Gene: DDX53

168400
CAGE|CT26
DEAD-box helicase 53
protein-coding
Xp22.11
Ensembl:ENSG00000184735 Vega:OTTHUMG00000021248 UniprotKB:Q86TM3
NG_021439.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PRDM140.871
TAS2R410.866
OR56A40.84
PRAMEF170.839
OR9Q20.834
TAS2R300.832
POU5F20.83
OR10K10.829
MTRNR2L50.82
MEOX10.815

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CENPH-0.291
HDDC3-0.287
NPM3-0.275
CLDND2-0.273
CCL27-0.264
CLEC11A-0.263
C1orf50-0.249
SURF2-0.247
LIPJ-0.242
B9D2-0.241

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of DDX53 mRNA24449571
D016190CarboplatinDDX53 gene SNP affects the susceptibility to Carboplatin26378035
C056507gemcitabineDDX53 gene SNP affects the susceptibility to gemcitabine26378035
C568376MT19c compoundMT19c compound results in decreased expression of DDX53 mRNA21781307
D010936Plant ExtractsPlant Extracts results in decreased expression of DDX53 mRNA23557933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003723RNA binding-IEA-  
GO:0005524ATP binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24453033Detection of circulating antibodies to linear peptide antigens derived from ANXA1 and DDX53 in lung cancer. (2014 May)Wang WTumour Biol