Gene: OR1Q1

158131
HSTPCR106|OR1Q2|OR1Q3|OR9-25|OR9-A|OST226|OST226OR9-A|TPCR106
olfactory receptor family 1 subfamily Q member 1
protein-coding
9q33.2
Ensembl:ENSG00000165202 Vega:OTTHUMG00000020615 UniprotKB:Q15612
NC_000009.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.842e-1 (AD)  8.378e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1329957chr9:122615226 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR1L30.507
KRTAP9-70.476
IGSF220.474
CTAGE90.466
CRYGN0.452
LOXHD10.451
KERA0.448
DCSTAMP0.441
CCDC330.437
OR1L10.427

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EFEMP1-0.289
C2orf73-0.281
GLIPR1L2-0.271
CAMKMT-0.266
COLCA2-0.258
PAX6-0.257
GABRG1-0.256
SLC25A53-0.255
CCDC121-0.251
BMPR1B-0.25

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of OR1Q1 gene27153756
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of OR1Q1 mRNA"17331233
C006780bisphenol Abisphenol A results in decreased expression of OR1Q1 mRNA25181051
D018038Sodium SeleniteSodium Selenite results in decreased expression of OR1Q1 mRNA18175754

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004888transmembrane signaling receptor activity-IBA21873635  
GO:0004930G-protein coupled receptor activity-IEA-  
GO:0004984olfactory receptor activity-IBA21873635  
GO:0004984olfactory receptor activity-NAS9119360  
GO ID GO Term Qualifier Evidence PubMed
GO:0007186G-protein coupled receptor signaling pathway-IBA21873635  
GO:0007608sensory perception of smell-NAS9119360  
GO:0050911detection of chemical stimulus involved in sensory perception of smell-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-NAS9119360  
KEGG ID KEGG Term
hsa04740Olfactory transduction
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-381753Olfactory Signaling PathwayTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-418555G alpha (s) signalling eventsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal