Gene: DHCR24

1718
DCE|Nbla03646|SELADIN1|seladin-1
24-dehydrocholesterol reductase
protein-coding
1p32.3
Ensembl:ENSG00000116133 MIM:606418 Vega:OTTHUMG00000009989 UniprotKB:Q15392
NG_008839.1
PubMed
0   ANCO-SNPs
ND
3   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.488e-1 (AD)  3.874e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
KIFAP30.948
RTN10.941
MAP2K50.94
TSPAN50.94
WDR70.939
GOT10.939
TMEM2460.939
DYNC1I10.939
PCMT10.938
TRIM30.937

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
RNF135-0.489
MTRNR2L10-0.487
MTRNR2L6-0.485
OR4F5-0.483
ASB4-0.476
MTRNR2L9-0.474
KCNJ15-0.456
IL18RAP-0.455
CXCR2-0.454
OR4F29-0.453

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5550191-(1-(4-fluorophenyl)ethyl)-3-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)methylene)-2-piperidinone1-(1-(4-fluorophenyl)ethyl)-3-((3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)methylene)-2-piperidinone results in decreased activity of DHCR24 protein24085193
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased expression of DHCR24 mRNA"22101211
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of DHCR24 mRNA"22101211
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of DHCR24 mRNA28329830
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of DHCR24 mRNA"25305463
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of DHCR24 mRNA"20826375
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of DHCR24 mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of DHCR24 mRNA"21346803
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in increased expression of DHCR24 mRNA25088246
C4861844,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol"4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol results in increased expression of DHCR24 mRNA"15585566
C4750936-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime"[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of NR1I3 protein] which results in increased expression of DHCR24 mRNA"22101211
D000082AcetaminophenAcetaminophen results in decreased expression of DHCR24 mRNA29067470
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of DHCR24 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of DHCR24 gene27153756
D000393Air PollutantsAir Pollutants analog results in decreased expression of DHCR24 mRNA21757418
D013196DihydrotestosteroneDihydrotestosterone affects the expression of DHCR24 mRNA17094431
D000638AmiodaroneAmiodarone affects the expression of DHCR24 mRNA19483382
C519728archazolid Barchazolid B results in increased expression of DHCR24 mRNA25218289
D001280AtrazineAtrazine results in decreased expression of DHCR24 mRNA22378314
D001507BeclomethasoneBeclomethasone results in increased expression of DHCR24 mRNA23656298
D001553BenzbromaroneBenzbromarone affects the expression of DHCR24 mRNA19483382
D001554Benzene[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of DHCR24 mRNA17905399
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of DHCR24 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of DHCR24 mRNA20064835|2623829
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of DHCR24 mRNA20504355
C038328BEP protocolBEP protocol results in increased expression of DHCR24 mRNA18987330
D004958EstradiolEstradiol results in decreased expression of DHCR24 mRNA18260696|2337363
D004958EstradiolEstradiol results in increased expression of DHCR24 mRNA15585566
D004958EstradiolEstradiol results in increased expression of DHCR24 mRNA20826375
C006780bisphenol Abisphenol A results in increased expression of DHCR24 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of DHCR24 mRNA20826375
C006780bisphenol Abisphenol A results in increased expression of DHCR24 mRNA25181051
C025703bleomycetinbleomycetin results in decreased expression of DHCR24 mRNA21040473
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of DHCR24 mRNA22079614
C018475butyraldehydebutyraldehyde results in decreased expression of DHCR24 mRNA26079696
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of DHCR24 mRNA23741332
C034939cadmium sulfidecadmium sulfide results in increased expression of DHCR24 mRNA27866839
D002110CaffeineCaffeine results in decreased expression of DHCR24 mRNA20864626
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of DHCR24 mRNA16239168
D000068579CelecoxibCelecoxib affects the expression of DHCR24 mRNA20562220
C026690cerous chloridecerous chloride results in decreased expression of DHCR24 mRNA28954213
C062876cetrorelix[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DHCR24 mRNA18160741
C062876cetrorelix[cetrorelix co-treated with testosterone enanthate] results in decreased expression of DHCR24 mRNA18160741
D002784Cholesterol[DHCR24 protein results in increased metabolism of Desmosterol] which results in increased abundance of Cholesterol23042211
D002784CholesterolDHCR24 protein affects the abundance of Cholesterol19260826
D002793Cholic Acids[Cyclosporine co-treated with Cholic Acids] affects the expression of DHCR24 mRNA27344345
D002922CiguatoxinsCiguatoxins affects the expression of DHCR24 mRNA18353800
D002994ClofibrateClofibrate affects the expression of DHCR24 mRNA19483382
C018021cobaltous chloridecobaltous chloride results in decreased expression of DHCR24 mRNA19320972
C018021cobaltous chloridecobaltous chloride results in decreased expression of DHCR24 mRNA24386269
D003300CopperCopper results in decreased expression of DHCR24 mRNA20020678
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of DHCR24 mRNA20971185
D003300Copper[ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of DHCR24 mRNA15467011
D019327Copper SulfateCopper Sulfate results in decreased expression of DHCR24 mRNA19549813
D003474CurcuminCurcumin affects the expression of DHCR24 mRNA27208389
D003474CurcuminCurcumin results in decreased expression of DHCR24 mRNA27208389
D016572Cyclosporine[Cyclosporine co-treated with Cholic Acids] affects the expression of DHCR24 mRNA27344345
D016572CyclosporineCyclosporine results in decreased expression of DHCR24 mRNA20106945|2556210
D016572CyclosporineCyclosporine results in decreased expression of DHCR24 mRNA19770486
D003561CytarabineCytarabine results in decreased expression of DHCR24 mRNA21198554
C014347decitabinedecitabine affects the expression of DHCR24 mRNA23300844
D003671DEET[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DHCR24 mRNA28659758
D003897DesmosterolDHCR24 protein results in increased metabolism of Desmosterol23042211
D003897Desmosterol[DHCR24 protein results in increased metabolism of Desmosterol] which results in increased abundance of Cholesterol23042211
D003687DehydroepiandrosteroneDehydroepiandrosterone affects the expression of DHCR24 mRNA17094431
D013759DronabinolDronabinol results in decreased expression of DHCR24 mRNA21955143
D017135Desogestrel[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DHCR24 mRNA18160741
D003907DexamethasoneDexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of DHCR24 mRNA]27941970
D003907DexamethasoneDexamethasone results in increased expression of DHCR24 mRNA25047013
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of DHCR24 mRNA28628672
C492519diarylpropionitrilediarylpropionitrile results in increased expression of DHCR24 mRNA15585566
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of DHCR24 mRNA21266533
D002945CisplatinCisplatin affects the expression of DHCR24 mRNA23300844
D002945CisplatinCisplatin promotes the reaction [jinfukang results in increased expression of DHCR24 mRNA]27392435
D002945CisplatinCisplatin results in decreased expression of DHCR24 mRNA27594783
D002945Cisplatinjinfukang promotes the reaction [Cisplatin results in increased expression of DHCR24 mRNA]27392435
D002945CisplatinCisplatin results in increased expression of DHCR24 mRNA21151649
D004008DiclofenacDiclofenac results in increased expression of DHCR24 mRNA26934552
C036042dicyclohexyl phthalatedicyclohexyl phthalate affects the expression of DHCR24 mRNA26924002
D002117CalcitriolCalcitriol results in increased expression of DHCR24 mRNA26485663
C024629dimethyl phthalatedimethyl phthalate affects the expression of DHCR24 mRNA26924002
C051904dinophysistoxin 1dinophysistoxin 1 results in decreased expression of DHCR24 mRNA28939011
D000068538DutasterideDutasteride results in decreased expression of DHCR24 mRNA17636412
D000431EthanolEthanol results in increased expression of DHCR24 mRNA19167417|2195514
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of DHCR24 mRNA17351261
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of DHCR24 mRNA17108234
D005001EthionineEthionine affects the expression of DHCR24 mRNA19483382
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of DHCR24 mRNA23649840
D005228Fatty Acids, Essential"Fatty Acids, Essential deficiency results in increased expression of DHCR24 mRNA"23333450
D005411Flame RetardantsFlame Retardants results in decreased expression of DHCR24 mRNA19858236
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in decreased expression of DHCR24 mRNA28329830
C007738fluoranthenefluoranthene results in decreased expression of DHCR24 mRNA28329830
D005557FormaldehydeFormaldehyde results in decreased expression of DHCR24 mRNA23649840
C039281furanfuran results in increased methylation of DHCR24 gene22079235
D019833GenisteinGenistein results in decreased expression of DHCR24 mRNA15378649
D005897GlafenineGlafenine results in increased expression of DHCR24 mRNA24136188
D006046Gold[Polyethyleneimine binds to Gold] which results in decreased expression of DHCR24 mRNA28433809
D006046Gold[Gold co-treated with Polyethylene Glycols] results in decreased expression of DHCR24 mRNA19695318
D017313FenretinideFenretinide results in decreased expression of DHCR24 mRNA28973697
C492448ICG 001ICG 001 results in decreased expression of DHCR24 mRNA26191083
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of DHCR24 mRNA28628672
D007213IndomethacinIndomethacin results in increased expression of DHCR24 mRNA28201806
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DHCR24 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of DHCR24 mRNA28628672
D007545IsoproterenolIsoproterenol results in decreased expression of DHCR24 mRNA20003209
C544151jinfukangCisplatin promotes the reaction [jinfukang results in increased expression of DHCR24 mRNA]27392435
C544151jinfukangjinfukang promotes the reaction [Cisplatin results in increased expression of DHCR24 mRNA]27392435
C544151jinfukangjinfukang results in increased expression of DHCR24 mRNA27392435
C045463leflunomideleflunomide results in increased expression of DHCR24 mRNA24136188
C052901lemongrass oillemongrass oil affects the expression of DHCR24 mRNA25976427
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in increased expression of DHCR24 mRNA"24972896
D008154LucanthoneLucanthone results in increased expression of DHCR24 mRNA21148553
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of DHCR24 mRNA26378955
D008752Methylene ChlorideMethylene Chloride affects the expression of DHCR24 mRNA28392392
C030957methylmercury II[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of DHCR24 mRNA17905399
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of DHCR24 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of DHCR24 mRNA23649840
C008493methylselenic acidAR protein inhibits the reaction [methylselenic acid results in decreased expression of DHCR24 mRNA]16020662
C008493methylselenic acidmethylselenic acid results in decreased expression of DHCR24 mRNA16020662|1854812
D008777MethyltestosteroneMethyltestosterone results in increased expression of DHCR24 mRNA29191790
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of DHCR24 mRNA23360888
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of DHCR24 protein24625837
C517284monomethyl phthalatemonomethyl phthalate affects the expression of DHCR24 mRNA26924002
D009020MorphineMorphine results in decreased expression of DHCR24 mRNA21955143
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of DHCR24 mRNA"29244179
D000068577NebivololNebivolol results in increased expression of DHCR24 mRNA17467819
C022838nickel chloridenickel chloride results in decreased expression of DHCR24 mRNA17312168
C022838nickel chloridenickel chloride affects the expression of DHCR24 mRNA22110744
D009538NicotineNicotine results in decreased expression of DHCR24 mRNA21955143
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of DHCR24 mRNA20971185
C025589ochratoxin Aochratoxin A results in decreased expression of DHCR24 mRNA23358140
D009853OmeprazoleOmeprazole affects the expression of DHCR24 mRNA19483382
D010100OxygenOxygen deficiency results in decreased expression of DHCR24 mRNA26516004
D010100OxygenOxygen results in decreased expression of DHCR24 mRNA27103661
D017239PaclitaxelDHCR24 protein affects the susceptibility to Paclitaxel16217747
D010269ParaquatParaquat results in decreased expression of DHCR24 mRNA23315990
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of DHCR24 mRNA19858236
C046012pentanalpentanal results in decreased expression of DHCR24 mRNA26079696
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of DHCR24 protein26879310
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of DHCR24 mRNA27614199
D026023Permethrin[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DHCR24 mRNA28659758
D010634PhenobarbitalPhenobarbital affects the expression of DHCR24 mRNA23091169
D010795Phthalic AcidsPhthalic Acids results in increased expression of DHCR24 mRNA21061450
C006253pirinixic acidpirinixic acid results in increased expression of DHCR24 mRNA20813756
C006253pirinixic acidpirinixic acid affects the expression of DHCR24 mRNA19483382
D011092Polyethylene Glycols[Gold co-treated with Polyethylene Glycols] results in decreased expression of DHCR24 mRNA19695318
D011094Polyethyleneimine[Polyethyleneimine binds to Gold] which results in decreased expression of DHCR24 mRNA28433809
D011137PolystyrenesPolystyrenes analog results in decreased expression of DHCR24 mRNA25102311
D011192Potassium DichromatePotassium Dichromate results in increased expression of DHCR24 protein23718831
D011441PropylthiouracilPropylthiouracil affects the expression of DHCR24 mRNA19483382
D011441PropylthiouracilPropylthiouracil results in decreased expression of DHCR24 mRNA24780913
D011729Pyridostigmine Bromide[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of DHCR24 mRNA28659758
D011794QuercetinQuercetin results in decreased expression of DHCR24 mRNA21632981
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in decreased expression of DHCR24 mRNA15585566
D015474IsotretinoinIsotretinoin results in decreased expression of DHCR24 mRNA20436886
D012293Rifampin[Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA22101211
D020845Selective Estrogen Receptor ModulatorsSelective Estrogen Receptor Modulators results in increased expression of DHCR24 mRNA15585566
D012643SeleniumSelenium results in increased expression of DHCR24 mRNA19244175
C002979selenomethylselenocysteineselenomethylselenocysteine results in decreased expression of DHCR24 mRNA19025659
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of DHCR24 mRNA23806026|2589566
D012822Silicon DioxideSilicon Dioxide results in increased expression of DHCR24 mRNA23623845
D019821SimvastatinSimvastatin results in increased expression of DHCR2421987590
D019821SimvastatinSimvastatin results in increased expression of DHCR24 mRNA21987590
D019821SimvastatinSimvastatin results in increased expression of DHCR24 protein21987590
D019821SimvastatinSimvastatin results in increased expression of DHCR24 mRNA25055962
D012906SmokeSmoke affects the expression of DHCR24 mRNA23693141
C009277sodium arsenatesodium arsenate results in decreased expression of DHCR24 mRNA23922661
C016104sodium bichromatesodium bichromate results in decreased expression of DHCR24 mRNA24612858
D053260SootSoot results in increased expression of DHCR24 mRNA22461453
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of DHCR24 mRNA26378955
C025462sulindac sulfidesulindac sulfide results in decreased expression of DHCR24 mRNA16184548
D016559TacrolimusTacrolimus results in decreased expression of DHCR24 mRNA25270620
C004648testosterone enanthate[cetrorelix co-treated with testosterone enanthate co-treated with Desogestrel] results in decreased expression of DHCR24 mRNA18160741
C004648testosterone enanthate[cetrorelix co-treated with testosterone enanthate] results in decreased expression of DHCR24 mRNA18160741
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of DHCR24 mRNA17555868
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to DHCR24 gene]28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of DHCR24 mRNA28213091
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of DHCR24 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of DHCR24 mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DHCR24 mRNA25613284
D019284ThapsigarginThapsigargin results in decreased expression of DHCR24 mRNA22378314
D013849ThimerosalThimerosal results in decreased expression of DHCR24 mRNA27188386
D013853ThioacetamideThioacetamide affects the expression of DHCR24 mRNA19483382
C009495titanium dioxidetitanium dioxide results in increased expression of DHCR24 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of DHCR24 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of DHCR24 mRNA20133372
C066340tolcaponetolcapone binds to DHCR24 protein19783845
C066340tolcaponetolcapone results in increased expression of DHCR24 mRNA24136188
D014212TretinoinTretinoin results in increased expression of DHCR24 mRNA16604517
D014212TretinoinTretinoin results in increased expression of DHCR24 mRNA20488242
D014241Trichloroethylene[Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in decreased expression of DHCR24 mRNA17905399
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of DHCR24 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of DHCR24 mRNA"26179874
D014415TunicamycinTunicamycin results in decreased expression of DHCR24 mRNA22378314
D014635Valproic AcidValproic Acid results in decreased expression of DHCR24 mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in increased expression of DHCR24 mRNA23179753|2438349
D014635Valproic AcidValproic Acid results in decreased expression of DHCR24 mRNA21427059
D014635Valproic AcidValproic Acid results in increased expression of DHCR24 mRNA21427059
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of DHCR24 gene25560391
C025643vinclozolinvinclozolin results in decreased expression of DHCR24 mRNA23034163
C025643vinclozolinvinclozolin results in increased expression of DHCR24 mRNA22570695
C111237vorinostatvorinostat results in decreased expression of DHCR24 mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000246delta24(24-1) sterol reductase activity-IBA21873635  
GO:0000246delta24(24-1) sterol reductase activity-IMP11519011  
GO:0016614oxidoreductase activity, acting on CH-OH group of donors-IEA-  
GO:0016628oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor-IBA21873635  
GO:0016628oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor-IDA11519011  
GO:0019899enzyme binding-IPI15577914  
GO:0042605peptide antigen binding-IPI15577914  
GO:0050614delta24-sterol reductase activity-EXP11519011  
GO:0050660flavin adenine dinucleotide binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006695cholesterol biosynthetic process-IMP11519011  
GO:0006695cholesterol biosynthetic process-ISS-  
GO:0006915apoptotic process-NAS11007892  
GO:0006979response to oxidative stress-IEP11007892  
GO:0007050cell cycle arrest-NAS15577914  
GO:0007265Ras protein signal transduction-IEA-  
GO:0008104protein localization-IEA-  
GO:0008202steroid metabolic process-IBA21873635  
GO:0008285negative regulation of cell proliferation-IEA-  
GO:0009725response to hormone-IEA-  
GO:0009888tissue development-IMP12457401  
GO:0030539male genitalia development-IEA-  
GO:0031639plasminogen activation-IEA-  
GO:0033489cholesterol biosynthetic process via desmosterol-TAS-  
GO:0033490cholesterol biosynthetic process via lathosterol-TAS-  
GO:0042987amyloid precursor protein catabolic process-IEA-  
GO:0043066negative regulation of apoptotic process-IDA15688385  
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-IDA11007892  
GO:0043588skin development-ISS-  
GO:0055114oxidation-reduction process-IMP11519011  
GO:0061024membrane organization-IEA-  
GO:1901214regulation of neuron death-NAS16407971  
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-IEA-  
GO:0005634nucleus-IDA15577914  
GO:0005737cytoplasm-IBA21873635  
GO:0005783endoplasmic reticulum-IDA11007892  
GO:0005789endoplasmic reticulum membrane-NAS11007892  
GO:0005789endoplasmic reticulum membrane-TAS-  
GO:0005829cytosol-IEA-  
GO:0005856cytoskeleton-IEA-  
GO:0016020membrane-HDA19946888  
GO:0016020membrane-IBA21873635  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
hsa00100Steroid biosynthesis
hsa01100Metabolic pathways
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-191273Cholesterol biosynthesisTAS
R-HSA-556833Metabolism of lipidsTAS
R-HSA-6807047Cholesterol biosynthesis via desmosterolTAS
R-HSA-6807062Cholesterol biosynthesis via lathosterolTAS
R-HSA-8957322Metabolism of steroidsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28194238Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study. (2017)Braun KVEClin Epigenetics
29762635An Epigenome-Wide Association Study (EWAS) of Obesity-Related Traits. (2018 May 14)Dhana KAm J Epidemiol
29325019Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation. (2018 Mar 15)Zaghlool SBHum Mol Genet