| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| ZBED2 | 0.567 |
| KCNJ1 | 0.543 |
| ENTHD1 | 0.524 |
| AMBN | 0.523 |
| CHAT | 0.516 |
| DRD3 | 0.507 |
| LINC00534 | 0.505 |
| GPR101 | 0.502 |
| TMPRSS6 | 0.492 |
| SAG | 0.49 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| HPSE2 | -0.266 |
| RNF182 | -0.226 |
| CLDN1 | -0.22 |
| ALDH1A1 | -0.213 |
| SYTL2 | -0.208 |
| ART5 | -0.205 |
| PYGM | -0.201 |
| SH2D7 | -0.195 |
| C1orf189 | -0.188 |
| GTDC1 | -0.188 |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of NKX2-3 mRNA" | 27291303 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of NKX2-3 gene | 27153756 |
| C015001 | arsenite | arsenite results in increased methylation of NKX2-3 promoter | 23974009 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of NKX2-3 mRNA | 22228805 |
| C006780 | bisphenol A | bisphenol A affects the methylation of NKX2-3 promoter | 27334623 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of NKX2-3 mRNA | 25181051 |
| C118739 | entinostat | entinostat results in decreased expression of NKX2-3 mRNA | 27188386 |
| D053260 | Soot | Soot results in increased expression of NKX2-3 mRNA | 26551751 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of NKX2-3 mRNA | 24058054 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of NKX2-3 mRNA | 22298810 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of NKX2-3 mRNA" | 26179874 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of NKX2-3 mRNA | 25979313 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | - | ISA | - |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | - | ISM | 19274049 |
| GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | - | NAS | 19274049 |
| GO:0003674 | molecular_function | - | ND | - |
| GO:0043565 | sequence-specific DNA binding | - | IEA | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0001776 | leukocyte homeostasis | - | IEA | - |
| GO:0002317 | plasma cell differentiation | - | IEA | - |
| GO:0006351 | transcription, DNA-templated | - | IEA | - |
| GO:0006641 | triglyceride metabolic process | - | IEA | - |
| GO:0008150 | biological_process | - | ND | - |
| GO:0022612 | gland morphogenesis | - | IEA | - |
| GO:0030225 | macrophage differentiation | - | IEA | - |
| GO:0042127 | regulation of cell proliferation | - | IEA | - |
| GO:0042475 | odontogenesis of dentin-containing tooth | - | IEA | - |
| GO:0043367 | CD4-positive, alpha-beta T cell differentiation | - | IEA | - |
| GO:0045944 | positive regulation of transcription by RNA polymerase II | - | IEA | - |
| GO:0048535 | lymph node development | - | IEA | - |
| GO:0048536 | spleen development | - | IEA | - |
| GO:0048541 | Peyer's patch development | - | IEA | - |
| GO:0048621 | post-embryonic digestive tract morphogenesis | - | IEA | - |
| GO:0050900 | leukocyte migration | - | IEA | - |
| KEGG ID | KEGG Term |
|---|
| Reactome ID | Reactome Term | Evidence |
|---|
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 19953089 | Differences in genetic background between active smokers, passive smokers, and non-smokers with Crohn's disease. (2010 May) | van der Heide F | Am J Gastroenterol |