Gene info: ID 1588

Gene: CYP19A1

GENE ID: 1588

Synonyms: ARO|ARO1|CPV1|CYAR|CYP19|CYPXIX|P-450AROM

Description: cytochrome P450 family 19 subfamily A member 1

Gene type: protein-coding

Location: 15q21.2

dbXrefs: Ensembl:ENSG00000137869 MIM:107910 Vega:OTTHUMG00000131747 UniprotKB:P11511

RefSeq: NG_007982.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: ND|AD

# Publications: 14

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 5.668e-1 (AD) 4.764e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
CCL7	0.965
IDO1	0.961
KRTAP20-1	0.952
CCL8	0.94
KRT75	0.932
RUFY4	0.929
ZBP1	0.927
IL27	0.91
HIST1H2AJ	0.906
LGALS14	0.893

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
SNX22	-0.299
ATP6V1E2	-0.297
HCN2	-0.279
KCNN1	-0.267
SCRT1	-0.265
NME5	-0.258
ADAMTSL2	-0.256
FOXRED2	-0.254
GNG7	-0.244
ARSE	-0.242

ID	Drug Name	Drug Type	CAS Num	Status	Role
DB00184	Nicotine	Small Molecule	54-11-5	Approved	Target
DB00357	Aminoglutethimide	Small Molecule	125-84-8	Approved\|Investigational	Target
DB00655	Estrone	Small Molecule	53-16-7	Approved	Target
DB00894	Testolactone	Small Molecule	968-93-4	Approved\|Investigational	Target
DB00990	Exemestane	Small Molecule	107868-30-4	Approved\|Investigational	Target
DB01006	Letrozole	Small Molecule	112809-51-5	Approved\|Investigational	Target
DB01026	Ketoconazole	Small Molecule	65277-42-1	Approved\|Investigational	Target
DB01217	Anastrozole	Small Molecule	120511-73-1	Approved\|Investigational	Target
DB02342	2-Methoxyestradiol	Small Molecule	362-07-2	Investigational	Target
DB03467	Naringenin	Small Molecule	480-41-1	Experimental	Target
DB04539	Glyphosate	Small Molecule	1071-83-6	Experimental	Target
DB05749	MPI-674	Small Molecule	-	Investigational	Target
DB00072	Trastuzumab	BiotechDrug	180288-69-1	Approved\|Investigational	Enzyme
DB00197	Troglitazone	Small Molecule	97322-87-7	Investigational\|Withdrawn	Enzyme
DB00255	Diethylstilbestrol	Small Molecule	56-53-1	Approved\|Investigational	Enzyme
DB00257	Clotrimazole	Small Molecule	23593-75-1	Approved	Enzyme
DB00269	Chlorotrianisene	Small Molecule	569-57-3	Investigational\|Withdrawn	Enzyme
DB00292	Etomidate	Small Molecule	33125-97-2	Approved	Enzyme
DB00333	Methadone	Small Molecule	76-99-3	Approved	Enzyme
DB00358	Mefloquine	Small Molecule	53230-10-7	Approved\|Investigational	Enzyme
DB00367	Levonorgestrel	Small Molecule	797-63-7	Approved\|Investigational	Enzyme
DB00389	Carbimazole	Small Molecule	22232-54-8	Approved\|Investigational	Enzyme
DB00443	Betamethasone	Small Molecule	378-44-9	Approved	Enzyme
DB00481	Raloxifene	Small Molecule	84449-90-1	Approved\|Investigational	Enzyme
DB00624	Testosterone	Small Molecule	58-22-0	Approved\|Investigational	Enzyme
DB00675	Tamoxifen	Small Molecule	10540-29-1	Approved	Enzyme
DB00856	Chlorphenesin	Small Molecule	104-29-0	Approved\|Withdrawn	Enzyme
DB00857	Terbinafine	Small Molecule	91161-71-6	Approved\|Investigational	Enzyme
DB00858	Drostanolone	Small Molecule	58-19-5	Approved\|Illicit	Enzyme
DB00882	Clomifene	Small Molecule	911-45-5	Approved\|Investigational	Enzyme
DB00917	Dinoprostone	Small Molecule	363-24-6	Approved	Enzyme
DB00926	Etretinate	Small Molecule	54350-48-0	Withdrawn	Enzyme
DB00974	Edetic Acid	Small Molecule	60-00-4	Approved	Enzyme
DB00984	Nandrolone phenpropionate	Small Molecule	62-90-8	Approved\|Illicit\|Investigational	Enzyme
DB00990	Exemestane	Small Molecule	107868-30-4	Approved\|Investigational	Enzyme
DB01006	Letrozole	Small Molecule	112809-51-5	Approved\|Investigational	Enzyme
DB01007	Tioconazole	Small Molecule	65899-73-2	Approved	Enzyme
DB01065	Melatonin	Small Molecule	73-31-4	Approved\|Nutraceutical	Enzyme
DB01110	Miconazole	Small Molecule	22916-47-8	Approved\|Investigational	Enzyme
DB01127	Econazole	Small Molecule	27220-47-9	Approved	Enzyme
DB01217	Anastrozole	Small Molecule	120511-73-1	Approved\|Investigational	Enzyme
DB01227	Levomethadyl Acetate	Small Molecule	1477-40-3	Approved\|Investigational	Enzyme
DB01229	Paclitaxel	Small Molecule	33069-62-4	Approved	Enzyme
DB01234	Dexamethasone	Small Molecule	50-02-2	Approved\|Investigational	Enzyme
DB01406	Danazol	Small Molecule	17230-88-5	Approved	Enzyme
DB02901	Stanolone	Small Molecule	521-18-6	Illicit\|Investigational	Enzyme
DB04794	Bifonazole	Small Molecule	60628-96-8	Approved\|Investigational	Enzyme
DB04839	Cyproterone acetate	Small Molecule	427-51-0	Approved\|Investigational	Enzyme
DB05804	Prasterone sulfate	Small Molecule	651-48-9	Investigational	Enzyme
DB05875	substance P	BiotechDrug	-	Investigational	Enzyme
DB06147	Sulfathiazole	Small Molecule	72-14-0	Approved	Enzyme
DB06710	Methyltestosterone	Small Molecule	58-18-4	Approved	Enzyme
DB06719	Buserelin	BiotechDrug	57982-77-1	Approved\|Investigational	Enzyme
DB08804	Nandrolone decanoate	Small Molecule	360-70-3	Approved\|Illicit	Enzyme
DB09389	Norgestrel	Small Molecule	6533-00-2	Approved	Enzyme
DB13943	Testosterone cypionate	Small Molecule	58-20-8	Approved	Enzyme
DB13944	Testosterone enanthate	Small Molecule	315-37-7	Approved	Enzyme
DB13946	Testosterone undecanoate	Small Molecule	5949-44-0	Approved\|Investigational	Enzyme
DB13951	Stanolone acetate	Small Molecule	1164-91-6	Experimental	Enzyme

ID	Drug Name	Action	PubMed
C495657	1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane	"1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane results in decreased expression of CYP19A1 mRNA"	20840852
C090859	1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole	1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole results in decreased activity of CYP19A1 protein	15964185
C090859	1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole	1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole results in decreased expression of CYP19A1 mRNA	15964185
C002029	17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol	"17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CYP19A1 mRNA"	15210295
C055238	1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene	"[1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene co-treated with LHB protein] results in decreased expression of CYP19A1 mRNA"	23333615
C055238	1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene	"1-chloro-4-(2,2-dichloro-1-(4-chlorophenyl)ethenyl)-3-(methylsulfonyl)benzene results in decreased expression of CYP19A1 mRNA"	23333615
C054919	2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene	"2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene results in increased activity of CYP19A1 protein"	18195494
C530171	2,2,2,-trichloro-1-(3,4-dichlorophenyl)-ethylacetate	"2,2,2,-trichloro-1-(3,4-dichlorophenyl)-ethylacetate results in increased expression of CYP19A1 mRNA"	22119440
C120129	2,2',3,4',5',6-hexachlorobiphenyl	"2,2',3,4',5',6-hexachlorobiphenyl metabolite results in increased expression of CYP19A1 mRNA"	16216300
C120129	2,2',3,4',5',6-hexachlorobiphenyl	"2,2',3,4',5',6-hexachlorobiphenyl results in increased expression of CYP19A1 mRNA"	16216300
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in decreased activity of CYP19A1 protein"	16177243
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether metabolite results in decreased activity of CYP19A1 protein"	18022659
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether metabolite results in increased expression of CYP19A1 mRNA"	18248924
C511295	2,2',4,4'-tetrabromodiphenyl ether	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein"	23146758
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of CYP19A1 mRNA"	23146758
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]"	28284726
C511295	2,2',4,4'-tetrabromodiphenyl ether	"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CYP19A1 protein"	28284726
C511295	2,2',4,4'-tetrabromodiphenyl ether	"Fadrozole inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein]"	23146758
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of CYP19A1 protein]	12839940
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]	28571770
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C093973	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane binds to and results in decreased activity of CYP19A1 protein"	22120136
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]"	22120136
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased expression of CYP19A1 mRNA"	22120136
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]"	16737795\|1941451
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased activity of CYP19A1 protein"	22120136
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in decreased expression of CYP19A1 mRNA"	22120136
C029498	2,3-bis(3'-hydroxybenzyl)butane-1,4-diol	"2,3-bis(3'-hydroxybenzyl)butane-1,4-diol results in decreased activity of CYP19A1 protein"	15876411
C029497	2,3-bis(3'-hydroxybenzyl)butyrolactone	"2,3-bis(3'-hydroxybenzyl)butyrolactone results in decreased activity of CYP19A1 protein"	15876411
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [LHB protein results in increased expression of CYP19A1 mRNA]"	27832956
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP19A1 mRNA"	27832956
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of CYP19A1 mRNA"	22262711
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP19A1 mRNA"	22262711
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP19A1 mRNA"	25765474
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein"	16151981
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CYP19A1 protein"	16151981
C009828	2,4,5,2',5'-pentachlorobiphenyl	"2,4,5,2',5'-pentachlorobiphenyl metabolite results in increased expression of CYP19A1 mRNA"	16216300
C009828	2,4,5,2',5'-pentachlorobiphenyl	"2,4,5,2',5'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA"	16216300
C004554	2,4,6-tribromophenol	"2,4,6-tribromophenol results in increased activity of CYP19A1 protein"	16177243
C004554	2,4,6-tribromophenol	"2,4,6-tribromophenol results in increased expression of CYP19A1 mRNA"	17447562
C024564	2,4,6-trichlorophenol	"2,4,6-trichlorophenol results in decreased expression of CYP19A1 mRNA"	21296122
C013930	2,4-dibromophenol	"2,4-dibromophenol results in increased expression of CYP19A1 mRNA"	17447562
C553231	2-(4-hydroxyphenyl)-3-phenylpent-2-enoic acid (4-(2-dimethylaminoethoxy)phenyl)amide	2-(4-hydroxyphenyl)-3-phenylpent-2-enoic acid (4-(2-dimethylaminoethoxy)phenyl)amide results in increased expression of CYP19A1 mRNA	19549922
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]	28571770
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C032038	2-bromophenol	2-bromophenol results in increased expression of CYP19A1 mRNA	17447562
C010724	2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine	"Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]"	15242824
C010724	2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine	"CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine"	15242824
C010724	2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine	"formestane inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]"	15242824
C405442	2-methoxyoestrone-3-O-sulphamate	2-methoxyoestrone-3-O-sulphamate inhibits the reaction [Dinoprostone results in increased activity of CYP19A1 protein]	15862962
C405442	2-methoxyoestrone-3-O-sulphamate	2-methoxyoestrone-3-O-sulphamate inhibits the reaction [IL6 protein results in increased activity of CYP19A1 protein]	15862962
C405442	2-methoxyoestrone-3-O-sulphamate	2-methoxyoestrone-3-O-sulphamate inhibits the reaction [TNF protein results in increased activity of CYP19A1 protein]	15862962
C405442	2-methoxyoestrone-3-O-sulphamate	2-methoxyoestrone-3-O-sulphamate results in decreased activity of CYP19A1 protein	15862962
C032790	3,3',4,4',5,5'-hexabromobiphenyl	"3,3',4,4',5,5'-hexabromobiphenyl results in increased expression of CYP19A1 mRNA"	17447562
C036685	3,3',4,4'-tetrabromobiphenyl	"3,3',4,4'-tetrabromobiphenyl results in increased expression of CYP19A1 mRNA"	17447562
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane analog results in increased expression of CYP19A1 mRNA"	11294972
C016392	3,3'-diindolylmethane	"3,3'-diindolylmethane results in increased expression of CYP19A1 mRNA"	11294972
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl inhibits the reaction [LHB protein results in increased expression of CYP19A1 mRNA]"	27832956
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CYP19A1 mRNA"	27832956
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CYP19A1 mRNA"	16216300\|2057491
C023035	3,4,5,3',4'-pentachlorobiphenyl	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
C023035	3,4,5,3',4'-pentachlorobiphenyl	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP19A1 mRNA"	25765474
C023035	3,4,5,3',4'-pentachlorobiphenyl	"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein"	16151981
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased activity of CYP19A1 protein"	16151981
C091768	3'-methoxy-4'-nitroflavone	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
C496751	4-(1H-imidazol-1-yl)retinoic acid	4-(1H-imidazol-1-yl)retinoic acid results in decreased activity of CYP19A1 protein	17145897
C038864	4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased activity of CYP19A1 protein"	16996190
C038864	4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid	"4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of CYP19A1 mRNA"	16996190
C088860	4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline	"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Estradiol results in increased activity of CYP19A1 protein]"	12839940
C088860	4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline	"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline results in decreased activity of CYP19A1 protein"	15955695
C116322	4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine	4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine results in increased expression of CYP19A1 mRNA	21352547
C055492	4-hydroxy-N-desmethyltamoxifen	CYP19A1 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen	29285606
C055492	4-hydroxy-N-desmethyltamoxifen	[CYP19A1 protein results in increased metabolism of 4-hydroxy-N-desmethyltamoxifen] which results in increased abundance of 4-hydroxy-N-desmethyltamoxifen metabolite	29285606
C024836	4-nitrophenol	4-nitrophenol results in decreased expression of CYP19A1 mRNA	24070737
C041594	4-nonylphenol	4-nonylphenol results in decreased activity of CYP19A1 protein	20377353
C041594	4-nonylphenol	4-nonylphenol results in decreased expression of CYP19A1 mRNA	29029336
C041594	4-nonylphenol	4-nonylphenol results in decreased expression of CYP19A1 protein	29029336
C041594	4-nonylphenol	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA	29029336
C041594	4-nonylphenol	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein	29029336
C105260	4-tert-octylphenol	4-tert-octylphenol results in increased expression of CYP19A1 protein	20850518
C105260	4-tert-octylphenol	4-tert-octylphenol results in decreased expression of CYP19A1 mRNA	29029336
C105260	4-tert-octylphenol	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA	29029336
C105260	4-tert-octylphenol	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein	29029336
C053876	6-isopropoxy-9-oxoxanthene-2-carboxylic acid	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]	28571770
C053876	6-isopropoxy-9-oxoxanthene-2-carboxylic acid	6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C053876	6-isopropoxy-9-oxoxanthene-2-carboxylic acid	"6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]"	20678559
C053876	6-isopropoxy-9-oxoxanthene-2-carboxylic acid	"6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C558735	7-(3,4-difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)-2H-chromen-2-one	"7-(3,4-difluorophenoxy)-4-(1H-imidazol-1-ylmethyl)-2H-chromen-2-one results in decreased activity of CYP19A1 protein"	21341743
C059353	7-hydroxyflavanone	7-hydroxyflavanone results in decreased activity of CYP19A1 protein	15319488
C429845	7-hydroxyflavone	7-hydroxyflavone results in decreased activity of CYP19A1 protein	15319488
C529431	8-2 fluorotelomer alcohol	8-2 fluorotelomer alcohol results in increased expression of CYP19A1 mRNA	23142464
D000079	Acetaldehyde	[CGA protein results in increased abundance of Acetaldehyde] which results in increased expression of CYP19A1 mRNA	22285649
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP19A1 mRNA	26690555
D000082	Acetaminophen	Acetaminophen results in increased expression of CYP19A1 mRNA	25607892
D000082	Acetaminophen	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA	25607892
C016601	afimoxifene	afimoxifene results in increased expression of CYP19A1 mRNA	19549922
C016601	afimoxifene	CYP19A1 protein results in increased metabolism of afimoxifene	29285606
C016601	afimoxifene	[CYP19A1 protein results in increased metabolism of afimoxifene] which results in increased abundance of afimoxifene metabolite	29285606
C012170	aflatoxicol	[CYP19A1 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxicol	21296134
C012170	aflatoxicol	[finrozole inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]] which results in decreased chemical synthesis of aflatoxicol	21296134
C012170	aflatoxicol	[Tamoxifen inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]] which results in decreased chemical synthesis of aflatoxicol	21296134
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of CYP19A1 mRNA	21296134\|2340293
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of CYP19A1 protein	21296134
D016604	Aflatoxin B1	alpha-naphthoflavone inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134
D016604	Aflatoxin B1	CYP19A1 protein results in increased metabolism of Aflatoxin B1	21296134
D016604	Aflatoxin B1	[CYP19A1 protein results in increased metabolism of Aflatoxin B1] which results in increased chemical synthesis of aflatoxicol	21296134
D016604	Aflatoxin B1	Estriol inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134
D016604	Aflatoxin B1	finrozole inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134\|2340293
D016604	Aflatoxin B1	[finrozole inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]] which results in decreased chemical synthesis of aflatoxicol	21296134
D016604	Aflatoxin B1	Tamoxifen inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134
D016604	Aflatoxin B1	[Tamoxifen inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]] which results in decreased chemical synthesis of aflatoxicol	21296134
C046926	AH 23848	AH 23848 inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]	28571770
C046926	AH 23848	AH 23848 inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C046926	AH 23848	"AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]"	20678559
C046926	AH 23848	"AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
D000420	Albuterol	[Cyproterone co-treated with Albuterol] results in decreased expression of CYP19A1	17822730
D000452	Aldrin	Aldrin results in increased activity of CYP19A1 protein	16996190
D000452	Aldrin	Aldrin results in increased expression of CYP19A1 mRNA	16996190
C103303	alitretinoin	[alitretinoin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein	15941851
C103303	alitretinoin	alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]	16357189
C103303	alitretinoin	alitretinoin inhibits the reaction [NR5A2 protein results in increased expression of CYP19A1 mRNA]	16357189
C103303	alitretinoin	alitretinoin results in increased expression of CYP19A1 mRNA	15941851
C103303	alitretinoin	alitretinoin promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA]	12706301
C103303	alitretinoin	alitretinoin results in decreased expression of CYP19A1 mRNA	12706301
C005915	Allura Red AC Dye	Allura Red AC Dye results in decreased activity of CYP19A1 protein	18310892
C095512	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]"	28571770
C095512	alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide	"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]"	28571770
D013196	Dihydrotestosterone	Dihydrotestosterone promotes the reaction [[Estradiol co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA]	16641147
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of CYP19A1 mRNA	16641147
D013196	Dihydrotestosterone	Dihydrotestosterone results in decreased expression of CYP19A1 mRNA	22948218
D013196	Dihydrotestosterone	Dihydrotestosterone results in decreased expression of CYP19A1 protein	22948218
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of CYP19A1 mRNA	15525594\|2127344
D013196	Dihydrotestosterone	Dihydrotestosterone results in increased expression of CYP19A1 protein	15525594
D013196	Dihydrotestosterone	FSHB protein inhibits the reaction [Dihydrotestosterone results in decreased expression of CYP19A1 protein]	22948218
C011512	alpha-naphthoflavone	alpha-naphthoflavone binds to and results in decreased activity of CYP19A1 protein	9435150
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134
C011512	alpha-naphthoflavone	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 protein]	20823264
C011512	alpha-naphthoflavone	"[alpha-naphthoflavone results in decreased activity of CYP19A1 protein] which results in decreased susceptibility to o,p'-DDT"	20678559
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in increased expression of CYP19A1 protein	20823264
C011512	alpha-naphthoflavone	alpha-naphthoflavone results in decreased activity of CYP19A1 protein	20678559
C005197	alternariol	alternariol results in increased expression of CYP19A1 mRNA	23665424
C068073	Am 580	Am 580 results in increased expression of CYP19A1 mRNA	15941851
D000616	Aminoglutethimide	Aminoglutethimide results in decreased activity of CYP19A1 protein	1659868
D000616	Aminoglutethimide	Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	16935330
D000616	Aminoglutethimide	"Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]"	15242824
D000616	Aminoglutethimide	Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]	15242824
D000616	Aminoglutethimide	Aminoglutethimide results in decreased activity of CYP19A1 protein	15968818\|1791001
D000616	Aminoglutethimide	Aminoglutethimide results in increased activity of CYP19A1 protein	20087668
D000616	Aminoglutethimide	Aminoglutethimide results in decreased activity of CYP19A1 protein	17081805
D000616	Aminoglutethimide	Aminoglutethimide results in decreased activity of CYP19A1 protein	14711788\|1527608
D017311	Amlodipine	Amlodipine results in decreased activity of CYP19A1 protein	26141389
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of CYP19A1 mRNA	16483693
D000658	Amoxicillin	Amoxicillin results in increased expression of CYP19A1	17822730
D000661	Amphetamine	CYP19A1 gene results in decreased susceptibility to Amphetamine	12884966
D000894	Anti-Inflammatory Agents, Non-Steroidal	"Anti-Inflammatory Agents, Non-Steroidal results in decreased activity of CYP19A1 protein"	15964185
D000894	Anti-Inflammatory Agents, Non-Steroidal	"Anti-Inflammatory Agents, Non-Steroidal results in decreased expression of CYP19A1 mRNA"	15964185
C090450	anastrozole	anastrozole results in decreased activity of CYP19A1 protein	15837728\|1600195
D000726	Androgen Antagonists	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA	25607892
D000728	Androgens	CYP19A1 protein affects the metabolism of Androgens	12839940
D000728	Androgens	CYP19A1 protein results in increased metabolism of Androgens	16670151
D000728	Androgens	Androgens affects the expression of CYP19A1	16019206
D000728	Androgens	CYP19A1 protein affects the metabolism of Androgens	16019206
D000728	Androgens	CYP19A1 protein affects the metabolism of Androgens	15983630\|1603984
D000728	Androgens	CYP19A1 protein results in increased metabolism of Androgens	10814527
D000728	Androgens	[CYP19A1 protein results in increased metabolism of Androgens] which results in increased chemical synthesis of Estrogens	10814527
D000728	Androgens	IL1B protein promotes the reaction [CYP19A1 protein affects the metabolism of Androgens]	15983630
D000728	Androgens	IL6 protein promotes the reaction [CYP19A1 protein affects the metabolism of Androgens]	15983630
D000728	Androgens	TNF protein promotes the reaction [CYP19A1 protein affects the metabolism of Androgens]	15983630
D000728	Androgens	[troglitazone results in decreased activity of CYP19A1 protein] inhibits the reaction [[CYP19A1 protein results in increased metabolism of Androgens] which results in increased chemical synthesis of Estrogens]	10814527
D015113	Androstane-3,17-diol	"Androstane-3,17-diol results in increased expression of CYP19A1 mRNA"	21273442
D000735	Androstenedione	CYP19A1 protein affects the metabolism of Androstenedione	12568797
D000735	Androstenedione	"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane inhibits the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]"	22120136
D000735	Androstenedione	Atrazine promotes the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]	22120136
D000735	Androstenedione	bisphenol A affects the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]	22120136
D000735	Androstenedione	CYP19A1 protein affects the metabolism of Androstenedione	12628686\|1603016
D000735	Androstenedione	CYP19A1 protein binds to and results in increased metabolism of Androstenedione	11522339
D000735	Androstenedione	CYP19A1 protein results in increased metabolism of Androstenedione	22120136\|2616259
D000735	Androstenedione	Methoxychlor affects the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]	22120136
D000735	Androstenedione	Methyltestosterone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
D000735	Androstenedione	Nandrolone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
D000735	Androstenedione	Testosterone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
D000735	Androstenedione	TNF protein promotes the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	16030167
D000735	Androstenedione	trestolone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
D000735	Androstenedione	tributyltin inhibits the reaction [CYP19A1 protein binds to and results in increased metabolism of Androstenedione]	11522339
D000735	Androstenedione	Androstenedione results in decreased expression of CYP19A1 mRNA	21439382
D000735	Androstenedione	[Androstenedione results in decreased expression of CYP19A1 mRNA] which results in decreased abundance of Estradiol	21439382
D000735	Androstenedione	Androstenedione results in increased expression of CYP19A1 mRNA	21273442
D000735	Androstenedione	bicalutamide inhibits the reaction [Androstenedione results in increased expression of CYP19A1 protein]	21273442
D000735	Androstenedione	CYP19A1 protein results in increased metabolism of Androstenedione	16569475
D000735	Androstenedione	Finasteride promotes the reaction [Androstenedione results in increased expression of CYP19A1 mRNA]	21273442
D000735	Androstenedione	formestane promotes the reaction [Androstenedione results in increased expression of CYP19A1 mRNA]	21273442
D000735	Androstenedione	CYP19A1 protein affects the metabolism of Androstenedione	16039845
D000735	Androstenedione	CYP19A1 protein results in increased oxidation of and affects the metabolism of Androstenedione	16002112
C023650	aniline	aniline analog results in decreased activity of CYP19A1 protein	16480277
C023650	aniline	aniline analog results in decreased expression of CYP19A1 mRNA	16480277
C034020	anthracene	anthracene results in increased expression of CYP19A1 protein	28803881
C034020	anthracene	[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of CYP19A1 protein	28803881
D047310	Apigenin	Apigenin results in decreased activity of CYP19A1 protein	10403137\|1531948
D047310	Apigenin	Apigenin results in decreased expression of CYP19A1 mRNA	16965912
D047310	Apigenin	Apigenin results in decreased activity of CYP19A1 protein	16023337
D047072	Aromatase Inhibitors	Aromatase Inhibitors binds to and results in decreased activity of CYP19A1 protein	16039845
D047072	Aromatase Inhibitors	Aromatase Inhibitors results in decreased activity of CYP19A1 protein	15837728\|1603448
D047072	Aromatase Inhibitors	Aromatase Inhibitors results in increased mutagenesis of CYP19A1 gene	28112739
D047072	Aromatase Inhibitors	CYP19A1 mutant form results in decreased susceptibility to Aromatase Inhibitors	28112739
D047072	Aromatase Inhibitors	Aromatase Inhibitors inhibits the reaction [CYP19A1 protein affects the chemical synthesis of Estrogens]	15992333
D001205	Ascorbic Acid	Ascorbic Acid results in increased expression of CYP19A1 mRNA	17901237
D001205	Ascorbic Acid	[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CYP19A1 mRNA	16443354
D001280	Atrazine	Atrazine results in increased expression of CYP19A1 mRNA	27495953
D001280	Atrazine	Atrazine results in decreased expression of CYP19A1 mRNA	25929836
D001280	Atrazine	Atrazine results in increased expression of CYP19A1 mRNA	26891955
D001280	Atrazine	Atrazine metabolite results in increased activity of CYP19A1 protein	11675267
D001280	Atrazine	Atrazine metabolite results in increased expression of CYP19A1 mRNA	11675267
D001280	Atrazine	Atrazine promotes the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]	22120136
D001280	Atrazine	Atrazine promotes the reaction [[NR5A1 protein binds to CYP19A1 gene] which results in increased expression of CYP19A1 mRNA]	17520059\|1752005
D001280	Atrazine	Atrazine results in decreased activity of CYP19A1 protein	17599374
D001280	Atrazine	Atrazine results in increased activity of CYP19A1 protein	10746939\|1167526
D001280	Atrazine	[Atrazine results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol	20087668
D001280	Atrazine	[Atrazine results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone	20087668
D001280	Atrazine	Atrazine results in increased expression of CYP19A1 mRNA	10746939\|1167526
D001280	Atrazine	[Chlorodiphenyl (54% Chlorine) co-treated with Atrazine] results in decreased activity of CYP19A1 protein	17599374
D001280	Atrazine	formestane inhibits the reaction [Atrazine results in increased activity of CYP19A1 protein]	10746939
D001280	Atrazine	NR5A1 protein affects the reaction [Atrazine results in increased expression of CYP19A1 mRNA]	18461179
D001280	Atrazine	NR5A1 protein promotes the reaction [Atrazine results in increased expression of CYP19A1 mRNA]	17331471
D001280	Atrazine	"[o,p'-DDT co-treated with Atrazine] results in increased activity of CYP19A1 protein"	17599374
D001280	Atrazine	SGK1 protein affects the reaction [Atrazine results in increased expression of CYP19A1 mRNA]	18461179
D001280	Atrazine	[vinclozolin co-treated with Atrazine] results in decreased activity of CYP19A1 protein	17599374
D001280	Atrazine	Atrazine results in increased expression of CYP19A1 mRNA	20723554\|2651823
D001280	Atrazine	Atrazine affects the expression of CYP19A1 protein	22285353
D001280	Atrazine	Atrazine inhibits the reaction [Chorionic Gonadotropin results in increased expression of CYP19A1 mRNA]	26923738
D001280	Atrazine	Atrazine inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]	23583632
D001280	Atrazine	Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
D001280	Atrazine	Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA]	23583632
D001280	Atrazine	Atrazine promotes the reaction [FSHB protein results in increased activity of CYP19A1 protein]	22120136
D001280	Atrazine	Atrazine results in increased activity of CYP19A1 protein	21126571
D001280	Atrazine	Atrazine results in increased expression of CYP19A1 mRNA	22120136\|2228535
D001280	Atrazine	U 0126 inhibits the reaction [Atrazine inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]	23583632
D001514	Bee Venoms	Bee Venoms results in increased activity of CYP19A1 protein	15894134
D001514	Bee Venoms	Bee Venoms results in increased expression of CYP19A1 mRNA	15894134
D001542	Benomyl	Benomyl results in increased activity of CYP19A1 protein	14691014
D001542	Benomyl	Benomyl results in increased expression of CYP19A1 mRNA	14691014\|2554321
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of CYP19A1 mRNA	19737606
C105430	benzofuran	benzofuran analog results in decreased activity of CYP19A1 protein	15968818
D001572	Benzofurans	Benzofurans results in increased expression of CYP19A1 mRNA	17447562
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of CYP19A1 mRNA	20064835\|2010694
D001564	Benzo(a)pyrene	[Benzo(a)pyrene co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP19A1 mRNA	20920559
D001564	Benzo(a)pyrene	[Benzo(a)pyrene co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP19A1 protein	20920559
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of CYP19A1 mRNA	20920559
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of CYP19A1 protein	20920559
D001564	Benzo(a)pyrene	Benzo(a)pyrene inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]	28284726
D004958	Estradiol	Dihydrotestosterone promotes the reaction [[Estradiol co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA]	16641147
D004958	Estradiol	[Estradiol co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA	16641147
D004958	Estradiol	Estradiol promotes the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	16641147
D004958	Estradiol	Estradiol results in increased expression of CYP19A1 mRNA	16641147
D004958	Estradiol	fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP19A1 mRNA]	16641147
D004958	Estradiol	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased activity of CYP19A1 protein]	12839940
D004958	Estradiol	"4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Estradiol results in increased activity of CYP19A1 protein]"	12839940
D004958	Estradiol	[Atrazine results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol	20087668
D004958	Estradiol	[Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol	20087668
D004958	Estradiol	CYP19A1 protein affects the chemical synthesis of Estradiol	16024248\|1603016
D004958	Estradiol	CYP19A1 protein results in increased chemical synthesis of Estradiol	16054388
D004958	Estradiol	Estradiol affects the expression of CYP19A1 mRNA	14699072
D004958	Estradiol	Estradiol promotes the reaction [ESR1 results in increased expression of CYP19A1 mRNA alternative form]	18462857
D004958	Estradiol	Estradiol promotes the reaction [ESR1 results in increased expression of CYP19A1 protein]	18462857
D004958	Estradiol	Estradiol promotes the reaction [ESR2 protein affects the expression of CYP19A1 mRNA]	20404318
D004958	Estradiol	Estradiol results in decreased expression of CYP19A1 mRNA	26921789
D004958	Estradiol	Estradiol results in increased activity of CYP19A1 protein	12839940\|1595569
D004958	Estradiol	Estradiol results in increased expression of CYP19A1 mRNA	16029874
D004958	Estradiol	Estradiol results in increased expression of CYP19A1 mRNA alternative form	18462857
D004958	Estradiol	Estradiol results in increased expression of CYP19A1 protein	18462857
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol promotes the reaction [ESR1 results in increased expression of CYP19A1 mRNA alternative form]]	18462857
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol promotes the reaction [ESR1 results in increased expression of CYP19A1 protein]]	18462857
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol results in increased expression of CYP19A1 mRNA alternative form]	18462857
D004958	Estradiol	resveratrol inhibits the reaction [Estradiol results in increased expression of CYP19A1 protein]	18462857
D004958	Estradiol	TNF protein promotes the reaction [CYP19A1 protein affects the chemical synthesis of Estradiol]	16030167
D004958	Estradiol	U 0126 inhibits the reaction [Estradiol results in increased expression of CYP19A1 mRNA alternative form]	18462857
D004958	Estradiol	"[Water Pollutants, Chemical results in increased activity of CYP19A1 protein] which results in decreased metabolism of Estradiol"	20466405
D004958	Estradiol	Estradiol affects the reaction [CYP19A1 affects the expression of BMP15 mRNA]	11985600
D004958	Estradiol	Estradiol affects the reaction [CYP19A1 affects the expression of GDF9 mRNA]	11985600
D004958	Estradiol	Estradiol affects the reaction [CYP19A1 affects the expression of IGF1 mRNA]	11985600
D004958	Estradiol	Estradiol affects the reaction [CYP19A1 affects the expression of IGF1R mRNA]	11985600
D004958	Estradiol	Estradiol affects the reaction [CYP19A1 affects the expression of PGR mRNA]	11985600
D004958	Estradiol	Estradiol affects the reaction [CYP19A1 affects the expression of VEGFA mRNA]	11985600
D004958	Estradiol	[[NR5A2 protein results in increased phosphorylation of and results in increased activity of NOS3 protein] which results in decreased activity of CYP19A1 protein] which results in decreased chemical synthesis of Estradiol	18628394
D004958	Estradiol	Estradiol results in increased expression of CYP19A1 mRNA	14595849
D004958	Estradiol	[Androstenedione results in decreased expression of CYP19A1 mRNA] which results in decreased abundance of Estradiol	21439382
D004958	Estradiol	[bisphenol A results in decreased expression of CYP19A1 mRNA] which affects the abundance of Estradiol	18191889
D004958	Estradiol	[BMP2 protein results in increased expression of CYP19A1 mRNA] promotes the reaction [FSHB protein results in increased abundance of Estradiol]	22067323
D004958	Estradiol	[BMP4 protein results in increased expression of CYP19A1 mRNA] promotes the reaction [FSHB protein results in increased abundance of Estradiol]	22067323
D004958	Estradiol	[BMP7 protein results in increased expression of CYP19A1 mRNA] promotes the reaction [FSHB protein results in increased abundance of Estradiol]	22067323
D004958	Estradiol	CYP19A1 protein results in increased chemical synthesis of Estradiol	16569475
D004958	Estradiol	Estradiol affects the activity of CYP19A1 protein	21068160
D004958	Estradiol	Estradiol results in decreased expression of CYP19A1 mRNA	18191889
D004958	Estradiol	[Testosterone results in increased expression of CYP19A1 mRNA] which results in increased abundance of Estradiol	21273442
D004958	Estradiol	[Testosterone results in increased expression of CYP19A1 protein] which results in increased abundance of Estradiol	21273442
D004958	Estradiol	CYP19A1 protein results in increased chemical synthesis of Estradiol	21273442\|9435150
D001629	Bezafibrate	Bezafibrate results in decreased activity of CYP19A1 protein	19539015
D001629	Bezafibrate	Bezafibrate results in decreased expression of CYP19A1 mRNA	19539015
D001629	Bezafibrate	Bezafibrate inhibits the reaction [CYP19A1 gene mutant form results in decreased expression of ACADM mRNA]	11929713
D001629	Bezafibrate	Bezafibrate inhibits the reaction [CYP19A1 gene mutant form results in decreased expression of ACOX1 mRNA]	11929713
C053541	bicalutamide	bicalutamide inhibits the reaction [Androstenedione results in increased expression of CYP19A1 protein]	21273442
C053541	bicalutamide	bicalutamide inhibits the reaction [Testosterone results in increased expression of CYP19A1 protein]	21273442
C099952	bifenthrin	bifenthrin results in increased expression of CYP19A1 mRNA	24938463
C099952	bifenthrin	bifenthrin inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]	21251947
C036596	bifonazole	bifonazole results in decreased activity of CYP19A1 protein	15554355\|2449663
C004541	biochanin A	biochanin A binds to and results in decreased activity of CYP19A1 protein	9435150
C004541	biochanin A	biochanin A results in decreased activity of CYP19A1 protein	16965912
C004541	biochanin A	biochanin A results in decreased expression of CYP19A1 mRNA	16965912
C004541	biochanin A	[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein	16965912
C004541	biochanin A	[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA	16965912
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone affects the expression of CYP19A1 protein	28352085
C543008	bis(4-hydroxyphenyl)sulfone	bis(4-hydroxyphenyl)sulfone results in decreased expression of CYP19A1 mRNA	28352085
C088060	bisindolylmaleimide	bisindolylmaleimide results in decreased activity of CYP19A1 protein	15955695
C006780	bisphenol A	bisphenol A results in decreased activity of CYP19A1 protein	20377353
C006780	bisphenol A	bisphenol A promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A results in decreased activity of CYP19A1 protein	17599374
C006780	bisphenol A	bis(tri-n-butyltin)oxide promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	Chlordecone promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	nonylphenol promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 mRNA	16297413
C006780	bisphenol A	bisphenol A results in decreased expression of CYP19A1 mRNA	23174456
C006780	bisphenol A	bisphenol A affects the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]	22120136
C006780	bisphenol A	bisphenol A inhibits the reaction [FSHB results in increased expression of CYP19A1 mRNA]	20064783
C006780	bisphenol A	bisphenol A inhibits the reaction [FSHB results in increased expression of CYP19A1 protein]	20064783
C006780	bisphenol A	bisphenol A promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A results in decreased activity of CYP19A1 protein	12849724\|1759937
C006780	bisphenol A	bisphenol A results in decreased expression of CYP19A1 mRNA	22120136\|2232705
C006780	bisphenol A	bisphenol A results in decreased expression of CYP19A1 protein	27112698
C006780	bisphenol A	bisphenol A results in increased activity of CYP19A1 protein	12849724
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 mRNA	25784278\|2768578
C006780	bisphenol A	bis(tri-n-butyltin)oxide promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	[Dichlorodiphenyl Dichloroethylene co-treated with bisphenol A] results in decreased activity of CYP19A1 protein	17599374
C006780	bisphenol A	nonylphenol promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C006780	bisphenol A	bisphenol A affects the expression of CYP19A1 mRNA	28970132
C006780	bisphenol A	bisphenol A affects the reaction [CYP19A1 affects the expression of BMP15 mRNA]	11985600
C006780	bisphenol A	bisphenol A affects the reaction [CYP19A1 affects the expression of GDF9 mRNA]	11985600
C006780	bisphenol A	bisphenol A affects the reaction [CYP19A1 affects the expression of IGF1 mRNA]	11985600
C006780	bisphenol A	bisphenol A affects the reaction [CYP19A1 affects the expression of IGF1R mRNA]	11985600
C006780	bisphenol A	[bisphenol A co-treated with Diethylhexyl Phthalate] results in increased expression of CYP19A1 mRNA	22828881
C006780	bisphenol A	[bisphenol A co-treated with Diethylhexyl Phthalate] results in increased expression of CYP19A1 protein	22828881
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 mRNA	21123812\|2118293
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 protein	21123812\|2118293
C006780	bisphenol A	pyrazolanthrone inhibits the reaction [bisphenol A results in increased expression of CYP19A1 mRNA]	28697429
C006780	bisphenol A	pyrazolanthrone inhibits the reaction [bisphenol A results in increased expression of CYP19A1 protein]	28697429
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 mRNA	14595849
C006780	bisphenol A	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C006780	bisphenol A	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C006780	bisphenol A	bisphenol A affects the expression of CYP19A1 mRNA	22285353
C006780	bisphenol A	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CYP19A1 mRNA	25607892
C006780	bisphenol A	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA	25607892
C006780	bisphenol A	bisphenol A inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
C006780	bisphenol A	bisphenol A results in decreased expression of CYP19A1 mRNA	18191889\|2212013
C006780	bisphenol A	[bisphenol A results in decreased expression of CYP19A1 mRNA] which affects the abundance of Estradiol	18191889
C006780	bisphenol A	bisphenol A results in decreased expression of CYP19A1 protein	22285353\|2340523
C006780	bisphenol A	bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein	20096755
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 mRNA	20096755\|2332652
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 protein	20821433\|2406605
C006780	bisphenol A	"[Gonadotropins, Equine co-treated with bisphenol A] results in increased expression of CYP19A1 mRNA"	28648634
C006780	bisphenol A	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C006780	bisphenol A	pyrazolanthrone inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C006780	bisphenol A	SB 239063 inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C006780	bisphenol A	bisphenol A inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]	28284726
C006780	bisphenol A	bisphenol A results in increased expression of CYP19A1 protein	28284726
C005961	bis(tri-n-butyltin)oxide	bisphenol A promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	Chlordecone promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	nonylphenol promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bisphenol A promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein	17599374
C005961	bis(tri-n-butyltin)oxide	Chlordecone promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C005961	bis(tri-n-butyltin)oxide	nonylphenol promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C083642	bitertanol	[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA	23954766
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein	10746939\|1881535
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA	18815356\|2212013
D015124	8-Bromo Cyclic Adenosine Monophosphate	[NR5A1 protein co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA	21610156
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein	21126571\|2212013
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA	23583632
D015124	8-Bromo Cyclic Adenosine Monophosphate	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 protein	21126571
D015124	8-Bromo Cyclic Adenosine Monophosphate	Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
D015124	8-Bromo Cyclic Adenosine Monophosphate	Atrazine promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CYP19A1 mRNA]	23583632
D015124	8-Bromo Cyclic Adenosine Monophosphate	bisphenol A inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
D015124	8-Bromo Cyclic Adenosine Monophosphate	formestane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
D015124	8-Bromo Cyclic Adenosine Monophosphate	Methoxychlor inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
D015124	8-Bromo Cyclic Adenosine Monophosphate	[vinclozolin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA	22120136
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in decreased activity of CYP19A1 protein	27825933
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in decreased expression of CYP19A1 mRNA	29029336
C027561	butylbenzyl phthalate	butylbenzyl phthalate results in decreased expression of CYP19A1 protein	29029336
C027561	butylbenzyl phthalate	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA	29029336
C027561	butylbenzyl phthalate	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein	29029336
C027561	butylbenzyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA	28013214
C038091	butylparaben	butylparaben results in decreased expression of CYP19A1 mRNA	23744433
C038091	butylparaben	butylparaben results in decreased expression of CYP19A1 protein	23744433
C038091	butylparaben	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CYP19A1 mRNA	25607892
C038091	butylparaben	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA	25607892
C038091	butylparaben	butylparaben affects the expression of CYP19A1 protein	26888303
C038091	butylparaben	butylparaben results in decreased expression of CYP19A1 mRNA	27122241
C038091	butylparaben	butylparaben results in increased expression of CYP19A1 mRNA	26888303
D002104	Cadmium	Cadmium results in decreased expression of CYP19A1 mRNA	24376830
D019256	Cadmium Chloride	Cadmium Chloride inhibits the reaction [LHB protein results in increased activity of CYP19A1 protein]	23146792
D019256	Cadmium Chloride	Cadmium Chloride inhibits the reaction [LHB protein results in increased expression of CYP19A1 mRNA]	23146792
D002110	Caffeine	Caffeine results in increased expression of CYP19A1 mRNA	28111094
D002110	Caffeine	Caffeine results in increased expression of CYP19A1 protein	28111094
D000001	Calcimycin	[Calcimycin co-treated with Testosterone] results in decreased activity of CYP19A1 protein	16102761
D000001	Calcimycin	Calcimycin results in decreased activity of CYP19A1 protein	16102761
C010059	carbamylhydrazine	carbamylhydrazine results in increased activity of CYP19A1 protein	19788891
C010059	carbamylhydrazine	[carbamylhydrazine results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone metabolite	19788891
C006698	carbendazim	carbendazim results in increased activity of CYP19A1 protein	14691014
C006698	carbendazim	carbendazim results in increased expression of CYP19A1 mRNA	14691014
D002330	Carmustine	Carmustine results in decreased expression of CYP19A1 mRNA	15980968
D002392	Catechin	Catechin results in decreased activity of CYP19A1 protein	18534843
D000068579	Celecoxib	Celecoxib results in decreased activity of CYP19A1 protein	15964185
D000068579	Celecoxib	Celecoxib results in decreased expression of CYP19A1 mRNA	15964185
D002706	Chlordan	Chlordan inhibits the reaction [Dinoprostone results in increased expression of CYP19A1 mRNA]	20351196
D002706	Chlordan	Chlordan inhibits the reaction [Dinoprostone results in increased expression of CYP19A1 protein]	20351196
D002706	Chlordan	Chlordan results in increased activity of CYP19A1 protein	16996190
D002706	Chlordan	Chlordan results in increased expression of CYP19A1 mRNA	16996190
D007631	Chlordecone	bisphenol A promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	bis(tri-n-butyltin)oxide promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone results in decreased activity of CYP19A1 protein	17599374
D007631	Chlordecone	nonylphenol promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	bisphenol A promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	bis(tri-n-butyltin)oxide promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
D007631	Chlordecone	Chlordecone results in decreased activity of CYP19A1 protein	17599374
D007631	Chlordecone	[Dichlorodiphenyl Dichloroethylene co-treated with Chlordecone] results in increased activity of CYP19A1 protein	17599374
D007631	Chlordecone	nonylphenol promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
D002713	Chlorine	Chlorine results in increased expression of CYP19A1 mRNA	18636392
D002713	Chlorine	[Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA	18636392
D020111	Chlorodiphenyl (54% Chlorine)	[Chlorodiphenyl (54% Chlorine) co-treated with Atrazine] results in decreased activity of CYP19A1 protein	17599374
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased activity of CYP19A1 protein	17599374
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP19A1 mRNA	29208485
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP19A1 protein	29208485
D004390	Chlorpyrifos	[prochloraz co-treated with Chlorpyrifos co-treated with triflusulfuron-methyl] results in increased expression of CYP19A1 mRNA	25233012
C043561	chrysin	chrysin binds to and results in decreased activity of CYP19A1 protein	9435150
C043561	chrysin	chrysin results in decreased activity of CYP19A1 protein	10403137\|1531948
D015283	Citalopram	Citalopram results in decreased activity of CYP19A1 protein	26162595
D003022	Clotrimazole	Clotrimazole results in decreased activity of CYP19A1 protein	15554355
D003022	Clotrimazole	Clotrimazole results in decreased activity of CYP19A1 protein	17081805
D003022	Clotrimazole	Clotrimazole results in decreased expression of CYP19A1 protein	14636634
D003042	Cocaine	Cocaine results in decreased expression of CYP19A1 mRNA	27899881
D003060	Cod Liver Oil	Cod Liver Oil results in decreased expression of CYP19A1 mRNA	26055946
D005576	Colforsin	Colforsin results in increased expression of CYP19A1 mRNA	16641147
D005576	Colforsin	Estradiol promotes the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	16641147
D005576	Colforsin	alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]	16357189
D005576	Colforsin	Aminoglutethimide inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	16935330
D005576	Colforsin	BMP6 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	18936084
D005576	Colforsin	[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA	16357189
D005576	Colforsin	Colforsin results in increased activity of CYP19A1 protein	14691014\|1699619
D005576	Colforsin	[Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Estradiol	20087668
D005576	Colforsin	[Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone	20087668
D005576	Colforsin	Colforsin results in increased expression of CYP19A1 mRNA	14691014\|1635718
D005576	Colforsin	Lindane inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	17080404
D005576	Colforsin	mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	19822197
D005576	Colforsin	NR4A1 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	19822197
D005576	Colforsin	NR4A2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	19822197
D005576	Colforsin	NR4A3 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	19822197
D005576	Colforsin	NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]	16357189
D005576	Colforsin	Valproic Acid inhibits the reaction [Colforsin results in increased activity of CYP19A1 protein]	20726872
D005576	Colforsin	Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	20726872
D005576	Colforsin	ZNF461 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	19822197
D005576	Colforsin	Colforsin results in increased expression of CYP19A1 mRNA	20723554\|2246145
D005576	Colforsin	Colforsin results in increased expression of CYP19A1 protein	22948218
D005576	Colforsin	RARRES2 protein inhibits the reaction [Colforsin results in increased expression of CYP19A1 protein]	22948218
D019327	Copper Sulfate	Copper Sulfate results in decreased expression of CYP19A1 mRNA	19549813
D003484	Cyanamide	Cyanamide inhibits the reaction [CGA protein results in increased expression of CYP19A1 mRNA]	22285649
C057862	cyanoginosin LR	cyanoginosin LR affects the expression of CYP19A1 protein	28189720
D003513	Cycloheximide	Cycloheximide results in decreased activity of CYP19A1 protein	16480277
D003513	Cycloheximide	Cycloheximide results in decreased expression of CYP19A1 protein	21126571
D016572	Cyclosporine	Cyclosporine results in decreased expression of CYP19A1 mRNA	20106945\|2163298
C001765	cyhexatin	cyhexatin results in increased expression of CYP19A1 mRNA	15941851
C017160	cypermethrin	cypermethrin results in increased activity of CYP19A1 protein	16996190
C017160	cypermethrin	cypermethrin results in increased expression of CYP19A1 mRNA	24810582
C017160	cypermethrin	[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA	23954766
C093628	cyproconazole	[prochloraz co-treated with epoxiconazole co-treated with cyproconazole] results in increased expression of CYP19A1 mRNA	25233012
D003534	Cyproterone	[Cyproterone co-treated with Albuterol] results in decreased expression of CYP19A1	17822730
C004742	daidzein	daidzein results in decreased activity of CYP19A1 protein	16023337\|1696591
C004742	daidzein	daidzein results in decreased expression of CYP19A1 mRNA	16965912
C004742	daidzein	[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein	16965912
C004742	daidzein	[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA	16965912
D003634	DDT	DDT results in increased expression of CYP19A1 mRNA	28263910
D003634	DDT	DDT results in decreased expression of CYP19A1 mRNA	12035542
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in increased expression of CYP19A1 protein	28572024
C014347	decitabine	decitabine affects the methylation of CYP19A1 promoter	17662285
D003687	Dehydroepiandrosterone	CYP19A1 protein results in increased metabolism of Dehydroepiandrosterone	16397352
D003687	Dehydroepiandrosterone	Dehydroepiandrosterone results in decreased activity of CYP19A1 protein	10657851
D003687	Dehydroepiandrosterone	Lipopolysaccharides inhibits the reaction [Dehydroepiandrosterone results in decreased activity of CYP19A1 protein]	10657851
C007262	deoxynivalenol	deoxynivalenol results in decreased expression of CYP19A1 mRNA	22982764
C007262	deoxynivalenol	deoxynivalenol inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]	17656051
D003907	Dexamethasone	Calcitriol promotes the reaction [Dexamethasone results in increased activity of CYP19A1 protein]	15862960
D003907	Dexamethasone	Dexamethasone results in decreased expression of CYP19A1 mRNA	25047013
D003907	Dexamethasone	Dexamethasone results in increased activity of CYP19A1 protein	15862960\|1669119
D003907	Dexamethasone	Dexamethasone results in increased expression of CYP19A1 mRNA	15525692\|1669119
D003907	Dexamethasone	Dexamethasone results in decreased expression of CYP19A1	16019206
D003907	Dexamethasone	Dexamethasone results in increased expression of CYP19A1	16019206
C020735	dibutyldichlorotin	dibutyldichlorotin results in decreased activity of CYP19A1 protein	11522339
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased activity of CYP19A1 protein	27825933
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of CYP19A1 mRNA	28104404
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of CYP19A1 mRNA	29029336
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of CYP19A1 mRNA	25765776
D003993	Dibutyl Phthalate	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA	29029336
D003993	Dibutyl Phthalate	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein	29029336
D003993	Dibutyl Phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA	28013214
D003993	Dibutyl Phthalate	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in increased expression of CYP19A1 mRNA	19560483
D003996	Dicamba	Dicamba results in decreased expression of CYP19A1 mRNA	24420721
D003633	Dichlorodiphenyl Dichloroethylene	[Dichlorodiphenyl Dichloroethylene co-treated with bisphenol A] results in decreased activity of CYP19A1 protein	17599374
D003633	Dichlorodiphenyl Dichloroethylene	[Dichlorodiphenyl Dichloroethylene co-treated with Chlordecone] results in increased activity of CYP19A1 protein	17599374
D003633	Dichlorodiphenyl Dichloroethylene	[Dichlorodiphenyl Dichloroethylene co-treated with FSHB protein] results in increased activity of CYP19A1 protein	15070871
D003633	Dichlorodiphenyl Dichloroethylene	[Dichlorodiphenyl Dichloroethylene co-treated with nonylphenol] results in increased activity of CYP19A1 protein	17599374
D003633	Dichlorodiphenyl Dichloroethylene	"[Dichlorodiphenyl Dichloroethylene co-treated with o,p'-DDT] results in decreased activity of CYP19A1 protein"	17599374
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased activity of CYP19A1 protein	17599374
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased activity of CYP19A1 protein	15070871
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of and results in increased activity of CYP19A1 protein	16077170
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of CYP19A1 mRNA	20924025
D003633	Dichlorodiphenyl Dichloroethylene	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased expression of CYP19A1 mRNA	12035542
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased activity of CYP19A1 protein	18195494
D004010	Dicofol	Dicofol results in decreased activity of CYP19A1 protein	10806373
C000944	dicrotophos	dicrotophos results in decreased expression of CYP19A1 mRNA	28302478
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate results in increased expression of CYP19A1 mRNA	26924002
C023635	dienogest	dienogest results in decreased expression of CYP19A1 mRNA	22130322
C023635	dienogest	dienogest results in decreased expression of CYP19A1 protein	22130322
D004041	Dietary Fats	Dietary Fats results in increased activity of CYP19A1 protein	23880231
D004041	Dietary Fats	Dietary Fats results in increased expression of CYP19A1 mRNA	23880231
D004041	Dietary Fats	Zyflamend inhibits the reaction [Dietary Fats results in increased activity of CYP19A1 protein]	23880231
D004041	Dietary Fats	Zyflamend inhibits the reaction [Dietary Fats results in increased expression of CYP19A1 mRNA]	23880231
D004051	Diethylhexyl Phthalate	[bisphenol A co-treated with Diethylhexyl Phthalate] results in increased expression of CYP19A1 mRNA	22828881
D004051	Diethylhexyl Phthalate	[bisphenol A co-treated with Diethylhexyl Phthalate] results in increased expression of CYP19A1 protein	22828881
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate affects the expression of CYP19A1 mRNA	25701202
D004051	Diethylhexyl Phthalate	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA	29029336
D004051	Diethylhexyl Phthalate	[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein	29029336
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of CYP19A1 mRNA	19874833\|2828611
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of CYP19A1 mRNA	27405655
D004051	Diethylhexyl Phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA	28013214
D004051	Diethylhexyl Phthalate	[Benzo(a)pyrene co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP19A1 mRNA	20920559
D004051	Diethylhexyl Phthalate	[Benzo(a)pyrene co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP19A1 protein	20920559
D004051	Diethylhexyl Phthalate	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate affects the expression of CYP19A1 mRNA	20568448
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased activity of CYP19A1 protein	16949715
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of CYP19A1 mRNA	20920559\|2887146
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of CYP19A1 protein	20920559
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased activity of CYP19A1 protein	16949715
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of CYP19A1 mRNA	16763069\|1956048
C007379	diethyl phthalate	diethyl phthalate promotes the reaction [ESR1 protein binds to CYP19A1 promoter]	24994688
C007379	diethyl phthalate	diethyl phthalate results in increased expression of CYP19A1 protein	24994688
C007379	diethyl phthalate	Tamoxifen inhibits the reaction [diethyl phthalate promotes the reaction [ESR1 protein binds to CYP19A1 promoter]]	24994688
C007379	diethyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA	28013214
C007379	diethyl phthalate	diethyl phthalate results in increased expression of CYP19A1 mRNA	24994688
C007379	diethyl phthalate	diethyl phthalate results in increased expression of CYP19A1 protein	24994688
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased activity of CYP19A1 protein	17599374
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CYP19A1 mRNA	22100434\|2897013
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]	15878960
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CYP19A1 mRNA	15525594
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of CYP19A1 protein	15525594
C115058	difenoconazole	difenoconazole results in decreased activity of CYP19A1 protein	17081805
D002117	Calcitriol	Calcitriol promotes the reaction [Dexamethasone results in increased activity of CYP19A1 protein]	15862960
D002117	Calcitriol	Calcitriol results in increased activity of CYP19A1 protein	15862960
D002117	Calcitriol	Calcitriol results in increased expression of CYP19A1 mRNA	16002434
C025605	diisobutyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA	28013214
C012125	diisononyl phthalate	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CYP19A1 mRNA	28013214
D004117	Dimethoate	Dimethoate results in increased expression of CYP19A1 mRNA	23943137
C056189	di-n-butyltin	di-n-butyltin analog results in decreased activity of CYP19A1 protein	11751016
C034171	di-n-pentyl phthalate	di-n-pentyl phthalate results in increased expression of CYP19A1 mRNA	19560483
C086664	diphenyltin chloride	diphenyltin chloride results in increased expression of CYP19A1 mRNA	15941851
D004221	Disulfiram	Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	22285649
C067311	docetaxel	docetaxel results in decreased expression of CYP19A1 mRNA	15623590
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased expression of CYP19A1 mRNA"	14711788
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in increased expression of CYP19A1 protein"	14711788
D004365	Drugs, Chinese Herbal	"Drugs, Chinese Herbal results in decreased activity of CYP19A1 protein"	17895526
C063968	E 4031	CYP19A1 gene mutant form results in decreased susceptibility to E 4031	25972195
C046770	EGTA acetoxymethyl ester	EGTA acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D052244	Endocrine Disruptors	Endocrine Disruptors results in decreased expression of CYP19A1 mRNA	29029336
D004726	Endosulfan	Endosulfan results in increased activity of CYP19A1 protein	16996190
C017435	enilconazole	enilconazole results in decreased activity of CYP19A1 protein	10806373\|1555435
C017435	enilconazole	enilconazole results in decreased activity of CYP19A1 protein	17081805
C100264	enniatins	enniatins results in increased expression of CYP19A1 mRNA	25625232
D004785	Environmental Pollutants	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
C038939	enzacamene	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CYP19A1 mRNA	25607892
C038939	enzacamene	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA	25607892
C045651	epigallocatechin gallate	epigallocatechin gallate results in decreased activity of CYP19A1 protein	14600287
C046855	epostane	[epostane co-treated with Dinoprost] results in increased expression of CYP19A1 mRNA	20739670
C109476	epoxiconazole	[prochloraz co-treated with epoxiconazole co-treated with cyproconazole] results in increased expression of CYP19A1 mRNA	25233012
C109476	epoxiconazole	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
D060754	Equol	Equol results in decreased expression of CYP19A1 mRNA	26876617
D000069347	Erlotinib Hydrochloride	Erlotinib Hydrochloride results in decreased activity of CYP19A1 protein	26141389
D004923	Erythrosine	Erythrosine results in decreased activity of CYP19A1 protein	18310892
C074283	estradiol 3-benzoate	CYP19A1 protein affects the susceptibility to estradiol 3-benzoate	16884724
D004964	Estriol	Estriol inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134
D004964	Estriol	Estriol results in decreased expression of CYP19A1 mRNA	21296134
D004967	Estrogens	CYP19A1 protein affects the chemical synthesis of Estrogens	12839940\|1602094
D004967	Estrogens	CYP19A1 protein results in increased chemical synthesis of Estrogens	15623590\|1639735
D004967	Estrogens	Estrogens analog binds to and results in decreased activity of CYP19A1 protein	16039845
D004967	Estrogens	CYP19A1 protein affects the chemical synthesis of Estrogens	16019206
D004967	Estrogens	Estrogens affects the expression of CYP19A1	16019206
D004967	Estrogens	CYP19A1 protein results in increased chemical synthesis of Estrogens	14684609
D004967	Estrogens	CYP19A1 protein affects the chemical synthesis of Estrogens	16080194
D004967	Estrogens	Aromatase Inhibitors inhibits the reaction [CYP19A1 protein affects the chemical synthesis of Estrogens]	15992333
D004967	Estrogens	CYP19A1 protein affects the chemical synthesis of Estrogens	14580722\|1598363
D004967	Estrogens	CYP19A1 protein results in increased chemical synthesis of Estrogens	21854827
D004967	Estrogens	[CYP19A1 protein results in increased metabolism of Androgens] which results in increased chemical synthesis of Estrogens	10814527
D004967	Estrogens	IL1B protein promotes the reaction [CYP19A1 protein affects the chemical synthesis of Estrogens]	15983630
D004967	Estrogens	IL6 protein promotes the reaction [CYP19A1 protein affects the chemical synthesis of Estrogens]	15983630
D004967	Estrogens	TNF protein promotes the reaction [CYP19A1 protein affects the chemical synthesis of Estrogens]	15983630
D004967	Estrogens	[troglitazone results in decreased activity of CYP19A1 protein] inhibits the reaction [[CYP19A1 protein results in increased metabolism of Androgens] which results in increased chemical synthesis of Estrogens]	10814527
D004970	Estrone	CYP19A1 protein affects the chemical synthesis of Estrone	12568797
D004970	Estrone	CYP19A1 protein affects the chemical synthesis of Estrone	16030167
D004970	Estrone	CYP19A1 protein results in increased chemical synthesis of Estrone	16054388
D004970	Estrone	Estrone analog binds to and results in decreased activity of CYP19A1 protein	16039845
D004970	Estrone	TNF protein promotes the reaction [CYP19A1 protein affects the chemical synthesis of Estrone]	16030167
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of CYP19A1 mRNA	16954407
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the activity of CYP19A1 protein	15719995
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of CYP19A1 mRNA	23300682
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of CYP19A1 mRNA	28522409
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of CYP19A1 protein	28522409
D004997	Ethinyl Estradiol	[Ethinyl Estradiol co-treated with tributyltin] affects the activity of CYP19A1 protein	16484284
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased activity of CYP19A1 protein	16484284
D005013	Ethosuximide	Ethosuximide results in decreased activity of CYP19A1 protein	17959350
C026098	etiracetam	etiracetam results in decreased expression of CYP19A1 mRNA	19566492
C056516	exemestane	exemestane results in decreased activity of CYP19A1 protein	15837728\|1590981
D015025	Zearalenone	Zearalenone results in decreased activity of CYP19A1 protein	16023337
D015025	Zearalenone	Zearalenone inhibits the reaction [[FSHB protein co-treated with IGF1 protein] results in increased expression of CYP19A1 mRNA]	17656051
D017316	Fadrozole	Fadrozole results in decreased activity of CYP19A1 protein	12568797
D017316	Fadrozole	Fadrozole results in decreased activity of CYP19A1 protein	1659868
D017316	Fadrozole	Fadrozole results in decreased activity of CYP19A1 protein	15743198\|1577142
D017316	Fadrozole	Fadrozole results in increased activity of CYP19A1 protein	21854827
D017316	Fadrozole	Genistein inhibits the reaction [Fadrozole results in increased activity of CYP19A1 protein]	21854827
D017316	Fadrozole	Fadrozole results in decreased activity of CYP19A1 protein	14981786
D017316	Fadrozole	"Fadrozole inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of and results in increased activity of CYP19A1 protein]"	23146758
D017316	Fadrozole	Fadrozole results in decreased activity of CYP19A1 protein	15985365
D005204	Farnesol	Farnesol results in increased activity of CYP19A1 protein	15840382
C033789	fenarimol	fenarimol results in decreased activity of CYP19A1 protein	10806373\|1188423
C033789	fenarimol	fenarimol results in increased expression of CYP19A1 mRNA	21722721
C033789	fenarimol	fenarimol results in increased expression of CYP19A1 protein	21722721
C033789	fenarimol	fenarimol results in decreased activity of CYP19A1 protein	17081805
C033789	fenarimol	fenarimol results in decreased activity of CYP19A1 protein	16324804
C504383	fenbuconazole	fenbuconazole results in decreased activity of CYP19A1 protein	16996190
C504383	fenbuconazole	fenbuconazole results in decreased activity of CYP19A1 protein	17081805
D018120	Finasteride	[Finasteride co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	23523586
D018120	Finasteride	Finasteride promotes the reaction [[tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	23523586
D018120	Finasteride	tributyltin promotes the reaction [[Finasteride co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	23523586
D018120	Finasteride	Finasteride promotes the reaction [Androstenedione results in increased expression of CYP19A1 mRNA]	21273442
D018120	Finasteride	Finasteride promotes the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	21273442
C111409	finrozole	finrozole inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134\|2340293
C111409	finrozole	[finrozole inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]] which results in decreased chemical synthesis of aflatoxicol	21296134
C111409	finrozole	finrozole results in decreased activity of CYP19A1 protein	15781295
D005411	Flame Retardants	Flame Retardants metabolite results in decreased activity of CYP19A1 protein	18022659
D005411	Flame Retardants	Flame Retardants metabolite results in decreased expression of CYP19A1 mRNA	18248924
D005411	Flame Retardants	Flame Retardants metabolite results in increased expression of CYP19A1 mRNA	18248924
D005411	Flame Retardants	Flame Retardants results in increased expression of CYP19A1 mRNA	17447562\|2244682
D044950	Flavanones	Flavanones results in decreased activity of CYP19A1 protein	17910019
C043562	flavone	flavone results in increased activity of CYP19A1 protein	15319488
D047309	Flavones	Flavones results in decreased activity of CYP19A1 protein	17910019
D005419	Flavonoids	Flavonoids analog results in decreased activity of CYP19A1 protein	15319488
D005419	Flavonoids	Flavonoids results in decreased expression of CYP19A1 mRNA	18035473
D005473	Fluoxetine	Fluoxetine results in decreased activity of CYP19A1 protein	26162595
C061365	flusilazole	flusilazole results in decreased activity of CYP19A1 protein	15554355
D005485	Flutamide	Flutamide results in increased expression of CYP19A1 mRNA	26485406
D016666	Fluvoxamine	Fluvoxamine results in decreased activity of CYP19A1 protein	26162595
D005520	Food Preservatives	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
C014594	formestane	formestane inhibits the reaction [Atrazine results in increased activity of CYP19A1 protein]	10746939
C014594	formestane	"formestane inhibits the reaction [CYP19A1 protein affects the chemical synthesis of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine]"	15242824
C014594	formestane	formestane inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]	15242824
C014594	formestane	formestane inhibits the reaction [propazine results in increased activity of CYP19A1 protein]	10746939
C014594	formestane	formestane inhibits the reaction [Simazine results in increased activity of CYP19A1 protein]	10746939
C014594	formestane	formestane results in decreased activity of CYP19A1 protein	10806373\|1531948
C014594	formestane	formestane results in decreased activity of CYP19A1 protein	15964245
C014594	formestane	formestane results in decreased activity of CYP19A1 protein	17081805
C014594	formestane	formestane inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
C014594	formestane	formestane inhibits the reaction [FSHB protein results in increased activity of CYP19A1 protein]	22120136
C014594	formestane	formestane promotes the reaction [Androstenedione results in increased expression of CYP19A1 mRNA]	21273442
C014594	formestane	formestane promotes the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	21273442
C014594	formestane	formestane results in decreased activity of CYP19A1 protein	17895526\|2112657
C014594	formestane	formestane results in decreased activity of CYP19A1 protein	14602803
C070081	fulvestrant	fulvestrant inhibits the reaction [Estradiol results in increased expression of CYP19A1 mRNA]	16641147
C070081	fulvestrant	fulvestrant inhibits the reaction [[Testosterone co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA]	16641147
C070081	fulvestrant	fulvestrant inhibits the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	16641147
C070081	fulvestrant	fulvestrant results in decreased expression of CYP19A1 mRNA	16641147
C070081	fulvestrant	fulvestrant results in decreased activity of CYP19A1 protein	11850205\|1597655
D005659	Fungicides, Industrial	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
D005707	Gallic Acid	Gallic Acid results in decreased activity of CYP19A1 protein	18310892
D019833	Genistein	[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein	16965912
D019833	Genistein	[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA	16965912
D019833	Genistein	Genistein inhibits the reaction [Fadrozole results in increased activity of CYP19A1 protein]	21854827
D019833	Genistein	Genistein results in decreased activity of CYP19A1 protein	15876411\|1602333
D019833	Genistein	Genistein results in decreased expression of CYP19A1 mRNA	16965912
D019833	Genistein	Genistein results in increased activity of CYP19A1 protein	15319488
D019833	Genistein	Genistein results in increased expression of CYP19A1 mRNA	15319488\|1954992
D019833	Genistein	Genistein results in increased expression of CYP19A1 protein	21854827
D019833	Genistein	[Genistein co-treated with Methoxychlor] results in decreased expression of CYP19A1 mRNA	21782745
D019833	Genistein	Genistein results in decreased expression of CYP19A1 mRNA	12035542
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in decreased expression of and results in decreased activity of CYP19A1 protein	26706698
C063170	Ginkgo biloba extract	Ginkgo biloba extract results in decreased expression of CYP19A1 mRNA	26706698
C010974	glyphosate	glyphosate results in increased expression of CYP19A1 mRNA	24364672
C010974	glyphosate	glyphosate binds to CYP19A1 protein	15929894
C010974	glyphosate	[glyphosate co-treated with Herbicides] affects the activity of CYP19A1 protein	19539684
C010974	glyphosate	[glyphosate co-treated with Herbicides] affects the expression of CYP19A1 mRNA	19539684
C010974	glyphosate	glyphosate results in decreased activity of CYP19A1 protein	15929894\|1748628
C010974	glyphosate	glyphosate results in decreased expression of CYP19A1 mRNA	15929894
C010974	glyphosate	glyphosate results in increased expression of CYP19A1 mRNA	24930125
C010974	glyphosate	glyphosate results in increased expression of CYP19A1 protein	24930125
D012739	Gonadal Steroid Hormones	CYP19A1 protein affects the chemical synthesis of Gonadal Steroid Hormones	16045239
D006064	Gonadotropins, Equine	"[Gonadotropins, Equine co-treated with bisphenol A] results in increased expression of CYP19A1 mRNA"	28648634
D006064	Gonadotropins, Equine	"Gonadotropins, Equine inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 mRNA]"	19276399
C511402	Grape Seed Proanthocyanidins	Grape Seed Proanthocyanidins results in decreased activity of CYP19A1 protein	18534843
D055768	Halogenated Diphenyl Ethers	Halogenated Diphenyl Ethers metabolite results in decreased activity of CYP19A1 protein	18022659
D055768	Halogenated Diphenyl Ethers	Halogenated Diphenyl Ethers metabolite results in increased expression of CYP19A1 mRNA	18248924\|1831309
C571106	halowax 1051	halowax 1051 inhibits the reaction [ADIPOQ protein results in increased expression of CYP19A1 protein]	28284726
C571106	halowax 1051	halowax 1051 results in decreased activity of CYP19A1 protein	22001251
C571106	halowax 1051	halowax 1051 results in decreased expression of CYP19A1 protein	22001251
C571106	halowax 1051	halowax 1051 results in increased activity of CYP19A1 protein	22001251
C571106	halowax 1051	halowax 1051 results in increased expression of CYP19A1 protein	22001251
D015386	Hazardous Substances	Hazardous Substances results in decreased activity of CYP19A1 protein	10667936
D006063	Chorionic Gonadotropin	Atrazine inhibits the reaction [Chorionic Gonadotropin results in increased expression of CYP19A1 mRNA]	26923738
D006063	Chorionic Gonadotropin	Chorionic Gonadotropin results in increased expression of CYP19A1 mRNA	26923738
D006533	Heptachlor	Heptachlor results in decreased activity of CYP19A1 protein	16996190
D006540	Herbicides	[glyphosate co-treated with Herbicides] affects the activity of CYP19A1 protein	19539684
D006540	Herbicides	[glyphosate co-treated with Herbicides] affects the expression of CYP19A1 mRNA	19539684
D006540	Herbicides	Herbicides binds to CYP19A1 protein	15929894
D006540	Herbicides	Herbicides results in decreased activity of CYP19A1 protein	15929894\|1748628
D006540	Herbicides	Herbicides results in decreased expression of CYP19A1 mRNA	15929894
D006540	Herbicides	Herbicides results in increased expression of CYP19A1 mRNA	24930125
D006540	Herbicides	Herbicides results in increased expression of CYP19A1 protein	24930125
D006540	Herbicides	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
C013015	hesperetin	hesperetin results in decreased activity of CYP19A1 protein	10403137
C089796	hexabromocyclododecane	hexabromocyclododecane results in increased expression of CYP19A1 mRNA	25765474
C089796	hexabromocyclododecane	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
D006581	Hexachlorobenzene	Hexachlorobenzene results in decreased expression of CYP19A1 protein	21296658
C409722	hexaconazole	hexaconazole results in decreased activity of CYP19A1 protein	12127262
C012351	HT-2 toxin	HT-2 toxin results in decreased expression of CYP19A1 mRNA	22982764
D007052	Ibuprofen	Ibuprofen results in decreased activity of CYP19A1 protein	15964185
D007052	Ibuprofen	Ibuprofen results in decreased expression of CYP19A1 mRNA	15964185
C082359	imidacloprid	imidacloprid results in increased activity of CYP19A1 protein	28750898
C011582	IMOL S-140	IMOL S-140 results in increased expression of CYP19A1 mRNA	22446829
D007189	Indans	Indans results in decreased activity of CYP19A1 protein	15743198
C027185	indirubin	indirubin results in increased expression of CYP19A1 mRNA	15056799
D007213	Indomethacin	Indomethacin results in decreased activity of CYP19A1 protein	15964185
D007213	Indomethacin	Indomethacin results in decreased expression of CYP19A1 mRNA	15964185
D007213	Indomethacin	Indomethacin results in increased expression of CYP19A1 mRNA	18299717
D007220	Industrial Waste	Industrial Waste results in decreased expression of CYP19A1 mRNA	26055946
D007306	Insecticides	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
D015759	Ionomycin	[Ionomycin co-treated with Testosterone] results in decreased activity of CYP19A1 protein	16102761
C033148	iprodione	iprodione results in increased activity of CYP19A1 protein	11884232
C040920	isoliquiritigenin	isoliquiritigenin results in decreased expression of CYP19A1 mRNA	27773742
C514852	isopropyl thioxanthone	isopropyl thioxanthone analog results in increased activity of CYP19A1 protein	23208609
C514852	isopropyl thioxanthone	isopropyl thioxanthone analog results in increased expression of CYP19A1 mRNA	23208609
D007654	Ketoconazole	Ketoconazole results in decreased activity of CYP19A1 protein	27159630
D007654	Ketoconazole	Ketoconazole results in increased activity of CYP19A1 protein	20087668
D007654	Ketoconazole	Ketoconazole results in decreased activity of CYP19A1 protein	20087668
C047781	lamotrigine	lamotrigine results in decreased activity of CYP19A1 protein	17959350
C045463	leflunomide	leflunomide results in increased expression of CYP19A1 mRNA	28988120
C067431	letrozole	letrozole inhibits the reaction [sodium arsenite results in increased expression of CYP19A1 mRNA]	24068038
C067431	letrozole	letrozole results in decreased activity of CYP19A1 protein	15837728\|1590981
C067431	letrozole	letrozole results in increased activity of CYP19A1 protein	20087668
C067431	letrozole	letrozole results in decreased activity of CYP19A1 protein	15967659
C067431	letrozole	letrozole binds to and results in decreased activity of CYP19A1 protein	24902786
C067431	letrozole	letrozole results in decreased activity of CYP19A1 protein	16020964\|2008766
D016729	Leuprolide	[Leuprolide co-treated with Testosterone] results in decreased expression of CYP19A1 mRNA	16032706
C095104	LG 100268	[LG 100268 binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein	15941851
C095104	LG 100268	LG 100268 promotes the reaction [troglitazone results in decreased activity of CYP19A1 mRNA]	10814527
C095104	LG 100268	LG 100268 promotes the reaction [troglitazone results in decreased activity of CYP19A1 protein]	10814527
C095104	LG 100268	LG 100268 results in decreased activity of CYP19A1 protein	10814527
C095104	LG 100268	LG 100268 results in decreased expression of CYP19A1 mRNA	10814527
C095104	LG 100268	LG 100268 results in increased expression of CYP19A1 mRNA	15941851
C095104	LG 100268	troglitazone promotes the reaction [LG 100268 results in decreased activity of CYP19A1 mRNA]	10814527
C095104	LG 100268	troglitazone promotes the reaction [LG 100268 results in decreased activity of CYP19A1 protein]	10814527
C061121	liarozole	liarozole results in decreased activity of CYP19A1 protein	21838328
D001556	Lindane	Lindane inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	17080404
D001556	Lindane	Lindane results in decreased activity of CYP19A1 protein	12849724
D001556	Lindane	Lindane results in increased activity of CYP19A1 protein	12849724
D001556	Lindane	Lindane results in increased expression of CYP19A1 mRNA	17080404
D008044	Linuron	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
D008070	Lipopolysaccharides	Lipopolysaccharides promotes the reaction [CEBPB protein binds to CYP19A1 promoter]	28412504
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of CYP19A1 mRNA	28412504
D008070	Lipopolysaccharides	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [Lipopolysaccharides promotes the reaction [CEBPB protein binds to CYP19A1 promoter]]	28412504
D008070	Lipopolysaccharides	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP19A1 mRNA]	28412504
D008070	Lipopolysaccharides	Lipopolysaccharides inhibits the reaction [Dehydroepiandrosterone results in decreased activity of CYP19A1 protein]	10657851
D008294	Malathion	[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA	23954766
D008550	Melatonin	Melatonin results in decreased expression of CYP19A1	16080194
D008550	Melatonin	Melatonin results in decreased activity of CYP19A1 protein	16080194
D008687	Metformin	Metformin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 protein]	16760380
D008691	Methadone	Aminoglutethimide inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]	15242824
D008691	Methadone	CYP19A1 protein affects the metabolism of Methadone	15242824
D008691	Methadone	formestane inhibits the reaction [CYP19A1 protein affects the metabolism of Methadone]	15242824
D008724	Methomyl	Methomyl results in increased activity of CYP19A1 protein	11884232
D008727	Methotrexate	Methotrexate results in increased expression of CYP19A1 mRNA	17400583
D008727	Methotrexate	Methotrexate affects the expression of CYP19A1 mRNA	18502557
D008731	Methoxychlor	Methoxychlor affects the expression of CYP19A1 mRNA	22120136
D008731	Methoxychlor	Methoxychlor affects the reaction [CYP19A1 protein results in increased metabolism of Androstenedione]	22120136
D008731	Methoxychlor	Methoxychlor results in increased activity of CYP19A1 protein	16996190
D008731	Methoxychlor	Methoxychlor results in increased expression of CYP19A1 mRNA	16996190
D008731	Methoxychlor	Methoxychlor results in decreased expression of CYP19A1 mRNA	21514315
D008731	Methoxychlor	Methoxychlor results in increased expression of CYP19A1 mRNA	25048109
D008731	Methoxychlor	[Genistein co-treated with Methoxychlor] results in decreased expression of CYP19A1 mRNA	21782745
D008731	Methoxychlor	Methoxychlor affects the expression of CYP19A1 mRNA	22120136\|2228535
D008731	Methoxychlor	Methoxychlor inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of CYP19A1 protein]	22120136
D008731	Methoxychlor	Methoxychlor metabolite inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]	16737795
D008731	Methoxychlor	Methoxychlor metabolite results in decreased activity of CYP19A1 protein	23326527
D008731	Methoxychlor	Methoxychlor results in decreased expression of CYP19A1 protein	22285353
C104810	methyl arachidonylfluorophosphonate	methyl arachidonylfluorophosphonate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
C004925	methylmercuric chloride	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
D008767	Methylmercury Compounds	Methylmercury Compounds results in decreased activity of CYP19A1 protein	17081805
C015358	methylparaben	methylparaben affects the expression of CYP19A1 mRNA	23744433
C015358	methylparaben	methylparaben affects the expression of CYP19A1 protein	23744433
D008743	Methyl Parathion	Methyl Parathion results in increased activity of CYP19A1 protein	16996190
D008777	Methyltestosterone	Methyltestosterone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
C051786	metolachlor	metolachlor results in increased activity of CYP19A1 protein	16996190
D008825	Miconazole	Miconazole results in decreased activity of CYP19A1 protein	15554355
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	19822197
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in decreased activity of CYP19A1 protein	19501113
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA	19501113\|2240184
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA	19874833\|2240184
C016599	mono-(2-ethylhexyl)phthalate	alitretinoin promotes the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA]	12706301
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in decreased expression of CYP19A1 mRNA	12706301
D008999	Monocrotophos	Monocrotophos results in increased expression of CYP19A1 mRNA	20149464
D009183	Mycotoxins	Mycotoxins results in increased expression of CYP19A1 mRNA	23665424
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Testosterone co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA]	16641147
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	"N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	"N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Water Pollutants, Chemical analog results in increased expression of CYP19A1 mRNA]"	21932247
C063509	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide analog results in decreased activity of CYP19A1 protein	16480277
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide analog results in decreased expression of CYP19A1 mRNA	16480277
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]	28571770
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]"	20678559
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of CYP19A1 protein	15964185\|1648027
C080955	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide	N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP19A1 mRNA	15964185\|1648027
C031721	naphthalene	[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of CYP19A1 protein	28803881
C031721	naphthalene	naphthalene results in increased expression of CYP19A1 protein	28803881
D009281	Naphthalenes	Naphthalenes analog results in decreased activity of CYP19A1 protein	15449729
C005273	naringenin	naringenin binds to and results in decreased activity of CYP19A1 protein	9435150
C005273	naringenin	naringenin results in decreased activity of CYP19A1 protein	15319488
C005273	naringenin	naringenin results in decreased activity of CYP19A1 protein	17895526
D009544	Niflumic Acid	Niflumic Acid results in decreased activity of CYP19A1 protein	15964185
D009544	Niflumic Acid	Niflumic Acid results in decreased expression of CYP19A1 mRNA	15964185
C012655	nimesulide	nimesulide analog results in decreased activity of and results in decreased expression of CYP19A1	17315855
C012655	nimesulide	nimesulide analog results in decreased activity of CYP19A1 protein	20542113
C012655	nimesulide	nimesulide analog results in decreased expression of CYP19A1 mRNA	20542113
C012655	nimesulide	nimesulide results in decreased activity of CYP19A1	17315855
C012655	nimesulide	nimesulide results in decreased activity of CYP19A1 protein	15964185
C012655	nimesulide	nimesulide results in decreased expression of CYP19A1 mRNA	15964185
C012655	nimesulide	nimesulide results in decreased activity of CYP19A1 protein	23054057
C012655	nimesulide	nimesulide analog results in decreased activity of CYP19A1 protein	18271519
C012655	nimesulide	nimesulide analog results in decreased expression of CYP19A1	18271519
C012655	nimesulide	nimesulide results in decreased activity of and results in decreased expression of CYP19A1 protein	20542113
C012655	nimesulide	nimesulide results in decreased activity of CYP19A1 protein	18271519
C012655	nimesulide	nimesulide results in decreased expression of CYP19A1	18271519
C574385	N,N-didesmethyl-4-hydroxytamoxifen	"CYP19A1 protein results in increased metabolism of N,N-didesmethyl-4-hydroxytamoxifen"	29285606
C574385	N,N-didesmethyl-4-hydroxytamoxifen	"[CYP19A1 protein results in increased metabolism of N,N-didesmethyl-4-hydroxytamoxifen] which results in increased abundance of N,N-didesmethyl-4-hydroxytamoxifen"	29285606
C025256	nonylphenol	bisphenol A promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	bis(tri-n-butyltin)oxide promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	Chlordecone promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol results in decreased activity of CYP19A1 protein	17599374
C025256	nonylphenol	bisphenol A promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	bis(tri-n-butyltin)oxide promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	Chlordecone promotes the reaction [nonylphenol results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	[Dichlorodiphenyl Dichloroethylene co-treated with nonylphenol] results in increased activity of CYP19A1 protein	17599374
C025256	nonylphenol	nonylphenol promotes the reaction [bisphenol A results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol promotes the reaction [bis(tri-n-butyltin)oxide results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol promotes the reaction [Chlordecone results in decreased activity of CYP19A1 protein]	17599374
C025256	nonylphenol	nonylphenol results in decreased activity of CYP19A1 protein	17599374
C025256	nonylphenol	nonylphenol results in increased activity of CYP19A1 protein	27825933
C025256	nonylphenol	nonylphenol results in increased expression of CYP19A1 mRNA	14595849
D016912	Levonorgestrel	Levonorgestrel results in decreased expression of CYP19A1 mRNA	21914719
D009277	Nandrolone	Nandrolone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
C464660	obeticholic acid	obeticholic acid results in decreased expression of CYP19A1 mRNA	27939613
C025589	ochratoxin A	ochratoxin A results in increased expression of CYP19A1 protein	23296098
C118580	octylmethoxycinnamate	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] affects the expression of CYP19A1 mRNA	25607892
C118580	octylmethoxycinnamate	[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CYP19A1 mRNA	25607892
C474055	octylphenol	octylphenol results in increased activity of CYP19A1 protein	27825933
C002769	oleuropein	oleuropein results in decreased activity of CYP19A1 protein	17910019
C016340	o,p'-DDT	"2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]"	20678559
C016340	o,p'-DDT	"6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]"	20678559
C016340	o,p'-DDT	"AH 23848 inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"[alpha-naphthoflavone results in decreased activity of CYP19A1 protein] which results in decreased susceptibility to o,p'-DDT"	20678559
C016340	o,p'-DDT	"[Dichlorodiphenyl Dichloroethylene co-treated with o,p'-DDT] results in decreased activity of CYP19A1 protein"	17599374
C016340	o,p'-DDT	"N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 mRNA]"	20678559
C016340	o,p'-DDT	"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"[o,p'-DDT co-treated with Atrazine] results in increased activity of CYP19A1 protein"	17599374
C016340	o,p'-DDT	"o,p'-DDT results in decreased activity of CYP19A1 protein"	17599374
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of CYP19A1 mRNA"	20678559
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of CYP19A1 protein"	20678559
C016340	o,p'-DDT	"pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C016340	o,p'-DDT	"[vinclozolin co-treated with o,p'-DDT] results in decreased activity of CYP19A1 protein"	17599374
C016340	o,p'-DDT	"o,p'-DDT results in decreased expression of CYP19A1 mRNA"	28263910
C016340	o,p'-DDT	"o,p'-DDT results in increased activity of CYP19A1 protein"	18195494
C012466	oxadiazon	oxadiazon results in increased activity of CYP19A1 protein	16996190
C036006	oxcarbazepine	oxcarbazepine results in decreased activity of CYP19A1 protein	17959350
C022155	oxiconazole	oxiconazole results in decreased activity of CYP19A1 protein	24496634
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [Lipopolysaccharides promotes the reaction [CEBPB protein binds to CYP19A1 promoter]]	28412504
C472349	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine	oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP19A1 mRNA]	28412504
D010126	Ozone	[Ozone co-treated with Chlorine] affects the expression of CYP19A1 mRNA	18636392
D017239	Paclitaxel	Paclitaxel results in increased activity of CYP19A1 protein	14691014
D017374	Paroxetine	Paroxetine results in decreased activity of CYP19A1 protein	26162595
C517782	pasireotide	pasireotide inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]	23137853
C098189	pentabromophenol	pentabromophenol results in increased expression of CYP19A1 mRNA	17447562
C003060	pentachlorobenzene	pentachlorobenzene results in increased expression of CYP19A1 protein	21296658
D010416	Pentachlorophenol	Pentachlorophenol results in decreased expression of CYP19A1 mRNA	21296122
C003072	perflubron	perflubron results in increased expression of CYP19A1 mRNA	25871633
C584865	perfluorononanoic acid	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid results in increased expression of CYP19A1 mRNA	23074026\|2576547
C076994	perfluorooctane sulfonic acid	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
C076994	perfluorooctane sulfonic acid	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP19A1 mRNA"	25765474
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased expression of CYP19A1 mRNA	23399300
C023036	perfluorooctanoic acid	[perfluorooctanoic acid co-treated with PPARA] results in increased expression of CYP19A1 mRNA	20118188
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased activity of CYP19A1 protein	8812269
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in increased activity of CYP19A1 protein	8812269
D015232	Dinoprostone	2-methoxyoestrone-3-O-sulphamate inhibits the reaction [Dinoprostone results in increased activity of CYP19A1 protein]	15862962
D015232	Dinoprostone	Chlordan inhibits the reaction [Dinoprostone results in increased expression of CYP19A1 mRNA]	20351196
D015232	Dinoprostone	Chlordan inhibits the reaction [Dinoprostone results in increased expression of CYP19A1 protein]	20351196
D015232	Dinoprostone	Dinoprostone inhibits the reaction [NR2F2 protein binds to CYP19A1 promoter]	19001523
D015232	Dinoprostone	Dinoprostone inhibits the reaction [WT1 protein binds to CYP19A1 promoter]	19001523
D015232	Dinoprostone	Dinoprostone promotes the reaction [ESRRA protein binds to CYP19A1 promoter]	20351196
D015232	Dinoprostone	Dinoprostone promotes the reaction [ESRRA protein results in increased expression of CYP19A1 mRNA]	20351196
D015232	Dinoprostone	Dinoprostone promotes the reaction [ESRRA protein results in increased expression of CYP19A1 protein]	20351196
D015232	Dinoprostone	Dinoprostone promotes the reaction [NR5A1 protein binds to CYP19A1 promoter]	19001523
D015232	Dinoprostone	Dinoprostone results in increased activity of CYP19A1 protein	15862962\|1602424
D015232	Dinoprostone	Dinoprostone results in increased expression of CYP19A1 mRNA	16024248\|1900152
D015232	Dinoprostone	Dinoprostone results in increased expression of CYP19A1 protein	20351196\|2067855
D015232	Dinoprostone	ESRRA protein promotes the reaction [Dinoprostone results in increased expression of CYP19A1 mRNA]	20351196
D015232	Dinoprostone	ESRRA protein promotes the reaction [Dinoprostone results in increased expression of CYP19A1 protein]	20351196
D015232	Dinoprostone	Dinoprostone results in increased activity of CYP19A1 protein	23054057
D015232	Dinoprostone	Dinoprostone results in increased expression of CYP19A1	17315855
C031181	phenanthrene	[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of CYP19A1 protein	28803881
C031181	phenanthrene	phenanthrene results in increased expression of CYP19A1 protein	28803881
D010634	Phenobarbital	Phenobarbital promotes the reaction [Valproic Acid results in decreased activity of CYP19A1 protein]	17959350
D010634	Phenobarbital	Phenobarbital results in decreased activity of CYP19A1 protein	17959350
D019800	Phenol	Phenol inhibits the reaction [LHB protein results in increased expression of CYP19A1 mRNA]	23423282
D010672	Phenytoin	Phenytoin results in decreased activity of CYP19A1 protein	17959350
C085059	phloxine	phloxine results in decreased activity of CYP19A1 protein	18310892
D064209	Phytochemicals	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
C011994	pirimicarb	pirimicarb results in increased activity of CYP19A1 protein	11884232
C006253	pirinixic acid	pirinixic acid results in decreased expression of CYP19A1 mRNA	19162173
D010894	Piroxicam	Piroxicam inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D010894	Piroxicam	Piroxicam results in decreased activity of CYP19A1 protein	15964185
D010894	Piroxicam	Piroxicam results in decreased expression of CYP19A1 mRNA	15964185
D010968	Plasticizers	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
D011078	Polychlorinated Biphenyls	Polychlorinated Biphenyls results in decreased expression of CYP19A1 mRNA	20924025
D011192	Potassium Dichromate	Potassium Dichromate results in increased expression of CYP19A1 mRNA	23608068
C045362	prochloraz	[prochloraz co-treated with Chlorpyrifos co-treated with triflusulfuron-methyl] results in increased expression of CYP19A1 mRNA	25233012
C045362	prochloraz	[prochloraz co-treated with epoxiconazole co-treated with cyproconazole] results in increased expression of CYP19A1 mRNA	25233012
C045362	prochloraz	prochloraz results in decreased activity of CYP19A1 protein	10806373\|1188423
C045362	prochloraz	prochloraz results in increased activity of CYP19A1 protein	20087668
C045362	prochloraz	prochloraz results in increased expression of CYP19A1 mRNA	25233012\|2576547
C045362	prochloraz	prochloraz results in decreased activity of CYP19A1 protein	17081805
C045362	prochloraz	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
C045362	prochloraz	prochloraz results in decreased activity of CYP19A1 protein	15788727\|2008766
C035988	procymidone	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
C024273	profenofos	profenofos results in decreased expression of CYP19A1 mRNA	18828448
D011374	Progesterone	Progesterone results in decreased expression of CYP19A1 mRNA	22130322
D011374	Progesterone	Progesterone results in increased activity of CYP19A1 protein	15862960
D011374	Progesterone	[FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone	22067323
D011374	Progesterone	IGF1 protein promotes the reaction [[FSHB protein results in increased expression of CYP19A1 mRNA] which results in increased abundance of Progesterone]	22067323
C033205	propamocarb	propamocarb results in increased activity of CYP19A1 protein	11884232
C100043	propazine	formestane inhibits the reaction [propazine results in increased activity of CYP19A1 protein]	10746939
C100043	propazine	propazine results in increased activity of CYP19A1 protein	10746939\|1167526
C100043	propazine	propazine results in increased expression of CYP19A1 mRNA	10746939\|1167526
C045950	propiconazole	propiconazole results in decreased activity of CYP19A1 protein	16996190
C045950	propiconazole	propiconazole results in decreased activity of CYP19A1 protein	17081805
C045950	propiconazole	propiconazole results in increased expression of CYP19A1 mRNA	23339182
C045950	propiconazole	[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA	23954766
C006068	propylparaben	propylparaben affects the expression of CYP19A1 mRNA	23744433
C006068	propylparaben	propylparaben affects the expression of CYP19A1 protein	23744433
D015237	Dinoprost	Dinoprost results in increased expression of CYP19A1 mRNA	18818292
D015237	Dinoprost	GNRH1 protein inhibits the reaction [Dinoprost results in increased expression of CYP19A1 mRNA]	18818292
D015237	Dinoprost	Dinoprost results in decreased expression of CYP19A1 mRNA	15271885
D015237	Dinoprost	Dinoprost promotes the reaction [GATA4 protein binds to CYP19A1 promoter]	15271885
D015237	Dinoprost	Dinoprost results in decreased expression of CYP19A1 mRNA	11517196\|1527188
D015237	Dinoprost	Dinoprost results in decreased expression of CYP19A1 protein	15271885
D015237	Dinoprost	[epostane co-treated with Dinoprost] results in increased expression of CYP19A1 mRNA	20739670
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [LEP protein results in increased expression of CYP19A1 mRNA]	28571770
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [LEP protein results in increased expression of CYP19A1 protein]	28571770
C432165	pyrazolanthrone	"pyrazolanthrone inhibits the reaction [o,p'-DDT results in increased expression of CYP19A1 protein]"	20678559
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [bisphenol A results in increased expression of CYP19A1 mRNA]	28697429
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [bisphenol A results in increased expression of CYP19A1 protein]	28697429
C432165	pyrazolanthrone	pyrazolanthrone inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C030984	pyrene	[naphthalene co-treated with anthracene co-treated with phenanthrene co-treated with pyrene] affects the expression of CYP19A1 protein	28803881
C030984	pyrene	pyrene affects the expression of CYP19A1 protein	28803881
D011794	Quercetin	Quercetin results in decreased activity of CYP19A1 protein	16023337\|1696591
D011794	Quercetin	Quercetin results in decreased expression of CYP19A1 mRNA	10704911\|1696591
D011794	Quercetin	Quercetin results in increased activity of CYP19A1 protein	15319488
D011794	Quercetin	Quercetin results in increased expression of CYP19A1 mRNA	15319488
C502851	quinocetone	quinocetone results in decreased expression of CYP19A1 mRNA	27046791
D020849	Raloxifene Hydrochloride	[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA	19059307
D020849	Raloxifene Hydrochloride	Raloxifene Hydrochloride results in decreased expression of CYP19A1 mRNA	10704911
C059514	resveratrol	resveratrol analog results in decreased activity of CYP19A1 protein	27159630
C059514	resveratrol	resveratrol analog results in increased expression of CYP19A1 mRNA	24610083
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol promotes the reaction [ESR1 results in increased expression of CYP19A1 mRNA alternative form]]	18462857
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol promotes the reaction [ESR1 results in increased expression of CYP19A1 protein]]	18462857
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol results in increased expression of CYP19A1 mRNA alternative form]	18462857
C059514	resveratrol	resveratrol inhibits the reaction [Estradiol results in increased expression of CYP19A1 protein]	18462857
C059514	resveratrol	resveratrol inhibits the reaction [MAPK3 results in increased expression of CYP19A1 protein]	18462857
C059514	resveratrol	resveratrol metabolite results in decreased activity of CYP19A1 protein	20527891
C059514	resveratrol	resveratrol results in decreased activity of CYP19A1 protein	16611627\|1776606
C059514	resveratrol	resveratrol results in decreased expression of CYP19A1 mRNA	16611627\|1776606
C059514	resveratrol	resveratrol results in increased expression of CYP19A1 mRNA	22357324
C059514	resveratrol	resveratrol results in increased expression of CYP19A1 protein	22357324
C049837	rogletimide	rogletimide results in decreased activity of CYP19A1 protein	1659868
D012395	Rose Bengal	Rose Bengal results in decreased activity of CYP19A1 protein	18310892
D012402	Rotenone	Rotenone results in decreased activity of CYP19A1 protein	15319488
C085746	rottlerin	rottlerin results in decreased activity of CYP19A1 protein	15955695
C541923	sandostatinLAR	sandostatinLAR results in decreased expression of CYP19A1 mRNA	17210224
C406525	SB 239063	SB 239063 inhibits the reaction [bisphenol A results in increased expression of and results in increased activity of CYP19A1 protein]	20096755
C115461	SC 560	SC 560 results in decreased activity of CYP19A1 protein	15964185
C115461	SC 560	SC 560 results in decreased expression of CYP19A1 mRNA	15964185
D017632	Asbestos, Serpentine	"Asbestos, Serpentine results in decreased expression of CYP19A1 mRNA"	24160326
D020280	Sertraline	Sertraline results in decreased activity of CYP19A1 protein	26162595
D012715	Sesame Oil	Sesame Oil results in increased expression of CYP19A1 mRNA	29191790
D012834	Silver	Silver analog results in decreased expression of CYP19A1 protein	27746313
D012834	Silver	Silver results in decreased expression of CYP19A1 mRNA	28646569
D012839	Simazine	formestane inhibits the reaction [Simazine results in increased activity of CYP19A1 protein]	10746939
D012839	Simazine	Simazine results in increased activity of CYP19A1 protein	10746939\|1167526
D012839	Simazine	Simazine results in increased expression of CYP19A1 mRNA	10746939\|1167526
D012906	Smoke	Smoke results in increased expression of CYP19A1 mRNA	23693141
C110881	S-nitro-N-acetylpenicillamine	S-nitro-N-acetylpenicillamine results in decreased activity of CYP19A1 protein	10338361
C110881	S-nitro-N-acetylpenicillamine	S-nitro-N-acetylpenicillamine results in decreased expression of CYP19A1 mRNA	10338361
C009277	sodium arsenate	sodium arsenate results in decreased expression of CYP19A1 mRNA	26393310
C017947	sodium arsenite	letrozole inhibits the reaction [sodium arsenite results in increased expression of CYP19A1 mRNA]	24068038
C017947	sodium arsenite	sodium arsenite results in increased expression of CYP19A1 mRNA	24068038
C017947	sodium arsenite	sodium arsenite results in increased expression of CYP19A1 protein	24068038
C017947	sodium arsenite	sodium arsenite results in increased expression of CYP19A1 mRNA	17077188
D012969	Sodium Fluoride	Sodium Fluoride results in decreased expression of CYP19A1 mRNA	27862939
D013473	Sunscreening Agents	"[perfluorononanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA"	25588985
D013605	T-2 Toxin	T-2 Toxin results in decreased expression of CYP19A1 mRNA	22982764
D013629	Tamoxifen	Tamoxifen analog results in increased expression of CYP19A1 mRNA	19549922
D013629	Tamoxifen	[Tamoxifen co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA	19059307
D013629	Tamoxifen	Tamoxifen inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]	21296134
D013629	Tamoxifen	[Tamoxifen inhibits the reaction [Aflatoxin B1 results in increased expression of CYP19A1 mRNA]] which results in decreased chemical synthesis of aflatoxicol	21296134
D013629	Tamoxifen	Tamoxifen inhibits the reaction [diethyl phthalate promotes the reaction [ESR1 protein binds to CYP19A1 promoter]]	24994688
D013629	Tamoxifen	Tamoxifen inhibits the reaction [ESR1 protein binds to CYP19A1 promoter]	24994688
D013629	Tamoxifen	Tamoxifen results in decreased expression of CYP19A1 mRNA	10704911\|2129613
C087114	tebuconazole	tebuconazole results in decreased activity of CYP19A1 protein	12127262
C037565	terbutylazine	[bitertanol co-treated with propiconazole co-treated with cypermethrin co-treated with Malathion co-treated with terbutylazine] results in increased expression of CYP19A1 mRNA	23954766
D013738	Testolactone	Testolactone results in decreased activity of CYP19A1 protein	16026110
D013739	Testosterone	fulvestrant inhibits the reaction [[Testosterone co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA]	16641147
D013739	Testosterone	fulvestrant inhibits the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	16641147
D013739	Testosterone	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Testosterone co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA]	16641147
D013739	Testosterone	[Testosterone co-treated with FSHB protein] results in increased expression of CYP19A1 mRNA	16641147
D013739	Testosterone	Testosterone results in increased expression of CYP19A1 mRNA	16641147
D013739	Testosterone	[Atrazine results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone	20087668
D013739	Testosterone	[Colforsin results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone	20087668
D013739	Testosterone	CYP19A1 gene SNP affects the abundance of Testosterone	16949385
D013739	Testosterone	CYP19A1 protein affects the metabolism of Testosterone	11751016\|1603016
D013739	Testosterone	[Finasteride co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	23523586
D013739	Testosterone	Finasteride promotes the reaction [[tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	23523586
D013739	Testosterone	[FSHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	18535249
D013739	Testosterone	Testosterone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
D013739	Testosterone	Testosterone results in increased expression of CYP19A1 mRNA	23523586
D013739	Testosterone	TNF protein promotes the reaction [CYP19A1 protein affects the metabolism of Testosterone]	16030167
D013739	Testosterone	[tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	23523586
D013739	Testosterone	tributyltin inhibits the reaction [CYP19A1 protein affects the metabolism of Testosterone]	11751016
D013739	Testosterone	tributyltin promotes the reaction [[Finasteride co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	23523586
D013739	Testosterone	[Calcimycin co-treated with Testosterone] results in decreased activity of CYP19A1 protein	16102761
D013739	Testosterone	[Ionomycin co-treated with Testosterone] results in decreased activity of CYP19A1 protein	16102761
D013739	Testosterone	Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	22285649
D013739	Testosterone	[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	22285649
D013739	Testosterone	[Leuprolide co-treated with Testosterone] results in decreased expression of CYP19A1 mRNA	16032706
D013739	Testosterone	Testosterone results in decreased expression of CYP19A1 mRNA	20600201
D013739	Testosterone	[titanium dioxide results in increased expression of CYP19A1 mRNA] which results in increased metabolism of Testosterone	24241477
D013739	Testosterone	AR mutant form inhibits the reaction [Testosterone results in increased expression of CYP19A1 protein]	21273442
D013739	Testosterone	bicalutamide inhibits the reaction [Testosterone results in increased expression of CYP19A1 protein]	21273442
D013739	Testosterone	[carbamylhydrazine results in increased activity of CYP19A1 protein] which results in increased abundance of Testosterone metabolite	19788891
D013739	Testosterone	CYP19A1 protein affects the metabolism of Testosterone	16080194
D013739	Testosterone	CYP19A1 protein results in increased metabolism of Testosterone	16569475
D013739	Testosterone	Finasteride promotes the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	21273442
D013739	Testosterone	formestane promotes the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	21273442
D013739	Testosterone	NR5A2 mutant form inhibits the reaction [Testosterone results in increased expression of CYP19A1 mRNA]	21273442
D013739	Testosterone	Testosterone promotes the reaction [FSHB results in increased expression of CYP19A1 mRNA]	21273442
D013739	Testosterone	Testosterone promotes the reaction [NR5A2 protein binds to CYP19A1 promoter]	21273442
D013739	Testosterone	Testosterone results in increased expression of CYP19A1 mRNA	15525594\|2127344
D013739	Testosterone	[Testosterone results in increased expression of CYP19A1 mRNA] which results in increased abundance of Estradiol	21273442
D013739	Testosterone	Testosterone results in increased expression of CYP19A1 protein	15525594\|2127344
D013739	Testosterone	[Testosterone results in increased expression of CYP19A1 protein] which results in increased abundance of Estradiol	21273442
D013739	Testosterone	"[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Testosterone] affects the activity of CYP19A1 protein"	16151981
D013739	Testosterone	"[3,4,5,3',4'-pentachlorobiphenyl co-treated with Testosterone] results in increased activity of CYP19A1 protein"	16151981
D013739	Testosterone	CYP19A1 protein results in increased hydroxylation of Testosterone	9435150
D013739	Testosterone	CYP19A1 protein results in increased metabolism of Testosterone	21273442
D013739	Testosterone	FSHB protein promotes the reaction [[PRKACA protein mutant form co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	18535249
D013739	Testosterone	[PRKACA protein mutant form co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	18535249
C004648	testosterone enanthate	testosterone enanthate results in decreased expression of CYP19A1 mRNA	21427060
C004648	testosterone enanthate	testosterone enanthate results in increased expression of CYP19A1 mRNA	21427060
C020806	tetrabromobisphenol A	tetrabromobisphenol A analog results in decreased activity of CYP19A1 protein	16177243
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in increased expression of CYP19A1 protein	25223798
C102881	tetrabutyltin	tetrabutyltin results in increased expression of CYP19A1 mRNA	15941851
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP19A1 mRNA	24398026
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the reaction [LHB protein results in increased expression of CYP19A1 mRNA]	24398026
D013749	Tetrachlorodibenzodioxin	3'-methoxy-4'-nitroflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D013749	Tetrachlorodibenzodioxin	alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 protein]	20823264
D013749	Tetrachlorodibenzodioxin	EGTA acetoxymethyl ester inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D013749	Tetrachlorodibenzodioxin	methyl arachidonylfluorophosphonate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D013749	Tetrachlorodibenzodioxin	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D013749	Tetrachlorodibenzodioxin	Piroxicam inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA]	19147701
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the activity of CYP19A1 protein	12916318
D013749	Tetrachlorodibenzodioxin	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
D013749	Tetrachlorodibenzodioxin	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid] results in increased expression of CYP19A1 mRNA"	25765474
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 mRNA	25697571
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 protein	20823264
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased activity of CYP19A1 protein	19962423
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA	11489354\|1505679
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP19A1 protein	19962423
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased stability of CYP19A1 mRNA	19962423
D013749	Tetrachlorodibenzodioxin	U 0126 inhibits the reaction [Tetrachlorodibenzodioxin results in increased stability of CYP19A1 mRNA]	19962423
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 mRNA	22889882\|2479343
D013749	Tetrachlorodibenzodioxin	"Gonadotropins, Equine inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 mRNA]"	19276399
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP19A1 mRNA	18284931
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of CYP19A1 protein	18284931
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]	11026553
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased activity of CYP19A1 protein	16141434
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of CYP19A1 mRNA	11026553\|1150023
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of CYP19A1 mRNA	15590112
D013755	Tetradecanoylphorbol Acetate	alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]	16357189
D013755	Tetradecanoylphorbol Acetate	[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA	16357189
D013755	Tetradecanoylphorbol Acetate	NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]	16357189
D013755	Tetradecanoylphorbol Acetate	Tetradecanoylphorbol Acetate results in decreased activity of CYP19A1 protein	10338361
D013764	Tetrahydronaphthalenes	Tetrahydronaphthalenes results in decreased activity of CYP19A1 protein	15743198
C417209	thiacloprid	thiacloprid results in increased activity of CYP19A1 protein	26464060\|2875089
C417209	thiacloprid	thiacloprid results in increased expression of CYP19A1 mRNA	26464060
C416660	thiamethoxam	thiamethoxam results in increased activity of CYP19A1 protein	26464060\|2875089
C416660	thiamethoxam	thiamethoxam results in increased expression of CYP19A1 mRNA	26464060
C484911	thioxanthone	thioxanthone analog results in increased expression of CYP19A1 mRNA	23208609
C059205	tiagabine	tiagabine results in decreased activity of CYP19A1 protein	17959350
C078041	tin sulfide	tin sulfide results in increased expression of CYP19A1 mRNA	29069489
C009495	titanium dioxide	titanium dioxide results in increased expression of CYP19A1 mRNA	24241477
C009495	titanium dioxide	[titanium dioxide results in increased expression of CYP19A1 mRNA] which results in increased metabolism of Testosterone	24241477
C009495	titanium dioxide	titanium dioxide results in increased expression of CYP19A1 protein	24241477
C009495	titanium dioxide	titanium dioxide results in decreased expression of CYP19A1 mRNA	26277626
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased activity of CYP19A1 protein	27189315
D014112	Toxaphene	Toxaphene results in decreased activity of CYP19A1 protein	16996190
D014118	Toxins, Biological	"Toxins, Biological affects the expression of CYP19A1 mRNA"	19682533
C494251	trans-phytol	trans-phytol results in decreased expression of CYP19A1 mRNA	24853760
C494251	trans-phytol	trans-phytol results in decreased expression of CYP19A1 protein	24853760
D014204	Trenbolone Acetate	Trenbolone Acetate results in increased expression of CYP19A1 mRNA	28108667
C064709	trestolone	trestolone inhibits the reaction [CYP19A1 protein affects the metabolism of Androstenedione]	12628686
D014212	Tretinoin	[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CYP19A1 mRNA	16443354
D014212	Tretinoin	Tretinoin results in increased expression of CYP19A1 mRNA	15941851
C072782	tri-(2-chloroisopropyl)phosphate	tri-(2-chloroisopropyl)phosphate results in increased expression of CYP19A1 mRNA	22446829
C032910	triadimefon	triadimefon results in decreased activity of CYP19A1 protein	10806373
C032910	triadimefon	triadimefon results in decreased activity of CYP19A1 protein	17081805
C533760	tribromodiphenyl ether 28	tribromodiphenyl ether 28 metabolite results in decreased activity of CYP19A1 protein	18022659
C533760	tribromodiphenyl ether 28	tribromodiphenyl ether 28 metabolite results in increased expression of CYP19A1 mRNA	18248924
C011559	tributyltin	Finasteride promotes the reaction [[tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	23523586
C011559	tributyltin	"[Tetrachlorodibenzodioxin co-treated with 3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with perfluorooctane sulfonic acid co-treated with hexabromocyclododecane co-treated with 2,2',4,4'-tetrabromodiphenyl ether co-treated with tributyltin co-treated with methylmercuric chloride] results in increased expression of CYP19A1 mRNA"	25765474
C011559	tributyltin	[tributyltin binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein	15941851
C011559	tributyltin	[tributyltin co-treated with Testosterone] results in increased expression of CYP19A1 mRNA	23523586
C011559	tributyltin	tributyltin inhibits the reaction [CYP19A1 protein affects the metabolism of Testosterone]	11751016
C011559	tributyltin	tributyltin inhibits the reaction [CYP19A1 protein binds to and results in increased metabolism of Androstenedione]	11522339
C011559	tributyltin	tributyltin promotes the reaction [[Finasteride co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]	23523586
C011559	tributyltin	tributyltin results in decreased activity of CYP19A1 protein	11522339\|1175101
C011559	tributyltin	tributyltin results in increased activity of CYP19A1 protein	16996190
C011559	tributyltin	tributyltin results in increased expression of CYP19A1 mRNA	15941851\|1699619
C011559	tributyltin	tributyltin results in increased expression of CYP19A1 protein	23523586
C011559	tributyltin	tributyltin results in decreased activity of CYP19A1 protein	18310892
C011559	tributyltin	[Ethinyl Estradiol co-treated with tributyltin] affects the activity of CYP19A1 protein	16484284
C011559	tributyltin	tributyltin results in decreased activity of CYP19A1 protein	16484284
C011559	tributyltin	tributyltin results in decreased activity of CYP19A1 protein	15276081
D014260	Triclosan	Triclosan results in increased expression of CYP19A1 mRNA	29032082
C413391	triflusulfuron-methyl	[prochloraz co-treated with Chlorpyrifos co-treated with triflusulfuron-methyl] results in increased expression of CYP19A1 mRNA	25233012
C030665	triphenyltin	triphenyltin affects the activity of CYP19A1 protein	20708649
C012594	triphenyltin chloride	triphenyltin chloride results in increased expression of CYP19A1 mRNA	15941851
C007567	triphenyltin hydroxide	[triphenyltin hydroxide binds to and results in increased activity of RXRA protein] which results in increased expression of CYP19A1 protein	15941851
C007567	triphenyltin hydroxide	triphenyltin hydroxide results in increased expression of CYP19A1 mRNA	15941851
C016805	tris(1,3-dichloro-2-propyl)phosphate	"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of CYP19A1 mRNA"	22446829\|2617987
C013320	tris(2-butoxyethyl) phosphate	tris(2-butoxyethyl) phosphate results in increased expression of CYP19A1 mRNA	29024780
C031324	tris(chloroethyl)phosphate	tris(chloroethyl)phosphate results in increased expression of CYP19A1 mRNA	22446829
C057693	troglitazone	LG 100268 promotes the reaction [troglitazone results in decreased activity of CYP19A1 mRNA]	10814527
C057693	troglitazone	LG 100268 promotes the reaction [troglitazone results in decreased activity of CYP19A1 protein]	10814527
C057693	troglitazone	troglitazone promotes the reaction [LG 100268 results in decreased activity of CYP19A1 mRNA]	10814527
C057693	troglitazone	troglitazone promotes the reaction [LG 100268 results in decreased activity of CYP19A1 protein]	10814527
C057693	troglitazone	troglitazone results in decreased activity of CYP19A1 protein	10814527
C057693	troglitazone	troglitazone results in decreased expression of CYP19A1 mRNA	10814527
C057693	troglitazone	troglitazone results in decreased expression of CYP19A1 mRNA	12706301
C057693	troglitazone	[troglitazone results in decreased activity of CYP19A1 protein] inhibits the reaction [[CYP19A1 protein results in increased metabolism of Androgens] which results in increased chemical synthesis of Estrogens]	10814527
C080163	trovafloxacin	trovafloxacin results in decreased activity of CYP19A1 protein	26141389
C113580	U 0126	U 0126 inhibits the reaction [Estradiol results in increased expression of CYP19A1 mRNA alternative form]	18462857
C113580	U 0126	U 0126 inhibits the reaction [LHB protein results in decreased expression of CYP19A1 mRNA]	23071612
C113580	U 0126	U 0126 inhibits the reaction [MAPK3 results in increased expression of CYP19A1 protein]	18462857
C113580	U 0126	U 0126 inhibits the reaction [Tetrachlorodibenzodioxin results in increased stability of CYP19A1 mRNA]	19962423
C113580	U 0126	U 0126 inhibits the reaction [Atrazine inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]]	23583632
D014520	Urethane	Urethane results in decreased expression of CYP19A1 mRNA	28818685
D014635	Valproic Acid	Valproic Acid inhibits the reaction [FSHB protein results in increased expression of CYP19A1 mRNA]	23152920
D014635	Valproic Acid	Phenobarbital promotes the reaction [Valproic Acid results in decreased activity of CYP19A1 protein]	17959350
D014635	Valproic Acid	Valproic Acid affects the expression of CYP19A1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid inhibits the reaction [Colforsin results in increased activity of CYP19A1 protein]	20726872
D014635	Valproic Acid	Valproic Acid inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]	20726872
D014635	Valproic Acid	Valproic Acid results in decreased activity of CYP19A1 protein	17959350
D014635	Valproic Acid	Valproic Acid results in decreased expression of CYP19A1 mRNA	25716160
D014635	Valproic Acid	Valproic Acid results in increased expression of CYP19A1 mRNA	27188386
D001335	Vehicle Emissions	Vehicle Emissions results in increased methylation of CYP19A1 gene	25560391
C025643	vinclozolin	[vinclozolin co-treated with Atrazine] results in decreased activity of CYP19A1 protein	17599374
C025643	vinclozolin	"[vinclozolin co-treated with o,p'-DDT] results in decreased activity of CYP19A1 protein"	17599374
C025643	vinclozolin	vinclozolin results in increased activity of CYP19A1 protein	12127262
C025643	vinclozolin	vinclozolin results in increased expression of CYP19A1 mRNA	12127262
C025643	vinclozolin	[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP19A1 mRNA	25607892
C025643	vinclozolin	[vinclozolin co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of CYP19A1 mRNA	22120136
C025643	vinclozolin	[vinclozolin co-treated with LHB protein] results in increased expression of CYP19A1 mRNA	22120136
C025643	vinclozolin	vinclozolin metabolite results in increased expression of CYP19A1 mRNA	23326527
C025643	vinclozolin	vinclozolin promotes the reaction [FSHB protein results in increased activity of CYP19A1 protein]	22120136
C025643	vinclozolin	vinclozolin results in increased expression of CYP19A1 mRNA	22285353
C025643	vinclozolin	vinclozolin results in increased expression of CYP19A1 protein	22285353
C099734	vinyltributylstannane	vinyltributylstannane results in increased expression of CYP19A1 mRNA	15941851
D014810	Vitamin E	Vitamin E results in decreased expression of CYP19A1 mRNA	15084515
C060523	vorozole	vorozole results in decreased activity of CYP19A1 protein	15518995
C060523	vorozole	vorozole results in decreased activity of CYP19A1 protein	16714371
C060523	vorozole	vorozole analog binds to CYP19A1 protein	9720668
C060523	vorozole	vorozole analog binds to CYP19A1 protein	9720668
D014874	Water Pollutants, Chemical	"N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Water Pollutants, Chemical analog results in increased expression of CYP19A1 mRNA]"	21932247
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical analog results in increased activity of CYP19A1 protein"	20466405
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical analog results in increased expression of CYP19A1 mRNA"	20466405\|2193224
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased activity of CYP19A1 protein"	20466405
D014874	Water Pollutants, Chemical	"[Water Pollutants, Chemical results in increased activity of CYP19A1 protein] which results in decreased metabolism of Estradiol"	20466405
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical results in increased expression of CYP19A1 mRNA"	20466405
C096486	YM 511	YM 511 results in decreased activity of CYP19A1 protein	12926103\|8809200
C519312	Zyflamend	Zyflamend inhibits the reaction [Dietary Fats results in increased activity of CYP19A1 protein]	23880231
C519312	Zyflamend	Zyflamend inhibits the reaction [Dietary Fats results in increased expression of CYP19A1 mRNA]	23880231

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005506	iron ion binding	-	IEA	-
GO:0008395	steroid hydroxylase activity	-	TAS	-
GO:0009055	electron transfer activity	-	TAS	2848247
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	-	TAS	1371509
GO:0019825	oxygen binding	-	TAS	2848247
GO:0020037	heme binding	-	IDA	19129847
GO:0070330	aromatase activity	-	IDA	19129847 26482249

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0002677	negative regulation of chronic inflammatory response	-	IEA	-
GO:0006694	steroid biosynthetic process	-	TAS	2848247
GO:0006703	estrogen biosynthetic process	-	TAS	-
GO:0006710	androgen catabolic process	-	IDA	26482249
GO:0008585	female gonad development	-	IEA	-
GO:0010760	negative regulation of macrophage chemotaxis	-	IEA	-
GO:0016125	sterol metabolic process	-	TAS	-
GO:0022900	electron transport chain	-	IEA	-
GO:0030540	female genitalia development	-	IEA	-
GO:0030879	mammary gland development	-	IEA	-
GO:0060065	uterus development	-	IEA	-
GO:0060736	prostate gland growth	-	IEA	-
GO:0061370	testosterone biosynthetic process	-	IEA	-
GO:2000866	positive regulation of estradiol secretion	-	IDA	26482249

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005783	endoplasmic reticulum	-	IDA	-
GO:0005789	endoplasmic reticulum membrane	-	TAS	-
GO:0016020	membrane	-	TAS	2848247

KEGG ID	KEGG Term
hsa00140	Steroid hormone biosynthesis
hsa01100	Metabolic pathways

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-1643685	Disease	TAS
R-HSA-193144	Estrogen biosynthesis	TAS
R-HSA-196071	Metabolism of steroid hormones	TAS
R-HSA-211859	Biological oxidations	TAS
R-HSA-211897	Cytochrome P450 - arranged by substrate type	TAS
R-HSA-211945	Phase I - Functionalization of compounds	TAS
R-HSA-211976	Endogenous sterols	TAS
R-HSA-556833	Metabolism of lipids	TAS
R-HSA-5579029	Metabolic disorders of biological oxidation enzymes	TAS
R-HSA-5579030	Defective CYP19A1 causes Aromatase excess syndrome (AEXS)	TAS
R-HSA-5668914	Diseases of metabolism	TAS
R-HSA-8957322	Metabolism of steroids	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
23197595	Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy. (2013 Mar)	O'Shaughnessy PJ	Mol Hum Reprod
24737458	Genetically predicted 17beta-estradiol and systemic inflammation in women: a separate-sample Mendelian randomisation analysis in the Guangzhou Biobank Cohort Study. (2014 Aug)	Zhao J	J Epidemiol Community Health
28746172	A genetic variant in the catechol-O-methyl transferase (COMT) gene is related to age-dependent differences in the therapeutic effect of calcium-channel blockers. (2017 Jul)	Xu J	Medicine (Baltimore)
22104650	A genetic polymorphism in the CYP19A1 gene and the risk of hypertension among midlife women. (2012 Jan)	Ziv-Gal A	Maturitas
23669293	CYP19A1 gene polymorphisms and risk of lung cancer. (2013 Jun)	Zhang J	J Int Med Res
17928820	Microarray analysis of the global alterations in the gene expression in the placentas from cigarette-smoking mothers. (2008 Apr)	Huuskonen P	Clin Pharmacol Ther
21300759	EGFR L858R mutation and polymorphisms of genes related to estrogen biosynthesis and metabolism in never-smoking female lung adenocarcinoma patients. (2011 Apr 15)	Yang SY	Clin Cancer Res
27189315	The human placental proteome is affected by maternal smoking. (2016 Aug)	Huuskonen P	Reprod Toxicol
21790896	Genetic and environmental predictors, endogenous hormones and growth factors, and risk of estrogen receptor-positive breast cancer in Japanese women. (2011 Nov)	Yoshimoto N	Cancer Sci
26203295	Altered placental DNA methylation patterns associated with maternal smoking: current perspectives. (2015 May 7)	Maccani JZ	Adv Genomics Genet
22106445	HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genes. (2012 Jan 1)	Edwards TL	Am J Epidemiol
19630952	Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. (2009)	Crandall CJ	Breast Cancer Res
19174490	Tobacco and estrogen metabolic polymorphisms and risk of non-small cell lung cancer in women. (2009 Apr)	Cote ML	Carcinogenesis
21414724	The TTTAn aromatase (CYP19A1) polymorphism is associated with compulsive craving of male patients during alcohol withdrawal. (2011 Sep)	Lenz B	Psychoneuroendocrinology