Gene info: ID 1674

Gene: DES

GENE ID: 1674

Description: desmin

Gene type: protein-coding

Location: 2q35

dbXrefs: Ensembl:ENSG00000175084 MIM:125660 Vega:OTTHUMG00000058924 UniprotKB:P17661

RefSeq: NG_008043.1

Retrived from: PubMed

SNPs: 0 ANCO-SNPs

Phenotype: OD|ND|AD

# Publications: 39

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 9.868e-1 (AD) 8.679e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
TNNC1	0.756
MB	0.744
MYL2	0.736
CKM	0.707
MYH7	0.678
ACTG2	0.675
MYH11	0.67
ACTA1	0.668
ACTC1	0.665
ANKRD1	0.659

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
ZNF835	-0.267
MYH7B	-0.264
PNPLA7	-0.262
APOA4	-0.257
HHATL	-0.252
IFNA6	-0.247
FCHO1	-0.244
CDT1	-0.242
ZNF575	-0.241
NEU4	-0.232

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C107946	2,7-dihydroxynaphthalene	"2,7-dihydroxynaphthalene results in decreased expression of DES mRNA"	28940058
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of DES mRNA"	12376462
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of DES mRNA"	23196670
C472791	3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid	3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of DES mRNA	16788091
D000082	Acetaminophen	Acetaminophen affects the expression of DES mRNA	17562736
D000082	Acetaminophen	Acetaminophen results in increased expression of DES mRNA	15800402
D000082	Acetaminophen	Acetaminophen results in increased expression of DES protein	15800402
C464485	acetamiprid	acetamiprid results in decreased expression of DES mRNA	27782041
D019342	Acetic Acid	Acetic Acid affects the expression of DES protein	21296659
C056165	acetovanillone	acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
C056165	acetovanillone	acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D000171	Acrolein	Acrolein affects the metabolism of DES protein	17921335
D020106	Acrylamide	Acrylamide results in decreased expression of DES mRNA	28959563
C526957	alisol B 23-acetate	alisol B 23-acetate inhibits the reaction [AGT protein results in increased expression of DES protein]	28578904
D006710	Homocysteine	acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
D006710	Homocysteine	acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D006710	Homocysteine	Amitriptyline inhibits the reaction [Homocysteine results in increased expression of DES protein]	23024785
D006710	Homocysteine	CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA]	20116427
D006710	Homocysteine	diphenyleneiodonium inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
D006710	Homocysteine	diphenyleneiodonium inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D006710	Homocysteine	Filipin inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
D006710	Homocysteine	Filipin inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D006710	Homocysteine	[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA	20116427
D006710	Homocysteine	Homocysteine results in increased expression of DES mRNA	20036696
D006710	Homocysteine	Homocysteine results in increased expression of DES protein	20036696\|2302478
D006710	Homocysteine	methyl-beta-cyclodextrin inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
D006710	Homocysteine	methyl-beta-cyclodextrin inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D000639	Amitriptyline	Amitriptyline inhibits the reaction [Homocysteine results in increased expression of DES protein]	23024785
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of DES mRNA	16483693
D000643	Ammonium Chloride	Ammonium Chloride results in decreased expression of DES protein	16483693
D016718	Arachidonic Acid	Arachidonic Acid results in increased expression of DES mRNA	19089455
D001374	Azacitidine	Azacitidine results in increased expression of DES mRNA	20823114
D001374	Azacitidine	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA	20823114
D001374	Azacitidine	Azacitidine results in increased expression of DES mRNA	18037191
D001374	Azacitidine	Azacitidine results in increased expression of DES protein	18037191
C044946	benazepril	benazepril results in decreased expression of DES mRNA	20137276
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of DES mRNA	22228805
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of DES mRNA	21839799
D004958	Estradiol	Estradiol results in increased expression of DES protein	28947387
D004958	Estradiol	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA	20823114
D004958	Estradiol	[Progesterone co-treated with Estradiol] results in decreased expression of DES mRNA	18692832
D004958	Estradiol	Estradiol results in decreased expression of DES mRNA	19484750
D004958	Estradiol	[Estradiol co-treated with Progesterone] results in increased expression of DES mRNA	19089455
C002791	bismuth tripotassium dicitrate	bismuth tripotassium dicitrate results in decreased expression of DES mRNA	15912405
C006780	bisphenol A	bisphenol A results in increased expression of DES protein	28947387
C006780	bisphenol A	bisphenol A results in increased expression of DES mRNA	24090592
C006780	bisphenol A	bisphenol A results in decreased expression of DES mRNA	27178563
C006780	bisphenol A	bisphenol A results in decreased expression of DES protein	20219716
C006780	bisphenol A	bisphenol A results in increased expression of DES mRNA	25181051
C005961	bis(tri-n-butyltin)oxide	bis(tri-n-butyltin)oxide results in increased phosphorylation of DES protein	22174045
D001761	Bleomycin	Bleomycin results in increased expression of DES protein	25933445
C032688	boric acid	boric acid affects the expression of DES mRNA	25637568
C487049	BXL628	BXL628 results in decreased expression of DES mRNA	16003237
D002104	Cadmium	Cadmium results in increased oxidation of DES protein	24077948
D019256	Cadmium Chloride	Cadmium Chloride results in increased expression of DES mRNA	24982889
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of DES protein	14739096\|2556682
D002251	Carbon Tetrachloride	[Tetrachlorodibenzodioxin co-treated with Carbon Tetrachloride] results in increased expression of DES mRNA	27693115
D002251	Carbon Tetrachloride	Carbon Tetrachloride affects the expression of DES protein	23262250
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of DES mRNA	15728706
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of DES protein	17030452
D002251	Carbon Tetrachloride	resveratrol inhibits the reaction [Carbon Tetrachloride affects the expression of DES protein]	23262250
D002251	Carbon Tetrachloride	Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of DES protein]	17030452
D000068579	Celecoxib	Celecoxib results in increased expression of DES mRNA	18089846
D000068579	Celecoxib	PTGS2 protein affects the reaction [Celecoxib results in increased expression of DES mRNA]	18089846
D004002	Clodronic Acid	[Clodronic Acid co-treated with Thioacetamide] results in increased expression of DES protein	26957569
D002994	Clofibrate	Clofibrate results in decreased expression of DES mRNA	22300585
D016572	Cyclosporine	Cyclosporine results in decreased expression of DES protein	19540300
D003630	Daunorubicin	Daunorubicin results in increased expression of DES mRNA	27816693
D064791	Desoxycorticosterone Acetate	[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of DES protein	21992601
C042577	diallyl trisulfide	diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein]	28157488
C042577	diallyl trisulfide	diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of DES protein]	28157488
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of DES mRNA	24893172
D003994	Bucladesine	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA	20823114
D003994	Bucladesine	[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of DES mRNA	19089455
D004041	Dietary Fats	Dietary Fats results in increased expression of DES mRNA	24508291
D004041	Dietary Fats	PYCARD gene mutant form inhibits the reaction [Dietary Fats results in increased expression of DES mRNA]	24508291
D015127	9,10-Dimethyl-1,2-benzanthracene	"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DES mRNA"	12376462
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
C007517	diphenyleneiodonium	diphenyleneiodonium inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D004237	Diuron	Diuron results in decreased expression of DES mRNA	21551480
D004237	Diuron	Diuron results in increased expression of DES mRNA	21551480
D004317	Doxorubicin	Doxorubicin results in decreased expression of DES mRNA	28940058
D004317	Doxorubicin	CSF3 protein inhibits the reaction [Doxorubicin results in decreased expression of DES protein]	17334414
D004317	Doxorubicin	Doxorubicin affects the localization of DES protein	15811867
D004317	Doxorubicin	Doxorubicin results in decreased expression of DES protein	16449733\|1733441
D004317	Doxorubicin	EPO protein inhibits the reaction [Doxorubicin results in decreased expression of DES protein]	16449733
D004317	Doxorubicin	Sildenafil Citrate inhibits the reaction [Doxorubicin affects the localization of DES protein]	15811867
D004317	Doxorubicin	Doxorubicin results in increased expression of DES protein	11014987
C013525	ENNG	[ENNG co-treated with Isoflavones] results in increased expression of DES protein	22248470
C013525	ENNG	ENNG results in increased expression of DES protein	22248470
D004837	Epinephrine	[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of DES protein	19464573
D004837	Epinephrine	Epinephrine results in decreased expression of DES protein	19464573
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of DES mRNA	24096037
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of DES mRNA	12655037\|1557682
C026098	etiracetam	etiracetam results in increased expression of DES mRNA	20345932
D005372	Filipin	Filipin inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
D005372	Filipin	Filipin inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of DES mRNA	17187413
D005472	Fluorouracil	Fluorouracil results in decreased expression of DES protein	21296659
D005492	Folic Acid	CYBB protein mutant form inhibits the reaction [[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA]	20116427
D005492	Folic Acid	[Folic Acid deficiency results in increased abundance of Homocysteine] which results in increased expression of DES mRNA	20116427
D005492	Folic Acid	Folic Acid deficiency results in increased expression of DES protein	21893018
C039281	furan	furan results in increased expression of DES mRNA	27387713
D006493	Heparin	Heparin results in decreased expression of DES protein	9111513
D017313	Fenretinide	Fenretinide results in increased expression of DES mRNA	28973697
D006861	Hydrogen Peroxide	Hydrogen Peroxide affects the expression of DES protein	21179406
C492448	ICG 001	ICG 001 inhibits the reaction [AGT protein results in increased expression of DES protein]	28578904
D007529	Isoflavones	[ENNG co-treated with Isoflavones] results in increased expression of DES protein	22248470
C561695	(+)-JQ1 compound	(+)-JQ1 compound results in decreased expression of DES mRNA	26644586
D019808	Losartan	Losartan inhibits the reaction [AGT protein results in increased expression of DES protein]	28578904
D017258	Medroxyprogesterone Acetate	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate co-treated with Azacitidine] results in increased expression of DES mRNA	20823114
D017258	Medroxyprogesterone Acetate	[Medroxyprogesterone Acetate co-treated with Bucladesine] results in increased expression of DES mRNA	19089455
D008727	Methotrexate	Methotrexate results in increased expression of DES protein	8667468
C108732	methyl-beta-cyclodextrin	methyl-beta-cyclodextrin inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	20036696
C108732	methyl-beta-cyclodextrin	methyl-beta-cyclodextrin inhibits the reaction [Homocysteine results in increased expression of DES protein]	20036696
D009173	Mycophenolic Acid	Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]	17624267
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in increased expression of DES mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in increased expression of DES mRNA"	25554681
C031721	naphthalene	naphthalene metabolite binds to DES protein	16453347
D009532	Nickel	Nickel results in decreased expression of DES mRNA	24768652\|2558310
C007350	nitrofen	nitrofen results in decreased expression of DES mRNA	27651373
C007350	nitrofen	nitrofen results in decreased expression of DES protein	27651373
C002741	N-nitrosomorpholine	N-nitrosomorpholine results in decreased expression of DES protein	19716841
C572573	N-nitroso-tris-chloroethylurea	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DES mRNA	27935865
C025256	nonylphenol	nonylphenol results in decreased expression of DES mRNA	22982499
C025256	nonylphenol	nonylphenol results in increased expression of DES protein	19260726
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of DES mRNA"	24096037
C016340	o,p'-DDT	"o,p'-DDT results in increased expression of DES mRNA"	24096037
D010100	Oxygen	diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein]	28157488
D010100	Oxygen	[Oxygen deficiency co-treated with Oxygen] results in decreased expression of DES protein	28157488
D010100	Oxygen	Oxygen results in increased expression of DES mRNA	22911455
C102487	pachymic acid	pachymic acid analog inhibits the reaction [AGT protein results in increased expression of DES protein]	28578904
D010578	Petroleum	Petroleum affects the expression of DES mRNA	25208076
C060836	pioglitazone	[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DES mRNA	27935865
C006253	pirinixic acid	pirinixic acid results in decreased expression of DES mRNA	17426115
D010936	Plant Extracts	Plant Extracts results in decreased expression of DES mRNA	23557933
D011374	Progesterone	[Progesterone co-treated with Estradiol] results in decreased expression of DES mRNA	18692832
D011374	Progesterone	Progesterone results in decreased expression of DES mRNA	18070364
D011374	Progesterone	Progesterone results in increased expression of DES mRNA	19690047
D011374	Progesterone	[Estradiol co-treated with Progesterone] results in increased expression of DES mRNA	19089455
D011374	Progesterone	Progesterone results in increased expression of DES mRNA	20726854
C009055	propargylglycine	diallyl trisulfide inhibits the reaction [propargylglycine results in decreased expression of DES protein]	28157488
C009055	propargylglycine	propargylglycine results in decreased expression of DES protein	28157488
D011692	Puromycin Aminonucleoside	Puromycin Aminonucleoside results in increased expression of DES protein	18509322\|2183627
D011692	Puromycin Aminonucleoside	triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein]	18509322
C059514	resveratrol	resveratrol inhibits the reaction [Carbon Tetrachloride affects the expression of DES protein]	23262250
C041376	rosmarinic acid	rosmarinic acid inhibits the reaction [TGFB1 protein results in increased expression of DES protein]	28789951
D012643	Selenium	Selenium results in increased expression of DES mRNA	19244175
D000068677	Sildenafil Citrate	Sildenafil Citrate inhibits the reaction [Doxorubicin affects the localization of DES protein]	15811867
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of DES mRNA	22431001
C016104	sodium bichromate	sodium bichromate results in decreased expression of DES mRNA	22155349\|2256133
C016104	sodium bichromate	sodium bichromate results in increased expression of DES mRNA	22561333
D012965	Sodium Chloride	[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of DES protein	21992601
D012969	Sodium Fluoride	Sodium Fluoride results in decreased expression of DES protein	28918527
D012999	Soman	Soman results in increased expression of DES mRNA	19281266
D013311	Streptozocin	Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]	17624267
D013311	Streptozocin	Streptozocin results in increased expression of DES protein	12197670\|1762426
D013311	Streptozocin	Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein]	17624267
C016766	sulforafan	DES protein binds to sulforafan	21838287
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of DES mRNA	21570461
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Carbon Tetrachloride] results in increased expression of DES mRNA	27693115
D013792	Thalidomide	Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of DES protein]	17030452
D013853	Thioacetamide	[Clodronic Acid co-treated with Thioacetamide] results in increased expression of DES protein	26957569
D013853	Thioacetamide	Thioacetamide results in increased expression of DES mRNA	23411599
D013853	Thioacetamide	Thioacetamide results in increased expression of DES protein	26957569
C009495	titanium dioxide	titanium dioxide results in decreased expression of DES mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased expression of DES mRNA	18087596
D014212	Tretinoin	Tretinoin results in increased expression of DES mRNA	17069765
C012589	trichostatin A	trichostatin A results in decreased expression of DES protein	12445420
C001899	triptolide	triptolide inhibits the reaction [Puromycin Aminonucleoside results in increased expression of DES protein]	18509322
C022884	undecane	undecane results in increased expression of DES protein	17337753
D014635	Valproic Acid	Valproic Acid results in increased methylation of DES gene	29154799
D000068756	Valsartan	Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein]	17624267
C025643	vinclozolin	vinclozolin results in decreased expression of DES mRNA	23034163
D014810	Vitamin E	Vitamin E results in increased expression of DES mRNA	19244175
D014874	Water Pollutants, Chemical	"Water Pollutants, Chemical affects the expression of DES mRNA"	25208076
D019820	Xanthine	[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of DES protein	19464573
D019820	Xanthine	[Xanthine co-treated with XDH protein] results in decreased expression of DES protein	19464573

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005200	structural constituent of cytoskeleton	-	TAS	9736733
GO:0005515	protein binding	-	IPI	11353857 11581269 16923132 20706999 21135508 23414517 23615443 25416956 26816005 26871637 27107012 27733623 28470624
GO:0008092	cytoskeletal protein binding	-	IPI	11309420
GO:0042802	identical protein binding	-	IPI	21135508

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006936	muscle contraction	-	TAS	9697706
GO:0007010	cytoskeleton organization	-	TAS	9736733
GO:0008016	regulation of heart contraction	-	TAS	9697706
GO:0030049	muscle filament sliding	-	TAS	-
GO:0045109	intermediate filament organization	-	IMP	24200904 26724190

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005634	nucleus	-	ISS	-
GO:0005829	cytosol	-	TAS	-
GO:0005882	intermediate filament	-	IEA	-
GO:0005916	fascia adherens	-	IEA	-
GO:0014704	intercalated disc	-	IDA	24200904 26724190
GO:0030018	Z disc	-	IDA	9415431 24200904 26724190
GO:0031594	neuromuscular junction	-	IEA	-
GO:0042383	sarcolemma	-	IDA	25394388
GO:0045111	intermediate filament cytoskeleton	-	IDA	-
GO:0070062	extracellular exosome	-	HDA	23533145
GO:0097512	cardiac myofibril	-	IDA	25771144

KEGG ID	KEGG Term
hsa05410	Hypertrophic cardiomyopathy (HCM)
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414	Dilated cardiomyopathy

Reactome ID	Reactome Term	Evidence
R-HSA-390522	Striated Muscle Contraction	TAS
R-HSA-397014	Muscle contraction	TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal
7784713	Preliminary evidence that augmentation therapy diminishes degradation of cross-linked elastin in alpha-1-antitrypsin-deficient humans. (1995)	Stone PJ	Respiration
26849144	Effects of cigarette smoking on platelet reactivity during P2Y12 inhibition in patients with myocardial infarction undergoing drug-eluting stent implantation: results from the prospective cigarette smoking on platelet reactivity (COPTER) study. (2016 May)	Patti G	J Thromb Thrombolysis
2008995	Gcglobulin functions as a cochemotaxin in the lower respiratory tract. A potential mechanism for lung neutrophil recruitment in cigarette smokers. (1991 Apr)	Metcalf JP	Am Rev Respir Dis
24669857	Nicotine exaggerates LPS-induced airway hyperreactivity via JNK-mediated up-regulation of Toll-like receptor 4. (2014 Sep)	Xu Y	Am J Respir Cell Mol Biol
7697272	Elastin and collagen degradation products in urine of smokers with and without chronic obstructive pulmonary disease. (1995 Apr)	Stone PJ	Am J Respir Crit Care Med
26079998	Serum fetuin-A levels and abdominal aortic calcification in healthy men - The STRAMBO study. (2015 Oct)	Schoppet M	Bone
22293417	Changes of ghrelin and leptin levels in plasma by cigarette smoke in rats. (2012 Feb)	Tomoda K	J Toxicol Sci
19041092	Plasma des-acyl ghrelin, but not plasma HMW adiponectin, is a useful cardiometabolic marker for predicting atherosclerosis in elderly hypertensive patients. (2009 Jun)	Yano Y	Atherosclerosis
26990518	Rate and Predisposing Factors for Sacroiliac Joint Radiographic Progression After a Two-Year Follow-up Period in Recent-Onset Spondyloarthritis. (2016 Aug)	Dougados M	Arthritis Rheumatol
24694769	Cilostazol eliminates adverse smoking outcome in patients with drug-eluting stent implantation. (2014)	Kim HL	Circ J
25534551	[COPD: Patients speak to doctors. Survey from the Federation francaise des associations et amicales de malades insuffisants ou handicapes respiratoires (FFAAIR)]. (2015 May)	Jebrak G	Rev Mal Respir
16449516	Multiple predictors of coronary restenosis after drug-eluting stent implantation in patients with diabetes. (2006 Aug)	Hong SJ	Heart
26621000	[Relationship between primary lung cancer and tobacco consumption. Results of the KBP-2010-CPHG study by the French College of General Hospital Respiratory Physicians]. (2016 Sep)	Coetmeur D	Rev Mal Respir
26184866	Association of osteoprotegerin with peripheral artery disease in patients with type 2 diabetes. (2015 Aug-Sep)	Esteghamati A	Arch Cardiovasc Dis
16023189	Risk factors for alcohol use among male adolescents and emerging adults in Haiti. (2006 Apr)	Gage AJ	J Adolesc
8630312	The effect of oestrogen dose and progestogen type on haemostatic changes in women taking low dose oral contraceptives. (1996 Mar)	Norris LA	Br J Obstet Gynaecol
8912738	Urinary desmosine excretion in smokers with and without rapid decline of lung function: the Normative Aging Study. (1996 Nov)	Gottlieb DJ	Am J Respir Crit Care Med
25647458	Role of red blood cell distribution in predicting drug-eluting stent restenosis in patients with stable angina pectoris after coronary stenting. (2015 May)	Zhao K	Coron Artery Dis
18025295	Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema. (2008 Jan)	Byrd JB	Hypertension
26718593	Epidemiology of multiple sclerosis. (2016 Jan)	Leray E	Rev Neurol (Paris)
2487974	An enzyme-linked immunosorbent assay (ELISA) for the quantitation of urinary desmosine. (1989 Sep)	Watanabe T	Tokai J Exp Clin Med
28848880	Free Urinary Desmosine and Isodesmosine as COPD Biomarkers: The Relevance of Confounding Factors. (2016 Mar 1)	Ongay S	Chronic Obstr Pulm Dis
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