Gene: C6orf118

168090
bA85G2.1|dJ416F21.2
chromosome 6 open reading frame 118
protein-coding
6q27
Ensembl:ENSG00000112539 Vega:OTTHUMG00000015984 UniprotKB:Q5T5N4
NC_000006.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.627e-1 (AD)  4.329e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DLEC10.578
PARD30.572
LRRC340.56
C3orf700.551
GMPR0.541
CC2D2A0.541
ARHGEF60.54
TMEM1000.534
PYGO10.534
GRAMD1C0.532

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IGFBP2-0.387
MSC-0.384
PHOSPHO1-0.378
CYP26A1-0.371
ADTRP-0.371
TRABD2A-0.364
ABCC12-0.362
DUSP27-0.356
ADRA1D-0.354
HRK-0.352

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of C6ORF118 gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of C6ORF118 mRNA24449571
D001151ArsenicArsenic affects the methylation of C6ORF118 gene25304211
C006780bisphenol Abisphenol A results in decreased expression of C6ORF118 mRNA25181051
D002117CalcitriolCalcitriol results in increased expression of C6ORF118 mRNA16002434
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of C6ORF118 mRNA28001369

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28355295Risk prediction of pulmonary tuberculosis using genetic and conventional risk factors in adult Korean population. (2017)Hong EPPLoS One