Gene info: ID 1571

Gene: CYP2E1

GENE ID: 1571

Synonyms: CPE1|CYP2E|P450-J|P450C2E

Description: cytochrome P450 family 2 subfamily E member 1

Gene type: protein-coding

Location: 10q26.3

dbXrefs: Ensembl:ENSG00000130649 MIM:124040 Vega:OTTHUMG00000019322 UniprotKB:P05181

RefSeq: NG_008383.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: CD|ND|AD

# Publications: 272

Sherlock p-value : NA (AD) 3.914e-1 (ND) (Frontal_Cortex)

Pascal p-value : 2.844e-1 (AD) 2.108e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
TRIM46	0.883
TRO	0.883
ME3	0.883
RPS6KL1	0.881
PNMA3	0.878
TRIM3	0.878
ZFR2	0.877
COG1	0.877
DRP2	0.876
SYCE1	0.875

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
MTRNR2L10	-0.508
YES1	-0.502
MTRNR2L9	-0.5
MTRNR2L6	-0.493
WWTR1	-0.493
MTRNR2L8	-0.486
RAB13	-0.477
MTRNR2L2	-0.468
CLEC2B	-0.462
PHEX	-0.46

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB11994	Diacerein	Small Molecule	13739-02-1	Approved\|Investigational	Target
DB00041	Aldesleukin	BiotechDrug	110942-02-4	Approved	Enzyme
DB00109	Enfuvirtide	BiotechDrug	159519-65-0	Approved\|Investigational	Enzyme
DB00118	Ademetionine	Small Molecule	29908-03-0	Approved\|Investigational\|Nutraceutical	Enzyme
DB00158	Folic Acid	Small Molecule	59-30-3	Approved\|Nutraceutical	Enzyme
DB00170	Menadione	Small Molecule	58-27-5	Approved\|Nutraceutical	Enzyme
DB00176	Fluvoxamine	Small Molecule	54739-18-3	Approved\|Investigational	Enzyme
DB00184	Nicotine	Small Molecule	54-11-5	Approved	Enzyme
DB00201	Caffeine	Small Molecule	58-08-2	Approved	Enzyme
DB00203	Sildenafil	Small Molecule	139755-83-2	Approved\|Investigational	Enzyme
DB00208	Ticlopidine	Small Molecule	55142-85-3	Approved	Enzyme
DB00215	Citalopram	Small Molecule	59729-33-8	Approved	Enzyme
DB00228	Enflurane	Small Molecule	13838-16-9	Approved\|Investigational	Enzyme
DB00250	Dapsone	Small Molecule	80-08-0	Approved\|Investigational	Enzyme
DB00255	Diethylstilbestrol	Small Molecule	56-53-1	Approved\|Investigational	Enzyme
DB00257	Clotrimazole	Small Molecule	23593-75-1	Approved	Enzyme
DB00259	Sulfanilamide	Small Molecule	63-74-1	Approved	Enzyme
DB00277	Theophylline	Small Molecule	58-55-9	Approved	Enzyme
DB00316	Acetaminophen	Small Molecule	103-90-2	Approved	Enzyme
DB00321	Amitriptyline	Small Molecule	50-48-6	Approved	Enzyme
DB00347	Trimethadione	Small Molecule	127-48-0	Approved	Enzyme
DB00356	Chlorzoxazone	Small Molecule	95-25-0	Approved	Enzyme
DB00359	Sulfadiazine	Small Molecule	68-35-9	Approved\|Investigational	Enzyme
DB00363	Clozapine	Small Molecule	5786-21-0	Approved	Enzyme
DB00371	Meprobamate	Small Molecule	57-53-4	Approved\|Illicit	Enzyme
DB00379	Mexiletine	Small Molecule	31828-71-4	Approved\|Investigational	Enzyme
DB00428	Streptozocin	Small Molecule	18883-66-4	Approved\|Investigational	Enzyme
DB00458	Imipramine	Small Molecule	50-49-7	Approved	Enzyme
DB00468	Quinine	Small Molecule	130-95-0	Approved	Enzyme
DB00477	Chlorpromazine	Small Molecule	50-53-3	Approved\|Investigational	Enzyme
DB00501	Cimetidine	Small Molecule	51481-61-9	Approved\|Investigational	Enzyme
DB00503	Ritonavir	Small Molecule	155213-67-5	Approved\|Investigational	Enzyme
DB00514	Dextromethorphan	Small Molecule	125-71-3	Approved	Enzyme
DB00526	Oxaliplatin	Small Molecule	61825-94-3	Approved\|Investigational	Enzyme
DB00540	Nortriptyline	Small Molecule	72-69-5	Approved	Enzyme
DB00549	Zafirlukast	Small Molecule	107753-78-6	Approved\|Investigational	Enzyme
DB00586	Diclofenac	Small Molecule	15307-86-5	Approved	Enzyme
DB00593	Ethosuximide	Small Molecule	77-67-8	Approved	Enzyme
DB00599	Thiopental	Small Molecule	76-75-5	Approved	Enzyme
DB00617	Paramethadione	Small Molecule	115-67-3	Approved	Enzyme
DB00622	Nicardipine	Small Molecule	55985-32-5	Approved\|Investigational	Enzyme
DB00623	Fluphenazine	Small Molecule	69-23-8	Approved	Enzyme
DB00633	Dexmedetomidine	Small Molecule	113775-47-6	Approved	Enzyme
DB00636	Clofibrate	Small Molecule	637-07-0	Approved\|Investigational	Enzyme
DB00655	Estrone	Small Molecule	53-16-7	Approved	Enzyme
DB00675	Tamoxifen	Small Molecule	10540-29-1	Approved	Enzyme
DB00679	Thioridazine	Small Molecule	50-52-2	Approved\|Withdrawn	Enzyme
DB00683	Midazolam	Small Molecule	59467-70-8	Approved\|Illicit	Enzyme
DB00690	Flurazepam	Small Molecule	17617-23-1	Approved\|Illicit\|Investigational	Enzyme
DB00703	Methazolamide	Small Molecule	554-57-4	Approved	Enzyme
DB00748	Carbinoxamine	Small Molecule	486-16-8	Approved	Enzyme
DB00752	Tranylcypromine	Small Molecule	155-09-9	Approved\|Investigational	Enzyme
DB00753	Isoflurane	Small Molecule	26675-46-7	Approved	Enzyme
DB00763	Methimazole	Small Molecule	60-56-0	Approved	Enzyme
DB00773	Etoposide	Small Molecule	33419-42-0	Approved	Enzyme
DB00780	Phenelzine	Small Molecule	51-71-8	Approved	Enzyme
DB00818	Propofol	Small Molecule	2078-54-8	Approved\|Investigational	Enzyme
DB00822	Disulfiram	Small Molecule	97-77-8	Approved	Enzyme
DB00829	Diazepam	Small Molecule	439-14-5	Approved\|Illicit\|Investigational	Enzyme
DB00835	Brompheniramine	Small Molecule	86-22-6	Approved	Enzyme
DB00851	Dacarbazine	Small Molecule	4342-03-4	Approved\|Investigational	Enzyme
DB00882	Clomifene	Small Molecule	911-45-5	Approved\|Investigational	Enzyme
DB00883	Isosorbide Dinitrate	Small Molecule	87-33-2	Approved\|Investigational	Enzyme
DB00898	Ethanol	Small Molecule	64-17-5	Approved	Enzyme
DB00904	Ondansetron	Small Molecule	99614-02-5	Approved	Enzyme
DB00908	Quinidine	Small Molecule	56-54-2	Approved\|Investigational	Enzyme
DB00918	Almotriptan	Small Molecule	154323-57-6	Approved\|Investigational	Enzyme
DB00949	Felbamate	Small Molecule	25451-15-4	Approved	Enzyme
DB00951	Isoniazid	Small Molecule	54-85-3	Approved\|Investigational	Enzyme
DB00969	Alosetron	Small Molecule	122852-42-0	Approved\|Withdrawn	Enzyme
DB00972	Azelastine	Small Molecule	58581-89-8	Approved	Enzyme
DB01007	Tioconazole	Small Molecule	65899-73-2	Approved	Enzyme
DB01011	Metyrapone	Small Molecule	54-36-4	Approved\|Investigational	Enzyme
DB01028	Methoxyflurane	Small Molecule	76-38-0	Approved\|Investigational	Enzyme
DB01037	Selegiline	Small Molecule	14611-51-9	Approved\|Investigational	Enzyme
DB01041	Thalidomide	Small Molecule	50-35-1	Approved\|Investigational\|Withdrawn	Enzyme
DB01045	Rifampicin	Small Molecule	13292-46-1	Approved	Enzyme
DB01068	Clonazepam	Small Molecule	1622-61-3	Approved\|Illicit	Enzyme
DB01079	Tegaserod	Small Molecule	145158-71-0	Approved\|Investigational\|Withdrawn	Enzyme
DB01085	Pilocarpine	Small Molecule	92-13-7	Approved\|Investigational	Enzyme
DB01100	Pimozide	Small Molecule	2062-78-4	Approved	Enzyme
DB01110	Miconazole	Small Molecule	22916-47-8	Approved\|Investigational	Enzyme
DB01115	Nifedipine	Small Molecule	21829-25-4	Approved	Enzyme
DB01127	Econazole	Small Molecule	27220-47-9	Approved	Enzyme
DB01131	Proguanil	Small Molecule	500-92-5	Approved	Enzyme
DB01136	Carvedilol	Small Molecule	72956-09-3	Approved\|Investigational	Enzyme
DB01151	Desipramine	Small Molecule	50-47-5	Approved\|Investigational	Enzyme
DB01156	Bupropion	Small Molecule	34911-55-2	Approved	Enzyme
DB01159	Halothane	Small Molecule	151-67-7	Approved	Enzyme
DB01167	Itraconazole	Small Molecule	84625-61-6	Approved\|Investigational	Enzyme
DB01173	Orphenadrine	Small Molecule	83-98-7	Approved	Enzyme
DB01174	Phenobarbital	Small Molecule	50-06-6	Approved\|Investigational	Enzyme
DB01191	Dexfenfluramine	Small Molecule	3239-44-9	Approved\|Illicit\|Investigational\|Withdrawn	Enzyme
DB01198	Zopiclone	Small Molecule	43200-80-2	Approved	Enzyme
DB01204	Mitoxantrone	Small Molecule	65271-80-9	Approved\|Investigational	Enzyme
DB01213	Fomepizole	Small Molecule	7554-65-6	Approved	Enzyme
DB01223	Aminophylline	Small Molecule	317-34-0	Approved	Enzyme
DB01234	Dexamethasone	Small Molecule	50-02-2	Approved\|Investigational	Enzyme
DB01236	Sevoflurane	Small Molecule	28523-86-6	Approved	Enzyme
DB01296	Glucosamine	Small Molecule	3416-24-8	Approved\|Investigational	Enzyme
DB01355	Hexobarbital	Small Molecule	56-29-1	Approved	Enzyme
DB01394	Colchicine	Small Molecule	64-86-8	Approved	Enzyme
DB01403	Methotrimeprazine	Small Molecule	60-99-1	Approved\|Investigational	Enzyme
DB01412	Theobromine	Small Molecule	83-67-0	Approved\|Investigational	Enzyme
DB01435	Antipyrine	Small Molecule	60-80-0	Approved\|Investigational	Enzyme
DB01544	Flunitrazepam	Small Molecule	1622-62-4	Approved\|Illicit	Enzyme
DB01558	Bromazepam	Small Molecule	1812-30-2	Approved\|Illicit\|Investigational	Enzyme
DB01586	Ursodeoxycholic acid	Small Molecule	128-13-2	Approved\|Investigational	Enzyme
DB01595	Nitrazepam	Small Molecule	146-22-5	Approved	Enzyme
DB01628	Etoricoxib	Small Molecule	202409-33-4	Approved\|Investigational	Enzyme
DB02701	Nicotinamide	Small Molecule	98-92-0	Approved\|Investigational	Enzyme
DB03783	Phenacetin	Small Molecule	62-44-2	Withdrawn	Enzyme
DB04794	Bifonazole	Small Molecule	60628-96-8	Approved\|Investigational	Enzyme
DB04858	Tirapazamine	Small Molecule	27314-97-2	Investigational	Enzyme
DB04920	Clevidipine	Small Molecule	167221-71-8	Approved\|Investigational	Enzyme
DB04946	Iloperidone	Small Molecule	133454-47-4	Approved	Enzyme
DB04977	Plitidepsin	Small Molecule	137219-37-5	Investigational	Enzyme
DB05109	Trabectedin	Small Molecule	114899-77-3	Approved\|Investigational	Enzyme
DB05708	GTS-21	Small Molecule	148372-04-7	Investigational	Enzyme
DB06201	Rufinamide	Small Molecule	106308-44-5	Approved	Enzyme
DB06370	Indisulam	Small Molecule	165668-41-7	Investigational	Enzyme
DB06595	Midostaurin	Small Molecule	120685-11-2	Approved\|Investigational	Enzyme
DB06637	Dalfampridine	Small Molecule	504-24-5	Approved	Enzyme
DB06689	Ethanolamine Oleate	Small Molecule	2272-11-9	Approved	Enzyme
DB06712	Nilvadipine	Small Molecule	75530-68-6	Approved\|Investigational	Enzyme
DB06728	Aniline	Small Molecule	62-53-3	Experimental	Enzyme
DB06770	Benzyl alcohol	Small Molecule	100-51-6	Approved	Enzyme
DB06774	Capsaicin	Small Molecule	404-86-4	Approved	Enzyme
DB08846	Ellagic Acid	Small Molecule	476-66-4	Investigational	Enzyme
DB08868	Fingolimod	Small Molecule	162359-55-9	Approved\|Investigational	Enzyme
DB09120	Zucapsaicin	Small Molecule	25775-90-0	Approved\|Investigational	Enzyme
DB09328	Vayarin	Small Molecule		Approved\|Investigational	Enzyme
DB09462	Glycerin	Small Molecule	56-81-5	Approved\|Investigational	Enzyme
DB11943	Delafloxacin	Small Molecule	189279-58-1	Approved\|Investigational	Enzyme
DB13174	Rhein	Small Molecule	478-43-3	Experimental	Enzyme
DB13941	Piperaquine	Small Molecule	4085-31-8	Approved\|Investigational	Enzyme

ID	Drug Name	Action	PubMed
C072959	1,1,1,2-tetrafluoro-2-chloroethane	"CYP2E1 protein results in increased metabolism of 1,1,1,2-tetrafluoro-2-chloroethane"	1686224
C495657	1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane	"CYP2E1 protein results in increased hydroxylation of 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane"	9047321
C024566	1,1,1-trichloroethane	"CYP2E1 protein results in increased oxidation of 1,1,1-trichloroethane"	1664256
C068320	1,1-dichloro-1-fluoroethane	"CYP2E1 protein affects the metabolism of 1,1-dichloro-1-fluoroethane"	11684366\|8104122
C068320	1,1-dichloro-1-fluoroethane	"CYP2E1 protein affects the susceptibility to 1,1-dichloro-1-fluoroethane"	11407538
C068320	1,1-dichloro-1-fluoroethane	"CYP2E1 protein results in increased reduction of 1,1-dichloro-1-fluoroethane"	11407538\|9173683
C501196	1,1-dichloroethane	"1,1-dichloroethane results in increased activity of CYP2E1 protein"	11606809
C501196	1,1-dichloroethane	"1,1-dichloroethane results in increased expression of and results in increased activity of CYP2E1 protein"	11606809
C501196	1,1-dichloroethane	"1,1-dichloroethane results in increased expression of CYP2E1 protein"	11606809
C561619	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea	1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea results in increased expression of CYP2E1 mRNA	21383588
C030387	1,2,3,5-tetrachlorobenzene	"CYP2E1 protein results in increased metabolism of 1,2,3,5-tetrachlorobenzene"	7747284
C030387	1,2,3,5-tetrachlorobenzene	"CYP2E1 protein results in increased oxidation of 1,2,3,5-tetrachlorobenzene"	7747284
C018673	1,2,4,5-tetrachlorobenzene	"1,2,4,5-tetrachlorobenzene results in increased expression of CYP2E1 protein"	10696772
C009947	1,2,4-trichlorobenzene	"CYP2E1 protein results in increased metabolism of 1,2,4-trichlorobenzene"	7747284
C009947	1,2,4-trichlorobenzene	"CYP2E1 protein results in increased oxidation of 1,2,4-trichlorobenzene"	7747284
C026486	1,2,5,6-dibenzanthracene	"1,2,5,6-dibenzanthracene results in increased expression of CYP2E1 mRNA"	16269432
C035384	1,2-dichloroethylene	"1,2-dichloroethylene inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]"	10828257
C035384	1,2-dichloroethylene	"1,2-dichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein]"	9851676
C035384	1,2-dichloroethylene	"1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Trichloroethylene]"	7871537
C035384	1,2-dichloroethylene	"1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride]"	7871537
C035384	1,2-dichloroethylene	"1,2-dichloroethylene results in decreased activity of CYP2E1 protein"	15205388\|2012731
C035384	1,2-dichloroethylene	"1,2-dichloroethylene results in decreased expression of CYP2E1 protein"	9671540
C035384	1,2-dichloroethylene	"1,2-dichloroethylene results in decreased activity of CYP2E1 protein"	9458004
C118009	1,2-epoxy-4-vinylcyclohexane	"[CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene] which results in increased abundance of 1,2-epoxy-4-vinylcyclohexane"	11368546
C517214	12-hydroxyellipticine	CYP2E1 protein results in increased chemical synthesis of 12-hydroxyellipticine	22917556
C031763	1,3-butadiene	"CYP2E1 protein affects the metabolism of 1,3-butadiene"	15470755
C031763	1,3-butadiene	"1,2-dichloroethylene inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]"	10828257
C031763	1,3-butadiene	"1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]"	10828257
C031763	1,3-butadiene	"CYP2E1 protein results in increased oxidation of 1,3-butadiene"	10828257
C028491	1,3-butylene glycol	"1,3-butylene glycol results in increased activity of CYP2E1 protein"	2919394
C028491	1,3-butylene glycol	"1,3-butylene glycol results in increased expression of CYP2E1 protein"	2919394
C038983	1,3-dimethylthiourea	"1,3-dimethylthiourea results in increased expression of CYP2E1 protein"	10190572
C517215	13-hydroxyellipticine	CYP2E1 protein results in increased chemical synthesis of 13-hydroxyellipticine	22917556
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	"CTNNB1 gene mutant form affects the susceptibility to [1,4-bis(2-(3,5-dichloropyridyloxy))benzene affects the expression of CYP2E1 protein]"	21705713
C025223	1,4-dioxane	"1,4-dioxane results in increased activity of CYP2E1 protein"	15490126
C025223	1,4-dioxane	"1,4-dioxane results in increased expression of and results in increased activity of CYP2E1 protein"	15490126
C025223	1,4-dioxane	"1,4-dioxane results in increased expression of CYP2E1 mRNA"	15490126
C035342	1,4-naphthoquinone	"CYP2E1 protein results in increased abundance of 1,4-naphthoquinone"	16243959
C055986	19-hydroxy-5,8,11,14-eicosatetraenoic acid	"CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid"	15205388
C033020	1-aminobenzotriazole	1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]	25243916
C033020	1-aminobenzotriazole	1-aminobenzotriazole results in decreased activity of CYP2E1 protein	15618748
C033020	1-aminobenzotriazole	1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane]	12704224
C033020	1-aminobenzotriazole	"1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]"	10828257
C033020	1-aminobenzotriazole	1-aminobenzotriazole results in decreased activity of CYP2E1 protein	27421776
C118559	1-bromopropane	CYP2E1 protein results in increased susceptibility to 1-bromopropane	19638432
C065833	1-hydroxymethylpyrene	Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene]	25243916
C065833	1-hydroxymethylpyrene	[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene	25243916
C065833	1-hydroxymethylpyrene	[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene	25243916
C053035	1-methylpyrene	1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]	25243916
C053035	1-methylpyrene	Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]	25243916
C053035	1-methylpyrene	[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene	25243916\|2791384
C053035	1-methylpyrene	[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene	25243916
C029350	1-naphthol	CYP2E1 protein results in increased abundance of 1-naphthol	16243959
C024336	1-phenylazo-2-naphthol	CYP2E1 protein results in increased oxidation of 1-phenylazo-2-naphthol	17159775
C037738	1-phenylimidazole	1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]	21842885
C037738	1-phenylimidazole	1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C037738	1-phenylimidazole	1-phenylimidazole results in decreased activity of CYP2E1 protein	7710944
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of CYP2E1 mRNA"	26808241
C067411	2,2-dichloro-1,1,1-trifluoroethane	"2,2-dichloro-1,1,1-trifluoroethane results in increased activity of CYP2E1 protein"	12919722
C067411	2,2-dichloro-1,1,1-trifluoroethane	"CYP2E1 protein results in increased susceptibility to 2,2-dichloro-1,1,1-trifluoroethane"	12451447
C067411	2,2-dichloro-1,1,1-trifluoroethane	"CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane"	11684365
C067411	2,2-dichloro-1,1,1-trifluoroethane	"2,2-dichloro-1,1,1-trifluoroethane results in decreased activity of CYP2E1 protein"	12378954
C067411	2,2-dichloro-1,1,1-trifluoroethane	"2,2-dichloro-1,1,1-trifluoroethane results in decreased activity of CYP2E1 protein"	9144458
C067411	2,2-dichloro-1,1,1-trifluoroethane	"allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane]"	7956723
C067411	2,2-dichloro-1,1,1-trifluoroethane	"CYP2E1 protein affects the metabolism of 2,2-dichloro-1,1,1-trifluoroethane"	11322177\|1168436
C067411	2,2-dichloro-1,1,1-trifluoroethane	"CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane"	7956723
C067411	2,2-dichloro-1,1,1-trifluoroethane	"CYP2E1 protein results in increased reduction of 2,2-dichloro-1,1,1-trifluoroethane"	9144458
C111118	2',3,3',4',5-pentachloro-4-hydroxybiphenyl	"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CYP2E1 mRNA"	19114083
C039673	2,3,5,6-tetrachlorophenate	"CYP2E1 protein results in increased oxidation of 2,3,5,6-tetrachlorophenate"	7747284
C056693	2,3,5-trichlorophenol	"CYP2E1 protein results in increased oxidation of 2,3,5-trichlorophenol"	7747284
C014211	2,3,7,8-tetrachlorodibenzofuran	"2,3,7,8-tetrachlorodibenzofuran results in increased expression of CYP2E1 mRNA"	25768209
C076159	2,3-dichloro-1-propanol	"CYP2E1 protein affects the susceptibility to 2,3-dichloro-1-propanol"	9129171
C541132	2,4,4',5-tetrachlorobiphenyl	"[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,4,4',5-tetrachlorobiphenyl"	27913846
C541132	2,4,4',5-tetrachlorobiphenyl	"[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,4,4',5-tetrachlorobiphenyl] which results in increased mutagenesis of HPRT1 gene"	27913846
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of CYP2E1 mRNA	11306697
C009407	2,5,2',5'-tetrachlorobiphenyl	"[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,5,2',5'-tetrachlorobiphenyl"	27913846
C009407	2,5,2',5'-tetrachlorobiphenyl	"[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 2,5,2',5'-tetrachlorobiphenyl] which results in increased mutagenesis of HPRT1 gene"	27913846
C028519	2,6-dimethylnaphthalene	"CYP2E1 protein results in increased oxidation of 2,6-dimethylnaphthalene"	17156750
C007766	2,6-xylidine	"CYP2E1 protein affects the metabolism of 2,6-xylidine metabolite"	11409937
C007766	2,6-xylidine	"fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of 2,6-xylidine metabolite]"	11409937
C104935	2-(allylthio)pyrazine	2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	9065729
C104935	2-(allylthio)pyrazine	2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]	9065729
C104935	2-(allylthio)pyrazine	2-(allylthio)pyrazine results in decreased activity of CYP2E1 protein	9065729
C104935	2-(allylthio)pyrazine	2-(allylthio)pyrazine results in decreased expression of CYP2E1 mRNA	9065729
C104935	2-(allylthio)pyrazine	2-(allylthio)pyrazine results in decreased expression of CYP2E1 protein	9065729
C581356	2-amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine	"2-amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine inhibits the reaction [Dexamethasone results in increased expression of CYP2E1 mRNA]"	20501703
C003898	2-anisidine	CYP2E1 protein results in increased oxidation of 2-anisidine	15828049
C003898	2-anisidine	CYP2E1 protein results in increased oxidation of 2-anisidine	16601807
C034047	2-cresol	CYP2E1 protein affects the metabolism of 2-cresol	8592870
C004726	2-dichlorobenzene	CYP2E1 protein results in increased metabolism of 2-dichlorobenzene	7747284
C004726	2-dichlorobenzene	CYP2E1 protein results in increased oxidation of 2-dichlorobenzene	7747284\|9817075
C004726	2-dichlorobenzene	[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene	9817075
C004726	2-dichlorobenzene	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]	9817075
C004726	2-dichlorobenzene	[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein	24713513
C004726	2-dichlorobenzene	[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene	9817075
C004726	2-dichlorobenzene	CYP2E1 protein results in increased oxidation of 2-dichlorobenzene	9817075
C004726	2-dichlorobenzene	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]	9817075
C586542	2'-(glutathion-S-yl)-deschlorodiclofenac	[CYP2E1 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac	24246759
C511621	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA]	28673560
C028405	2-naphthol	CYP2E1 protein results in increased abundance of 2-naphthol	16243959
C005328	2-nitroanisole	CYP2E1 protein results in increased metabolism of 2-nitroanisole	15144223
C005328	2-nitroanisole	CYP2E1 protein results in increased oxidation of 2-nitroanisole	17159769\|2121810
C005328	2-nitroanisole	CYP2E1 protein results in increased oxidation of 2-nitroanisole	21218109
C045573	2-nitrophenol	CYP2E1 protein affects the chemical synthesis of 2-nitrophenol	11409192
C045573	2-nitrophenol	CYP2E1 protein results in increased oxidation of 2-nitrophenol	17159769
C045573	2-nitrophenol	CYP2E1 protein affects the chemical synthesis of 2-nitrophenol	11409192
C045573	2-nitrophenol	CYP2E1 protein affects the chemical synthesis of 2-nitrophenol	11409192
C045573	2-nitrophenol	CYP2E1 protein results in increased oxidation of 2-nitrophenol	20027144
C043384	2-piperidone	CYP2E1 protein results in increased abundance of 2-piperidone	23811823
C026114	2-xylene	CYP2E1 protein results in increased metabolism of 2-xylene	8558417
C026114	2-xylene	CYP2E1 protein results in increased oxidation of 2-xylene	17156750
C026114	2-xylene	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene]	8558417
C026114	2-xylene	2-xylene results in increased expression of CYP2E1 protein	8517779\|8996725
C026114	2-xylene	Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein]	8996725
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2E1 mRNA"	28673560
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP2E1 mRNA"	19692669\|2319667
C024370	3,4-epoxy-1-butene	"3,4-epoxy-1-butene results in decreased activity of CYP2E1 protein"	24561005
C571631	3-bromomethcathinone	CYP2E1 protein results in increased metabolism of 3-bromomethcathinone	27320963
C482258	3'-hydroxy-genistein	CYP2E1 protein results in increased chemical synthesis of 3'-hydroxy-genistein	12814970
C093383	3-methylbenzaldehyde	3-methylbenzaldehyde results in decreased activity of CYP2E1 protein	12791539
C031285	3-xylene	CYP2E1 protein results in increased hydrolysis of 3-xylene	10353308
C031285	3-xylene	CYP2E1 protein results in increased metabolism of 3-xylene	8558417
C031285	3-xylene	CYP2E1 protein results in increased oxidation of 3-xylene	17156750
C031285	3-xylene	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene]	8558417
C031285	3-xylene	3-xylene affects the activity of CYP2E1 protein	15204773\|8598570
C031285	3-xylene	3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]	8889796
C031285	3-xylene	3-xylene results in decreased activity of CYP2E1 protein	12791539
C031285	3-xylene	3-xylene results in increased activity of CYP2E1 protein	8889796
C031285	3-xylene	3-xylene results in increased expression of CYP2E1 protein	8517779
C031285	3-xylene	CYP2E1 protein results in increased oxidation of 3-xylene	18247580
C008745	4,4'-bisphenol F	"CYP2E1 protein results in increased glutathionylation of 4,4'-bisphenol F metabolite"	23470418
C008745	4,4'-bisphenol F	"CYP2E1 protein results in increased hydroxylation of 4,4'-bisphenol F"	23470418
C570106	4,4'-cyclohexylidenebisphenol	"CYP2E1 protein results in increased glutathionylation of 4,4'-cyclohexylidenebisphenol"	23470418
C570106	4,4'-cyclohexylidenebisphenol	"CYP2E1 protein results in increased hydroxylation of 4,4'-cyclohexylidenebisphenol"	23470418
C106616	4,4'-dimethylbiphenyl	"CYP2E1 protein results in increased oxidation of 4,4'-dimethylbiphenyl"	17156750
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	28385499
C090942	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	28385499
C583074	4,4'-hexafluorisopropylidene diphenol	"CYP2E1 protein results in increased hydroxylation of 4,4'-hexafluorisopropylidene diphenol"	23470418
C545880	4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide	"CYP2E1 protein results in increased metabolism of 4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide"	19697924
C027226	(4-amidinophenyl)methanesulfonyl fluoride	(4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C006757	4-biphenylamine	CYP2E1 gene mutant form results in decreased susceptibility to 4-biphenylamine	25601990
C006757	4-biphenylamine	CYP2E1 protein results in increased hydroxylation of 4-biphenylamine	25601990
C006757	4-biphenylamine	[CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species	25601990
C519197	4-bromostyrene	CYP2E1 results in increased metabolism of and results in increased susceptibility to 4-bromostyrene	22366341
C422704	4-chlorostyrene	CYP2E1 results in increased metabolism of and results in increased susceptibility to 4-chlorostyrene	22366341
C032538	4-cresol	CYP2E1 protein affects the metabolism of 4-cresol	8592870
C032538	4-cresol	CYP2E1 protein results in increased metabolism of 4-cresol	16174805
C018511	4-dichlorobenzene	CYP2E1 protein results in increased metabolism of 4-dichlorobenzene	7747284
C018511	4-dichlorobenzene	CYP2E1 protein results in increased oxidation of 4-dichlorobenzene	7747284\|9817075
C018511	4-dichlorobenzene	4-dichlorobenzene results in increased expression of CYP2E1 protein	10696772
C018511	4-dichlorobenzene	[Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene	9051121
C024836	4-nitrophenol	4-nitrophenol binds to CYP2E1 protein	24924949
C024836	4-nitrophenol	4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]	10215755
C024836	4-nitrophenol	4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased oxidation of norflurane]	1356728
C024836	4-nitrophenol	Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
C024836	4-nitrophenol	Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136\|9143349
C024836	4-nitrophenol	Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136\|9143349
C024836	4-nitrophenol	Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	9143349
C024836	4-nitrophenol	CYP2E1 protein results in increased hydroxylation of 4-nitrophenol	14669323\|1513508
C024836	4-nitrophenol	CYP2E1 protein results in increased metabolism of 4-nitrophenol	12464242\|1557644
C024836	4-nitrophenol	CYP2E1 protein results in increased oxidation of 4-nitrophenol	10207612\|1121214
C024836	4-nitrophenol	Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
C024836	4-nitrophenol	Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
C024836	4-nitrophenol	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8074729\|8531136
C024836	4-nitrophenol	ferric-adenosine triphosphate complex inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
C024836	4-nitrophenol	fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
C024836	4-nitrophenol	IL6 protein promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
C024836	4-nitrophenol	Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
C024836	4-nitrophenol	Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136\|9143349
C024836	4-nitrophenol	Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
C024836	4-nitrophenol	CYP2E1 protein results in increased hydroxylation of 4-nitrophenol	10094576\|1574297
C024836	4-nitrophenol	2-(allylthio)pyrazine inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	9065729
C024836	4-nitrophenol	4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
C024836	4-nitrophenol	Acetone promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	8267643
C024836	4-nitrophenol	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153\|8117321
C024836	4-nitrophenol	Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153
C024836	4-nitrophenol	CYP2E1 protein results in increased hydroxylation of 4-nitrophenol	11408273\|1191184
C024836	4-nitrophenol	CYP2E1 protein results in increased metabolism of 4-nitrophenol	15763544\|2646327
C024836	4-nitrophenol	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	9618253
C024836	4-nitrophenol	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153
C024836	4-nitrophenol	phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153
C024836	4-nitrophenol	pyridine promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	9618253
C024836	4-nitrophenol	S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	15763544
C024836	4-nitrophenol	4-nitrophenol results in decreased activity of CYP2E1 protein	9877205
C016583	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	CYP2E1 protein affects the metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	12920169
C016583	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	12115524
C016583	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased activity of CYP2E1 protein	9774145
C016583	4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	CYP2E1 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone	25221795
C012606	4-vinyl-1-cyclohexene dioxide	CYP2E1 protein affects the susceptibility to 4-vinyl-1-cyclohexene dioxide	18622027
C012606	4-vinyl-1-cyclohexene dioxide	[CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene] which results in increased chemical synthesis of 4-vinyl-1-cyclohexene dioxide	22061827
C013733	4-vinylcyclohexene	4-vinylcyclohexene results in increased expression of CYP2E1 protein	9929517
C013733	4-vinylcyclohexene	CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene	11368546
C013733	4-vinylcyclohexene	"[CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene] which results in increased abundance of 1,2-epoxy-4-vinylcyclohexane"	11368546
C013733	4-vinylcyclohexene	CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene	22061827
C013733	4-vinylcyclohexene	[CYP2E1 protein results in increased metabolism of 4-vinylcyclohexene] which results in increased chemical synthesis of 4-vinyl-1-cyclohexene dioxide	22061827
C031286	4-xylene	CYP2E1 protein results in increased metabolism of 4-xylene	8558417
C031286	4-xylene	CYP2E1 protein results in increased oxidation of 4-xylene	17156750
C031286	4-xylene	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene]	8558417
C031286	4-xylene	4-xylene results in increased activity of CYP2E1 protein	12781212
C031286	4-xylene	Disulfiram inhibits the reaction [4-xylene results in increased activity of CYP2E1 protein]	12781212
C031286	4-xylene	CYP2E1 protein results in increased oxidation of 4-xylene	18247580
C040997	5-bromotryptamine	5-bromotryptamine analog results in decreased activity of CYP2E1 protein	26599973
C040997	5-bromotryptamine	[5-bromotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C529169	5-chlorotryptamine	5-chlorotryptamine analog results in decreased activity of CYP2E1 protein	26599973
C529169	5-chlorotryptamine	[5-chlorotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C051101	5-fluoro-alpha-methyltryptamine	5-fluoro-alpha-methyltryptamine results in decreased activity of CYP2E1 protein	26599973
C051101	5-fluoro-alpha-methyltryptamine	[5-fluoro-alpha-methyltryptamine results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C034536	5-fluorotryptamine	5-fluorotryptamine analog results in decreased activity of CYP2E1 protein	26599973
C034536	5-fluorotryptamine	[5-fluorotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C033696	5-methoxy-N,N-diisopropyltryptamine	"5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein"	26599973
C033696	5-methoxy-N,N-diisopropyltryptamine	"[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone"	26599973
C027552	5-methyltryptamine	5-methyltryptamine analog results in decreased activity of CYP2E1 protein	26599973
C027552	5-methyltryptamine	[5-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C010643	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]"	9143349
C039289	6-hydroxychlorzoxazone	CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone	12401345\|1515555
C039289	6-hydroxychlorzoxazone	CYP2E1 protein results in increased hydroxylation of 6-hydroxychlorzoxazone	19900514
C039289	6-hydroxychlorzoxazone	[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone	23669205
C039289	6-hydroxychlorzoxazone	Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]	23669205
C039289	6-hydroxychlorzoxazone	CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone	28438436
C039289	6-hydroxychlorzoxazone	[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone	28438436
C039289	6-hydroxychlorzoxazone	[Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazone	28438436
C073279	6-phenylhexyl isothiocyanate	6-phenylhexyl isothiocyanate results in decreased activity of CYP2E1 protein	10616189
C056033	7-ethoxy-4-trifluoromethylcoumarin	CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin	9241656
C056033	7-ethoxy-4-trifluoromethylcoumarin	Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]	9241656
C017299	7-ethoxycoumarin	CYP2E1 protein results in increased metabolism of 7-ethoxycoumarin	18385292
C084236	7-hydroxy-4-trifluoromethylcoumarin	CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin	9241656
C084236	7-hydroxy-4-trifluoromethylcoumarin	Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]	9241656
C031477	7-hydroxycoumarin	7-hydroxycoumarin inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein]	24661945
C540005	7-methoxy-4-trifluoromethylcoumarin	acetonitrile inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]	19858067
C540005	7-methoxy-4-trifluoromethylcoumarin	CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin	19858067
C540005	7-methoxy-4-trifluoromethylcoumarin	Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]	19858067
C036696	7-methyltryptamine	7-methyltryptamine analog results in decreased activity of CYP2E1 protein	26599973
C036696	7-methyltryptamine	[7-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C421010	9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole	"CYP2E1 protein results in increased chemical synthesis of 9-(4'-aminophenyl)-9H-pyrido(3,4-b)indole"	15279827
D020909	Acarbose	Acarbose results in decreased expression of CYP2E1 mRNA	14975757
C001969	acephate	[acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein	17686559
C001969	acephate	[fenarimol co-treated with acephate] affects the expression of CYP2E1 protein	17686559
C001969	acephate	[fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein	17686559
D000079	Acetaldehyde	CYP2E1 protein results in increased metabolism of Acetaldehyde	10826103
D000079	Acetaldehyde	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Acetaldehyde	18845238
D000079	Acetaldehyde	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde	7562599
D000079	Acetaldehyde	phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde]	7562599
D000082	Acetaminophen	Acetaminophen results in decreased expression of CYP2E1 mRNA	29067470
D000082	Acetaminophen	Acetaminophen results in decreased expression of CYP2E1 protein	29067470
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP2E1 mRNA	26690555
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP2E1 protein	23728527
D000082	Acetaminophen	[CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen	28762043
D000082	Acetaminophen	CYP2E1 protein results in increased metabolism of Acetaminophen	12464242\|1557644
D000082	Acetaminophen	CYP2E1 protein results in increased susceptibility to Acetaminophen	11212141\|2876204
D000082	Acetaminophen	Ethanol affects the reaction [CYP2E1 protein results in increased susceptibility to Acetaminophen]	11212141
D000082	Acetaminophen	GSTM1 protein inhibits the reaction [[CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen]	28762043
D000082	Acetaminophen	Acetaminophen affects the expression of CYP2E1 mRNA	17562736
D000082	Acetaminophen	Acetaminophen results in decreased activity of CYP2E1 protein	26772156
D000082	Acetaminophen	Acetaminophen results in decreased expression of CYP2E1 mRNA	15576447
D000082	Acetaminophen	Acetaminophen results in decreased expression of CYP2E1 protein	15576447\|2132937
D000082	Acetaminophen	Acetaminophen results in increased activity of CYP2E1 protein	19256530\|1979966
D000082	Acetaminophen	[Acetaminophen results in increased activity of CYP2E1 protein] inhibits the reaction [PPARA protein results in increased oxidation of Fatty Acids]	19256530
D000082	Acetaminophen	Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein	22939915
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP2E1 mRNA	12958197\|1639394
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP2E1 protein	19002106\|2006781
D000082	Acetaminophen	Carnosine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	19799668
D000082	Acetaminophen	[Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA	17585979
D000082	Acetaminophen	CYP2E1 protein affects the metabolism of and results in decreased abundance of Acetaminophen	19679878
D000082	Acetaminophen	CYP2E1 protein affects the reaction [Acetaminophen results in increased abundance of acylcarnitine]	19256530
D000082	Acetaminophen	CYP2E1 protein affects the reaction [Acetaminophen results in increased activity of PPARA protein]	19256530
D000082	Acetaminophen	CYP2E1 protein affects the susceptibility to Acetaminophen	19256530
D000082	Acetaminophen	CYP2E1 protein results in increased metabolism of Acetaminophen	19002106
D000082	Acetaminophen	CYP2E1 protein results in increased metabolism of and affects the susceptibility to Acetaminophen	11376689
D000082	Acetaminophen	CYP2E1 protein results in increased metabolism of and results in increased activity of Acetaminophen	25319358
D000082	Acetaminophen	CYP2E1 protein results in increased susceptibility to Acetaminophen	11323178\|1655755
D000082	Acetaminophen	dioscin inhibits the reaction [Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein]	22939915
D000082	Acetaminophen	Genistein inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	23333575
D000082	Acetaminophen	hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein]	26772156
D000082	Acetaminophen	IL1A protein inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	19002106
D000082	Acetaminophen	KITL protein inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]	12594235
D000082	Acetaminophen	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA]	17585979
D000082	Acetaminophen	PPARA protein affects the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]	12958197
D000082	Acetaminophen	S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein]	22683606
D000082	Acetaminophen	schizandrol B inhibits the reaction [CYP2E1 protein results in increased metabolism of and results in increased activity of Acetaminophen]	25319358
D000082	Acetaminophen	SLC13A1 protein affects the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]	16729303
D000082	Acetaminophen	Taurine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	20166895
D000082	Acetaminophen	Taurine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	20067817
D000082	Acetaminophen	[Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA	17126469
D000082	Acetaminophen	Acetaminophen results in decreased expression of CYP2E1 mRNA	17126469\|2180707
D000082	Acetaminophen	Acetaminophen results in increased activity of CYP2E1 protein	19932728
D000082	Acetaminophen	Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein	21170329
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP2E1 protein	18798224
D000082	Acetaminophen	Acetaminophen results in increased phosphorylation of and results in increased activity of CYP2E1 protein	11562448
D000082	Acetaminophen	Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	19932728
D000082	Acetaminophen	Choline deficiency promotes the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	18798224
D000082	Acetaminophen	CYP2E1 protein affects the metabolism of Acetaminophen	15772367
D000082	Acetaminophen	CYP2E1 protein results in increased susceptibility to Acetaminophen	21130154
D000082	Acetaminophen	[Isoniazid results in increased expression of CYP2E1] which results in increased metabolism of Acetaminophen	20566340
D000082	Acetaminophen	Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]	17126469
D000082	Acetaminophen	YH 439 inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of CYP2E1 protein]	11562448
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP2E1 protein	20166895
D000082	Acetaminophen	Buthionine Sulfoximine promotes the reaction [CYP2E1 protein affects the oxidation of Acetaminophen]	20404090
D000082	Acetaminophen	CYP2E1 protein affects the metabolism of and results in decreased abundance of Acetaminophen	20166895
D000082	Acetaminophen	CYP2E1 protein affects the oxidation of Acetaminophen	20404090
D000082	Acetaminophen	CYP2E1 protein results in increased metabolism of Acetaminophen	20423716\|2362845
D000082	Acetaminophen	CYP2E1 results in increased metabolism of Acetaminophen	20566340
D000082	Acetaminophen	Taurine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	20166895
D019342	Acetic Acid	CYP2E1 protein results in increased metabolism of Acetic Acid analog	21933969
D000096	Acetone	CYP2E1 protein results in increased metabolism of Acetone	15576447
D000096	Acetone	[Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene	8560479
D000096	Acetone	Acetone results in increased expression of and results in increased activity of CYP2E1 protein	8013281
D000096	Acetone	Acetone results in increased expression of CYP2E1 protein	18990727
D000096	Acetone	[Acetone results in increased expression of CYP2E1 protein] which results in increased susceptibility to allyl cyanide	18990727
D000096	Acetone	Acetone results in increased activity of CYP2E1 protein	8471070
D000096	Acetone	Acetone results in increased expression of CYP2E1 mRNA	8471070
D000096	Acetone	Acetone results in increased expression of CYP2E1 protein	8471070
D000096	Acetone	Alpha-Amanitin inhibits the reaction [Acetone results in increased expression of CYP2E1 mRNA]	8471070
D000096	Acetone	"1,2-dichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein]"	9851676
D000096	Acetone	[Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein	7587954
D000096	Acetone	[Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA	8734847
D000096	Acetone	[Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein	8734847
D000096	Acetone	[Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein	8734847
D000096	Acetone	[Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein	8734847
D000096	Acetone	Acetone promotes the reaction [2-xylene results in increased expression of CYP2E1 protein]	8996725
D000096	Acetone	Acetone promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	8267643
D000096	Acetone	Acetone promotes the reaction [Toluene results in increased expression of CYP2E1 protein]	8996725
D000096	Acetone	Acetone results in increased activity of CYP2E1 protein	12919724\|2012731
D000096	Acetone	Acetone results in increased expression of CYP2E1 mRNA	11939710\|2241968
D000096	Acetone	Acetone results in increased expression of CYP2E1 protein	11939710\|1291972
D000096	Acetone	Trichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein]	9851676
D000096	Acetone	Acetone results in increased activity of CYP2E1 protein	8560479
C032159	acetonitrile	acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C032159	acetonitrile	acetonitrile inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]	19858067
D000111	Acetylcysteine	[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]	21424224
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]	23159886
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	23159886
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]	23159886
D000111	Acetylcysteine	Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]	26332274
D000111	Acetylcysteine	[CYP2E1 protein co-treated with Acetylcysteine] affects the metabolism of Isoquinolines	21395287
D020106	Acrylamide	Acrylamide affects the expression of CYP2E1 mRNA	17267090
D020106	Acrylamide	Acrylamide results in increased expression of CYP2E1 protein	24508477
D020106	Acrylamide	Curcumin inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein]	24508477
D020106	Acrylamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the metabolism of Acrylamide	19131562
D020106	Acrylamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Acrylamide	19131562
D020106	Acrylamide	CYP2E1 protein affects the susceptibility to Acrylamide	24508477
D020106	Acrylamide	epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein]	24508477
D020106	Acrylamide	CYP2E1 protein affects the metabolism of Acrylamide	17979661
D020106	Acrylamide	CYP2E1 protein results in increased oxidation of Acrylamide	15355880
D020106	Acrylamide	[CYP2E1 protein results in increased oxidation of Acrylamide] which results in increased abundance of glycidamide	27174446
D020106	Acrylamide	CYP2E1 protein results in increased susceptibility to Acrylamide	15355880\|1726709
D020106	Acrylamide	Acrylamide affects the expression of CYP2E1 mRNA	28959563
D020106	Acrylamide	Acrylamide results in increased expression of CYP2E1 mRNA	28606764
D020106	Acrylamide	CYP2E1 protein affects the metabolism of Acrylamide	21978862
D020106	Acrylamide	CYP2E1 protein results in increased metabolism of Acrylamide	25980586\|2678300
D020106	Acrylamide	[CYP2E1 protein results in increased metabolism of Acrylamide] which results in increased chemical synthesis of glycidamide	25980586
D000181	Acrylonitrile	CYP2E1 protein results in increased oxidation of Acrylonitrile	1664256
D000181	Acrylonitrile	Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]	26332274
D000181	Acrylonitrile	Acrylonitrile inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene]	9010585
D000181	Acrylonitrile	Acrylonitrile results in increased expression of CYP2E1 mRNA	26332274
D000181	Acrylonitrile	alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]	26332274
D000181	Acrylonitrile	CYP2E1 protein affects the susceptibility to Acrylonitrile	20127315
D000181	Acrylonitrile	Plant Extracts promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]	26332274
C058956	acteoside	acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein]	14672760
C116917	acylcarnitine	CYP2E1 protein affects the reaction [Acetaminophen results in increased abundance of acylcarnitine]	19256530
D012436	S-Adenosylmethionine	S-Adenosylmethionine results in decreased activity of CYP2E1 protein	15763544
D012436	S-Adenosylmethionine	S-Adenosylmethionine inhibits the reaction [Acetaminophen results in decreased expression of CYP2E1 protein]	22683606
D012436	S-Adenosylmethionine	S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein]	15983038
D012436	S-Adenosylmethionine	S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	15763544
D012436	S-Adenosylmethionine	S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	15763544
D012436	S-Adenosylmethionine	S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Ethanol]	15763544
D012436	S-Adenosylmethionine	S-Adenosylmethionine results in decreased activity of CYP2E1 protein	15763544
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of CYP2E1 protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of CYP2E1 mRNA	22100608\|2715375
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of CYP2E1 mRNA	19770486
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of CYP2E1 mRNA	23630614
D016604	Aflatoxin B1	CYP2E1 protein results in increased oxidation of Aflatoxin B1	25154877
D016604	Aflatoxin B1	"[CYP2E1 protein results in increased oxidation of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin B1-2,3-oxide"	25154877
C006426	aflatoxin B1-2,3-oxide	"CYP2E1 protein results in increased chemical synthesis of aflatoxin B1-2,3-oxide"	25154877
C006426	aflatoxin B1-2,3-oxide	"[CYP2E1 protein results in increased oxidation of Aflatoxin B1] which results in increased chemical synthesis of aflatoxin B1-2,3-oxide"	25154877
D000438	Alcohols	Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA]	24025710
D000438	Alcohols	Alcohols results in increased activity of CYP2E1 protein	24025710
D000438	Alcohols	Alcohols results in increased expression of CYP2E1 mRNA	24025710
D000438	Alcohols	ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA]	24025710
D000438	Alcohols	Alcohols results in increased expression of CYP2E1 protein	28803762
D000438	Alcohols	Apigenin inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein]	28803762
D000438	Alcohols	Glutathione inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein]	28803762
C010078	alizarin	alizarin results in decreased activity of CYP2E1 protein	12379470
D000470	Alkaloids	Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	21224420
D000470	Alkaloids	Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	21224420
D000487	Allethrin	Allethrin results in increased expression of and results in increased activity of CYP2E1 protein	22080754
D000496	Alloxan	Alloxan affects the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	17034923
D000496	Alloxan	Alloxan results in increased expression of CYP2E1 protein	17034923
C006463	allyl alcohol	allyl alcohol results in increased expression of CYP2E1 protein	11515535
C015660	allyl cyanide	[Acetone results in increased expression of CYP2E1 protein] which results in increased susceptibility to allyl cyanide	18990727
C015660	allyl cyanide	CYP2E1 protein results in increased susceptibility to allyl cyanide	22051853
C077207	allyl methyl sulfide	allyl methyl sulfide results in decreased expression of CYP2E1 protein	16000231\|8117321
C038491	allyl sulfide	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]	12086689
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	22138249
C038491	allyl sulfide	allyl sulfide results in decreased activity of CYP2E1 protein	15974642\|1703478
C038491	allyl sulfide	allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]	21684301
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	22138249
C038491	allyl sulfide	allyl sulfide inhibits the reaction [ethylene dichloride results in increased expression of CYP2E1 protein]	27301210
C038491	allyl sulfide	"allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 2,2-dichloro-1,1,1-trifluoroethane]"	7956723
C038491	allyl sulfide	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153\|8117321
C038491	allyl sulfide	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline]	8117321
C038491	allyl sulfide	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
C038491	allyl sulfide	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	8117321
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP2E1 protein]	23494807
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2E1 mRNA]	23494807
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	20116195
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein]	8117321
C038491	allyl sulfide	allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein]	8117321
C038491	allyl sulfide	allyl sulfide results in decreased activity of CYP2E1 protein	7956723
C038491	allyl sulfide	allyl sulfide results in decreased expression of CYP2E1 protein	16000231\|7601153
C038491	allyl sulfide	allyl sulfide results in increased activity of CYP2E1 protein	15046820
C038491	allyl sulfide	allyl sulfide results in increased expression of CYP2E1 protein	8627517
C038491	allyl sulfide	allyl sulfide results in decreased activity of CYP2E1 protein	12060674\|1208668
D053959	Alpha-Amanitin	Alpha-Amanitin inhibits the reaction [Acetone results in increased expression of CYP2E1 mRNA]	8471070
C010177	alpha-hederin	alpha-hederin results in decreased activity of CYP2E1 protein	9861456
C040534	alpha-hexachlorocyclohexane	[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein	16246485
D017962	alpha-Linolenic Acid	alpha-Linolenic Acid results in decreased activity of CYP2E1 protein	16978661
D024502	alpha-Tocopherol	alpha-Tocopherol results in increased expression of CYP2E1 mRNA	28062356
D024502	alpha-Tocopherol	alpha-Tocopherol promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]	26332274
D024502	alpha-Tocopherol	alpha-Tocopherol results in increased expression of CYP2E1 mRNA	26332274
D024502	alpha-Tocopherol	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D024502	alpha-Tocopherol	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D000638	Amiodarone	CYP2E1 protein results in decreased susceptibility to Amiodarone	26477383
D000640	Amitrole	Amitrole results in decreased activity of CYP2E1 protein	12464242
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of CYP2E1 mRNA	16483693
D000728	Androgens	Androgens results in decreased expression of CYP2E1 protein	2785912
D000737	Androstenols	Androstenols results in decreased expression of CYP2E1 mRNA	17962186
C011659	angelicin	angelicin results in decreased expression of CYP2E1 protein	22173200
C023650	aniline	aniline results in decreased activity of CYP2E1 protein	12814958\|1530620
C023650	aniline	CYP2E1 protein affects the metabolism of [norharman co-treated with aniline]	15279827
C023650	aniline	CYP2E1 protein results in increased hydroxylation of aniline	8858968\|9195021
C023650	aniline	CYP2E1 protein results in increased metabolism of aniline	12464242\|8819299
C023650	aniline	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of aniline]	8074729
C023650	aniline	Proadifen inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline]	8819299
C023650	aniline	CYP2E1 protein results in increased hydroxylation of aniline	9195021
C023650	aniline	caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	18436364
C023650	aniline	Changkil inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	18291569
C023650	aniline	CYP2E1 protein results in increased hydroxylation of aniline	18038910\|1829156
C023650	aniline	puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	18038910
C023650	aniline	[CYP2E1 protein co-treated with POR protein] results in increased hydroxylation of aniline	2292581
C023650	aniline	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline]	8117321
C023650	aniline	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of aniline	9010585
C023650	aniline	CYP2E1 protein results in increased hydroxylation of aniline	23274713
C023650	aniline	CYP2E1 protein results in increased metabolism of aniline	26463279
C023650	aniline	Ethanol promotes the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	23274713
C023650	aniline	Genistein inhibits the reaction [Ethanol promotes the reaction [CYP2E1 protein results in increased hydroxylation of aniline]]	23274713
C023650	aniline	[Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein] which results in decreased hydroxylation of aniline	11330834
D000872	Anthocyanins	Anthocyanins results in increased expression of CYP2E1 mRNA	18803703
D047310	Apigenin	Apigenin inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein]	28803762
D016718	Arachidonic Acid	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]	12086689
D016718	Arachidonic Acid	[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein	17034788
D016718	Arachidonic Acid	[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein	17034788
D016718	Arachidonic Acid	[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein	17034788
D016718	Arachidonic Acid	Arachidonic Acid results in decreased activity of CYP2E1 protein	16978661
D016718	Arachidonic Acid	Cadmium Chloride affects the reaction [CYP2E1 protein results in increased susceptibility to Arachidonic Acid]	12566070
D016718	Arachidonic Acid	CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]	12086689\|2135282
D016718	Arachidonic Acid	CYP2E1 results in increased susceptibility to Arachidonic Acid	12566070
D016718	Arachidonic Acid	CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate]	12566070
D016718	Arachidonic Acid	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]	12086689
D016718	Arachidonic Acid	"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]"	12086689
D016718	Arachidonic Acid	Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Arachidonic Acid]	12566070
D016718	Arachidonic Acid	CYP2E1 protein affects the hydroxylation of Arachidonic Acid	15205388
D001115	Arecoline	Arecoline analog results in increased activity of CYP2E1 protein	25056785
D001151	Arsenic	Arsenic affects the expression of CYP2E1 mRNA	18414638
D001151	Arsenic	Arsenic inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	19932728
D001151	Arsenic	Arsenic results in decreased activity of CYP2E1 protein	19932728
C006632	arsenic trioxide	arsenic trioxide affects the expression of CYP2E1 mRNA	17530438
C031327	artemisinine	artemisinine results in increased expression of CYP2E1 mRNA	17962186
D017636	Asbestos, Amphibole	"Asbestos, Amphibole affects the expression of CYP2E1 protein"	20855422
D001205	Ascorbic Acid	[Ascorbic Acid co-treated with Ethanol] results in decreased expression of CYP2E1 mRNA	22149461
D001205	Ascorbic Acid	Ascorbic Acid results in decreased activity of CYP2E1 protein	17512695
C017032	asiatic acid	"asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in increased activity of CYP2E1 protein]"	29108773
C022870	asoxime chloride	asoxime chloride results in decreased activity of CYP2E1 protein	19539805
D001218	Aspartame	Aspartame results in increased expression of and results in increased activity of CYP2E1 protein	16937917
D001241	Aspirin	Aspirin results in increased expression of CYP2E1 mRNA	11752103
D001280	Atrazine	Atrazine results in increased expression of CYP2E1 mRNA	26775023
D001280	Atrazine	lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]	26775023
D001280	Atrazine	Atrazine results in increased expression of CYP2E1 protein	14961354
C547126	AZM551248	AZM551248 results in increased expression of CYP2E1 mRNA	22323515
D001397	Azoxymethane	Azoxymethane results in decreased expression of CYP2E1 mRNA	18038451
C447119	bazedoxifene	CYP2E1 protein results in increased glutathionylation of bazedoxifene	22429462
C030935	benz(a)anthracene	benz(a)anthracene results in increased expression of CYP2E1 mRNA	26377693
D001554	Benzene	Benzene results in decreased methylation of CYP2E1 promoter	28823944
D001554	Benzene	Benzene results in increased expression of CYP2E1 mRNA	18952161
D001554	Benzene	CYP2E1 gene polymorphism affects the susceptibility to Benzene	15226677\|1673758
D001554	Benzene	CYP2E1 gene polymorphism results in increased susceptibility to Benzene	15226677
D001554	Benzene	CYP2E1 gene SNP affects the susceptibility to Benzene	21784317
D001554	Benzene	CYP2E1 protein affects the metabolism of Benzene	15051535\|1522667
D001554	Benzene	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol	15051535
D001554	Benzene	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone	15051535
D001554	Benzene	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone	15051535
D001554	Benzene	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of muconic acid	15051535
D001554	Benzene	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of Phenol	15051535
D001554	Benzene	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of S-phenyl-N-acetylcysteine	15051535
D001554	Benzene	CYP2E1 protein affects the susceptibility to Benzene	12460800\|8987251
D001554	Benzene	CYP2E1 protein alternative form results in increased hydroxylation of Benzene	20033806
D001554	Benzene	CYP2E1 protein results in increased hydroxylation of Benzene	15122651\|2003380
D001554	Benzene	CYP2E1 protein results in increased metabolism of Benzene	17885617\|1835091
D001554	Benzene	CYP2E1 protein results in increased oxidation of Benzene	10207612\|1664256
D001554	Benzene	[Acetone results in increased activity of CYP2E1 protein] which results in increased oxidation of Benzene	8560479
D001554	Benzene	AHR protein affects the reaction [Benzene results in increased expression of CYP2E1 protein]	12388843
D001554	Benzene	Benzene results in decreased activity of CYP2E1 protein	8751834
D001554	Benzene	[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene	9817075
D001554	Benzene	Benzene results in increased expression of CYP2E1 mRNA	12928149\|1715716
D001554	Benzene	Benzene results in increased expression of CYP2E1 protein	12388843
D001554	Benzene	CYP2E1 protein affects the susceptibility to Benzene	8560479
D001554	Benzene	CYP2E1 protein results in increased hydroxylation of Benzene	11718959\|1471817
D001554	Benzene	CYP2E1 protein results in increased metabolism of Benzene	11376689\|8461037
D001554	Benzene	CYP2E1 protein results in increased oxidation of Benzene	8560479
D001554	Benzene	CYP2E1 protein results in increased susceptibility to Benzene	8917693
D001554	Benzene	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]	9817075
D001554	Benzene	[Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene	8560479
D001554	Benzene	[Toluene co-treated with Benzene] results in increased activity of CYP2E1 protein	18455711
D001554	Benzene	CYP2E1 protein results in increased metabolism of Benzene	3416296
D001554	Benzene	Acrylonitrile inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene]	9010585
D001554	Benzene	Benzene affects the expression of CYP2E1 mRNA	15878777
D001554	Benzene	Benzene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]	8889796
D001554	Benzene	Benzene results in decreased activity of CYP2E1 protein	18407866
D001554	Benzene	Benzene results in decreased expression of CYP2E1 protein	15274493
D001554	Benzene	Benzene results in increased activity of CYP2E1 protein	12919724\|2033886
D001554	Benzene	[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene	9817075
D001554	Benzene	[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene	9817075
D001554	Benzene	Benzene results in increased expression of CYP2E1 mRNA	12919724
D001554	Benzene	Benzene results in increased expression of CYP2E1 protein	12919724\|3416296
D001554	Benzene	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of aniline	9010585
D001554	Benzene	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene	9010585
D001554	Benzene	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of chlorobenzene	9010585
D001554	Benzene	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Toluene	9010585
D001554	Benzene	CYP2E1 protein affects the reaction [Benzene results in increased metabolism of Toluene]	8620572
D001554	Benzene	CYP2E1 protein affects the susceptibility to Benzene	9118891
D001554	Benzene	CYP2E1 protein results in increased metabolism of Benzene	1739413\|3416296\|
D001554	Benzene	[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone	8211999
D001554	Benzene	[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol	8211999
D001554	Benzene	CYP2E1 protein results in increased oxidation of Benzene	9118895
D001554	Benzene	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]	9817075
D001554	Benzene	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene]	9817075
D001554	Benzene	Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene]	9010585
D001554	Benzene	EPHX1 protein promotes the reaction [CYP2E1 protein results in increased metabolism of Benzene]	8211999
D001554	Benzene	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Benzene metabolite]	8211999
D001554	Benzene	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]	8211999
D001554	Benzene	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol]	8211999
D001554	Benzene	Melatonin inhibits the reaction [Benzene results in increased activity of CYP2E1 protein]	20338863
D001554	Benzene	[Methylcholanthrene results in decreased expression of CYP2E1 protein] which affects the metabolism of Benzene	9118891
D001554	Benzene	Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein]	18407866
D001554	Benzene	CYP2E1 protein affects the metabolism of Benzene	10447556
D001554	Benzene	CYP2E1 protein results in increased metabolism of Benzene	15833037
C006703	benzo(b)fluoranthene	benzo(b)fluoranthene results in increased expression of CYP2E1 mRNA	16269432
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in decreased expression of CYP2E1 mRNA	22258563
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP2E1 mRNA	19969063
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP2E1 mRNA	16269432
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased mutagenesis of CYP2E1 gene	25435355
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of CYP2E1 mRNA	19770486\|2012785
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP2E1 mRNA	19889059\|2138358
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP2E1 protein	19889059\|2138358
D001589	Benzphetamine	[CYP2E1 protein co-treated with POR protein] results in decreased methylation of Benzphetamine	2292581
D019905	Benzyl Alcohol	CYP2E1 protein affects the metabolism of Benzyl Alcohol	8592870
D001592	Benzyl Alcohols	CYP2E1 protein results in increased oxidation of Benzyl Alcohols	7515681
C025383	benzylideneacetone	CYP2E1 protein results in increased oxidation of benzylideneacetone	15863696
D001599	Berberine	Berberine inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	25455889
D001599	Berberine	Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA]	22342832
D001599	Berberine	Berberine results in decreased expression of CYP2E1 mRNA	22342832
D004958	Estradiol	Estradiol results in decreased expression of CYP2E1 mRNA	20106945
D004958	Estradiol	Estradiol results in increased activity of CYP2E1 protein	22837389
D004958	Estradiol	Estradiol results in decreased expression of CYP2E1 mRNA	19484750
D004958	Estradiol	[Estradiol co-treated with Plant Preparations] results in decreased expression of CYP2E1 mRNA	26945725
D001622	Betaine	Betaine promotes the reaction [Ethanol results in increased expression of CYP2E1]	21352821
D001622	Betaine	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
C095105	bexarotene	bexarotene analog results in increased expression of CYP2E1 mRNA	28689802
C477843	bicyclol	bicyclol inhibits the reaction [Tetracycline results in decreased expression of CYP2E1 mRNA]	19427351
C477843	bicyclol	bicyclol results in increased activity of CYP2E1 protein	15998439
C099952	bifenthrin	bifenthrin results in increased expression of CYP2E1 mRNA	26071804
C073710	bilobalide	bilobalide results in increased activity of CYP2E1 protein	18421621
D001710	Biotin	Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C006780	bisphenol A	CYP2E1 protein results in increased glutathionylation of bisphenol A metabolite	23470418
C006780	bisphenol A	CYP2E1 protein results in increased hydroxylation of bisphenol A	23470418
C006780	bisphenol A	CYP2E1 protein results in increased hydroxylation of bisphenol A metabolite	23470418
C006780	bisphenol A	CYP2E1 protein results in increased susceptibility to bisphenol A	27491884
C006780	bisphenol A	bisphenol A results in increased methylation of CYP2E1 promoter	27312807
C006780	bisphenol A	[LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA	28123100
C006780	bisphenol A	bisphenol A affects the expression of CYP2E1 mRNA	25181051
C006780	bisphenol A	bisphenol A results in decreased expression of CYP2E1 mRNA	26794494
D001786	Blood Glucose	Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D001786	Blood Glucose	Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D001786	Blood Glucose	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA]	26747958
D001786	Blood Glucose	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein]	26747958
D001786	Blood Glucose	Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D001786	Blood Glucose	Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D001786	Blood Glucose	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA	26747958
D001786	Blood Glucose	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 protein	26747958
D001786	Blood Glucose	[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA	26747958
D001786	Blood Glucose	[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein	26747958
D001786	Blood Glucose	[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA	26747958
D001786	Blood Glucose	[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein	26747958
D001786	Blood Glucose	zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D001786	Blood Glucose	zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
C021636	bromadiolone	bromadiolone results in increased expression of CYP2E1 mRNA	18080289
C021636	bromadiolone	CYP2E1 protein results in decreased susceptibility to bromadiolone	18080289
C032036	bromobenzene	bromobenzene results in increased expression of CYP2E1 protein	10547960
C032036	bromobenzene	bromobenzene results in increased expression of CYP2E1 mRNA	12628495
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP2E1 mRNA	22079614
C025191	bromodichloromethane	CYP2E1 protein results in increased metabolism of bromodichloromethane	12076521\|1207652
C025191	bromodichloromethane	CYP2E1 gene mutant form results in decreased susceptibility to bromodichloromethane	23640861
C025191	bromodichloromethane	CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IFNG mRNA]	24211274
C025191	bromodichloromethane	CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL1B mRNA]	24211274
C025191	bromodichloromethane	CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]	24211274
C025191	bromodichloromethane	CYP2E1 protein affects the susceptibility to [bromodichloromethane co-treated with Dietary Fats]	24211274
C025191	bromodichloromethane	[Dietary Fats co-treated with bromodichloromethane] results in increased expression of CYP2E1 protein	23438451
C025191	bromodichloromethane	bromodichloromethane results in increased expression of CYP2E1 protein	11295256
C025191	bromodichloromethane	CYP2E1 protein results in increased metabolism of and results in increased activity of bromodichloromethane	9458004
C025191	bromodichloromethane	CYP2E1 protein results in increased metabolism of bromodichloromethane	11295256\|1207652
C025191	bromodichloromethane	CYP2E1 protein results in increased metabolism of bromodichloromethane	23438451
C025191	bromodichloromethane	[CYP2E1 protein results in increased metabolism of bromodichloromethane] which results in increased expression of LEP protein	23438451
C083806	brucine	[brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein	21800547
C083806	brucine	[brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein	21800547
C083806	brucine	brucine results in increased activity of CYP2E1 protein	21800547
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine promotes the reaction [CYP2E1 protein results in increased expression of COL1A2 mRNA]	10498651
D019328	Buthionine Sulfoximine	CYP2E1 protein results in increased susceptibility to Buthionine Sulfoximine	12086689
D019328	Buthionine Sulfoximine	CYP2E1 results in increased susceptibility to Buthionine Sulfoximine	12566070
D019328	Buthionine Sulfoximine	"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin promotes the reaction [CYP2E1 protein results in increased susceptibility to Buthionine Sulfoximine]"	12086689
D019328	Buthionine Sulfoximine	Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Buthionine Sulfoximine]	12566070
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine promotes the reaction [CYP2E1 protein affects the oxidation of Acetaminophen]	20404090
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in decreased activity of CYP2E1 protein	27432241
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein]	15379534
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form]	15379534
C038091	butylparaben	butylparaben results in decreased activity of CYP2E1 protein	27432241
D002104	Cadmium	Cadmium results in increased expression of CYP2E1 mRNA	21120746
D019256	Cadmium Chloride	Cadmium Chloride affects the reaction [CYP2E1 protein results in increased susceptibility to Arachidonic Acid]	12566070
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of CYP2E1 mRNA	11958953
C053400	cafestol	cafestol results in decreased activity of CYP2E1 protein	17590492
C040048	caffeic acid	caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C055494	caffeic acid phenethyl ester	caffeic acid phenethyl ester inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	18436364
C055494	caffeic acid phenethyl ester	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA	20360939
D002110	Caffeine	CYP2E1 protein affects the metabolism of Caffeine	1302044\|14586387
D002118	Calcium	CYP2E1 protein results in decreased uptake of Calcium	19028543
D002118	Calcium	Calcium affects the expression of CYP2E1 mRNA	15913539
C004645	canadine	canadine results in increased expression of CYP2E1 mRNA	28257954
C004645	canadine	canadine results in increased expression of CYP2E1 protein	28257954
D002211	Capsaicin	Capsaicin results in increased expression of CYP2E1	22375877
D002220	Carbamazepine	Carbamazepine results in decreased expression of CYP2E1 mRNA	17381134
D012721	Carbaryl	Carbaryl inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D012721	Carbaryl	Carbaryl results in decreased activity of CYP2E1 protein	22634058
D002248	Carbon Monoxide	Carbon Monoxide results in decreased activity of CYP2E1 protein	15036350
D002248	Carbon Monoxide	Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]	1903091
D002251	Carbon Tetrachloride	Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136\|9143349
D002251	Carbon Tetrachloride	Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased activity of CYP2E1 protein	17710613
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased degradation of and results in decreased activity of CYP2E1 protein	8531136
D002251	Carbon Tetrachloride	Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]	8531136
D002251	Carbon Tetrachloride	CYP2E1 protein results in increased metabolism of Carbon Tetrachloride	15797236\|1835091
D002251	Carbon Tetrachloride	Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D002251	Carbon Tetrachloride	Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]	8531136
D002251	Carbon Tetrachloride	Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D002251	Carbon Tetrachloride	fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D002251	Carbon Tetrachloride	fomepizole inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]	8531136
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased activity of CYP2E1 protein	17038628\|1979334
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein	15983038
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA	12759355\|1505680
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of CYP2E1 protein	12466116\|1596232
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased activity of CYP2E1 protein	25445725
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein	10355542
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of CYP2E1 protein	17610925\|2327984
D002251	Carbon Tetrachloride	CDKN1A protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]	12759355
D002251	Carbon Tetrachloride	CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of BNIP3 mRNA]	17084009
D002251	Carbon Tetrachloride	CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of CAR3 mRNA]	17084009
D002251	Carbon Tetrachloride	CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP1A2 mRNA]	17084009
D002251	Carbon Tetrachloride	CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of IL1RAP mRNA]	17084009
D002251	Carbon Tetrachloride	CYP2E1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in decreased expression of PAH mRNA]	17084009
D002251	Carbon Tetrachloride	CYP2E1 protein affects the susceptibility to Carbon Tetrachloride	15962327
D002251	Carbon Tetrachloride	Flavonoids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	23279844
D002251	Carbon Tetrachloride	ginsan promotes the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	19913046
D002251	Carbon Tetrachloride	Lipids inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]	25445725
D002251	Carbon Tetrachloride	Ly-364947 inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]	25566828
D002251	Carbon Tetrachloride	Ly-364947 inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	25566828
D002251	Carbon Tetrachloride	myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	25656916
D002251	Carbon Tetrachloride	NUPR1 protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]	15962327
D002251	Carbon Tetrachloride	NUPR1 protein affects the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	15962327
D002251	Carbon Tetrachloride	Oleanolic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein]	10355542
D002251	Carbon Tetrachloride	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	23279844\|2399409
D002251	Carbon Tetrachloride	Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	26218279
D002251	Carbon Tetrachloride	rossicaside B inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein]	19793341
D002251	Carbon Tetrachloride	S-Adenosylmethionine promotes the reaction [Carbon Tetrachloride results in decreased expression of and results in decreased activity of CYP2E1 protein]	15983038
D002251	Carbon Tetrachloride	Saponins inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	23994094
D002251	Carbon Tetrachloride	Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]	1903091
D002251	Carbon Tetrachloride	acteoside inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein]	14672760
D002251	Carbon Tetrachloride	Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	21224420
D002251	Carbon Tetrachloride	Alkaloids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	21224420
D002251	Carbon Tetrachloride	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of CYP2E1 mRNA	17805973
D002251	Carbon Tetrachloride	Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]	1903091
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased activity of CYP2E1 protein	14706259\|1628878
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA	14706259\|2545023
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased expression of CYP2E1 protein	17606319\|2545023
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased activity of CYP2E1 protein	17710613\|2589950
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased degradation of CYP2E1 protein	12679053
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein	14672760
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of CYP2E1 mRNA	11903743\|2122442
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of CYP2E1 protein	21224420
D002251	Carbon Tetrachloride	Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
D002251	Carbon Tetrachloride	crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]	25899501
D002251	Carbon Tetrachloride	CYP2E1 protein affects the metabolism of Carbon Tetrachloride	15772367
D002251	Carbon Tetrachloride	CYP2E1 protein results in increased metabolism of Carbon Tetrachloride	7601153
D002251	Carbon Tetrachloride	"Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]"	24582681
D002251	Carbon Tetrachloride	ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	11903743
D002251	Carbon Tetrachloride	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
D002251	Carbon Tetrachloride	isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]	25450236
D002251	Carbon Tetrachloride	isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	25450236
D002251	Carbon Tetrachloride	phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
D002251	Carbon Tetrachloride	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	21224420
D002251	Carbon Tetrachloride	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	21224420
D002251	Carbon Tetrachloride	Propolis inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein]	17410408
D002251	Carbon Tetrachloride	Silymarin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein]	17410408
D002251	Carbon Tetrachloride	Silymarin inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	24582681
D002251	Carbon Tetrachloride	CYP2E1 protein results in increased metabolism of and results in increased activity of Carbon Tetrachloride	16142352
D002251	Carbon Tetrachloride	CYP2E1 protein results in increased metabolism of Carbon Tetrachloride	15962327
D002251	Carbon Tetrachloride	[CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] which results in increased abundance of trichloromethyl free radical	19336974
D002331	Carnitine	Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein]	8130774
D002336	Carnosine	Carnosine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	19799668
D002392	Catechin	[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CYP2E1 mRNA	24763279
D002392	Catechin	Catechin inhibits the reaction [Ethanol results in increased expression of CYP2E1]	21352821
C034221	catechol	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of catechol	15051535
C034221	catechol	[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol	8211999
C034221	catechol	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol]	8211999
C088453	Celsior	Celsior results in decreased activity of CYP2E1 protein	15448115
C088453	Celsior	Celsior results in decreased expression of CYP2E1 mRNA	15448115
C440574	Changkil	Changkil inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	18291569
D002635	Chenodeoxycholic Acid	Chenodeoxycholic Acid results in decreased expression of CYP2E1 mRNA	27174168
C473711	Chir 99021	Chir 99021 results in increased expression of and results in increased activity of CYP2E1 protein	26259606
C473711	Chir 99021	Chir 99021 results in increased expression of CYP2E1 mRNA	26259606
D002697	Chloral Hydrate	CYP2E1 protein results in increased chemical synthesis of Chloral Hydrate	1739413
D002697	Chloral Hydrate	[CYP2E1 protein results in increased metabolism of Trichloroethylene] which results in increased chemical synthesis of Chloral Hydrate	1739413
D005023	Ethylene Chlorohydrin	[CYP2E1 protein results in increased metabolism of Vinyl Chloride] which results in increased abundance of Ethylene Chlorohydrin	26962056
C057223	chlorfluazuron	chlorfluazuron inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
C057223	chlorfluazuron	chlorfluazuron results in decreased activity of CYP2E1 protein	22634058
D002719	Chlormethiazole	Chlormethiazole inhibits the reaction [Docosahexaenoic Acids results in increased expression of CYP2E1 protein]	16963249
D002719	Chlormethiazole	Chlormethiazole results in decreased activity of CYP2E1 protein	26599973
D002719	Chlormethiazole	[Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002719	Chlormethiazole	Chlormethiazole results in decreased expression of CYP2E1 protein	16963249
D002719	Chlormethiazole	Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]	21684301
D002719	Chlormethiazole	Chlormethiazole inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	22552773
D002719	Chlormethiazole	Chlormethiazole inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24892905
D002719	Chlormethiazole	Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153
D002719	Chlormethiazole	Chlormethiazole inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
D002719	Chlormethiazole	Chlormethiazole results in decreased activity of CYP2E1 protein	16330492
D002719	Chlormethiazole	Chlormethiazole results in decreased expression of CYP2E1 mRNA	10751552
D002719	Chlormethiazole	Chlormethiazole results in decreased expression of CYP2E1 protein	10751552\|7601153
D002719	Chlormethiazole	Chlormethiazole results in decreased activity of CYP2E1 protein	16054987
C031294	chlorobenzene	CYP2E1 protein results in increased oxidation of chlorobenzene	9817075
C031294	chlorobenzene	dihydroxyethyldithiocarbamate inhibits the reaction [CYP2E1 protein results in increased metabolism of chlorobenzene]	9817075
C031294	chlorobenzene	[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene	9817075
C031294	chlorobenzene	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of chlorobenzene	9010585
C031294	chlorobenzene	CYP2E1 protein results in increased oxidation of chlorobenzene	9817075
C031294	chlorobenzene	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene]	9817075
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA	17851650
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 mRNA	8471063
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP2E1 protein	3113478
D002725	Chloroform	CYP2E1 gene SNP results in increased susceptibility to Chloroform	15289170
D002725	Chloroform	CYP2E1 protein results in increased metabolism of Chloroform	18350910
D002725	Chloroform	CYP2E1 protein results in increased oxidation of Chloroform	1664256
D002726	Chlorogenic Acid	Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein]	25043994
D002737	Chloroprene	Chloroprene results in increased expression of CYP2E1 mRNA	23125180
D002746	Chlorpromazine	Chlorpromazine results in decreased activity of CYP2E1 protein	15135088
D002746	Chlorpromazine	CYP2E1 protein results in decreased susceptibility to Chlorpromazine	26477383
D004390	Chlorpyrifos	Chlorpyrifos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D004390	Chlorpyrifos	Chlorpyrifos results in decreased activity of CYP2E1 protein	22634058
D002753	Chlorzoxazone	[5-bromotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	[5-chlorotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	[5-fluoro-alpha-methyltryptamine results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	[5-fluorotryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	"[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone"	26599973
D002753	Chlorzoxazone	[5-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	[7-methyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	Carbaryl inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	chlorfluazuron inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	[Chlormethiazole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	Chlorpyrifos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	[Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine	11502731
D002753	Chlorzoxazone	CYB5A protein promotes the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	15728263
D002753	Chlorzoxazone	CYP2E1 protein affects the hydroxylation of Chlorzoxazone	7747284
D002753	Chlorzoxazone	CYP2E1 protein affects the metabolism of Chlorzoxazone	12818727\|1458638
D002753	Chlorzoxazone	CYP2E1 protein results in increased hydroxylation of Chlorzoxazone	12433797\|1269049
D002753	Chlorzoxazone	CYP2E1 protein results in increased metabolism of Chlorzoxazone	12401345\|1246424
D002753	Chlorzoxazone	[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone	23669205
D002753	Chlorzoxazone	CYP2E1 protein results in increased oxidation of Chlorzoxazone	10207612\|2196441
D002753	Chlorzoxazone	cypermethrin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]	23669205
D002753	Chlorzoxazone	Fenitrothion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	fenvalerate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	[indopan analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	[indopan results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	isoproturon inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	[Methoxydimethyltryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	"[N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone"	26599973
D002753	Chlorzoxazone	"[N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone"	26599973
D002753	Chlorzoxazone	perfluorooctane sulfonic acid inhibits the reaction [CYP2E1 protein results in increased oxidation of Chlorzoxazone]	21964418
D002753	Chlorzoxazone	phenthoate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	profenofos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D002753	Chlorzoxazone	[Tryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D002753	Chlorzoxazone	CYP2E1 protein results in increased hydroxylation of Chlorzoxazone	10463382
D002753	Chlorzoxazone	CYP2E1 protein results in increased metabolism of Chlorzoxazone	25956474
D002753	Chlorzoxazone	resveratrol inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]	25956474
D002753	Chlorzoxazone	CYP2E1 protein results in increased hydroxylation of Chlorzoxazone	21600194
D002753	Chlorzoxazone	Pyrazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D002753	Chlorzoxazone	CYP2E1 protein affects the metabolism of Chlorzoxazone	15231049\|1587949
D002753	Chlorzoxazone	CYP2E1 protein results in increased hydroxylation of Chlorzoxazone	11911841\|1520538
D002753	Chlorzoxazone	CYP2E1 protein results in increased metabolism of Chlorzoxazone	28438436
D002753	Chlorzoxazone	[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone	28438436
D002753	Chlorzoxazone	Imidazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D002753	Chlorzoxazone	Isoquinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D002753	Chlorzoxazone	Pyridines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D002753	Chlorzoxazone	Quinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D002784	Cholesterol	Cholesterol results in decreased activity of CYP2E1 protein	18420780
D002793	Cholic Acids	[Methyltestosterone co-treated with Cholic Acids] affects the expression of CYP2E1 mRNA	27344345
D002794	Choline	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2E1 mRNA	22872676
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CYP2E1 protein	18952117
D002794	Choline	RXRA gene mutant form inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CYP2E1 protein]	18952117
D002794	Choline	Choline deficiency promotes the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	18798224
D002794	Choline	Choline deficiency promotes the reaction [Phenobarbital results in increased expression of CYP2E1 protein]	18798224
C031180	chrysene	chrysene results in increased expression of CYP2E1 mRNA	26377693
D002922	Ciguatoxins	Ciguatoxins affects the expression of CYP2E1 mRNA	18353800
D002927	Cimetidine	Cimetidine results in decreased expression of CYP2E1 protein	22733800
D002927	Cimetidine	[Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein	22733800
C029010	cinnamic acid	cinnamic acid analog results in decreased activity of CYP2E1 protein	15072549
C019304	ciprofibrate	[Acetone co-treated with ciprofibrate] results in increased expression of CYP2E1 protein	7587954
C019304	ciprofibrate	ciprofibrate results in increased expression of CYP2E1 mRNA	7587954
C019304	ciprofibrate	pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2E1 protein]	7587954
C019304	ciprofibrate	[Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein	7587954
D002994	Clofibrate	Clofibrate results in increased expression of CYP2E1 protein	19952500
D002994	Clofibrate	Clofibrate affects the expression of CYP2E1 mRNA	16081524
D002994	Clofibrate	[Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA	17585979
D002994	Clofibrate	PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CYP2E1 mRNA]	17585979
D002994	Clofibrate	Clofibrate results in increased expression of CYP2E1 mRNA	10476907
D002994	Clofibrate	Clofibrate results in increased expression of CYP2E1 protein	10476907
D009249	NADP	[vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	11181492
D009249	NADP	[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein	24713513
D003300	Copper	[CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol	15576237
D003300	Copper	Copper results in decreased expression of CYP2E1 mRNA	18522721
D003300	Copper	Copper results in decreased expression of CYP2E1 mRNA	22465980
D003367	Cotinine	Cotinine results in decreased activity of CYP2E1 protein	25221795
C030123	coumarin	coumarin affects the localization of CYP2E1 protein	28803882
D003407	Creosote	Creosote results in increased expression of CYP2E1 mRNA	19389177
C029036	crocin	crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]	25899501
C029036	crocin	crocin results in decreased activity of CYP2E1 protein	25899501
C007164	cumene hydroperoxide	cumene hydroperoxide inhibits the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form]	15379534
C007164	cumene hydroperoxide	cumene hydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein]	15379534
D003474	Curcumin	Curcumin inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein]	24508477
D003474	Curcumin	Curcumin affects the expression of CYP2E1 protein	16805852
D003474	Curcumin	Curcumin results in increased expression of CYP2E1 mRNA	18539377
D003486	Cyanides	[CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides	15893539
C057862	cyanoginosin LR	allyl sulfide inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]	21684301
C057862	cyanoginosin LR	Chlormethiazole inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]	21684301
C057862	cyanoginosin LR	cyanoginosin LR results in increased expression of CYP2E1 mRNA	21684301
C057862	cyanoginosin LR	cyanoginosin LR results in increased expression of CYP2E1 protein	21684301
C057862	cyanoginosin LR	sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]	21684301
C057862	cyanoginosin LR	sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein]	21684301
D003511	Cyclohexanols	[Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein	17393424
D003513	Cycloheximide	(4-amidinophenyl)methanesulfonyl fluoride inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	"6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]"	9143349
D003513	Cycloheximide	acetonitrile inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Carbon Tetrachloride promotes the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136\|9143349
D003513	Cycloheximide	Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	9143349
D003513	Cycloheximide	Cycloheximide promotes the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]	8531136
D003513	Cycloheximide	Cycloheximide results in increased degradation of CYP2E1 protein	9143349
D003513	Cycloheximide	Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D003513	Cycloheximide	Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D003513	Cycloheximide	Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]	1968335
D003513	Cycloheximide	Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein]	1968335
D003520	Cyclophosphamide	CYP2E1 results in increased metabolism of Cyclophosphamide	20566340
D016572	Cyclosporine	Cyclosporine results in decreased expression of CYP2E1 mRNA	20106945\|2383089
D016572	Cyclosporine	Cyclosporine results in decreased expression of CYP2E1 mRNA	23830897
C052570	cyfluthrin	cyfluthrin results in increased activity of CYP2E1 protein	23639246
C017160	cypermethrin	cypermethrin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
C017160	cypermethrin	cypermethrin results in decreased activity of CYP2E1 protein	22634058
C017160	cypermethrin	cypermethrin results in decreased activity of CYP2E1 protein	18420780
C017160	cypermethrin	[cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein	25926273
C017160	cypermethrin	cypermethrin results in increased activity of CYP2E1 protein	25926273
C017160	cypermethrin	cypermethrin results in increased expression of CYP2E1 mRNA	20815782\|2344709
C017160	cypermethrin	cypermethrin results in increased expression of CYP2E1 protein	23447098
C093628	cyproconazole	[cyproconazole co-treated with epoxiconazole] results in increased expression of CYP2E1 mRNA	29038839
C004742	daidzein	daidzein results in decreased activity of CYP2E1 protein	18420780
C017180	decamethrin	decamethrin results in increased activity of CYP2E1 protein	16494911
C017180	decamethrin	decamethrin results in increased expression of CYP2E1 mRNA	16494911\|1685967
C017180	decamethrin	decamethrin results in increased expression of CYP2E1 protein	16859670
C017180	decamethrin	Vitamin E inhibits the reaction [decamethrin results in increased expression of CYP2E1 mRNA]	25439240
C031071	decanoic acid	[CYP2E1 protein co-treated with POR protein] results in increased hydroxylation of decanoic acid	2292581
D003671	DEET	CYP2E1 protein results in increased metabolism of DEET	11854147
D003671	DEET	[fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA	27091632
D003676	Deferoxamine	Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D003687	Dehydroepiandrosterone	Dehydroepiandrosterone results in decreased expression of CYP2E1 mRNA	22713311
D003840	Deoxycholic Acid	Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein	10453939
D003840	Deoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein]	10453939
D003891	Desipramine	Desipramine results in decreased activity of CYP2E1 protein	15135088
D003907	Dexamethasone	Dexamethasone results in increased expression of CYP2E1 mRNA	21041162
D003907	Dexamethasone	"2-amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine inhibits the reaction [Dexamethasone results in increased expression of CYP2E1 mRNA]"	20501703
D003907	Dexamethasone	Dexamethasone results in decreased expression of CYP2E1 protein	11181506
D003907	Dexamethasone	Dexamethasone results in increased expression of CYP2E1 mRNA	14618091\|2050170
D003907	Dexamethasone	Dexamethasone results in increased expression of CYP2E1 protein	15965953\|2050170
D003907	Dexamethasone	Quercetin promotes the reaction [Dexamethasone results in increased expression of CYP2E1 mRNA]	20501703
D003907	Dexamethasone	Quercetin promotes the reaction [Dexamethasone results in increased expression of CYP2E1 protein]	20501703
D016264	Dextran Sulfate	Dextran Sulfate results in decreased activity of CYP2E1 protein	28438436
D016264	Dextran Sulfate	[Dextran Sulfate results in decreased activity of CYP2E1 protein] which results in decreased chemical synthesis of 6-hydroxychlorzoxazone	28438436
C028009	diallyl disulfide	diallyl disulfide inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	19325051
C028009	diallyl disulfide	diallyl disulfide results in decreased activity of CYP2E1 protein	18339364
C028009	diallyl disulfide	diallyl disulfide results in decreased expression of CYP2E1 protein	10774820
C028009	diallyl disulfide	[diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene	10774820
C028009	diallyl disulfide	diallyl disulfide results in decreased expression of CYP2E1 protein	16000231\|2429338
C068327	diallyl sulfone	diallyl sulfone inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	11181492
C068327	diallyl sulfone	diallyl sulfone inhibits the reaction [CYP2E1 protein results in increased metabolism of vinylidene chloride]	10215634
C068327	diallyl sulfone	diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate]	17341656
C068327	diallyl sulfone	diallyl sulfone results in decreased activity of CYP2E1 protein	17341656
C068327	diallyl sulfone	[diallyl sulfone results in decreased activity of CYP2E1 protein] which affects the susceptibility to vinyl carbamate	20205516
C068327	diallyl sulfone	diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate]	17296623
C068327	diallyl sulfone	CYP2E1 affects the oxidation of diallyl sulfone	17341656
C042577	diallyl trisulfide	diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]	28115069
C042577	diallyl trisulfide	diallyl trisulfide results in decreased expression of CYP2E1 protein	28115069
D015946	Ethylene Dibromide	CYP2E1 protein results in increased metabolism of Ethylene Dibromide	10841534\|1835091
D015946	Ethylene Dibromide	CYP2E1 protein results in increased oxidation of Ethylene Dibromide	1664256
C012279	dibutylnitrosamine	[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to dibutylnitrosamine	11733072
C012279	dibutylnitrosamine	[CYP2E1 protein co-treated with POR protein] results in increased susceptibility to dibutylnitrosamine	11035158
C012279	dibutylnitrosamine	CYP2E1 protein results in increased metabolism of dibutylnitrosamine	8625499
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased activity of CYP2E1 protein	27432241
D003994	Bucladesine	Bucladesine promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
D002945	Cisplatin	Chlorogenic Acid inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein]	25043994
D002945	Cisplatin	Cisplatin results in increased expression of and results in increased activity of CYP2E1 protein	21616140
D002945	Cisplatin	Cisplatin results in increased expression of CYP2E1 protein	23770416\|2504399
D002945	Cisplatin	Luteolin inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein]	23770416
D002945	Cisplatin	Cisplatin results in decreased activity of CYP2E1 protein	24882083
D002945	Cisplatin	Cisplatin results in increased expression of CYP2E1 mRNA	22023808
D002945	Cisplatin	CYP2E1 protein results in increased susceptibility to Cisplatin	20809784
D002945	Cisplatin	turmeric extract affects the reaction [Cisplatin results in decreased activity of CYP2E1 protein]	24882083
D004008	Diclofenac	Diclofenac metabolite results in decreased activity of CYP2E1 protein	28960974
D004010	Dicofol	Dicofol results in increased expression of CYP2E1 protein	19595748
D001728	Dicumarol	Dicumarol promotes the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D004041	Dietary Fats	7-hydroxycoumarin inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein]	24661945
D004041	Dietary Fats	CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IFNG mRNA]	24211274
D004041	Dietary Fats	CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL1B mRNA]	24211274
D004041	Dietary Fats	CYP2E1 protein affects the reaction [[bromodichloromethane co-treated with Dietary Fats] results in increased expression of IL2 mRNA]	24211274
D004041	Dietary Fats	CYP2E1 protein affects the susceptibility to [bromodichloromethane co-treated with Dietary Fats]	24211274
D004041	Dietary Fats	Dietary Fats affects the expression of CYP2E1 protein	23358370
D004041	Dietary Fats	[Dietary Fats co-treated with bromodichloromethane] results in increased expression of CYP2E1 protein	23438451
D004041	Dietary Fats	Dietary Fats results in decreased expression of CYP2E1 mRNA	18042831\|2395440
D004041	Dietary Fats	Dietary Fats results in increased activity of CYP2E1 protein	24661945
D004041	Dietary Fats	Dietary Fats results in increased expression of CYP2E1 protein	23358370
D004041	Dietary Fats	Hymecromone inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein]	24661945
D004041	Dietary Fats	[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein	19551842
D004041	Dietary Fats	[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein	24815820
D004041	Dietary Fats	Dietary Fats results in increased expression of CYP2E1 protein	17967931
D004041	Dietary Fats	Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein]	19551842
D004042	Dietary Fats, Unsaturated	"Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of CYP2E1 mRNA]"	23626681
D004042	Dietary Fats, Unsaturated	"Dietary Fats, Unsaturated results in increased expression of CYP2E1 mRNA"	23626681
D004052	Diethylnitrosamine	CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of Diethylnitrosamine]	15728263
D004052	Diethylnitrosamine	CYP2E1 protein affects the metabolism of and results in increased activity of Diethylnitrosamine	11774366
D004052	Diethylnitrosamine	CYP2E1 protein affects the metabolism of Diethylnitrosamine	2655891
D004052	Diethylnitrosamine	[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Diethylnitrosamine	11733072
D004052	Diethylnitrosamine	[CYP2E1 protein co-treated with POR protein] results in increased susceptibility to Diethylnitrosamine	11035158
D004052	Diethylnitrosamine	CYP2E1 protein results in increased activity of Diethylnitrosamine	15728263
D004052	Diethylnitrosamine	CYP2E1 protein results in increased susceptibility to Diethylnitrosamine	14669323
D004052	Diethylnitrosamine	CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of BAX mRNA]	18056438
D004052	Diethylnitrosamine	CYP2E1 protein promotes the reaction [Diethylnitrosamine results in increased expression of CASP3 mRNA]	18056438
D004052	Diethylnitrosamine	CYP2E1 protein results in increased susceptibility to Diethylnitrosamine	18056438
D004052	Diethylnitrosamine	[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA	16158176
D004052	Diethylnitrosamine	allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP2E1 protein]	23494807
D004052	Diethylnitrosamine	allyl sulfide inhibits the reaction [Diethylnitrosamine results in decreased expression of CYP2E1 mRNA]	23494807
D004052	Diethylnitrosamine	[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein	19551842
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA	14656948
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein	17393424
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein	16246485
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP2E1 mRNA	20360939
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Cyclohexanols] results in increased expression of CYP2E1 protein	17393424
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA	18544905
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2E1 mRNA	28943392
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of and results in decreased activity of CYP2E1 protein	23494807
D004052	Diethylnitrosamine	Diethylnitrosamine results in decreased expression of CYP2E1 mRNA	19638242\|2036093
D004052	Diethylnitrosamine	Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein]	19551842
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CYP2E1 mRNA	21041162
C035318	diethylthiourea	diethylthiourea results in increased expression of CYP2E1 protein	10190572
C012906	dihydrocapsaicin	dihydrocapsaicin results in increased expression of CYP2E1	22375877
C472036	dihydromyricetin	dihydromyricetin inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	28419832
C039353	dihydroxyethyldithiocarbamate	dihydroxyethyldithiocarbamate inhibits the reaction [CYP2E1 protein results in increased metabolism of chlorobenzene]	9817075
C039353	dihydroxyethyldithiocarbamate	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]	9817075
C039353	dihydroxyethyldithiocarbamate	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]	9817075
C039353	dihydroxyethyldithiocarbamate	dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of chlorobenzene]	9817075
D004114	Dimethadione	CYP2E1 protein results in decreased methylation of Dimethadione	8865369
D015127	9,10-Dimethyl-1,2-benzanthracene	"CYP2E1 protein affects the susceptibility to 9,10-Dimethyl-1,2-benzanthracene"	18622027
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP2E1 mRNA"	24576726
D004126	Dimethylformamide	CYP2E1 protein polymorphism affects the metabolism of Dimethylformamide	11305777
D004126	Dimethylformamide	CYP2E1 protein results in increased metabolism of Dimethylformamide	9817075
D004126	Dimethylformamide	CYP2E1 protein results in increased oxidation of Dimethylformamide	10207612
D004126	Dimethylformamide	Dimethylformamide results in increased expression of CYP2E1 protein	10547960
D004126	Dimethylformamide	CYP2E1 protein affects the metabolism of Dimethylformamide	15772367
D019813	1,2-Dimethylhydrazine	"1,2-Dimethylhydrazine results in increased activity of CYP2E1 protein"	19497424\|2910877
D019813	1,2-Dimethylhydrazine	"asiatic acid inhibits the reaction [1,2-Dimethylhydrazine results in increased activity of CYP2E1 protein]"	29108773
D019813	1,2-Dimethylhydrazine	"hesperetin inhibits the reaction [1,2-Dimethylhydrazine results in increased activity of CYP2E1 protein]"	19497424
C073972	dimethyl mercury	[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]	21424224
C073972	dimethyl mercury	dimethyl mercury results in decreased expression of CYP2E1 protein	21424224
D004128	Dimethylnitrosamine	CYP2E1 protein affects the metabolism of and results in increased activity of Dimethylnitrosamine	11600130
D004128	Dimethylnitrosamine	CYP2E1 protein affects the metabolism of Dimethylnitrosamine	16235733\|2655891
D004128	Dimethylnitrosamine	[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Dimethylnitrosamine	11733072
D004128	Dimethylnitrosamine	CYP2E1 protein results in decreased methylation of Dimethylnitrosamine	11181492
D004128	Dimethylnitrosamine	CYP2E1 protein results in increased metabolism of and results in increased activity of Dimethylnitrosamine	11960914
D004128	Dimethylnitrosamine	CYP2E1 protein results in increased metabolism of Dimethylnitrosamine	12464242\|1524281
D004128	Dimethylnitrosamine	diallyl sulfone inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	11181492
D004128	Dimethylnitrosamine	Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D004128	Dimethylnitrosamine	Dimethylnitrosamine inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]	8531136
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in decreased activity of CYP2E1 protein	24561005
D004128	Dimethylnitrosamine	Ethanol affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	16235733
D004128	Dimethylnitrosamine	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of Dimethylnitrosamine]	8074729
D004128	Dimethylnitrosamine	Lipopolysaccharides affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	16235733
D004128	Dimethylnitrosamine	[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine	27913846
D004128	Dimethylnitrosamine	[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to Dimethylnitrosamine] which results in increased mutagenesis of HPRT1 gene	27913846
D004128	Dimethylnitrosamine	[vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	11181492
D004128	Dimethylnitrosamine	Dimethylnitrosamine results in decreased expression of CYP2E1 mRNA	11356909
D004128	Dimethylnitrosamine	Alloxan affects the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	17034923
D004128	Dimethylnitrosamine	CYP2E1 protein affects the metabolism of Dimethylnitrosamine	15815077
D004128	Dimethylnitrosamine	[CYP2E1 protein co-treated with POR protein] results in decreased methylation of Dimethylnitrosamine	2292581
D004128	Dimethylnitrosamine	CYP2E1 protein results in decreased methylation of Dimethylnitrosamine	17034923
D004128	Dimethylnitrosamine	Dimethylnitrosamine binds to CYP2E1 protein	15815077
D004128	Dimethylnitrosamine	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	8117321
D004128	Dimethylnitrosamine	CYP2E1 protein results in decreased methylation of Dimethylnitrosamine	3113478\|8194125
D004128	Dimethylnitrosamine	CYP2E1 protein results in increased metabolism of Dimethylnitrosamine	15763544
D004128	Dimethylnitrosamine	S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	15763544
D004128	Dimethylnitrosamine	CYP2E1 protein results in increased metabolism of and results in increased activity of Dimethylnitrosamine	16142352
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide affects the expression of CYP2E1 mRNA	12843640
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]	12147272
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide results in increased expression of CYP2E1 protein	8074729
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide results in increased activity of CYP2E1 protein	17177172
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide binds to and results in increased expression of CYP2E1 protein	3337723
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of 7-methoxy-4-trifluoromethylcoumarin]	19858067
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide results in increased expression of CYP2E1 protein	3113478
C106479	di-n-propylphthalate	di-n-propylphthalate results in decreased activity of CYP2E1 protein	27432241
C019357	dioscin	dioscin inhibits the reaction [Acetaminophen results in increased expression of and results in increased activity of CYP2E1 protein]	22939915
C019357	dioscin	dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24146112
C019357	dioscin	dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24146112
C039602	diosmetin	diosmetin results in decreased activity of CYP2E1 protein	28867436
D004145	Diosmin	Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein]	23665045
D004148	Dioxolanes	Dioxolanes results in decreased activity of CYP2E1 protein	16331285
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]	26880746
C007517	diphenyleneiodonium	diphenyleneiodonium results in decreased activity of CYP2E1 protein	26880746
C087894	dipropyl sulfide	dipropyl sulfide results in decreased activity of CYP2E1 protein	18339364
D004221	Disulfiram	Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]	23669205
D004221	Disulfiram	Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane]	10805064
D004221	Disulfiram	Disulfiram results in decreased activity of CYP2E1 protein	1664256\|8637342
D004221	Disulfiram	[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene	20470765
D004221	Disulfiram	[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene	20470765
D004221	Disulfiram	Disulfiram binds to and results in decreased activity of CYP2E1 protein	18754103
D004221	Disulfiram	Disulfiram results in decreased activity of CYP2E1 protein	9393675
D004221	Disulfiram	Disulfiram results in decreased expression of CYP2E1 mRNA	9393675
D004221	Disulfiram	Disulfiram results in decreased expression of CYP2E1 protein	9393675
D004221	Disulfiram	Disulfiram inhibits the reaction [4-xylene results in increased activity of CYP2E1 protein]	12781212
D004221	Disulfiram	Disulfiram inhibits the reaction [Toluene results in increased activity of CYP2E1 protein]	12781212
D004221	Disulfiram	Disulfiram results in decreased activity of CYP2E1	12803597
D004221	Disulfiram	Disulfiram results in decreased activity of CYP2E1 protein	19616568\|2047076
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]	8592870
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of lamotrigine]	19961160
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 2-xylene]	8558417
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 3-xylene]	8558417
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-xylene]	8558417
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]	10215755
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene]	8558417
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]	12086689
D004050	Ditiocarb	Ditiocarb results in decreased activity of CYP2E1 protein	15306208\|1664256
D004050	Ditiocarb	[Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene	12746132
D004050	Ditiocarb	[Ditiocarb results in decreased activity of CYP2E1 protein] which results in decreased oxidation of Benzene	8560479
D004050	Ditiocarb	Ditiocarb inhibits the reaction [[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Benzene]	9010585
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	9618253
D004050	Ditiocarb	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
D004050	Ditiocarb	Ditiocarb inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]	9618253
D004050	Ditiocarb	Ditiocarb results in decreased activity of CYP2E1 protein	1356728
D004050	Ditiocarb	Ditiocarb results in decreased activity of CYP2E1	10910959
D004050	Ditiocarb	Ditiocarb results in decreased activity of CYP2E1 protein	12086689\|1961656
D004281	Docosahexaenoic Acids	Chlormethiazole inhibits the reaction [Docosahexaenoic Acids results in increased expression of CYP2E1 protein]	16963249
D004281	Docosahexaenoic Acids	CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids	16963249
D004281	Docosahexaenoic Acids	[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which affects the localization of FASLG protein	16963249
D004281	Docosahexaenoic Acids	[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased activity of CASP3 protein	16963249
D004281	Docosahexaenoic Acids	[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased activity of CASP7 protein	16963249
D004281	Docosahexaenoic Acids	[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased expression of BAD protein	16963249
D004281	Docosahexaenoic Acids	[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased phosphorylation of MAP2K4 protein	16963249
D004281	Docosahexaenoic Acids	Docosahexaenoic Acids results in decreased activity of CYP2E1 protein	16978661
D004281	Docosahexaenoic Acids	Docosahexaenoic Acids results in increased expression of CYP2E1 protein	16963249
D004281	Docosahexaenoic Acids	Quercetin inhibits the reaction [[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased phosphorylation of MAP2K4 protein]	16963249
D004298	Dopamine	Dopamine results in decreased activity of CYP2E1 protein	18420780
D004317	Doxorubicin	Doxorubicin results in increased expression of CYP2E1 mRNA	26873546
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]"	24582681
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in decreased expression of CYP2E1 mRNA"	15706880\|2659009
C042986	ebselen	ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	11903743
D004492	Edetic Acid	Edetic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D004533	Egtazic Acid	Egtazic Acid inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D015118	Eicosapentaenoic Acid	Eicosapentaenoic Acid results in decreased activity of CYP2E1 protein	16978661
C034192	ellipticine	CYP2E1 protein results in increased metabolism of ellipticine	22917556
C070609	EMD 53998	EMD 53998 analog results in increased expression of CYP2E1 mRNA	24977338
D004726	Endosulfan	[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2E1 mRNA	26159488
D004726	Endosulfan	Endosulfan promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA]	28673560
D004726	Endosulfan	Endosulfan results in decreased expression of CYP2E1 mRNA	26159488\|2867356
D004726	Endosulfan	Endosulfan results in decreased expression of CYP2E1 protein	28673560
D004726	Endosulfan	Tetrachlorodibenzodioxin promotes the reaction [Endosulfan results in decreased expression of CYP2E1 mRNA]	28673560
C105196	enfuvirtide	enfuvirtide affects the activity of CYP2E1 protein	15656696
D004785	Environmental Pollutants	CYP2E1 polymorphism affects the susceptibility to Environmental Pollutants	19686770
C045651	epigallocatechin gallate	epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of CYP2E1 protein]	24508477
C045651	epigallocatechin gallate	epigallocatechin gallate results in increased expression of and results in increased activity of CYP2E1 protein	14600287
C045651	epigallocatechin gallate	epigallocatechin gallate binds to CYP2E1 protein	23010222
C109476	epoxiconazole	[cyproconazole co-treated with epoxiconazole] results in increased expression of CYP2E1 mRNA	29038839
C091891	epsilon-viniferin	epsilon-viniferin results in decreased activity of CYP2E1 protein	12818727
C007366	erythritol anhydride	CYP2E1 gene polymorphism affects the susceptibility to erythritol anhydride	15036125
C007366	erythritol anhydride	CYP2E1 gene polymorphism results in increased susceptibility to erythritol anhydride	17078101
C007633	estragole	CYP2E1 protein results in increased hydroxylation of estragole	19920071
D004967	Estrogens	Estrogens results in decreased expression of CYP2E1 protein	2785912
D004977	Ethambutol	Ethambutol results in decreased activity of CYP2E1 protein	24910189
D004977	Ethambutol	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein	27919644
D004977	Ethambutol	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA	27919644
D004977	Ethambutol	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D004977	Ethambutol	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D004977	Ethambutol	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D004977	Ethambutol	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D000431	Ethanol	[Ascorbic Acid co-treated with Ethanol] results in decreased expression of CYP2E1 mRNA	22149461
D000431	Ethanol	Ethanol results in increased activity of CYP2E1 protein	12451447
D000431	Ethanol	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	28385499
D000431	Ethanol	4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	28385499
D000431	Ethanol	allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	22138249
D000431	Ethanol	[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein	17034788
D000431	Ethanol	[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein	17034788
D000431	Ethanol	[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein	17034788
D000431	Ethanol	Betaine promotes the reaction [Ethanol results in increased expression of CYP2E1]	21352821
D000431	Ethanol	Catechin inhibits the reaction [Ethanol results in increased expression of CYP2E1]	21352821
D000431	Ethanol	CYP2E1 gene polymorphism affects the susceptibility to Ethanol	20171022
D000431	Ethanol	CYP2E1 protein affects the reaction [Ethanol results in decreased expression of DBN1 mRNA]	28385499
D000431	Ethanol	CYP2E1 protein affects the reaction [Ethanol results in decreased expression of PPARA mRNA]	28385499
D000431	Ethanol	CYP2E1 protein affects the reaction [Ethanol results in decreased expression of SYP mRNA]	28385499
D000431	Ethanol	CYP2E1 protein promotes the reaction [Ethanol results in increased expression of GCLC mRNA]	19133322
D000431	Ethanol	CYP2E1 protein results in increased metabolism of Ethanol	10573527\|1082610
D000431	Ethanol	[CYP2E1 protein results in increased metabolism of Ethanol] promotes the reaction [Ethanol results in increased expression of CYP2A6]	22530035
D000431	Ethanol	[CYP2E1 protein results in increased metabolism of Ethanol] which results in decreased abundance of Glutathione	10573527
D000431	Ethanol	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Acetaldehyde	18845238
D000431	Ethanol	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Nitric Oxide	18845238
D000431	Ethanol	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species	18845238
D000431	Ethanol	CYP2E1 protein results in increased susceptibility to Ethanol	8798623
D000431	Ethanol	diallyl disulfide inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	19325051
D000431	Ethanol	Ethanol affects the activity of CYP2E1 protein	22530035
D000431	Ethanol	[Ethanol affects the activity of CYP2E1 protein] which affects the localization of NFE2L2 protein	22530035
D000431	Ethanol	[[Ethanol affects the activity of CYP2E1 protein] which affects the localization of NFE2L2 protein] which results in increased expression of CYP2A6	22530035
D000431	Ethanol	Ethanol affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	16235733
D000431	Ethanol	Ethanol affects the reaction [CYP2E1 protein results in increased susceptibility to Acetaminophen]	11212141
D000431	Ethanol	[Ethanol co-treated with CYP2E1 protein] results in increased abundance of Reactive Oxygen Species	22222162
D000431	Ethanol	[Ethanol co-treated with CYP2E1 protein] results in increased phosphorylation of EGFR protein	22222162
D000431	Ethanol	Ethanol inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D000431	Ethanol	Ethanol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8074729\|8531136
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of aniline]	8074729
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of Dimethylnitrosamine]	8074729
D000431	Ethanol	Ethanol results in increased activity of CYP2E1 protein	11212141\|8074729
D000431	Ethanol	Ethanol results in increased expression of and results in increased activity of CYP2E1 protein	15802389\|1884523
D000431	Ethanol	Ethanol results in increased expression of CYP2E1	21352821
D000431	Ethanol	Ethanol results in increased expression of CYP2E1 mRNA	23300006\|2466350
D000431	Ethanol	Ethanol results in increased expression of CYP2E1 protein	17590308\|2213824
D000431	Ethanol	fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species]	18845238
D000431	Ethanol	Hemin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	19325051
D000431	Ethanol	Monocrotophos promotes the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24663500
D000431	Ethanol	Monocrotophos promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	24663500
D000431	Ethanol	Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	19325051
D000431	Ethanol	Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol]	8798623
D000431	Ethanol	tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	19325051
D000431	Ethanol	U 0126 inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	28385499
D000431	Ethanol	U 0126 inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	28385499
D000431	Ethanol	zinc protoporphyrin inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]]	19325051
D000431	Ethanol	zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]]	19325051
D000431	Ethanol	allyl sulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	22138249
D000431	Ethanol	[AQP4 protein affects the susceptibility to Ethanol] which affects the expression of CYP2E1 mRNA	20615459
D000431	Ethanol	Berberine inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	25455889
D000431	Ethanol	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
D000431	Ethanol	Chlormethiazole inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	22552773
D000431	Ethanol	Chlormethiazole inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24892905
D000431	Ethanol	CYP2E1 protein affects the reaction [Ethanol results in increased expression of and results in increased activity of CYP2A5 protein]	22552773
D000431	Ethanol	CYP2E1 protein affects the reaction [Ethanol results in increased expression of CYP2A5]	28131861
D000431	Ethanol	CYP2E1 protein results in increased oxidation of Ethanol	22552773
D000431	Ethanol	CYP2E1 protein results in increased susceptibility to Ethanol	28131861
D000431	Ethanol	dihydromyricetin inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	28419832
D000431	Ethanol	dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24146112
D000431	Ethanol	Ethanol promotes the reaction [Fructose results in increased expression of CYP2E1 protein]	26858005
D000431	Ethanol	Ethanol results in decreased expression of CYP2E1 mRNA	28119953
D000431	Ethanol	Ethanol results in increased activity of CYP2E1 protein	10667633\|1592015
D000431	Ethanol	Ethanol results in increased expression of and results in increased activity of CYP2E1 protein	22552773\|2414611
D000431	Ethanol	Ethanol results in increased expression of CYP2E1	16317704
D000431	Ethanol	Ethanol results in increased expression of CYP2E1 protein	11515535\|1592015
D000431	Ethanol	Plant Extracts inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	28797650
D000431	Ethanol	Silymarin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	28797650
D000431	Ethanol	SOD1 protein affects the reaction [Ethanol results in increased expression of CYP2E1 protein]	19951287
D000431	Ethanol	[Urethane co-treated with Ethanol] results in increased activity of CYP2E1 protein	15582191
D000431	Ethanol	[Zinc deficiency co-treated with Ethanol] results in increased expression of CYP2E1 protein	24155903
D000431	Ethanol	Zinc Sulfate inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	15920153
D000431	Ethanol	Zinc Sulfate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	15920153
D000431	Ethanol	allyl sulfide inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	20116195
D000431	Ethanol	Carnitine promotes the reaction [Ethanol results in increased expression of CYP2E1 protein]	8130774
D000431	Ethanol	CYP2E1 protein results in increased metabolism of Ethanol	11147839\|1576354
D000431	Ethanol	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde	7562599
D000431	Ethanol	CYP2E1 protein results in increased susceptibility to Ethanol	21130154
D000431	Ethanol	dioscin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24146112
D000431	Ethanol	Ethanol affects the activity of CYP2E1 protein	17533807
D000431	Ethanol	Ethanol binds to and results in increased expression of CYP2E1 protein	3337723
D000431	Ethanol	[Ethanol co-treated with nitrosobenzylmethylamine] results in increased expression of CYP2E1 protein	16704527
D000431	Ethanol	Ethanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D000431	Ethanol	Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA]	26854922
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	23274713
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene]	1994898
D000431	Ethanol	Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D000431	Ethanol	Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D000431	Ethanol	Ethanol results in increased activity of and results in increased expression of CYP2E1 protein	23274713
D000431	Ethanol	Ethanol results in increased activity of CYP2E1 protein	15998439\|2011619
D000431	Ethanol	[Ethanol results in increased activity of CYP2E1 protein] which results in increased metabolism of vinyl fluoride	9073601
D000431	Ethanol	Ethanol results in increased expression of and results in increased activity of CYP2E1 protein	15946133\|2199951
D000431	Ethanol	Ethanol results in increased expression of CYP2E1 mRNA	21999510\|2296044
D000431	Ethanol	Ethanol results in increased expression of CYP2E1 protein	19609968\|2381993
D000431	Ethanol	Genistein inhibits the reaction [Ethanol promotes the reaction [CYP2E1 protein results in increased hydroxylation of aniline]]	23274713
D000431	Ethanol	Genistein inhibits the reaction [Ethanol results in increased activity of and results in increased expression of CYP2E1 protein]	23274713
D000431	Ethanol	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA]	26747958
D000431	Ethanol	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein]	26747958
D000431	Ethanol	Oleanolic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	25111957
D000431	Ethanol	[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	26854922
D000431	Ethanol	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA	26747958
D000431	Ethanol	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 protein	26747958
D000431	Ethanol	[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA	26747958
D000431	Ethanol	[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein	26747958
D000431	Ethanol	phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde]	7562599
D000431	Ethanol	phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	7562599
D000431	Ethanol	phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	7562599
D000431	Ethanol	Plant Extracts inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	22525864
D000431	Ethanol	S-Adenosylmethionine inhibits the reaction [CYP2E1 protein results in increased metabolism of Ethanol]	15763544
D000431	Ethanol	salvianolic acid B inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	27989594
D000431	Ethanol	zingerone inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	28442378
D000431	Ethanol	CYP2E1 protein results in increased metabolism of Ethanol	16470306\|1673797
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Tretinoin]	16054987
D000431	Ethanol	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Vitamin A]	16054987
D000431	Ethanol	Ethanol results in decreased activity of CYP2E1 protein	7710944
D000431	Ethanol	Ethanol results in increased expression of CYP2E1 protein	16054987
D005013	Ethosuximide	CYP2E1 protein affects the metabolism of Ethosuximide	1438522
C004912	ethylbenzene	ethylbenzene results in increased expression of and results in increased activity of CYP2E1 protein	11884239
C004912	ethylbenzene	ethylbenzene results in increased expression of CYP2E1 mRNA	11884239
C004912	ethylbenzene	ethylbenzene results in increased expression of CYP2E1 protein	1417939\|8517779
C004912	ethylbenzene	GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein]	11884239
C036216	ethylene	CYP2E1 protein results in increased metabolism of ethylene	21785163
C036216	ethylene	[CYP2E1 protein results in increased metabolism of ethylene] which results in increased abundance of Ethylene Oxide	21785163
C036216	ethylene	ethylene results in decreased activity of CYP2E1 protein	15141094
C025475	ethylene bromohydrin	CYP2E1 protein results in increased metabolism of ethylene bromohydrin	8861782
C024565	ethylene dichloride	CYP2E1 protein results in increased oxidation of ethylene dichloride	1664256
C024565	ethylene dichloride	allyl sulfide inhibits the reaction [ethylene dichloride results in increased expression of CYP2E1 protein]	27301210
C024565	ethylene dichloride	ethylene dichloride results in increased expression of CYP2E1 mRNA	28189721
C024565	ethylene dichloride	ethylene dichloride results in increased expression of CYP2E1 protein	27301210\|2818972
D005027	Ethylene Oxide	[CYP2E1 protein results in increased metabolism of ethylene] which results in increased abundance of Ethylene Oxide	21785163
D005020	Ethyl Methanesulfonate	Ethyl Methanesulfonate results in decreased expression of CYP2E1 mRNA	23649840
C012313	ethyl-p-hydroxybenzoate	ethyl-p-hydroxybenzoate results in decreased activity of CYP2E1 protein	27432241
C098546	ethyl tert-butyl ether	ethyl tert-butyl ether results in increased expression of CYP2E1 mRNA	24090815
C098546	ethyl tert-butyl ether	ethyl tert-butyl ether results in increased expression of CYP2E1 protein	24090815
D005054	Eugenol	[CYP2E1 protein co-treated with Copper] results in increased activity of Eugenol	15576237
D005054	Eugenol	Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein]	20036707
D015025	Zearalenone	Zearalenone results in increased expression of CYP2E1 mRNA	20607812
D005204	Farnesol	Farnesol results in increased activity of CYP2E1 protein	15840382
D005227	Fatty Acids	[Acetaminophen results in increased activity of CYP2E1 protein] inhibits the reaction [PPARA protein results in increased oxidation of Fatty Acids]	19256530
C047360	felbamate	felbamate results in decreased expression of CYP2E1 mRNA	17381134
C033789	fenarimol	[fenarimol co-treated with acephate] affects the expression of CYP2E1 protein	17686559
C033789	fenarimol	[fenarimol co-treated with vinclozolin] affects the expression of CYP2E1 protein	17686559
C033789	fenarimol	[fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein	17686559
D005273	Fenbendazole	Fenbendazole affects the expression of CYP2E1 mRNA	26366864
D005278	Fenitrothion	Fenitrothion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D005278	Fenitrothion	Fenitrothion results in decreased activity of CYP2E1 protein	22634058
D011345	Fenofibrate	Fenofibrate results in increased expression of CYP2E1 mRNA	19118567
C017690	fenvalerate	fenvalerate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
C017690	fenvalerate	fenvalerate results in decreased activity of CYP2E1 protein	22634058
C045858	ferric-adenosine triphosphate complex	ferric-adenosine triphosphate complex inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
C045858	ferric-adenosine triphosphate complex	ferric-adenosine triphosphate complex results in increased degradation of CYP2E1 protein	8531136
C025314	ferric citrate	Alcohols inhibits the reaction [ferric citrate results in increased expression of CYP2E1 mRNA]	24025710
C025314	ferric citrate	ferric citrate inhibits the reaction [Alcohols results in increased expression of CYP2E1 mRNA]	24025710
C025314	ferric citrate	ferric citrate results in increased expression of CYP2E1 mRNA	24025710
C020326	ferric nitrilotriacetate	allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]	12086689
C020326	ferric nitrilotriacetate	[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein	17034788
C020326	ferric nitrilotriacetate	[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein	17034788
C020326	ferric nitrilotriacetate	[[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein	17034788
C020326	ferric nitrilotriacetate	CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]	12086689\|2135282
C020326	ferric nitrilotriacetate	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]	12086689
C020326	ferric nitrilotriacetate	"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]"	12086689
D005363	Ficusin	Ficusin results in decreased expression of CYP2E1 protein	22173200
C082360	fipronil	[fipronil co-treated with DEET] results in decreased expression of CYP2E1 mRNA	27091632
C082360	fipronil	fipronil results in decreased expression of CYP2E1 mRNA	27091632
C082360	fipronil	fipronil results in increased expression of CYP2E1 mRNA	23962444
D005411	Flame Retardants	Flame Retardants results in increased expression of CYP2E1 mRNA	26808241
D005419	Flavonoids	Flavonoids inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	23279844
C014558	flunixin meglumine	flunixin meglumine affects the expression of CYP2E1 mRNA	26366864
C007738	fluoranthene	fluoranthene results in increased expression of CYP2E1 mRNA	16269432
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene analog results in increased expression of CYP2E1 protein	15916741
D015073	2-Acetylaminofluorene	[2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA	16158176
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of CYP2E1 protein	15916741\|2366504
D015073	2-Acetylaminofluorene	[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP2E1 mRNA	14656948
D015073	2-Acetylaminofluorene	[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of CYP2E1 protein	17393424
D015073	2-Acetylaminofluorene	Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased expression of CYP2E1 protein]	23665045
D005476	Fluphenazine	Fluphenazine results in decreased activity of CYP2E1 protein	15135088
D005492	Folic Acid	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2E1 mRNA	22872676
C010238	fomepizole	fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]	8592870
C010238	fomepizole	fomepizole inhibits the reaction [Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
C010238	fomepizole	fomepizole inhibits the reaction [Carbon Tetrachloride results in increased degradation of CYP2E1 protein]	8531136
C010238	fomepizole	fomepizole inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C010238	fomepizole	"fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of 2,6-xylidine metabolite]"	11409937
C010238	fomepizole	fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species]	18845238
C010238	fomepizole	fomepizole results in decreased activity of CYP2E1 protein	21336516\|2456100
C010238	fomepizole	[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride	9073601
C010238	fomepizole	fomepizole results in increased expression of CYP2E1 protein	8074729
C010238	fomepizole	[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride	9073601
C010238	fomepizole	fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
C010238	fomepizole	[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride	9073601
C010238	fomepizole	fomepizole results in increased activity of CYP2E1 protein	3782137
C010238	fomepizole	fomepizole results in increased expression of CYP2E1 protein	3113478\|3782137
C010238	fomepizole	fomepizole results in decreased activity of CYP2E1 protein	10828259\|1673797
D005503	Food Additives	Food Additives results in increased expression of CYP2E1 mRNA	18803703
D005579	Fossil Fuels	Fossil Fuels results in increased expression of CYP2E1 protein	14961354
D005632	Fructose	Ethanol promotes the reaction [Fructose results in increased expression of CYP2E1 protein]	26858005
D005632	Fructose	Fructose results in decreased expression of CYP2E1 protein	28257781
D005632	Fructose	Fructose results in increased expression of CYP2E1 protein	26858005
C069837	fullerene C60	fullerene C60 results in increased expression of CYP2E1 mRNA	19167457
C056933	fumonisin B1	fumonisin B1 results in decreased expression of CYP2E1 mRNA	16221962
C050131	furafylline	furafylline results in decreased activity of CYP2E1 protein	15879494
C039281	furan	1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]	21842885
C039281	furan	[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde	21842885
C039281	furan	[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde	21842885
C039281	furan	furan results in decreased expression of CYP2E1 mRNA	15120968
C039281	furan	furan results in decreased expression of CYP2E1 protein	20124500
C039281	furan	CYP2E1 protein results in increased metabolism of furan	22240984\|2418370
C039281	furan	[CYP2E1 protein results in increased metabolism of furan] which results in increased chemical synthesis of malealdehyde	22240984\|2418370
C040029	gabapentin	gabapentin results in decreased expression of CYP2E1 mRNA	17381134
C038958	gadolinium chloride	gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA]	18202523
C038958	gadolinium chloride	gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein]	18202523
D005742	Gasoline	Gasoline results in increased expression of CYP2E1 protein	14961354
D019833	Genistein	Genistein inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	23333575
D019833	Genistein	[Genistein co-treated with Methoxychlor] results in increased expression of CYP2E1 mRNA	21782745
D019833	Genistein	Genistein inhibits the reaction [Ethanol promotes the reaction [CYP2E1 protein results in increased hydroxylation of aniline]]	23274713
D019833	Genistein	Genistein inhibits the reaction [Ethanol results in increased activity of and results in increased expression of CYP2E1 protein]	23274713
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in decreased activity of CYP2E1 protein	15147983
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in increased expression of and results in increased activity of CYP2E1 protein	18421621
C111520	ginsan	ginsan promotes the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	19913046
C111520	ginsan	ginsan results in decreased expression of CYP2E1 protein	19913046
D005897	Glafenine	Glafenine results in decreased expression of CYP2E1 mRNA	24136188
D005978	Glutathione	[CYP2E1 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac	24246759
D005978	Glutathione	[CYP2E1 protein results in increased metabolism of Ethanol] which results in decreased abundance of Glutathione	10573527
D005978	Glutathione	Glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene]	16872732
D005978	Glutathione	Glutathione inhibits the reaction [Alcohols results in increased expression of CYP2E1 protein]	28803762
D005978	Glutathione	1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]	21842885
D005978	Glutathione	[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde	21842885
D005978	Glutathione	[Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]	8211999
D005990	Glycerol	Glycerol inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C071834	glycidamide	[CYP2E1 gene polymorphism co-treated with EPHX1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the abundance of glycidamide	19131562
C071834	glycidamide	[CYP2E1 gene polymorphism co-treated with EPHX1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of glycidamide	19131562
C071834	glycidamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of glycidamide	19131562
C071834	glycidamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the abundance of glycidamide	19131562
C071834	glycidamide	[CYP2E1 protein results in increased oxidation of Acrylamide] which results in increased abundance of glycidamide	27174446
C071834	glycidamide	[CYP2E1 protein results in increased metabolism of Acrylamide] which results in increased chemical synthesis of glycidamide	25980586
D006034	Glycyrrhetinic Acid	[brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein	21800547
C511402	Grape Seed Proanthocyanidins	[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CYP2E1 mRNA	24763279
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein	12587719
C511402	Grape Seed Proanthocyanidins	CYP2E1 protein results in increased metabolism of Grape Seed Proanthocyanidins	11330834
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein	11330834
C511402	Grape Seed Proanthocyanidins	CYP2E1 protein results in increased metabolism of Grape Seed Proanthocyanidins	11330834
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein	11330834
C511402	Grape Seed Proanthocyanidins	[Grape Seed Proanthocyanidins results in decreased activity of CYP2E1 protein] which results in decreased hydroxylation of aniline	11330834
D055768	Halogenated Diphenyl Ethers	Halogenated Diphenyl Ethers results in increased expression of CYP2E1 mRNA	26808241
D006221	Halothane	CYP2E1 protein affects the metabolism of Halothane	9103523
D006221	Halothane	CYP2E1 protein results in increased metabolism of Halothane	11684365\|1246424
D006221	Halothane	CYP2E1 protein results in increased oxidation of Halothane	10805064
D006221	Halothane	Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane]	10805064
D006221	Halothane	CYP2E1 protein results in increased susceptibility to Halothane	12803597
D006221	Halothane	CYP2E1 protein results in increased oxidation of Halothane	12803597
D006427	Hemin	Hemin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	19325051
D006427	Hemin	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA]	26747958
D006427	Hemin	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein]	26747958
D006427	Hemin	Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D006427	Hemin	Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
C481602	heptylparaben	heptylparaben results in decreased activity of CYP2E1 protein	27432241
C013015	hesperetin	"hesperetin inhibits the reaction [1,2-Dimethylhydrazine results in increased activity of CYP2E1 protein]"	19497424
D006581	Hexachlorobenzene	Hexachlorobenzene results in decreased expression of CYP2E1 mRNA	15159207
D006581	Hexachlorobenzene	Hexachlorobenzene results in increased expression of CYP2E1 protein	10696772
C000625836	HFPO4 compound	HFPO4 compound results in decreased expression of CYP2E1 mRNA	27553808
C029424	hydrazine	hydrazine results in increased activity of CYP2E1 protein	15132840
D006854	Hydrocortisone	Hydrocortisone results in increased expression of CYP2E1 mRNA	10476907
D006854	Hydrocortisone	Hydrocortisone results in increased expression of CYP2E1 protein	10476907
D006861	Hydrogen Peroxide	CYP2E1 protein results in increased abundance of Hydrogen Peroxide	25061110
D047348	Hydrolyzable Tannins	Hydrolyzable Tannins results in decreased activity of CYP2E1 protein	12749824
D047348	Hydrolyzable Tannins	Hydrolyzable Tannins results in decreased expression of CYP2E1 protein	12749824
C031927	hydroquinone	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroquinone	15051535
C031927	hydroquinone	[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone	8211999
C031927	hydroquinone	[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone	8211999
C031927	hydroquinone	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone]	8211999
C031927	hydroquinone	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]	8211999
C031927	hydroquinone	[Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]	8211999
C013038	hydroxyhydroquinone	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of hydroxyhydroquinone	15051535
D006923	Hymecromone	Hymecromone inhibits the reaction [Dietary Fats results in increased activity of CYP2E1 protein]	24661945
C058309	hypaconitine	CYP2E1 protein results in increased metabolism of hypaconitine	21550385
C021304	hyperoside	hyperoside inhibits the reaction [Acetaminophen results in decreased activity of CYP2E1 protein]	26772156
C021304	hyperoside	hyperoside results in decreased activity of CYP2E1 protein	26772156
C029899	imidazole	imidazole results in increased expression of CYP2E1 protein	3337723
D007093	Imidazoles	Imidazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D007213	Indomethacin	Indomethacin results in decreased expression of CYP2E1 mRNA	16771604
C015293	indopan	indopan analog results in decreased activity of CYP2E1 protein	26599973
C015293	indopan	[indopan analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C015293	indopan	indopan results in decreased activity of CYP2E1 protein	26599973
C015293	indopan	[indopan results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D007510	Isatin	Isatin results in increased expression of CYP2E1 mRNA	15056799
C022246	isobutyronitrile	CYP2E1 protein results in increased susceptibility to isobutyronitrile	22051853
C040920	isoliquiritigenin	isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]	25450236
C040920	isoliquiritigenin	isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	25450236
D007538	Isoniazid	CYP2E1 gene polymorphism affects the susceptibility to Isoniazid	12668988
D007538	Isoniazid	CYP2E1 gene SNP affects the susceptibility to Isoniazid	20485159
D007538	Isoniazid	CYP2E1 protein results in increased metabolism of Isoniazid	17950035
D007538	Isoniazid	CYP2E1 protein results in increased susceptibility to Isoniazid	28762043
D007538	Isoniazid	GSTM1 protein inhibits the reaction [CYP2E1 protein results in increased susceptibility to Isoniazid]	28762043
D007538	Isoniazid	Isoniazid results in increased expression of CYP2E1 protein	8074729
D007538	Isoniazid	Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA]	22342832
D007538	Isoniazid	Isoniazid results in increased expression of CYP2E1 mRNA	22342832
D007538	Isoniazid	2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]	9065729
D007538	Isoniazid	diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]	26880746
D007538	Isoniazid	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein	27919644
D007538	Isoniazid	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA	27919644
D007538	Isoniazid	Isoniazid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D007538	Isoniazid	Isoniazid results in increased activity of CYP2E1 protein	12458634\|1513284
D007538	Isoniazid	[Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene	9051121
D007538	Isoniazid	Isoniazid results in increased expression of and results in increased activity of CYP2E1 protein	18754103
D007538	Isoniazid	Isoniazid results in increased expression of CYP2E1	20566340
D007538	Isoniazid	Isoniazid results in increased expression of CYP2E1 mRNA	11752103\|2568303
D007538	Isoniazid	Isoniazid results in increased expression of CYP2E1 protein	15205388\|1576354
D007538	Isoniazid	[Isoniazid results in increased expression of CYP2E1] which results in increased metabolism of Acetaminophen	20566340
D007538	Isoniazid	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D007538	Isoniazid	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D007538	Isoniazid	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D007538	Isoniazid	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D007538	Isoniazid	Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]	15132840
D007538	Isoniazid	Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]	12458634
D007538	Isoniazid	Tiopronin inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]	19683030
D007538	Isoniazid	Isoniazid results in decreased activity of CYP2E1 protein	7710944
D007538	Isoniazid	Isoniazid results in increased activity of CYP2E1	12803597
D007538	Isoniazid	Isoniazid results in increased expression of CYP2E1	15890479
D007545	Isoproterenol	Isoproterenol affects the expression of CYP2E1 mRNA	18725507
C028904	isoproturon	isoproturon inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
C028904	isoproturon	isoproturon results in decreased activity of CYP2E1 protein	22634058
D007546	Isoquinolines	Isoquinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D007546	Isoquinolines	[CYP2E1 protein co-treated with Acetylcysteine] affects the metabolism of Isoquinolines	21395287
D007559	Ivermectin	Ivermectin results in decreased activity of CYP2E1 protein	18420780
C098607	JP8 aviation fuel	CYP2E1 gene polymorphism affects the susceptibility to JP8 aviation fuel	21961652
C098607	JP8 aviation fuel	JP8 aviation fuel results in increased expression of CYP2E1 mRNA	15618438
C098607	JP8 aviation fuel	JP8 aviation fuel results in increased expression of CYP2E1 protein	15618438
C053401	kahweol	kahweol results in decreased activity of CYP2E1 protein	17590492
D007649	Ketamine	Ketamine results in increased expression of CYP2E1 protein	16076768
D007654	Ketoconazole	Ketoconazole results in decreased activity of CYP2E1 protein	15618748
C011890	kojic acid	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA	18544905
C047781	lamotrigine	CYP2E1 protein results in increased glutathionylation of lamotrigine	19961160
C047781	lamotrigine	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased glutathionylation of lamotrigine]	19961160
D007848	Laurates	[CYP2E1 protein co-treated with POR protein] results in increased hydroxylation of Laurates	2292581
C030358	lauric acid	CYP2E1 protein results in increased metabolism of lauric acid	12464242
C052901	lemongrass oil	lemongrass oil affects the expression of CYP2E1 mRNA	25976427
C052901	lemongrass oil	lemongrass oil results in increased expression of CYP2E1 mRNA	25660481
C032854	leupeptin	leupeptin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C070840	licochalcone A	licochalcone A affects the activity of CYP2E1 protein	26100226
D001556	Lindane	CYP2E1 protein results in decreased susceptibility to Lindane	21458603
D001556	Lindane	Lindane results in decreased expression of CYP2E1 mRNA	20035023
D001556	Lindane	Lindane results in increased activity of CYP2E1 protein	12842176\|1463186
D001556	Lindane	Lindane results in increased expression of CYP2E1 mRNA	17919674\|1798429
D001556	Lindane	Lindane results in increased expression of CYP2E1 protein	12842176\|1463186
D008055	Lipids	Lipids inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]	25445725
D008070	Lipopolysaccharides	Lipopolysaccharides affects the reaction [CYP2E1 protein results in increased metabolism of Dimethylnitrosamine]	16235733
D008070	Lipopolysaccharides	[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP2E1 mRNA	22777745
D008070	Lipopolysaccharides	[AQP4 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of CYP2E1 mRNA	20615459
C512196	liquiritin	[brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein	21800547
D008095	Lithocholic Acid	Lithocholic Acid results in decreased activity of CYP2E1 protein	18420780
D047311	Luteolin	Luteolin inhibits the reaction [Cisplatin results in increased expression of CYP2E1 protein]	23770416
C520284	Ly-364947	Ly-364947 inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 mRNA]	25566828
C520284	Ly-364947	Ly-364947 inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	25566828
C520284	Ly-364947	Ly-364947 results in increased expression of CYP2E1 mRNA	25566828
C015329	lycopene	lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA]	26775023
D008294	Malathion	Malathion inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
D008294	Malathion	Malathion results in decreased activity of CYP2E1 protein	22634058
C015977	malealdehyde	1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]	21842885
C015977	malealdehyde	[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde	21842885
C015977	malealdehyde	[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde	21842885
C015977	malealdehyde	[CYP2E1 protein results in increased metabolism of furan] which results in increased chemical synthesis of malealdehyde	22240984\|2418370
C037938	mandelic acid	CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid]	25562543
D008344	Maneb	[Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA	16510128
D008344	Maneb	Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]	20964710
D008344	Maneb	Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	20964710
D008344	Maneb	[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein	20964710
D008344	Maneb	[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA	20964710
D008344	Maneb	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]	20964710
D008344	Maneb	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	20964710
D008344	Maneb	Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D008344	Maneb	Acetylcysteine inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D008344	Maneb	Acetylcysteine inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]	23159886
D008344	Maneb	Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	23159886
D008344	Maneb	[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein	23159886
D008344	Maneb	[Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA	23159886
D008344	Maneb	Maneb results in decreased activity of CYP2E1 protein	11043497
D008344	Maneb	Maneb results in increased activity of CYP2E1 protein	20888808
D008344	Maneb	Maneb results in increased expression of and results in increased activity of CYP2E1 protein	23159886
D008344	Maneb	Maneb results in increased expression of CYP2E1 mRNA	20888808\|2315988
D008344	Maneb	Maneb results in increased expression of CYP2E1 protein	20888808
D008344	Maneb	Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D008344	Maneb	Silymarin inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D008344	Maneb	Silymarin inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]	23159886
D008344	Maneb	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	23159886
C013592	mangiferin	mangiferin results in decreased activity of CYP2E1 protein	18053976
D008550	Melatonin	Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]	20964710
D008550	Melatonin	Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	20964710
D008550	Melatonin	Melatonin inhibits the reaction [Benzene results in increased activity of CYP2E1 protein]	20338863
D008617	Mephenytoin	Mephenytoin results in decreased activity of CYP2E1 protein	18420780
D008627	Mercuric Chloride	Mercuric Chloride results in decreased expression of CYP2E1 mRNA	22792809
D008687	Metformin	Metformin results in increased expression of CYP2E1 mRNA	22342832
C008385	methacrylonitrile	CYP2E1 protein results in increased metabolism of methacrylonitrile	10215687
C008385	methacrylonitrile	[CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides	15893539
C008385	methacrylonitrile	methacrylonitrile results in increased activity of CYP2E1 protein	11939710
C008385	methacrylonitrile	methacrylonitrile results in increased expression of CYP2E1 mRNA	11939710
C008385	methacrylonitrile	methacrylonitrile results in increased expression of CYP2E1 protein	11939710
D008694	Methamphetamine	CYP2E1 protein affects the metabolism of Methamphetamine metabolite	16038959
D008701	Methapyrilene	Methapyrilene results in decreased expression of CYP2E1 mRNA	28935588
D008715	Methionine	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of CYP2E1 mRNA	22872676
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CYP2E1 protein	18952117
D008715	Methionine	RXRA gene mutant form inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased activity of CYP2E1 protein]	18952117
D008715	Methionine	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D008715	Methionine	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D008715	Methionine	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D008715	Methionine	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D003915	Dextromethorphan	Dextromethorphan results in decreased activity of CYP2E1 protein	18420780
D008731	Methoxychlor	Methoxychlor results in decreased activity of CYP2E1 protein	18420780
D008731	Methoxychlor	[Genistein co-treated with Methoxychlor] results in increased expression of CYP2E1 mRNA	21782745
D008731	Methoxychlor	Methoxychlor results in increased expression of and results in increased activity of CYP2E1 protein	12919727
D008731	Methoxychlor	Methoxychlor results in increased expression of CYP2E1 mRNA	21782745
D008732	Methoxydimethyltryptamines	Methoxydimethyltryptamines analog results in decreased activity of CYP2E1 protein	26599973
D008732	Methoxydimethyltryptamines	[Methoxydimethyltryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
D008733	Methoxyflurane	CYP2E1 protein results in increased metabolism of Methoxyflurane	7879937
D008730	Methoxsalen	Methoxsalen results in decreased activity of CYP2E1 protein	18420780
D008730	Methoxsalen	Methoxsalen results in decreased activity of CYP2E1 protein	15879494
D008737	Methyl Chloride	CYP2E1 protein results in increased oxidation of Methyl Chloride	1664256
D008748	Methylcholanthrene	Methylcholanthrene results in decreased expression of CYP2E1 mRNA	28673560
D008748	Methylcholanthrene	[Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA	8734847
D008748	Methylcholanthrene	[Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein	8734847
D008748	Methylcholanthrene	[Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein	8734847
D008748	Methylcholanthrene	[Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein	8734847
D008748	Methylcholanthrene	Methylcholanthrene promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene]	1994898
D008748	Methylcholanthrene	Methylcholanthrene results in decreased activity of CYP2E1 protein	8734847
D008748	Methylcholanthrene	Methylcholanthrene results in decreased expression of CYP2E1 mRNA	7493548\|8734847
D008748	Methylcholanthrene	Methylcholanthrene results in decreased expression of CYP2E1 protein	3113478\|8734847\|
D008748	Methylcholanthrene	[Methylcholanthrene results in decreased expression of CYP2E1 protein] which affects the metabolism of Benzene	9118891
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP2E1 mRNA	19889059\|2327357
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of CYP2E1 protein	10476907\|1988905
D008748	Methylcholanthrene	[protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein	15302093
D008748	Methylcholanthrene	[pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA	8734847
D008748	Methylcholanthrene	[pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein	8734847
D008748	Methylcholanthrene	[pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein	8734847
D008748	Methylcholanthrene	[pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein	8734847
D008752	Methylene Chloride	CYP2E1 protein results in increased oxidation of Methylene Chloride	1664256
D008752	Methylene Chloride	3-xylene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]	8889796
D008752	Methylene Chloride	Benzene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]	8889796
D008752	Methylene Chloride	CYP2E1 protein results in increased metabolism of Methylene Chloride	8889796
D008752	Methylene Chloride	Toluene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]	8889796
C005222	methylethyl ketone	CYP2E1 gene mutant form affects the susceptibility to methylethyl ketone	21352904
C017510	methylethylnitrosamine	CYP2E1 protein affects the metabolism of and results in increased activity of methylethylnitrosamine	11600130
C002950	methylformamide	CYP2E1 protein results in increased metabolism of methylformamide	1538706
C002950	methylformamide	4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
C002950	methylformamide	CYP2E1 protein results in increased metabolism of methylformamide	1538706
C002950	methylformamide	Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
C002950	methylformamide	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
C002950	methylformamide	fomepizole promotes the reaction [CYP2E1 protein results in increased metabolism of methylformamide]	1538706
D012862	Skatole	Skatole results in decreased expression of CYP2E1 mRNA	28571685
D008767	Methylmercury Compounds	Methylmercury Compounds results in decreased expression of CYP2E1 mRNA	22792809
D018817	N-Methyl-3,4-methylenedioxyamphetamine	"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CYP2E1 mRNA"	26251327
D015655	1-Methyl-4-phenylpyridinium	[AQP4 protein affects the susceptibility to 1-Methyl-4-phenylpyridinium] which affects the expression of CYP2E1 mRNA	20615459
D008777	Methyltestosterone	[Methyltestosterone co-treated with Cholic Acids] affects the expression of CYP2E1 mRNA	27344345
D008874	Midazolam	CYP2E1 protein results in increased metabolism of Midazolam	17590308
D008917	Mirex	Mirex results in decreased expression of CYP2E1 protein	3113478
C502230	Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin	"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]"	12086689
C502230	Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin	"Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin promotes the reaction [CYP2E1 protein results in increased susceptibility to Buthionine Sulfoximine]"	12086689
C028577	monobutyl phthalate	monobutyl phthalate results in decreased activity of CYP2E1 protein	27432241
D008999	Monocrotophos	[Monocrotophos co-treated with Cimetidine] results in increased expression of CYP2E1 protein	22733800
D008999	Monocrotophos	Monocrotophos promotes the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	24663500
D008999	Monocrotophos	Monocrotophos promotes the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	24663500
D008999	Monocrotophos	Monocrotophos results in increased activity of CYP2E1 protein	22733800
D008999	Monocrotophos	Monocrotophos results in increased expression of CYP2E1 mRNA	22733800\|2466350
D008999	Monocrotophos	Monocrotophos results in increased expression of CYP2E1 protein	22733800
D008999	Monocrotophos	[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein	22733800
D008999	Monocrotophos	[Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA	22733800
D008999	Monocrotophos	[Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein	22733800
D008999	Monocrotophos	Monocrotophos results in increased expression of CYP2E1 protein	21445290
C005939	muconic acid	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of muconic acid	15051535
C008577	myricitrin	myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein]	25656916
C534983	N-(2-amino-3-methyl-n-butyl)-3-((bis-4-fluorophenyl)methoxy)tropane	CYP2E1 protein results in increased metabolism of N-(2-amino-3-methyl-n-butyl)-3-((bis-4-fluorophenyl)methoxy)tropane	18425847
C028473	N-acetyl-4-benzoquinoneimine	CYP2E1 protein results in increased abundance of N-acetyl-4-benzoquinoneimine	24661219
C028473	N-acetyl-4-benzoquinoneimine	CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine	20566340
C028473	N-acetyl-4-benzoquinoneimine	CYP2E1 protein results in increased chemical synthesis of and results in increased abundance of N-acetyl-4-benzoquinoneimine	19679878
C028473	N-acetyl-4-benzoquinoneimine	CYP2E1 results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine	20566340
C028473	N-acetyl-4-benzoquinoneimine	CYP2E1 protein results in increased abundance of N-acetyl-4-benzoquinoneimine	20166895\|2040409
C028473	N-acetyl-4-benzoquinoneimine	CYP2E1 protein results in increased chemical synthesis of N-acetyl-4-benzoquinoneimine	20423716
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of CYP2E1 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of CYP2E1 mRNA"	25554681
C031721	naphthalene	naphthalene results in increased expression of CYP2E1 mRNA	20500019
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in decreased expression of CYP2E1 mRNA	15913567
C461488	N-benzylpiperazine	N-benzylpiperazine results in decreased expression of CYP2E1 mRNA	26821219
C051752	nefazodone	nefazodone results in increased expression of CYP2E1 mRNA	24136188
C026385	n-hexane	CYP2E1 gene polymorphism affects the susceptibility to n-hexane	16484137
C026385	n-hexane	CYP2E1 protein results in increased hydroxylation of n-hexane	16484137
C026385	n-hexane	CYP2E1 protein results in increased metabolism of n-hexane	11201664
C026385	n-hexane	diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]	28115069
C026385	n-hexane	n-hexane results in increased expression of and results in increased activity of CYP2E1 protein	28115069
C028007	nickel monoxide	nickel monoxide results in decreased expression of CYP2E1 mRNA	19167457
D009538	Nicotine	Nicotine results in increased expression of CYP2E1 protein	16368115
D009538	Nicotine	Nicotine results in increased expression of CYP2E1 protein	16434548
D009538	Nicotine	Nicotine results in decreased activity of CYP2E1 protein	25221795
D009543	Nifedipine	Nifedipine results in decreased activity of CYP2E1 protein	18420780
D009569	Nitric Oxide	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Nitric Oxide	18845238
D005996	Nitroglycerin	Nitroglycerin results in increased expression of CYP2E1 mRNA	12102619
D009602	Nitrosamines	[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to Nitrosamines	11733072
D009602	Nitrosamines	CYP2E1 protein results in increased metabolism of and results in increased activity of Nitrosamines	16470306
C014707	nitrosobenzylmethylamine	CYP2E1 protein affects the metabolism of nitrosobenzylmethylamine	2655891
C014707	nitrosobenzylmethylamine	CYP2E1 protein results in increased metabolism of nitrosobenzylmethylamine	10616189
C014707	nitrosobenzylmethylamine	[Ethanol co-treated with nitrosobenzylmethylamine] results in increased expression of CYP2E1 protein	16704527
D009242	N-Nitrosopyrrolidine	CYP2E1 protein affects the metabolism of and results in increased activity of N-Nitrosopyrrolidine	11774366
C468271	N-methyl-N-benzylnitrosamine	N-methyl-N-benzylnitrosamine results in decreased activity of CYP2E1 protein	12222751
C014102	N-methyl-N-nitrosoaniline	CYP2E1 protein affects the metabolism of N-methyl-N-nitrosoaniline	15815077
C014102	N-methyl-N-nitrosoaniline	N-methyl-N-nitrosoaniline binds to CYP2E1 protein	15815077
C578955	N,N-diallyl-5-methoxytryptamine	"N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2E1 protein"	26599973
C578955	N,N-diallyl-5-methoxytryptamine	"[N,N-diallyl-5-methoxytryptamine results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone"	26599973
C454677	N,N-diethyl-3-hydroxymethylbenzamide	"CYP2E1 protein results in increased chemical synthesis of N,N-diethyl-3-hydroxymethylbenzamide"	11854147
C033695	N,N-diisopropyltryptamine	"N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein"	26599973
C033695	N,N-diisopropyltryptamine	"[N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone"	26599973
C014129	N-nitrosodiethanolamine	CYP2E1 protein results in increased metabolism of N-nitrosodiethanolamine	18616954
C013161	N-nitroso(di-n-propyl)amine	CYB5A protein promotes the reaction [CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine]	15728263
C013161	N-nitroso(di-n-propyl)amine	CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine	10910959
C013161	N-nitroso(di-n-propyl)amine	[CYP2E1 protein co-treated with POR protein co-treated with CYB5B protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine	11733072
C013161	N-nitroso(di-n-propyl)amine	[CYP2E1 protein co-treated with POR protein] results in increased susceptibility to N-nitroso(di-n-propyl)amine	11035158
C013161	N-nitroso(di-n-propyl)amine	CYP2E1 protein results in increased activity of N-nitroso(di-n-propyl)amine	15728263
C013161	N-nitroso(di-n-propyl)amine	CYP2E1 protein affects the metabolism of N-nitroso(di-n-propyl)amine	10910959
C013161	N-nitroso(di-n-propyl)amine	CYP2E1 protein results in decreased nitrosation of N-nitroso(di-n-propyl)amine	10910959
C013161	N-nitroso(di-n-propyl)amine	CYP2E1 protein results in increased metabolism of N-nitroso(di-n-propyl)amine	8625499
C002741	N-nitrosomorpholine	CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosomorpholine	11774366
C002743	N-nitrosopiperidine	CYP2E1 protein affects the metabolism of and results in increased activity of N-nitrosopiperidine	11774366
C572573	N-nitroso-tris-chloroethylurea	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA	27935865
C572573	N-nitroso-tris-chloroethylurea	[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYP2E1 mRNA	27935865
C093285	NOC 18	NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA]	18206661
C063006	norflurane	4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased oxidation of norflurane]	1356728
C063006	norflurane	CYP2E1 protein results in increased oxidation of norflurane	1356728
C010262	norharman	CYP2E1 protein affects the metabolism of [norharman co-treated with aniline]	15279827
C041288	n-propyl disulfide	n-propyl disulfide results in decreased activity of CYP2E1 protein	18339364
C464660	obeticholic acid	obeticholic acid results in decreased expression of CYP2E1 mRNA	27939613
C025589	ochratoxin A	CYP2E1 protein results in increased susceptibility to ochratoxin A	11189750
D019787	Linoleic Acid	Linoleic Acid results in decreased activity of CYP2E1 protein	16978661
D019301	Oleic Acid	Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA]	26854922
D019301	Oleic Acid	[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	26854922
D019301	Oleic Acid	[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA	26854922
D019319	Okadaic Acid	Okadaic Acid results in decreased expression of CYP2E1 mRNA	25270620
D009828	Oleanolic Acid	Oleanolic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased activity of CYP2E1 protein]	10355542
D009828	Oleanolic Acid	Oleanolic Acid results in decreased expression of CYP2E1 mRNA	18706400
D009828	Oleanolic Acid	Oleanolic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	25111957
D009828	Oleanolic Acid	Oleanolic Acid results in decreased expression of CYP2E1 mRNA	18706400
C026209	oltipraz	oltipraz affects the activity of CYP2E1 protein	10775323
D009853	Omeprazole	Omeprazole results in increased expression of and results in increased activity of CYP2E1 protein	15802389
D009966	Orphenadrine	Orphenadrine inhibits the reaction [CYP2E1 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]	9241656
D009966	Orphenadrine	Orphenadrine inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]	9241656
D009966	Orphenadrine	Orphenadrine results in decreased activity of CYP2E1 protein	9241656
D010098	Oxycodone	Oxycodone results in increased expression of CYP2E1 mRNA	23439660
D010100	Oxygen	Oxygen deficiency results in decreased expression of CYP2E1 mRNA	19695866
D010100	Oxygen	Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D010100	Oxygen	Ethanol promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D010100	Oxygen	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA]	26747958
D010100	Oxygen	Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein]	26747958
D010100	Oxygen	Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D010100	Oxygen	Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D010100	Oxygen	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA	26747958
D010100	Oxygen	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 protein	26747958
D010100	Oxygen	[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 mRNA	26747958
D010100	Oxygen	[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased expression of CYP2E1 protein	26747958
D010100	Oxygen	[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA	26747958
D010100	Oxygen	[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein	26747958
D010100	Oxygen	zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
D010100	Oxygen	zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D010126	Ozone	Ozone results in decreased expression of CYP2E1 mRNA	12763052
D017239	Paclitaxel	Paclitaxel results in decreased activity of CYP2E1 protein	24882083
D017239	Paclitaxel	turmeric extract affects the reaction [Paclitaxel results in decreased activity of CYP2E1 protein]	24882083
D019308	Palmitic Acid	Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA]	26854922
D019308	Palmitic Acid	[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	26854922
D019308	Palmitic Acid	[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA	26854922
D000073878	Palm Oil	Palm Oil results in decreased expression of CYP2E1 mRNA	18042831
D010269	Paraquat	[Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA	16510128
D010269	Paraquat	Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]	20964710
D010269	Paraquat	Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	20964710
D010269	Paraquat	[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein	20964710
D010269	Paraquat	[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA	20964710
D010269	Paraquat	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]	20964710
D010269	Paraquat	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	20964710
D010269	Paraquat	Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D010269	Paraquat	Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	23159886
D010269	Paraquat	Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D010269	Paraquat	Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]	23159886
D010269	Paraquat	[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein	23159886
D010269	Paraquat	[Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA	23159886
D010269	Paraquat	Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA]	20553223
D010269	Paraquat	Paraquat results in increased activity of CYP2E1 protein	20888808
D010269	Paraquat	Paraquat results in increased expression of and results in increased activity of CYP2E1 protein	23159886
D010269	Paraquat	Paraquat results in increased expression of CYP2E1 mRNA	20553223\|2088880
D010269	Paraquat	Paraquat results in increased expression of CYP2E1 protein	20888808
D010269	Paraquat	Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D010269	Paraquat	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	23159886
D010269	Paraquat	Silymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D010269	Paraquat	Silymarin inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]	23159886
D010269	Paraquat	Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA]	20553223
D010278	Parathion	CYP2E1 protein affects the metabolism of Parathion	12669189
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP2E1 mRNA	18952161
D052638	Particulate Matter	Particulate Matter results in increased expression of CYP2E1 mRNA	22352393\|2421647
D010396	Penicillamine	Penicillamine results in increased expression of CYP2E1 mRNA	22843330
C003060	pentachlorobenzene	CYP2E1 protein results in increased metabolism of pentachlorobenzene	7747284
C003060	pentachlorobenzene	CYP2E1 protein results in increased oxidation of pentachlorobenzene	7747284
C003060	pentachlorobenzene	pentachlorobenzene results in increased expression of CYP2E1 protein	10696772
D010416	Pentachlorophenol	CYP2E1 protein results in increased oxidation of Pentachlorophenol	7747284
D010416	Pentachlorophenol	Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-hydroxymethylpyrene] which results in increased mutagenesis of HPRT1 gene]	25243916
D010416	Pentachlorophenol	Pentachlorophenol inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]	25243916
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid inhibits the reaction [CYP2E1 protein results in increased oxidation of Chlorzoxazone]	21964418
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid affects the expression of CYP2E1 mRNA	19429403
C023036	perfluorooctanoic acid	"Dietary Fats, Unsaturated inhibits the reaction [perfluorooctanoic acid results in increased expression of CYP2E1 mRNA]"	23626681
C023036	perfluorooctanoic acid	perfluorooctanoic acid affects the expression of CYP2E1 mRNA	19429403
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of CYP2E1 mRNA	17681415
D010575	Pesticides	CYP2E1 gene polymorphism affects the susceptibility to Pesticides	18550589
D010575	Pesticides	CYP2E1 protein results in decreased susceptibility to Pesticides	21458603
D010575	Pesticides	CYP2E1 protein results in increased susceptibility to Pesticides	18550589
D010615	Phenacetin	CYP2E1 protein affects the metabolism of Phenacetin	15879494
C031181	phenanthrene	CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene	19766613
C031181	phenanthrene	CYP2E1 protein results in increased metabolism of and results in increased activity of phenanthrene	19766613
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate results in decreased activity of CYP2E1 protein	10616189
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]	7601153
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]	7601153
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde]	7562599
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	7562599
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	7562599
C058305	phenethyl isothiocyanate	phenethyl isothiocyanate results in decreased expression of CYP2E1 protein	7601153
D010634	Phenobarbital	Phenobarbital results in decreased expression of CYP2E1 mRNA	19952500
D010634	Phenobarbital	Choline deficiency promotes the reaction [Phenobarbital results in increased expression of CYP2E1 protein]	18798224
D010634	Phenobarbital	Phenobarbital results in decreased expression of CYP2E1 mRNA	15596064\|1738113
D010634	Phenobarbital	Phenobarbital results in decreased expression of CYP2E1 protein	9118891
D010634	Phenobarbital	Phenobarbital results in increased activity of CYP2E1 protein	15490126
D010634	Phenobarbital	Phenobarbital results in increased expression of CYP2E1 mRNA	23273579
D010634	Phenobarbital	Phenobarbital results in increased expression of CYP2E1 protein	18798224
D019800	Phenol	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of Phenol	15051535
D019800	Phenol	CYP2E1 protein results in increased metabolism of Phenol	11701230
D019800	Phenol	[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol	8211999
D019800	Phenol	CYP2E1 protein results in increased metabolism of Phenol	8211999
D019800	Phenol	[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol	8211999
D019800	Phenol	[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone	8211999
D019800	Phenol	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol]	8211999
D019800	Phenol	EPHX1 protein promotes the reaction [CYP2E1 protein results in increased metabolism of Phenol]	8211999
D019800	Phenol	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol]	8211999
D019800	Phenol	EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone]	8211999
D019800	Phenol	[Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]	8211999
C008838	phenthoate	phenthoate inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
C008838	phenthoate	phenthoate results in decreased activity of CYP2E1 protein	22634058
D010626	Phenylethyl Alcohol	CYP2E1 protein results in increased oxidation of Phenylethyl Alcohol	7515681
C012482	phenylglyoxylic acid	CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid]	25562543
D010672	Phenytoin	NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA]	18206661
D010672	Phenytoin	Phenytoin results in increased expression of CYP2E1 mRNA	18206661
D010672	Phenytoin	Phenytoin results in increased expression of CYP2E1 protein	18206661
D010672	Phenytoin	Phenytoin results in decreased expression of CYP2E1 mRNA	17381134
D009764	o-Phthalaldehyde	o-Phthalaldehyde results in decreased expression of CYP2E1 mRNA	20112102
C060836	pioglitazone	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA	27935865
C448623	pipermethystine	pipermethystine results in increased expression of CYP2E1 protein	17329236
D010936	Plant Extracts	Plant Extracts results in decreased activity of CYP2E1 protein	15900287\|2082860
D010936	Plant Extracts	Plant Extracts results in decreased expression of CYP2E1 mRNA	24446304
D010936	Plant Extracts	Plant Extracts results in increased activity of CYP2E1 protein	15974642
D010936	Plant Extracts	Plant Extracts results in increased expression of CYP2E1 mRNA	15629189
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	23279844\|2399409
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	28797650
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	21224420
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	21224420
D010936	Plant Extracts	Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CYP2E1 protein]	19551842
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	22525864
D010936	Plant Extracts	Plant Extracts promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]	26332274
D010936	Plant Extracts	Plant Extracts results in decreased expression of CYP2E1 mRNA	15242186
D010936	Plant Extracts	Plant Extracts results in increased expression of CYP2E1 mRNA	20521779\|2633227
D010936	Plant Extracts	Plant Extracts results in increased expression of CYP2E1 protein	20521779
D028321	Plant Preparations	[Estradiol co-treated with Plant Preparations] results in decreased expression of CYP2E1 mRNA	26945725
D028321	Plant Preparations	Plant Preparations results in decreased activity of CYP2E1 protein	27697540
D028321	Plant Preparations	Plant Preparations results in decreased expression of CYP2E1 mRNA	26945725\|2769754
D028321	Plant Preparations	Plant Preparations results in increased expression of CYP2E1 mRNA	18047722
D028321	Plant Preparations	Plant Preparations results in increased expression of CYP2E1 mRNA	21056093
D059808	Polyphenols	Polyphenols results in decreased expression of CYP2E1 mRNA	19370779
D059808	Polyphenols	Polyphenols results in decreased expression of CYP2E1 protein	19370779
D059808	Polyphenols	Polyphenols results in decreased expression of CYP2E1 mRNA	16293270
D011134	Polysaccharides	Polysaccharides results in decreased activity of CYP2E1 protein	17827724
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of CYP2E1 mRNA	23608068
D011319	Primaquine	[CYP2E1 protein results in increased expression of HBG2 protein] which affects the susceptibility to Primaquine	19616568
D011319	Primaquine	CYP2E1 protein results in increased metabolism of Primaquine	19616568
D011335	Proadifen	Proadifen inhibits the reaction [CYP2E1 protein results in increased metabolism of aniline]	8819299
D011335	Proadifen	Proadifen results in decreased activity of CYP2E1 protein	15618748
C045362	prochloraz	prochloraz results in decreased expression of CYP2E1 mRNA	20035023
C035988	procymidone	procymidone results in increased expression of and results in increased activity of CYP2E1 protein	12787915
C035988	procymidone	procymidone results in increased expression of CYP2E1 mRNA	12787915
C024273	profenofos	profenofos inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	22634058
C024273	profenofos	profenofos results in decreased activity of CYP2E1 protein	22634058
D011374	Progesterone	Progesterone affects the expression of CYP2E1 mRNA	17251523
D011374	Progesterone	Progesterone results in decreased expression of CYP2E1 mRNA	19690047
D011374	Progesterone	Progesterone promotes the reaction [Benzene results in decreased activity of CYP2E1 protein]	18407866
D019840	2-Propanol	2-Propanol binds to and results in increased expression of CYP2E1 protein	3337723
D019840	2-Propanol	2-Propanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D019840	2-Propanol	2-Propanol results in increased expression of CYP2E1 protein	9118891
D019840	2-Propanol	2-Propanol results in decreased activity of CYP2E1 protein	7710944
C028255	propargyl alcohol	CYP2E1 protein results in increased metabolism of propargyl alcohol	11306107
C035967	propetamphos	[cypermethrin co-treated with propetamphos] results in increased activity of CYP2E1 protein	25926273
C035967	propetamphos	propetamphos results in increased activity of CYP2E1 protein	25926273
C045950	propiconazole	propiconazole results in decreased expression of CYP2E1 protein	7986207
D011429	Propolis	Propolis inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein]	17410408
C004765	propylene dichloride	CYP2E1 protein results in increased oxidation of propylene dichloride	1664256
C006068	propylparaben	propylparaben results in decreased activity of CYP2E1 protein	27432241
C009091	protocatechuic acid	[protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein	15302093
C009091	protocatechuic acid	protocatechuic acid results in decreased activity of CYP2E1 protein	15302093
C033607	puerarin	puerarin inhibits the reaction [CYP2E1 protein results in increased hydroxylation of aniline]	18038910
C033607	puerarin	puerarin results in increased expression of CYP2E1 protein	18038910
C511975	purpurin	purpurin results in decreased activity of CYP2E1 protein	12379470
C026133	purpurogallin	purpurogallin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D011718	Pyrazinamide	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein	27919644
D011718	Pyrazinamide	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA	27919644
D011718	Pyrazinamide	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D011718	Pyrazinamide	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D011718	Pyrazinamide	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D011718	Pyrazinamide	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D011719	Pyrazines	allyl sulfide inhibits the reaction [Pyrazines results in increased activity of CYP2E1 protein]	8117321
D011719	Pyrazines	allyl sulfide inhibits the reaction [Pyrazines results in increased expression of CYP2E1 protein]	8117321
D011719	Pyrazines	Pyrazines results in increased activity of CYP2E1 protein	8117321
D011719	Pyrazines	Pyrazines results in increased expression of CYP2E1 protein	8117321
C031280	pyrazole	pyrazole results in increased expression of CYP2E1 protein	8074729
C031280	pyrazole	pyrazole affects the expression of CYP2E1 protein	19679878
C031280	pyrazole	pyrazole results in increased expression of CYP2E1 protein	9698299
C031280	pyrazole	pyrazole results in increased activity of CYP2E1 protein	3782137\|8734847
C031280	pyrazole	pyrazole results in increased expression of CYP2E1 protein	3113478\|3782137\|
C031280	pyrazole	pyrazole results in increased activity of CYP2E1 protein	10995255
D011720	Pyrazoles	Pyrazoles inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
C023666	pyridine	CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]	12147272
C023666	pyridine	Dimethyl Sulfoxide inhibits the reaction [CYP2E1 protein promotes the reaction [pyridine results in increased expression of CYP1A1 mRNA]]	12147272
C023666	pyridine	pyridine results in decreased activity of CYP2E1 protein	12464242
C023666	pyridine	pyridine results in increased expression of CYP2E1 protein	8074729
C023666	pyridine	pyridine results in increased expression of CYP2E1 protein	8246169
C023666	pyridine	Cycloheximide inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]	1968335
C023666	pyridine	Cycloheximide inhibits the reaction [pyridine results in increased expression of CYP2E1 protein]	1968335
C023666	pyridine	Ditiocarb inhibits the reaction [pyridine results in increased activity of CYP2E1 protein]	9618253
C023666	pyridine	INS protein affects the reaction [pyridine results in increased expression of CYP2E1 protein]	10215695
C023666	pyridine	[pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA	8734847
C023666	pyridine	[pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein	8734847
C023666	pyridine	[pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein	8734847
C023666	pyridine	[pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein	8734847
C023666	pyridine	pyridine promotes the reaction [ciprofibrate results in increased expression of CYP2E1 protein]	7587954
C023666	pyridine	pyridine promotes the reaction [CYP2E1 protein results in increased hydroxylation of 4-nitrophenol]	9618253
C023666	pyridine	pyridine results in increased activity of CYP2E1 protein	11181506\|1291972
C023666	pyridine	pyridine results in increased expression of CYP2E1 mRNA	1379807\|2241968
C023666	pyridine	pyridine results in increased expression of CYP2E1 protein	10215695\|1118150
C013229	pyridine N-oxide	pyridine N-oxide results in increased expression of CYP2E1 protein	1379807
D011725	Pyridines	Pyridines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
D011748	Pyrogallol	Pyrogallol results in increased activity of CYP2E1 protein	18789925
D011748	Pyrogallol	Pyrogallol results in increased expression of CYP2E1 mRNA	18789925
D011748	Pyrogallol	resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP2E1 protein]	18789925
D011748	Pyrogallol	resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP2E1 mRNA]	18789925
D011791	Quartz	Quartz results in decreased expression of CYP2E1 mRNA	19836432
D011794	Quercetin	Quercetin inhibits the reaction [[CYP2E1 protein results in increased susceptibility to Docosahexaenoic Acids] which results in increased phosphorylation of MAP2K4 protein]	16963249
D011794	Quercetin	Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	19325051
D011794	Quercetin	Quercetin results in decreased activity of CYP2E1 protein	28232125
D011794	Quercetin	zinc protoporphyrin inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]]	19325051
D011794	Quercetin	Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	26218279
D011794	Quercetin	Quercetin results in decreased activity of CYP2E1 protein	18420780
D011794	Quercetin	Quercetin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D011794	Quercetin	Quercetin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA]	11306697
D011794	Quercetin	Quercetin promotes the reaction [Dexamethasone results in increased expression of CYP2E1 mRNA]	20501703
D011794	Quercetin	Quercetin promotes the reaction [Dexamethasone results in increased expression of CYP2E1 protein]	20501703
D011796	Quinacrine	Quinacrine binds to and results in decreased activity of CYP2E1 protein	18754103
D011796	Quinacrine	Quinacrine results in decreased expression of CYP2E1 protein	18754103
D011802	Quinidine	Quinidine results in decreased activity of CYP2E1 protein	18420780
C037219	quinoline	CYP2E1 protein results in increased hydroxylation of quinoline	8824525
C037219	quinoline	CYP2E1 protein results in increased hydroxylation of quinoline	8824525
D011804	Quinolines	Quinolines inhibits the reaction [CYP2E1 protein results in increased hydroxylation of Chlorzoxazone]	21600194
C004532	quinone	quinone results in decreased expression of CYP2E1 protein	10462055
D017382	Reactive Oxygen Species	CYP2E1 protein results in increased chemical synthesis of Reactive Oxygen Species	10498651
D017382	Reactive Oxygen Species	[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species	18845238
D017382	Reactive Oxygen Species	[Ethanol co-treated with CYP2E1 protein] results in increased abundance of Reactive Oxygen Species	22222162
D017382	Reactive Oxygen Species	fomepizole inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased abundance of Reactive Oxygen Species]	18845238
D017382	Reactive Oxygen Species	[CYP2E1 protein results in increased hydroxylation of 4-biphenylamine] which results in increased abundance of Reactive Oxygen Species	25601990
D017382	Reactive Oxygen Species	CYP2E1 protein affects the chemical synthesis of Reactive Oxygen Species	14693714
D017382	Reactive Oxygen Species	CYP2E1 protein results in decreased susceptibility to Reactive Oxygen Species	12470497
C059514	resveratrol	resveratrol analog results in decreased activity of CYP2E1 protein	16684708
C059514	resveratrol	resveratrol inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]	25956474
C059514	resveratrol	resveratrol inhibits the reaction [Pyrogallol results in increased activity of CYP2E1 protein]	18789925
C059514	resveratrol	resveratrol inhibits the reaction [Pyrogallol results in increased expression of CYP2E1 mRNA]	18789925
C059514	resveratrol	resveratrol results in decreased activity of CYP2E1 protein	18420780\|2595647
C059514	resveratrol	resveratrol results in increased expression of CYP2E1 mRNA	22610192
C059514	resveratrol	resveratrol affects the expression of CYP2E1 mRNA	15748624
C009166	retinol acetate	[LRAT gene mutant form affects the susceptibility to [bisphenol A co-treated with retinol acetate]] which results in increased expression of CYP2E1 mRNA	28123100
C003300	retrorsine	retrorsine results in increased expression of CYP2E1	24799337
C013672	riddelliine	riddelliine results in increased expression of CYP2E1 mRNA	18047722\|1804772
D012293	Rifampin	[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein	22733800
D012293	Rifampin	[Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA	22733800
D012293	Rifampin	[Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein	22733800
D012293	Rifampin	Rifampin results in decreased expression of CYP2E1 mRNA	22258563
D012293	Rifampin	Rifampin results in increased activity of CYP2E1 protein	18071298
D012293	Rifampin	Rifampin results in increased expression of CYP2E1 mRNA	18071298\|2273380
D012293	Rifampin	Rifampin results in increased expression of CYP2E1 protein	22733800
D012293	Rifampin	[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein	25835148
D012293	Rifampin	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein	27919644
D012293	Rifampin	[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA	27919644
D012293	Rifampin	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D012293	Rifampin	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D012293	Rifampin	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D012293	Rifampin	Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D012293	Rifampin	Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]	15132840
C089730	rosiglitazone	rosiglitazone results in increased expression of CYP2E1 mRNA	21515302
C547390	rossicaside B	rossicaside B inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein]	19793341
C547130	(S)-2-methylbutyronitrile	CYP2E1 protein results in increased susceptibility to (S)-2-methylbutyronitrile	22051853
D012451	Safrole	Safrole results in decreased activity of CYP2E1 protein	15778010
C018142	saiko-keishi-to	saiko-keishi-to results in increased expression of CYP2E1 mRNA	14607025
C076944	salvianolic acid B	salvianolic acid B inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	27989594
D012503	Saponins	Saponins inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 protein]	23994094
D012503	Saponins	Saponins results in decreased expression of CYP2E1 mRNA	26590097
C081294	satraplatin	satraplatin results in decreased activity of CYP2E1 protein	24882083
C034557	schizandrer A	schizandrer A results in decreased activity of CYP2E1 protein	25753323
C015499	schizandrin B	schizandrin B results in decreased activity of CYP2E1 protein	25753323
C031409	schizandrin C	schizandrin C results in decreased activity of CYP2E1 protein	25753323
C033585	schizandrol B	schizandrol B binds to CYP2E1 protein	25319358
C033585	schizandrol B	schizandrol B inhibits the reaction [CYP2E1 protein results in increased metabolism of and results in increased activity of Acetaminophen]	25319358
C033585	schizandrol B	schizandrol B results in decreased activity of CYP2E1 protein	25319358
D012643	Selenium	[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]	21424224
C009237	senecionine	senecionine results in increased expression of CYP2E1 mRNA	26100227
C042431	S-ethyl glutathione	S-ethyl glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene]	16872732
C009250	sevoflurane	CYP2E1 protein results in increased metabolism of sevoflurane	7879937
C016101	shikonin	shikonin results in decreased activity of CYP2E1 protein	28941798
C016101	shikonin	shikonin results in decreased activity of CYP2E1 protein	28941798
C461320	shosaiko-to	shosaiko-to results in increased expression of CYP2E1 mRNA	14607025
D012838	Silymarin	Silymarin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]	28797650
D012838	Silymarin	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]	20964710
D012838	Silymarin	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	20964710
D012838	Silymarin	Silymarin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CYP2E1 protein]	17410408
D012838	Silymarin	Silymarin inhibits the reaction [Carbon Tetrachloride results in increased expression of CYP2E1 mRNA]	24582681
D012838	Silymarin	Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D012838	Silymarin	Silymarin inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D012838	Silymarin	Silymarin inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]	23159886
D012838	Silymarin	Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]	23159886
D012838	Silymarin	Silymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]	23159886
D012838	Silymarin	Silymarin inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]	23159886
D012906	Smoke	Smoke affects the reaction [Toluene affects the methylation of CYP2E1 promoter]	25963742
D012906	Smoke	Smoke inhibits the reaction [CYP2E1 protein affects the metabolism of Styrene]	16125881
D012906	Smoke	Smoke results in increased expression of CYP2E1 mRNA	23693141
C017947	sodium arsenite	CYP2E1 protein results in decreased susceptibility to sodium arsenite	19154403
C017947	sodium arsenite	sodium arsenite results in decreased expression of CYP2E1 mRNA	17350061\|1745185
C017947	sodium arsenite	sodium arsenite results in increased expression of CYP2E1 mRNA	25065748
C028982	sodium chromate(VI)	Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]	1903091
C028982	sodium chromate(VI)	CYP2E1 protein results in increased reduction of sodium chromate(VI)	1903091
C028982	sodium chromate(VI)	Carbon Monoxide inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]	1903091
C028982	sodium chromate(VI)	Carbon Tetrachloride inhibits the reaction [CYP2E1 protein results in increased reduction of sodium chromate(VI)]	1903091
C028982	sodium chromate(VI)	CYP2E1 protein binds to and results in increased reduction of sodium chromate(VI)	1903091
D012982	Sodium, Dietary	"CYP2E1 gene polymorphism affects the susceptibility to Sodium, Dietary"	14696128
D053260	Soot	Soot results in increased expression of CYP2E1 mRNA	26551751
C053003	S-phenyl-N-acetylcysteine	[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of S-phenyl-N-acetylcysteine	15051535
D019311	Staurosporine	Staurosporine inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA]	11306697
D019311	Staurosporine	Staurosporine results in increased expression of CYP2E1 mRNA	11306697
C031183	stearic acid	stearic acid results in increased activity of CYP2E1 protein	26739624
D013311	Streptozocin	Streptozocin results in decreased expression of CYP2E1 protein	12700423
D013311	Streptozocin	[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein	24815820
D013311	Streptozocin	Streptozocin results in increased expression of CYP2E1 mRNA	11752103\|2590577
D013311	Streptozocin	Streptozocin results in increased expression of CYP2E1 protein	14693714
D020058	Styrene	CYP2E1 gene polymorphism affects the metabolism of Styrene	12893075\|2011732
D020058	Styrene	CYP2E1 gene polymorphism affects the susceptibility to Styrene	12604177\|1475167
D020058	Styrene	CYP2E1 gene polymorphism results in decreased metabolism of Styrene	16125881
D020058	Styrene	CYP2E1 gene polymorphism results in increased susceptibility to Styrene	11535253
D020058	Styrene	CYP2E1 protein affects the metabolism of Styrene	12464798
D020058	Styrene	CYP2E1 protein affects the oxidation of Styrene	16872732
D020058	Styrene	CYP2E1 protein results in increased oxidation of Styrene	1664256
D020058	Styrene	CYP2E1 protein results in increased susceptibility to Styrene	16872732
D020058	Styrene	CYP2E1 results in increased metabolism of and results in increased susceptibility to Styrene	22366341
D020058	Styrene	CYP2E1 results in increased metabolism of and results in increased susceptibility to Styrene analog	22366341
D020058	Styrene	[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene	20470765
D020058	Styrene	Glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene]	16872732
D020058	Styrene	GSTM1 protein affects the reaction [CYP2E1 protein affects the metabolism of Styrene]	12464798
D020058	Styrene	S-ethyl glutathione inhibits the reaction [CYP2E1 protein results in increased susceptibility to Styrene]	16872732
D020058	Styrene	Smoke inhibits the reaction [CYP2E1 protein affects the metabolism of Styrene]	16125881
D020058	Styrene	Styrene results in increased expression of CYP2E1 mRNA	21030303
D020058	Styrene	CYP2E1 protein affects the metabolism of Styrene	12746132
D020058	Styrene	CYP2E1 protein results in increased metabolism of Styrene	24320693
D020058	Styrene	CYP2E1 protein results in increased susceptibility to Styrene	15110085
D020058	Styrene	[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene	20470765
D020058	Styrene	[Ditiocarb co-treated with CYP2E1 gene mutant form] results in decreased metabolism of Styrene	12746132
D020058	Styrene	CYP2E1 protein results in increased oxidation of Styrene	26463279
D020058	Styrene	gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA]	18202523
D020058	Styrene	gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein]	18202523
D020058	Styrene	Styrene results in increased expression of CYP2E1 mRNA	16418063\|1820252
D020058	Styrene	Styrene results in increased expression of CYP2E1 protein	16418063\|1820252
C013690	styrene oxide	CYP2E1 results in increased chemical synthesis of styrene oxide	22366341
C013690	styrene oxide	CYP2E1 results in increased chemical synthesis of styrene oxide analog	22366341
D013438	Sulfhydryl Compounds	Sulfhydryl Compounds results in decreased expression of CYP2E1 protein	8117321
C016766	sulforafan	sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]	21684301
C016766	sulforafan	sulforafan inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein]	21684301
C473478	sunitinib	sunitinib results in increased expression of CYP2E1 mRNA	26797788
D014284	Triiodothyronine	Triiodothyronine results in increased activity of CYP2E1 protein	14631868
D014284	Triiodothyronine	Triiodothyronine results in increased expression of CYP2E1 protein	14631868
D013629	Tamoxifen	Tamoxifen results in decreased activity of CYP2E1 protein	18420780
D013654	Taurine	Taurine inhibits the reaction [Acetaminophen results in increased activity of CYP2E1 protein]	20166895
D013654	Taurine	Taurine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	20067817
D013654	Taurine	Taurine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]	20166895
C003377	taxifolin	taxifolin results in decreased expression of CYP2E1 mRNA	17541156
C489139	t-butyl acetylene	cumene hydroperoxide inhibits the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form]	15379534
C489139	t-butyl acetylene	cumene hydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein]	15379534
C489139	t-butyl acetylene	t-butyl acetylene results in decreased activity of CYP2E1 protein	15379534
C489139	t-butyl acetylene	t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form	15379534
C489139	t-butyl acetylene	tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein]	15379534
C489139	t-butyl acetylene	tert-Butylhydroperoxide promotes the reaction [t-butyl acetylene results in decreased activity of CYP2E1 protein mutant form]	15379534
D013662	Tea	Tea results in decreased expression of CYP2E1 mRNA	19370779
D013662	Tea	Tea results in decreased expression of CYP2E1 protein	19370779
D013662	Tea	Tea results in increased expression of and results in increased activity of CYP2E1 protein	24815822
C001803	tempol	tempol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
D000068698	Tenofovir	Tenofovir results in decreased activity of CYP2E1 protein	17162464
D013739	Testosterone	Testosterone results in increased expression of CYP2E1 mRNA	20403060
D013739	Testosterone	Testosterone results in increased expression of CYP2E1 protein	7839370
D013749	Tetrachlorodibenzodioxin	2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA]	28673560
D013749	Tetrachlorodibenzodioxin	AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA]	28673560
D013749	Tetrachlorodibenzodioxin	ARNT protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA]	28673560
D013749	Tetrachlorodibenzodioxin	[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP2E1 mRNA	26159488
D013749	Tetrachlorodibenzodioxin	Endosulfan promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA]	28673560
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA	22298810
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [Endosulfan results in decreased expression of CYP2E1 mRNA]	28673560
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP2E1	27055685
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA	20106945\|2129612
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 protein	28673560
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA	23669205
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP2E1 mRNA	17949056
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP2E1 gene]	28213091
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA	19770486\|2821309
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA	16120747
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of CYP2E1 mRNA	21602191
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP2E1 mRNA	16054898\|1879615
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP2E1 mRNA	19969063
D013750	Tetrachloroethylene	CYP2E1 protein results in increased susceptibility to Tetrachloroethylene	17433522
C009408	tetrachlorophenol	CYP2E1 protein results in increased oxidation of tetrachlorophenol	7747284
D013752	Tetracycline	bicyclol inhibits the reaction [Tetracycline results in decreased expression of CYP2E1 mRNA]	19427351
D013752	Tetracycline	Tetracycline results in decreased expression of CYP2E1 mRNA	19427351
D013755	Tetradecanoylphorbol Acetate	Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	9143349
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]	8531136
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136\|9143349
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol]	8798623
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein	8798623
D013793	Thallium	CYP2E1 results in increased susceptibility to Thallium	20549620
D013805	Theobromine	4-nitrophenol inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]	10215755
D013805	Theobromine	CYP2E1 protein results in increased chemical synthesis of Theobromine	1302044
D013805	Theobromine	CYP2E1 protein results in increased metabolism of Theobromine	10215755
D013805	Theobromine	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Theobromine]	10215755
D013806	Theophylline	CYP2E1 promoter SNP affects the hydroxylation of Theophylline	16841220
D013806	Theophylline	CYP2E1 protein affects the metabolism of Theophylline	15948934\|1684122
D013806	Theophylline	CYP2E1 protein results in increased chemical synthesis of Theophylline	1302044
D013806	Theophylline	CYP2E1 protein affects the metabolism of Theophylline	15985363
D013830	Thiadiazoles	Thiadiazoles analog results in decreased activity of CYP2E1 protein	9188722
D013844	Thiazoles	[Thiazoles co-treated with ciprofibrate] results in increased expression of CYP2E1 protein	7587954
D013853	Thioacetamide	CYP2E1 protein affects the reaction [Thioacetamide results in decreased expression of GPX1 mRNA]	18374380
D013853	Thioacetamide	CYP2E1 protein affects the reaction [Thioacetamide results in increased expression of IL6 mRNA]	18374380
D013853	Thioacetamide	CYP2E1 protein affects the reaction [Thioacetamide results in increased expression of NOS2 protein]	18374380
D013853	Thioacetamide	CYP2E1 protein affects the reaction [Thioacetamide results in increased expression of TNF mRNA]	18374380
D013853	Thioacetamide	CYP2E1 protein results in increased susceptibility to Thioacetamide	18374380
D013853	Thioacetamide	Thioacetamide results in decreased expression of CYP2E1 protein	27349771
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of CYP2E1 mRNA	28943392
D013853	Thioacetamide	Eugenol inhibits the reaction [Thioacetamide results in increased expression of CYP2E1 protein]	20036707
D013853	Thioacetamide	Thioacetamide results in decreased expression of CYP2E1 mRNA	16297948
D013853	Thioacetamide	Thioacetamide results in increased expression of CYP2E1 protein	20036707
D013875	Thiophanate	Thiophanate results in increased expression of CYP2E1 protein	10096430
D013881	Thioridazine	Thioridazine results in decreased activity of CYP2E1 protein	15135088
D013883	Thiostrepton	Thiostrepton results in decreased expression of CYP2E1 mRNA	22321511
D013893	Thiram	CYP2E1 protein results in increased metabolism of Thiram	12458634
D013893	Thiram	Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]	12458634
D008625	Tiopronin	Tiopronin inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein]	19683030
C049947	tirapazamine	1-phenylimidazole inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	2-Propanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	caffeic acid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	CAT protein inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	CYP2E1 protein results in increased reduction of and results in increased activity of and results in increased susceptibility to tirapazamine	7710944
C049947	tirapazamine	Deferoxamine inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	Dicumarol promotes the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	Ethanol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	Isoniazid inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	purpurogallin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	Quercetin inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C049947	tirapazamine	tempol inhibits the reaction [CYP2E1 protein results in increased reduction of tirapazamine]	7710944
C009495	titanium dioxide	titanium dioxide results in increased expression of CYP2E1 mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of CYP2E1 mRNA	23038017
D014050	Toluene	CYP2E1 protein affects the metabolism of Toluene	8592870
D014050	Toluene	Ditiocarb inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]	8592870
D014050	Toluene	fomepizole inhibits the reaction [CYP2E1 protein affects the metabolism of Toluene]	8592870
D014050	Toluene	CYP2E1 gene polymorphism affects the susceptibility to Toluene	17292523
D014050	Toluene	CYP2E1 protein alternative form results in increased metabolism of Toluene	20033806
D014050	Toluene	CYP2E1 protein results in increased metabolism of Toluene	12464242\|1835091
D014050	Toluene	Ditiocarb inhibits the reaction [CYP2E1 protein results in increased metabolism of Toluene]	8558417
D014050	Toluene	Smoke affects the reaction [Toluene affects the methylation of CYP2E1 promoter]	25963742
D014050	Toluene	Toluene affects the activity of CYP2E1 protein	25963742
D014050	Toluene	Toluene affects the methylation of CYP2E1 promoter	25963742
D014050	Toluene	Toluene results in increased expression of CYP2E1 mRNA	16581535\|2596374
D014050	Toluene	CYP2E1 protein results in increased metabolism of Toluene	8461037
D014050	Toluene	[Toluene co-treated with Benzene] results in increased activity of CYP2E1 protein	18455711
D014050	Toluene	Acetone promotes the reaction [Toluene results in increased expression of CYP2E1 protein]	8996725
D014050	Toluene	[Benzene results in increased expression of CYP2E1 protein] which results in increased metabolism of Toluene	9010585
D014050	Toluene	CYP2E1 protein affects the metabolism of Toluene	8620572
D014050	Toluene	CYP2E1 protein affects the reaction [Benzene results in increased metabolism of Toluene]	8620572
D014050	Toluene	CYP2E1 protein affects the reaction [Toluene results in increased metabolism of Toluene]	8620572
D014050	Toluene	CYP2E1 protein affects the reaction [Trichloroethylene results in increased metabolism of Toluene]	8620572
D014050	Toluene	CYP2E1 protein results in increased metabolism of Toluene	8461037
D014050	Toluene	CYP2E1 protein results in increased oxidation of Toluene	1994898
D014050	Toluene	Ethanol promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene]	1994898
D014050	Toluene	Methylcholanthrene promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene]	1994898
D014050	Toluene	Toluene promotes the reaction [CYP2E1 protein results in increased metabolism of Methylene Chloride]	8889796
D014050	Toluene	Toluene results in increased activity of CYP2E1 protein	12919724\|8620572
D014050	Toluene	Toluene results in increased expression of CYP2E1 mRNA	12919724
D014050	Toluene	Toluene results in increased expression of CYP2E1 protein	12919724\|8517779
D014050	Toluene	Disulfiram inhibits the reaction [Toluene results in increased activity of CYP2E1 protein]	12781212
D014050	Toluene	Toluene results in increased activity of CYP2E1 protein	12781212
D014107	Tosyllysine Chloromethyl Ketone	Tosyllysine Chloromethyl Ketone inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein]	9143349
C099150	trabectedin	trabectedin results in decreased activity of CYP2E1 protein	12154027
C507866	trans-1,2-dihydro-1,2-naphthalenediol	"CYP2E1 protein results in increased abundance of trans-1,2-dihydro-1,2-naphthalenediol"	16243959
C560613	transfluthrin	transfluthrin results in increased expression of and results in increased activity of CYP2E1 protein	22080754
D014191	Tranylcypromine	Tranylcypromine results in decreased activity of CYP2E1 protein	15155557
D014212	Tretinoin	Tretinoin promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]	8531136
D014212	Tretinoin	Tretinoin results in increased expression of CYP2E1 mRNA	24977338
D014212	Tretinoin	CYP2E1 protein results in increased metabolism of Tretinoin	16054987
D014212	Tretinoin	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Tretinoin]	16054987
C032910	triadimefon	triadimefon results in decreased expression of CYP2E1 mRNA	16730040
C447082	tricarbonyldichlororuthenium (II) dimer	tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	19325051
C447082	tricarbonyldichlororuthenium (II) dimer	zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]]	19325051
D014241	Trichloroethylene	CYP2E1 gene polymorphism results in increased susceptibility to Trichloroethylene	19351467
D014241	Trichloroethylene	CYP2E1 protein affects the metabolism of Trichloroethylene	17710613
D014241	Trichloroethylene	CYP2E1 protein results in increased metabolism of Trichloroethylene	10841534\|1835091
D014241	Trichloroethylene	CYP2E1 protein results in increased oxidation of Trichloroethylene	1664256
D014241	Trichloroethylene	Trichloroethylene results in increased activity of CYP2E1 protein	17710613
D014241	Trichloroethylene	CYP2E1 protein results in increased metabolism of Trichloroethylene	10774820\|1856556
D014241	Trichloroethylene	[diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene	10774820
D014241	Trichloroethylene	Trichloroethylene results in increased expression of CYP2E1 protein	10753203
D014241	Trichloroethylene	"1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Trichloroethylene]"	7871537
D014241	Trichloroethylene	CYP2E1 protein affects the metabolism of Trichloroethylene	17710613\|7871537
D014241	Trichloroethylene	CYP2E1 protein affects the reaction [Trichloroethylene results in increased metabolism of Toluene]	8620572
D014241	Trichloroethylene	CYP2E1 protein results in increased metabolism of Trichloroethylene	1739413\|18249509
D014241	Trichloroethylene	[CYP2E1 protein results in increased metabolism of Trichloroethylene] which results in increased chemical synthesis of Chloral Hydrate	1739413
D014241	Trichloroethylene	CYP2E1 protein results in increased susceptibility to Trichloroethylene	17433522
D014241	Trichloroethylene	Trichloroethylene inhibits the reaction [Acetone results in increased activity of CYP2E1 protein]	9851676
D014241	Trichloroethylene	Trichloroethylene results in increased activity of CYP2E1 protein	17710613\|8620572
D014241	Trichloroethylene	Trichloroethylene results in increased expression of CYP2E1 protein	8620572
C025280	trichloromethyl free radical	[CYP2E1 protein results in increased metabolism of Carbon Tetrachloride] which results in increased abundance of trichloromethyl free radical	19336974
D022882	Trihalomethanes	CYP2E1 gene SNP results in increased susceptibility to Trihalomethanes	15289170
D022882	Trihalomethanes	CYP2E1 polymorphism affects the susceptibility to Trihalomethanes	20675267
D022882	Trihalomethanes	CYP2E1 protein results in increased metabolism of Trihalomethanes	24647036
D014302	Trinitrobenzenesulfonic Acid	Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2E1 protein	18079364
C057693	troglitazone	troglitazone results in increased expression of CYP2E1 mRNA	28973697
C057693	troglitazone	troglitazone results in increased expression of CYP2E1 mRNA	21515302
D014363	Tryptamines	Tryptamines analog results in decreased activity of CYP2E1 protein	26599973
D014363	Tryptamines	[Tryptamines analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone	26599973
C012596	turmeric extract	turmeric extract affects the reaction [Cisplatin results in decreased activity of CYP2E1 protein]	24882083
C012596	turmeric extract	turmeric extract affects the reaction [Paclitaxel results in decreased activity of CYP2E1 protein]	24882083
C113580	U 0126	U 0126 inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]	28385499
C113580	U 0126	U 0126 inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	28385499
D014501	Uranium	[Acetaminophen co-treated with Uranium analog] results in decreased expression of CYP2E1 mRNA	17126469
D014501	Uranium	Uranium analog promotes the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]	17126469
D014520	Urethane	CYP2E1 protein results in increased oxidation of Urethane	1664256
D014520	Urethane	1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane]	12704224
D014520	Urethane	CYP2E1 gene mutant form inhibits the reaction [Urethane affects the expression of MKI67 protein]	15790490
D014520	Urethane	CYP2E1 gene mutant form results in decreased metabolism of Urethane	12704224
D014520	Urethane	CYP2E1 gene mutant form results in decreased susceptibility to Urethane	17093202
D014520	Urethane	CYP2E1 protein affects the hydroxylation of Urethane	15879495
D014520	Urethane	CYP2E1 protein affects the metabolism of Urethane	12704224\|1587949
D014520	Urethane	CYP2E1 protein affects the oxidation of Urethane	20205516
D014520	Urethane	CYP2E1 protein results in increased susceptibility to Urethane	15790490
D014520	Urethane	[Urethane co-treated with Ethanol] results in increased activity of CYP2E1 protein	15582191
D014520	Urethane	CYP2E1 affects the oxidation of Urethane	17341656
D014520	Urethane	CYP2E1 protein affects the oxidation of Urethane	17093202
D014580	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of and results in decreased activity of CYP2E1 protein]	10453939
C073339	usnic acid	[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP2E1 mRNA	22777745
C073339	usnic acid	usnic acid results in decreased expression of CYP2E1 mRNA	21953288\|2277774
D014635	Valproic Acid	Valproic Acid results in decreased expression of CYP2E1 mRNA	29154799
D014635	Valproic Acid	Valproic Acid results in decreased expression of CYP2E1 mRNA	17381134
C043425	vanoxerine	[Chlorzoxazone results in decreased activity of CYP2E1 protein] which results in decreased degradation of vanoxerine	11502731
C043425	vanoxerine	CYP2E1 protein results in decreased degradation of vanoxerine	11502731
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of CYP2E1 mRNA	22352393\|2421647
C025643	vinclozolin	[acephate co-treated with vinclozolin] affects the expression of CYP2E1 protein	17686559
C025643	vinclozolin	[fenarimol co-treated with vinclozolin] affects the expression of CYP2E1 protein	17686559
C025643	vinclozolin	[fenarimol co-treated with vinclozolin co-treated with acephate] affects the expression of CYP2E1 protein	17686559
C025643	vinclozolin	vinclozolin affects the expression of CYP2E1 mRNA	8921505
C025643	vinclozolin	vinclozolin affects the expression of CYP2E1 protein	8921505
C025643	vinclozolin	vinclozolin results in increased expression of CYP2E1 protein	25929820
C003763	vinyl bromide	CYP2E1 protein results in increased oxidation of vinyl bromide	1664256
C017963	vinyl carbamate	CYP2E1 protein affects the metabolism of vinyl carbamate	11181492
C017963	vinyl carbamate	CYP2E1 protein results in increased oxidation of vinyl carbamate	1664256
C017963	vinyl carbamate	[vinyl carbamate co-treated with NADP] inhibits the reaction [CYP2E1 protein results in decreased methylation of Dimethylnitrosamine]	11181492
C017963	vinyl carbamate	CYP2E1 protein affects the metabolism of vinyl carbamate	11181492
C017963	vinyl carbamate	CYP2E1 protein affects the oxidation of vinyl carbamate	20205516
C017963	vinyl carbamate	diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate]	17341656
C017963	vinyl carbamate	[diallyl sulfone results in decreased activity of CYP2E1 protein] which affects the susceptibility to vinyl carbamate	20205516
C017963	vinyl carbamate	vinyl carbamate results in decreased activity of CYP2E1 protein	11134547
C017963	vinyl carbamate	vinyl carbamate results in decreased expression of CYP2E1 protein	11134547
C017963	vinyl carbamate	CYP2E1 protein affects the oxidation of vinyl carbamate	17296623
C017963	vinyl carbamate	diallyl sulfone inhibits the reaction [CYP2E1 protein affects the oxidation of vinyl carbamate]	17296623
C017963	vinyl carbamate	CYP2E1 affects the oxidation of vinyl carbamate	17341656
D014752	Vinyl Chloride	CYP2E1 gene polymorphism affects the susceptibility to Vinyl Chloride	20134343
D014752	Vinyl Chloride	CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of KRAS gene]	12705718
D014752	Vinyl Chloride	CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]	12705718
D014752	Vinyl Chloride	CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of KRAS gene]	17384900
D014752	Vinyl Chloride	CYP2E1 gene polymorphism promotes the reaction [Vinyl Chloride results in increased mutagenesis of TP53 gene]	12010862\|1738490
D014752	Vinyl Chloride	CYP2E1 gene polymorphism results in increased susceptibility to Vinyl Chloride	16270392
D014752	Vinyl Chloride	CYP2E1 gene SNP results in increased susceptibility to Vinyl Chloride	18420361\|2010073
D014752	Vinyl Chloride	CYP2E1 protein affects the metabolism of Vinyl Chloride	17710613
D014752	Vinyl Chloride	CYP2E1 protein results in increased metabolism of Vinyl Chloride	18350910
D014752	Vinyl Chloride	CYP2E1 protein results in increased oxidation of Vinyl Chloride	1664256
D014752	Vinyl Chloride	Vinyl Chloride results in increased activity of CYP2E1 protein	17710613
D014752	Vinyl Chloride	"1,2-dichloroethylene inhibits the reaction [CYP2E1 protein affects the metabolism of Vinyl Chloride]"	7871537
D014752	Vinyl Chloride	CYP2E1 protein affects the metabolism of Vinyl Chloride	17710613\|7871537
D014752	Vinyl Chloride	Vinyl Chloride results in increased activity of CYP2E1 protein	15211785\|1771061
D014752	Vinyl Chloride	CYP2E1 protein affects the metabolism of Vinyl Chloride	18420361
D014752	Vinyl Chloride	CYP2E1 protein results in increased metabolism of Vinyl Chloride	26962056
D014752	Vinyl Chloride	[CYP2E1 protein results in increased metabolism of Vinyl Chloride] which results in increased abundance of Ethylene Chlorohydrin	26962056
C016829	vinyl fluoride	[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased metabolism of vinyl fluoride	9073601
C016829	vinyl fluoride	CYP2E1 protein affects the oxidation of vinyl fluoride	9073601
C016829	vinyl fluoride	[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride	9073601
C016829	vinyl fluoride	[Ethanol results in increased activity of CYP2E1 protein] which results in increased metabolism of vinyl fluoride	9073601
C016829	vinyl fluoride	[fomepizole results in decreased activity of CYP2E1 protein] which results in decreased uptake of vinyl fluoride	9073601
C029297	vinylidene chloride	CYP2E1 protein results in increased metabolism of vinylidene chloride	10215634\|1531934
C029297	vinylidene chloride	diallyl sulfone inhibits the reaction [CYP2E1 protein results in increased metabolism of vinylidene chloride]	10215634
C029297	vinylidene chloride	CYP2E1 protein results in increased metabolism of vinylidene chloride	11356946\|1531934
C029297	vinylidene chloride	vinylidene chloride results in increased expression of CYP2E1 protein	26682919
C029297	vinylidene chloride	CYP2E1 protein results in increased metabolism of vinylidene chloride	15319346
D014800	Vitallium	Vitallium analog results in decreased expression of CYP2E1 mRNA	23825117
D014801	Vitamin A	CYP2E1 protein results in increased metabolism of Vitamin A	16054987
D014801	Vitamin A	Ethanol promotes the reaction [CYP2E1 protein results in increased metabolism of Vitamin A]	16054987
D013831	Thiamine	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D013831	Thiamine	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D009536	Niacinamide	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D009536	Niacinamide	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
D014805	Vitamin B 12	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
D014810	Vitamin E	Vitamin E inhibits the reaction [CYP2E1 protein results in increased expression of COL1A2 mRNA]	10498651
D014810	Vitamin E	Vitamin E inhibits the reaction [decamethrin results in increased expression of CYP2E1 mRNA]	25439240
D024483	Vitamin K 3	Vitamin K 3 results in decreased expression of CYP2E1 mRNA	25270620
C574123	walrycin A	walrycin A results in increased expression of CYP2E1 mRNA	22314385
C009687	wortmannin	wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA]	11306697
C581157	XL147	[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of CYP2E1 mRNA	27935865
C098009	YH 439	YH 439 inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of CYP2E1 protein]	11562448
C098009	YH 439	YH 439 results in decreased expression of and results in decreased activity of CYP2E1 protein	11562448
C098009	YH 439	YH 439 results in decreased expression of CYP2E1 mRNA	11562448
D015032	Zinc	[Zinc deficiency co-treated with Ethanol] results in increased expression of CYP2E1 protein	24155903
D015032	Zinc	Zinc deficiency results in increased expression of CYP2E1 protein	24155903
D015032	Zinc	[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]	21424224
D015032	Zinc	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]	27919644
D015032	Zinc	[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]	27919644
C017803	zinc protoporphyrin	zinc protoporphyrin inhibits the reaction [Quercetin inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]]	19325051
C017803	zinc protoporphyrin	zinc protoporphyrin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]]	19325051
C017803	zinc protoporphyrin	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 mRNA	26747958
C017803	zinc protoporphyrin	[[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] co-treated with zinc protoporphyrin] results in increased expression of CYP2E1 protein	26747958
C017803	zinc protoporphyrin	zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 mRNA]	26747958
C017803	zinc protoporphyrin	zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased expression of CYP2E1 protein]	26747958
D019287	Zinc Sulfate	CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate]	12566070
D019287	Zinc Sulfate	Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Arachidonic Acid]	12566070
D019287	Zinc Sulfate	Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Buthionine Sulfoximine]	12566070
D019287	Zinc Sulfate	[Betaine co-treated with Choline co-treated with Folic Acid co-treated with Methionine co-treated with Vitamin B 12 co-treated with Zinc Sulfate] inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	20118189
D019287	Zinc Sulfate	Zinc Sulfate inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	15920153
D019287	Zinc Sulfate	Zinc Sulfate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]	15920153
D019287	Zinc Sulfate	Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA]	20553223
D019287	Zinc Sulfate	Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA]	20553223
D019287	Zinc Sulfate	Zinc Sulfate results in increased expression of CYP2E1 mRNA	20553223
C013738	zingerone	zingerone inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein]	28442378
D015049	Zoxazolamine	CYP2E1 protein results in increased metabolism of and results in decreased activity of Zoxazolamine	16109766

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004497	monooxygenase activity	-	IDA	19651758
GO:0004497	monooxygenase activity	-	TAS	-
GO:0005506	iron ion binding	-	IEA	-
GO:0008392	arachidonic acid epoxygenase activity	-	IBA	21873635
GO:0008395	steroid hydroxylase activity	-	IBA	21873635
GO:0016491	oxidoreductase activity	-	IDA	16401082 19219744
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	-	TAS	18818195
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	-	IBA	21873635
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	-	IEA	-
GO:0019825	oxygen binding	-	TAS	3233219
GO:0019899	enzyme binding	-	IPI	15680923
GO:0020037	heme binding	-	IBA	21873635
GO:0020037	heme binding	-	IDA	18818195

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006082	organic acid metabolic process	-	IBA	21873635
GO:0006641	triglyceride metabolic process	-	IEA	-
GO:0006805	xenobiotic metabolic process	-	IBA	21873635
GO:0006805	xenobiotic metabolic process	-	TAS	-
GO:0008202	steroid metabolic process	-	IMP	18356043
GO:0010193	response to ozone	-	IEA	-
GO:0010243	response to organonitrogen compound	-	IEA	-
GO:0016098	monoterpenoid metabolic process	-	IDA	16401082
GO:0017144	drug metabolic process	-	IDA	19219744
GO:0017144	drug metabolic process	-	IMP	18356043
GO:0017144	drug metabolic process	-	TAS	-
GO:0018885	carbon tetrachloride metabolic process	-	TAS	-
GO:0018910	benzene metabolic process	-	TAS	-
GO:0042197	halogenated hydrocarbon metabolic process	-	TAS	-
GO:0042738	exogenous drug catabolic process	-	IBA	21873635
GO:0042759	long-chain fatty acid biosynthetic process	-	TAS	-
GO:0045471	response to ethanol	-	IEA	-
GO:0046483	heterocycle metabolic process	-	IDA	19651758
GO:0055114	oxidation-reduction process	-	IBA	21873635
GO:0055114	oxidation-reduction process	-	IDA	16401082 19219744

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0000139	Golgi membrane	-	IEA	-
GO:0005737	cytoplasm	-	IBA	21873635
GO:0005739	mitochondrion	-	IEA	-
GO:0005789	endoplasmic reticulum membrane	-	TAS	-
GO:0031227	intrinsic component of endoplasmic reticulum membrane	-	IEA	-
GO:0043231	intracellular membrane-bounded organelle	-	IBA	21873635

KEGG ID	KEGG Term
hsa00590	Arachidonic acid metabolism
hsa00591	Linoleic acid metabolism
hsa00980	Metabolism of xenobiotics by cytochrome P450
hsa00982	Drug metabolism - cytochrome P450
hsa01100	Metabolic pathways

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-211859	Biological oxidations	TAS
R-HSA-211897	Cytochrome P450 - arranged by substrate type	TAS
R-HSA-211945	Phase I - Functionalization of compounds	TAS
R-HSA-211981	Xenobiotics	TAS
R-HSA-211999	CYP2E1 reactions	TAS
R-HSA-556833	Metabolism of lipids	TAS
R-HSA-8978868	Fatty acid metabolism	TAS
R-HSA-9018677	Biosynthesis of DHA-derived SPMs	TAS
R-HSA-9018678	Biosynthesis of specialized proresolving mediators (SPMs)	TAS
R-HSA-9018682	Biosynthesis of maresins	TAS
R-HSA-9027307	Biosynthesis of maresin-like SPMs	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
9456237	Cytochrome P450 2E1 DraI polymorphisms in lung cancer in minority populations. (1998 Jan)	Wu X	Cancer Epidemiol Biomarkers Prev
12376511	Influence of metabolic genotypes on biomarkers of exposure to 1,3-butadiene in humans. (2002 Oct)	Fustinoni S	Cancer Epidemiol Biomarkers Prev
27284439	Association between CYP2E1 polymorphisms and risk of gastric cancer: An updated meta-analysis of 32 case-control studies. (2016 Jun)	Zhang MX	Mol Clin Oncol
17885617	Genetic polymorphisms and benzene metabolism in humans exposed to a wide range of air concentrations. (2007 Oct)	Kim S	Pharmacogenet Genomics
21833537	Chronic alcohol intake-induced oxidative stress and apoptosis: role of CYP2E1 and calpain-1 in alcoholic cardiomyopathy. (2012 Jan)	Jing L	Mol Cell Biochem
16425414	Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease. (2005 Nov 7)	Cartmell MT	World J Gastroenterol
14586387	Effects of cigarette smoking and carbon monoxide on chlorzoxazone and caffeine metabolism. (2003 Nov)	Benowitz NL	Clin Pharmacol Ther
12901271	[Alcoholic liver disease]. (2003)	Waluga M	Wiad Lek
29116991	Association Between Polymorphisms of Metabolic Enzyme Genes and Chromosomal Damage in Benzene-Exposed Workers in China. (2017 Nov)	Fang Y	J Occup Environ Med
11911601	Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients in a department of surgical medicine--a pilot investigation. (2002 Mar)	Farker K	Int J Clin Pharmacol Ther
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