| C495657 | 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane | "CYP3A5 protein results in increased hydroxylation of 1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane" | 12167570 |
| C090768 | 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene | "CYP3A5 protein results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene" | 29285606 |
| C090768 | 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene | "CYP3A5 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene" | 29285606 |
| C090768 | 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene | "[CYP3A5 protein results in increased metabolism of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene metabolite" | 29285606 |
| C090768 | 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene | "[CYP3A5 protein results in increased metabolism of N-desmethyltamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene" | 29285606 |
| C090768 | 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene | "[CYP3A5 protein results in increased metabolism of Tamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene" | 29285606 |
| C035342 | 1,4-naphthoquinone | "CYP3A5 protein results in increased abundance of 1,4-naphthoquinone" | 16243959 |
| C486136 | 16-O-demethylaconitine | [CYP3A5 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine | 21277363 |
| C033020 | 1-aminobenzotriazole | 1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| C040081 | 1-hydroxymethylmidazolam | CYP3A5 protein results in increased chemical synthesis of 1-hydroxymethylmidazolam | 18191104|2695886 |
| C029350 | 1-naphthol | CYP3A5 protein results in increased abundance of 1-naphthol | 16243959 |
| C120227 | 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide | "2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased expression of CYP3A5 mRNA" | 24819614 |
| C586542 | 2'-(glutathion-S-yl)-deschlorodiclofenac | [CYP3A5 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac | 24246759 |
| C041477 | 3-hydroxyflavone | 3-hydroxyflavone results in increased expression of CYP3A5 mRNA | 26238175 |
| C028657 | 3-methoxymorphinan | CYP3A5 protein affects the chemical synthesis of 3-methoxymorphinan | 15988119 |
| C042940 | 4-hydroxymidazolam | CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam | 18191104 |
| C042940 | 4-hydroxymidazolam | diosmetin inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam] | 18191104 |
| C042940 | 4-hydroxymidazolam | Luteolin inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam] | 18191104 |
| C055492 | 4-hydroxy-N-desmethyltamoxifen | CYP3A5 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen | 29285606 |
| C055492 | 4-hydroxy-N-desmethyltamoxifen | [CYP3A5 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen] which results in increased abundance of 4-hydroxy-N-desmethyltamoxifen metabolite | 29285606 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | CYP3A5 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 25221795 |
| C117715 | 5-hydroxydiclofenac | [CYP3A5 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac | 24246759 |
| C544471 | 5-hydroxythalidomide | [CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide | 20443640 |
| C544471 | 5-hydroxythalidomide | CYP3A5 protein results in increased oxidation of and results in increased glutathionylation of 5-hydroxythalidomide | 20443640 |
| C544471 | 5-hydroxythalidomide | [CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide | 20443640 |
| C025591 | 6 beta-hydroxytestosterone | CYP3A5 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone | 26239802 |
| C025591 | 6 beta-hydroxytestosterone | Meclizine inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone] | 26239802 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of CYP3A5 mRNA | 29067470 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of CYP3A5 mRNA | 26497421 |
| D000157 | Aconitine | CYP3A5 protein results in increased metabolism of Aconitine | 21277363 |
| D000157 | Aconitine | [CYP3A5 protein results in increased metabolism of Aconitine] which results in increased chemical synthesis of 16-O-demethylaconitine | 21277363 |
| C016601 | afimoxifene | afimoxifene results in decreased activity of CYP3A5 protein | 12419016 |
| C016601 | afimoxifene | CYP3A5 protein results in increased metabolism of afimoxifene | 29285606 |
| C016601 | afimoxifene | [CYP3A5 protein results in increased metabolism of afimoxifene] which results in increased abundance of afimoxifene metabolite | 29285606 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of CYP3A5 protein | 20106945 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased expression of CYP3A5 mRNA | 22100608|2715375 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of CYP3A5 mRNA | 21632981|2199423 |
| D016604 | Aflatoxin B1 | CYP3A5 protein results in increased activity of Aflatoxin B1 | 15454734 |
| C027955 | aflatoxin G1 | CYP3A5 protein results in increased susceptibility to aflatoxin G1 | 11189750 |
| D015760 | Alfentanil | CYB5A protein promotes the reaction [CYP3A5 protein affects the metabolism of Alfentanil] | 15557344 |
| D015760 | Alfentanil | CYP3A5 protein affects the metabolism of Alfentanil | 15557344|1573159 |
| D015760 | Alfentanil | Ketoconazole inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil] | 15731592 |
| D015760 | Alfentanil | Troleandomycin inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil] | 15731592 |
| D000525 | Alprazolam | CYP3A5 protein results in increased hydroxylation of Alprazolam | 15903124 |
| D000638 | Amiodarone | CYP3A5 protein results in decreased susceptibility to Amiodarone | 26477383 |
| D000639 | Amitriptyline | Amitriptyline results in increased metabolism of CYP3A5 protein | 18359012 |
| D017311 | Amlodipine | CYP3A5 gene affects the susceptibility to Amlodipine | 22149319 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in increased expression of CYP3A5 mRNA | 24449571 |
| D001507 | Beclomethasone | 1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D001507 | Beclomethasone | Beclomethasone results in increased expression of CYP3A5 mRNA | 12538830|2351253 |
| D001507 | Beclomethasone | Ketoconazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D001507 | Beclomethasone | Mifepristone inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 12538830 |
| D001507 | Beclomethasone | Paraoxon inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D001507 | Beclomethasone | Physostigmine inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D001507 | Beclomethasone | CYP3A5 protein results in increased metabolism of Beclomethasone | 23512537 |
| C065857 | beclomethasone 17-monopropionate | beclomethasone 17-monopropionate results in increased expression of CYP3A5 mRNA | 24555085 |
| C065857 | beclomethasone 17-monopropionate | NR3C1 mRNA promotes the reaction [beclomethasone 17-monopropionate results in increased expression of CYP3A5 mRNA] | 24555085 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CYP3A5 mRNA | 20106945|2163298 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CYP3A5 mRNA" | 20018196 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CYP3A5 mRNA" | 19150397 |
| C006780 | bisphenol A | CYP3A5 protein results in increased metabolism of bisphenol A | 21402134 |
| C006780 | bisphenol A | [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone | 21402134 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of CYP3A5 mRNA | 25181051 |
| D015124 | 8-Bromo Cyclic Adenosine Monophosphate | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CYP3A5 mRNA | 22079614 |
| D019819 | Budesonide | Budesonide results in increased expression of CYP3A5 mRNA | 12538830|2455508 |
| D019819 | Budesonide | Ketoconazole inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA] | 24555085 |
| D019819 | Budesonide | Mifepristone inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA] | 12538830 |
| D002065 | Buspirone | CYP3A5 protein results in increased oxidation of Buspirone | 15640381 |
| D002185 | Cannabidiol | Cannabidiol results in decreased activity of CYP3A5 protein | 24667653 |
| D002220 | Carbamazepine | Carbamazepine results in increased expression of CYP3A5 mRNA | 12673034 |
| C035038 | carbosulfan | CYP3A5 protein results in increased metabolism of carbosulfan | 20307514 |
| D002330 | Carmustine | CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] | 16087946 |
| C088453 | Celsior | Celsior results in decreased expression of CYP3A5 mRNA | 15448115 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in increased expression of CYP3A5 mRNA | 17851650 |
| D002746 | Chlorpromazine | CYP3A5 protein results in decreased susceptibility to Chlorpromazine | 26477383 |
| D004390 | Chlorpyrifos | Chlorpyrifos results in increased expression of CYP3A5 mRNA | 16757081 |
| D004390 | Chlorpyrifos | CYP3A5 protein affects the metabolism of Chlorpyrifos | 17079358|1711006 |
| D002990 | Clobetasol | Clobetasol results in increased expression of CYP3A5 mRNA | 16882163 |
| C055162 | clopidogrel | CYP3A5 gene polymorphism affects the susceptibility to clopidogrel | 16754899 |
| C055162 | clopidogrel | CYP3A5 protein results in increased oxidation of and results in increased cleavage of clopidogrel metabolite | 19170597 |
| D003022 | Clotrimazole | Clotrimazole results in increased expression of CYP3A5 protein | 8632764 |
| D003024 | Clozapine | CYP3A5 protein results in increased metabolism of Clozapine | 18809730 |
| C079149 | clozapine N-oxide | CYP3A5 protein results in increased chemical synthesis of clozapine N-oxide | 18809730 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of CYP3A5 mRNA | 22941251 |
| D019327 | Copper Sulfate | Copper Sulfate results in increased expression of CYP3A5 mRNA | 19549813 |
| D003345 | Corticosterone | Corticosterone results in increased metabolism of CYP3A5 protein | 20032461 |
| C059483 | CQA 206-291 | CYP3A5 protein results in increased metabolism of CQA 206-291 | 1346997 |
| D003520 | Cyclophosphamide | CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] | 16087946 |
| D003520 | Cyclophosphamide | CYP3A5 gene polymorphism affects the susceptibility to Cyclophosphamide | 16087946 |
| D003520 | Cyclophosphamide | CYP3A5 protein affects the metabolism of Cyclophosphamide | 16087946 |
| D003520 | Cyclophosphamide | CYP3A5 results in increased activity of Cyclophosphamide | 8717162 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of CYP3A5 mRNA | 20106945|2556210 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of CYP3A5 mRNA | 12673034 |
| D016572 | Cyclosporine | CYP3A5 protein affects the metabolism of Cyclosporine | 15450954|1545473 |
| D016572 | Cyclosporine | CYP3A5 protein polymorphism affects the metabolism of Cyclosporine | 15808586 |
| D003609 | Dactinomycin | Dactinomycin inhibits the reaction [U 0126 results in increased expression of CYP3A5 mRNA] | 24819614 |
| C010902 | decabromobiphenyl ether | decabromobiphenyl ether analog results in increased expression of CYP3A5 mRNA | 25222814 |
| C064445 | dechloroethylcyclophosphamide | CYP3A5 protein affects the chemical synthesis of dechloroethylcyclophosphamide | 15875221 |
| C014347 | decitabine | decitabine inhibits the reaction [Smoke results in decreased expression of CYP3A5 mRNA] | 21095227 |
| D003671 | DEET | CYP3A5 protein results in increased metabolism of DEET | 11854147 |
| D003671 | DEET | DEET results in increased expression of CYP3A5 mRNA | 27091632 |
| D003671 | DEET | [fipronil co-treated with DEET] results in increased expression of CYP3A5 mRNA | 27091632 |
| D003687 | Dehydroepiandrosterone | CYP3A5 protein results in increased hydroxylation of Dehydroepiandrosterone | 15845858 |
| D003907 | Dexamethasone | Dexamethasone results in increased expression of CYP3A5 mRNA | 10696073|1253883 |
| D003907 | Dexamethasone | Mifepristone inhibits the reaction [Dexamethasone results in increased expression of CYP3A5 mRNA] | 12538830 |
| D003907 | Dexamethasone | NR3C1 protein affects the reaction [Dexamethasone results in increased expression of CYP3A5 mRNA] | 12538830 |
| D003917 | Dextrorphan | CYP3A5 protein affects the metabolism of Dextrorphan | 15988119 |
| D003976 | Diazinon | Diazinon results in increased expression of CYP3A5 mRNA | 16757081 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in increased expression of CYP3A5 mRNA | 27392435 |
| D002945 | Cisplatin | CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] | 16087946 |
| C000944 | dicrotophos | dicrotophos results in decreased expression of CYP3A5 mRNA | 28302478 |
| D002117 | Calcitriol | Calcitriol results in increased expression of CYP3A5 mRNA | 16002434|2159239 |
| D002117 | Calcitriol | [Testosterone co-treated with Calcitriol] results in increased expression of CYP3A5 mRNA | 21592394 |
| D004110 | Diltiazem | CYP3A5 protein affects the metabolism of Diltiazem | 16024008 |
| D004110 | Diltiazem | CYP3A5 protein polymorphism affects the metabolism of Diltiazem | 16024008 |
| D004110 | Diltiazem | CYP3A5 protein results in decreased methylation of Diltiazem | 15499178 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide affects the expression of CYP3A5 mRNA | 12843640 |
| C039602 | diosmetin | diosmetin inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam] | 18191104 |
| C038345 | droloxifene | droloxifene results in decreased activity of CYP3A5 protein | 12419016 |
| D004726 | Endosulfan | CYP3A5 protein affects the metabolism of Endosulfan | 16581944 |
| D004917 | Erythromycin | CYP3A5 protein results in decreased methylation of Erythromycin | 15383492 |
| D004997 | Ethinyl Estradiol | CYP3A5 protein results in increased hydroxylation of Ethinyl Estradiol | 15304426 |
| D005047 | Etoposide | CYP3A5 gene polymorphism affects the susceptibility to Etoposide | 12969965 |
| D005047 | Etoposide | CYP3A5 protein results in decreased methylation of Etoposide | 8114683 |
| C010087 | eucalyptol | CYP3A5 protein results in increased hydroxylation of eucalyptol | 15715982 |
| D005284 | Fenthion | CYP3A5 protein affects the metabolism of Fenthion | 17110060 |
| C082360 | fipronil | [fipronil co-treated with DEET] results in increased expression of CYP3A5 mRNA | 27091632 |
| C082360 | fipronil | fipronil results in increased expression of CYP3A5 mRNA | 17084830|2709163 |
| C007734 | flunisolide | flunisolide results in increased expression of CYP3A5 mRNA | 24555085 |
| C007734 | flunisolide | Ketoconazole inhibits the reaction [flunisolide results in increased expression of CYP3A5 mRNA] | 24555085 |
| D005445 | Flunitrazepam | CYP3A5 protein results in increased hydroxylation of Flunitrazepam | 15383492 |
| D005473 | Fluoxetine | Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D000068298 | Fluticasone | CYP3A5 protein affects the susceptibility to Fluticasone | 20707410 |
| D000068298 | Fluticasone | CYP3A5 protein results in increased metabolism of Fluticasone | 20707410 |
| D000068298 | Fluticasone | Fluticasone results in decreased activity of CYP3A5 protein | 20707410 |
| D000068298 | Fluticasone | Fluticasone results in increased expression of CYP3A5 mRNA | 24555085 |
| D000068298 | Fluticasone | Ketoconazole inhibits the reaction [Fluticasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D016666 | Fluvoxamine | Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| C009252 | fructus schizandrae, radix ginseng, radix ophiopogonis drug combination | "fructus schizandrae, radix ginseng, radix ophiopogonis drug combination affects the reaction [CYP3A5 protein affects the metabolism of Midazolam]" | 19557931 |
| C419708 | gefitinib | CYP3A5 protein affects the metabolism of gefitinib | 15788367 |
| D005938 | Glucocorticoids | CYP3A5 protein results in increased metabolism of Glucocorticoids | 24555085 |
| D005938 | Glucocorticoids | [[Glucocorticoids binds to NR3C1 protein] which results in increased expression of NR1I2] which results in increased expression of CYP3A5 | 24555085 |
| D005938 | Glucocorticoids | [[Glucocorticoids binds to NR3C1 protein] which results in increased expression of NR1I3] which results in increased expression of CYP3A5 | 24555085 |
| D005978 | Glutathione | [CYP3A5 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 2'-(glutathion-S-yl)-deschlorodiclofenac | 24246759 |
| D005978 | Glutathione | [CYP3A5 protein co-treated with GSTP1 protein co-treated with Glutathione] results in increased abundance of 5-hydroxydiclofenac | 24246759 |
| D005978 | Glutathione | CYP3A5 protein promotes the reaction [tetrandrine results in decreased abundance of Glutathione] | 26302866 |
| D006220 | Haloperidol | CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol | 12584149 |
| D006220 | Haloperidol | Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D006220 | Haloperidol | Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D006220 | Haloperidol | nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D006220 | Haloperidol | norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D006220 | Haloperidol | Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| C010178 | heliotrine | heliotrine results in decreased expression of CYP3A5 mRNA | 26100227 |
| C001335 | hexachlorobutadiene | CYP3A5 protein results in increased metabolism of hexachlorobutadiene | 8555406 |
| D006854 | Hydrocortisone | Hydrocortisone results in increased expression of CYP3A5 mRNA | 23223499 |
| C031927 | hydroquinone | [CYP3A5 protein results in increased metabolism of bisphenol A] which results in increased chemical synthesis of hydroquinone | 21402134 |
| C058309 | hypaconitine | CYP3A5 protein results in increased metabolism of hypaconitine | 21550385 |
| C001654 | hyperforin | hyperforin results in increased expression of CYP3A5 mRNA | 24259679 |
| D007069 | Ifosfamide | CYP3A5 protein affects the metabolism of Ifosfamide | 15875221 |
| D007069 | Ifosfamide | CYP3A5 protein results in decreased ethylation of Ifosfamide | 15821045 |
| D007069 | Ifosfamide | CYP3A5 results in increased activity of Ifosfamide | 8717162 |
| D000068877 | Imatinib Mesylate | CYP3A5 protein results in decreased methylation of Imatinib Mesylate | 20977456 |
| C051890 | irinotecan | [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 | 15897249 |
| C051890 | irinotecan | CYP3A5 protein results in increased metabolism of irinotecan | 16271446 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in increased expression of CYP3A5 mRNA | 27392435 |
| D007654 | Ketoconazole | CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus] | 19384264 |
| D007654 | Ketoconazole | Ketoconazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D007654 | Ketoconazole | Ketoconazole inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA] | 24555085 |
| D007654 | Ketoconazole | Ketoconazole inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil] | 15731592 |
| D007654 | Ketoconazole | Ketoconazole inhibits the reaction [flunisolide results in increased expression of CYP3A5 mRNA] | 24555085 |
| D007654 | Ketoconazole | Ketoconazole inhibits the reaction [Fluticasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D007654 | Ketoconazole | Ketoconazole inhibits the reaction [Triamcinolone Acetonide results in increased expression of CYP3A5 mRNA] | 24555085 |
| D007654 | Ketoconazole | Ketoconazole results in decreased activity of CYP3A5 protein | 15557344|2630286 |
| D064747 | Lansoprazole | CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole] | 17377957 |
| C490728 | lapatinib | CYP3A5 protein results in increased metabolism of lapatinib | 26958860 |
| C490728 | lapatinib | [CYP3A5 protein results in increased metabolism of lapatinib] which results in increased activity of NFE2L2 protein | 26958860 |
| D008012 | Lidocaine | CYP3A5 protein results in decreased methylation of Lidocaine | 15383492 |
| D047311 | Luteolin | Luteolin inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 4-hydroxymidazolam] | 18191104 |
| D008294 | Malathion | CYP3A5 protein affects the metabolism of Malathion | 17110060 |
| D008468 | Meclizine | Meclizine inhibits the reaction [CYP3A5 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone] | 26239802 |
| D008468 | Meclizine | Meclizine inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone] | 26239802 |
| D003915 | Dextromethorphan | CYP3A5 protein affects the metabolism of Dextromethorphan | 15988119 |
| D003915 | Dextromethorphan | CYP3A5 protein results in decreased methylation of Dextromethorphan | 15383492 |
| D003915 | Dextromethorphan | CYP3A5 protein results in increased oxidation of Dextromethorphan | 15383492 |
| D008731 | Methoxychlor | CYP3A5 protein results in decreased methylation of Methoxychlor | 12433799 |
| D008874 | Midazolam | CYP3A5 protein affects the metabolism of Midazolam | 15801540 |
| D008874 | Midazolam | CYP3A5 gene polymorphism affects the metabolism of Midazolam | 15900284 |
| D008874 | Midazolam | CYP3A5 protein affects the metabolism of Midazolam | 15801540|1590028 |
| D008874 | Midazolam | CYP3A5 protein results in increased hydroxylation of Midazolam | 15383492|1549917 |
| D008874 | Midazolam | CYP3A5 protein results in increased metabolism of Midazolam | 26958860 |
| D008874 | Midazolam | "fructus schizandrae, radix ginseng, radix ophiopogonis drug combination affects the reaction [CYP3A5 protein affects the metabolism of Midazolam]" | 19557931 |
| D008874 | Midazolam | CYP3A5 protein affects the metabolism of Midazolam | 15801540 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 12538830 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA] | 12538830 |
| D015735 | Mifepristone | Mifepristone inhibits the reaction [Dexamethasone results in increased expression of CYP3A5 mRNA] | 12538830 |
| D009173 | Mycophenolic Acid | CYP3A5 protein results in increased methylation of Mycophenolic Acid | 15570183 |
| C114289 | N-acetyl-S--(1,2,3,4,4-pentachlorobutadienyl)cysteine sulfoxide | "CYP3A5 protein results in increased abundance of N-acetyl-S--(1,2,3,4,4-pentachlorobutadienyl)cysteine sulfoxide" | 8555406 |
| C049739 | N-acetyl-S-pentachloro-1,3-butadienylcysteine | "CYP3A5 protein results in increased oxidation of N-acetyl-S-pentachloro-1,3-butadienylcysteine" | 8555406 |
| C031721 | naphthalene | naphthalene results in increased expression of CYP3A5 mRNA | 20500019 |
| C028787 | N-desmethyltamoxifen | CYP3A5 protein results in increased metabolism of N-desmethyltamoxifen | 29285606 |
| C028787 | N-desmethyltamoxifen | "[CYP3A5 protein results in increased metabolism of N-desmethyltamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene" | 29285606 |
| C028787 | N-desmethyltamoxifen | N-desmethyltamoxifen results in decreased activity of CYP3A5 protein | 12419016 |
| C051752 | nefazodone | nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D019888 | Nelfinavir | Nelfinavir results in decreased activity of CYP3A5 protein | 15523003 |
| C454678 | N-ethyl-3-toluamide | CYP3A5 protein results in increased chemical synthesis of N-ethyl-3-toluamide | 11854147 |
| D009532 | Nickel | Nickel results in decreased expression of CYP3A5 mRNA | 24768652|2558310 |
| C574385 | N,N-didesmethyl-4-hydroxytamoxifen | "CYP3A5 protein results in increased metabolism of N,N-didesmethyl-4-hydroxytamoxifen" | 29285606 |
| C574385 | N,N-didesmethyl-4-hydroxytamoxifen | "[CYP3A5 protein results in increased metabolism of N,N-didesmethyl-4-hydroxytamoxifen] which results in increased abundance of N,N-didesmethyl-4-hydroxytamoxifen" | 29285606 |
| C058272 | norclozapine | CYP3A5 protein results in increased chemical synthesis of norclozapine | 18809730 |
| C036139 | norfluoxetine | norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D009661 | Nortriptyline | Nortriptyline results in increased metabolism of CYP3A5 protein | 18359012 |
| C016904 | norverapamil | norverapamil results in decreased activity of CYP3A5 protein | 15689501 |
| C464660 | obeticholic acid | obeticholic acid results in decreased expression of CYP3A5 mRNA | 27939613 |
| C025589 | ochratoxin A | CYP3A5 protein results in increased susceptibility to ochratoxin A | 11189750 |
| C025589 | ochratoxin A | ochratoxin A results in decreased expression of CYP3A5 mRNA | 26505656 |
| C025589 | ochratoxin A | ochratoxin A results in increased expression of CYP3A5 mRNA | 21834667 |
| D019319 | Okadaic Acid | CYP3A5 protein results in increased metabolism of and results in increased hydroxylation of and results in decreased susceptibility to Okadaic Acid | 26374342 |
| D009853 | Omeprazole | Omeprazole results in increased expression of CYP3A5 mRNA | 19118567 |
| C036006 | oxcarbazepine | oxcarbazepine results in increased activity of CYP3A5 protein | 12895138|1473106 |
| D010261 | Paraoxon | Paraoxon inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| D010278 | Parathion | CYP3A5 protein affects the metabolism of Parathion | 12669189|1707935 |
| D052638 | Particulate Matter | Particulate Matter analog results in decreased expression of CYP3A5 mRNA | 20026096 |
| C568608 | PCI 5002 | [PCI 5002 co-treated with Zinc] results in increased expression of CYP3A5 mRNA | 18593933 |
| C506614 | PD 0325901 | PD 0325901 results in increased expression of CYP3A5 mRNA | 24819614 |
| C471071 | perfluorohexanesulfonic acid | perfluorohexanesulfonic acid results in increased expression of CYP3A5 mRNA | 23567314 |
| C076994 | perfluorooctane sulfonic acid | perfluorooctane sulfonic acid results in decreased expression of CYP3A5 mRNA | 27153767 |
| D026023 | Permethrin | Permethrin results in increased expression of CYP3A5 mRNA | 19326768 |
| D010622 | Phencyclidine | CYP3A5 protein affects the metabolism of Phencyclidine | 16782764 |
| C058305 | phenethyl isothiocyanate | phenethyl isothiocyanate results in decreased expression of CYP3A5 mRNA | 20442190 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of CYP3A5 mRNA | 19159669 |
| D010634 | Phenobarbital | Phenobarbital results in increased expression of CYP3A5 mRNA | 10696073|1562911 |
| D010672 | Phenytoin | Phenytoin results in increased expression of CYP3A5 mRNA | 12673034 |
| D010830 | Physostigmine | Physostigmine inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] | 24555085 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CYP3A5 mRNA | 19710929 |
| D010936 | Plant Extracts | Plant Extracts results in decreased activity of CYP3A5 protein | 15900287 |
| D011374 | Progesterone | Progesterone results in increased expression of CYP3A5 mRNA | 22837389 |
| D011794 | Quercetin | Quercetin results in decreased expression of CYP3A5 mRNA | 21632981 |
| D011794 | Quercetin | Quercetin results in increased expression of CYP3A5 mRNA | 26238175 |
| D011796 | Quinacrine | CYP3A5 protein results in increased metabolism of Quinacrine | 16581945 |
| D064750 | Rabeprazole | CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole] | 17377957 |
| D017382 | Reactive Oxygen Species | CYP3A5 protein promotes the reaction [tetrandrine results in increased abundance of Reactive Oxygen Species] | 26302866 |
| D012110 | Reserpine | Reserpine results in increased expression of CYP3A5 protein | 8632764 |
| D012293 | Rifampin | Rifampin results in increased expression of CYP3A5 mRNA | 12040753|1267303 |
| D018967 | Risperidone | CYP3A5 gene polymorphism affects the abundance of Risperidone | 20332423 |
| D018967 | Risperidone | CYP3A5 protein affects the abundance of Risperidone | 20332423 |
| D018967 | Risperidone | CYP3A5 protein results in increased metabolism of Risperidone | 18708991 |
| D019438 | Ritonavir | Ritonavir results in decreased activity of CYP3A5 protein | 15523003 |
| C087123 | romidepsin | CYP3A5 protein affects the metabolism of romidepsin | 15635176 |
| D012643 | Selenium | Selenium results in decreased expression of CYP3A5 mRNA | 19244175 |
| C002979 | selenomethylselenocysteine | [selenomethylselenocysteine co-treated with irinotecan] results in increased expression of CYP3A5 | 15897249 |
| C009237 | senecionine | senecionine results in decreased expression of CYP3A5 mRNA | 26100227 |
| C009238 | senkirkine | senkirkine results in decreased expression of CYP3A5 mRNA | 26100227 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in decreased expression of CYP3A5 mRNA | 25895662 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in increased expression of CYP3A5 mRNA | 23806026 |
| D019821 | Simvastatin | CYP3A5 polymorphism affects the susceptibility to Simvastatin | 17192506 |
| D012906 | Smoke | decitabine inhibits the reaction [Smoke results in decreased expression of CYP3A5 mRNA] | 21095227 |
| D012906 | Smoke | Smoke results in decreased expression of CYP3A5 mRNA | 12538830 |
| D016559 | Tacrolimus | CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Lansoprazole] | 17377957 |
| D016559 | Tacrolimus | CYP3A5 affects the susceptibility to [Tacrolimus co-treated with Rabeprazole] | 17377957 |
| D016559 | Tacrolimus | CYP3A5 gene affects the susceptibility to Tacrolimus | 15723604 |
| D016559 | Tacrolimus | CYP3A5 gene polymorphism affects the metabolism of Tacrolimus | 15919447 |
| D016559 | Tacrolimus | CYP3A5 gene polymorphism affects the reaction [Ketoconazole results in decreased metabolism of Tacrolimus] | 19384264 |
| D016559 | Tacrolimus | CYP3A5 gene SNP affects the metabolism of Tacrolimus | 15729180 |
| D016559 | Tacrolimus | CYP3A5 protein affects the metabolism of Tacrolimus | 15502717|1580858 |
| D016559 | Tacrolimus | CYP3A5 protein polymorphism affects the metabolism of Tacrolimus | 15502717|1580858 |
| D016559 | Tacrolimus | CYP3A5 protein results in decreased methylation of Tacrolimus | 15951320 |
| C508967 | tamarixetin | tamarixetin results in increased expression of CYP3A5 mRNA | 26238175 |
| D013629 | Tamoxifen | CYP3A5 protein affects the metabolism of Tamoxifen | 15596297 |
| D013629 | Tamoxifen | CYP3A5 protein polymorphism affects the metabolism of Tamoxifen | 15596297 |
| D013629 | Tamoxifen | CYP3A5 protein results in increased metabolism of Tamoxifen | 29285606 |
| D013629 | Tamoxifen | "[CYP3A5 protein results in increased metabolism of Tamoxifen] which results in increased abundance of 1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene" | 29285606 |
| D013629 | Tamoxifen | Tamoxifen results in decreased activity of CYP3A5 protein | 12419016 |
| C112765 | tanespimycin | CYP3A5 protein affects the metabolism of tanespimycin | 15718306 |
| D013713 | Teniposide | CYP3A5 protein results in decreased methylation of Teniposide | 8114683 |
| D016593 | Terfenadine | CYP3A5 protein affects the metabolism of Terfenadine | 15383492 |
| D013739 | Testosterone | CYP3A5 protein results in increased hydroxylation of Testosterone | 15383492|1549917 |
| D013739 | Testosterone | Meclizine inhibits the reaction [CYP3A5 protein results in increased hydroxylation of Testosterone] | 26239802 |
| D013739 | Testosterone | [Testosterone co-treated with Calcitriol] results in increased expression of CYP3A5 mRNA | 21592394 |
| D013739 | Testosterone | Testosterone results in increased expression of CYP3A5 mRNA | 21592394 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CYP3A5 mRNA | 20106945|2163298 |
| C582340 | tetradecabromodiphenoxybenzene | tetradecabromodiphenoxybenzene analog results in increased expression of CYP3A5 mRNA | 25222814 |
| C009438 | tetrandrine | CYP3A5 protein promotes the reaction [tetrandrine results in decreased abundance of Glutathione] | 26302866 |
| C009438 | tetrandrine | CYP3A5 protein promotes the reaction [tetrandrine results in decreased expression of BCL2 protein] | 26302866 |
| C009438 | tetrandrine | CYP3A5 protein promotes the reaction [tetrandrine results in increased abundance of Reactive Oxygen Species] | 26302866 |
| C009438 | tetrandrine | CYP3A5 protein promotes the reaction [tetrandrine results in increased expression of CASP3 protein] | 26302866 |
| C009438 | tetrandrine | CYP3A5 protein results in increased glutathionylation of tetrandrine | 21992520 |
| C009438 | tetrandrine | CYP3A5 protein results in increased susceptibility to tetrandrine | 26302866 |
| D013792 | Thalidomide | CYP3A5 protein results in increased hydroxylation of Thalidomide | 20443640 |
| D013792 | Thalidomide | [CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide | 20443640 |
| D013792 | Thalidomide | CYP3A5 protein results in increased metabolism of Thalidomide | 28745489 |
| D013792 | Thalidomide | Thalidomide results in increased expression of CYP3A5 mRNA | 28496040 |
| D013792 | Thalidomide | CYP3A5 protein results in increased hydroxylation of Thalidomide | 20443640 |
| D013792 | Thalidomide | [CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide | 20443640 |
| D013852 | Thiotepa | CYP3A5 gene SNP affects the export of Thiotepa | 19076156 |
| D013852 | Thiotepa | CYP3A5 protein affects the susceptibility to Thiotepa | 19076156 |
| D013988 | Ticlopidine | CYP3A5 protein results in increased oxidation of and results in increased cleavage of Ticlopidine metabolite | 19170597 |
| D014196 | Trazodone | Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] | 12584149 |
| D014222 | Triamcinolone Acetonide | Ketoconazole inhibits the reaction [Triamcinolone Acetonide results in increased expression of CYP3A5 mRNA] | 24555085 |
| D014222 | Triamcinolone Acetonide | Triamcinolone Acetonide results in increased expression of CYP3A5 mRNA | 24555085 |
| D013721 | Triethylenephosphoramide | CYP3A5 gene SNP affects the export of Triethylenephosphoramide | 19076156 |
| D013721 | Triethylenephosphoramide | CYP3A5 protein affects the susceptibility to Triethylenephosphoramide | 19076156 |
| C005445 | triphenyl phosphate | triphenyl phosphate metabolite results in decreased expression of CYP3A5 mRNA | 25350880 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in increased expression of CYP3A5 mRNA" | 25242413 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of CYP3A5 mRNA" | 26179874 |
| C057693 | troglitazone | CYP3A5 protein results in increased metabolism of troglitazone | 19356091 |
| C057693 | troglitazone | troglitazone results in decreased expression of CYP3A5 | 15618651 |
| D014217 | Troleandomycin | Troleandomycin inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil] | 15731592 |
| D014217 | Troleandomycin | Troleandomycin results in decreased activity of CYP3A5 protein | 15557344 |
| D014217 | Troleandomycin | Troleandomycin results in decreased activity of CYP3A5 | 10910959 |
| C113580 | U 0126 | Dactinomycin inhibits the reaction [U 0126 results in increased expression of CYP3A5 mRNA] | 24819614 |
| C113580 | U 0126 | U 0126 results in increased expression of CYP3A5 mRNA | 24819614 |
| D014635 | Valproic Acid | Valproic Acid results in decreased expression of CYP3A5 mRNA | 29154799 |
| D000068756 | Valsartan | CYP3A5 gene affects the susceptibility to Valsartan | 22149319 |
| D014700 | Verapamil | Verapamil results in decreased activity of CYP3A5 protein | 15689501 |
| D014750 | Vincristine | [CYP3A5 gene polymorphism results in increased activity of CYP3A5 protein] which results in increased metabolism of Vincristine | 21225912|2122591 |
| D014750 | Vincristine | CYP3A5 protein results in increased metabolism of Vincristine | 21225912 |
| D002762 | Cholecalciferol | CYP3A5 protein results in increased hydroxylation of Cholecalciferol | 16207822 |
| D014810 | Vitamin E | Vitamin E results in decreased expression of CYP3A5 mRNA | 19244175 |
| D065819 | Voriconazole | Voriconazole results in decreased activity of CYP3A5 protein | 12013365 |
| D014859 | Warfarin | CYP3A5 gene polymorphism affects the susceptibility to Warfarin | 19752777 |
| D014859 | Warfarin | CYP3A5 protein affects the susceptibility to Warfarin | 19752777 |
| D015032 | Zinc | [PCI 5002 co-treated with Zinc] results in increased expression of CYP3A5 mRNA | 18593933 |
| C088658 | zoledronic acid | zoledronic acid results in increased expression of CYP3A5 mRNA | 24714768 |