Gene: ADRB3

155
BETA3AR
adrenoceptor beta 3
protein-coding
8p11.23
Ensembl:ENSG00000188778 MIM:109691 Vega:OTTHUMG00000164028 UniprotKB:P13945
NG_011936.1
PubMed
0   ANCO-SNPs
ND
7   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.453e-1 (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SDK10.609
LTK0.603
GJB30.582
ATP4A0.578
ZNF4690.576
FAM163A0.572
GALNTL60.567
ASB20.556
KCNG10.55
FFAR40.547

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LAYN-0.387
ADAMTS4-0.384
SEPT10-0.374
WIPF1-0.372
FAM107B-0.351
SLC35D2-0.348
LITAF-0.347
CDH19-0.346
VRK2-0.341
FAM114A1-0.341

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00368NorepinephrineSmall Molecule51-41-2ApprovedTarget
DB00571PropranololSmall Molecule525-66-6Approved|InvestigationalTarget
DB00668EpinephrineSmall Molecule51-43-4ApprovedTarget
DB00866AlprenololSmall Molecule13655-52-2Approved|WithdrawnTarget
DB00871TerbutalineSmall Molecule23031-25-6ApprovedTarget
DB00938SalmeterolSmall Molecule89365-50-4ApprovedTarget
DB00960PindololSmall Molecule13523-86-9Approved|InvestigationalTarget
DB00983FormoterolSmall Molecule73573-87-2Approved|InvestigationalTarget
DB01001SalbutamolSmall Molecule18559-94-9ApprovedTarget
DB01064IsoprenalineSmall Molecule7683-59-2Approved|InvestigationalTarget
DB01102ArbutamineSmall Molecule128470-16-6ApprovedTarget
DB01288FenoterolSmall Molecule13392-18-2Approved|InvestigationalTarget
DB01363EphedraSmall Molecule-Approved|Nutraceutical|WithdrawnTarget
DB01407ClenbuterolSmall Molecule37148-27-9Approved|InvestigationalTarget
DB01580OxprenololSmall Molecule6452-71-7ApprovedTarget
DB05395AmibegronSmall MoleculeInvestigationalTarget
DB06190SolabegronSmall Molecule252920-94-8InvestigationalTarget
DB06262DroxidopaSmall Molecule23651-95-8Approved|InvestigationalTarget
DB08807BopindololSmall Molecule62658-63-3ApprovedTarget
DB08808BupranololSmall Molecule14556-46-8ApprovedTarget
DB08893MirabegronSmall Molecule223673-61-8ApprovedTarget
DB00182AmphetamineSmall Molecule300-62-9Approved|Illicit|InvestigationalTarget
DB00217BethanidineSmall Molecule55-73-2ApprovedTarget
DB00321AmitriptylineSmall Molecule50-48-6ApprovedTarget
DB00334OlanzapineSmall Molecule132539-06-1Approved|InvestigationalTarget
DB00540NortriptylineSmall Molecule72-69-5ApprovedTarget
DB00726TrimipramineSmall Molecule739-71-9ApprovedTarget
DB01365MephentermineSmall Molecule100-92-5ApprovedTarget
DB06726BufuralolSmall Molecule54340-62-4Experimental|InvestigationalTarget
ID Drug Name Action PubMed
C0067181,12-benzoperylene"1,12-benzoperylene results in increased expression of ADRB3 mRNA"26377693
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in decreased expression of ADRB3 mRNA"28903501
C4491192-(4-(2-(((1,2)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)phenoxy)-2-methylpropionic acid"2-(4-(2-(((1,2)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)phenoxy)-2-methylpropionic acid binds to and results in increased activity of ADRB3 protein"11711302
C4491192-(4-(2-(((1,2)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)phenoxy)-2-methylpropionic acid"2-(4-(2-(((1,2)-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl)amino)ethyl)phenoxy)-2-methylpropionic acid binds to and results in increased activity of ADRB3 protein"11711302
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB3 protein"12606629
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [ICI D7114 binds to and results in increased activity of ADRB3 protein]"12606629
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB3 protein"10952688
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [cyanopindolol binds to ADRB3 protein]"10344530|1473041
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP]"10952688
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB3 protein"20930473
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate results in increased expression of ADRB3 mRNA"10725275
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"[3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate results in increased expression of ADRB3 mRNA] which results in increased susceptibility to disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"10725275
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate results in increased expression of ADRB3 protein"10725275
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB3 protein"10344530|8569714
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [amibegron results in increased activity of ADRB3 protein]"8569714
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [CGP 12177 results in increased activity of ADRB3 protein]"8569714
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]"17622774
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased expression of ADRB3 protein]"20654104
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Norepinephrine results in increased activity of ADRB3 protein]"17622774|8569714
C0978693-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate binds to and results in decreased activity of ADRB3 protein"17622774
D000082AcetaminophenAcetaminophen results in decreased expression of ADRB3 mRNA26690555
D000082AcetaminophenAcetaminophen affects the expression of ADRB3 mRNA17562736
D000082AcetaminophenAcetaminophen results in decreased expression of ADRB3 mRNA17585979
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of ADRB3 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ADRB3 mRNA]17585979
D000242Cyclic AMP"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP]"10952688
D000242Cyclic AMPADRB3 protein affects the abundance of Cyclic AMP14730417
D000242Cyclic AMP[Albuterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Alprenolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[broxaterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[CGP 12177 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[CGP 20712A binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Epinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Fenoterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Formoterol Fumarate binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[ICI 118551 binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Norepinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Pindolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000242Cyclic AMP[Salmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP14730417
D000242Cyclic AMP[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP10952688
D000242Cyclic AMP[Terbutaline binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000420AlbuterolAlbuterol binds to and results in increased activity of ADRB3 protein14730417
D000420Albuterol[Albuterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000420AlbuterolAlbuterol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D000526AlprenololAlprenolol binds to and results in increased activity of ADRB3 protein14730417
D000526Alprenolol[Alprenolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000526AlprenololAlprenolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C076252amibegronamibegron binds to and results in increased activity of ADRB3 protein16022967
C076252amibegronamibegron inhibits the reaction [ADRB3 protein results in increased susceptibility to Phenylephrine]16022967
C076252amibegron"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [amibegron results in increased activity of ADRB3 protein]"8569714
C076252amibegronamibegron binds to and results in increased activity of ADRB3 protein12208771|1865173
C076252amibegronamibegron results in increased activity of ADRB3 protein8569714
D000638AmiodaroneAmiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein]10217540
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ADRB3 mRNA16483693
C076559arbutaminearbutamine results in increased activity of ADRB3 protein8723169
D001104ArbutinArbutin results in decreased expression of ADRB3 mRNA17103032
C015001arsenitearsenite results in increased methylation of ADRB3 promoter23974009
C015001arsenitearsenite results in decreased expression of ADRB3 mRNA18191166
D001262AtenololAtenolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C100697AZ 002AZ 002 binds to and results in increased activity of ADRB3 protein8699633
C030935benz(a)anthracenebenz(a)anthracene affects the expression of ADRB3 mRNA26377693
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of ADRB3 mRNA26377693
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADRB3 mRNA18164116
D001564Benzo(a)pyreneAHR protein affects the reaction [Benzo(a)pyrene affects the expression of ADRB3 mRNA]22228805
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ADRB3 mRNA22228805
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ADRB3 mRNA22374506
D004958EstradiolEstradiol results in increased expression of ADRB3 mRNA15713686
D018723Bethanechol"[disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein] which results in decreased activity of Bethanechol"12404226
D017298BisoprololBisoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C006780bisphenol Abisphenol A results in decreased expression of ADRB3 mRNA28079927
C006780bisphenol Abisphenol A results in decreased expression of ADRB3 mRNA25181051
C039248BRL 26830ABRL 26830A binds to and results in increased activity of ADRB3 protein7520314
C063157BRL 35135BRL 35135 binds to and results in increased activity of ADRB3 protein11520059
C057368BRL 37344BRL 37344 binds to and results in increased activity of ADRB3 protein14730417|1682311
C057368BRL 37344[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
C057368BRL 37344BRL 37344 inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C057368BRL 37344BRL 37344 binds to and results in increased activity of ADRB3 protein20930473
C057368BRL 37344[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased abundance of Glucose20930473
C057368BRL 37344"[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Fatty Acids, Nonesterified"20930473
C057368BRL 37344[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Lactic Acid20930473
C057368BRL 37344[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Pyruvic Acid20930473
C057368BRL 37344BRL 37344 binds to and results in increased activity of ADRB3 protein18651730
C057368BRL 37344BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 mRNA]15009959
C057368BRL 37344BRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 protein]15009959
C057368BRL 37344BRL 37344 results in increased activity of ADRB3 protein17622774
C057368BRL 37344BRL 37344 binds to and results in increased activity of ADRB3 protein10344530|1762277
C057368BRL 37344[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased activity of OXT protein17632099
C057368BRL 37344[ICI 118551 binds to and results in decreased activity of ADRB2 protein] affects the reaction [[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased activity of OXT protein]17632099
C045916broxaterolbroxaterol binds to and results in increased activity of ADRB3 protein14730417|1664813
C045916broxaterol[broxaterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
C045916broxaterolbroxaterol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D002046BupranololBupranolol binds to and results in decreased activity of ADRB3 protein11577025
D002087ButyratesButyrates results in decreased expression of ADRB3 mRNA8120022
D002087ButyratesButyrates results in decreased expression of ADRB3 protein8120022
C043211carvedilolcarvedilol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C043211carvedilolADRB3 affects the susceptibility to carvedilol11159692
C043211carvedilolcarvedilol results in decreased expression of ADRB3 mRNA17440824
C033394CGP 12177CGP 12177 binds to ADRB3 protein21870877
C033394CGP 12177CGP 12177 binds to and results in increased activity of ADRB3 protein10952688|1175357
C033394CGP 12177[CGP 12177 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
C033394CGP 12177CGP 12177 inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C033394CGP 12177"N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide inhibits the reaction [CGP 12177 binds to ADRB3 protein]"21870877
C033394CGP 12177ADRB3 affects the susceptibility to CGP 1217711159692
C033394CGP 12177"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [CGP 12177 results in increased activity of ADRB3 protein]"8569714
C033394CGP 12177CGP 12177 binds to ADRB3 protein10217540
C033394CGP 12177CGP 12177 binds to and results in increased activity of ADRB3 protein7815362
C033394CGP 12177CGP 12177 results in increased activity of ADRB3 protein8569714
C033394CGP 12177CGP 12177 binds to and results in increased activity of ADRB3 protein9024225
C049763CGP 20712ACGP 20712A binds to and results in decreased activity of ADRB3 protein14730417
C049763CGP 20712A[CGP 20712A binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP14730417
C049763CGP 20712ACGP 20712A binds to and results in increased activity of ADRB3 protein1682311
C049763CGP 20712ACGP 20712A inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C049763CGP 20712AADRB3 affects the susceptibility to CGP 20712A11159692
D002737ChloropreneChloroprene results in decreased expression of ADRB3 mRNA23125180
D004390ChlorpyrifosChlorpyrifos affects the expression of ADRB3 mRNA18812211
D004390ChlorpyrifosChlorpyrifos results in decreased expression of ADRB3 mRNA17452286
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRB3 gene20938992
D002976ClenbuterolClenbuterol binds to and results in increased activity of ADRB3 protein7815362
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of ADRB3 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ADRB3 mRNA]17585979
D005576ColforsinColforsin results in decreased expression of ADRB3 mRNA10725275
D003471CuprizoneCuprizone results in decreased expression of ADRB3 mRNA27523638
C047975cyanopindolol"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [cyanopindolol binds to ADRB3 protein]"10344530|1473041
C047975cyanopindololAlbuterol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololAlprenolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololAtenolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololBisoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololBRL 37344 inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololbroxaterol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololcarvedilol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololCGP 12177 inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololCGP 20712A inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololcyanopindolol binds to ADRB3 protein10344530|1473041
C047975cyanopindololEpinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololFenoterol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololFormoterol Fumarate inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololICI 118551 inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololIsoproterenol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololMetoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololNorepinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololPindolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololPropranolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololSalmeterol Xinafoate inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C047975cyanopindololTerbutaline inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D003687DehydroepiandrosteroneDehydroepiandrosterone results in increased expression of ADRB3 mRNA12659879
D003907DexamethasoneDexamethasone results in decreased expression of ADRB3 mRNA10725275
D003907Dexamethasone[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of ADRB3 mRNA29288687
D003976DiazinonDiazinon affects the expression of ADRB3 mRNA18812211
D003976DiazinonDiazinon results in decreased expression of ADRB3 mRNA17452286
D004041Dietary FatsDietary Fats results in decreased expression of ADRB3 mRNA18042831|2013204
D004041Dietary FatsDietary Fats results in decreased expression of ADRB3 protein25637688
D004041Dietary FatsPlant Extracts inhibits the reaction [Dietary Fats results in decreased expression of ADRB3 mRNA]20132043
D004041Dietary FatsDietary Fats results in increased expression of ADRB3 mRNA18721800|2272001
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADRB3 mRNA18164116
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of ADRB3 mRNA21658437
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"[disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein] which results in decreased activity of Bethanechol"12404226
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"[disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein] which results in decreased activity of Muscarinic Agonists"12404226
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"L 748,337 inhibits the reaction [disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein]"12404226
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"[3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate results in increased expression of ADRB3 mRNA] which results in increased susceptibility to disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"10725275
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein"16399693
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein"11275008|1865173
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate results in increased expression of ADRB3 mRNA"20184727
C076126disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate"disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein"10344530|1240422
D004280Dobutamine[Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 mRNA19719783
D004280Dobutamine[Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 protein19719783
D004837EpinephrineEpinephrine binds to and results in increased activity of ADRB3 protein14730417|1682311
D004837Epinephrine[Epinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D004837EpinephrineEpinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D004837EpinephrineEpinephrine binds to and results in increased activity of ADRB3 protein7815362
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ADRB3 mRNA15212814
D005230Fatty Acids, Nonesterified"[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Fatty Acids, Nonesterified"20930473
D005280FenoterolFenoterol binds to and results in increased activity of ADRB3 protein14730417
D005280Fenoterol[Fenoterol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D005280FenoterolFenoterol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C117158FK 175FK 175 binds to and results in increased activity of ADRB3 protein18651730
D005419FlavonoidsFlavonoids results in increased expression of ADRB3 mRNA18035473
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRB3 gene20938992
D000068759Formoterol FumarateFormoterol Fumarate binds to and results in increased activity of ADRB3 protein14730417
D000068759Formoterol Fumarate[Formoterol Fumarate binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D000068759Formoterol FumarateFormoterol Fumarate inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C039281furanfuran results in decreased expression of ADRB3 mRNA24183702
D005947Glucose[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased abundance of Glucose20930473
D006118GriseofulvinGriseofulvin results in decreased expression of ADRB3 mRNA12735108
D017313FenretinideFenretinide results in decreased expression of ADRB3 mRNA28973697
C026777ICI 118551ICI 118551 binds to and results in decreased activity of ADRB3 protein14730417
C026777ICI 118551[ICI 118551 binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP14730417
C026777ICI 118551ICI 118551 binds to and results in increased activity of ADRB3 protein1682311
C026777ICI 118551ICI 118551 inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C026777ICI 118551[Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 mRNA19719783
C026777ICI 118551[Dobutamine co-treated with ICI 118551] results in increased expression of ADRB3 protein19719783
C026777ICI 118551[ICI 118551 binds to and results in decreased activity of ADRB2 protein] affects the reaction [[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased activity of OXT protein]17632099
C071909ICI D7114"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [ICI D7114 binds to and results in increased activity of ADRB3 protein]"12606629
C071909ICI D7114ICI D7114 binds to and results in increased activity of ADRB3 protein12606629
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ADRB3 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of ADRB3 mRNA29288687
D007545IsoproterenolIsoproterenol binds to and results in increased activity of ADRB3 protein14730417|1682311
D007545Isoproterenol[Isoproterenol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D007545IsoproterenolIsoproterenol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D007545IsoproterenolIsoproterenol results in increased activity of ADRB3 protein18553954|1882013
D007545Isoproterenol"L 748,337 inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]"18820136
D007545Isoproterenol[ADRB3 affects the expression of ADRB1 mRNA] which affects the susceptibility to Isoproterenol11159692
D007545Isoproterenol"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]"17622774
D007545Isoproterenol"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Isoproterenol results in increased expression of ADRB3 protein]"20654104
D007545IsoproterenolBRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 mRNA]15009959
D007545IsoproterenolBRL 37344 promotes the reaction [Isoproterenol results in increased expression of ADRB3 protein]15009959
D007545IsoproterenolIsoproterenol binds to and results in increased activity of ADRB3 protein7815362
D007545IsoproterenolIsoproterenol results in increased activity of ADRB3 protein17622774
D007545IsoproterenolIsoproterenol results in increased expression of ADRB3 mRNA15009959|2065410
D007545IsoproterenolIsoproterenol results in increased expression of ADRB3 protein15009959
C011890kojic acidkojic acid results in decreased expression of ADRB3 mRNA16595896
C120576L 748,337"L 748,337 inhibits the reaction [disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein]"12404226
C120576L 748,337"L 748,337 binds to and results in decreased activity of ADRB3 protein"16022967
C120576L 748,337"L 748,337 inhibits the reaction [Isoproterenol results in increased activity of ADRB3 protein]"18820136
C120576L 748,337"L 748,337 binds to and results in decreased activity of ADRB3 protein"11577025|1240422
D019344Lactic Acid[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Lactic Acid20930473
C432503licarin A[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased expression of ADRB3 mRNA29288687
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of ADRB3 mRNA"24972896
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of ADRB3 gene20938992
D008790MetoprololMetoprolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D008790MetoprololMetoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein]18703049
D008790MetoprololMetoprolol results in increased expression of ADRB3 protein18703049
D018721Muscarinic Agonists"[disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate binds to and results in increased activity of ADRB3 protein] which results in decreased activity of Muscarinic Agonists"12404226
C568515N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide"N-(3-hydroxy-1-(naphthalen-1-yl)-1,8,11-trioxa-5-azatridecan-13-yl)-6-(2-(2-(4,4-difluoro-4,4a-dihydro-5-(thiophen-2-yl)-4-bora-3a,4a-diaza-s-indacene-3-yl)vinyl)phenoxyacetamido)hexanamide inhibits the reaction [CGP 12177 binds to ADRB3 protein]"21870877
C415563N-(4-(2-((2-hydroxy-2-(3-pyridinyl)ethyl)amino)ethyl)phenyl)-4-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonamideN-(4-(2-((2-hydroxy-2-(3-pyridinyl)ethyl)amino)ethyl)phenyl)-4-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonamide binds to and results in increased activity of ADRB3 protein18651730
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ADRB3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ADRB3 mRNA"25554681|2562005
D009638NorepinephrineNorepinephrine binds to and results in increased activity of ADRB3 protein14730417|1682311
D009638Norepinephrine[Norepinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D009638NorepinephrineNorepinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D009638NorepinephrineOctopamine inhibits the reaction [Norepinephrine binds to ADRB3 protein]10344530
D009638Norepinephrine"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Norepinephrine results in increased activity of ADRB3 protein]"17622774|8569714
D009638NorepinephrineNorepinephrine binds to and results in increased activity of ADRB3 protein7815362
D009638NorepinephrineNorepinephrine results in increased activity of ADRB3 protein17622774|8569714
D009655OctopamineOctopamine results in increased activity of ADRB3 protein10344530
D009655OctopamineOctopamine inhibits the reaction [Norepinephrine binds to ADRB3 protein]10344530
D009655OctopamineOctopamine results in increased activity of ADRB3 protein10344530
D010096OxprenololOxprenolol binds to and results in increased activity of ADRB3 protein1682311
D010100OxygenOxygen deficiency results in increased expression of ADRB3 mRNA23539316
D010126OzoneOzone results in decreased expression of ADRB3 mRNA12763052|1746015
D000073878Palm OilPalm Oil results in decreased expression of ADRB3 mRNA18042831
D010634PhenobarbitalPhenobarbital results in decreased expression of ADRB3 mRNA25270620
D010656PhenylephrineADRB3 protein results in increased susceptibility to Phenylephrine16022967
D010656Phenylephrineamibegron inhibits the reaction [ADRB3 protein results in increased susceptibility to Phenylephrine]16022967
D010672PhenytoinPhenytoin results in decreased expression of ADRB3 mRNA20345932
D010869PindololPindolol binds to and results in increased activity of ADRB3 protein14730417|1682311
D010869Pindolol[Pindolol binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D010869PindololPindolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D010869PindololPindolol binds to and results in increased activity of ADRB3 protein7815362
C006253pirinixic acidpirinixic acid results in decreased expression of ADRB3 mRNA17950772
C006253pirinixic acidpirinixic acid results in increased expression of ADRB3 mRNA16306350
C006253pirinixic acidPPARA protein promotes the reaction [pirinixic acid results in decreased expression of ADRB3 mRNA]17950772
D010936Plant ExtractsPlant Extracts inhibits the reaction [Dietary Fats results in decreased expression of ADRB3 mRNA]20132043
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in decreased expression of ADRB3 mRNA28903501
D011374ProgesteroneProgesterone results in increased expression of ADRB3 mRNA15713686
D011433PropranololPropranolol inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D011433PropranololADRB3 affects the susceptibility to Propranolol11159692
D019289Pyruvic Acid[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Pyruvic Acid20930473
C089730rosiglitazonerosiglitazone results in decreased expression of ADRB3 protein17970706
C089730rosiglitazonerosiglitazone results in decreased expression of ADRB3 mRNA16306350
D000068299Salmeterol XinafoateSalmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein14730417
D000068299Salmeterol Xinafoate[Salmeterol Xinafoate binds to and results in decreased activity of ADRB3 protein] which results in decreased abundance of Cyclic AMP14730417
D000068299Salmeterol XinafoateSalmeterol Xinafoate inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
C523977solabegronsolabegron binds to and results in increased activity of ADRB3 protein18651730
D053260SootSoot results in decreased expression of ADRB3 mRNA26551751
C114929SR 59104ASR 59104A binds to and results in increased activity of ADRB3 protein10952688
C114930SR 59119A"3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP]"10952688
C114930SR 59119ASR 59119A binds to and results in increased activity of ADRB3 protein10952688
C114930SR 59119A[SR 59119A binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP10952688
D013311StreptozocinMetoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein]18703049
D013311StreptozocinStreptozocin results in increased expression of ADRB3 protein18703049
D014284TriiodothyronineAmiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein]10217540
D014284TriiodothyronineTriiodothyronine results in decreased expression of ADRB3 mRNA10217540
D014284TriiodothyronineTriiodothyronine results in decreased expression of ADRB3 protein10217540
D014284TriiodothyronineTriiodothyronine results in increased expression of ADRB3 protein8836703
D013629TamoxifenTamoxifen results in increased expression of ADRB3 mRNA25123088
D013726TerbutalineTerbutaline binds to and results in increased activity of ADRB3 protein14730417|1664813
D013726Terbutaline[Terbutaline binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP14730417
D013726TerbutalineTerbutaline inhibits the reaction [cyanopindolol binds to ADRB3 protein]14730417
D013726TerbutalineTerbutaline binds to and results in increased activity of ADRB3 protein7815362
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ADRB3 mRNA26377647
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ADRB3 mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of ADRB3 mRNA20133372
C057693troglitazone[troglitazone co-treated with TNF protein] results in decreased expression of ADRB3 mRNA12732648
D015034Zinc OxideZinc Oxide analog results in decreased expression of ADRB3 mRNA27185063

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004935adrenergic receptor activity-IBA21873635  
GO:0004939beta-adrenergic receptor activity-IDA15123695  
GO:0005515protein binding-IPI15123695  
GO:0015052beta3-adrenergic receptor activity-IBA21873635  
GO:0015052beta3-adrenergic receptor activity-IMP9892244  
GO:0031699beta-3 adrenergic receptor binding-IEA-  
GO:0042803protein homodimerization activity-IDA15123695  
GO:0051379epinephrine binding-IBA21873635  
GO:0051380norepinephrine binding-IBA21873635  
GO:0051380norepinephrine bindingcontributes_toIDA15123695  
GO ID GO Term Qualifier Evidence PubMed
GO:0001659temperature homeostasis-IBA21873635  
GO:0002024diet induced thermogenesis-IEA-  
GO:0002025norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure-IBA21873635  
GO:0002032desensitization of G-protein coupled receptor protein signaling pathway by arrestinNOTIDA15123695  
GO:0005975carbohydrate metabolic process-TAS2570461  
GO:0006091generation of precursor metabolites and energy-TAS2570461  
GO:0006112energy reserve metabolic process-TAS1718744  
GO:0006898receptor-mediated endocytosisNOTIDA15123695  
GO:0007186G-protein coupled receptor signaling pathway-TAS-  
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-TAS2570461  
GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathway-IBA21873635  
GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathway-TAS1718744  
GO:0007190activation of adenylate cyclase activity-IDA15123695  
GO:0007267cell-cell signaling-IBA21873635  
GO:0007568aging-IEA-  
GO:0009409response to cold-IEA-  
GO:0031649heat generation-IEA-  
GO:0040015negative regulation of multicellular organism growth-IEA-  
GO:0042755eating behavior-IEA-  
GO:0043410positive regulation of MAPK cascade-IDA15123695  
GO:0046677response to antibiotic-IEA-  
GO:0050873brown fat cell differentiation-IEA-  
GO:0071880adenylate cyclase-activating adrenergic receptor signaling pathway-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IBA21873635  
GO:0005887integral component of plasma membrane-TAS1718744  
GO:0043235receptor complex-IDA15123695  
KEGG ID KEGG Term
hsa04020Calcium signaling pathway
hsa04080Neuroactive ligand-receptor interaction
hsa04144Endocytosis
hsa04970Salivary secretion
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-373076Class A/1 (Rhodopsin-like receptors)TAS
R-HSA-375280Amine ligand-binding receptorsTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-390696AdrenoceptorsTAS
R-HSA-418555G alpha (s) signalling eventsTAS
R-HSA-500792GPCR ligand bindingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
14671190The Trp(64)Arg polymorphism of the beta(3)-adrenergic receptor gene is not associated with body weight or body mass index in Japanese: a longitudinal analysis. (2003 Dec)Matsushita YJ Clin Endocrinol Metab
22550477ADRB3 polymorphism associated with BMI gain in Japanese men. (2012)Takeuchi SExp Diabetes Res
20536507Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients. (2010 Apr)Wang YDiabet Med
19193342Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. (2008 Sep)Ujike HJ Clin Psychiatry
25516658Case-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan. (2014 Dec 14)Kuruma SWorld J Gastroenterol
17345789Relationship between metabolic syndrome and Trp64arg polymorphism of the beta-adrenergic receptor gene in a general sample: the Shigaraki study. (2006 Nov)Tamaki SHypertens Res
25102261Maternal folate, alcohol and energy metabolism-related gene polymorphisms and the risk of recurrent pregnancy loss. (2012 Oct)Sata FJ Dev Orig Health Dis