Gene: FAM9B

171483
TEX39B
family with sequence similarity 9 member B
protein-coding
Xp22.31
Ensembl:ENSG00000177138 MIM:300478 Vega:OTTHUMG00000021114 UniprotKB:Q8IZU0
NC_000023.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ELSPBP10.701
SIM10.696
HMX30.693
OTP0.685
FOXB10.685
C22orf420.674
LHX50.673
HMX20.672
SIX60.671
NTS0.663

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NXPH3-0.279
ZBTB12-0.276
MGLL-0.274
ARSE-0.254
SCRT1-0.246
TEX29-0.239
CASC10-0.225
NEUROG2-0.224
DDN-0.223
KCNN1-0.222

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of FAM9B mRNA24449571
C005556propionaldehydepropionaldehyde results in increased expression of FAM9B mRNA26079696
D014635Valproic AcidValproic Acid results in increased methylation of FAM9B gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  25910212  26871637  
GO ID GO Term Qualifier Evidence PubMed
GO:0007283spermatogenesis-IBA21873635  
GO:0007286spermatid development-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000795synaptonemal complex-IBA21873635  
GO:0005654nucleoplasm-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21998597Genetic determinants of serum testosterone concentrations in men. (2011 Oct)Ohlsson CPLoS Genet