Gene: KIAA2026

158358
-
KIAA2026
protein-coding
9p24.1
Ensembl:ENSG00000183354 Vega:OTTHUMG00000019507 UniprotKB:Q5HYC2
NC_000009.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.676e-1 (AD)  7.252e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1993912chr9:5987781 (GRCh38.p7)A>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BPTF0.927
RSF10.926
GPATCH2L0.919
USP340.913
WDFY30.91
TAOK10.907
GIGYF20.898
ZC3H130.89
FAM208A0.888
UBXN70.887

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.574
OR4F5-0.566
PLA2G5-0.25
APOA1-0.232
S100A14-0.225
HMX1-0.224
NANOGNB-0.207
FGA-0.206
NKX6-1-0.2
S100A1-0.2

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of KIAA2026 gene27153756
C006780bisphenol Abisphenol A results in decreased expression of KIAA2026 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA2026 mRNA28628672
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA2026 mRNA28628672
C118739entinostatentinostat results in decreased expression of KIAA2026 mRNA27188386
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIAA2026 mRNA22079256
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA2026 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of KIAA2026 mRNA28628672
C544151jinfukangjinfukang results in decreased expression of KIAA2026 mRNA27392435
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of KIAA2026 mRNA28001369
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KIAA2026 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of KIAA2026 mRNA22079256
D014520UrethaneUrethane results in increased expression of KIAA2026 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of KIAA2026 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of KIAA2026 mRNA23179753|2800136
D014635Valproic AcidValproic Acid results in decreased methylation of KIAA2026 gene29154799
C111237vorinostatvorinostat results in decreased expression of KIAA2026 mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal