Gene info: ID 1545

Gene: CYP1B1

GENE ID: 1545

Synonyms: ASGD6|CP1B|CYPIB1|GLC3A|P4501B1

Description: cytochrome P450 family 1 subfamily B member 1

Gene type: protein-coding

Location: 2p22.2

dbXrefs: Ensembl:ENSG00000138061 MIM:601771 Vega:OTTHUMG00000100970 UniprotKB:Q16678

RefSeq: NG_008386.2

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND

# Publications: 107

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 8.573e-1 (AD) 8.273e-1 (ND)

DNA Methylation

Probe	Locus(GRCh37)	Gene	Region	p-val	Trait	PubMed ID
cg02162897	chr2:38300537	CYP1B1	Gene body	7.176e-4	Alcohol use disorders	26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
COL8A1	0.779
COL14A1	0.763
C7	0.761
FMOD	0.748
PLA2G4A	0.745
OGN	0.742
TGFBI	0.719
PTGER4	0.717
EDNRA	0.716
SLPI	0.712

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
HES6	-0.448
FEZF2	-0.43
HHATL	-0.424
ASPDH	-0.41
TTYH1	-0.36
NTSR2	-0.358
NEU4	-0.35
GPR37L1	-0.349
HAGHL	-0.349
CNTFR	-0.345

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB01645	Genistein	Small Molecule	446-72-0	Investigational	Target
DB02342	2-Methoxyestradiol	Small Molecule	362-07-2	Investigational	Target
DB03467	Naringenin	Small Molecule	480-41-1	Experimental	Target
DB04216	Quercetin	Small Molecule	117-39-5	Experimental\|Investigational	Target
DB06732	beta-Naphthoflavone	Small Molecule	6051-87-2	Experimental	Target
DB07776	Flavone	Small Molecule	525-82-6	Approved\|Experimental	Target
DB00121	Biotin	Small Molecule	58-85-5	Approved\|Investigational\|Nutraceutical	Enzyme
DB00201	Caffeine	Small Molecule	58-08-2	Approved	Enzyme
DB00277	Theophylline	Small Molecule	58-55-9	Approved	Enzyme
DB00338	Omeprazole	Small Molecule	73590-58-6	Approved\|Investigational	Enzyme
DB00363	Clozapine	Small Molecule	5786-21-0	Approved	Enzyme
DB00396	Progesterone	Small Molecule	57-83-0	Approved	Enzyme
DB00448	Lansoprazole	Small Molecule	103577-45-3	Approved\|Investigational	Enzyme
DB00499	Flutamide	Small Molecule	13311-84-7	Approved\|Investigational	Enzyme
DB00526	Oxaliplatin	Small Molecule	61825-94-3	Approved\|Investigational	Enzyme
DB00530	Erlotinib	Small Molecule	183321-74-6	Approved\|Investigational	Enzyme
DB00613	Amodiaquine	Small Molecule	86-42-0	Approved\|Investigational	Enzyme
DB00624	Testosterone	Small Molecule	58-22-0	Approved\|Investigational	Enzyme
DB00655	Estrone	Small Molecule	53-16-7	Approved	Enzyme
DB00675	Tamoxifen	Small Molecule	10540-29-1	Approved	Enzyme
DB00694	Daunorubicin	Small Molecule	20830-81-3	Approved	Enzyme
DB00783	Estradiol	Small Molecule	50-28-2	Approved\|Investigational	Enzyme
DB00818	Propofol	Small Molecule	2078-54-8	Approved\|Investigational	Enzyme
DB00997	Doxorubicin	Small Molecule	23214-92-8	Approved\|Investigational	Enzyme
DB01026	Ketoconazole	Small Molecule	65277-42-1	Approved\|Investigational	Enzyme
DB01065	Melatonin	Small Molecule	73-31-4	Approved\|Nutraceutical	Enzyme
DB01087	Primaquine	Small Molecule	90-34-6	Approved	Enzyme
DB01168	Procarbazine	Small Molecule	671-16-9	Approved\|Investigational	Enzyme
DB01169	Arsenic trioxide	Small Molecule	1327-53-3	Approved\|Investigational	Enzyme
DB01174	Phenobarbital	Small Molecule	50-06-6	Approved\|Investigational	Enzyme
DB01204	Mitoxantrone	Small Molecule	65271-80-9	Approved\|Investigational	Enzyme
DB01229	Paclitaxel	Small Molecule	33069-62-4	Approved	Enzyme
DB01234	Dexamethasone	Small Molecule	50-02-2	Approved\|Investigational	Enzyme
DB01248	Docetaxel	Small Molecule	114977-28-5	Approved\|Investigational	Enzyme
DB01254	Dasatinib	Small Molecule	302962-49-8	Approved\|Investigational	Enzyme
DB02709	Resveratrol	Small Molecule	501-36-0	Approved\|Experimental\|Investigational	Enzyme
DB09061	Cannabidiol	Small Molecule	13956-29-1	Approved\|Investigational	Enzyme
DB13943	Testosterone cypionate	Small Molecule	58-20-8	Approved	Enzyme
DB13944	Testosterone enanthate	Small Molecule	315-37-7	Approved	Enzyme
DB13946	Testosterone undecanoate	Small Molecule	5949-44-0	Approved\|Investigational	Enzyme
DB13952	Estradiol acetate	Small Molecule	4245-41-4	Approved\|Investigational	Enzyme
DB13953	Estradiol benzoate	Small Molecule	50-50-0	Approved\|Investigational	Enzyme
DB13954	Estradiol cypionate	Small Molecule	313-06-4	Approved\|Investigational	Enzyme
DB13955	Estradiol dienanthate	Small Molecule	7732-97-0	Approved\|Investigational	Enzyme
DB13956	Estradiol valerate	Small Molecule	979-32-8	Approved\|Investigational	Enzyme

ID	Drug Name	Action	PubMed
C006718	1,12-benzoperylene	"1,12-benzoperylene results in increased expression of CYP1B1 mRNA"	27196671
C006718	1,12-benzoperylene	"CYP1B1 protein results in increased oxidation of 1,12-benzoperylene"	23879290
C006718	1,12-benzoperylene	"[CYP1B1 protein results in increased oxidation of 1,12-benzoperylene] which results in increased abundance of 1,12-benzoperylene metabolite"	23879290
C561619	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	21383588
C561619	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	21383588
C034041	11-methylbenzanthracene	11-methylbenzanthracene results in increased expression of CYP1B1 mRNA	18205319
C402363	1-(1-propynyl)pyrene	1-(1-propynyl)pyrene binds to and results in decreased activity of CYP1B1 protein	19563207
C046839	1,2,3,4,6,7,8-heptachlorodibenzodioxin	"1,2,3,4,6,7,8-heptachlorodibenzodioxin results in increased expression of CYP1B1 mRNA"	25654323
C473650	1,2,3,4,6,7,8-heptachlorodibenzofuran	"1,2,3,4,6,7,8-heptachlorodibenzofuran analog results in increased expression of CYP1B1 mRNA"	25654323
C473650	1,2,3,4,6,7,8-heptachlorodibenzofuran	"1,2,3,4,6,7,8-heptachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	25654323
C051412	1,2,3,4,7,8-hexachlorodibenzofuran	"1,2,3,4,7,8-hexachlorodibenzofuran analog results in increased expression of CYP1B1 mRNA"	25654323
C051412	1,2,3,4,7,8-hexachlorodibenzofuran	"1,2,3,4,7,8-hexachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	25654323
C046838	1,2,3,6,7,8-hexachlorodibenzodioxin	"1,2,3,6,7,8-hexachlorodibenzodioxin results in increased expression of CYP1B1 mRNA"	25654323
C051452	1,2,3,7,8-pentachlorodibenzo-p-dioxin	"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased expression of CYP1B1 mRNA"	24472611
C051452	1,2,3,7,8-pentachlorodibenzo-p-dioxin	"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased expression of CYP1B1 mRNA"	23674508
C051452	1,2,3,7,8-pentachlorodibenzo-p-dioxin	"1,2,3,7,8-pentachlorodibenzo-p-dioxin results in increased expression of CYP1B1 mRNA"	25654323
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in increased expression of CYP1B1 mRNA"	11955671\|1725372
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in increased expression of CYP1B1 protein"	11955671
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in increased expression of CYP1B1 mRNA"	12117779\|2637769
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene affects the expression of CYP1B1 mRNA"	27099206
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]"	27099206
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in increased expression of CYP1B1 mRNA"	17961608
C021220	12-methylbenzanthracene	12-methylbenzanthracene results in increased expression of CYP1B1 mRNA	18205319
C576882	1-(2-trifluoromethoxyphenyl)-2-nitroethanone	1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in increased expression of CYP1B1 mRNA	25596134
C037413	1,3-dinitropyrene	"[CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 1,3-dinitropyrene"	11113705
C517215	13-hydroxyellipticine	CYP1B1 protein results in increased chemical synthesis of 13-hydroxyellipticine	22917556
C517943	1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone	"1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone results in increased expression of CYP1B1 mRNA"	26475489
C024023	1,4-dihydroxy-2-naphthoic acid	"[1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA"	27837168
C024023	1,4-dihydroxy-2-naphthoic acid	"[1,4-dihydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA"	27837168
C110414	1,4-dimethoxy-2-naphthoic acid	"[1,4-dimethoxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA"	27837168
C035342	1,4-naphthoquinone	"CYP1B1 protein results in increased abundance of 1,4-naphthoquinone"	16243959
C074153	1,4-phenylenebis(methylene)selenocyanate	"1,4-phenylenebis(methylene)selenocyanate binds to and results in decreased activity of CYP1B1 protein"	21732699
C033309	1,6-dinitropyrene	"1,6-dinitropyrene results in increased expression of CYP1B1 mRNA"	28186253
C002029	17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol	"[17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA"	17275934
C002029	17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol	"17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CYP1B1 mRNA"	17275934
C033310	1,8-dinitropyrene	"1,8-dinitropyrene results in increased expression of CYP1B1 mRNA"	21887816
C033310	1,8-dinitropyrene	"[CYP1B1 protein co-treated with POR protein] results in increased metabolism of 1,8-dinitropyrene"	11113705
C004482	1-aminopyrene	1-aminopyrene results in increased expression of CYP1B1 mRNA	12107646
C040345	1-chloropyrene	1-chloropyrene results in increased expression of CYP1B1 protein	19365803
C040345	1-chloropyrene	CYP1B1 protein results in increased metabolism of 1-chloropyrene	26252339
C042881	1-ethynylpyrene	1-ethynylpyrene binds to and results in decreased activity of CYP1B1 protein	19563207
C042881	1-ethynylpyrene	"1-ethynylpyrene inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10581206
C042881	1-ethynylpyrene	1-ethynylpyrene results in decreased activity of CYP1B1 protein	10581206
C042881	1-ethynylpyrene	1-ethynylpyrene results in increased expression of CYP1B1 mRNA	10581206
C042881	1-ethynylpyrene	AHR protein promotes the reaction [1-ethynylpyrene results in increased expression of CYP1B1 mRNA]	10581206
C042881	1-ethynylpyrene	Carbon Monoxide promotes the reaction [1-ethynylpyrene results in increased expression of CYP1B1 mRNA]	10581206
C042881	1-ethynylpyrene	1-ethynylpyrene results in decreased activity of CYP1B1 protein	7588239
C042881	1-ethynylpyrene	1-ethynylpyrene results in decreased activity of CYP1B1 protein	11922910
C050175	1-hydroxy-2-naphthoic acid	[1-hydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	27837168
C050175	1-hydroxy-2-naphthoic acid	[1-hydroxy-2-naphthoic acid binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	27837168
C051246	1-methylanthracene	[1-methylanthracene co-treated with fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	29170806
C051246	1-methylanthracene	[1-methylanthracene co-treated with fluoranthene] results in increased expression of CYP1B1 mRNA	28329830
C022032	1-methylbenz(a)anthracene	1-methylbenz(a)anthracene results in increased expression of CYP1B1 mRNA	18205319
C041507	1-methylphenanthrene	1-methylphenanthrene affects the expression of CYP1B1 mRNA	27099206
C041507	1-methylphenanthrene	1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]	27099206
C029350	1-naphthol	CYP1B1 protein results in increased abundance of 1-naphthol	16243959
C029350	1-naphthol	[1-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	27837168
C032668	1-nitropyrene	1-nitropyrene results in increased expression of CYP1B1 mRNA	21887816
C032668	1-nitropyrene	CYP1B1 protein results in increased metabolism of 1-nitropyrene	11525925
C032668	1-nitropyrene	1-nitropyrene results in increased expression of CYP1B1 mRNA	12117779
C024336	1-phenylazo-2-naphthol	CYP1B1 protein results in increased oxidation of 1-phenylazo-2-naphthol	17159775
C065011	1-vinylpyrene	1-vinylpyrene binds to and results in decreased activity of CYP1B1 protein	19563207
C548651	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CYP1B1 mRNA	28986273
C548651	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CYP1B1 mRNA	19933214
C029790	2,2',3',4,4',5-hexachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA"	15808785
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in decreased expression of CYP1B1 mRNA"	25565004
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of CYP1B1 mRNA"	19095052
C541980	2,2',4,6'-tetramethoxystilbene	"2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	19463925
C541980	2,2',4,6'-tetramethoxystilbene	"2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]"	19463925
C541980	2,2',4,6'-tetramethoxystilbene	"2,2',4,6'-tetramethoxystilbene results in decreased activity of CYP1B1 protein"	19463925
C541980	2,2',4,6'-tetramethoxystilbene	"[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,2',4,6'-tetramethoxystilbene"	19463925
C520611	2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester	"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	19276279
C520611	2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester	"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	19276279
C520611	2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester	"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester results in decreased activity of CYP1B1 protein"	19276279
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [AHR protein results in increased expression of CYP1B1 mRNA]	12758056
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9495809
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of CYP1B1 mRNA	19782052
C087667	2,3,3',4,4',5-hexachlorobiphenyl	"2,3,3',4,4',5-hexachlorobiphenyl results in increased expression of CYP1B1 mRNA"	23674508
C087667	2,3,3',4,4',5-hexachlorobiphenyl	"2,3,3',4,4',5-hexachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C067940	2,3,3',4,4'-pentachlorobiphenyl	"2,3,3',4,4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C070055	2,3',4,4',5-pentachlorobiphenyl	"2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	23674508
C070055	2,3',4,4',5-pentachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA"	15808785
C070055	2,3',4,4',5-pentachlorobiphenyl	"2,3',4,4',5-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C034559	2,3,4,5,3',4',5'-heptachlorobiphenyl	"2,3,4,5,3',4',5'-heptachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran promotes the reaction [AHR protein binds to CYP1B1 promoter]"	21703235
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran promotes the reaction [ARNT protein binds to CYP1B1 promoter]"	21703235
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran promotes the reaction [EP300 protein binds to CYP1B1 promoter]"	21703235
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]"	21703235
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	19358281\|2170323
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	23674508
C038890	2,3,4,7,8-pentachlorodibenzofuran	"2,3,4,7,8-pentachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	21724226\|2404627
C066841	2,3,7,8-tetrabromodibenzo-4-dioxin	"2,3,7,8-tetrabromodibenzo-4-dioxin results in increased expression of CYP1B1 mRNA"	19167471
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran promotes the reaction [AHR protein binds to CYP1B1 promoter]"	21703235
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran promotes the reaction [ARNT protein binds to CYP1B1 promoter]"	21703235
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran promotes the reaction [EP300 protein binds to CYP1B1 promoter]"	21703235
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]"	21703235
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	21703235
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP1B1 mRNA"	20951181\|2172422
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene binds to and results in decreased activity of CYP1B1 protein"	19563207
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene inhibits the reaction [CYP1B1 protein results in increased hydroxylation of Melatonin]"	15616152
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	16120791
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]"	16120791
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	21669939
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein"	15041469\|1561615
C440850	2,4,3',5'-tetramethoxystilbene	"alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene]"	16120791
C440850	2,4,3',5'-tetramethoxystilbene	"[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene"	16120791
C440850	2,4,3',5'-tetramethoxystilbene	"[2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein] which results in decreased activity of dibenzo(a,l)pyrene"	17961608
C440850	2,4,3',5'-tetramethoxystilbene	"[2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein] which results in decreased susceptibility to dibenzo(a,l)pyrene"	17961608
C440850	2,4,3',5'-tetramethoxystilbene	"2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein"	17961608\|2166993
C541132	2,4,4',5-tetrachlorobiphenyl	"2,4,4',5-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C081766	2,4,4'-trichlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA"	15808785
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl affects the expression of CYP1B1 mRNA"	20638727
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA"	15808785
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP1B1 mRNA"	20959002\|2565432
C009828	2,4,5,2',5'-pentachlorobiphenyl	"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA"	15808785
C038372	2,4,5,3',4',5'-hexachlorobiphenyl	"2,4,5,3',4',5'-hexachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C425784	2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole	2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYP1B1 mRNA	14707267\|1535588
C010914	2,4-diaminotoluene	"2,4-diaminotoluene results in increased expression of CYP1B1 mRNA"	20713471
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
C009407	2,5,2',5'-tetrachlorobiphenyl	"CYP1B1 protein affects the susceptibility to 2,5,2',5'-tetrachlorobiphenyl"	27913846
C021008	2',5'-dideoxyadenosine	"2',5'-dideoxyadenosine inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	22167199
C034889	2,6-dihydroxyanthraquinone	"2,6-dihydroxyanthraquinone results in increased expression of CYP1B1 mRNA"	11502733
C519626	2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline	"CYP1B1 protein results in increased oxidation of 2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline"	22118226
C077584	2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine	"[CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"	17279779
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1B1 mRNA"	20307560
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of CYP1B1 mRNA"	20702593
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased activity of CYP1B1 protein"	20307560
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CYP1B1 mRNA"	20307560\|2081688
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	17279779
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"[CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-amino-1-methyl-6-(4-hydroxyphenyl)imidazo(4,5-b)pyridine"	17279779
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"[CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	17279779
C036990	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	"[2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline] results in increased expression of CYP1B1 mRNA"	20307560
C036990	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in increased expression of CYP1B1 mRNA"	20307560\|2081688
C036990	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	"CYP1B1 protein affects the susceptibility to 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"	19223546
C109986	2-aminoethoxydiphenyl borate	2-aminoethoxydiphenyl borate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
C065012	2-ethynylnaphthalene	2-ethynylnaphthalene binds to and results in decreased activity of CYP1B1 protein	19563207
C535034	2-ethynylpyrene	2-ethynylpyrene binds to and results in decreased activity of CYP1B1 protein	19563207
C586542	2'-(glutathion-S-yl)-deschlorodiclofenac	[CYP1B1 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac	24246759
C060533	2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"[CYP1B1 protein results in increased metabolism of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine] which results in increased chemical synthesis of 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine"	17279779
C013031	2'-hydroxychalcone	"2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	15596260
C013031	2'-hydroxychalcone	2'-hydroxychalcone results in decreased activity of CYP1B1 protein	15596260
C001390	2-hydroxyestradiol	CYP1B1 protein affects the metabolism of [2-hydroxyestradiol co-treated with Glutathione]	14679015
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	"2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21513769
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]	28655636
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23625689
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]	26134484
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 mRNA]	28655636
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide results in decreased expression of CYP1B1 mRNA	23625689
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	24013123
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	26086121
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23196670
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]	21867498
C540395	2-methyl-5-isopropenylcyclohex-2-enone oxime	2-methyl-5-isopropenylcyclohex-2-enone oxime results in increased expression of CYP1B1 mRNA	19125687
C540395	2-methyl-5-isopropenylcyclohex-2-enone oxime	CYP1B1 protein results in increased metabolism of 2-methyl-5-isopropenylcyclohex-2-enone oxime	19125687
C047719	2-methylbenz(a)anthracene	2-methylbenz(a)anthracene results in increased expression of CYP1B1 mRNA	18205319
C028405	2-naphthol	[2-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	27837168
C049030	2-nitrofluoranthene	2-nitrofluoranthene results in increased expression of CYP1B1 mRNA	12107646
C049030	2-nitrofluoranthene	[CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 2-nitrofluoranthene	11113705
C026114	2-xylene	2-xylene results in decreased expression of CYP1B1 mRNA	20359517
C041525	3,3',4,5'-tetrahydroxystilbene	"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]"	20846786
C041525	3,3',4,5'-tetrahydroxystilbene	"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]]"	20846786
C041525	3,3',4,5'-tetrahydroxystilbene	"CYP1B1 protein affects the chemical synthesis of 3,3',4,5'-tetrahydroxystilbene"	15276085
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane analog results in increased expression of CYP1B1 mRNA"	11294972
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of CYP1B1 mRNA"	11294972
C520945	3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein]"	17183067
C520945	3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	17183067
C520945	3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]"	17183067
C520945	3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	17183067
C520945	3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide results in decreased activity of CYP1B1 protein"	17183067
C028451	3,4,3',4'-tetrachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA"	21803134\|2525115
C028451	3,4,3',4'-tetrachlorobiphenyl	"alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA"	12117779
C028451	3,4,3',4'-tetrachlorobiphenyl	"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of CYP1B1 mRNA"	15808785
C028451	3,4,3',4'-tetrachlorobiphenyl	"3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C027309	3,4,5,3',4',5'-hexachlorobiphenyl	"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of CYP1B1 mRNA"	15808785
C027309	3,4,5,3',4',5'-hexachlorobiphenyl	"3,4,5,3',4',5'-hexachlorobiphenyl results in increased expression of CYP1B1 mRNA"	25654323
C023035	3,4,5,3',4'-pentachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	21803134\|2525115
C023035	3,4,5,3',4'-pentachlorobiphenyl	"alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	17686920\|1961535
C023035	3,4,5,3',4'-pentachlorobiphenyl	"AHR2 protein affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	19615353
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	20471113
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	22164255
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	21354474
C023035	3,4,5,3',4'-pentachlorobiphenyl	"2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21513769
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl affects the expression of CYP1B1 mRNA"	21703328
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP1B1 mRNA"	22262711
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	15041469\|1935828
C023035	3,4,5,3',4'-pentachlorobiphenyl	"alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	22262711
C023035	3,4,5,3',4'-pentachlorobiphenyl	"Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21513769
C023035	3,4,5,3',4'-pentachlorobiphenyl	"fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21513769
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	24378064
C023035	3,4,5,3',4'-pentachlorobiphenyl	"Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	24378064
C023035	3,4,5,3',4'-pentachlorobiphenyl	"[3,4,3',4'-tetrachlorobiphenyl co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 3,4,5,3',4',5'-hexachlorobiphenyl] results in increased expression of CYP1B1 mRNA"	15808785
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA"	15908097\|1599013
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein"	15908097\|1599013
C023035	3,4,5,3',4'-pentachlorobiphenyl	"TNF protein promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 protein]"	17557910
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1"	20965207
C482492	3,4,5,4'-tetramethoxystilbene	"3,4,5,4'-tetramethoxystilbene results in decreased expression of CYP1B1 mRNA"	22687606
C482492	3,4,5,4'-tetramethoxystilbene	"3,4,5,4'-tetramethoxystilbene results in decreased expression of CYP1B1 protein"	22687606
C014464	3,4-dichloroaniline	"3,4-dichloroaniline results in increased expression of CYP1B1 mRNA"	24172598
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone binds to and results in decreased activity of CYP1B1 protein"	21053930
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]"	16484233
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	16530937\|1991960
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]"	16530937
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]"	22138065
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]"	22138065
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone inhibits the reaction [Plant Extracts results in increased expression of CYP1B1 mRNA]"	19794518
C509288	3',4'-dimethoxyflavone	"3',4'-dimethoxyflavone results in decreased expression of CYP1B1 mRNA"	17637178
C091547	3,7-dimethoxyflavone	"3,7-dimethoxyflavone results in decreased expression of CYP1B1 mRNA"	17637178
C057714	3-cyano-7-ethoxycoumarin	CYP1B1 protein affects the metabolism of 3-cyano-7-ethoxycoumarin	20599672
C041477	3-hydroxyflavone	3-hydroxyflavone binds to and results in decreased activity of CYP1B1 protein	21053930
C091768	3'-methoxy-4'-nitroflavone	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20823264
C091768	3'-methoxy-4'-nitroflavone	3'-methoxy-4'-nitroflavone inhibits the reaction [AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]]	15183014
C091768	3'-methoxy-4'-nitroflavone	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19782052
C091768	3'-methoxy-4'-nitroflavone	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	15050417\|2401312
C047368	3-methylquercetin	3-methylquercetin results in decreased expression of CYP1B1 mRNA	19794518
C033643	3-nitrofluoranthene	[CYP1B1 protein co-treated with POR protein] results in decreased metabolism of 3-nitrofluoranthene	11113705
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	25233930
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]	25233930
C583074	4,4'-hexafluorisopropylidene diphenol	"4,4'-hexafluorisopropylidene diphenol results in increased expression of CYP1B1 mRNA"	27567155
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C023626	4-ethynylbiphenyl	4-ethynylbiphenyl binds to and results in decreased activity of CYP1B1 protein	19563207
C535035	4-ethynylpyrene	4-ethynylpyrene binds to and results in decreased activity of CYP1B1 protein	19563207
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in decreased expression of CYP1B1 mRNA	12419474
C451019	4-hydroxychalcone	4-hydroxychalcone results in decreased activity of CYP1B1 protein	15596260
C014036	4-hydroxyestradiol	CYP1B1 gene polymorphism results in increased chemical synthesis of 4-hydroxyestradiol	18187806
C014036	4-hydroxyestradiol	CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol	15142886
C014036	4-hydroxyestradiol	CYP1B1 protein affects the metabolism of [4-hydroxyestradiol co-treated with Glutathione]	14679015
C014036	4-hydroxyestradiol	resveratrol inhibits the reaction [CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol]	15142886
C014036	4-hydroxyestradiol	CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol	15901486
C014036	4-hydroxyestradiol	CYP1B1 protein results in increased chemical synthesis of 4-hydroxyestradiol	18456490\|1849709
C026418	4-hydroxyestrone	[CYP1B1 protein results in increased hydroxylation of Estrone] which results in increased chemical synthesis of 4-hydroxyestrone	28985473
C026418	4-hydroxyestrone	[[CYP1B1 protein results in increased hydroxylation of Estrone] which results in increased chemical synthesis of 4-hydroxyestrone] which results in increased abundance of 4-hydroxyestrone-4-methyl ether	28985473
C035538	4-hydroxyestrone-4-methyl ether	[[CYP1B1 protein results in increased hydroxylation of Estrone] which results in increased chemical synthesis of 4-hydroxyestrone] which results in increased abundance of 4-hydroxyestrone-4-methyl ether	28985473
C045018	4-methoxyestradiol	CYP1B1 protein results in increased abundance of 4-methoxyestradiol	9706865
C045018	4-methoxyestradiol	Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]	9706865
C045018	4-methoxyestradiol	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]	9706865
C487850	4'-methoxyflavone	4'-methoxyflavone binds to and results in decreased activity of CYP1B1 protein	19563207\|2105393
C040143	4-methylbenz(a)anthracene	4-methylbenz(a)anthracene results in increased expression of CYP1B1 mRNA	18205319
C016583	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	CYP1B1 protein affects the metabolism of and results in increased activity of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	11774366
C016583	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1B1 mRNA]	20146248
C041594	4-nonylphenol	4-nonylphenol results in decreased expression of CYP1B1 mRNA	27087316\|2710977
C468646	5,12-naphthacenequinone	"5,12-naphthacenequinone results in increased expression of CYP1B1 mRNA"	17253728
C521334	5-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate	5-(4-dimethylaminobenzoyl)-aminovaleric acid hydroxamate affects the expression of CYP1B1 mRNA	20932894
C103112	5,7,4'-trimethylapigenin	"5,7,4'-trimethylapigenin results in decreased expression of CYP1B1 mRNA"	17637178
C060298	5,7-dimethoxyflavone	"5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]"	16484233
C060298	5,7-dimethoxyflavone	"5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	16530937
C060298	5,7-dimethoxyflavone	"5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]"	16530937
C060298	5,7-dimethoxyflavone	"5,7-dimethoxyflavone results in decreased activity of CYP1B1 protein"	15905203
C106219	5-androstene-16-fluoro-17-one	"5-androstene-16-fluoro-17-one inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	12097275
C106219	5-androstene-16-fluoro-17-one	5-androstene-16-fluoro-17-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12097275
C062711	5-hydroxyflavone	5-hydroxyflavone binds to and results in decreased activity of CYP1B1 protein	21053930
C487413	5-methoxyindole	5-methoxyindole results in decreased activity of CYP1B1 protein	18420780
C035724	5-methylbenzanthracene	5-methylbenzanthracene results in increased expression of CYP1B1 mRNA	18205319
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C454039	6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione	"6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1B1 mRNA"	11710520
C485383	6,7-dihydroxyflavone	"6,7-dihydroxyflavone binds to and results in decreased activity of CYP1B1 protein"	21053930
C100101	6-chrysenamine	6-chrysenamine results in increased expression of CYP1B1 mRNA	12117779
C111855	6-formylindolo(3,2-b)carbazole	"6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA"	19615353
C111855	6-formylindolo(3,2-b)carbazole	"AHR2 protein affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]"	19615353
C111855	6-formylindolo(3,2-b)carbazole	"6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1"	27697457
C111855	6-formylindolo(3,2-b)carbazole	"6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA"	27783115\|2914646
C111855	6-formylindolo(3,2-b)carbazole	"alpha-naphthoflavone inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]"	29146461
C111855	6-formylindolo(3,2-b)carbazole	"CL 075 promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]"	27783115
C111855	6-formylindolo(3,2-b)carbazole	"6-formylindolo(3,2-b)carbazole promotes the reaction [AHR protein results in increased expression of CYP1B1 mRNA]"	17020875
C111855	6-formylindolo(3,2-b)carbazole	"6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA"	17020875\|2770927
C111855	6-formylindolo(3,2-b)carbazole	"AHR protein affects the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]"	27709270
C057617	6-hydroxyluteolin	[CYP1B1 protein affects the metabolism of scutellarein] which results in increased chemical synthesis of 6-hydroxyluteolin	19666078
C057617	6-hydroxyluteolin	CYP1B1 protein results in increased chemical synthesis of 6-hydroxyluteolin	19666078
C053876	6-isopropoxy-9-oxoxanthene-2-carboxylic acid	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C053876	6-isopropoxy-9-oxoxanthene-2-carboxylic acid	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
C054923	6-methyl-1,3,8-trichlorodibenzofuran	"6-methyl-1,3,8-trichlorodibenzofuran results in increased expression of CYP1B1 mRNA"	19828881
C046305	6-methylbenz(a)anthracene	6-methylbenz(a)anthracene results in increased expression of CYP1B1 mRNA	18205319
C017503	6-methylbenzo(a)pyrene	6-methylbenzo(a)pyrene results in increased expression of CYP1B1 mRNA	21604763
C034699	6-nitrobenzo(a)pyrene	6-nitrobenzo(a)pyrene results in increased expression of CYP1B1 mRNA	12107646
C035986	6-nitrochrysene	6-nitrochrysene results in increased expression of CYP1B1 mRNA	12107646
C521871	6-prenylnaringenin	6-prenylnaringenin results in increased expression of CYP1B1 mRNA	27269377
C077646	7,12-benz(a)anthraquinone	"7,12-benz(a)anthraquinone results in increased expression of CYP1B1 mRNA"	23684558\|2614139
C077646	7,12-benz(a)anthraquinone	"AHR2 affects the reaction [7,12-benz(a)anthraquinone results in increased expression of CYP1B1 mRNA]"	26141390
C419147	7-benzyloxy-4-trifluoromethylcoumarin	CYP1B1 protein affects the metabolism of 7-benzyloxy-4-trifluoromethylcoumarin	20599672
C429845	7-hydroxyflavone	7-hydroxyflavone binds to and results in decreased activity of CYP1B1 protein	21053930
C076580	7-methoxyresorufin	CYP1B1 protein affects the metabolism of 7-methoxyresorufin	20599672
C021219	7-methylbenzanthracene	7-methylbenzanthracene results in increased expression of CYP1B1 mRNA	18205319
C031255	8-methylbenzanthracene	8-methylbenzanthracene results in increased expression of CYP1B1 mRNA	18205319
C006014	8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate	"8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	22167199
C421010	9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole	"CYP1B1 protein results in increased chemical synthesis of 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"	15279827
C096666	9-ethynylphenanthrene	9-ethynylphenanthrene binds to and results in decreased activity of CYP1B1 protein	19563207
C091375	9-phenanthrol	CYP1B1 protein results in increased abundance of 9-phenanthrol	27137136
C091375	9-phenanthrol	[CYP1B1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol	27137136
C023717	acacetin	acacetin binds to and results in decreased activity of CYP1B1 protein	21053930
C023717	acacetin	CYP1B1 protein results in increased metabolism of acacetin	21482471
C042552	acenaphthene	CYP1B1 protein results in increased oxidation of acenaphthene	25642975
C042552	acenaphthene	[CYP1B1 protein results in increased oxidation of acenaphthene] which results in increased chemical synthesis of acenaphthene-1-ol	25642975
C023723	acenaphthene-1-ol	[CYP1B1 protein results in increased oxidation of acenaphthene] which results in increased chemical synthesis of acenaphthene-1-ol	25642975
C042553	acenaphthylene	CYP1B1 protein results in increased oxidation of acenaphthylene	25642975
C042553	acenaphthylene	acenaphthylene results in increased expression of CYP1B1 mRNA	10402558
D000082	Acetaminophen	Acetaminophen affects the expression of CYP1B1 mRNA	25064622
D000082	Acetaminophen	Acetaminophen affects the expression of CYP1B1 mRNA	25458485
D000082	Acetaminophen	Acetaminophen results in decreased expression of CYP1B1 mRNA	26690555
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP1B1 mRNA	21420995\|2906747
D000082	Acetaminophen	CYP1B1 gene polymorphism affects the susceptibility to Acetaminophen	26104854
D000111	Acetylcysteine	Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]	21703343
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA]	22129741
C106812	adefovir dipivoxil	adefovir dipivoxil results in increased expression of CYP1B1 mRNA	25596134
D000242	Cyclic AMP	Cyclic AMP results in increased expression of CYP1B1 mRNA	12859982
D000242	Cyclic AMP	Cyclic AMP results in increased expression of CYP1B1 protein	12859982
D000242	Cyclic AMP	AHR protein promotes the reaction [Cyclic AMP results in increased expression of CYP1B1 mRNA]	12859982
D000242	Cyclic AMP	Cyclic AMP promotes the reaction [AHR protein binds to CYP1B1 enhancer]	12859982
D000242	Cyclic AMP	Cyclic AMP promotes the reaction [CREB1 protein binds to CYP1B1 enhancer]	12859982
D000242	Cyclic AMP	Cyclic AMP results in increased expression of CYP1B1 mRNA	12859982
C006418	adrenocorticotropin zinc	adrenocorticotropin zinc results in increased expression of CYP1B1 mRNA	19920212
C016601	afimoxifene	afimoxifene inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	19460354
C016601	afimoxifene	afimoxifene results in decreased activity of CYP1B1 protein	12419016
C016601	afimoxifene	afimoxifene results in increased expression of CYP1B1 mRNA	19901195
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of CYP1B1 protein	20106945
D016604	Aflatoxin B1	CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]	21907773
C412373	AG 1879	AG 1879 results in decreased expression of CYP1B1 mRNA	19782052
C046926	AH 23848	AH 23848 inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C046926	AH 23848	AH 23848 inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D000393	Air Pollutants	Air Pollutants results in increased expression of CYP1B1 mRNA	11955671\|1807949
D000393	Air Pollutants	Air Pollutants results in increased expression of CYP1B1 protein	11955671
D000393	Air Pollutants	Air Pollutants results in increased expression of CYP1B1 mRNA	18079490\|1836772
D000395	Air Pollutants, Occupational	"Air Pollutants, Occupational results in decreased expression of CYP1B1 mRNA"	19936710
C010078	alizarin	alizarin results in decreased activity of CYP1B1 protein	12379470
C038491	allyl sulfide	allyl sulfide results in increased expression of CYP1B1 mRNA	17129689
C038491	allyl sulfide	[Diethylstilbestrol co-treated with allyl sulfide] results in increased expression of CYP1B1 mRNA	17129689
C518327	aloe emodin	aloe emodin results in decreased activity of CYP1B1 protein	27633141
C011512	alpha-naphthoflavone	"alpha-naphthoflavone inhibits the reaction [3,4,3',4'-tetrachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C011512	alpha-naphthoflavone	"alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21803134
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19403181
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19403181
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in decreased expression of CYP1B1 mRNA	19403181
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in increased expression of CYP1B1 mRNA	19403181
C011512	alpha-naphthoflavone	alpha-naphthoflavone binds to and results in decreased activity of CYP1B1 protein	19563207\|2105393
C011512	alpha-naphthoflavone	"alpha-naphthoflavone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	22262711
C011512	alpha-naphthoflavone	"alpha-naphthoflavone inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]"	29146461
C011512	alpha-naphthoflavone	"alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene]"	16120791
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	15075337\|1918226
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in decreased activity of CYP1B1 protein	15280921
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in decreased expression of CYP1B1 mRNA	22262711
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in increased expression of CYP1B1 mRNA	22262711
C011512	alpha-naphthoflavone	CYP1B1 protein binds to alpha-naphthoflavone	27966929
C011512	alpha-naphthoflavone	CYP1B1 protein results in increased metabolism of alpha-naphthoflavone	16120791
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]	11577022
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]	27163632
C011164	amentoflavone	amentoflavone results in decreased activity of CYP1B1 protein	16271822
D000588	Amines	CYP1B1 protein affects the metabolism of Amines	15122594
C413760	aminoflavone	AHR mutant form inhibits the reaction [aminoflavone results in increased expression of CYP1B1 protein]	24885022
C413760	aminoflavone	AHR protein affects the reaction [aminoflavone results in increased expression of CYP1B1 mRNA]	24885022
C413760	aminoflavone	aminoflavone results in increased expression of CYP1B1 mRNA	24885022
C413760	aminoflavone	aminoflavone results in increased expression of CYP1B1 protein	24885022
D000638	Amiodarone	Amiodarone affects the expression of CYP1B1 mRNA	25064622
D000638	Amiodarone	CYP1B1 protein results in decreased susceptibility to Amiodarone	26477383
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of CYP1B1 mRNA	16483693
C030419	andrographolide	[andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1B1 mRNA	17825862
C030419	andrographolide	andrographolide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]	19737545
C023650	aniline	CYP1B1 protein affects the metabolism of [norharman co-treated with aniline]	15279827
C034020	anthracene	anthracene results in increased expression of CYP1B1 mRNA	21668866
D000880	Anthraquinones	Anthraquinones results in increased expression of CYP1B1 mRNA	11502733
D018501	Antirheumatic Agents	Antirheumatic Agents results in decreased expression of CYP1B1 mRNA	24449571
D047310	Apigenin	Apigenin binds to and results in decreased activity of CYP1B1 protein	21053930
D047310	Apigenin	Apigenin results in decreased activity of CYP1B1 protein	16271822\|2148247
D047310	Apigenin	CYP1B1 protein results in increased chemical synthesis of Apigenin	19666078
D047310	Apigenin	[CYP1B1 protein results in increased metabolism of genkwanin] which results in increased chemical synthesis of Apigenin	19666078
D047310	Apigenin	Apigenin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]	20930378
D016718	Arachidonic Acid	CYP1B1 protein affects the metabolism of Arachidonic Acid	15258110
D016718	Arachidonic Acid	CYP1B1 protein affects the metabolism of Arachidonic Acid	15258110
D016718	Arachidonic Acid	CYP1B1 protein results in increased metabolism of Arachidonic Acid	22230337
D001151	Arsenic	Arsenic affects the methylation of CYP1B1 gene	25304211
C006632	arsenic trioxide	arsenic trioxide affects the expression of CYP1B1 mRNA	17530438
C006632	arsenic trioxide	[Tretinoin co-treated with arsenic trioxide] results in decreased expression of CYP1B1 mRNA	15894607
C015001	arsenite	[arsenite co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	15894712
C015001	arsenite	arsenite results in decreased expression of CYP1B1 mRNA	15894712
D018053	Arsenites	Arsenites results in increased expression of CYP1B1 mRNA	22680237
D001280	Atrazine	Atrazine results in decreased expression of CYP1B1 mRNA	25929836
D001280	Atrazine	Atrazine results in increased expression of CYP1B1 mRNA	26891955
D001280	Atrazine	Atrazine results in increased expression of CYP1B1 mRNA	26775023
D001280	Atrazine	lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]	26775023
D001280	Atrazine	Atrazine inhibits the reaction [Chorionic Gonadotropin results in decreased expression of CYP1B1 mRNA]	26923738
D001280	Atrazine	Atrazine results in increased expression of CYP1B1 mRNA	26923738
D001374	Azacitidine	Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12927368
D001374	Azacitidine	Azacitidine results in increased expression of CYP1B1 mRNA	12927368\|2759006
C006680	baicalein	baicalein binds to and results in decreased activity of CYP1B1 protein	21053930
C006680	baicalein	baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	12224597
C006680	baicalein	baicalein results in decreased activity of CYP1B1 protein	21482471
C006680	baicalein	CYP1B1 protein results in increased chemical synthesis of baicalein	19666078
C006680	baicalein	[CYP1B1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein	19666078
C487081	belinostat	belinostat results in increased expression of CYP1B1 mRNA	26272509
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 mRNA	23656968
C030935	benz(a)anthracene	AHR protein affects the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	23396138
C030935	benz(a)anthracene	baicalein inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	12224597
C030935	benz(a)anthracene	[benz(a)anthracene co-treated with TNF protein] results in increased expression of CYP1B1 mRNA	23396138
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 mRNA	12224597\|1252007
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 protein	22236718
C030935	benz(a)anthracene	[andrographolide co-treated with benz(a)anthracene] results in increased expression of CYP1B1 mRNA	17825862
C030935	benz(a)anthracene	"benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446\|1049788
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 mRNA	10497882\|1211777
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 protein	10497882\|8022408
C030935	benz(a)anthracene	benz(a)anthracene results in increased stability of CYP1B1 protein	8022408
C030935	benz(a)anthracene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CYP1B1 mRNA	27858113
C030935	benz(a)anthracene	"Dehydroepiandrosterone inhibits the reaction [benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10497882
C030935	benz(a)anthracene	Dehydroepiandrosterone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	10497882
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 mRNA	18205319\|2138449
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP1B1 protein	8674863
C030935	benz(a)anthracene	[Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
C030935	benz(a)anthracene	Hydrocortisone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	8674863
C030935	benz(a)anthracene	Hydrocortisone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
C030935	benz(a)anthracene	Progesterone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
D001551	Benz(a)Anthracenes	Benz(a)Anthracenes results in increased expression of CYP1B1 mRNA	12107646
D001551	Benz(a)Anthracenes	Benz(a)Anthracenes analog results in increased expression of CYP1B1 mRNA	18205319
D001554	Benzene	Benzene results in decreased expression of CYP1B1 mRNA	20359517
C030233	benzo(a)pyrene-1,6-quinone	"CYP1B1 affects the metabolism of benzo(a)pyrene-1,6-quinone"	24025706
C014357	benzo(a)pyrene-6,12-quinone	"CYP1B1 affects the metabolism of benzo(a)pyrene-6,12-quinone"	24025706
C017228	benzo(a)pyrene 7,8-dihydrodiol	"benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	21028851
C017228	benzo(a)pyrene 7,8-dihydrodiol	"benzo(a)pyrene 7,8-dihydrodiol results in increased expression of CYP1B1 mRNA"	21028851
C017228	benzo(a)pyrene 7,8-dihydrodiol	"bergamottin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C017228	benzo(a)pyrene 7,8-dihydrodiol	"CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol"	15720144
C017228	benzo(a)pyrene 7,8-dihydrodiol	"CYP1B1 protein results in increased chemical synthesis of benzo(a)pyrene 7,8-dihydrodiol"	19879933
C017228	benzo(a)pyrene 7,8-dihydrodiol	"CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol"	15861043
C017228	benzo(a)pyrene 7,8-dihydrodiol	"imperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C017228	benzo(a)pyrene 7,8-dihydrodiol	"isoimperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C017228	benzo(a)pyrene 7,8-dihydrodiol	"isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C017228	benzo(a)pyrene 7,8-dihydrodiol	"NADP promotes the reaction [CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]"	15720144
C017228	benzo(a)pyrene 7,8-dihydrodiol	"CYP1B1 affects the metabolism of benzo(a)pyrene 7,8-dihydrodiol"	24025706
C043931	benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA	"CYP1B1 gene SNP affects the reaction [Coal Tar results in increased abundance of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA]"	27188524
C076588	benzo(a)pyrene-7,8-dione	"benzo(a)pyrene-7,8-dione results in increased expression of and results in increased activity of CYP1B1 protein"	16411658
C076588	benzo(a)pyrene-7,8-dione	"benzo(a)pyrene-7,8-dione results in increased expression of CYP1B1 mRNA"	16411658
C056612	benzo(a)pyrene-DNA adduct	[Benzo(a)pyrene results in increased expression of CYP1B1 protein] which results in increased abundance of benzo(a)pyrene-DNA adduct	22374940
C056612	benzo(a)pyrene-DNA adduct	CAT promotes the reaction [CYP1B1 gene SNP inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene-DNA adduct]]	23325794
C056612	benzo(a)pyrene-DNA adduct	CYP1B1 gene SNP inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene-DNA adduct]	23325794
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of CYP1B1 mRNA	27196671
C006703	benzo(b)fluoranthene	"[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA"	15566942
C006703	benzo(b)fluoranthene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CYP1B1 mRNA	27858113
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of CYP1B1 mRNA	12117779\|2637769
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene affects the expression of CYP1B1 mRNA	27099206
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]	27099206
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of CYP1B1 mRNA	17961608
C002615	benzo(c)phenanthrene	benzo(c)phenanthrene results in increased expression of CYP1B1 protein	9168260
C002615	benzo(c)phenanthrene	"[[benzo(c)phenanthrene results in increased expression of CYP1B1 protein] promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog"	9168260
C026487	benzo(e)pyrene	benzo(e)pyrene results in increased expression of CYP1B1 mRNA	27196671
C026487	benzo(e)pyrene	benzo(e)pyrene results in increased expression of CYP1B1 mRNA	12117779
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP1B1 mRNA	25251150
D019324	beta-Naphthoflavone	beta-Naphthoflavone binds to and results in decreased activity of CYP1B1 protein	19563207\|2105393
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP1B1 mRNA	12623754\|1499033
D019324	beta-Naphthoflavone	andrographolide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]	19737545
D019324	beta-Naphthoflavone	Apigenin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]	20930378
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP1B1 mRNA	19737545\|2093037
D019324	beta-Naphthoflavone	Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]	28428138
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP1B1 mRNA	19389873\|1969523
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP1B1 protein	25929820
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA	18164116\|2004503
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP1B1 mRNA	19464568\|1978606
C027704	benzo(j)fluoranthene	benzo(j)fluoranthene results in increased expression of CYP1B1 mRNA	27196671
C022921	benzo(k)fluoranthene	AHR2 mutant form inhibits the reaction [benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA]	21600235
C022921	benzo(k)fluoranthene	AHR2 mutant form inhibits the reaction [fluoranthene promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA]]	21600235
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA	21600235
C022921	benzo(k)fluoranthene	fluoranthene promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA]	21600235
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA	20471113
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene affects the reaction [CYP1B1 protein results in increased hydroxylation of Estradiol]	17919675
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA	15566942\|1725372
C022921	benzo(k)fluoranthene	CYP1B1 protein results in increased hydroxylation of benzo(k)fluoranthene	17919675
C022921	benzo(k)fluoranthene	"[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA"	15566942
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA	26377693
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 mRNA	25251150
D001564	Benzo(a)pyrene	alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19403181
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 mRNA	19403181\|2220925
D001564	Benzo(a)pyrene	CYP1B1 protein affects the metabolism of Benzo(a)pyrene	20599672
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 mRNA	20471113
D001564	Benzo(a)pyrene	"2,4,3',5'-tetramethoxystilbene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	21669939
D001564	Benzo(a)pyrene	"2',5'-dideoxyadenosine inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	22167199
D001564	Benzo(a)pyrene	2-aminoethoxydiphenyl borate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D001564	Benzo(a)pyrene	"3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]"	16484233
D001564	Benzo(a)pyrene	"3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	16530937\|1991960
D001564	Benzo(a)pyrene	"3',4'-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]"	16530937
D001564	Benzo(a)pyrene	"5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]"	16484233
D001564	Benzo(a)pyrene	"5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	16530937
D001564	Benzo(a)pyrene	"5,7-dimethoxyflavone inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]"	16530937
D001564	Benzo(a)pyrene	"8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]"	22167199
D001564	Benzo(a)pyrene	AHR mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1]	21452393
D001564	Benzo(a)pyrene	AR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of CYP1B1 mRNA]	15041469
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of CYP1B1 mRNA	20624995
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the reaction [CYP1B1 protein results in increased hydroxylation of Estradiol]	17919675
D001564	Benzo(a)pyrene	Benzo(a)pyrene analog results in increased expression of CYP1B1 mRNA	19365803
D001564	Benzo(a)pyrene	Benzo(a)pyrene analog results in increased expression of CYP1B1 protein	19365803
D001564	Benzo(a)pyrene	[Benzo(a)pyrene co-treated with Vehicle Emissions] results in decreased expression of CYP1B1 protein	20435083
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [Estradiol results in increased expression of CYP1B1 mRNA]	19619570
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased activity of CYP1B1 protein	15905203\|1648423
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1	21452393
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 mRNA	11854143\|1210764
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 protein	15297370\|1573500
D001564	Benzo(a)pyrene	[Benzo(a)pyrene results in increased expression of CYP1B1 protein] which results in increased abundance of benzo(a)pyrene-DNA adduct	22374940
D001564	Benzo(a)pyrene	Brefeldin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D001564	Benzo(a)pyrene	Butyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	27830268
D001564	Benzo(a)pyrene	Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	16237193
D001564	Benzo(a)pyrene	carnosol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22374940
D001564	Benzo(a)pyrene	carnosol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	22374940
D001564	Benzo(a)pyrene	CAT promotes the reaction [CYP1B1 gene SNP inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene-DNA adduct]]	23325794
D001564	Benzo(a)pyrene	chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19152381\|2016391
D001564	Benzo(a)pyrene	chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	20553787
D001564	Benzo(a)pyrene	cobaltous chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	20228066
D001564	Benzo(a)pyrene	CXCL8 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	28238931
D001564	Benzo(a)pyrene	CYP1B1 gene SNP inhibits the reaction [Benzo(a)pyrene results in increased abundance of benzo(a)pyrene-DNA adduct]	23325794
D001564	Benzo(a)pyrene	CYP1B1 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 mRNA]	24239969
D001564	Benzo(a)pyrene	CYP1B1 mutant form inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP7 mRNA]	24239969
D001564	Benzo(a)pyrene	CYP1B1 protein affects the metabolism of and results in increased activity of Benzo(a)pyrene	15958554
D001564	Benzo(a)pyrene	CYP1B1 protein polymorphism affects the metabolism of and results in increased activity of Benzo(a)pyrene	15958554
D001564	Benzo(a)pyrene	CYP1B1 protein polymorphism results in decreased metabolism of Benzo(a)pyrene	15958554
D001564	Benzo(a)pyrene	CYP1B1 protein results in increased hydrolysis of Benzo(a)pyrene	19919601
D001564	Benzo(a)pyrene	CYP1B1 protein results in increased metabolism of Benzo(a)pyrene	19879933
D001564	Benzo(a)pyrene	CYP1B1 protein results in increased susceptibility to Benzo(a)pyrene	27913846
D001564	Benzo(a)pyrene	[CYP1B1 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased mutagenesis of HPRT1 gene	27913846
D001564	Benzo(a)pyrene	[Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	15735009
D001564	Benzo(a)pyrene	[Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 protein	15735009
D001564	Benzo(a)pyrene	Estradiol promotes the reaction [Benzo(a)pyrene analog results in increased expression of CYP1B1 mRNA]	19365803
D001564	Benzo(a)pyrene	Estradiol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19365803
D001564	Benzo(a)pyrene	Grape Seed Proanthocyanidins inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	20146248
D001564	Benzo(a)pyrene	GUSB protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	26438400
D001564	Benzo(a)pyrene	ICI 118551 inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D001564	Benzo(a)pyrene	Particulate Matter inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19835593
D001564	Benzo(a)pyrene	"[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA"	15566942
D001564	Benzo(a)pyrene	Propranolol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D001564	Benzo(a)pyrene	resveratrol inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]	16484233
D001564	Benzo(a)pyrene	resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	11279601\|1516214
D001564	Benzo(a)pyrene	Suramin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D001564	Benzo(a)pyrene	TNF promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	25233930
D001564	Benzo(a)pyrene	trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	15713371
D001564	Benzo(a)pyrene	vorinostat inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	15713371
D001564	Benzo(a)pyrene	Zyflamend inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22374940
D001564	Benzo(a)pyrene	Zyflamend inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	22374940
D001564	Benzo(a)pyrene	[1-methylanthracene co-treated with fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	29170806
D001564	Benzo(a)pyrene	AHR protein affects the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]	11577022
D001564	Benzo(a)pyrene	AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	11577022
D001564	Benzo(a)pyrene	alpha-naphthoflavone inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]	11577022
D001564	Benzo(a)pyrene	[arsenite co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	15894712
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of CYP1B1 mRNA	15037607
D001564	Benzo(a)pyrene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CYP1B1 mRNA	27858113
D001564	Benzo(a)pyrene	Benzo(a)pyrene inhibits the reaction [Dust results in increased expression of CYP1B1 protein]	17060372
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [AHR protein binds to CYP1B1 promoter]	19654925
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [sodium bichromate results in increased expression of CYP1B1 mRNA]	22613061
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of CYP1B1 mRNA	26496743
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1B1 protein	11577022
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 mRNA	11577022\|1211777
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 protein	17060372\|1799738
D001564	Benzo(a)pyrene	[chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CYP1B1 mRNA	25820237
D001564	Benzo(a)pyrene	CYP1B1 protein results in increased susceptibility to Benzo(a)pyrene	21252291
D001564	Benzo(a)pyrene	Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	11577022
D001564	Benzo(a)pyrene	Dust inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	17060372
D001564	Benzo(a)pyrene	ellipticine inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]	11577022
D001564	Benzo(a)pyrene	Ethanol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22486318
D001564	Benzo(a)pyrene	MAPK14 protein promotes the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]	25233930
D001564	Benzo(a)pyrene	[resveratrol co-treated with Benzo(a)pyrene] results in decreased expression of CYP1B1 protein	18694800
D001564	Benzo(a)pyrene	[SOD1 protein co-treated with CAT protein] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19666105
D001564	Benzo(a)pyrene	[SOD1 protein co-treated with CAT protein] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	19666105
D001564	Benzo(a)pyrene	SOD1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19666105
D001564	Benzo(a)pyrene	SOD1 protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	19666105
D001564	Benzo(a)pyrene	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	21383588
D001564	Benzo(a)pyrene	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	21383588
D001564	Benzo(a)pyrene	"1,2,5,6-dibenzanthracene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]"	27099206
D001564	Benzo(a)pyrene	1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]	27099206
D001564	Benzo(a)pyrene	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	26086121
D001564	Benzo(a)pyrene	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	25233930
D001564	Benzo(a)pyrene	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]	25233930
D001564	Benzo(a)pyrene	AHR protein affects the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19497421
D001564	Benzo(a)pyrene	Benzo(a)pyrene affects the expression of CYP1B1 mRNA	27099206
D001564	Benzo(a)pyrene	[Benzo(a)pyrene co-treated with Oxygen] affects the expression of CYP1B1 protein	24657529
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [TNF protein promotes the reaction [CDK9 protein binds to CYP1B1 promoter]]	25233930
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [TNF protein promotes the reaction [POLR2A protein binds to CYP1B1 promoter]]	25233930
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]	21745554\|2523393
D001564	Benzo(a)pyrene	Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]	25233930
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of CYP1B1 mRNA	21839799
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased activity of CYP1B1 protein	15315710\|1949742
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 mRNA	15315710\|1619808
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP1B1 protein	16198082\|1623719
D001564	Benzo(a)pyrene	benzo(b)fluoranthene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]	27099206
D001564	Benzo(a)pyrene	chrysene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	15315710
D001564	Benzo(a)pyrene	CYP1B1 affects the metabolism of Benzo(a)pyrene	24025706
D001564	Benzo(a)pyrene	"dibenzo(a,l)pyrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]"	27099206
D001564	Benzo(a)pyrene	Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]]	25233930
D001564	Benzo(a)pyrene	Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]]	25233930
D001564	Benzo(a)pyrene	EGF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	25233930
D001564	Benzo(a)pyrene	EGF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	25233930
D001564	Benzo(a)pyrene	fluoranthene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]	27099206
D001564	Benzo(a)pyrene	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	25233930
D001564	Benzo(a)pyrene	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]	25233930
D001564	Benzo(a)pyrene	Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	16198082
D001564	Benzo(a)pyrene	TNF promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	25233930
D001564	Benzo(a)pyrene	TNF promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	25233930
D001564	Benzo(a)pyrene	TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	21745554
D001564	Benzo(a)pyrene	TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	21745554
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CYP1B1 mRNA"	20018196
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CYP1B1 mRNA"	17944540\|1915039
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"CYP1B1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"	15720144\|1595855
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"CYP1B1 protein polymorphism affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"	15958554
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"CYP1B1 protein polymorphism results in decreased chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"	15958554
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	"NADP promotes the reaction [CYP1B1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide]"	15720144
C006710	benzotriphenylene	benzotriphenylene results in increased expression of CYP1B1 mRNA	17253728
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of CYP1B1 protein	15486049
C057754	benzyloxyresorufin	CYP1B1 protein affects the metabolism of benzyloxyresorufin	20599672
C054108	benzyl selenocyanate	benzyl selenocyanate binds to and results in decreased activity of CYP1B1 protein	21732699
C068337	bergamottin	"bergamottin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C068337	bergamottin	bergamottin results in decreased activity of CYP1B1 protein	15861043
C068337	bergamottin	bergamottin results in decreased activity of CYP1B1 protein polymorphism	15861043
D004958	Estradiol	ARNT gene mutant form inhibits the reaction [Estradiol promotes the reaction [AHR protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	ARNT gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [AHR protein binds to CYP1B1 promoter]]]	24299737
D004958	Estradiol	Benzo(a)pyrene affects the reaction [CYP1B1 protein results in increased hydroxylation of Estradiol]	17919675
D004958	Estradiol	Benzo(a)pyrene promotes the reaction [Estradiol results in increased expression of CYP1B1 mRNA]	19619570
D004958	Estradiol	benzo(k)fluoranthene affects the reaction [CYP1B1 protein results in increased hydroxylation of Estradiol]	17919675
D004958	Estradiol	CYP1B1 protein affects the metabolism of Estradiol	15142886\|1550751
D004958	Estradiol	CYP1B1 protein polymorphism results in increased hydroxylation of Estradiol	15285606
D004958	Estradiol	CYP1B1 protein results in increased hydroxylation of Estradiol	11074351\|1576359
D004958	Estradiol	CYP1B1 protein results in increased oxidation of Estradiol	15377160
D004958	Estradiol	Estradiol binds to and results in decreased activity of CYP1B1 protein	19563207
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in increased expression of CYP1B1 mRNA	20660070
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA	19619570
D004958	Estradiol	Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	15837795
D004958	Estradiol	"Estradiol promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21513769
D004958	Estradiol	Estradiol promotes the reaction [AHR protein binds to CYP1B1 promoter]	24299737
D004958	Estradiol	Estradiol promotes the reaction [ARNT protein binds to CYP1B1 promoter]	24299737
D004958	Estradiol	Estradiol promotes the reaction [Benzo(a)pyrene analog results in increased expression of CYP1B1 mRNA]	19365803
D004958	Estradiol	Estradiol promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19365803
D004958	Estradiol	Estradiol promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]	23524099
D004958	Estradiol	Estradiol promotes the reaction [ESR1 protein binds to CYP1B1 promoter]	22071320\|2429973
D004958	Estradiol	Estradiol promotes the reaction [NRIP1 protein binds to CYP1B1 promoter]	22071320
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [NCOA3 protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	15157572
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19619570
D004958	Estradiol	Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	19619570
D004958	Estradiol	Estradiol results in decreased expression of CYP1B1 mRNA	16474171
D004958	Estradiol	Estradiol results in increased activity of CYP1B1 protein	15157572
D004958	Estradiol	Estradiol results in increased expression of CYP1B1 mRNA	16474171\|1961957
D004958	Estradiol	resveratrol inhibits the reaction [CYP1B1 protein affects the metabolism of Estradiol]	15142886
D004958	Estradiol	Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [AHR protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	24299737
D004958	Estradiol	Estradiol results in increased expression of CYP1B1 mRNA	16280380
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1B1 mRNA]	16280380
D004958	Estradiol	[Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
D004958	Estradiol	"Estradiol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	26945725
D004958	Estradiol	Estradiol results in increased expression of CYP1B1 mRNA	8674863
D004958	Estradiol	Estradiol results in increased expression of CYP1B1 protein	8674863
D004958	Estradiol	CYP1B1 protein results in increased hydroxylation of Estradiol	10910964\|1590809
D004958	Estradiol	CYP1B1 protein results in increased metabolism of Estradiol	18456490
C095105	bexarotene	bexarotene results in increased expression of CYP1B1 mRNA	16648578
C004541	biochanin A	biochanin A results in decreased activity of CYP1B1 protein	20391625
C004541	biochanin A	biochanin A results in increased expression of CYP1B1 mRNA	28985473
C004541	biochanin A	CYP1B1 protein results in decreased methylation of biochanin A	15479032
D001710	Biotin	Biotin results in increased expression of and results in increased activity of CYP1B1 protein	15333708
D001710	Biotin	Biotin results in increased expression of CYP1B1 mRNA	15219929\|1533370
C543008	bis(4-hydroxyphenyl)sulfone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CYP1B1 mRNA	28628672
C006780	bisphenol A	bisphenol A affects the expression of CYP1B1 mRNA	20170705
C006780	bisphenol A	bisphenol A results in decreased expression of CYP1B1 mRNA	16474171
C006780	bisphenol A	bisphenol A results in increased expression of and affects the localization of CYP1B1 protein	29275510
C006780	bisphenol A	bisphenol A results in increased expression of CYP1B1 mRNA	16474171\|2352409
C006780	bisphenol A	butylparaben promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]	23524099
C006780	bisphenol A	Estradiol promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]	23524099
C006780	bisphenol A	triclocarban promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]	23524099
C006780	bisphenol A	bisphenol A results in decreased expression of CYP1B1 mRNA	22687993\|2392831
C006780	bisphenol A	bisphenol A results in increased expression of CYP1B1 mRNA	25594700
C006780	bisphenol A	bisphenol A results in decreased expression of CYP1B1 mRNA	12075121
C006780	bisphenol A	bisphenol A results in decreased expression of CYP1B1 protein	24752506
C006780	bisphenol A	bisphenol A results in increased expression of CYP1B1 mRNA	25181051
D020126	Brefeldin A	Brefeldin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 mRNA	22079614
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 mRNA	7588239
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP1B1 protein	7588239
C027561	butylbenzyl phthalate	"3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]"	22138065
C027561	butylbenzyl phthalate	"3',4'-dimethoxyflavone inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]"	22138065
C027561	butylbenzyl phthalate	AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 mRNA]	22138065
C027561	butylbenzyl phthalate	AHR mutant form inhibits the reaction [butylbenzyl phthalate results in increased expression of CYP1B1 protein]	22138065
C027561	butylbenzyl phthalate	butylbenzyl phthalate promotes the reaction [AHR protein binds to CYP1B1 promoter]	22138065
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in increased expression of CYP1B1 mRNA	22138065
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in increased expression of CYP1B1 protein	22138065
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of CYP1B1 mRNA	12414654
C038091	butylparaben	butylparaben promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]	23524099
C038091	butylparaben	butylparaben results in increased expression of CYP1B1 mRNA	23524099
D020148	Butyric Acid	Butyric Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	27830268
C584509	C646 compound	C646 compound results in decreased expression of CYP1B1 mRNA	26191083
D019256	Cadmium Chloride	Cadmium Chloride affects the expression of CYP1B1 mRNA	25596134
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of CYP1B1 mRNA	12760830\|1856053
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of CYP1B1 mRNA	11958953
D002110	Caffeine	Caffeine results in decreased activity of CYP1B1 protein	18420780
D002118	Calcium	Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	16237193
D002118	Calcium	Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	16237193
D002118	Calcium	Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19782052
C059041	calyculin A	calyculin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10696073
D002248	Carbon Monoxide	Carbon Monoxide promotes the reaction [1-ethynylpyrene results in increased expression of CYP1B1 mRNA]	10581206
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of CYP1B1 mRNA	17484886
C010063	carbonyl sulfide	carbonyl sulfide results in increased expression of CYP1B1 mRNA	19395590
C068623	carnosol	carnosol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22374940
C068623	carnosol	carnosol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	22374940
D002509	Cephaloridine	Cephaloridine results in increased expression of CYP1B1 mRNA	18500788
C016299	chelerythrine	"chelerythrine inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446
C016299	chelerythrine	chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10037446
C016299	chelerythrine	chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	10037446
C004656	chloroacetaldehyde	chloroacetaldehyde affects the expression of CYP1B1 mRNA	25596134
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1B1 mRNA	17851650
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of CYP1B1 mRNA	11323195\|1817854
D020245	p-Chloromercuribenzoic Acid	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
D020245	p-Chloromercuribenzoic Acid	p-Chloromercuribenzoic Acid results in increased expression of CYP1B1 mRNA	26272509
C007020	chlorophyllin	chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19152381\|2016391
C007020	chlorophyllin	chlorophyllin results in increased expression of CYP1B1 mRNA	19152381
C100187	chloropicrin	chloropicrin affects the expression of CYP1B1 mRNA	26352163
C100187	chloropicrin	chloropicrin results in increased expression of CYP1B1 mRNA	28476498
D002737	Chloroprene	Chloroprene results in increased expression of CYP1B1 mRNA	23125180
D002746	Chlorpromazine	Chlorpromazine affects the expression of CYP1B1 mRNA	25064622
D002746	Chlorpromazine	CYP1B1 protein results in decreased susceptibility to Chlorpromazine	26477383
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of CYP1B1 mRNA	19326769
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP1B1 mRNA	20938992
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYP1B1 gene	20938992
D002857	Chromium	Chromium results in decreased expression of CYP1B1 mRNA	21437242
C074702	chromium hexavalent ion	[chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CYP1B1 mRNA	25820237
C031180	chrysene	chrysene results in increased expression of CYP1B1 mRNA	12107646\|1556694
C031180	chrysene	[Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of CYP1B1 mRNA	27858113
C031180	chrysene	chrysene results in increased expression of CYP1B1 mRNA	12117779
C031180	chrysene	chrysene inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	15315710
C031180	chrysene	chrysene results in increased expression of CYP1B1 mRNA	17961608
C043561	chrysin	chrysin binds to and results in decreased activity of CYP1B1 protein	21053930
C043561	chrysin	chrysin results in decreased activity of CYP1B1 protein	21482471
C043561	chrysin	CYP1B1 protein results in increased metabolism of chrysin	19666078
C043561	chrysin	[CYP1B1 protein results in increased metabolism of chrysin] which results in increased chemical synthesis of baicalein	19666078
C007054	chrysoeriol	chrysoeriol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	20553787
C027113	chrysophanic acid	chrysophanic acid results in decreased activity of CYP1B1 protein	27633141
C418118	CI 1044	CI 1044 results in increased expression of CYP1B1 mRNA	17569694
C059262	cidofovir	cidofovir results in increased expression of CYP1B1 mRNA	25596134
C039824	cirsiliol	cirsiliol results in decreased activity of CYP1B1 protein	21482471
C039824	cirsiliol	cirsiliol results in increased expression of CYP1B1 mRNA	19601638
C039824	cirsiliol	CYP1B1 protein results in increased metabolism of cirsiliol	19601638
C551788	CL 075	"CL 075 promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA]"	27783115
C551788	CL 075	CL 075 promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	27783115
C551788	CL 075	CL 075 results in increased expression of CYP1B1 mRNA	27783115
D004002	Clodronic Acid	Clodronic Acid results in increased expression of CYP1B1 mRNA	25596134
D003024	Clozapine	CYP1B1 protein results in increased metabolism of Clozapine	18809730
C079149	clozapine N-oxide	CYP1B1 protein results in increased chemical synthesis of clozapine N-oxide	18809730
D003033	Coal Tar	Coal Tar results in increased expression of CYP1B1 mRNA	16882163\|2334873
D003033	Coal Tar	Coal Tar results in increased expression of CYP1B1 protein	15720126
D003033	Coal Tar	"CYP1B1 gene SNP affects the reaction [Coal Tar results in increased abundance of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA]"	27188524
D003033	Coal Tar	Coal Tar results in decreased expression of CYP1B1 mRNA	27858113
D003033	Coal Tar	[Vehicle Emissions analog co-treated with Coal Tar analog co-treated with Tobacco Smoke Pollution analog] results in increased expression of CYP1B1 mRNA	22935520\|2327456
D003033	Coal Tar	[Vehicle Emissions analog co-treated with Coal Tar analog] results in increased expression of CYP1B1 mRNA	22935520\|2327456
D003035	Cobalt	[tungsten carbide co-treated with Cobalt] results in decreased expression of CYP1B1 mRNA	18078969
C018021	cobaltous chloride	cobaltous chloride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	20228066
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of CYP1B1 mRNA	19376846
D009249	NADP	"alpha-naphthoflavone inhibits the reaction [[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene]"	16120791
D009249	NADP	"[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,2',4,6'-tetramethoxystilbene"	19463925
D009249	NADP	"[CYP1B1 protein co-treated with NADP] results in increased metabolism of 2,4,3',5'-tetramethoxystilbene"	16120791
D009249	NADP	"NADP promotes the reaction [CYP1B1 protein affects the chemical synthesis of 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide]"	15720144
D009249	NADP	"NADP promotes the reaction [CYP1B1 protein affects the metabolism of and results in increased activity of benzo(a)pyrene 7,8-dihydrodiol]"	15720144
D005576	Colforsin	Colforsin results in increased expression of CYP1B1 mRNA	7588239
D005576	Colforsin	Colforsin results in increased expression of CYP1B1 protein	7588239
D003300	Copper	[NSC 689534 binds to Copper] which results in increased expression of CYP1B1 mRNA	20971185
D019327	Copper Sulfate	Copper Sulfate results in increased expression of CYP1B1 mRNA	12860252\|1954981
D003375	Coumestrol	[Coumestrol co-treated with resveratrol] results in increased expression of CYP1B1 mRNA	19167446
D003375	Coumestrol	Coumestrol results in increased expression of CYP1B1 mRNA	19167446
D003474	Curcumin	Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19018768
D003474	Curcumin	Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	19018768
D003474	Curcumin	Curcumin results in decreased expression of CYP1B1 mRNA	17637178
D003513	Cycloheximide	Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	9145908
D003513	Cycloheximide	Cycloheximide results in increased expression of CYP1B1 mRNA	19684285
D003513	Cycloheximide	[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA	19684285
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]	21867498
D003520	Cyclophosphamide	Cyclophosphamide results in decreased expression of CYP1B1 mRNA	12167460
D016572	Cyclosporine	Cyclosporine affects the expression of CYP1B1 mRNA	25064622
D016572	Cyclosporine	Cyclosporine results in decreased expression of CYP1B1 mRNA	25596134
D016572	Cyclosporine	Cyclosporine results in increased expression of CYP1B1 mRNA	20106945
C089595	cylindrospermopsin	cylindrospermopsin results in increased expression of CYP1B1 mRNA	23726867
C017160	cypermethrin	cypermethrin results in decreased activity of CYP1B1 protein	18420780
D015084	2,4-Dichlorophenoxyacetic Acid	"2,4-Dichlorophenoxyacetic Acid results in increased expression of CYP1B1 mRNA"	10910964
D003609	Dactinomycin	Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1B1 mRNA]	11752201
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	11577022
D003609	Dactinomycin	Dactinomycin results in decreased expression of CYP1B1 mRNA	11577022
D003609	Dactinomycin	Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]	21867498
C004742	daidzein	CYP1B1 protein affects the chemical synthesis of daidzein	15479032
C004742	daidzein	daidzein results in decreased activity of CYP1B1 protein	15479032
C004742	daidzein	daidzein results in decreased activity of CYP1B1 protein	18420780
D000069439	Dasatinib	Dasatinib results in increased expression of CYP1B1 mRNA	20579391
D003630	Daunorubicin	CYP1B1 affects the susceptibility to Daunorubicin	18451141
D003634	DDT	[indole-3-carbinol co-treated with DDT] results in increased expression of CYP1B1 mRNA	17311112
C014347	decitabine	decitabine affects the expression of CYP1B1 mRNA	17145863
C014347	decitabine	decitabine affects the methylation of CYP1B1 gene	17630775
C014347	decitabine	decitabine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20631054
C014347	decitabine	decitabine results in decreased methylation of CYP1B1 promoter	20631054
D003687	Dehydroepiandrosterone	"Dehydroepiandrosterone inhibits the reaction [benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10497882
D003687	Dehydroepiandrosterone	Dehydroepiandrosterone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	10497882
D003687	Dehydroepiandrosterone	"Dehydroepiandrosterone inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10497882
D003687	Dehydroepiandrosterone	"Dehydroepiandrosterone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10497882
D003687	Dehydroepiandrosterone	Dehydroepiandrosterone results in increased expression of CYP1B1 mRNA	10497882
D003849	Deoxyguanosine	CYP1B1 protein promotes the reaction [Aflatoxin B1 binds to Deoxyguanosine]	21907773
C007262	deoxynivalenol	deoxynivalenol results in decreased expression of CYP1B1 mRNA	20702593
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CYP1B1 mRNA	28628672
D003907	Dexamethasone	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 mRNA	15967407
D003907	Dexamethasone	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 protein	15967407
D003907	Dexamethasone	Dexamethasone results in increased expression of CYP1B1 mRNA	21041162
D003907	Dexamethasone	Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9804617
D003907	Dexamethasone	Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	9804617
D003907	Dexamethasone	Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	17690134
D003907	Dexamethasone	Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	9804617
D003907	Dexamethasone	Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	17690134
D003976	Diazinon	Diazinon results in decreased expression of CYP1B1 mRNA	29108742
C041516	dibenzo(a,e)pyrene	"dibenzo(a,e)pyrene results in increased expression of CYP1B1 mRNA"	17961608
C041517	dibenzo(a,l)pyrene	"CYP1B1 protein results in increased metabolism of dibenzo(a,l)pyrene"	21527924
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene results in increased expression of CYP1B1 mRNA"	15566942
C041517	dibenzo(a,l)pyrene	"[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP1B1 mRNA"	17612574
C041517	dibenzo(a,l)pyrene	"[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA"	15566942
C041517	dibenzo(a,l)pyrene	"[Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP1B1 mRNA"	17612574
C041517	dibenzo(a,l)pyrene	"CYP1B1 gene mutant form results in decreased susceptibility to dibenzo(a,l)pyrene"	26049101
C041517	dibenzo(a,l)pyrene	"CYP1B1 protein results in increased activity of dibenzo(a,l)pyrene"	15606143
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene promotes the reaction [Dust results in increased expression of CYP1B1 protein]"	17060372
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene results in decreased expression of CYP1B1 mRNA"	23274566
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene results in increased expression of CYP1B1 mRNA"	12117779\|2649674
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene results in increased expression of CYP1B1 protein"	17060372
C041517	dibenzo(a,l)pyrene	"Dust promotes the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1B1 protein]"	17060372
C041517	dibenzo(a,l)pyrene	"[2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein] which results in decreased activity of dibenzo(a,l)pyrene"	17961608
C041517	dibenzo(a,l)pyrene	"[2,4,3',5'-tetramethoxystilbene results in decreased activity of CYP1B1 protein] which results in decreased susceptibility to dibenzo(a,l)pyrene"	17961608
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene affects the expression of CYP1B1 mRNA"	27099206
C041517	dibenzo(a,l)pyrene	"dibenzo(a,l)pyrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]"	27099206
C041517	dibenzo(a,l)pyrene	"[fluoranthene results in decreased activity of CYP1B1 protein] which results in decreased activity of dibenzo(a,l)pyrene"	17961608
C041517	dibenzo(a,l)pyrene	"[fluoranthene results in decreased activity of CYP1B1 protein] which results in decreased susceptibility to dibenzo(a,l)pyrene"	17961608
C041517	dibenzo(a,l)pyrene	"CYP1B1 protein results in increased metabolism of and results in increased activity of dibenzo(a,l)pyrene"	17961608
D000072338	Dibenzofurans, Polychlorinated	"[Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1B1 mRNA"	17850846
D000072338	Dibenzofurans, Polychlorinated	"[Polychlorinated Biphenyls co-treated with Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1B1 mRNA"	15858227
C016366	dibenzothiophene	dibenzothiophene results in increased expression of CYP1B1 mRNA	23656968
C088674	dibromoacetic acid	dibromoacetic acid results in decreased expression of CYP1B1 mRNA	21046364
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of and results in increased activity of CYP1B1 protein	16040568
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of CYP1B1 mRNA	16040568
D003994	Bucladesine	Bucladesine results in increased expression of CYP1B1 mRNA	11559018
D002945	Cisplatin	[Cisplatin co-treated with jinfukang] results in increased expression of CYP1B1 mRNA	27392435
D002945	Cisplatin	Cisplatin results in increased expression of CYP1B1 mRNA	25596134\|2759478
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of CYP1B1 mRNA	16040568
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 mRNA]]	25233930
D004004	Dichlororibofuranosylbenzimidazole	Dichlororibofuranosylbenzimidazole inhibits the reaction [Benzo(a)pyrene promotes the reaction [TNF protein results in increased expression of CYP1B1 protein]]	25233930
D004008	Diclofenac	Diclofenac results in decreased activity of CYP1B1 protein	18420780
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate results in increased expression of CYP1B1 mRNA	26924002
D004026	Dieldrin	Dieldrin results in increased expression of CYP1B1 mRNA	10910964
D004040	Dietary Carbohydrates	Dietary Carbohydrates results in increased expression of CYP1B1 mRNA	17490981
D004041	Dietary Fats	"[9,10-Dimethyl-1,2-benzanthracene co-treated with Dietary Fats] results in decreased expression of CYP1B1 mRNA"	19750107
D004041	Dietary Fats	CYP1B1 protein affects the reaction [Dietary Fats affects the expression of KRT23]	27036855
D004041	Dietary Fats	CYP1B1 protein affects the reaction [Dietary Fats results in increased expression of INS1 protein]	27036855
D004041	Dietary Fats	CYP1B1 protein affects the reaction [Dietary Fats results in increased expression of LEP protein]	27036855
D004041	Dietary Fats	CYP1B1 protein results in increased susceptibility to Dietary Fats	27036855
D004041	Dietary Fats	[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA	26102010
D004041	Dietary Fats	[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein	26102010
D004041	Dietary Fats	Dietary Fats results in decreased expression of CYP1B1 mRNA	18042831
D004041	Dietary Fats	[Tetrachlorodibenzodioxin co-treated with Dietary Fats] results in increased expression of CYP1B1 mRNA	20435547
D004041	Dietary Fats	tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA]	26102010
D004041	Dietary Fats	tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein]	26102010
D004041	Dietary Fats	Dietary Fats results in decreased expression of CYP1B1 mRNA	21852083
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of and results in increased activity of CYP1B1 protein	16040568
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of CYP1B1 mRNA	16040568
D004052	Diethylnitrosamine	Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA]	22129741
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA	18164116\|2004503
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of CYP1B1 mRNA	27565560
D004052	Diethylnitrosamine	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA	22129741
C007379	diethyl phthalate	diethyl phthalate results in increased expression of and results in increased activity of CYP1B1 protein	16040568
C007379	diethyl phthalate	diethyl phthalate results in increased expression of CYP1B1 mRNA	16040568
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CYP1B1 mRNA	21041162
D004054	Diethylstilbestrol	[Diethylstilbestrol co-treated with allyl sulfide] results in increased expression of CYP1B1 mRNA	17129689
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased expression of CYP1B1 mRNA	21658437
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CYP1B1 mRNA	17129689
D004087	Dihydroergotamine	Dihydroergotamine results in decreased activity of CYP1B1 protein	18420780
D015127	9,10-Dimethyl-1,2-benzanthracene	"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	19276279
D015127	9,10-Dimethyl-1,2-benzanthracene	"2'-hydroxychalcone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	15596260
D015127	9,10-Dimethyl-1,2-benzanthracene	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein]"	17183067
D015127	9,10-Dimethyl-1,2-benzanthracene	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	17183067
D015127	9,10-Dimethyl-1,2-benzanthracene	"5-androstene-16-fluoro-17-one inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	12097275
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1B1 protein"	17183067
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA"	12097275\|1559626
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein"	25110319
D015127	9,10-Dimethyl-1,2-benzanthracene	"[[benzo(c)phenanthrene results in increased expression of CYP1B1 protein] promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]] which results in increased chemical synthesis of 9,10-Dimethyl-1,2-benzanthracene analog"	9168260
D015127	9,10-Dimethyl-1,2-benzanthracene	"Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	17275817
D015127	9,10-Dimethyl-1,2-benzanthracene	"Eugenol inhibits the reaction [CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]"	17275817
D015127	9,10-Dimethyl-1,2-benzanthracene	"isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	25110319
D015127	9,10-Dimethyl-1,2-benzanthracene	"isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]"	25110319
D015127	9,10-Dimethyl-1,2-benzanthracene	"S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	19276279
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1B1 protein"	22044346
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA"	22044346
D015127	9,10-Dimethyl-1,2-benzanthracene	"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1B1 protein]"	22044346
D015127	9,10-Dimethyl-1,2-benzanthracene	"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	22044346
D015127	9,10-Dimethyl-1,2-benzanthracene	"1-ethynylpyrene inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10581206
D015127	9,10-Dimethyl-1,2-benzanthracene	"[9,10-Dimethyl-1,2-benzanthracene co-treated with Dietary Fats] results in decreased expression of CYP1B1 mRNA"	19750107
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1B1 protein"	15667830
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA"	11559018\|1211777
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein"	22595614
D015127	9,10-Dimethyl-1,2-benzanthracene	"benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446\|1049788
D015127	9,10-Dimethyl-1,2-benzanthracene	"chelerythrine inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene"	15331171\|1744266
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of AHRR mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CREB3L3 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CXCL10 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of CYP1A1 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of EGR2 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of ERDR1 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HBB-B1 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HOXB6 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of HSPA1A mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of IL6 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of NR4A1 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of POLR2A mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of RAG1 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of SOX19 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of SPP1 mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"[CYP1B1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene] which affects the expression of TNF mRNA"	27891153
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased activity of 9,10-Dimethyl-1,2-benzanthracene"	15606143
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"	10037446\|1049788
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene"	11323178\|1558070
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 results in increased susceptibility to 9,10-Dimethyl-1,2-benzanthracene"	20171256
D015127	9,10-Dimethyl-1,2-benzanthracene	"Dehydroepiandrosterone inhibits the reaction [benz(a)anthracene promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10497882
D015127	9,10-Dimethyl-1,2-benzanthracene	"Dehydroepiandrosterone inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10497882
D015127	9,10-Dimethyl-1,2-benzanthracene	"Dehydroepiandrosterone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10497882
D015127	9,10-Dimethyl-1,2-benzanthracene	"[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D015127	9,10-Dimethyl-1,2-benzanthracene	"[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D015127	9,10-Dimethyl-1,2-benzanthracene	"[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D015127	9,10-Dimethyl-1,2-benzanthracene	"[Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D015127	9,10-Dimethyl-1,2-benzanthracene	"POR protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]"	22595614
D015127	9,10-Dimethyl-1,2-benzanthracene	"PRKCB protein inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446
D015127	9,10-Dimethyl-1,2-benzanthracene	"PRKCB protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10037446
D015127	9,10-Dimethyl-1,2-benzanthracene	"[resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D015127	9,10-Dimethyl-1,2-benzanthracene	"Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446\|1049788
D015127	9,10-Dimethyl-1,2-benzanthracene	"Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446
D015127	9,10-Dimethyl-1,2-benzanthracene	"Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10037446
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA"	18205319\|2694572
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"	7588239\|8674863
D015127	9,10-Dimethyl-1,2-benzanthracene	"Estradiol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	26945725
D015127	9,10-Dimethyl-1,2-benzanthracene	"POMC protein promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	7588239
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased activity of and results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"	17204581
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene"	19027032\|2544868
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene"	17275817
C024629	dimethyl phthalate	dimethyl phthalate results in increased expression of CYP1B1 mRNA	26924002
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide affects the expression of CYP1B1 mRNA	12843640
C039602	diosmetin	diosmetin results in decreased activity of CYP1B1 protein	21482471
D004147	Dioxins	Dioxins promotes the reaction [AHR protein binds to CYP1B1 enhancer]	20631054
D004147	Dioxins	Dioxins promotes the reaction [KAT2B protein binds to CYP1B1 enhancer]	20631054
D004147	Dioxins	Dioxins results in increased expression of CYP1B1 mRNA	20631054
C010574	diphenyl	diphenyl binds to and results in decreased activity of CYP1B1 protein	19563207
C493087	diphenylarsinic acid	diphenylarsinic acid results in increased expression of CYP1B1 mRNA	23999541
D004237	Diuron	Diuron metabolite results in increased expression of CYP1B1 mRNA	24172598
D004237	Diuron	Diuron results in decreased expression of CYP1B1 mRNA	25152437
D004237	Diuron	Diuron results in increased expression of CYP1B1 mRNA	21551480
C521792	DMU-212	DMU-212 affects the expression of CYP1B1 mRNA	26428916
C521792	DMU-212	DMU-212 results in decreased expression of CYP1B1 mRNA	22687606\|2405589
C521792	DMU-212	DMU-212 results in decreased expression of CYP1B1 protein	22687606
C067311	docetaxel	CYP1B1 gene polymorphism affects the susceptibility to docetaxel	18187806
D004298	Dopamine	Dopamine results in decreased activity of CYP1B1 protein	18420780
D004317	Doxorubicin	Doxorubicin results in increased expression of CYP1B1 mRNA	21040762
D004317	Doxorubicin	[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of CYP1B1 mRNA	21040762
D004317	Doxorubicin	Doxorubicin results in increased expression of CYP1B1 mRNA	19796650
D004317	Doxorubicin	Doxorubicin results in increased expression of CYP1B1 protein	19796650
D004318	Doxycycline	[[Doxycycline results in increased expression of AHR protein] which co-treated with Tobacco Smoke Pollution] results in increased expression of CYP1B1 mRNA	22273977
D004318	Doxycycline	[Doxycycline results in increased expression of AHR protein] which results in increased expression of CYP1B1 mRNA	22273977
C038345	droloxifene	droloxifene results in decreased activity of CYP1B1 protein	12419016
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	16901605
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased expression of CYP1B1 mRNA"	16901605
D004391	Dust	[Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	15735009
D004391	Dust	[Dust co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 protein	15735009
D004391	Dust	Dust results in decreased activity of CYP1B1 protein	17060372
D004391	Dust	Dust results in increased expression of CYP1B1 mRNA	15735009\|1780542
D004391	Dust	Dust results in increased expression of CYP1B1 protein	15735009
D004391	Dust	Benzo(a)pyrene inhibits the reaction [Dust results in increased expression of CYP1B1 protein]	17060372
D004391	Dust	"dibenzo(a,l)pyrene promotes the reaction [Dust results in increased expression of CYP1B1 protein]"	17060372
D004391	Dust	Dust inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	17060372
D004391	Dust	"Dust promotes the reaction [dibenzo(a,l)pyrene results in increased expression of CYP1B1 protein]"	17060372
D004391	Dust	Dust results in increased expression of CYP1B1 protein	17060372
C509867	E804 bisindole	E804 bisindole results in increased expression of CYP1B1 mRNA	29209748
D004610	Ellagic Acid	"[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D004610	Ellagic Acid	"[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D004610	Ellagic Acid	Ellagic Acid results in decreased activity of CYP1B1 protein	19329757
C034192	ellipticine	CYP1B1 protein results in increased metabolism of ellipticine	22917556
C034192	ellipticine	ellipticine inhibits the reaction [AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]]	11577022
D004642	Emodin	Emodin results in decreased activity of CYP1B1 protein	27633141
D004642	Emodin	Emodin results in increased expression of CYP1B1 mRNA	11502733\|1499033
D004642	Emodin	Emodin results in increased expression of CYP1B1 protein	11502733
D004785	Environmental Pollutants	CYP1B1 gene polymorphism results in increased susceptibility to Environmental Pollutants	15075793
C045651	epigallocatechin gallate	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CYP1B1 mRNA	22079256
C091891	epsilon-viniferin	epsilon-viniferin results in decreased activity of CYP1B1 protein	12818727
C073539	erucin	erucin results in increased expression of CYP1B1 protein	18823965\|2083322
C074283	estradiol 3-benzoate	estradiol 3-benzoate results in decreased expression of CYP1B1 protein	24752506
D004967	Estrogens	CYP1B1 gene polymorphism affects the metabolism of Estrogens	15777990\|1685024
D004967	Estrogens	CYP1B1 gene polymorphism affects the susceptibility to [Estrogens co-treated with Medroxyprogesterone Acetate]	15987428
D004967	Estrogens	CYP1B1 protein affects the metabolism of Estrogens	15987428
D004967	Estrogens	CYP1B1 protein results in increased hydroxylation of Estrogens	15734958
D004967	Estrogens	CYP1B1 protein results in increased hydroxylation of Estrogens	15342454
D004970	Estrone	CYP1B1 protein binds to Estrone	27966929
D004970	Estrone	CYP1B1 protein polymorphism affects the hydroxylation of Estrone	16207128
D004970	Estrone	CYP1B1 protein results in increased hydroxylation of Estrone	15763594
D004970	Estrone	Estrone binds to and results in decreased activity of CYP1B1 protein	19563207
D004970	Estrone	CYP1B1 protein results in increased hydroxylation of Estrone	28985473
D004970	Estrone	[CYP1B1 protein results in increased hydroxylation of Estrone] which results in increased chemical synthesis of 4-hydroxyestrone	28985473
D004970	Estrone	[[CYP1B1 protein results in increased hydroxylation of Estrone] which results in increased chemical synthesis of 4-hydroxyestrone] which results in increased abundance of 4-hydroxyestrone-4-methyl ether	28985473
D000431	Ethanol	Ethanol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22486318
D000431	Ethanol	Ethanol inhibits the reaction [Ethanol results in increased expression of CYP1B1 mRNA]	22486318
D000431	Ethanol	Ethanol promotes the reaction [AHR protein binds to CYP1B1 promoter]	22486318
D000431	Ethanol	[Ethanol promotes the reaction [AHR protein binds to CYP1B1 promoter]] which results in increased expression of CYP1B1 mRNA	22486318\|2248631
D000431	Ethanol	Ethanol results in increased expression of CYP1B1 mRNA	22486318
D000431	Ethanol	Ethanol results in increased expression of CYP1B1 mRNA	23273579
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of CYP1B1 mRNA	25064622
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of CYP1B1 mRNA	12075121
D005015	Ethoxyquin	Ethoxyquin results in increased expression of CYP1B1 mRNA	19695238
C004912	ethylbenzene	ethylbenzene results in decreased expression of CYP1B1 mRNA	20359517
C002994	ethylene dimethanesulfonate	ethylene dimethanesulfonate results in decreased expression of CYP1B1 mRNA	22711419
C039614	ethylisopropylamiloride	ethylisopropylamiloride results in decreased activity of CYP1B1 protein	15081870
D005054	Eugenol	"Eugenol inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	17275817
D005054	Eugenol	"Eugenol inhibits the reaction [CYP1B1 protein results in increased metabolism of and results in increased activity of 9,10-Dimethyl-1,2-benzanthracene]"	17275817
D005054	Eugenol	Eugenol results in decreased activity of CYP1B1 protein	17275817
C103110	eupatorin	CYP1B1 protein results in increased metabolism of eupatorin analog	21482471
C103110	eupatorin	eupatorin results in decreased activity of CYP1B1 protein	21482471
C103110	eupatorin	eupatorin results in increased expression of CYP1B1 mRNA	19601638
C000593130	eupatorin-5-methyl ether	eupatorin-5-methyl ether results in increased expression of CYP1B1 mRNA	23994263
D015025	Zearalenone	Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	15157572
D015025	Zearalenone	Zearalenone results in increased activity of CYP1B1 protein	15157572
C000591741	Firemaster 550	Firemaster 550 results in increased expression of CYP1B1 mRNA	27957850
C028610	flavanone	flavanone binds to and results in decreased activity of CYP1B1 protein	21053930
C043562	flavone	flavone binds to and results in decreased activity of CYP1B1 protein	19563207\|2105393
C043562	flavone	flavone results in increased expression of CYP1B1 mRNA	15890477
C007738	fluoranthene	AHR2 mutant form inhibits the reaction [fluoranthene promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA]]	21600235
C007738	fluoranthene	fluoranthene promotes the reaction [benzo(k)fluoranthene results in increased expression of CYP1B1 mRNA]	21600235
C007738	fluoranthene	fluoranthene results in increased expression of CYP1B1 mRNA	27196671
C007738	fluoranthene	[1-methylanthracene co-treated with fluoranthene co-treated with Benzo(a)pyrene] results in increased expression of CYP1B1 mRNA	29170806
C007738	fluoranthene	[1-methylanthracene co-treated with fluoranthene] results in increased expression of CYP1B1 mRNA	28329830
C007738	fluoranthene	fluoranthene results in increased expression of CYP1B1 mRNA	28329830
C007738	fluoranthene	fluoranthene affects the expression of CYP1B1 mRNA	27099206
C007738	fluoranthene	fluoranthene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]	27099206
C007738	fluoranthene	"[fluoranthene results in decreased activity of CYP1B1 protein] which results in decreased activity of dibenzo(a,l)pyrene"	17961608
C007738	fluoranthene	"[fluoranthene results in decreased activity of CYP1B1 protein] which results in decreased susceptibility to dibenzo(a,l)pyrene"	17961608
C007738	fluoranthene	fluoranthene results in increased expression of CYP1B1 mRNA	25268939
C007738	fluoranthene	TNF protein promotes the reaction [fluoranthene results in increased expression of CYP1B1 mRNA]	25268939
C007738	fluoranthene	fluoranthene results in decreased activity of CYP1B1 protein	17961608
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA	17317680\|2071347
D015073	2-Acetylaminofluorene	TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of CYP1B1 mRNA]	17317680
D019793	Fluorescein	CYP1B1 protein affects the metabolism of Fluorescein analog	20599672
D005485	Flutamide	Flutamide results in increased expression of CYP1B1 mRNA	21525395\|2648540
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP1B1 mRNA	20938992
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYP1B1 gene	20938992
D005557	Formaldehyde	Formaldehyde results in decreased expression of CYP1B1 mRNA	20655997
D005557	Formaldehyde	Formaldehyde results in increased expression of CYP1B1 mRNA	28937961
D005557	Formaldehyde	Formaldehyde results in increased expression of CYP1B1 mRNA	12679049
C007768	formononetin	CYP1B1 protein results in decreased methylation of formononetin	15479032
C007768	formononetin	formononetin results in increased expression of CYP1B1 mRNA	28985473
D005632	Fructose	[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA	26102010
D005632	Fructose	[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein	26102010
D005632	Fructose	tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA]	26102010
D005632	Fructose	tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein]	26102010
C069837	fullerene C60	fullerene C60 results in decreased expression of CYP1B1 mRNA	19167457
C070081	fulvestrant	fulvestrant inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C070081	fulvestrant	fulvestrant inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
C070081	fulvestrant	fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	19460354
C070081	fulvestrant	"fulvestrant promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	21513769
C070081	fulvestrant	fulvestrant promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	28985473
C070081	fulvestrant	fulvestrant results in increased expression of CYP1B1 mRNA	28985473
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP1B1 mRNA]	16280380
C056933	fumonisin B1	fumonisin B1 results in increased expression of CYP1B1 mRNA	24614526
C056933	fumonisin B1	fumonisin B1 results in increased expression of CYP1B1 protein	24614526
C039281	furan	furan results in increased expression of CYP1B1 mRNA	27387713
C037032	galangin	galangin binds to and results in decreased activity of CYP1B1 protein	21053930
C546771	gardiquimod	gardiquimod results in decreased expression of CYP1B1 mRNA	28003376
C546771	gardiquimod	Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in decreased expression of CYP1B1 mRNA]	28003376
D019833	Genistein	CYP1B1 protein affects the chemical synthesis of Genistein	15479032
D019833	Genistein	Genistein binds to and results in decreased activity of CYP1B1 protein	21053930
D019833	Genistein	Genistein results in decreased activity of CYP1B1 protein	15479032
D019833	Genistein	Genistein results in decreased expression of CYP1B1 mRNA	15257099\|1647417
D019833	Genistein	Genistein results in increased expression of CYP1B1 mRNA	16474171\|2352409
D019833	Genistein	triclocarban promotes the reaction [Genistein results in increased expression of CYP1B1 mRNA]	23524099
D019833	Genistein	Genistein results in decreased expression of CYP1B1 mRNA	12075121
C014568	genkwanin	CYP1B1 protein results in increased metabolism of genkwanin	19666078
C014568	genkwanin	[CYP1B1 protein results in increased metabolism of genkwanin] which results in increased chemical synthesis of Apigenin	19666078
D005839	Gentamicins	Gentamicins results in increased expression of CYP1B1 mRNA	18172885
C119493	glucoerucin	glucoerucin results in increased expression of CYP1B1 protein	20833222
C119494	glucoraphanin	glucoraphanin results in increased expression of CYP1B1 protein	20833222
D005947	Glucose	[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein]	28400208
D005947	Glucose	[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein	28400208
D005978	Glutathione	CYP1B1 protein affects the metabolism of [2-hydroxyestradiol co-treated with Glutathione]	14679015
D005978	Glutathione	CYP1B1 protein affects the metabolism of [4-hydroxyestradiol co-treated with Glutathione]	14679015
D005978	Glutathione	[CYP1B1 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac	24246759
C071834	glycidamide	glycidamide results in decreased expression of CYP1B1 mRNA	17822822
D012739	Gonadal Steroid Hormones	CYP1B1 protein polymorphism results in increased metabolism of Gonadal Steroid Hormones	16006997
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CYP1B1 mRNA]	20146248
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	20146248
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins results in decreased expression of CYP1B1 mRNA	20146248
D005937	Glucaric Acid	"[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D005937	Glucaric Acid	"[Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D006063	Chorionic Gonadotropin	Atrazine inhibits the reaction [Chorionic Gonadotropin results in decreased expression of CYP1B1 mRNA]	26923738
D006063	Chorionic Gonadotropin	Chorionic Gonadotropin results in decreased expression of CYP1B1 mRNA	26923738
D006581	Hexachlorobenzene	Hexachlorobenzene results in increased expression of CYP1B1 mRNA	15159207
C000625836	HFPO4 compound	HFPO4 compound results in increased expression of CYP1B1 mRNA	27553808
D017313	Fenretinide	Fenretinide results in increased expression of CYP1B1 mRNA	28973697
D006854	Hydrocortisone	[Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
D006854	Hydrocortisone	Hydrocortisone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 mRNA]	8674863
D006854	Hydrocortisone	Hydrocortisone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
D006854	Hydrocortisone	Hydrocortisone results in decreased expression of CYP1B1 protein	8674863
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of CYP1B1 mRNA	20044591
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of CYP1B1 mRNA	12414654
C031927	hydroquinone	hydroquinone results in increased expression of CYP1B1 mRNA	23416264
C013038	hydroxyhydroquinone	hydroxyhydroquinone results in increased expression of CYP1B1 mRNA	17572062
C026777	ICI 118551	ICI 118551 inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D007069	Ifosfamide	Ifosfamide results in decreased expression of CYP1B1 mRNA	25596134
C031534	imperatorin	"imperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C031534	imperatorin	imperatorin results in decreased activity of CYP1B1 protein	15861043
C031534	imperatorin	imperatorin results in decreased activity of CYP1B1 protein polymorphism	15861043
C041508	indeno(1,2,3-cd)pyrene	"indeno(1,2,3-cd)pyrene results in increased expression of CYP1B1 mRNA"	17253728\|2719667
D007200	Indican	Indican results in increased expression of CYP1B1 mRNA	20000589
D007203	Indigo Carmine	Indigo Carmine results in increased expression of CYP1B1 mRNA	21354474
C027185	indirubin	CYP1B1 protein results in increased metabolism of indirubin	14637189
C027185	indirubin	indirubin results in increased expression of CYP1B1 mRNA	14637189
C027185	indirubin	AHR mutant form inhibits the reaction [indirubin results in increased expression of CYP1B1 protein]	20951181
C027185	indirubin	indirubin results in increased expression of CYP1B1 mRNA	20951181
C027185	indirubin	indirubin results in increased expression of CYP1B1 protein	20951181
C016517	indole-3-carbinol	[indole-3-carbinol co-treated with DDT] results in increased expression of CYP1B1 mRNA	17311112
C016517	indole-3-carbinol	indole-3-carbinol results in increased expression of CYP1B1 mRNA	15890477\|1731111
C016517	indole-3-carbinol	Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA]	22129741
C016517	indole-3-carbinol	indole-3-carbinol affects the expression of CYP1B1 mRNA	21396975
C016517	indole-3-carbinol	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA	22129741
C016517	indole-3-carbinol	indole-3-carbinol results in increased expression of CYP1B1 mRNA	12147290
D007211	Indoles	CYP1B1 protein polymorphism affects the susceptibility to Indoles	16207128
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA"	18061397\|1876217
C075954	indolo(3,2-b)carbazole	"indolo(3,2-b)carbazole results in increased expression of CYP1B1 mRNA"	12419834
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CYP1B1 mRNA	28628672
D007213	Indomethacin	Indomethacin results in increased expression of CYP1B1 mRNA	16184411
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of CYP1B1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 mRNA	15967407
D015056	1-Methyl-3-isobutylxanthine	[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of CYP1B1 protein	15967407
C055542	isoimperatorin	"isoimperatorin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C055542	isoimperatorin	isoimperatorin results in decreased activity of CYP1B1 protein	15861043
C055542	isoimperatorin	isoimperatorin results in decreased activity of CYP1B1 protein polymorphism	15861043
C040920	isoliquiritigenin	"isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	25110319
C040920	isoliquiritigenin	"isoliquiritigenin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 protein]"	25110319
C040920	isoliquiritigenin	isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	25110319
C040920	isoliquiritigenin	isoliquiritigenin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	26134484
C040920	isoliquiritigenin	isoliquiritigenin promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]	26134484
C040920	isoliquiritigenin	isoliquiritigenin results in increased expression of CYP1B1 mRNA	26134484
C015304	isopimpinellin	"isopimpinellin inhibits the reaction [CYP1B1 protein results in increased oxidation of benzo(a)pyrene 7,8-dihydrodiol]"	15861043
C015304	isopimpinellin	isopimpinellin results in decreased activity of CYP1B1 protein	15861043
C015304	isopimpinellin	isopimpinellin results in decreased activity of CYP1B1 protein polymorphism	15861043
C518329	isopropyl-9H-thioxanthen-9-one	isopropyl-9H-thioxanthen-9-one results in increased expression of CYP1B1 mRNA	20558275
D007545	Isoproterenol	Isoproterenol results in increased expression of CYP1B1 mRNA	20003209
D007545	Isoproterenol	Isoproterenol results in increased expression of CYP1B1 mRNA	18725507
C028904	isoproturon	isoproturon results in decreased activity of CYP1B1 protein	18420780
C016527	isoquercitrin	isoquercitrin results in decreased activity of CYP1B1 protein	16271822
D007559	Ivermectin	Ivermectin results in decreased activity of CYP1B1 protein	18420780
C544151	jinfukang	[Cisplatin co-treated with jinfukang] results in increased expression of CYP1B1 mRNA	27392435
C544151	jinfukang	jinfukang results in increased expression of CYP1B1 mRNA	27392435
C098607	JP8 aviation fuel	JP8 aviation fuel affects the expression of CYP1B1 mRNA	17085751
C098607	JP8 aviation fuel	JP8 aviation fuel results in increased expression of CYP1B1 protein	17337753
C006552	kaempferol	kaempferol binds to and results in decreased activity of CYP1B1 protein	21053930
C006552	kaempferol	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]	20846786
C006552	kaempferol	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]	20846786
C006552	kaempferol	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]]	20846786
C006552	kaempferol	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	20846786
C006552	kaempferol	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 enhancer]]	20846786
C006552	kaempferol	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20846786
C006552	kaempferol	kaempferol results in decreased activity of CYP1B1 protein	16271822\|2148247
C006552	kaempferol	kaempferol results in decreased expression of CYP1B1 mRNA	19794518
D007654	Ketoconazole	Ketoconazole results in decreased activity of CYP1B1 protein	14709627
D007654	Ketoconazole	Ketoconazole results in decreased activity of CYP1B1 protein	18420780
C072105	KN 93	KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	18089838
D064747	Lansoprazole	Lansoprazole results in increased expression of CYP1B1 mRNA	12623754
C476223	laquinimod	laquinimod analog results in increased expression of CYP1B1 mRNA	28433708
C008261	lead acetate	lead acetate results in increased expression of CYP1B1 mRNA	22641619
C045463	leflunomide	leflunomide results in increased expression of CYP1B1 mRNA	28988120
C045463	leflunomide	leflunomide results in increased expression of CYP1B1 mRNA	24136188
C052901	lemongrass oil	lemongrass oil affects the expression of CYP1B1 mRNA	25976427
C070840	licochalcone A	licochalcone A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	26134484
C070840	licochalcone A	licochalcone A inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]	26134484
C070840	licochalcone A	licochalcone A results in decreased expression of CYP1B1 mRNA	26134484
D001556	Lindane	Lindane results in decreased expression of CYP1B1 mRNA	17785943
D008044	Linuron	Linuron results in increased expression of CYP1B1 mRNA	16040568
D008095	Lithocholic Acid	Lithocholic Acid results in decreased activity of CYP1B1 protein	18420780
D047311	Luteolin	Luteolin results in decreased activity of CYP1B1 protein	21482471
D047311	Luteolin	Luteolin results in increased expression of CYP1B1 mRNA	23994263
C015329	lycopene	lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]	26775023
C015329	lycopene	lycopene results in decreased activity of CYP1B1 protein	19329757
C119626	M 50367	[M 50367 binds to and results in increased activity of AHR protein] which results in increased activity of CYP1B1 protein	18179178
D017258	Medroxyprogesterone Acetate	CYP1B1 gene polymorphism affects the susceptibility to [Estrogens co-treated with Medroxyprogesterone Acetate]	15987428
D008550	Melatonin	"2,4,3',5'-tetramethoxystilbene inhibits the reaction [CYP1B1 protein results in increased hydroxylation of Melatonin]"	15616152
D008550	Melatonin	CYP1B1 protein results in increased hydroxylation of Melatonin	15616152
D008550	Melatonin	Melatonin results in decreased activity of CYP1B1 protein	19919601
D008617	Mephenytoin	Mephenytoin results in decreased activity of CYP1B1 protein	18420780
C042720	mercuric bromide	mercuric bromide results in increased expression of CYP1B1 mRNA	26272509
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of CYP1B1 mRNA	21435368\|2447260
D008628	Mercury	Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23231920
D008628	Mercury	Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	22579925
D008628	Mercury	Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	23231920
D008628	Mercury	Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	22579925
D008628	Mercury	Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	22579925
D008628	Mercury	Mercury results in increased expression of CYP1B1 protein	22579925\|2323192
D008687	Metformin	Metformin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	25110054
D008687	Metformin	Metformin results in decreased expression of CYP1B1 mRNA	25110054
D008687	Metformin	Metformin results in decreased expression of CYP1B1 protein	25110054
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CYP1B1 mRNA	20938992
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of CYP1B1 gene	20938992
D003915	Dextromethorphan	Dextromethorphan results in decreased activity of CYP1B1 protein	18420780
D008731	Methoxychlor	Methoxychlor results in decreased activity of CYP1B1 protein	18420780
D008731	Methoxychlor	Methoxychlor results in increased expression of CYP1B1 mRNA	21514315
D008731	Methoxychlor	Methoxychlor results in decreased expression of CYP1B1 mRNA	23303685
D008730	Methoxsalen	Methoxsalen results in decreased activity of CYP1B1 protein	18420780
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 mRNA	15746899\|1575058
D008748	Methylcholanthrene	Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]	20348232
D008748	Methylcholanthrene	Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]	20348232
D008748	Methylcholanthrene	Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]	20348232
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of and results in increased activity of CYP1B1 protein	11502733
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 mRNA	11502733\|1210764
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 protein	20093341
D008748	Methylcholanthrene	Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]	20067464
D008748	Methylcholanthrene	CYP1B1 protein results in increased chemical synthesis of Methylcholanthrene metabolite	11922910
D008748	Methylcholanthrene	CYP1B1 protein results in increased metabolism of Methylcholanthrene	11922910
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 mRNA	10402558\|1211777
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 protein	11922910\|2316961
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 mRNA	22940225
D008748	Methylcholanthrene	alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]	27163632
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 mRNA	11323195\|1132896
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP1B1 protein	19889059
D008752	Methylene Chloride	Methylene Chloride results in decreased expression of CYP1B1 mRNA	20359517
D012862	Skatole	Skatole results in increased expression of CYP1B1 mRNA	28571685
C004925	methylmercuric chloride	methylmercuric chloride results in increased expression of CYP1B1 mRNA	23179753\|2627250
C004925	methylmercuric chloride	"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
D008767	Methylmercury Compounds	[Methylmercury Compounds co-treated with Polychlorinated Biphenyls] results in decreased expression of CYP1B1 mRNA	20020106
D008767	Methylmercury Compounds	Methylmercury Compounds results in increased expression of CYP1B1 mRNA	21435368
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of CYP1B1 mRNA"	26251327
D008874	Midazolam	Midazolam results in decreased activity of CYP1B1 protein	18420780
D015735	Mifepristone	Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	9804617
D015735	Mifepristone	Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	17690134
C066851	mithramycin A	mithramycin A results in decreased expression of CYP1B1 protein	25110054
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in increased expression of CYP1B1 mRNA	12706301
D016686	Monocrotaline	[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA	21224054
C517284	monomethyl phthalate	monomethyl phthalate results in increased expression of CYP1B1 mRNA	26924002
D009151	Mustard Gas	Mustard Gas results in increased expression of CYP1B1 mRNA	15674843
C040015	myricetin	myricetin results in decreased activity of CYP1B1 protein	16271822\|2148247
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	25233930
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [TNF protein promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]]	25233930
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of CYP1B1 mRNA"	17450800
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of CYP1B1 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of CYP1B1 mRNA"	25554681
C031721	naphthalene	naphthalene binds to and results in decreased activity of CYP1B1 protein	19563207
C031721	naphthalene	naphthalene results in increased expression of CYP1B1 mRNA	27196671
D009281	Naphthalenes	Naphthalenes results in increased expression of CYP1B1 protein	17337753
C501268	naphtho(2,3-a)pyrene	"naphtho(2,3-a)pyrene results in increased expression of CYP1B1 mRNA"	17253728
C005273	naringenin	naringenin binds to and results in decreased activity of CYP1B1 protein	21053930
C005274	naringin	naringin binds to and results in decreased activity of CYP1B1 protein	21053930
C498045	NCX 4040	NCX 4040 results in decreased activity of CYP1B1 protein	19542225
C028787	N-desmethyltamoxifen	N-desmethyltamoxifen results in decreased activity of CYP1B1 protein	12419016
D009529	Nicardipine	Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]	20067464
D009532	Nickel	Nickel affects the expression of CYP1B1 mRNA	14575637
D009532	Nickel	Nickel results in increased expression of CYP1B1 mRNA	25583101
D009532	Nickel	trichostatin A inhibits the reaction [Nickel affects the expression of CYP1B1 mRNA]	14575637
C022838	nickel chloride	nickel chloride results in decreased expression of CYP1B1 mRNA	12839937\|1464567
C017557	nickel subsulfide	nickel subsulfide results in decreased expression of CYP1B1 mRNA	12760830
C029938	nickel sulfate	nickel sulfate results in decreased expression of CYP1B1 mRNA	22714537
D009543	Nifedipine	Nifedipine results in decreased activity of CYP1B1 protein	18420780
C012655	nimesulide	CYP1B1 protein results in increased glutathionylation of nimesulide	26524229
C062567	N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide	CYP1B1 protein results in increased activity of N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide	15725615
C008661	nobiletin	nobiletin results in increased expression of CYP1B1 mRNA	22743247
C058272	norclozapine	CYP1B1 protein results in increased chemical synthesis of norclozapine	18809730
C010262	norharman	CYP1B1 protein affects the metabolism of [norharman co-treated with aniline]	15279827
C122062	NSC 674495	CYP1B1 protein affects the susceptibility to NSC 674495	17674193
C122062	NSC 674495	Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1B1 mRNA]	11752201
C122062	NSC 674495	NSC 674495 results in increased expression of CYP1B1 mRNA	11752201
C558013	NSC 689534	[NSC 689534 binds to Copper] which results in increased expression of CYP1B1 mRNA	20971185
D019319	Okadaic Acid	Okadaic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10696073
C026209	oltipraz	oltipraz affects the activity of CYP1B1 protein	10775323
C026209	oltipraz	oltipraz metabolite results in decreased activity of CYP1B1 protein	10775323
C026209	oltipraz	oltipraz results in increased expression of CYP1B1 mRNA	15890477
D015525	Fatty Acids, Omega-3	"Fatty Acids, Omega-3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	27492226
D009853	Omeprazole	Omeprazole affects the expression of CYP1B1 mRNA	25826687
D009853	Omeprazole	Omeprazole promotes the reaction [AHR protein binds to CYP1B1 promoter]	21703235
D009853	Omeprazole	Omeprazole promotes the reaction [ARNT protein binds to CYP1B1 promoter]	21703235
D009853	Omeprazole	Omeprazole promotes the reaction [EP300 protein binds to CYP1B1 promoter]	21703235
D009853	Omeprazole	Omeprazole promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]	21703235
D009853	Omeprazole	Omeprazole results in increased expression of CYP1B1 mRNA	12040753\|1262375
D009853	Omeprazole	Omeprazole results in decreased activity of CYP1B1 protein	18420780
D016566	Organoselenium Compounds	Organoselenium Compounds binds to and results in decreased activity of CYP1B1 protein	21732699
D010069	Oxadiazoles	[Oxadiazoles analog co-treated with FGF2 protein] results in increased expression of CYP1B1 mRNA	23212921
C030110	oxaliplatin	[oxaliplatin co-treated with Topotecan] results in increased expression of CYP1B1 mRNA	25729387
C030110	oxaliplatin	oxaliplatin results in increased expression of CYP1B1 mRNA	25729387
D010078	Oxazines	CYP1B1 protein affects the metabolism of Oxazines analog	20599672
D010100	Oxygen	[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein]	28400208
D010100	Oxygen	[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein	28400208
D010100	Oxygen	Oxygen deficiency inhibits the reaction [AHR protein binds to CYP1B1 promoter]	24355420
D010100	Oxygen	Oxygen deficiency results in decreased expression of CYP1B1 mRNA	25596134
D010100	Oxygen	[Benzo(a)pyrene co-treated with Oxygen] affects the expression of CYP1B1 protein	24657529
D010126	Ozone	AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 mRNA]	19536146
D010126	Ozone	AHR protein affects the reaction [Ozone results in increased expression of CYP1B1 protein]	19536146
D010126	Ozone	Ozone results in increased expression of CYP1B1 mRNA	19536146
D010126	Ozone	Ozone results in increased expression of CYP1B1 protein	19536146
D000073878	Palm Oil	Palm Oil results in decreased expression of CYP1B1 mRNA	18042831
C496932	panobinostat	"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C496932	panobinostat	panobinostat results in increased expression of CYP1B1 mRNA	26272509
D010269	Paraquat	Paraquat affects the expression of CYP1B1 mRNA	25064622
D010269	Paraquat	"[17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA"	17275934
C084656	paricalcitol	[Phosphorus co-treated with paricalcitol] results in decreased expression of CYP1B1 mRNA	17715259
D052638	Particulate Matter	Particulate Matter analog results in increased expression of CYP1B1 mRNA	27216425
D052638	Particulate Matter	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]	28655636
D052638	Particulate Matter	Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]	21703343
D052638	Particulate Matter	Particulate Matter analog results in increased expression of CYP1B1 mRNA	12396873\|2447261
D052638	Particulate Matter	Particulate Matter analog results in increased expression of CYP1B1 protein	12396873
D052638	Particulate Matter	"[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP1B1 mRNA"	17612574
D052638	Particulate Matter	Particulate Matter inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	19835593
D052638	Particulate Matter	Particulate Matter results in decreased expression of CYP1B1 mRNA	19835593
D052638	Particulate Matter	Particulate Matter results in decreased expression of CYP1B1 protein	19835593
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP1B1 mRNA	15046786\|2170334
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP1B1 protein	22178795
D052638	Particulate Matter	[titanium dioxide co-treated with Particulate Matter] results in decreased expression of CYP1B1 mRNA	19835593
D052638	Particulate Matter	Particulate Matter results in decreased expression of CYP1B1 protein	23451061
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP1B1 mRNA	24365139
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP1B1 protein	21371539\|2345106
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP1B1 mRNA	22352393\|2421647
C410127	PCB 180	"[2,4,4'-trichlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,3',4,4',5-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of CYP1B1 mRNA"	15808785
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether analog results in increased expression of CYP1B1 mRNA	19095052
C086401	pentabromodiphenyl ether	pentabromodiphenyl ether results in increased expression of CYP1B1 mRNA	26705709
D010578	Petroleum	Petroleum results in increased expression of CYP1B1 mRNA	25208076
D015232	Dinoprostone	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D015232	Dinoprostone	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D015232	Dinoprostone	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D015232	Dinoprostone	AH 23848 inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	AH 23848 inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D015232	Dinoprostone	Dinoprostone results in increased expression of CYP1B1 mRNA	20093341
D015232	Dinoprostone	Dinoprostone results in increased expression of CYP1B1 protein	20093341
D015232	Dinoprostone	fulvestrant inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	fulvestrant inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D015232	Dinoprostone	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
D015232	Dinoprostone	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 mRNA]	20093341
D015232	Dinoprostone	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Dinoprostone results in increased expression of CYP1B1 protein]	20093341
C031181	phenanthrene	CYP1B1 gene polymorphism results in decreased metabolism of phenanthrene	17035385
C031181	phenanthrene	CYP1B1 protein results in increased metabolism of and results in increased activity of phenanthrene	19766613
C031181	phenanthrene	CYP1B1 protein results in increased oxidation of phenanthrene	27137136
C031181	phenanthrene	[CYP1B1 protein results in increased oxidation of phenanthrene] which results in increased abundance of 9-phenanthrol	27137136
C031181	phenanthrene	phenanthrene binds to and results in decreased activity of CYP1B1 protein	19563207
C031181	phenanthrene	"[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA"	15566942
D010616	Phenanthrenes	Phenanthrenes analog results in increased expression of CYP1B1 protein	19365803
D010634	Phenobarbital	Phenobarbital results in increased expression of CYP1B1 mRNA	23273579
D010662	Phenylmercuric Acetate	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
D010662	Phenylmercuric Acetate	Phenylmercuric Acetate results in increased expression of CYP1B1 mRNA	26272509
D010672	Phenytoin	[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA	21224054
D010758	Phosphorus	[Phosphorus co-treated with paricalcitol] results in decreased expression of CYP1B1 mRNA	17715259
C121565	pifithrin	pifithrin results in decreased activity of CYP1B1 protein	16258175
C121565	pifithrin	pifithrin results in increased expression of CYP1B1 mRNA	16258175
D010882	Piperonyl Butoxide	Piperonyl Butoxide results in increased expression of CYP1B1 mRNA	10402558
C006253	pirinixic acid	pirinixic acid results in decreased expression of CYP1B1 mRNA	16985257
D010936	Plant Extracts	"3',4'-dimethoxyflavone inhibits the reaction [Plant Extracts results in increased expression of CYP1B1 mRNA]"	19794518
D010936	Plant Extracts	Plant Extracts inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]	26134484
D010936	Plant Extracts	Plant Extracts promotes the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of CYP1B1 mRNA]	26134484
D010936	Plant Extracts	Plant Extracts results in decreased expression of CYP1B1 mRNA	26134484
D010936	Plant Extracts	Plant Extracts results in increased expression of CYP1B1 mRNA	18061397\|1979451
D010936	Plant Extracts	"[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D010936	Plant Extracts	"[Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D010936	Plant Extracts	Plant Extracts results in decreased activity of CYP1B1 protein	19329757
D010936	Plant Extracts	"[resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
D028321	Plant Preparations	CYP1B1 gene polymorphism affects the susceptibility to Plant Preparations	17602170
D028321	Plant Preparations	Plant Preparations results in increased expression of CYP1B1 mRNA	24973489
D011078	Polychlorinated Biphenyls	Polychlorinated Biphenyls analog results in decreased expression of CYP1B1 mRNA	16474171
D011078	Polychlorinated Biphenyls	Polychlorinated Biphenyls analog results in increased expression of CYP1B1 mRNA	16474171
D011078	Polychlorinated Biphenyls	[Methylmercury Compounds co-treated with Polychlorinated Biphenyls] results in decreased expression of CYP1B1 mRNA	20020106
D011078	Polychlorinated Biphenyls	"[Polychlorinated Biphenyls co-treated with Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1B1 mRNA"	15858227
D000072317	Polychlorinated Dibenzodioxins	"[Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1B1 mRNA"	17850846
D000072317	Polychlorinated Dibenzodioxins	Polychlorinated Dibenzodioxins results in increased expression of CYP1B1 mRNA	19358281
D000072317	Polychlorinated Dibenzodioxins	Polychlorinated Dibenzodioxins results in increased expression of CYP1B1 mRNA	23674508
D000072317	Polychlorinated Dibenzodioxins	"[Polychlorinated Biphenyls co-treated with Polychlorinated Dibenzodioxins co-treated with Dibenzofurans, Polychlorinated] results in increased expression of CYP1B1 mRNA"	15858227
D011084	Polycyclic Aromatic Hydrocarbons	CYP1B1 protein affects the metabolism of Polycyclic Aromatic Hydrocarbons	15122594
D011084	Polycyclic Aromatic Hydrocarbons	Polycyclic Aromatic Hydrocarbons results in decreased expression of CYP1B1 mRNA	15471096
D011084	Polycyclic Aromatic Hydrocarbons	Polycyclic Aromatic Hydrocarbons results in increased expression of CYP1B1 mRNA	15278913\|1547109
D011084	Polycyclic Aromatic Hydrocarbons	Polycyclic Aromatic Hydrocarbons results in increased expression of CYP1B1 protein	15720126
C027373	potassium chromate(VI)	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CYP1B1 mRNA	22079256
C027373	potassium chromate(VI)	potassium chromate(VI) results in decreased expression of CYP1B1 mRNA	22079256\|2271453
D011192	Potassium Dichromate	Potassium Dichromate results in decreased expression of CYP1B1 mRNA	23608068
D017035	Pravastatin	Pravastatin results in increased expression of CYP1B1 mRNA	27225895
D017035	Pravastatin	Pravastatin affects the expression of CYP1B1 mRNA	27225895
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]	28428138
D011319	Primaquine	Primaquine results in increased expression of CYP1B1 mRNA	12623754
C045362	prochloraz	prochloraz results in increased expression of CYP1B1 mRNA	20035023
C045362	prochloraz	prochloraz results in increased expression of CYP1B1 protein	20035023
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in increased expression of CYP1B1 mRNA	20660070
D011374	Progesterone	Progesterone results in decreased expression of CYP1B1 mRNA	18037150
D011374	Progesterone	[Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
D011374	Progesterone	Progesterone inhibits the reaction [benz(a)anthracene results in increased expression of CYP1B1 protein]	8674863
D011374	Progesterone	Progesterone results in decreased expression of CYP1B1 protein	8674863
D011374	Progesterone	Progesterone results in increased expression of CYP1B1 mRNA	20726854
D011433	Propranolol	Propranolol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D011441	Propylthiouracil	Propylthiouracil results in decreased expression of CYP1B1 mRNA	24780913
D047428	Protein Kinase Inhibitors	Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in decreased expression of CYP1B1 mRNA]	28003376
C511975	purpurin	purpurin results in decreased activity of CYP1B1 protein	12379470
C511975	purpurin	purpurin results in increased expression of CYP1B1 mRNA	11502733
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of CYP1B1 mRNA	27029645
C030984	pyrene	CYP1B1 protein results in increased hydroxylation of pyrene	15016593
C030984	pyrene	"[phenanthrene co-treated with pyrene co-treated with Benzo(a)pyrene co-treated with benzo(k)fluoranthene co-treated with dibenzo(a,l)pyrene co-treated with benzo(b)fluoranthene] results in increased expression of CYP1B1 mRNA"	15566942
C030984	pyrene	pyrene binds to and results in decreased activity of CYP1B1 protein	19563207
C030984	pyrene	pyrene results in increased expression of CYP1B1 protein	19365803
D011763	Pyrrolizidine Alkaloids	Pyrrolizidine Alkaloids results in increased expression of CYP1B1 mRNA	26100227
D011794	Quercetin	Quercetin binds to and results in decreased activity of CYP1B1 protein	21053930
D011794	Quercetin	Quercetin results in decreased activity of CYP1B1 protein	16271822\|2148247
D011794	Quercetin	Quercetin results in decreased expression of CYP1B1 mRNA	17637178
D011794	Quercetin	Quercetin results in increased expression of CYP1B1 mRNA	19794518\|2125695
D011794	Quercetin	"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of and results in increased activity of CYP1B1 protein]"	22044346
D011794	Quercetin	"Quercetin inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	22044346
D011794	Quercetin	Quercetin results in decreased activity of CYP1B1 protein	18420780
D011794	Quercetin	Quercetin results in increased expression of CYP1B1 mRNA	22334599
D011794	Quercetin	Quercetin affects the expression of CYP1B1 mRNA	18178720
C012526	quercitrin	quercitrin results in decreased activity of CYP1B1 protein	16271822
D011802	Quinidine	Quinidine results in decreased activity of CYP1B1 protein	18420780
C502851	quinocetone	quinocetone results in decreased expression of CYP1B1 mRNA	27046791
D011806	Quinolinium Compounds	Quinolinium Compounds results in increased expression of CYP1B1 mRNA	23000282
C059514	resveratrol	resveratrol results in decreased activity of CYP1B1 mRNA	11100935
C059514	resveratrol	resveratrol results in decreased expression of CYP1B1 mRNA	11100935
C059514	resveratrol	[Coumestrol co-treated with resveratrol] results in increased expression of CYP1B1 mRNA	19167446
C059514	resveratrol	CYP1B1 protein affects the metabolism of resveratrol	15276085
C059514	resveratrol	resveratrol affects the expression of CYP1B1 protein	15893423
C059514	resveratrol	resveratrol binds to and results in decreased activity of CYP1B1 protein	19563207
C059514	resveratrol	resveratrol inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1B1 protein]	16484233
C059514	resveratrol	resveratrol inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	11279601\|1516214
C059514	resveratrol	resveratrol inhibits the reaction [CYP1B1 protein affects the chemical synthesis of 4-hydroxyestradiol]	15142886
C059514	resveratrol	resveratrol inhibits the reaction [CYP1B1 protein affects the metabolism of Estradiol]	15142886
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]	19376845\|2084678
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]	20846786
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]]	19376845\|2084678
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	20846786
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 enhancer]]	20846786
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	15142886
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	11279601\|1514288
C059514	resveratrol	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	19138946
C059514	resveratrol	resveratrol results in decreased activity of CYP1B1 protein	11714871
C059514	resveratrol	resveratrol results in decreased expression of CYP1B1	15316568
C059514	resveratrol	resveratrol results in decreased expression of CYP1B1 mRNA	11279601\|1499033
C059514	resveratrol	resveratrol results in decreased expression of CYP1B1 protein	15182955
C059514	resveratrol	"[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
C059514	resveratrol	"[Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
C059514	resveratrol	[resveratrol co-treated with Benzo(a)pyrene] results in decreased expression of CYP1B1 protein	18694800
C059514	resveratrol	"[resveratrol co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	20103723
C059514	resveratrol	resveratrol results in decreased activity of CYP1B1 protein	18420780\|1932975
D012293	Rifampin	[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1B1 mRNA	29162470
D012293	Rifampin	[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA	21224054
C089730	rosiglitazone	rosiglitazone results in increased expression of CYP1B1 mRNA	25572481\|2559613
C028632	rutecarpine	rutecarpine analog binds to and results in decreased activity of CYP1B1 protein	12852960
D012431	Rutin	Rutin results in decreased activity of CYP1B1 protein	16271822
C031060	salicylamide	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	14729655
C005705	sanguinarine	sanguinarine results in increased activity of CYP1B1 protein	15993743
C005705	sanguinarine	sanguinarine results in increased expression of CYP1B1 mRNA	15993743
C458179	scutellarein	CYP1B1 protein affects the metabolism of scutellarein	19666078
C458179	scutellarein	[CYP1B1 protein affects the metabolism of scutellarein] which results in increased chemical synthesis of 6-hydroxyluteolin	19666078
C458179	scutellarein	scutellarein results in decreased activity of CYP1B1 protein	21482471
C116890	Semaxinib	Semaxinib results in increased expression of CYP1B1 mRNA	28424418
C009237	senecionine	senecionine results in increased expression of CYP1B1 mRNA	26100227
C120148	SIB 1893	SIB 1893 results in decreased activity of CYP1B1 protein	15193955
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of CYP1B1 mRNA	23806026\|2589566
C059295	sinensetin	CYP1B1 protein results in increased metabolism of sinensetin	19666078
D012906	Smoke	Smoke results in increased expression of CYP1B1 mRNA	20015843\|2109522
C009277	sodium arsenate	sodium arsenate results in decreased expression of CYP1B1 mRNA	11353140
C017947	sodium arsenite	sodium arsenite affects the methylation of CYP1B1 gene	28589171
C017947	sodium arsenite	sodium arsenite results in decreased expression of CYP1B1 mRNA	12727804\|2271453
C017947	sodium arsenite	sodium arsenite results in decreased expression of CYP1B1 mRNA	11353140
C017947	sodium arsenite	sodium arsenite results in increased expression of CYP1B1 mRNA	25065748
C016104	sodium bichromate	sodium bichromate results in decreased expression of CYP1B1 mRNA	12760830
C016104	sodium bichromate	Benzo(a)pyrene promotes the reaction [sodium bichromate results in increased expression of CYP1B1 mRNA]	22613061
C016104	sodium bichromate	sodium bichromate results in increased expression of CYP1B1 mRNA	22613061
D053260	Soot	Soot results in increased expression of CYP1B1 mRNA	18684396
D053260	Soot	Soot affects the expression of CYP1B1 mRNA	19165387
C075117	squalestatin 1	squalestatin 1 affects the expression of CYP1B1 mRNA	27225895
C075117	squalestatin 1	squalestatin 1 results in decreased expression of CYP1B1 mRNA	27225895
C539817	S-sulindac	"S-sulindac inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]"	19276279
C539817	S-sulindac	S-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19276279
C539817	S-sulindac	S-sulindac results in decreased activity of CYP1B1 protein	19276279
C552240	StemRegenin 1	StemRegenin 1 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20688981
C552240	StemRegenin 1	StemRegenin 1 results in decreased expression of CYP1B1 mRNA	20688981
C012042	steviol	steviol results in increased expression of CYP1B1 mRNA	28887089
C012043	stevioside	stevioside results in increased expression of CYP1B1 mRNA	28887089
D013267	Stilbenes	Stilbenes analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	18449500
C458525	STO 609	STO 609 results in increased expression of CYP1B1 mRNA	18755850
C016766	sulforafan	sulforafan results in increased expression of CYP1B1 mRNA	26833863
C016766	sulforafan	sulforafan results in increased expression of CYP1B1 protein	18823965
D013467	Sulindac	Sulindac results in increased expression of CYP1B1 mRNA	17985343
D013467	Sulindac	Sulindac results in increased activity of CYP1B1 protein	16531450
D013467	Sulindac	Sulindac results in increased expression of CYP1B1 mRNA	16531450
C025462	sulindac sulfide	sulindac sulfide results in increased expression of CYP1B1 mRNA	12734198\|1798534
C473478	sunitinib	sunitinib results in increased expression of CYP1B1 mRNA	26797788
C074269	Sunphenon	"Sunphenon promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP1B1 mRNA]"	24378064
D013498	Suramin	Suramin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22167199
D013629	Tamoxifen	Tamoxifen results in decreased activity of CYP1B1 protein	12419016
D013629	Tamoxifen	Tamoxifen results in increased expression of CYP1B1 protein	19812351
D013629	Tamoxifen	Tamoxifen results in decreased activity of CYP1B1 protein	18420780
D013739	Testosterone	Testosterone results in decreased activity of CYP1B1 protein	18420780
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased expression of CYP1B1 mRNA	25172293
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in increased expression of CYP1B1 mRNA	26988606\|2830066
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	19167471
D013749	Tetrachlorodibenzodioxin	AHRRB protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19494032
D013749	Tetrachlorodibenzodioxin	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19403181
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	15716485\|1644369
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP1B1 mRNA	26043675
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the reaction [LHB protein affects the expression of CYP1B1 mRNA]	26043675
D013749	Tetrachlorodibenzodioxin	"2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	19463925
D013749	Tetrachlorodibenzodioxin	"2,2',4,6'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]"	19463925
D013749	Tetrachlorodibenzodioxin	"2-((2,6-dichlorophenyl)amino)benzeneacetic acid 4-(3H-1,2-dithiol-3-thione-5-yl)phenyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	19276279
D013749	Tetrachlorodibenzodioxin	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9495809
D013749	Tetrachlorodibenzodioxin	"2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	16120791
D013749	Tetrachlorodibenzodioxin	"2,4,3',5'-tetramethoxystilbene inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]"	16120791
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23625689
D013749	Tetrachlorodibenzodioxin	"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]"	20846786
D013749	Tetrachlorodibenzodioxin	"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]]"	20846786
D013749	Tetrachlorodibenzodioxin	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]"	17183067
D013749	Tetrachlorodibenzodioxin	"3-(3-methoxyphenyl)-N-(3,4,5-trimethoxyphenyl)acrylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	17183067
D013749	Tetrachlorodibenzodioxin	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20823264
D013749	Tetrachlorodibenzodioxin	5-androstene-16-fluoro-17-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12097275
D013749	Tetrachlorodibenzodioxin	afimoxifene inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	19460354
D013749	Tetrachlorodibenzodioxin	AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	24299737
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	20171976
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20171976
D013749	Tetrachlorodibenzodioxin	AHR protein polymorphism affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	27535091
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 gene]]	19574409
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20846786
D013749	Tetrachlorodibenzodioxin	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	15075337\|1918226
D013749	Tetrachlorodibenzodioxin	ARNT gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [AHR protein binds to CYP1B1 promoter]]]	24299737
D013749	Tetrachlorodibenzodioxin	ARNT gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	24299737
D013749	Tetrachlorodibenzodioxin	ARNT protein affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [BRCA1 protein binds to CYP1B1 promoter]]	16567799
D013749	Tetrachlorodibenzodioxin	Azacitidine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12927368
D013749	Tetrachlorodibenzodioxin	"benzo(a)pyrene 7,8-dihydrodiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	21028851
D013749	Tetrachlorodibenzodioxin	BRCA1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	16567799
D013749	Tetrachlorodibenzodioxin	Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	16237193
D013749	Tetrachlorodibenzodioxin	calyculin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10696073
D013749	Tetrachlorodibenzodioxin	CL 075 promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	27783115
D013749	Tetrachlorodibenzodioxin	Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19018768
D013749	Tetrachlorodibenzodioxin	Curcumin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	19018768
D013749	Tetrachlorodibenzodioxin	Cycloheximide inhibits the reaction [TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	9145908
D013749	Tetrachlorodibenzodioxin	decitabine promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20631054
D013749	Tetrachlorodibenzodioxin	EP300 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	18842620
D013749	Tetrachlorodibenzodioxin	ESR1 protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 gene]]	19574409
D013749	Tetrachlorodibenzodioxin	ESR1 protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19460354\|1957440
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Estradiol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	15837795
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [NCOA3 protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	15157572
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19619570
D013749	Tetrachlorodibenzodioxin	Estradiol promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	19619570
D013749	Tetrachlorodibenzodioxin	fulvestrant inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	19460354
D013749	Tetrachlorodibenzodioxin	fulvestrant promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	28985473
D013749	Tetrachlorodibenzodioxin	isoliquiritigenin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	25110319
D013749	Tetrachlorodibenzodioxin	isoliquiritigenin promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	26134484
D013749	Tetrachlorodibenzodioxin	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]	20846786
D013749	Tetrachlorodibenzodioxin	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]	20846786
D013749	Tetrachlorodibenzodioxin	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]]	20846786
D013749	Tetrachlorodibenzodioxin	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	20846786
D013749	Tetrachlorodibenzodioxin	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 enhancer]]	20846786
D013749	Tetrachlorodibenzodioxin	kaempferol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20846786
D013749	Tetrachlorodibenzodioxin	KN 93 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	18089838
D013749	Tetrachlorodibenzodioxin	licochalcone A inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	26134484
D013749	Tetrachlorodibenzodioxin	Metformin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	25110054
D013749	Tetrachlorodibenzodioxin	NCOA2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	18842620
D013749	Tetrachlorodibenzodioxin	Okadaic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10696073
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]]	19376845\|2084678
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]]	20846786
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]]	19376845\|2084678
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	20846786
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 enhancer]]	20846786
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	15142886
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	11279601\|1514288
D013749	Tetrachlorodibenzodioxin	resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	19138946
D013749	Tetrachlorodibenzodioxin	salicylamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	14729655
D013749	Tetrachlorodibenzodioxin	[SP1 protein binds to CYP1B1 enhancer] promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12801909\|1280190
D013749	Tetrachlorodibenzodioxin	S-sulindac inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19276279
D013749	Tetrachlorodibenzodioxin	StemRegenin 1 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20688981
D013749	Tetrachlorodibenzodioxin	Stilbenes analog inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	18449500
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP1B1 mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the localization of CYP1B1 protein	19138946
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	14729655\|2783716
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with AHR mRNA] affects the expression of CYP1B1 mRNA	20619336
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in increased expression of CYP1B1 mRNA	19684285
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1B1 mRNA	29162470
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR gene SNP results in increased expression of CYP1B1 mRNA]	20817071
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1B1 enhancer]	12801909
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]	17785579\|1884262
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 gene]	19574409\|2480634
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]	19460354\|2081707
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein SNP binds to CYP1B1 promoter]	20817071
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR results in increased expression of CYP1B1 mRNA]	20817071
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHRR protein binds to CYP1B1 gene]	24806346
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 enhancer]	19376845\|2084678
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 gene]	24806346
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ARNT protein binds to CYP1B1 promoter]	16567799\|2084678
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [BRCA1 protein binds to CYP1B1 promoter]	16567799
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]	9706865
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [EP300 protein binds to CYP1B1 enhancer]	18842620
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [EP300 protein binds to CYP1B1 promoter]	18842620\|2170323
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 enhancer]	20846786
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 gene]	19574409
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [ESR1 protein binds to CYP1B1 promoter]	19460354\|2207132
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [AHR protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [ARNT protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [Estradiol promotes the reaction [ESR1 protein binds to CYP1B1 promoter]]	24299737
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [NCOA1 protein binds to CYP1B1 enhancer]	18842620
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [NCOA1 protein binds to CYP1B1 promoter]	18842620\|2170323
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [NCOA2 protein binds to CYP1B1 enhancer]	18842620
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [NCOA2 protein binds to CYP1B1 promoter]	18842620
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [NCOA3 protein binds to CYP1B1 promoter]	24299737
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [SMARCA4 protein binds to CYP1B1 enhancer]	18842620
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [SMARCA4 protein binds to CYP1B1 promoter]	18842620
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP1B1 mRNA	17101203\|2226271
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein	14637189\|1515757
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1	27697457
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	10067811\|1035777
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA polymorphism	15596250
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein	10357772\|1145214
D013749	Tetrachlorodibenzodioxin	Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	11728381
D013749	Tetrachlorodibenzodioxin	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]	9706865
D013749	Tetrachlorodibenzodioxin	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	9706865
D013749	Tetrachlorodibenzodioxin	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9706865
D013749	Tetrachlorodibenzodioxin	TGFB1 protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9145908\|9405238
D013749	Tetrachlorodibenzodioxin	TIPARP mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	24806346
D013749	Tetrachlorodibenzodioxin	[Tretinoin co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA	21376804
D013749	Tetrachlorodibenzodioxin	Tretinoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	15075337
D013749	Tetrachlorodibenzodioxin	trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12927368
D013749	Tetrachlorodibenzodioxin	Zearalenone promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	15157572
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	24013123
D013749	Tetrachlorodibenzodioxin	3'-methoxy-4'-nitroflavone inhibits the reaction [AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]]	15183014
D013749	Tetrachlorodibenzodioxin	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19782052
D013749	Tetrachlorodibenzodioxin	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	15050417\|2401312
D013749	Tetrachlorodibenzodioxin	AHR affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9377560
D013749	Tetrachlorodibenzodioxin	AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	16984957
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	22262711
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	9855628
D013749	Tetrachlorodibenzodioxin	AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP1B1 mRNA]	14728982
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	15183014
D013749	Tetrachlorodibenzodioxin	AHRR gene mutant form promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	24806346
D013749	Tetrachlorodibenzodioxin	ARNT affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	20935161
D013749	Tetrachlorodibenzodioxin	Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19782052
D013749	Tetrachlorodibenzodioxin	chelerythrine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10037446
D013749	Tetrachlorodibenzodioxin	chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	10037446
D013749	Tetrachlorodibenzodioxin	"Dehydroepiandrosterone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10497882
D013749	Tetrachlorodibenzodioxin	"Fatty Acids, Omega-3 inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	27492226
D013749	Tetrachlorodibenzodioxin	Mercury affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23231920
D013749	Tetrachlorodibenzodioxin	Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	22579925
D013749	Tetrachlorodibenzodioxin	Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	23231920
D013749	Tetrachlorodibenzodioxin	Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	22579925
D013749	Tetrachlorodibenzodioxin	Mercury promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	22579925
D013749	Tetrachlorodibenzodioxin	PER1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19038280
D013749	Tetrachlorodibenzodioxin	PER2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19038280
D013749	Tetrachlorodibenzodioxin	PLA2G4A protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	29043426
D013749	Tetrachlorodibenzodioxin	"PRKCB protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10037446
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP1B1 mRNA	15037607\|2157046
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of CYP1B1 mRNA	16214954
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	22483799\|2783716
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with AHR protein] results in increased expression of CYP1B1 mRNA	20817071
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Dietary Fats] results in increased expression of CYP1B1 mRNA	20435547
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of CYP1B1 mRNA	25975270
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of CYP1B1 protein	25975270
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR gene SNP results in increased expression of CYP1B1 mRNA]	20817071
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 enhancer]	20116417\|9478971
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 gene]	20819909\|2176248
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1B1 promoter]	19282623\|1965492
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein results in increased expression of CYP1B1 mRNA]	19782052
D013749	Tetrachlorodibenzodioxin	"Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446\|1049788
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP1B1 mRNA	14728982
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein	23231920\|2342371
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1	24213002
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	10037446\|1049788
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein	10037446\|1005158
D013749	Tetrachlorodibenzodioxin	"Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10037446
D013749	Tetrachlorodibenzodioxin	Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10037446
D013749	Tetrachlorodibenzodioxin	TIPARP protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	25975270
D013749	Tetrachlorodibenzodioxin	trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]	26042454
D013749	Tetrachlorodibenzodioxin	trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	26042454\|2614406
D013749	Tetrachlorodibenzodioxin	trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	26144063
D013749	Tetrachlorodibenzodioxin	Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]	23423713
D013749	Tetrachlorodibenzodioxin	Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23423713
D013749	Tetrachlorodibenzodioxin	Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]	23423713
D013749	Tetrachlorodibenzodioxin	Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23423713
D013749	Tetrachlorodibenzodioxin	WNT3A protein promotes the reaction [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA]	21602191
D013749	Tetrachlorodibenzodioxin	WNT3A protein promotes the reaction [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 protein]	21602191
D013749	Tetrachlorodibenzodioxin	"[17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA"	17275934
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	17275934
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	20153503
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein	20153503
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1	15993909
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23196670
D013749	Tetrachlorodibenzodioxin	AHR gene mutant form inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23859880\|2759092
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	19497421\|2319667
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	25233930
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]]	25233930
D013749	Tetrachlorodibenzodioxin	ARNT protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23196670
D013749	Tetrachlorodibenzodioxin	Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9804617
D013749	Tetrachlorodibenzodioxin	Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	9804617
D013749	Tetrachlorodibenzodioxin	Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	17690134
D013749	Tetrachlorodibenzodioxin	"Drugs, Chinese Herbal promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]"	16901605
D013749	Tetrachlorodibenzodioxin	Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	9804617
D013749	Tetrachlorodibenzodioxin	Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	17690134
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP1B1 mRNA	22298810\|2834157
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA	21602191
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 protein	21602191
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1B1 enhancer]	12859982
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	16198082
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein	19497421\|7588239
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	10568693\|1091096
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein	16237193\|1755791
D013749	Tetrachlorodibenzodioxin	TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	17557910
D013749	Tetrachlorodibenzodioxin	TNF protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	17557910\|2523393
D013749	Tetrachlorodibenzodioxin	AHRR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	28681081
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA	28681081
D013752	Tetracycline	Tetracycline affects the expression of CYP1B1 mRNA	25064622
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	11728381
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]	9706865
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]	9706865
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	9706865
D013755	Tetradecanoylphorbol Acetate	chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]	10037446
D013755	Tetradecanoylphorbol Acetate	"Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]"	10037446
D013755	Tetradecanoylphorbol Acetate	"Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]"	10037446
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	10037446
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in decreased expression of CYP1B1 mRNA	10037446
C096277	tetrahydrocurcumin	tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 mRNA]	26102010
C096277	tetrahydrocurcumin	tetrahydrocurcumin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of CYP1B1 protein]	26102010
D013853	Thioacetamide	Thioacetamide affects the expression of CYP1B1 mRNA	25064622
C009495	titanium dioxide	[titanium dioxide co-treated with Particulate Matter] results in decreased expression of CYP1B1 mRNA	19835593
C009495	titanium dioxide	titanium dioxide results in decreased expression of CYP1B1 mRNA	23557971
D014028	Tobacco Smoke Pollution	CYP1B1 results in decreased susceptibility to Tobacco Smoke Pollution	27576004
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of CYP1B1 mRNA	27576004
D014028	Tobacco Smoke Pollution	AHR protein promotes the reaction [Tobacco Smoke Pollution results in increased expression of CYP1B1 mRNA]	27450509
D014028	Tobacco Smoke Pollution	[[Doxycycline results in increased expression of AHR protein] which co-treated with Tobacco Smoke Pollution] results in increased expression of CYP1B1 mRNA	22273977
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of CYP1B1 mRNA	16996243\|1868439
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of CYP1B1 protein	16996243
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased methylation of CYP1B1 promoter	25214829
D014028	Tobacco Smoke Pollution	[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of CYP1B1 mRNA	24096154
D014028	Tobacco Smoke Pollution	NFE2L2 protein inhibits the reaction [Tobacco Smoke Pollution affects the expression of CYP1B1 mRNA]	20133372
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution affects the expression of CYP1B1 mRNA	20133372
D014028	Tobacco Smoke Pollution	[Vehicle Emissions analog co-treated with Coal Tar analog co-treated with Tobacco Smoke Pollution analog] results in increased expression of CYP1B1 mRNA	22935520\|2327456
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of CYP1B1 mRNA	22266391
D014050	Toluene	Toluene results in decreased expression of CYP1B1 mRNA	20359517
D019772	Topotecan	[oxaliplatin co-treated with Topotecan] results in increased expression of CYP1B1 mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of CYP1B1 mRNA	25729387
C012293	tranilast	tranilast affects the expression of CYP1B1 mRNA	25826687
C507866	trans-1,2-dihydro-1,2-naphthalenediol	"CYP1B1 protein results in increased abundance of trans-1,2-dihydro-1,2-naphthalenediol"	16243959
D014212	Tretinoin	[Tretinoin co-treated with arsenic trioxide] results in decreased expression of CYP1B1 mRNA	15894607
D014212	Tretinoin	[Tretinoin co-treated with Tetrachlorodibenzodioxin] results in increased expression of CYP1B1 mRNA	21376804
D014212	Tretinoin	Tretinoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	15075337
D014212	Tretinoin	Tretinoin results in increased expression of CYP1B1 mRNA	12870655\|1698516
D014212	Tretinoin	Tretinoin results in decreased activity of CYP1B1 protein	18420780
C032910	triadimefon	triadimefon results in increased expression of CYP1B1 mRNA	26705709
D014241	Trichloroethylene	Trichloroethylene results in decreased expression of CYP1B1 mRNA	20359517
D014241	Trichloroethylene	Trichloroethylene results in increased methylation of CYP1B1 gene	27618143
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C012589	trichostatin A	trichostatin A inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	15713371
C012589	trichostatin A	trichostatin A inhibits the reaction [Nickel affects the expression of CYP1B1 mRNA]	14575637
C012589	trichostatin A	trichostatin A promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	12927368
C012589	trichostatin A	trichostatin A results in increased expression of CYP1B1 mRNA	12927368\|2493525
C009540	triclocarban	ESR1 protein affects the reaction [triclocarban results in increased expression of CYP1B1 mRNA]	22761658
C009540	triclocarban	triclocarban promotes the reaction [bisphenol A results in increased expression of CYP1B1 mRNA]	23524099
C009540	triclocarban	triclocarban promotes the reaction [Genistein results in increased expression of CYP1B1 mRNA]	23524099
C009540	triclocarban	triclocarban results in increased expression of CYP1B1 mRNA	22761658
C009540	triclocarban	triclocarban results in increased expression of CYP1B1 mRNA	22761658
C052920	trimethylarsine oxide	trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]	26042454
C052920	trimethylarsine oxide	trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	26042454\|2614406
C052920	trimethylarsine oxide	trimethylarsine oxide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 protein]	26144063
C052920	trimethylarsine oxide	trimethylarsine oxide results in increased expression of and results in increased activity of CYP1B1 protein	26042454
C052920	trimethylarsine oxide	trimethylarsine oxide results in increased expression of CYP1B1 mRNA	26042454\|2614406
C005445	triphenyl phosphate	triphenyl phosphate results in increased expression of CYP1B1 mRNA	23306105
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of CYP1B1 mRNA"	23306105
C057693	troglitazone	troglitazone results in increased expression of CYP1B1 mRNA	19140230
C057693	troglitazone	troglitazone results in increased expression of CYP1B1 mRNA	28973697
C002802	tungsten carbide	[tungsten carbide co-treated with Cobalt] results in decreased expression of CYP1B1 mRNA	18078969
C112106	UAB 30	UAB 30 results in increased expression of CYP1B1 mRNA	23292798
C022884	undecane	undecane results in increased expression of CYP1B1 protein	17337753
D014520	Urethane	Urethane results in increased expression of CYP1B1 mRNA	28818685
D014635	Valproic Acid	Valproic Acid affects the expression of CYP1B1 mRNA	25064622
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid results in decreased expression of CYP1B1 mRNA	23179753\|2519280
D014635	Valproic Acid	Valproic Acid results in increased expression of CYP1B1 mRNA	23179753\|2438349
D014635	Valproic Acid	Valproic Acid results in decreased expression of CYP1B1 mRNA	17292431
D014635	Valproic Acid	Valproic Acid results in increased expression of CYP1B1 mRNA	17292431\|2489608
D014638	Vanadates	Vanadates results in increased expression of CYP1B1 mRNA	22714537
D014639	Vanadium	Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]	23423713
D014639	Vanadium	Vanadium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23423713
D014639	Vanadium	Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of CYP1B1 protein]	23423713
D014639	Vanadium	Vanadium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]	23423713
D014640	Vancomycin	Vancomycin results in decreased expression of CYP1B1 mRNA	18930951
D001335	Vehicle Emissions	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 mRNA]	28655636
D001335	Vehicle Emissions	[Benzo(a)pyrene co-treated with Vehicle Emissions] results in decreased expression of CYP1B1 protein	20435083
D001335	Vehicle Emissions	Vehicle Emissions analog results in increased expression of CYP1B1 mRNA	12396873
D001335	Vehicle Emissions	Vehicle Emissions analog results in increased expression of CYP1B1 protein	12396873
D001335	Vehicle Emissions	"[Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of CYP1B1 mRNA"	17612574
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of CYP1B1 mRNA	15046786\|1868439
D001335	Vehicle Emissions	[Vehicle Emissions analog co-treated with Coal Tar analog co-treated with Tobacco Smoke Pollution analog] results in increased expression of CYP1B1 mRNA	22935520\|2327456
D001335	Vehicle Emissions	[Vehicle Emissions analog co-treated with Coal Tar analog] results in increased expression of CYP1B1 mRNA	22935520\|2327456
D001335	Vehicle Emissions	Vehicle Emissions analog results in decreased expression of CYP1B1 mRNA	23274566
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of CYP1B1 mRNA	24365139
D001335	Vehicle Emissions	Vehicle Emissions results in increased methylation of CYP1B1 gene	25560391
D001335	Vehicle Emissions	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]	21867498
D001335	Vehicle Emissions	Cycloheximide inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]	21867498
D001335	Vehicle Emissions	Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]	21867498
D001335	Vehicle Emissions	Vehicle Emissions analog results in increased expression of CYP1B1 mRNA	15541757
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of CYP1B1 mRNA	11751436\|1946508
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of CYP1B1 protein	21867498\|2709107
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of CYP1B1 mRNA	21295820
D014700	Verapamil	Verapamil results in decreased activity of CYP1B1 protein	18420780
C025643	vinclozolin	vinclozolin results in increased expression of CYP1B1 mRNA	22570695
C025643	vinclozolin	vinclozolin results in increased expression of CYP1B1 protein	25929820
D014800	Vitallium	Vitallium analog results in increased expression of CYP1B1 mRNA	23825117
D014801	Vitamin A	CYP1B1 protein results in increased oxidation of Vitamin A	15258110
D014801	Vitamin A	CYP1B1 protein results in increased oxidation of Vitamin A	15258110
D010205	Pantothenic Acid	Pantothenic Acid results in increased expression of CYP1B1 mRNA	19397697
D024483	Vitamin K 3	Vitamin K 3 results in increased expression of CYP1B1 mRNA	12414654
C111237	vorinostat	"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CYP1B1 mRNA"	27188386
C111237	vorinostat	vorinostat inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	15713371
C111237	vorinostat	vorinostat results in decreased expression of CYP1B1 mRNA	18769122
C111237	vorinostat	vorinostat results in increased expression of CYP1B1 mRNA	26272509
C574123	walrycin A	walrycin A results in increased expression of CYP1B1 mRNA	22314385
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased expression of CYP1B1 mRNA"	22055752
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased expression of CYP1B1 mRNA"	25208076
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased expression of CYP1B1 mRNA"	21295820
C009687	wortmannin	wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP1B1 mRNA]	26466350
C009689	xanthone	xanthone results in increased expression of CYP1B1 mRNA	23684558
D015215	Zidovudine	[Zidovudine co-treated with IFNA1 protein] results in decreased expression of CYP1B1 mRNA	20370541
C088658	zoledronic acid	zoledronic acid results in increased expression of CYP1B1 mRNA	24714768\|2559613
C519312	Zyflamend	Zyflamend inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]	22374940
C519312	Zyflamend	Zyflamend inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 protein]	22374940

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004497	monooxygenase activity	-	IDA	15258110 23821647
GO:0004497	monooxygenase activity	-	TAS	9097971
GO:0005506	iron ion binding	-	IEA	-
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	-	IDA	10871058
GO:0019825	oxygen binding	-	TAS	9097971
GO:0020037	heme binding	-	IDA	21147782
GO:0020037	heme binding	-	TAS	9097971
GO:0070330	aromatase activity	-	IEA	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001525	angiogenesis	-	IEA	-
GO:0002930	trabecular meshwork development	-	ISS	-
GO:0006725	cellular aromatic compound metabolic process	-	IEA	-
GO:0006805	xenobiotic metabolic process	-	IDA	22888116
GO:0006809	nitric oxide biosynthetic process	-	ISS	-
GO:0007155	cell adhesion	-	ISS	-
GO:0007601	visual perception	-	TAS	9097971
GO:0008202	steroid metabolic process	-	IDA	22888116
GO:0008210	estrogen metabolic process	-	IDA	23821647
GO:0008285	negative regulation of cell proliferation	-	ISS	-
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	-	ISS	-
GO:0009404	toxin metabolic process	-	IEA	-
GO:0010575	positive regulation of vascular endothelial growth factor production	-	ISS	-
GO:0016125	sterol metabolic process	-	TAS	-
GO:0019369	arachidonic acid metabolic process	-	IDA	15258110
GO:0019373	epoxygenase P450 pathway	-	TAS	-
GO:0030199	collagen fibril organization	-	ISS	-
GO:0030336	negative regulation of cell migration	-	ISS	-
GO:0032088	negative regulation of NF-kappaB transcription factor activity	-	ISS	-
GO:0033629	negative regulation of cell adhesion mediated by integrin	-	ISS	-
GO:0042572	retinol metabolic process	-	IDA	15258110
GO:0042574	retinal metabolic process	-	IDA	15258110
GO:0043065	positive regulation of apoptotic process	-	ISS	-
GO:0043542	endothelial cell migration	-	ISS	-
GO:0045766	positive regulation of angiogenesis	-	ISS	-
GO:0046427	positive regulation of JAK-STAT cascade	-	ISS	-
GO:0046466	membrane lipid catabolic process	-	ISS	-
GO:0048514	blood vessel morphogenesis	-	ISS	-
GO:0055114	oxidation-reduction process	-	TAS	9097971
GO:0061304	retinal blood vessel morphogenesis	-	ISS	-
GO:0070301	cellular response to hydrogen peroxide	-	ISS	-
GO:0071407	cellular response to organic cyclic compound	-	IDA	23275542
GO:0071603	endothelial cell-cell adhesion	-	IEA	-
GO:0097267	omega-hydroxylase P450 pathway	-	TAS	-
GO:2000377	regulation of reactive oxygen species metabolic process	-	ISS	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005739	mitochondrion	-	ISS	-
GO:0005789	endoplasmic reticulum membrane	-	TAS	-
GO:0031090	organelle membrane	-	IEA	-

KEGG ID	KEGG Term
hsa00140	Steroid hormone biosynthesis
hsa00380	Tryptophan metabolism
hsa00980	Metabolism of xenobiotics by cytochrome P450

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-1643685	Disease	TAS
R-HSA-211859	Biological oxidations	TAS
R-HSA-211897	Cytochrome P450 - arranged by substrate type	TAS
R-HSA-211945	Phase I - Functionalization of compounds	TAS
R-HSA-211976	Endogenous sterols	TAS
R-HSA-2142670	Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	TAS
R-HSA-2142753	Arachidonic acid metabolism	TAS
R-HSA-2142816	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	TAS
R-HSA-556833	Metabolism of lipids	TAS
R-HSA-5579000	Defective CYP1B1 causes Glaucoma	TAS
R-HSA-5579029	Metabolic disorders of biological oxidation enzymes	TAS
R-HSA-5668914	Diseases of metabolism	TAS
R-HSA-8978868	Fatty acid metabolism	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
14520706	Interactions between genetic polymorphism of cytochrome P450-1B1, sulfotransferase 1A1, catechol-o-methyltransferase and tobacco exposure in breast cancer risk. (2003 Nov 20)	Saintot M	Int J Cancer
28511368	Evaluation of CYP1B1 Expression, Oxidative Stress and Phase 2 Detoxification Enzyme Status in Oral Squamous Cell Carcinoma Patients. (2017 Mar)	Verma S	J Clin Diagn Res
18154112	[Properties of mammary fat in breast cancer patients: topographic, systemic and environmental factors]. (2007)	Bershtein LM	Vopr Onkol
25619313	Association between CYP1B1 gene polymorphisms and risk factors and susceptibility to laryngeal cancer. (2015 Jan 19)	Yu PJ	Med Sci Monit
15093676	Increased expression of cytochrome P4501B1 in peripheral leukocytes from lung cancer patients. (2004 Apr 21)	Wu MF	Toxicol Lett
14656940	Cytochrome P450 1B1 and catechol-O-methyltransferase polymorphisms and endometrial cancer susceptibility. (2004 Apr)	McGrath M	Carcinogenesis
12520072	Correlation between gene expression of aryl hydrocarbon receptor (AhR), hydrocarbon receptor nuclear translocator (Arnt), cytochromes P4501A1 (CYP1A1) and 1B1 (CYP1B1), and inducibility of CYP1A1 and CYP1B1 in human lymphocytes. (2003 Jan)	Lin P	Toxicol Sci
16484233	Inhibition of benzo[a]pyrene-activating enzymes and DNA binding in human bronchial epithelial BEAS-2B cells by methoxylated flavonoids. (2006 Aug)	Tsuji PA	Carcinogenesis
14504191	Detection of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer. (2003 Sep)	Zhu J	Cancer Epidemiol Biomarkers Prev
26082767	Polycyclic aromatic hydrocarbons and cytochrome P450 in HIV pathogenesis. (2015)	Rao PS	Front Microbiol
17603900	Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. (2007 Jun 30)	Fan C	BMC Cancer
12872524	Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. (2003 Jun)	Thier R	Int J Hyg Environ Health
17683074	Polymorphisms in drug metabolism genes, smoking, and p53 mutations in breast cancer. (2008 Feb)	Van Emburgh BO	Mol Carcinog
12398325	Cytochrome P450 1B1 mRNA levels in peripheral blood cells and exposure to polycyclic aromatic hydrocarbons in Chinese coke oven workers. (2002 Sep 16)	Hanaoka T	Sci Total Environ
17548691	Associations between smoking, polymorphisms in polycyclic aromatic hydrocarbon (PAH) metabolism and conjugation genes and PAH-DNA adducts in prostate tumors differ by race. (2007 Jun)	Nock NL	Cancer Epidemiol Biomarkers Prev
17496311	Genetic susceptibility according to three metabolic pathways in cancers of the lung and bladder and in myeloid leukemias in nonsmokers. (2007 Jul)	Vineis P	Ann Oncol
12183407	Genetic and environmental determinants on tissue response to in vitro carcinogen exposure and risk of breast cancer. (2002 Aug 15)	Li D	Cancer Res
27894333	Head-and-neck squamous cell carcinoma risk in smokers: no association detected between phenotype and AHR, CYP1A1, CYP1A2, or CYP1B1 genotype. (2016 Nov 28)	Jorge-Nebert LF	Hum Genomics
16530937	Cytochrome P450 1B1, a novel chemopreventive target for benzo[a]pyrene-initiated human esophageal cancer. (2007 Feb 8)	Wen X	Cancer Lett
22655262	Exposure to Polycyclic Aromatic Hydrocarbons Among Never Smokers in Golestan Province, Iran, an Area of High Incidence of Esophageal Cancer - a Cross-Sectional Study with Repeated Measurement of Urinary 1-OHPG in Two Seasons. (2012)	Islami F	Front Oncol
19182260	Effects of dioxin on vascular endothelial growth factor (VEGF) production in the retina associated with choroidal neovascularization. (2009 Jul)	Takeuchi A	Invest Ophthalmol Vis Sci
23209192	Cotinine in human placenta predicts induction of gene expression in fetal tissues. (2013 Feb)	Vyhlidal CA	Drug Metab Dispos
15471096	Occupational exposure to polycyclic aromatic hydrocarbons suppresses constitutive expression of CYP1B1 on the transcript level in human leukocytes. (2004 Sep)	Lemm F	Int J Hyg Environ Health
16557573	Sex differences in risk of lung cancer: Expression of genes in the PAH bioactivation pathway in relation to smoking and bulky DNA adducts. (2006 Aug 15)	Mollerup S	Int J Cancer
12214673	Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. (2002 Aug)	Kamataki T	Drug Metab Rev
17173682	Etiological study of esophageal squamous cell carcinoma in an endemic region: a population-based case control study in Huaian, China. (2006 Dec 15)	Wang Z	BMC Cancer
22232929	[Polymorphic markers of the CYP1B1 (4326C > G), CYP2F1 (c.14_15insC), CYP2J2 (-76G > T), and CYP2S1 (13106C > T and 13255A > G) genes and genetic predisposition to chronic respiratory diseases induced by smoking and occupational factors]. (2011 Oct)	Akhmadishina LA	Genetika
17200336	Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas. (2007 Jan 1)	Chang JT	Clin Cancer Res
17637178	Novel methoxylated flavone inhibitors of cytochrome P450 1B1 in SCC-9 human oral cancer cells. (2007 Jun)	Walle T	J Pharm Pharmacol
27203850	Effects of Cigarette Smoke Condensate on Oxidative Stress, Apoptotic Cell Death, and HIV Replication in Human Monocytic Cells. (2016)	Rao P	PLoS One
15654505	Association of habitual smoking and drinking with single nucleotide polymorphism (SNP) in 40 candidate genes: data from random population-based Japanese samples. (2005)	Liu Y	J Hum Genet
25218365	Diversified expression of aryl hydrocarbon receptor dependent genes in human laryngeal squamous cell carcinoma cell lines treated with beta-naphthoflavone. (2014 Nov 18)	Brauze D	Toxicol Lett
20179299	Effects of cigarette smoke on the human oral mucosal transcriptome. (2010 Mar)	Boyle JO	Cancer Prev Res (Phila)
12415427	Cytochrome P450 CYP1B1 and catechol O-methyltransferase (COMT) genetic polymorphisms and breast cancer susceptibility in a Turkish population. (2002 Nov)	Kocabas NA	Arch Toxicol
19860743	Effect of gene-environment Interactions on mental development in African American, Dominican, and Caucasian mothers and newborns. (2010 Jan)	Wang S	Ann Hum Genet
21475938	CYP1A1 and CYP1B1 polymorphisms as modifying factors in patients with pneumoconiosis and occupationally related tumours: A pilot study. (2009 Nov-Dec)	Schneider J	Mol Med Rep
20399842	The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation. (2010 Sep 15)	Alexandrov K	Toxicol Lett
11535249	Impact of metabolic genotypes on levels of biomarkers of genotoxic exposure. (2001 Oct 1)	Schoket B	Mutat Res
16922636	Cytochrome P450 interactions in human cancers: new aspects considering CYP1B1. (2005 Aug)	Roos PH	Expert Opin Drug Metab Toxicol
20937634	Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. (2010 Nov 1)	Cleary SP	Am J Epidemiol
22301281	Genetic variants in carcinogen-metabolizing enzymes, cigarette smoking and pancreatic cancer risk. (2012 Apr)	Jang JH	Carcinogenesis
15659568	Cytochrome P450 1A1 and 1B1 in human blood lymphocytes are not suitable as biomarkers of exposure to dioxin-like compounds: polymorphisms and interindividual variation in expression and inducibility. (2005 May)	van Duursen MB	Toxicol Sci
24448104	Cigarettes, genetic background, and menopausal timing: the presence of single nucleotide polymorphisms in cytochrome P450 genes is associated with increased risk of natural menopause in European-American smokers. (2014 Jul)	Butts SF	Menopause
15301869	Role of estrogen receptor in regulation of polycyclic aromatic hydrocarbon metabolic activation in lung. (2004 Sep)	Berge G	Lung Cancer
19575027	Genetic variation of genes for xenobiotic-metabolizing enzymes and risk of bronchial asthma: the importance of gene-gene and gene-environment interactions for disease susceptibility. (2009 Aug)	Polonikov AV	J Hum Genet
21193517	Seasonal variations in the levels of PAH-DNA adducts in young adults living in Mexico City. (2011 May)	Garcia-Suastegui WA	Mutagenesis
28714190	Polymorphisms of xenobiotic-metabolizing genes and colorectal cancer risk in patients with lynch syndrome: A retrospective cohort study in Taiwan. (2018 Jan)	Kamiza AB	Environ Mol Mutagen
9054634	Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. (1997 Feb)	Hakkola J	Carcinogenesis
25796598	Polymorphisms of the CYP1B1 gene and hepatocellular carcinoma risk in a Chinese population. (2015 Jun 10)	Liu F	Gene
24177223	Significant interactions between maternal PAH exposure and haplotypes in candidate genes on B[a]P-DNA adducts in a NYC cohort of non-smoking African-American and Dominican mothers and newborns. (2014 Jan)	Iyer S	Carcinogenesis
18573508	Association of functionally important polymorphisms in cytochrome P4501B1 with lung cancer. (2008 Aug 25)	Shah PP	Mutat Res
12107641	Cytochrome P450 1B1, a new keystone in gene-environment interactions related to human head and neck cancer? (2002 Jun)	Thier R	Arch Toxicol
19630952	Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. (2009)	Crandall CJ	Breast Cancer Res
19174490	Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women. (2009 Apr)	Cote ML	Carcinogenesis
9464503	Regiospecific expression of cytochrome P4501A1 and 1B1 in human uterine tissue. (1998 Jan 9)	Vadlamuri SV	Cancer Lett
23325794	Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo. (2013 Mar)	Schults MA	Mutagenesis
25517428	Smoking-Associated Site-Specific Differential Methylation in Buccal Mucosa in the COPDGene Study. (2015 Aug)	Wan ES	Am J Respir Cell Mol Biol
23776235	Smoke carcinogens cause bone loss through the aryl hydrocarbon receptor and induction of Cyp1 enzymes. (2013 Jul 2)	Iqbal J	Proc Natl Acad Sci U S A
27138278	Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes. (2016)	Rasmussen MK	PLoS One
23614742	Role of the aryl hydrocarbon receptor in tobacco smoke extract-induced matrix metalloproteinase-1 expression. (2013 May)	Ono Y	Exp Dermatol
17980933	CYP1B1, CYP1A1, MPO, and GSTP1 polymorphisms and lung cancer risk in never-smoking Korean women. (2008 Apr)	Yoon KA	Lung Cancer
21254355	Smoking, the xenobiotic pathway, and clubfoot. (2011 Jan)	Sommer A	Birth Defects Res A Clin Mol Teratol
12727795	TCDD-mediated alterations in the AhR-dependent pathway in Seveso, Italy, 20 years after the accident. (2003 Apr)	Landi MT	Carcinogenesis
15917149	Occupational exposure to polycyclic aromatic hydrocarbons in German industries: association between exogenous exposure and urinary metabolites and its modulation by enzyme polymorphisms. (2005 Jul 4)	Rihs HP	Toxicol Lett
17056606	Cigarette smoke-induced differential gene expression in blood cells from monozygotic twin pairs. (2007 Mar)	van Leeuwen DM	Carcinogenesis
11353763	CYP1B1 expression in human lung. (2001 Jun)	Spivack SD	Drug Metab Dispos
19443378	Genetic polymorphisms in CYP1A1, CYP1B1, COMT, GSTP1 and NAT2 genes and association with bladder cancer risk in a French cohort. (2009 May)	Fontana L	Anticancer Res
18067928	Genetic polymorphisms in cytochrome P4501B1 and susceptibility to head and neck cancer. (2008 Mar 1)	Singh AP	Mutat Res
27565807	Significant interactions between maternal PAH exposure and single nucleotide polymorphisms in candidate genes on B[ a ]P-DNA adducts in a cohort of non-smoking Polish mothers and newborns. (2016 Nov 1)	Iyer S	Carcinogenesis
19963139	Genetic polymorphisms in cytochrome P450 genes are associated with an increased risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population. (2010 Jan 1)	Tai J	Cancer Genet Cytogenet
25051309	Indoor air pollution and neural tube defects: effect modification by maternal genes. (2014 Sep)	Wang L	Epidemiology
15958554	Characterization of common CYP1B1 variants with different capacity for benzo[a]pyrene-7,8-dihydrodiol epoxide formation from benzo[a]pyrene. (2005 Jun 15)	Aklillu E	Cancer Res
21081473	Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. (2011 Feb)	Wang H	Carcinogenesis
18425393	Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer. (2008 May)	Van Emburgh BO	Oncol Rep
15896461	Rapid detection of single nucleotide polymorphisms related with lung cancer susceptibility of Chinese population. (2005 Jun 8)	Liang G	Cancer Lett
19338043	Genetic polymorphisms in glutathione S-transferases and cytochrome P450s, tobacco smoking, and risk of non-Hodgkin lymphoma. (2009 May)	Kilfoy BA	Am J Hematol
28386678	Identification of novel potential genetic predictors of urothelial bladder carcinoma susceptibility in Pakistani population. (2017 Oct)	Ali SHB	Fam Cancer
19414505	CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences. (2009 Jul)	Timofeeva MN	Carcinogenesis
12807751	Genetic effects on urinary 1-hydroxypyrene levels in a Korean population. (2003 Jun)	Yang M	Carcinogenesis
28858732	Decreased expression of cytochrome p450 1B1 in non-small cell lung cancer. (2017 Nov)	Slowikowski BK	Biomed Pharmacother
15342454	Cytochrome P450 1B1 gene polymorphisms and postmenopausal endometrial cancer risk. (2004 Sep)	Rylander-Rudqvist T	Cancer Epidemiol Biomarkers Prev
20395011	The CYP1B1 Leu432Val polymorphism contributes to lung cancer risk: evidence from 6501 subjects. (2010 Dec)	Chen B	Lung Cancer
24151610	Polymorphisms in the human cytochrome P450 and arylamine N-acetyltransferase: susceptibility to head and neck cancers. (2013)	Khlifi R	Biomed Res Int
9493761	Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity. (1998 Jan)	Hakkola J	Crit Rev Toxicol
16978616	Association of cytochrome P450 1B1 polymorphism with first-trimester miscarriage. (2006 Nov)	Karypidis AH	Fertil Steril
18784359	Polymorphisms in phase I and phase II metabolism genes and risk of chronic benzene poisoning in a Chinese occupational population. (2008 Dec)	Sun P	Carcinogenesis
15122594	GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population. (2004 Jul 1)	Hung RJ	Int J Cancer
23794133	CYP1B1 C4326G polymorphism and susceptibility to cervical cancer in Chinese Han women. (2013 Dec)	Li Y	Tumour Biol
17174438	Combinations of cytochrome P-450 genotypes and risk of early-onset lung cancer in Caucasians and African Americans: a population-based study. (2007 Mar)	Cote ML	Lung Cancer
21106301	Gender is a risk factor for lung cancer. (2011 Mar)	Gasperino J	Med Hypotheses
17498780	The influence of metabolic gene polymorphisms on urinary 1-hydroxypyrene concentrations in Chinese coke oven workers. (2007 Aug 1)	Chen B	Sci Total Environ
10797280	Expression of CYP1A1, CYP1B1 and CYP3A, and polycyclic aromatic hydrocarbon-DNA adduct formation in bronchoalveolar macrophages of smokers and non-smokers. (2000 Jun 1)	Piipari R	Int J Cancer
19138944	Impact of smoking cessation on global gene expression in the bronchial epithelium of chronic smokers. (2008 Jul)	Zhang L	Cancer Prev Res (Phila)
28854564	Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers. (2017 Aug 1)	Stueve TR	Hum Mol Genet
17063266	CYP1A1 and CYP1B1 genetic polymorphisms, smoking and breast cancer risk in a Finnish Caucasian population. (2007 Sep)	Sillanpaa P	Breast Cancer Res Treat
18258609	A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers. (2008 Jun)	Zienolddiny S	Carcinogenesis
16381670	Benzo[A]pyrene-induced oral carcinogenesis and chemoprevention: studies in bioengineered human tissue. (2006 Mar)	Walle T	Drug Metab Dispos
27285958	Cigarette smoking and hormones. (2016 Aug)	Marom-Haham L	Curr Opin Obstet Gynecol
25299224	Effects of SNPs (CYP1B12 G355T, CYP1B13 C4326G, and CYP2E1*5 G-1293C), smoking, and drinking on susceptibility to laryngeal cancer among Han Chinese. (2014)	Jin J	PLoS One
29285838	Vasomotor, urogenital, psychological, and somatic symptoms in association with CYP1B1 polymorphisms in Slovak women of different menopausal status. (2018 May)	Candrakova Cernanova V	Am J Hum Biol
25052559	Active cigarette smoking, variants in carcinogen metabolism genes and breast cancer risk among pre- and postmenopausal women in Ontario, Canada. (2014 Sep-Oct)	Cotterchio M	Breast J
22466345	Joint effects of smoking and gene variants involved in sex steroid metabolism on hot flashes in late reproductive-age women. (2012 Jun)	Butts SF	J Clin Endocrinol Metab
19996203	Smoking-Related Gene Expression in Laser Capture-Microdissected Human Lung. (2009 Dec 15)	Tan XL	Clin Cancer Res
19274671	Potential role of cytochrome P450-1B1 in the metabolic activation of 4-aminobiphenyl in humans. (2009 Aug)	Ketelslegers HB	Mol Carcinog
26095139	Gene expression profiling of cytochromes P450, ABC transporters and their principal transcription factors in the amygdala and prefrontal cortex of alcoholics, smokers and drug-free controls by qRT-PCR. (2015)	Toselli F	Xenobiotica
12844487	Cytochrome P450 1B1 gene polymorphisms and postmenopausal breast cancer risk. (2003 Sep)	Rylander-Rudqvist T	Carcinogenesis
15093273	Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke. (2004 Apr 1)	Georgiadis P	Toxicol Lett