUND protein binds to CYP1A2 enhancer]10620351
D011794QuercetinQuercetin promotes the reaction [JUN protein binds to CYP1A2 enhancer]10620351
D011794QuercetinQuercetin results in decreased activity of CYP1A2 protein12949046|1591643
D011794QuercetinQuercetin results in increased expression of CYP1A2 mRNA19034627|2125695
D011794Quercetin"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A2 protein]"22044346
D011794QuercetinQuercetin results in decreased activity of CYP1A2 protein18420780
D011794Quercetin"Quercetin inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3-methylimidazo(4,5-f)quinoline]"11752233
D011794QuercetinQuercetin results in increased expression of and results in increased activity of CYP1A2 protein18421621
D011794QuercetinQuercetin results in increased expression of CYP1A2 mRNA18421621
D011802QuinidineQuinidine affects the reaction [CYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide]19053182
D011802QuinidineQuinidine results in decreased activity of CYP1A2 protein15916432
D011803QuinineQuinine results in increased expression of CYP1A2 mRNA12451431
C037219quinolinequinoline analog results in decreased activity of CYP1A2 protein15916432
D011806Quinolinium CompoundsQuinolinium Compounds results in increased expression of CYP1A2 mRNA23000282
D064750RabeprazoleRabeprazole results in increased expression of CYP1A2 mRNA12623754
D064750RabeprazoleRabeprazole results in increased expression of CYP1A2 mRNA25626140
C495910ramelteonCYP1A2 protein results in increased metabolism of ramelteon17069551
D017382Reactive Oxygen Species[[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] which results in increased abundance of Reactive Oxygen Species20118626
D012110ReserpineReserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D012110ReserpineReserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
D012110Reserpine[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]16510159
D012110Reserpine[Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]16510159
C059514resveratrolCYP1A2 protein affects the metabolism of resveratrol15276085
C059514resveratrolImipramine inhibits the reaction [resveratrol results in decreased activity of CYP1A2 protein]11714871
C059514resveratrolNADP promotes the reaction [resveratrol results in decreased activity of CYP1A2 protein]11714871
C059514resveratrol"resveratrol inhibits the reaction [15,16-dihydrotanshinone I results in increased expression of CYP1A2 mRNA]"21262253
C059514resveratrolresveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]10496959
C059514resveratrolresveratrol inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA]21262253
C059514resveratrol"resveratrol inhibits the reaction [CYP1A2 protein results in increased oxidation of 3,3'-diindolylmethane]"16544949
C059514resveratrolresveratrol inhibits the reaction [pyrazolanthrone results in increased expression of CYP1A2 mRNA]17959153
C059514resveratrolresveratrol inhibits the reaction [tanshinone results in increased expression of CYP1A2 mRNA]21262253
C059514resveratrolresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19376845|2920974
C059514resveratrolresveratrol promotes the reaction [CYP1A2 protein results in increased metabolism of Caffeine]20716633
C059514resveratrolresveratrol results in decreased activity of CYP1A2 protein11714871
C059514resveratrolresveratrol analog results in decreased activity of CYP1A2 protein16684708
C059514resveratrolresveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]26204831
C059514resveratrolresveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]26204831
C059514resveratrolresveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP1A2 protein]18789925
C059514resveratrolresveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP1A2 mRNA]18789925
C059514resveratrolresveratrol results in decreased activity of CYP1A2 protein18420780|2595647
C059514resveratrol[resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA25905778
C059514resveratrolresveratrol results in decreased expression of CYP1A2 mRNA25905778
C003300retrorsineretrorsine results in increased expression of CYP1A224799337
C020491rheinrhein results in decreased activity of CYP1A2 protein27633141
D012293RifampinRifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D012293RifampinRifampin results in increased expression of CYP1A2 mRNA15977188
D012293RifampinRifampin results in increased expression of CYP1A2 protein15977188|1759030
D012293Rifampin[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA29162470
D012293Rifampin[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein25835148
D012293RifampinRifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D019438RitonavirRitonavir results in increased expression of CYP1A2 mRNA11918509
D019438RitonavirRitonavir results in decreased expression of CYP1A2 mRNA17719200
C116926rofecoxibrofecoxib inhibits the reaction [CYP1A2 protein results in increased metabolism of Caffeine]16934051
C116926rofecoxibrofecoxib inhibits the reaction [CYP1A2 protein results in increased metabolism of tizanidine]15834531|1693405
C116926rofecoxibrofecoxib results in decreased activity of CYP1A2 protein18816299
C116926rofecoxibrofecoxib results in decreased activity of CYP1A2 protein15834531
C089730rosiglitazonerosiglitazone results in increased expression of CYP1A2 mRNA25572481|2559613
C089730rosiglitazonerosiglitazone results in decreased expression of CYP1A2 mRNA25596134
C028632rutecarpinerutecarpine analog binds to and results in decreased activity of CYP1A2 protein12852960
C028632rutecarpinerutecarpine binds to and results in decreased activity of CYP1A2 protein12852960
C028632rutecarpinerutecarpine promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]15720787
C028632rutecarpinerutecarpine results in increased activity of CYP1A2 protein15720787
D012451SafroleSafrole results in decreased activity of CYP1A2 protein15778010
D012451SafroleSafrole results in increased expression of CYP1A2 mRNA8722114
C413684salicylaldehyde isonicotinoyl hydrazone[salicylaldehyde isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A2 protein15588138
C413684salicylaldehyde isonicotinoyl hydrazone[salicylaldehyde isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A2 protein15588138
C413684salicylaldehyde isonicotinoyl hydrazonesalicylaldehyde isonicotinoyl hydrazone results in decreased activity of CYP1A2 protein15588138
C031060salicylamidesalicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]14729655
D012503SaponinsSaponins results in decreased expression of CYP1A2 mRNA26590097
C515233saracatinibCYP1A2 protein results in increased oxidation of saracatinib27769111
C034557schizandrer Aschizandrer A results in decreased activity of CYP1A2 protein25753323
C034734schizandrin Aschizandrin A results in decreased activity of CYP1A2 protein25753323
C031409schizandrin Cschizandrin C results in decreased activity of CYP1A2 protein25753323
C033585schizandrol Bschizandrol B results in decreased activity of CYP1A2 protein25753323
C458179scutellareinCYP1A2 protein affects the metabolism of scutellarein19666078
D012631SecobarbitalSecobarbital results in increased expression of CYP1A2 mRNA10064569
D012642SelegilineCYP1A2 protein affects the metabolism of Selegiline16198659
D012643Selenium[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]21424224
C009237senecioninesenecionine results in increased expression of CYP1A2 mRNA26100227
C100180sesamexsesamex results in increased expression of CYP1A2 mRNA8722114
C016101shikoninshikonin results in decreased activity of CYP1A2 protein28941798
C016101shikoninshikonin results in decreased activity of CYP1A2 protein28941798
C120148SIB 1893SIB 1893 results in decreased activity of CYP1A2 protein15193955
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CYP1A2 mRNA23806026
D012822Silicon DioxideSilicon Dioxide results in increased expression of CYP1A2 mRNA25351596
D012834SilverSilver results in increased expression of CYP1A2 mRNA20219766
D012838SilymarinSilymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D012838SilymarinSilymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]23159886
D012838SilymarinSilymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]23159886
D012838SilymarinSilymarin inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]23159886
D012839SimazineCYP1A2 protein results in decreased susceptibility to Simazine26771455
D012839SimazineSimazine results in increased activity of CYP1A2 protein9711812
D012839SimazineSimazine results in increased expression of CYP1A2 protein9711812
C059295sinensetinCYP1A2 protein results in increased metabolism of sinensetin19666078
D012906SmokeSmoke affects the reaction [CYP1A2 gene polymorphism affects the metabolism of Clozapine]16044115
D012906SmokeSmoke promotes the reaction [CYP1A2 protein results in increased metabolism of Clozapine]16044115
D012906SmokeSmoke results in increased activity of CYP1A2 protein16044115
C017947sodium arsenitesodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 mRNA]11162773
C017947sodium arsenitesodium arsenite inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1A2 protein]11162773
C017947sodium arsenitesodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]20188822
C017947sodium arsenitesodium arsenite results in decreased activity of CYP1A2 protein11162773
C017947sodium arsenitesodium arsenite results in decreased expression of CYP1A223052196
C017947sodium arsenitetin mesoporphyrin inhibits the reaction [sodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]20188822
C017947sodium arsenitesodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]22535251
C017947sodium arsenitesodium arsenite results in decreased expression of CYP1A2 mRNA17451858|2506574
C017947sodium arsenitesodium arsenite results in increased expression of CYP1A2 mRNA22535251
C016104sodium bichromate[Benzo(a)pyrene co-treated with sodium bichromate] results in decreased expression of CYP1A2 mRNA22613061
C028982sodium chromate(VI)CYP1A2 protein results in increased reduction of sodium chromate(VI)1903091
D012969Sodium FluorideSodium Fluoride results in decreased expression of CYP1A2 mRNA21340527
C001873sporidesminsporidesmin affects the expression of CYP1A2 mRNA28193462
C075117squalestatin 1squalestatin 1 results in increased expression of CYP1A2 mRNA27225895
C075117squalestatin 1squalestatin 1 results in increased expression of CYP1A2 mRNA27225895
C523402SR 13668SR 13668 results in increased expression of CYP1A2 mRNA19135037
C539817S-sulindac"S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A2 mRNA]"19276279
C539817S-sulindacS-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19276279
C539817S-sulindacS-sulindac results in decreased activity of CYP1A2 protein19276279
D013241SterigmatocystinCYP1A2 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin20929267
D013241Sterigmatocystin[CYP1A2 protein results in increased glutathionylation of and results in increased hydroxylation of Sterigmatocystin] which results in increased chemical synthesis of Sterigmatocystin metabolite20929267
C012042steviolsteviol results in increased expression of CYP1A2 mRNA28887089
C012042steviolsteviol results in increased expression of CYP1A2 protein28887089
C012043steviosidestevioside results in increased expression of CYP1A2 mRNA28887089
C012043steviosidestevioside results in increased expression of CYP1A2 protein28887089
C021092stiripentolstiripentol results in decreased activity of CYP1A2 protein16022579
D013311StreptozocinStreptozocin results in decreased expression of CYP1A2 protein12700423
D013311Streptozocin[resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA25905778
D013311StreptozocinStreptozocin results in decreased expression of CYP1A2 mRNA25905778
D013311StreptozocinStreptozocin results in increased expression of CYP1A2 protein17442507
D013311Streptozocin[Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon17442507
D020058Styrenegadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP1A2 protein]18202523
D020058StyreneStyrene results in increased expression of CYP1A2 mRNA16418063|1820252
D020058StyreneStyrene results in increased expression of CYP1A2 protein16418063|1820252
C024075styrofoamstyrofoam analog affects the activity of CYP1A2 protein19909766
C024075styrofoamstyrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP1A2 protein]19909766
C033006sudan IIIsudan III results in increased expression of CYP1A2 protein20308224
D013426SulfaphenazoleSulfaphenazole results in decreased activity of CYP1A2 protein15916432
C016766sulforafan"sulforafan inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein]"19362136
C016766sulforafansulforafan inhibits the reaction [anthracene results in increased activity of CYP1A2 protein]19362136
C016766sulforafansulforafan inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]19202560
C016766sulforafansulforafan results in decreased expression of CYP1A2 mRNA20442190
C016766sulforafansulforafan results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein]22664424
C016766sulforafansulforafan results in increased expression of CYP1A2 protein15906351
D013458Sulfur DioxideSulfur Dioxide results in decreased activity of CYP1A2 protein16023800
D013458Sulfur DioxideSulfur Dioxide results in decreased expression of CYP1A2 mRNA16023800
D013467SulindacSulindac results in increased expression of CYP1A2 mRNA17985343
D013467SulindacSulindac results in decreased expression of CYP1A2 mRNA24136188
D013467SulindacSulindac results in increased expression of CYP1A2 mRNA16531450
C025462sulindac sulfidesulindac sulfide results in increased expression of CYP1A2 mRNA17985343
D013469SulpirideSulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]26466350
D013469SulpirideSulpiride results in decreased expression of CYP1A2 mRNA26466350
C473478sunitinibsunitinib results in increased expression of CYP1A2 mRNA26797788
D013491Suppressor Factors, Immunologic"Suppressor Factors, Immunologic results in increased expression of CYP1A2 mRNA"23000282
D013498SuraminSuramin results in decreased activity of CYP1A2 protein11124226
C446685systhanesysthane results in increased expression of CYP1A2 mRNA19409404
D014284TriiodothyronineTriiodothyronine affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]28478156
D014284TriiodothyronineTriiodothyronine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]28478156
D014284TriiodothyronineTriiodothyronine results in increased expression of CYP1A2 mRNA28478156
D013619TacrineTacrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013619TacrineCYP1A2 protein affects the metabolism of Tacrine15258105
D013619TacrineTacrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013619TacrineTacrine results in decreased activity of CYP1A2 protein15258105
C508967tamarixetintamarixetin results in increased expression of CYP1A2 mRNA19034627
D013629Tamoxifen[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Tamoxifen23397584
D013629TamoxifenCYP1A2 protein results in increased metabolism of Tamoxifen29285606
D013629Tamoxifen"[CYP1A2 protein results in increased metabolism of Tamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene"29285606
D013629TamoxifenTamoxifen metabolite results in increased activity of CYP1A2 protein29285606
D013629TamoxifenTamoxifen results in decreased activity of CYP1A2 protein18420780
D013629TamoxifenCYP1A2 protein results in increased hydroxylation of Tamoxifen15587933
C059006tangeretintangeretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17090139
C021751tanshinoneDactinomycin inhibits the reaction [tanshinone results in increased expression of CYP1A2 mRNA]21262253
C021751tanshinoneresveratrol inhibits the reaction [tanshinone results in increased expression of CYP1A2 mRNA]21262253
C021751tanshinonetanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]21262253
C021751tanshinonetanshinone promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]21262253
C021751tanshinonetanshinone results in increased expression of CYP1A2 mRNA21262253
C021751tanshinonetanshinone results in increased expression of CYP1A2 protein21262253
C516109tasquinimodtasquinimod analog results in increased expression of CYP1A2 mRNA28433708
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of CYP1A2 mRNA15885361
D013662TeaTea results in decreased expression of CYP1A2 mRNA19370779
D013662TeaTea results in decreased expression of CYP1A2 protein19370779
D013662TeaTea results in increased expression of and results in increased activity of CYP1A2 protein24815822
C087114tebuconazoleNR1I3 promotes the reaction [tebuconazole results in increased expression of CYP1A2 mRNA]25656644
C087114tebuconazoletebuconazole results in increased expression of CYP1A2 mRNA25656644
C105050tegaserodtegaserod results in decreased activity of CYP1A2 protein11560869
C010347terbutryneCYP1A2 protein results in increased metabolism of terbutryne8971136
C010347terbutrynePOR protein promotes the reaction [CYP1A2 protein results in increased metabolism of terbutryne]8971136
C501413tesaglitazartesaglitazar results in decreased expression of CYP1A2 mRNA21515302
D013749TetrachlorodibenzodioxinAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]15155550
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA15155550
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 protein15155550
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA26854739|8955152
D013749Tetrachlorodibenzodioxin1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxin"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"19276279
D013749Tetrachlorodibenzodioxin"2,3,3',4,4',5-hexachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749Tetrachlorodibenzodioxin"2,3,3',4,4'-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749Tetrachlorodibenzodioxin"2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749Tetrachlorodibenzodioxin"2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749Tetrachlorodibenzodioxin"2,7-dinitrofluorene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749Tetrachlorodibenzodioxin"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"17183067
D013749Tetrachlorodibenzodioxin"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"17183067
D013749Tetrachlorodibenzodioxin"3',4'-dimethoxyflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"28357125
D013749Tetrachlorodibenzodioxin4-nitroquinolone-1-oxide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinAHR protein polymorphism affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]27535091
D013749Tetrachlorodibenzodioxinalpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinAminoquinolines inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinAzacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]12927368
D013749TetrachlorodibenzodioxinBenzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinbeta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinChlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinCisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinClozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinCYP1A2 protein affects the susceptibility to Tetrachlorodibenzodioxin16636061
D013749TetrachlorodibenzodioxinDantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinDexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19022236
D013749TetrachlorodibenzodioxinDitiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinDoxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1A2 mRNA19619570
D013749Tetrachlorodibenzodioxinflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17090139
D013749Tetrachlorodibenzodioxinfurafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxingalangin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17090139
D013749TetrachlorodibenzodioxinHydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinisoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]25110319
D013749TetrachlorodibenzodioxinIsoproterenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMelphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMethotrexate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMethylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]19022236
D013749TetrachlorodibenzodioxinMycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]25929522
D013749TetrachlorodibenzodioxinN-(2-(3H-indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)purin-6-amine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]21493753
D013749TetrachlorodibenzodioxinNCX 4040 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19542225
D013749TetrachlorodibenzodioxinNitrofurantoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinPapaverine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinPerhexiline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinPlant Extracts inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]11064004
D013749Tetrachlorodibenzodioxinpyrazolanthrone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17959153
D013749Tetrachlorodibenzodioxinresveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19376845|2920974
D013749TetrachlorodibenzodioxinRifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinsalicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]14729655
D013749Tetrachlorodibenzodioxinsodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]20188822
D013749TetrachlorodibenzodioxinS-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]19276279
D013749TetrachlorodibenzodioxinTacrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxintangeretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17090139
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CYP1A2 mRNA22298810
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA14729655
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with AHR mRNA] affects the expression of CYP1A2 mRNA20619336
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA29162470
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A2 enhancer]17785579
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased activity of CYP1A2 protein15659567
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of CYP1A2 protein16426572|1718306
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein14709624|1642657
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA11064004|1136831
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 protein11370663|1625817
D013749Tetrachlorodibenzodioxintin mesoporphyrin inhibits the reaction [sodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]20188822
D013749Tetrachlorodibenzodioxintolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxintrichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]12927368
D013749TetrachlorodibenzodioxinTriiodothyronine affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]28478156
D013749TetrachlorodibenzodioxinTriiodothyronine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 protein]28478156
D013749TetrachlorodibenzodioxinVitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinAHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]16214954|2249639
D013749TetrachlorodibenzodioxinAHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP1A2 mRNA]15034205
D013749TetrachlorodibenzodioxinARNT affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]11043581|2093516
D013749TetrachlorodibenzodioxinCYP1A2 affects the susceptibility to Tetrachlorodibenzodioxin21095216
D013749TetrachlorodibenzodioxinCYP1A2 protein affects the abundance of and affects the susceptibility to Tetrachlorodibenzodioxin15003330
D013749TetrachlorodibenzodioxinCYP1A2 protein affects the abundance of Tetrachlorodibenzodioxin10448125|1969527
D013749Tetrachlorodibenzodioxin[CYP1A2 protein affects the abundance of Tetrachlorodibenzodioxin] inhibits the reaction [CYP1A1 protein results in increased metabolism of Tetrachlorodibenzodioxin]19695277
D013749TetrachlorodibenzodioxinCYP1A2 protein affects the susceptibility to Tetrachlorodibenzodioxin16636061
D013749TetrachlorodibenzodioxinIron-Dextran Complex inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]9443932
D013749TetrachlorodibenzodioxinMercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23231920
D013749TetrachlorodibenzodioxinMercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]22579925
D013749TetrachlorodibenzodioxinMercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]22579925
D013749Tetrachlorodibenzodioxinsodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]22535251
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CYP1A2 mRNA20819909|2637764
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of CYP1A2 mRNA"28433925
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with AHR protein] results in increased expression of CYP1A2 mRNA21534955
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of CYP1A2 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [Butyrates results in increased expression of CYP1A2 mRNA]15252868
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [trichostatin A results in increased expression of CYP1A2 mRNA]15252868
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A2 gene]28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A2 promoter]21889950
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CYP1A2 mRNA15034205
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA22496397
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of CYP1A2 protein10986007|1663606
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein23423713|2512931
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A215722456|2421300
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA11043581|1313028
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 protein17997381|2109521
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin results in increased localization of AHR protein] which results in increased expression of CYP1A2 mRNA8215422
D013749TetrachlorodibenzodioxinTetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]1313028
D013749TetrachlorodibenzodioxinVanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]23423713
D013749TetrachlorodibenzodioxinVanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23423713
D013749TetrachlorodibenzodioxinVanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]23423713
D013749TetrachlorodibenzodioxinVanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23423713
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA20153503
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 protein20153503
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A215993909
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA15664428
D013749Tetrachlorodibenzodioxin1-nitropyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxin"2,4-Dinitrophenol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749Tetrachlorodibenzodioxin"2,7-dinitrofluorene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]"18493746
D013749TetrachlorodibenzodioxinAcetaminophen inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinAHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23859880
D013749Tetrachlorodibenzodioxinalpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinAminoquinolines inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinarsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]22159698
D013749Tetrachlorodibenzodioxinarsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]22159698
D013749TetrachlorodibenzodioxinBenzo(a)pyrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinbeta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinCisplatin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinClozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinCYP1A2 protein binds to and affects the abundance of Tetrachlorodibenzodioxin16966094
D013749TetrachlorodibenzodioxinDexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]17690134
D013749TetrachlorodibenzodioxinDitiocarb inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinDoxorubicin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxin"Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]"16901605
D013749Tetrachlorodibenzodioxinellipticine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxinfurafylline inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinHemin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]22159698
D013749TetrachlorodibenzodioxinHydralazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinLevodopa inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMelphalan inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMethylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinMifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]]17690134
D013749TetrachlorodibenzodioxinOrphenadrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinRifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinTacrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CYP1A2 mRNA22298810
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,3,4,7,8-pentachlorodibenzofuran co-treated with 3,4,5,3',4'-pentachlorobiphenyl] results in increased activity of CYP1A2 protein"17342195
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin inhibits the reaction [CYP1A2 protein results in decreased methylation of 7-methoxyresorufin]12635099
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [CYP1A2 protein affects the metabolism of bromodichloromethane]12062927
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased activity of CYP1A2 protein15659567
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased activity of CYP1A2 protein12062927|1678109
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein11585058|2215969
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein] which results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline"11585058
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA10568693|1091096
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CYP1A2 protein12361703|1260615
D013749Tetrachlorodibenzodioxintin mesoporphyrin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]22159698
D013749Tetrachlorodibenzodioxintolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749TetrachlorodibenzodioxinVitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which binds to CYP1A2 enhancer9169078
D013750TetrachloroethyleneCYP1A2 protein results in increased metabolism of Tetrachloroethylene11684365
D013750TetrachloroethyleneTetrachloroethylene results in decreased expression of CYP1A2 mRNA28973375
C582340tetradecabromodiphenoxybenzenetetradecabromodiphenoxybenzene analog results in increased expression of CYP1A2 mRNA26854739
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]10620351
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer]10620351
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]10620351
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]1313028
C096277tetrahydrocurcumintetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1A2 mRNA]26102010
C018674tetrahydrofuranNR1I2 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA]28495613
C018674tetrahydrofuranNR1I3 protein affects the reaction [tetrahydrofuran results in increased expression of CYP1A2 mRNA]28495613
C018674tetrahydrofurantetrahydrofuran results in increased expression of CYP1A2 mRNA28495613
C014215tetrahydropalmatinetetrahydropalmatine results in decreased expression of CYP1A2 mRNA28257954
C014215tetrahydropalmatinetetrahydropalmatine results in decreased expression of CYP1A2 protein28257954
D013792ThalidomideThalidomide results in decreased expression of CYP1A2 mRNA28892372
D013805TheobromineCYP1A2 protein results in increased chemical synthesis of Theobromine1302044
D013805TheobromineCYP1A2 protein results in increased metabolism of Theobromine10215755
D013805Theobrominefurafylline affects the reaction [CYP1A2 protein results in increased metabolism of Theobromine]10215755
D013806TheophyllineCYP1A2 gene SNP affects the metabolism of Theophylline20797314
D013806TheophyllineCYP1A2 gene SNP affects the susceptibility to Theophylline12732846
D013806TheophyllineCYP1A2 promoter SNP affects the hydroxylation of Theophylline16841220
D013806TheophyllineCYP1A2 protein affects the metabolism of Theophylline12732846|1569282
D013806TheophyllineCYP1A2 protein results in increased chemical synthesis of Theophylline1302044
D013806TheophyllineCYP1A2 protein results in increased metabolism of Theophylline11483122|9701106
D013806TheophyllineFluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of Theophylline]9029748
D013806TheophyllineGriseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]9029748
D013806Theophylline[Ofloxacin co-treated with Clarithromycin] inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]11408986
D013806TheophyllineTheophylline results in decreased activity of CYP1A2 protein11465391
D013806Theophyllinezafirlukast inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]9701106
D013806TheophyllineCYP1A2 protein affects the metabolism of Theophylline15970798
D013806Theophyllineandrographolide affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline]20096675
D013806TheophyllineCYP1A2 protein affects the metabolism of Theophylline15720787|1598536
D013806TheophyllineCYP1A2 protein results in increased metabolism of Theophylline20096675
D013806TheophyllinePlant Extracts affects the reaction [CYP1A2 protein results in increased metabolism of Theophylline]20096675
D013806Theophyllinerutecarpine promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]15720787
D013806Theophylline[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Theophylline16556082
D013827Thiabendazolebeta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]10936227
D013827ThiabendazoleCYP1A2 protein affects the metabolism of Thiabendazole10936227|1292049
D013827ThiabendazoleThiabendazole results in decreased activity of CYP1A2 protein11124226|1626136
D013827ThiabendazoleThiabendazole results in increased expression of CYP1A2 mRNA18570159
D013827Thiabendazolebeta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]10936227
D013827ThiabendazoleCYP1A2 protein affects the metabolism of Thiabendazole10936227
D013827ThiabendazoleThiabendazole results in increased expression of CYP1A2 mRNA15110098|1853937
D013827ThiabendazoleThiabendazole results in increased expression of CYP1A2 protein15110098
C417209thiaclopridthiacloprid results in increased expression of CYP1A2 mRNA21784029
C417209thiaclopridthiacloprid results in increased expression of CYP1A2 protein21784029
D013853Thioacetamide[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP1A2 mRNA28943392
D013853ThioacetamideThioacetamide results in decreased expression of CYP1A2 mRNA23411599
D008063Thioctic AcidThioctic Acid inhibits the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D008063Thioctic Acid[CYP1A1 protein co-treated with CYP1A2 protein] affects the reaction [[Thioctic Acid results in decreased activity of POR protein] inhibits the reaction [aristolochic acid I results in increased abundance of [7-(deoxyadenosin-N(6)-yl)aristolactam I co-treated with 7-(deoxyguanosin-N(2)-yl)aristolactam I co-treated with 7-(deoxyadenosin-N(6)--yl)aristolactam II]]]21932800
D013875ThiophanateThiophanate results in increased expression of CYP1A2 protein10096430
D013881Thioridazine[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine23397584
D013881ThioridazineCYP1A2 protein results in increased metabolism of and results in increased activity of Thioridazine19482014
D013988TiclopidineCYP1A2 protein results in increased oxidation of and results in increased cleavage of Ticlopidine metabolite19170597
D013988TiclopidineTiclopidine inhibits the reaction [CYP1A2 protein results in increased oxidation of 4-amino-2-phenoxymethanesulfonanilide]19053182
D013988TiclopidineTiclopidine results in decreased activity of CYP1A2 protein10759690
C055421tin mesoporphyrintin mesoporphyrin inhibits the reaction [sodium arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]20188822
C055421tin mesoporphyrintin mesoporphyrin inhibits the reaction [arsenite inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]]22159698
C023754tizanidineCiprofloxacin inhibits the reaction [CYP1A2 protein affects the metabolism of tizanidine]15592331
C023754tizanidineCYP1A2 protein affects the metabolism of tizanidine15592331|1619865
C023754tizanidineCYP1A2 protein results in increased metabolism of tizanidine17618427
C023754tizanidine[[Ethinyl Estradiol co-treated with Gestodene] results in decreased activity of CYP1A2 protein] which results in decreased metabolism of tizanidine16198659
C023754tizanidinerofecoxib inhibits the reaction [CYP1A2 protein results in increased metabolism of tizanidine]15834531|1693405
C023754tizanidineCYP1A2 protein results in increased metabolism of tizanidine15834531
D014028Tobacco Smoke Pollution"3',4'-dimethoxyflavone affects the reaction [Tobacco Smoke Pollution analog results in increased expression of CYP1A2 mRNA]"28357125
D014028Tobacco Smoke PollutionCYP1A2 protein affects the susceptibility to Tobacco Smoke Pollution18499698
D014028Tobacco Smoke PollutionTobacco Smoke Pollution analog results in increased activity of CYP1A2 protein28357125
D014028Tobacco Smoke PollutionTobacco Smoke Pollution analog results in increased expression of CYP1A2 mRNA28357125
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased activity of CYP1A2 protein1913651
C024746tobacco tartobacco tar results in increased activity of CYP1A2 protein17089110
C066340tolcaponetolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C066340tolcaponetolcapone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
C066340tolcaponetolcapone results in increased expression of CYP1A2 mRNA24136188
C009500tolfenamic acidALB protein inhibits the reaction [tolfenamic acid results in decreased activity of CYP1A2 protein]17618427
C009500tolfenamic acidtolfenamic acid results in decreased activity of CYP1A2 protein17618427|1881629
D014050TolueneAcetone promotes the reaction [Toluene results in increased expression of CYP1A2 protein]8996725
D014050TolueneCYP1A2 protein results in increased oxidation of Toluene1994898
D014050TolueneMethylcholanthrene promotes the reaction [CYP1A2 protein results in increased oxidation of Toluene]1994898
D014050TolueneToluene results in increased expression of CYP1A2 protein8996725
D014112ToxapheneToxaphene results in increased expression of CYP1A2 mRNA26187448
C099150trabectedintrabectedin results in decreased expression of CYP1A2 mRNA12154027
C507866trans-1,2-dihydro-1,2-naphthalenediol"CYP1A2 protein results in increased abundance of trans-1,2-dihydro-1,2-naphthalenediol"16243959
C495469trans-3-(4'-hydroxyphenyl)-2-propenoic acidtrans-3-(4'-hydroxyphenyl)-2-propenoic acid results in decreased activity of CYP1A2 protein15841493
C542064trantinteroltrantinterol affects the activity of CYP1A2 protein21466844
D014191TranylcypromineTranylcypromine affects the reaction [[NADP co-treated with CYP1A2 protein co-treated with CYP2C8 protein co-treated with CYP2C9 protein co-treated with CYP2C19 protein co-treated with CYP2D6 protein co-treated with CYP3A4 protein co-treated with POR protein] results in increased metabolism of 1-(3-(4-phenoxyphenoxy)-2-oxopropyl)indole-5-carboxylic acid]24120545
D014191TranylcypromineTranylcypromine results in decreased activity of CYP1A2 protein15916432
D014212TretinoinTretinoin results in decreased expression of CYP1A2 mRNA16882163|7697808
D014212TretinoinTretinoin results in increased expression of CYP1A2 mRNA16985168
D014212TretinoinTretinoin results in decreased activity of CYP1A2 protein18420780
C032910triadimefontriadimefon results in increased expression of CYP1A2 mRNA20659493
D014223TriamtereneCYP1A2 protein results in increased hydroxylation of Triamterene16035375
D014227Triazinesalpha-naphthoflavone inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
D014227TriazinesCYP1A2 protein results in increased metabolism of Triazines9305587
D014227Triazinesfurafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
D014227TriazinesGestodene inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
D014227TriazinesKetoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]9305587
D014239Trichloroepoxypropane"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 1,2,5,6-dibenzanthracene"8961944
D014239Trichloroepoxypropane"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benz(a)anthracene8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of Benzo(a)pyrene8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of chrysene8961944
D014239Trichloroepoxypropane"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 1,2,5,6-dibenzanthracene"8961944
D014239Trichloroepoxypropane"[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benz(a)anthracene8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of Benzo(a)pyrene8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of benzo(c)phenanthrene8961944
D014239Trichloroepoxypropane[CYP1A2 protein co-treated with Trichloroepoxypropane] results in increased metabolism of chrysene8961944
D014241TrichloroethyleneTrichloroethylene results in increased expression of CYP1A2 mRNA19254012
C012589trichostatin Atrichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]12927368
C012589trichostatin Atrichostatin A results in increased expression of CYP1A2 mRNA12927368|2835712
C012589trichostatin ATetrachlorodibenzodioxin inhibits the reaction [trichostatin A results in increased expression of CYP1A2 mRNA]15252868
C012589trichostatin Atrichostatin A results in increased expression of CYP1A2 mRNA15252868
D014295TrimethoprimTrimethoprim results in decreased activity of CYP1A2 protein26599973
D014295Trimethoprim[Trimethoprim results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Amodiaquine26599973
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of CYP1A2 mRNA26144063
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of CYP1A2 protein26144063
C052920trimethylarsine oxidetrimethylarsine oxide results in increased expression of CYP1A2 mRNA17481689
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP1A2 protein18079364
D014315TriterpenesTriterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of CYP1A2 mRNA]18544911
C057693troglitazone[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to troglitazone23397584
D014363TryptaminesTryptamines analog results in decreased activity of CYP1A2 protein26599973
D014363Tryptamines[Tryptamines analog results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin26599973
C112106UAB 30UAB 30 results in increased expression of CYP1A2 mRNA19135037
C112106UAB 30UAB 30 analog results in decreased expression of CYP1A2 mRNA23292798
C112106UAB 30UAB 30 results in increased expression of CYP1A2 mRNA23292798
D014577UroporphyrinogensCYP1A2 protein affects the metabolism of Uroporphyrinogens9224771
D014577Uroporphyrinogens"2-amino-3,4-dimethylimidazo(4,5-f)quinoline inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]"1567206
D014577UroporphyrinogensCYP1A2 protein results in increased oxidation of Uroporphyrinogens1567206
D014577UroporphyrinogensKetoconazole inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]1567206
D014577UroporphyrinogensPhenacetin inhibits the reaction [CYP1A2 protein results in increased oxidation of Uroporphyrinogens]1567206
D014577UroporphyrinogensCYP1A2 protein results in increased oxidation of Uroporphyrinogens1617633
D014577Uroporphyrinogens[Methylcholanthrene results in increased activity of CYP1A2 protein] which results in increased oxidation of Uroporphyrinogens1617633
D014577UroporphyrinogensCYP1A2 protein affects the metabolism of Uroporphyrinogens9972481
C066668vadimezanAcridines analog inhibits the reaction [CYP1A2 protein results in increased oxidation of vadimezan]16120190
C066668vadimezanCYP1A2 protein results in increased oxidation of vadimezan16120190
C406224valdecoxibvaldecoxib results in increased expression of CYP1A2 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of CYP1A2 mRNA17292431
D014635Valproic AcidValproic Acid results in decreased expression of CYP1A2 mRNA17381134
D014639VanadiumVanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]23423713
D014639VanadiumVanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23423713
D014639VanadiumVanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1A2 protein]23423713
D014639VanadiumVanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA]23423713
D001335Vehicle EmissionsVehicle Emissions results in increased expression of CYP1A2 protein20435083
D001335Vehicle EmissionsVehicle Emissions results in increased expression of CYP1A2 mRNA22352393|2421647
C521013veliparibCYP1A2 protein results in increased metabolism of veliparib21436403
D014700VerapamilVerapamil results in decreased activity of CYP1A2 protein18420780
C025643vinclozolinvinclozolin results in increased expression of CYP1A2 protein7986207
C025643vinclozolin[fenarimol co-treated with vinclozolin] affects the expression of CYP1A2 protein17686559
C025643vinclozolin[fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP1A2 protein17686559
C025643vinclozolinvinclozolin results in increased expression of CYP1A2 protein7986207
C029297vinylidene chloridevinylidene chloride results in decreased expression of CYP1A2 protein10547960
D024483Vitamin K 3Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D024483Vitamin K 3Vitamin K 3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]18493746
D024483Vitamin K 3Vitamin K 3 results in increased activity of CYP1A2 protein15603920
D024483Vitamin K 3Vitamin K 3 results in increased expression of CYP1A2 mRNA15603920
C574123walrycin Awalrycin A results in increased expression of CYP1A2 mRNA22314385
D014859WarfarinCYP1A2 protein affects the metabolism of Warfarin14676821|1528051
D014859WarfarinCYP1A2 SNP affects the susceptibility to Warfarin28079798
C009687wortmanninwortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]26466350
C009687wortmanninwortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP1A2 mRNA]26466350
C104536xanthohumol"xanthohumol inhibits the reaction [2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1A2 mRNA]"22138251
C104536xanthohumolxanthohumol results in increased expression of CYP1A2 mRNA22138251
D015016Yohimbine[Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA28843594
C062735zafirlukastzafirlukast inhibits the reaction [CYP1A2 protein results in increased metabolism of Theophylline]9701106
C029659zearalenolCYP1A2 protein results in increased hydroxylation of zearalenol19931366
C029659zearalenol[CYP1A2 protein results in increased hydroxylation of zearalenol] which results in increased chemical synthesis of Catechols19931366
C063449zileutonzileuton inhibits the reaction [CYP1A2 protein results in increased metabolism of Phenacetin]14570767
C063449zileutonzileuton results in decreased activity of CYP1A2 protein14570767
D015032Zinc[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]21424224
C017803zinc protoporphyrin[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP1A2 protein26747958
C088658zoledronic acidzoledronic acid results in increased expression of CYP1A2 mRNA24714768|2559613
C089750zolmitriptanzolmitriptan results in decreased activity of CYP1A2 protein18816299
C049109zolpidemCYP1A2 protein results in increased metabolism of zolpidem16449812
D015049ZoxazolamineCYP1A2 protein results in increased metabolism of and results in decreased activity of Zoxazolamine16109766

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004497monooxygenase activity-IBA21873635  
GO:0004497monooxygenase activity-IDA15327587  19651758  
GO:0004497monooxygenase activity-TAS-  
GO:0005506iron ion binding-IEA-  
GO:0009055electron transfer activity-TAS2813353  
GO:0016491oxidoreductase activity-IDA16401082  19219744  
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-IMP2813353  
GO:0019899enzyme binding-IPI15680923  
GO:0020037heme binding-IDA17311915  
GO:0032451demethylase activity-IDA2813353  
GO:0034875caffeine oxidase activity-IDA18619574  
GO:0070330aromatase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006706steroid catabolic process-IMP18356043  
GO:0006778porphyrin-containing compound metabolic process-IEA-  
GO:0006805xenobiotic metabolic process-TAS-  
GO:0009403toxin biosynthetic process-IDA11511187  
GO:0009791post-embryonic development-IEA-  
GO:0009820alkaloid metabolic process-IDA11511187  
GO:0010468regulation of gene expression-IEA-  
GO:0016098monoterpenoid metabolic process-IDA16401082  
GO:0017144drug metabolic process-IDA15327587  19219744  
GO:0018894dibenzo-p-dioxin metabolic process-IEA-  
GO:0019373epoxygenase P450 pathway-TAS-  
GO:0022900electron transport chain-IEA-  
GO:0030324lung development-IEA-  
GO:0032259methylation-TAS-  
GO:0032355response to estradiol-IEA-  
GO:0032496response to lipopolysaccharide-IEA-  
GO:0032787monocarboxylic acid metabolic process-IDA19651758  
GO:0035902response to immobilization stress-IEA-  
GO:0042737drug catabolic process-IMP18356043  
GO:0042738exogenous drug catabolic process-IDA18619574  
GO:0042759long-chain fatty acid biosynthetic process-TAS-  
GO:0045333cellular respiration-IEA-  
GO:0046483heterocycle metabolic process-IDA15327587  
GO:0050665hydrogen peroxide biosynthetic process-IEA-  
GO:0055114oxidation-reduction process-IDA16401082  19219744  
GO:0070989oxidative demethylation-IDA18619574  
GO:0071276cellular response to cadmium ion-IEA-  
GO:0071280cellular response to copper ion-IEA-  
GO:0071615oxidative deethylation-IDA19029318  
GO:0097267omega-hydroxylase P450 pathway-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005789endoplasmic reticulum membrane-TAS-  
GO:0031090organelle membrane-IEA-  
GO:0043231intracellular membrane-bounded organelle-IBA21873635  
GO:0043231intracellular membrane-bounded organelle-IDA2813353  
KEGG ID KEGG Term
hsa00232Caffeine metabolism
hsa00380Tryptophan metabolism
hsa00591Linoleic acid metabolism
hsa00830Retinol metabolism
hsa00980Metabolism of xenobiotics by cytochrome P450
hsa00982Drug metabolism - cytochrome P450
hsa01100Metabolic pathways
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-156580Phase II - Conjugation of compoundsTAS
R-HSA-156581MethylationTAS
R-HSA-211859Biological oxidationsTAS
R-HSA-211897Cytochrome P450 - arranged by substrate typeTAS
R-HSA-211945Phase I - Functionalization of compoundsTAS
R-HSA-211957Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2TAS
R-HSA-211981XenobioticsTAS
R-HSA-2142670Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)TAS
R-HSA-2142753Arachidonic acid metabolismTAS
R-HSA-2142816Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)TAS
R-HSA-5423646Aflatoxin activation and detoxificationTAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-8978868Fatty acid metabolismTAS
R-HSA-9018677Biosynthesis of DHA-derived SPMsTAS
R-HSA-9018678Biosynthesis of specialized proresolving mediators (SPMs)TAS
R-HSA-9018681Biosynthesis of protectinsTAS
R-HSA-9018682Biosynthesis of maresinsTAS
R-HSA-9027307Biosynthesis of maresin-like SPMsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18690546CYP1A2, CYP2D6, GSTM1, GSTP1, and GSTT1 gene polymorphisms in patients with bladder cancer in a Turkish population. (2009)Altayli EInt Urol Nephrol
10493258Human cytochrome P4501A2. (1999)Landi MTIARC Sci Publ
15883149The dosing of atypical antipsychotics. (2005 May-Jun)de Leon JPsychosomatics
11907488Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19). (2002 Mar)Christensen MClin Pharmacol Ther
12700399The effect of cigarette smoke exposure and ascorbic acid intake on gene expression of antioxidant enzymes and other related enzymes in the livers and lungs of Shionogi rats with osteogenic disorders. (2003 Jun)Ueta EToxicol Sci
26104035Evidence supporting the need for considering the effects of smoking on drug disposition and effectiveness in medication practices: a systematic narrative review. (2015 Aug)Sohn HSInt J Clin Pharmacol Ther
19490292A review of smoking cessation: potentially risky effects on prescribed medications. (2009 Jun)Schaffer SDJ Clin Nurs
17089110Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. (2006 Dec)Petersen MSEur J Clin Pharmacol
16406813Effect of urban traffic, individual habits, and genetic polymorphisms on background urinary 1-hydroxypyrene excretion. (2007 Jan)Cocco PAnn Epidemiol
26552516Measurement of human CYP1A2 induction by inhalation exposure to benzo(a)pyrene based on in vivo isotope breath method. (2016 Jan)Duan XEnviron Pollut
7530323Effect of cigarette smoke on the mutagenic activation of various carcinogens in hamster. (1995 Jan)Mori YMutat Res
8986194Effect of administered ethanol on protein kinase C in human platelets. (1996 Dec)Deitrich RAAlcohol Clin Exp Res
26046844Effect of Cytochrome b5 Content on the Activity of Polymorphic CYP1A2, 2B6, and 2E1 in Human Liver Microsomes. (2015)Zhang HPLoS One
10741629Effect of age and smoking on in vivo CYP1A2, flavin-containing monooxygenase, and xanthine oxidase activities in Koreans: determination by caffeine metabolism. (2000 Mar)Chung WGClin Pharmacol Ther
15824912Influence of cigarette smoking on melatonin levels in man. (2005 May)Ursing CEur J Clin Pharmacol
9884318Heterogeneity in systemic availability of ondansetron and granisetron following oral administration. (1999 Jan)Corrigan BWDrug Metab Dispos
15073045Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans. (2004 Sep)Walters DGCarcinogenesis
22246422Influence of cytochrome P450 oxidoreductase genetic polymorphisms on CYP1A2 activity and inducibility by smoking. (2012 Feb)Dobrinas MPharmacogenet Genomics
17955229Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine. (2008 Jan)Backman JTEur J Clin Pharmacol
18687246The association of cigarette smoking with enhanced platelet inhibition by clopidogrel. (2008 Aug 12)Bliden KPJ Am Coll Cardiol
17603900Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. (2007 Jun 30)Fan CBMC Cancer
19088049Effect of cigarette smoking on imatinib in patients in the soft tissue and bone sarcoma group of the EORTC. (2008 Dec 15)van Erp NClin Cancer Res
29072170Caffeine intake and abstract reasoning among 1374 unselected men and women from general population. Role of the -163C>A polymorphism of CYP1A2 gene. (2017 Aug)Casiglia EClin Nutr ESPEN
23530639High coffee intake, but not caffeine, is associated with reduced estrogen receptor negative and postmenopausal breast cancer risk with no effect modification by CYP1A2 genotype. (2013)Lowcock ECNutr Cancer
10589372Clinical pharmacokinetics of mexiletine. (1999 Nov)Labbe LClin Pharmacokinet
18499698Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. (2008 Jun)Suzuki HCarcinogenesis
26095139Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR. (2015)Toselli FXenobiotica
11704898[Olanzapine: pharmacology, pharmacokinetics and therapeutic drug monitoring]. (2001 Nov)Rao MLFortschr Neurol Psychiatr
21192135High correlation between serum and cerebrospinal fluid olanzapine concentrations in patients with schizophrenia or schizoaffective disorder medicating with oral olanzapine as the only antipsychotic drug. (2011 Feb)Skogh EJ Clin Psychopharmacol
24408517Simultaneous quantification of the abundance of several cytochrome P450 and uridine 5'-diphospho-glucuronosyltransferase enzymes in human liver microsomes using multiplexed targeted proteomics. (2014 Apr)Achour BDrug Metab Dispos
24668907Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk. (2014 Jun)Jenkins MMAm J Med Genet A
8214432Comparison of levels of cytochromes P-450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples. (1993 Aug)Lucas DAlcohol Clin Exp Res
20118554Effects of cigarette smoking and cytochrome P450 2D6 genotype on fluvoxamine concentration in plasma of Japanese patients. (2010)Katoh YBiol Pharm Bull
8706775Omeprazole and lansoprazole are not inducers of cytochrome P4501A2 under conventional therapeutic conditions. (1996)Rizzo NEur J Clin Pharmacol
9202749Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2. (1997 May 12)MacLeod SMutat Res
16184070Examining concentration-dependent toxicity of clozapine: role of therapeutic drug monitoring. (2005 Sep)Khan AYJ Psychiatr Pract
21797774Association of caffeine consumption and smoking status with the serum concentrations of polychlorinated biphenyls, dioxins, and furans in the general U.S. population: NHANES 2003-2004. (2011)Jain RBJ Toxicol Environ Health A
27894333Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and AHR, CYP1A1, CYP1A2, or CYP1B1 genotype. (2016 Nov 28)Jorge-Nebert LFHum Genomics
27067104Impact of dioxins on antipyrine metabolism in firefighters. (2016 May 27)Chernyak YIToxicol Lett
10353456A puzzling case of seizures and visual hallucinations during clomipramine treatment with a high dose but causing a low serum concentration. (1999 May)Terao TActa Psychiatr Scand
15095308Carotenoids/vitamin C and smoking-related bladder cancer. (2004 Jun 20)Castelao JEInt J Cancer
22628494Heterocyclic amine intake, smoking, cytochrome P450 1A2 and N-acetylation phenotypes, and risk of colorectal adenoma in a multiethnic population. (2013 Mar)Voutsinas JGut
7619675Metabolism of theophylline by cDNA-expressed human cytochromes P-450. (1995 Mar)Ha HRBr J Clin Pharmacol
12640212Role of the smoking-induced cytochrome P450 (CYP)1A2 and polymorphic CYP2D6 in steady-state concentration of olanzapine. (2003 Apr)Carrillo JAJ Clin Psychopharmacol
15505641Genetic susceptibility to tardive dyskinesia in chronic schizophrenia subjects: I. Association of CYP1A2 gene polymorphism. (2005)Tiwari AKPharmacogenomics J
15890241NAT2 fast acetylator genotype is associated with an increased risk of lung cancer among never-smoking women in Taiwan. (2005 Jun 1)Chiou HLCancer Lett
11817502Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizophrenia. (2002 Feb)Shimoda KProg Neuropsychopharmacol Biol Psychiatry
9472843The extent and determinants of changes in CYP2D6 and CYP1A2 activities with therapeutic doses of sertraline. (1998 Feb)Ozdemir VJ Clin Psychopharmacol
7920209Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene. (1994 Jul-Aug)Nakajima MCancer Epidemiol Biomarkers Prev
11532863Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man. (2001 Sep)Murray SCarcinogenesis
15663294CYP1A2 in a smoking and a non-smoking population; correlation of urinary and salivary phenotypic ratios. (2004)Woolridge HDrug Metabol Drug Interact
9443850Nicotine metabolism in liver microsomes from rats with acute hepatitis or cirrhosis. (1998 Jan)Nakajima MDrug Metab Dispos
19806921[Population pharmacokinetics research of clozapine in Chinese schizophrenic patients]. (2009 Jul)Qiu XWYao Xue Xue Bao
19643819Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japanese population. (2009 Oct)Imaizumi TCarcinogenesis
26856397Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3. (2016 Mar)Okubo MHum Psychopharmacol
29681089Genetic variation in biotransformation enzymes, air pollution exposures, and risk of spina bifida. (2018 May)Padula AMAm J Med Genet A
21095272Association between smoking, outcomes, and early clopidogrel use in patients with acute coronary syndrome: insights from the Global Registry of Acute Coronary Events. (2010 Nov)Sibbald MAm Heart J
27203225Cigarette smoking has a differential effect on the plasma level of clozapine in Taiwanese schizophrenic patients associated with the CYP1A2 gene -163A/C single nucleotide polymorphism. (2016 Aug)Huang HCPsychiatr Genet
20966044Cigarette smoke extract induces CYP2B6 through constitutive androstane receptor in hepatocytes. (2011 Jan)Washio IDrug Metab Dispos
24170642Clinically significant drug interactions with atypical antipsychotics. (2013 Dec)Kennedy WKCNS Drugs
9390106Impact of long-term ethanol consumption on CYP1A2 activity. (1997 Nov)Rizzo NClin Pharmacol Ther
21490707Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption. (2011 Apr)Cornelis MCPLoS Genet
29734455Response to Agomelatine Treatment is Independent of Smoking Status and Dosage: Results From the AGOPSYCH Study. (2018 May 7)Englisch SPharmacopsychiatry
17564586Caffeine intake and small-for-gestational-age birth: modifying effects of xenobiotic-metabolising genes and smoking. (2007 Jul)Infante-Rivard CPaediatr Perinat Epidemiol
27106177Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products. (2016 Nov)Anderson GDClin Pharmacokinet
29762875In Vivo Assessment of the Effect of CYP1A2 Inhibition and Induction on Pomalidomide Pharmacokinetics in Healthy Subjects. (2018 May 15)Li YJ Clin Pharmacol
7788860Expression of cytochrome P450 and microsomal epoxide hydrolase in cervical and oral epithelial cells immortalized by human papillomavirus type 16 E6/E7 genes. (1995 Jun)Farin FMCarcinogenesis
14659985Smoking impact on CYP1A2 activity in a group of patients with schizophrenia. (2004 Jan)Bozikas VPEur Neuropsychopharmacol
25218365Diversified expression of aryl hydrocarbon receptor dependent genes in human laryngeal squamous cell carcinoma cell lines treated with beta-naphthoflavone. (2014 Nov 18)Brauze DToxicol Lett
16901763Increased vascular contractility in isolated vessels from cigarette smoking rats is mediated by basal endothelin release. (2007 Jan)Rahman MMVascul Pharmacol
8895986Cytochrome P-450 and acetyltransferase expression as biomarkers of carcinogen-DNA adduct levels and human cancer susceptibility. (1996)Badawi AFProg Clin Biol Res
20957336CYP1A2*1F and GSTM1 alleles are associated with susceptibility to porphyria cutanea tarda. (2011 Mar-Apr)Wickliffe JKMol Med
22648710CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking. (2012 Jul)Rodenburg EMAm J Clin Nutr
14501029Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate. (2003)Nordskog BKCardiovasc Toxicol
10233204Dietary caffeine as a probe agent for assessment of cytochrome P4501A2 activity in random urine samples. (1999 Apr)Nordmark ABr J Clin Pharmacol
10427467Drug interactions with tobacco smoking. An update. (1999 Jun)Zevin SClin Pharmacokinet
11502731Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, by human cytochrome P450 enzymes. (2001 Sep)Cherstniakova SADrug Metab Dispos
25090963Blood pressure in relation to coffee and caffeine consumption. (2014 Sep)Guessous ICurr Hypertens Rep
1394840Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine. (1992 Sep)Vistisen KCarcinogenesis
12172216The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors. (2002 Aug)Rasmussen BBPharmacogenetics
15217502Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study. (2004)Hong CCBreast Cancer Res
7640151Imipramine metabolism in relation to the sparteine and mephenytoin oxidation polymorphisms--a population study. (1995 Apr)Madsen HBr J Clin Pharmacol
7720764A population and family study of CYP1A2 using caffeine urinary metabolites. (1995)Catteau AEur J Clin Pharmacol
21056942Environmental tobacco smoke in relation to bladder cancer risk--the Shanghai bladder cancer study [corrected]. (2010 Dec)Tao LCancer Epidemiol Biomarkers Prev
11751443Combined effects of well-done red meat, smoking, and rapid N-acetyltransferase 2 and CYP1A2 phenotypes in increasing colorectal cancer risk. (2001 Dec)Le Marchand LCancer Epidemiol Biomarkers Prev
15289794Time response of cytochrome P450 1A2 activity on cessation of heavy smoking. (2004 Aug)Faber MSClin Pharmacol Ther
11981356Tobacco and cannabis smoking cessation can lead to intoxication with clozapine or olanzapine. (2002 May)Zullino DFInt Clin Psychopharmacol
21593735Impact of smoking, smoking cessation, and genetic polymorphisms on CYP1A2 activity and inducibility. (2011 Jul)Dobrinas MClin Pharmacol Ther
26137357Genetic and Clinical Factors Affecting Plasma Clozapine Concentration. (2015)Olsson EPrim Care Companion CNS Disord
10098460Oxidative DNA damage in vivo: relationship to age, plasma antioxidants, drug metabolism, glutathione-S-transferase activity and urinary creatinine excretion. (1998 Dec)Poulsen HEFree Radic Res
11470995Plasma caffeine metabolite ratio (17X/137X) in vivo associated with G-2964A and C734A polymorphisms of human CYP1A2. (2001 Jul)Han XMPharmacogenetics
23602770The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study. (2013 Aug 6)Gurbel PAJ Am Coll Cardiol
22724322[Smoking and drug interactions]. (2012)Rouhos ADuodecim
22149257A pharmacokinetic-pharmacodynamic model for predicting the impact of CYP2C9 and VKORC1 polymorphisms on fluindione and acenocoumarol during induction therapy. (2012 Jan 1)Verstuyft CClin Pharmacokinet
15544431Cigarette smoking, metabolic activation and carcinogenesis. (2004 Oct)Nishikawa ACurr Drug Metab
15949157The cytochrome P450 CYP1A2 genetic polymorphisms *1F and *1D do not affect clozapine clearance in a group of schizophrenic patients. (2005 May)Kootstra-Ros JEAnn Clin Biochem
15917149Occupational exposure to polycyclic aromatic hydrocarbons in German industries: association between exogenous exposure and urinary metabolites and its modulation by enzyme polymorphisms. (2005 Jul 4)Rihs HPToxicol Lett
25288136Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. (2015 May)Cornelis MCMol Psychiatry
18157525Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes. (2008 Apr)Djordjevic NEur J Clin Pharmacol
17477782NAT2 and CYP1A2 polymorphisms and lung cancer risk in relation to smoking status. (2007 Jan-Mar)Osawa YAsian Pac J Cancer Prev
27783139Lack of effect of smoking status on axitinib pharmacokinetics in patients with non-small-cell lung cancer. (2016 Dec)Garrett MCancer Chemother Pharmacol
12663508Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2. (2003 Mar)Gago-Dominguez MCarcinogenesis
14586387Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. (2003 Nov)Benowitz NLClin Pharmacol Ther
22854411Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption. (2012 Sep)Josse ARAm J Clin Nutr
24177223Significant interactions between maternal PAH exposure and haplotypes in candidate genes on B[a]P-DNA adducts in a NYC cohort of non-smoking African-American and Dominican mothers and newborns. (2014 Jan)Iyer SCarcinogenesis
25851638Clinical assessment of drug-drug interactions of tasimelteon, a novel dual melatonin receptor agonist. (2015 Sep)Ogilvie BWJ Clin Pharmacol
11699614Olanzapine disposition in humans is unrelated to CYP1A2 and CYP2D6 phenotypes. (2001 Sep)Hagg SEur J Clin Pharmacol
10889552A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia. (2000 Jul)Basile VSMol Psychiatry
12351160Well-done red meat, metabolic phenotypes and colorectal cancer in Hawaii. (2002 Sep 30)Le Marchand LMutat Res
15013152Determination of urinary 13C-caffeine metabolites by liquid chromatography-mass spectrometry: the use of metabolic ratios to assess CYP1A2 activity. (2004 Feb 4)Caubet MSJ Pharm Biomed Anal
12790158Smoking and tardive dyskinesia: lack of involvement of the CYP1A2 gene. (2003 May)Chong SAJ Psychiatry Neurosci
18425847The novel N-substituted benztropine analog GA2-50 possesses pharmacokinetic and pharmacodynamic profiles favorable for a candidate substitute medication for cocaine abuse. (2008 Dec)Othman AAJ Pharm Sci
17221922In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios. (2007 Feb)Begas EBiomed Chromatogr
18798002Coffee consumption, genetic susceptibility and bladder cancer risk. (2009 Feb)Villanueva CMCancer Causes Control
11285205Cytochrome P4501A2 (CYP1A2) activity and lung cancer risk: a preliminary study among Chinese women in Singapore. (2001 Apr)Seow ACarcinogenesis
9517369Non-linear fluvoxamine disposition. (1998 Mar)Spigset OBr J Clin Pharmacol
26648056Common and Distinct Interactions of Chemical Inhibitors with Cytochrome P450 CYP1A2, CYP2A6 and CYP2B6 Enzymes. (2016)Raunio HDrug Metab Lett
15987714Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer. (2006 Jan)Li DCarcinogenesis
1306111Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. (1992 Jun)Butler MAPharmacogenetics
16203240Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. (2005 Oct)Ayotte PEnviron Health Perspect
21480221Cytochrome P4501A2 phenotype and bladder cancer risk: The Shanghai bladder cancer study. (2012 Mar 1)Tao LInt J Cancer
20547595CYP2D6 genotype and smoking influence fluvoxamine steady-state concentration in Japanese psychiatric patients: lessons for genotype-phenotype association study design in translational pharmacogenetics. (2011 Jul)Suzuki YJ Psychopharmacol
12214673Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. (2002 Aug)Kamataki TDrug Metab Rev
15448981Tobacco smoke-dependent changes in cytochrome P450 1A1, 1A2, and 2E1 protein expressions in fetuses, newborns, pregnant rats, and human placenta. (2005 Jan)Czekaj PArch Toxicol
1844873Human AH locus polymorphism and cancer: inducibility of CYP1A1 and other genes by combustion products and dioxin. (1991 Nov)Nebert DWPharmacogenetics
21053990Effect of intrinsic and extrinsic factors on the clinical pharmacokinetics and pharmacodynamics of prasugrel. (2010 Dec)Small DSClin Pharmacokinet
23776235Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. (2013 Jul 2)Iqbal JProc Natl Acad Sci U S A
27138278Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes. (2016)Rasmussen MKPLoS One
11189784[Biomarkers of gentotoxic risk and metabolic polymorphism]. (2000 Sep-Oct)Pavanello SMed Lav
21059812Effect of cigarette smoke on mutagenic activation of environmental carcinogens by cytochrome P450 2A8 and inactivation by glucuronidation in hamster liver. (2011 Mar)Tatematsu KMutagenesis
15327588A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study. (2004 Sep)Sharma ABr J Clin Pharmacol
29333880Pharmacogenetic analysis of opioid dependence treatment dose and dropout rate. (2018)Crist RCAm J Drug Alcohol Abuse
26200424[Switching to e-cigarettes affects drug concentration]. (2015)Berm EJNed Tijdschr Geneeskd
19961320Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. (2010 May)Zhou SFDrug Metab Rev
21254355Smoking, the xenobiotic pathway, and clubfoot. (2011 Jan)Sommer ABirth Defects Res A Clin Mol Teratol
21553932Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on 4-anilinoquinazolines. (2011 Jun)Scheffler MClin Pharmacokinet
10511917Olanzapine. Pharmacokinetic and pharmacodynamic profile. (1999 Sep)Callaghan JTClin Pharmacokinet
20143052Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure--an impact similar to male gender or smoking in schizophrenic patients. (2010 May)Ghotbi REur J Clin Pharmacol
9653923Analysis of urinary caffeine metabolites to assess biotransformation enzyme activities by reversed-phase high-performance liquid chromatography. (1998 May 8)Krul CJ Chromatogr B Biomed Sci Appl
29577422NOTCH4 is a possible novel susceptibility gene for dilated cardiomyopathy in the Chinese population: A case-control study. (2018 Mar 26)Shi XJ Clin Lab Anal
11012552Parkinson's disease and CYP1A2 activity. (2000 Oct)Forsyth JTBr J Clin Pharmacol
11207033Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects. (2001 Feb)Vaziri SAPharmacogenetics
10517990Effect of cigarette smoke on the mutagenic activation of environmental carcinogens by rodent liver. (1999 Jul 16)Koide AMutat Res
11059519Genetic polymorphism of enzymes involved in xenobiotic metabolism and the risk of colorectal cancer. (2000 Sep)Kiyohara CJ Epidemiol
18223460The relationship between the response of clinical symptoms and plasma olanzapine concentration, based on pharmacogenetics: Juntendo University Schizophrenia Projects (JUSP). (2008 Feb)Nozawa MTher Drug Monit
19193001Respiratory, cardiovascular and other physiological consequences of smoking cessation. (2009 Feb)Gratziou CCurr Med Res Opin
11353760Evaluation of methoxsalen, tranylcypromine, and tryptamine as specific and selective CYP2A6 inhibitors in vitro. (2001 Jun)Zhang WDrug Metab Dispos
11496364Lack of association between a functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene and tardive dyskinesia in schizophrenia. (2001 Aug 8)Schulze TGAm J Med Genet
10471069Detailed modelling of caffeine metabolism and examination of the CYP1A2 gene: lack of a polymorphism in CYP1A2 in Caucasians. (1999 Jun)Welfare MRPharmacogenetics
7786445CYP1A2 activity as a risk factor for bladder cancer. (1994 Dec)Lee SWJ Korean Med Sci
29514871Interindividual Differences in Caffeine Metabolism and Factors Driving Caffeine Consumption. (2018 Apr)Nehlig APharmacol Rev
24575657[Importance of drug interactions with smoking in modern drug research]. (2013)Laki SActa Pharm Hung
27565807Significant interactions between maternal PAH exposure and single nucleotide polymorphisms in candidate genes on B[ a ]P-DNA adducts in a cohort of non-smoking Polish mothers and newborns. (2016 Nov 1)Iyer SCarcinogenesis
11956673Effects of grapefruit juice and smoking on verapamil concentrations in steady state. (2002 Apr)Fuhr UEur J Clin Pharmacol
20859793Pharmacokinetics and metabolism of natural methylxanthines in animal and man. (2011)Arnaud MJHandb Exp Pharmacol
19071885Steady-state concentrations of mirtazapine, N-desmethylmirtazapine, 8-hydroxymirtazapine and their enantiomers in relation to cytochrome P450 2D6 genotype, age and smoking behaviour. (2009)Lind ABClin Pharmacokinet
22492992Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. (2012 Jul 15)Guessous IHum Mol Genet
10850389Effect of a genetic polymorphism of CYP1A2 inducibility on the steady state plasma concentrations of haloperidol and reduced haloperidol in Japanese patients with schizophrenia. (2000 Jun)Mihara KTher Drug Monit
12219983[13C]aminopyrine and [13C]caffeine breath test: influence of gender, cigarette smoking and oral contraceptives intake. (2002 Jun)Caubet MSIsotopes Environ Health Stud
18751408CYP1A2 164 A-->C polymorphism, cigarette smoking, consumption of well-done red meat and risk of developing colorectal adenomas and carcinomas. (2008 Jul-Aug)Saebo MAnticancer Res
27582327The Effect of Yokukansan, a Traditional Herbal Preparation Used for the Behavioral and Psychological Symptoms of Dementia, on the Drug-Metabolizing Enzyme Activities in Healthy Male Volunteers. (2016)Soraoka HBiol Pharm Bull
18159984Association of CYP1A1, CYP1A2, GSTM1 and NAT2 gene polymorphisms with colorectal cancer and smoking. (2007 Jul-Sep)Yoshida KAsian Pac J Cancer Prev
26626327The clinical potentials of adjunctive fluvoxamine to clozapine treatment: a systematic review. (2016 Mar)Polcwiartek CPsychopharmacology (Berl)
10224318Increased urinary excretion of 8-oxo-2'-deoxyguanosine, a biomarker of oxidative DNA damage, in urban bus drivers. (1999 Apr 26)Loft SMutat Res
23492909Pharmacogenetics of CYP1A2 activity and inducibility in smokers and exsmokers. (2013 May)Dobrinas MPharmacogenet Genomics
21081473Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. (2011 Feb)Wang HCarcinogenesis
11510628Clinical pharmacokinetics of quetiapine: an atypical antipsychotic. (2001)DeVane CLClin Pharmacokinet
11682234Analysis of urinary caffeine metabolites by HPLC-DAD: the use of metabolic ratios to assess CYP1A2 enzyme activity. (2002 Jan 1)Caubet MSJ Pharm Biomed Anal
10376760Estimation of cytochrome P-450 CYP1A2 activity in 863 healthy Caucasians using a saliva-based caffeine test. (1999 Apr)Tantcheva-Poor IPharmacogenetics
27993531Effect of smoking on risperidone pharmacokinetics - A multifactorial approach to better predict the influence on drug metabolism. (2017 Jul)Schoretsanitis GSchizophr Res
11791895The major fluvoxamine metabolite in urine is formed by CYP2D6. (2001 Nov)Spigset OEur J Clin Pharmacol
24260728CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics. (2013 Oct)Yim EYAsia Pac Allergy
12738191Induction of the procarcinogen-activating CYP1A2 by a herbal dietary supplement in rats and humans. (2003 Jun)Ryu SDFood Chem Toxicol
9110357Lifestyle and nutritional correlates of cytochrome CYP1A2 activity: inverse associations with plasma lutein and alpha-tocopherol. (1997 Feb)Le Marchand LPharmacogenetics
21148426Enhanced clopidogrel responsiveness in smokers: smokers' paradox is dependent on cytochrome P450 CYP1A2 status. (2011 Mar)Park KWArterioscler Thromb Vasc Biol
29101463A drug-drug interaction study to assess the effect of the CYP1A2 inhibitor fluvoxamine on the pharmacokinetics of dovitinib (TKI258) in patients with advanced solid tumors. (2018 Jan)de Weger VACancer Chemother Pharmacol
12618594The effect of smoking and cytochrome P450 CYP1A2 genetic polymorphism on clozapine clearance and dose requirement. (2003 Mar)van der Weide JPharmacogenetics
17370067Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans. (2007 Jun)Ghotbi REur J Clin Pharmacol
23167834Association between common CYP1A2 polymorphisms and theophylline metabolism in non-smoking healthy volunteers. (2013 Apr)Wang LBasic Clin Pharmacol Toxicol
12473741Effects of cigarette smoke and a heterocyclic amine, MeIQx on cytochrome P-450, mutagenic activation of various carcinogens and glucuronidation in rat liver. (2003 Jan)Mori YMutagenesis
25602162Cytochrome P450 1A2 co-determines neuroleptic load and may diminish tardive dyskinesia by increased inducibility. (2015 Apr)Ivanova SAWorld J Biol Psychiatry
12445029The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women. (2002 Nov)Nordmark ABr J Clin Pharmacol
22749033Role of CYP1A2 polymorphisms on lung cancer risk in a prospective study. (2012 Jun)Pavanello SCancer Genet
18784359Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population. (2008 Dec)Sun PCarcinogenesis
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