| C025205 | 1,10-phenanthroline | "1,10-phenanthroline results in decreased activity of AKR1C2 protein" | 12604236 |
| C012277 | 1,2-diamino-4-nitrobenzene | "1,2-diamino-4-nitrobenzene results in increased expression of AKR1C2 mRNA" | 26198647 |
| C100349 | 1-phenyl-1,2-propanedione | "1-phenyl-1,2-propanedione results in increased expression of AKR1C2 mRNA" | 20491607 |
| C514239 | 20-alpha-dihydrodydrogesterone | 20-alpha-dihydrodydrogesterone results in decreased activity of AKR1C2 protein | 22245609 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of AKR1C2 mRNA" | 25305463 |
| C027667 | 2-aminophenol | 2-aminophenol results in increased expression of AKR1C2 mRNA | 20491607 |
| C091423 | 2-chloromethylpyridine | 2-chloromethylpyridine results in increased expression of AKR1C2 mRNA | 26198647 |
| C051750 | 2-hexenal | 2-hexenal results in increased expression of AKR1C2 mRNA | 20491607 |
| C035957 | 2-hydroxyethyl acrylate | 2-hydroxyethyl acrylate results in increased expression of AKR1C2 mRNA | 20491607 |
| C055802 | 2-nonynoic acid methyl ester | 2-nonynoic acid methyl ester results in increased expression of AKR1C2 mRNA | 20491607 |
| C018156 | 3',3'',5',5''-tetrabromophenolphthalein | "3',3'',5',5''-tetrabromophenolphthalein results in decreased activity of AKR1C2 protein" | 12604236 |
| C014464 | 3,4-dichloroaniline | "3,4-dichloroaniline results in increased expression of AKR1C2 mRNA" | 24172598 |
| C012928 | 3-dimethylaminopropylamine | 3-dimethylaminopropylamine results in increased expression of AKR1C2 mRNA | 20491607 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C459179 | 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C032642 | 4-aminophenylarsenoxide | 4-aminophenylarsenoxide binds to AKR1C2 protein | 26598702 |
| C032642 | 4-aminophenylarsenoxide | arsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C2 protein] | 26598702 |
| C058818 | 4-benzoylbenzoic acid | 4-benzoylbenzoic acid analog results in decreased activity of AKR1C2 protein | 19010312 |
| C038193 | 4-hydroxybenzoic acid | 4-hydroxybenzoic acid analog results in decreased activity of AKR1C2 protein | 27163852 |
| C117714 | 4-hydroxyequilenin-o-quinone | [AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone | 21910479 |
| C027563 | 4-nitrobenzyl bromide | 4-nitrobenzyl bromide results in increased activity of AKR1C2 promoter | 21195160 |
| C027563 | 4-nitrobenzyl bromide | 4-nitrobenzyl bromide results in increased expression of AKR1C2 mRNA | 25724174 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | AKR1C2 protein results in increased metabolism of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 11306090 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 28257955 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | drospirenone inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Estradiol inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Ethinyl Estradiol inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Progesterone inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | Testosterone inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C029728 | 4-phenylenediamine | 4-phenylenediamine results in increased activity of AKR1C2 promoter | 21195160 |
| C029728 | 4-phenylenediamine | 4-phenylenediamine results in increased expression of AKR1C2 mRNA | 20491607|2572417 |
| C011421 | 5-chloro-2-methyl-4-isothiazolin-3-one | 5-chloro-2-methyl-4-isothiazolin-3-one results in increased activity of AKR1C2 promoter | 21195160 |
| C454687 | 5-dihydrodeoxycorticosterone | AKR1C2 protein affects the reduction of 5-dihydrodeoxycorticosterone | 12604236 |
| C454687 | 5-dihydrodeoxycorticosterone | AKR1C2 protein results in increased metabolism of 5-dihydrodeoxycorticosterone | 11995921 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C005399 | 9,10-phenanthrenequinone | "AKR1C2 protein results in increased metabolism of 9,10-phenanthrenequinone" | 17950253 |
| C005399 | 9,10-phenanthrenequinone | "AKR1C2 protein results in increased reduction of 9,10-phenanthrenequinone" | 21851338|2326171 |
| C005399 | 9,10-phenanthrenequinone | "AKR1C2 protein results in increased reduction of and affects the activity of 9,10-phenanthrenequinone" | 21910479 |
| C023723 | acenaphthene-1-ol | [AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol | 25446855 |
| C023723 | acenaphthene-1-ol | AKR1C2 protein results in increased oxidation of acenaphthene-1-ol | 23261716 |
| C023723 | acenaphthene-1-ol | dichloro(4-cymene)ruthenium(II) analog inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C023723 | acenaphthene-1-ol | dichloro(4-cymene)ruthenium(II) inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C023723 | acenaphthene-1-ol | Ruthenium Compounds analog inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of AKR1C2 mRNA | 29067470 |
| D020106 | Acrylamide | Acrylamide results in decreased expression of AKR1C2 mRNA | 28959563 |
| C106812 | adefovir dipivoxil | adefovir dipivoxil results in decreased expression of AKR1C2 mRNA | 25596134 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased methylation of AKR1C2 gene | 27153756 |
| D043582 | 5-alpha-Dihydroprogesterone | AKR1C2 protein affects the reduction of 5-alpha-Dihydroprogesterone | 12604236 |
| D043582 | 5-alpha-Dihydroprogesterone | AKR1C2 protein results in increased reduction of 5-alpha-Dihydroprogesterone | 11995921 |
| D004092 | 20-alpha-Dihydroprogesterone | AKR1C2 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone | 11158055 |
| D013196 | Dihydrotestosterone | AKR1C2 protein results in increased metabolism of and results in decreased activity of Dihydrotestosterone | 17170221 |
| D013196 | Dihydrotestosterone | AKR1C2 protein results in increased metabolism of Dihydrotestosterone | 14672942|2224560 |
| D013196 | Dihydrotestosterone | AKR1C2 protein results in increased reduction of Dihydrotestosterone | 11158055 |
| D013196 | Dihydrotestosterone | Flufenamic Acid inhibits the reaction [AKR1C2 protein results in increased metabolism of Dihydrotestosterone] | 14672942 |
| D013196 | Dihydrotestosterone | AKR1C2 protein results in decreased activity of Dihydrotestosterone | 19320734 |
| D000667 | Ampicillin | Ampicillin results in decreased expression of AKR1C2 mRNA | 21632981 |
| D015113 | Androstane-3,17-diol | "AKR1C2 protein results in increased chemical synthesis of Androstane-3,17-diol" | 11158055|1717022 |
| D000966 | Antimony Potassium Tartrate | Antimony Potassium Tartrate results in increased expression of AKR1C2 protein | 28713220 |
| C006632 | arsenic trioxide | AKR1C2 protein results in decreased susceptibility to arsenic trioxide | 20707922 |
| C006632 | arsenic trioxide | arsenic trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C2 protein] | 26598702 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of AKR1C2 mRNA | 21461292|2670570 |
| D017638 | Asbestos, Crocidolite | "Asbestos, Crocidolite results in decreased expression of AKR1C2 mRNA" | 18687144 |
| D001205 | Ascorbic Acid | Ascorbic Acid results in increased expression of AKR1C2 mRNA | 26198647 |
| D001241 | Aspirin | Aspirin results in decreased activity of AKR1C2 protein | 19010312 |
| D001379 | Azathioprine | Azathioprine results in increased expression of AKR1C2 mRNA | 22623647|2619864 |
| C012764 | baccharin | baccharin analog results in decreased activity of AKR1C2 protein | 25555457 |
| D001553 | Benzbromarone | Benzbromarone results in decreased activity of AKR1C2 protein | 12604236 |
| C030233 | benzo(a)pyrene-1,6-quinone | "AKR1C2 protein results in increased reduction of and affects the activity of benzo(a)pyrene-1,6-quinone" | 21910479 |
| C018003 | benzo(a)pyrene-3,6-quinone | "AKR1C2 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3,6-quinone" | 21910479 |
| C017228 | benzo(a)pyrene 7,8-dihydrodiol | "[AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol" | 21910479 |
| C076588 | benzo(a)pyrene-7,8-dione | "[AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione" | 21910479 |
| C076588 | benzo(a)pyrene-7,8-dione | "AKR1C2 protein results in increased chemical synthesis of benzo(a)pyrene-7,8-dione" | 22394341 |
| D001564 | Benzo(a)pyrene | AKR1C2 protein affects the susceptibility to Benzo(a)pyrene | 19800895 |
| D001564 | Benzo(a)pyrene | AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with methylparaoxon] | 19800895 |
| D001564 | Benzo(a)pyrene | AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with Methyl Parathion] | 19800895 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene promotes the reaction [Methyl Parathion results in increased activity of AKR1C2 protein] | 19800895 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of AKR1C2 mRNA | 15735009|1654541 |
| D001564 | Benzo(a)pyrene | Methyl Parathion promotes the reaction [Benzo(a)pyrene results in increased expression of AKR1C2 mRNA] | 19800895 |
| D001564 | Benzo(a)pyrene | [Particulate Matter co-treated with Benzo(a)pyrene] results in increased expression of AKR1C2 mRNA | 17612574 |
| D001564 | Benzo(a)pyrene | [Vehicle Emissions co-treated with Benzo(a)pyrene] results in increased expression of AKR1C2 mRNA | 17612574 |
| D001564 | Benzo(a)pyrene | AKR1C2 protein results in increased metabolism of Benzo(a)pyrene | 22394341 |
| D015123 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide | "7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of AKR1C2 mRNA" | 19150397 |
| C526327 | benzyl cinnamate | benzyl cinnamate results in increased expression of AKR1C2 mRNA | 20491607 |
| D004958 | Estradiol | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AKR1C2 mRNA | 19619570 |
| D004958 | Estradiol | Estradiol results in increased expression of AKR1C2 mRNA | 19619570 |
| D004958 | Estradiol | Estradiol inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C005961 | bis(tri-n-butyltin)oxide | bis(tri-n-butyltin)oxide results in increased expression of AKR1C2 mRNA | 26198647 |
| D000069286 | Bortezomib | Bortezomib affects the expression of AKR1C2 mRNA | 21215737 |
| D019819 | Budesonide | AKR1C2 protein results in increased reduction of Budesonide | 21276783 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of AKR1C2 mRNA | 12414654|1533650 |
| D002104 | Cadmium | Cadmium results in increased expression of AKR1C2 mRNA | 21120746|2117241 |
| D019256 | Cadmium Chloride | Cadmium Chloride affects the expression of AKR1C2 mRNA | 23828170 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of AKR1C2 mRNA | 25596134 |
| C037123 | cadmium sulfate | [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA | 18654764 |
| C055494 | caffeic acid phenethyl ester | caffeic acid phenethyl ester results in decreased activity of AKR1C2 protein | 27163852 |
| C005563 | captax | captax results in increased activity of AKR1C2 promoter | 21195160 |
| C005563 | captax | captax results in increased expression of AKR1C2 mRNA | 20491607|2071313 |
| D002635 | Chenodeoxycholic Acid | Chenodeoxycholic Acid binds to AKR1C2 protein | 8486699 |
| D002635 | Chenodeoxycholic Acid | Chenodeoxycholic Acid results in decreased activity of AKR1C2 protein | 8573067 |
| D002699 | Chlorambucil | Chlorambucil results in decreased expression of AKR1C2 mRNA | 26198647 |
| C004656 | chloroacetaldehyde | chloroacetaldehyde results in increased expression of AKR1C2 mRNA | 25596134 |
| D020245 | p-Chloromercuribenzoic Acid | "[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| D020245 | p-Chloromercuribenzoic Acid | p-Chloromercuribenzoic Acid results in increased expression of AKR1C2 mRNA | 26272509 |
| C100187 | chloropicrin | chloropicrin affects the expression of AKR1C2 mRNA | 26352163 |
| C100187 | chloropicrin | chloropicrin results in increased expression of AKR1C2 mRNA | 28476498 |
| D002911 | Chrysenes | AKR1C2 protein results in increased reduction of and affects the activity of Chrysenes | 21910479 |
| C059262 | cidofovir | cidofovir affects the expression of AKR1C2 mRNA | 25596134 |
| C039671 | ciglitazone | [ciglitazone binds to PPARG protein alternative form] which results in increased expression of AKR1C2 mRNA | 16197558 |
| C039671 | ciglitazone | [ciglitazone binds to PPARG protein] which results in increased expression of AKR1C2 mRNA | 16197558 |
| C012843 | cinnamic aldehyde | cinnamic aldehyde results in increased activity of AKR1C2 promoter | 21195160 |
| C012843 | cinnamic aldehyde | cinnamic aldehyde results in increased expression of AKR1C2 mRNA | 25724174|2624460 |
| C012843 | cinnamic aldehyde | NFE2L2 mRNA promotes the reaction [cinnamic aldehyde results in increased expression of AKR1C2 mRNA] | 26244607 |
| C020722 | cinnamyl alcohol | cinnamyl alcohol results in increased activity of AKR1C2 promoter | 21195160 |
| C007076 | citral | citral results in increased activity of AKR1C2 promoter | 21195160 |
| C007076 | citral | citral results in increased expression of AKR1C2 mRNA | 20491607 |
| D004002 | Clodronic Acid | Clodronic Acid results in increased expression of AKR1C2 mRNA | 25596134 |
| C005522 | cloxazolam | cloxazolam results in decreased activity of AKR1C2 protein | 12604236 |
| C018021 | cobaltous chloride | [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA | 18654764 |
| D009243 | NAD | [AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol | 25446855 |
| D009243 | NAD | dichloro(4-cymene)ruthenium(II) analog inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D009243 | NAD | dichloro(4-cymene)ruthenium(II) inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D009243 | NAD | Ruthenium Compounds analog inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D009249 | NADP | "[AKR1C2 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7,8-dihydrodiol" | 21910479 |
| D009249 | NADP | [AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of 4-hydroxyequilenin-o-quinone | 21910479 |
| D009249 | NADP | "[AKR1C2 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7,8-dione" | 21910479 |
| D009249 | NADP | [AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone | 23261716 |
| D009249 | NADP | NADP inhibits the reaction [AKR1C2 protein results in increased oxidation of Hydroxysteroids] | 14672942 |
| D009249 | NADP | NADP promotes the reaction [AKR1C2 protein results in increased reduction of cyclopentanone] | 23261716 |
| D009249 | NADP | Ursodeoxycholic Acid inhibits the reaction [[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone] | 23261716 |
| C075384 | coniferaldehyde | coniferaldehyde results in increased expression of AKR1C2 mRNA | 26275128 |
| C075384 | coniferaldehyde | coniferaldehyde results in increased expression of AKR1C2 protein | 26275128 |
| D003300 | Copper | [NSC 689534 binds to Copper] which results in increased expression of AKR1C2 mRNA | 20971185 |
| C013453 | cresidine | cresidine results in increased expression of AKR1C2 mRNA | 26198647 |
| C010092 | cresolphthalein | cresolphthalein results in decreased activity of AKR1C2 protein | 12604236 |
| D003471 | Cuprizone | Cuprizone results in decreased expression of AKR1C2 mRNA | 26577399 |
| C016327 | cyclopentanol | AKR1C2 protein results in increased oxidation of cyclopentanol | 23261716 |
| C007201 | cyclopentanone | [AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone | 23261716 |
| C007201 | cyclopentanone | AKR1C2 protein results in increased reduction of cyclopentanone | 23261716 |
| C007201 | cyclopentanone | NADP promotes the reaction [AKR1C2 protein results in increased reduction of cyclopentanone] | 23261716 |
| C007201 | cyclopentanone | Ursodeoxycholic Acid inhibits the reaction [[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone] | 23261716 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of AKR1C2 mRNA | 22147139|2556210 |
| D003630 | Daunorubicin | Daunorubicin results in increased activity of AKR1C2 protein | 15588138 |
| D003975 | Diazepam | Diazepam results in decreased activity of AKR1C2 protein | 11995921|1260423 |
| C041517 | dibenzo(a,l)pyrene | "[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C2 mRNA" | 17612574 |
| C041517 | dibenzo(a,l)pyrene | "[Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C2 mRNA" | 17612574 |
| C530610 | dichloro(4-cymene)ruthenium(II) | dichloro(4-cymene)ruthenium(II) analog inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| C530610 | dichloro(4-cymene)ruthenium(II) | dichloro(4-cymene)ruthenium(II) inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D002945 | Cisplatin | AKR1C2 protein results in decreased susceptibility to Cisplatin | 20953859 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C2 mRNA | 27392435 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of AKR1C2 mRNA | 26198647 |
| D002945 | Cisplatin | Cisplatin results in increased expression of AKR1C2 mRNA | 25596134 |
| C023635 | dienogest | dienogest results in decreased expression of AKR1C2 mRNA | 23183084 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in increased expression of AKR1C2 mRNA | 28412506 |
| C014476 | diethyl maleate | diethyl maleate results in increased expression of AKR1C2 mRNA | 20491607 |
| C011612 | diethyl sulfate | diethyl sulfate results in increased expression of AKR1C2 mRNA | 20491607 |
| D004101 | Dihydroxydihydrobenzopyrenes | AKR1C2 protein results in increased reduction of and affects the activity of Dihydroxydihydrobenzopyrenes | 21910479 |
| D004137 | Dinitrochlorobenzene | Dinitrochlorobenzene results in increased activity of AKR1C2 promoter | 21195160 |
| D004137 | Dinitrochlorobenzene | Dinitrochlorobenzene results in increased expression of AKR1C2 mRNA | 20491607|2071313 |
| D004178 | Diquat | Diquat results in increased expression of AKR1C2 mRNA | 21172416 |
| D004237 | Diuron | Diuron metabolite results in increased expression of AKR1C2 mRNA | 24172598 |
| C035144 | drospirenone | drospirenone inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| D000068538 | Dutasteride | Dutasteride results in increased expression of AKR1C2 mRNA | 16806904 |
| D004394 | Dydrogesterone | Dydrogesterone results in decreased activity of AKR1C2 protein | 22245609 |
| D004394 | Dydrogesterone | Dydrogesterone results in decreased expression of AKR1C2 mRNA | 23183084 |
| C118739 | entinostat | entinostat results in decreased expression of AKR1C2 mRNA | 27188386 |
| D004949 | Estazolam | Estazolam results in decreased activity of AKR1C2 protein | 11995921 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C040833 | ethyl acrylate | ethyl acrylate results in increased expression of AKR1C2 mRNA | 26198647 |
| C004919 | ethylene dimethacrylate | ethylene dimethacrylate results in increased activity of AKR1C2 promoter | 21195160 |
| D005020 | Ethyl Methanesulfonate | Ethyl Methanesulfonate results in increased expression of AKR1C2 mRNA | 23649840 |
| D005054 | Eugenol | Eugenol results in increased expression of AKR1C2 mRNA | 26198647 |
| C084519 | farnesal | farnesal results in increased expression of AKR1C2 mRNA | 20491607 |
| C001209 | fenamic acid | fenamic acid analog results in decreased activity of AKR1C2 protein | 19010312 |
| D011345 | Fenofibrate | Fenofibrate results in increased expression of AKR1C2 mRNA | 25596134 |
| C006012 | fenofibric acid | AKR1C2 protein results in increased reduction of fenofibric acid | 27599626 |
| D005439 | Flufenamic Acid | Flufenamic Acid inhibits the reaction [AKR1C2 protein results in increased metabolism of Dihydrotestosterone] | 14672942 |
| D005439 | Flufenamic Acid | Flufenamic Acid results in decreased activity of AKR1C2 protein | 12604236|8573067 |
| C007734 | flunisolide | AKR1C2 protein results in increased reduction of flunisolide | 21276783 |
| D005445 | Flunitrazepam | Flunitrazepam results in decreased activity of AKR1C2 protein | 11995921 |
| D016650 | Fluorescein-5-isothiocyanate | Fluorescein-5-isothiocyanate results in increased expression of AKR1C2 mRNA | 20491607 |
| D005472 | Fluorouracil | AKR1C2 protein affects the susceptibility to Fluorouracil | 16217747 |
| D005480 | Flurbiprofen | Flurbiprofen results in decreased activity of AKR1C2 protein | 19010312 |
| D005557 | Formaldehyde | Formaldehyde results in increased expression of AKR1C2 mRNA | 20491607|2065599 |
| C106014 | gedunin | gedunin results in increased expression of AKR1C2 mRNA | 17010675 |
| D005913 | Glipizide | Glipizide results in decreased activity of AKR1C2 protein | 26362498 |
| C010969 | gliquidone | gliquidone results in decreased activity of AKR1C2 protein | 26362498 |
| D005905 | Glyburide | Glyburide results in decreased activity of AKR1C2 protein | 26362498 |
| C071834 | glycidamide | glycidamide results in increased expression of AKR1C2 mRNA | 17822822 |
| D006034 | Glycyrrhetinic Acid | Glycyrrhetinic Acid results in decreased activity of AKR1C2 protein | 12604236 |
| D006037 | Glyoxal | Glyoxal results in increased activity of AKR1C2 promoter | 21195160 |
| D006037 | Glyoxal | Glyoxal results in increased expression of AKR1C2 mRNA | 25724174 |
| D006589 | Hexestrol | Hexestrol results in decreased activity of AKR1C2 protein | 12604236|8573067 |
| D006830 | Hydralazine | [Hydralazine co-treated with Valproic Acid] results in increased expression of AKR1C2 mRNA | 17183730 |
| D006854 | Hydrocortisone | AKR1C2 protein results in increased reduction of Hydrocortisone | 21276783 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide affects the expression of AKR1C2 mRNA | 23410634 |
| D006861 | Hydrogen Peroxide | [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 mRNA | 19320734 |
| D006861 | Hydrogen Peroxide | [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 protein | 19320734 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased expression of AKR1C2 mRNA | 12414654 |
| D006914 | Hydroxysteroids | AKR1C2 protein results in increased abundance of Hydroxysteroids | 14672942 |
| D006914 | Hydroxysteroids | AKR1C2 protein results in increased oxidation of Hydroxysteroids | 14672942 |
| D006914 | Hydroxysteroids | NADP inhibits the reaction [AKR1C2 protein results in increased oxidation of Hydroxysteroids] | 14672942 |
| D007052 | Ibuprofen | Ibuprofen results in decreased activity of AKR1C2 protein | 19010312|8573067 |
| D007069 | Ifosfamide | Ifosfamide results in increased expression of AKR1C2 mRNA | 25596134 |
| C006048 | imidazolidinyl urea | imidazolidinyl urea results in increased activity of AKR1C2 promoter | 21195160 |
| D007213 | Indomethacin | Indomethacin results in decreased activity of AKR1C2 protein | 12604236|1901031 |
| C036643 | isoeugenol | isoeugenol results in increased activity of AKR1C2 promoter | 21195160 |
| C036643 | isoeugenol | isoeugenol results in increased expression of AKR1C2 mRNA | 20491607 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C2 mRNA | 27392435 |
| C544151 | jinfukang | jinfukang results in increased expression of AKR1C2 mRNA | 27392435 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of AKR1C2 mRNA | 26752646 |
| C410337 | K 7174 | K 7174 results in increased expression of AKR1C2 mRNA | 24086573 |
| D007854 | Lead | Lead affects the splicing of AKR1C2 mRNA | 28903495 |
| C008261 | lead acetate | lead acetate results in increased expression of AKR1C2 mRNA | 22839698 |
| C029891 | lead chloride | [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of AKR1C2 mRNA | 18654764 |
| C029891 | lead chloride | lead chloride results in increased expression of AKR1C2 mRNA | 18654764 |
| C018584 | linalool | linalool results in increased expression of AKR1C2 mRNA | 20491607 |
| D008095 | Lithocholic Acid | AKR1C2 protein binds to Lithocholic Acid | 8573067 |
| D008095 | Lithocholic Acid | Lithocholic Acid binds to AKR1C2 protein | 8486699 |
| D008095 | Lithocholic Acid | Lithocholic Acid results in decreased activity of AKR1C2 protein | 12604236|8573067 |
| D008294 | Malathion | Malathion results in increased expression of AKR1C2 mRNA | 16079077 |
| D008469 | Meclofenamic Acid | Meclofenamic Acid results in decreased activity of AKR1C2 protein | 19010312|2636249 |
| D008472 | Medazepam | Medazepam results in decreased activity of AKR1C2 protein | 11995921|1260423 |
| D017258 | Medroxyprogesterone Acetate | Medroxyprogesterone Acetate results in decreased activity of AKR1C2 protein | 12604236|2224560 |
| D008528 | Mefenamic Acid | Mefenamic Acid analog results in decreased activity of AKR1C2 protein | 19010312 |
| C042720 | mercuric bromide | mercuric bromide results in increased expression of AKR1C2 mRNA | 26272509 |
| C042720 | mercuric bromide | "[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of AKR1C2 mRNA | 28001369 |
| D008741 | Methyl Methanesulfonate | Methyl Methanesulfonate results in increased expression of AKR1C2 mRNA | 23649840 |
| C008480 | methylparaoxon | AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with methylparaoxon] | 19800895 |
| C008480 | methylparaoxon | methylparaoxon results in increased expression of AKR1C2 mRNA | 19800895 |
| D008743 | Methyl Parathion | AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with Methyl Parathion] | 19800895 |
| D008743 | Methyl Parathion | Benzo(a)pyrene promotes the reaction [Methyl Parathion results in increased activity of AKR1C2 protein] | 19800895 |
| D008743 | Methyl Parathion | Methyl Parathion promotes the reaction [Benzo(a)pyrene results in increased expression of AKR1C2 mRNA] | 19800895 |
| D008743 | Methyl Parathion | Methyl Parathion results in increased activity of AKR1C2 protein | 19800895 |
| D008743 | Methyl Parathion | Methyl Parathion results in increased expression of AKR1C2 mRNA | 19800895 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in increased expression of AKR1C2 protein | 24625837 |
| D009281 | Naphthalenes | AKR1C2 protein results in increased reduction of and affects the activity of Naphthalenes | 21910479 |
| D009288 | Naproxen | Naproxen results in decreased activity of AKR1C2 protein | 19010312 |
| C119536 | nickel acetate | nickel acetate affects the expression of AKR1C2 mRNA | 23828170 |
| D009567 | Nitrazepam | Nitrazepam results in decreased activity of AKR1C2 protein | 11995921 |
| C014112 | N-methyl-4-aminophenol | N-methyl-4-aminophenol results in increased activity of AKR1C2 promoter | 21195160 |
| C014112 | N-methyl-4-aminophenol | N-methyl-4-aminophenol results in increased expression of AKR1C2 mRNA | 20491607 |
| C558013 | NSC 689534 | [NSC 689534 binds to Copper] which results in increased expression of AKR1C2 mRNA | 20971185 |
| C025589 | ochratoxin A | ochratoxin A results in decreased expression of AKR1C2 mRNA | 19287073 |
| C016627 | octyl gallate | octyl gallate results in decreased activity of AKR1C2 protein | 27163852 |
| C016340 | o,p'-DDT | "o,p'-DDT results in increased expression of AKR1C2 mRNA" | 18204070 |
| D010081 | Oxazolone | Oxazolone results in increased activity of AKR1C2 promoter | 21195160 |
| C036006 | oxcarbazepine | AKR1C2 protein results in increased reduction of oxcarbazepine | 25063510 |
| D010100 | Oxygen | Oxygen deficiency results in decreased expression of AKR1C2 mRNA | 25596134 |
| D017239 | Paclitaxel | AKR1C2 mRNA results in increased susceptibility to Paclitaxel | 16322897 |
| D052638 | Particulate Matter | [Particulate Matter co-treated with Benzo(a)pyrene] results in increased expression of AKR1C2 mRNA | 17612574 |
| D052638 | Particulate Matter | "[Particulate Matter co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C2 mRNA" | 17612574 |
| C023036 | perfluorooctanoic acid | perfluorooctanoic acid results in decreased expression of AKR1C2 mRNA | 17681415 |
| D020113 | Phenolphthalein | Phenolphthalein results in decreased activity of AKR1C2 protein | 12604236 |
| C013192 | phenylacetaldehyde | phenylacetaldehyde results in increased expression of AKR1C2 mRNA | 20491607 |
| C016050 | phenylglycidyl ether | phenylglycidyl ether analog promotes the reaction [NFE2L2 protein results in increased expression of AKR1C2 mRNA] | 21751775 |
| D010662 | Phenylmercuric Acetate | "[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| D010662 | Phenylmercuric Acetate | Phenylmercuric Acetate results in increased expression of AKR1C2 mRNA | 26272509 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of AKR1C2 mRNA | 18467677 |
| C006253 | pirinixic acid | PPARA protein promotes the reaction [pirinixic acid results in decreased expression of AKR1C2 mRNA] | 18467677 |
| C019536 | potassium bromate | potassium bromate results in increased expression of AKR1C2 mRNA | 23588252 |
| D011278 | Pregnanes | AKR1C2 protein affects the metabolism of Pregnanes metabolite | 12604236 |
| D011280 | Pregnanolone | AKR1C2 protein affects the metabolism of Pregnanolone | 12604236 |
| D011280 | Pregnanolone | AKR1C2 protein results in increased reduction of Pregnanolone | 11995921 |
| D011374 | Progesterone | AKR1C2 protein results in increased reduction of Progesterone | 11158055|2224560 |
| D011374 | Progesterone | Progesterone inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| D011372 | Progestins | AKR1C2 protein results in increased metabolism of Progestins | 22245609 |
| D011435 | Propyl Gallate | Propyl Gallate results in increased expression of AKR1C2 mRNA | 20491607 |
| D015237 | Dinoprost | AKR1C2 protein results in increased metabolism of Dinoprost | 8573067 |
| D011794 | Quercetin | Quercetin results in decreased expression of AKR1C2 mRNA | 21632981 |
| D015125 | Oxyquinoline | Oxyquinoline results in increased expression of AKR1C2 mRNA | 21632981|2619864 |
| C004532 | quinone | quinone results in increased expression of AKR1C2 mRNA | 20491607 |
| D017382 | Reactive Oxygen Species | [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 mRNA | 19320734 |
| D017382 | Reactive Oxygen Species | [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of AKR1C2 protein | 19320734 |
| D017975 | Ruthenium Compounds | Ruthenium Compounds analog inhibits the reaction [[AKR1C2 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol] | 25446855 |
| D020156 | Salicylic Acid | Salicylic Acid results in decreased activity of AKR1C2 protein | 19010312 |
| D020156 | Salicylic Acid | Salicylic Acid results in increased expression of AKR1C2 mRNA | 20491607 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in increased secretion of AKR1C2 protein | 25895662 |
| D012834 | Silver | Silver results in increased expression of AKR1C2 mRNA | 28959546 |
| D012906 | Smoke | Smoke results in increased expression of AKR1C2 mRNA | 21095227 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of AKR1C2 mRNA | 19696165|2088654 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of AKR1C2 protein | 19696165 |
| D012967 | Sodium Dodecyl Sulfate | Sodium Dodecyl Sulfate results in increased expression of AKR1C2 mRNA | 20491607 |
| C016766 | sulforafan | sulforafan results in increased expression of AKR1C2 mRNA | 24383545 |
| D013467 | Sulindac | Sulindac results in decreased activity of AKR1C2 protein | 19010312 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of AKR1C2 mRNA | 15507505 |
| D013739 | Testosterone | Testosterone inhibits the reaction [AKR1C2 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] | 28257955 |
| C004648 | testosterone enanthate | testosterone enanthate affects the expression of AKR1C2 mRNA | 17440010 |
| D013749 | Tetrachlorodibenzodioxin | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of AKR1C2 mRNA | 19619570 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of AKR1C2 mRNA | 19619570 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in decreased expression of AKR1C2 mRNA | 26198647 |
| C009413 | tetrahydrodeoxycorticosterone | AKR1C2 protein affects the oxidation of tetrahydrodeoxycorticosterone | 12604236 |
| C019106 | tetralol | AKR1C2 protein affects the oxidation of tetralol | 12604236 |
| D013893 | Thiram | Thiram results in increased activity of AKR1C2 promoter | 21195160 |
| C009495 | titanium dioxide | titanium dioxide results in decreased phosphorylation of AKR1C2 protein | 21439344 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in increased expression of AKR1C2 mRNA | 22363418|2740439 |
| C012589 | trichostatin A | "[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C012589 | trichostatin A | trichostatin A results in increased expression of AKR1C2 mRNA | 24935251|2627250 |
| D014302 | Trinitrobenzenesulfonic Acid | Trinitrobenzenesulfonic Acid results in increased expression of AKR1C2 mRNA | 25724174 |
| C050414 | tripterine | tripterine results in increased expression of AKR1C2 mRNA | 17010675 |
| C013320 | tris(2-butoxyethyl) phosphate | tris(2-butoxyethyl) phosphate results in decreased expression of AKR1C2 mRNA | 29024780 |
| D014520 | Urethane | Urethane results in decreased expression of AKR1C2 mRNA | 28818685 |
| D014580 | Ursodeoxycholic Acid | Ursodeoxycholic Acid inhibits the reaction [[AKR1C2 protein co-treated with NADP] results in increased reduction of cyclopentanone] | 23261716 |
| D014580 | Ursodeoxycholic Acid | Ursodeoxycholic Acid results in decreased activity of AKR1C2 protein | 12604236|2326171 |
| D014635 | Valproic Acid | [Hydralazine co-treated with Valproic Acid] results in increased expression of AKR1C2 mRNA | 17183730 |
| D014635 | Valproic Acid | "[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of AKR1C2 mRNA | 25979313 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of AKR1C2 gene | 29154799 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of AKR1C2 mRNA | 23179753|2438349 |
| C100058 | vanillin | vanillin results in increased expression of AKR1C2 mRNA | 20491607 |
| D001335 | Vehicle Emissions | [Vehicle Emissions co-treated with Benzo(a)pyrene] results in increased expression of AKR1C2 mRNA | 17612574 |
| D001335 | Vehicle Emissions | "[Vehicle Emissions co-treated with dibenzo(a,l)pyrene] results in increased expression of AKR1C2 mRNA" | 17612574 |
| D014810 | Vitamin E | Vitamin E results in increased expression of AKR1C2 mRNA | 19244175 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in increased expression of AKR1C2 mRNA | 12414654|2341063 |
| C111237 | vorinostat | "[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C2 mRNA" | 27188386 |
| C111237 | vorinostat | vorinostat results in increased expression of AKR1C2 mRNA | 26272509 |
| D019287 | Zinc Sulfate | Zinc Sulfate results in increased expression of AKR1C2 mRNA | 16330358 |
| C088658 | zoledronic acid | zoledronic acid results in decreased expression of AKR1C2 mRNA | 25596134 |
| C020549 | zomepirac | zomepirac results in decreased activity of AKR1C2 protein | 19010312 |