| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| TRAM1L1 | 0.754 |
| FAIM | 0.745 |
| DTD2 | 0.74 |
| ZFYVE16 | 0.734 |
| PECR | 0.725 |
| LYPLAL1 | 0.721 |
| EIF2D | 0.718 |
| ERMARD | 0.716 |
| TMEM87A | 0.715 |
| NT5DC1 | 0.713 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| OR4F5 | -0.458 |
| OR4F29 | -0.431 |
| RAX2 | -0.389 |
| EPPIN | -0.389 |
| MMP23B | -0.375 |
| NPC1L1 | -0.358 |
| CELSR1 | -0.334 |
| SLC7A9 | -0.333 |
| SLFNL1 | -0.332 |
| CXorf67 | -0.318 |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C031903 | 1-UFT protocol | AGA protein results in decreased susceptibility to 1-UFT protocol | 16734730 |
| C023514 | 2,6-dinitrotoluene | "2,6-dinitrotoluene affects the expression of AGA mRNA" | 21346803 |
| C029370 | 4-toluidine | 4-toluidine results in increased expression of AGA mRNA | 27638505 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of AGA mRNA | 27761495 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of AGA mRNA | 17562736 |
| D020106 | Acrylamide | Acrylamide results in increased expression of AGA mRNA | 28959563 |
| D001280 | Atrazine | Atrazine results in increased expression of AGA mRNA | 25929836 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of AGA mRNA | 21715664 |
| C543008 | bis(4-hydroxyphenyl)sulfone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of AGA mRNA | 28628672 |
| C006780 | bisphenol A | bisphenol A affects the expression of AGA mRNA | 21786754 |
| C006780 | bisphenol A | bisphenol A results in increased expression of AGA mRNA | 25181051 |
| D002211 | Capsaicin | Capsaicin results in decreased expression of AGA mRNA | 16278290 |
| D002220 | Carbamazepine | Carbamazepine affects the expression of AGA mRNA | 25979313 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of AGA mRNA | 23650126 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of AGA mRNA | 19376846 |
| D003300 | Copper | [NSC 689534 binds to Copper] which results in increased expression of AGA mRNA | 20971185 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of AGA mRNA | 20106945|2163298 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of AGA mRNA | 28628672 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of AGA mRNA | 17361019|2126653 |
| C000944 | dicrotophos | dicrotophos results in decreased expression of AGA mRNA | 28302478 |
| D004221 | Disulfiram | Disulfiram results in decreased expression of AGA mRNA | 20530235 |
| D004397 | Fonofos | Fonofos results in decreased methylation of AGA promoter | 22847954 |
| D005839 | Gentamicins | Gentamicins results in increased expression of AGA mRNA | 22061828 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of AGA mRNA | 28628672 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of AGA mRNA | 25613284 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of AGA mRNA | 28628672 |
| D007657 | Ketone Bodies | Ketone Bodies results in increased expression of AGA mRNA | 16807920 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of AGA mRNA | 28001369 |
| D008777 | Methyltestosterone | Methyltestosterone results in decreased expression of AGA mRNA | 29191790 |
| C558013 | NSC 689534 | [NSC 689534 binds to Copper] which results in increased expression of AGA mRNA | 20971185 |
| D010278 | Parathion | Parathion results in decreased methylation of AGA promoter | 22847954 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of AGA mRNA | 19159669 |
| D015125 | Oxyquinoline | Oxyquinoline results in decreased expression of AGA mRNA | 21632981 |
| D015474 | Isotretinoin | Isotretinoin results in decreased expression of AGA mRNA | 20436886 |
| D012715 | Sesame Oil | Sesame Oil results in increased expression of AGA mRNA | 29191790 |
| C017947 | sodium arsenite | sodium arsenite affects the methylation of AGA gene | 28589171 |
| D018038 | Sodium Selenite | Sodium Selenite results in increased expression of AGA mRNA | 18175754 |
| C012568 | terbufos | terbufos results in decreased methylation of AGA promoter | 22847954 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of AGA mRNA | 25975270 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of AGA mRNA | 25613284 |
| D013893 | Thiram | Thiram results in decreased expression of AGA mRNA | 20530235 |
| C066340 | tolcapone | tolcapone results in decreased expression of AGA mRNA | 24136188 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of AGA mRNA | 25979313 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of AGA mRNA | 23179753|2438349 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in increased methylation of AGA gene | 25560391 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in decreased expression of AGA mRNA | 19165385 |
| C111237 | vorinostat | vorinostat results in increased expression of AGA mRNA | 27188386 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0003948 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity | - | IBA | 21873635 |
| GO:0003948 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity | - | IDA | 1281977 |
| GO:0003948 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity | - | IMP | 1904874 |
| GO:0004067 | asparaginase activity | - | IBA | 21873635 |
| GO:0008233 | peptidase activity | - | IEA | - |
| GO:0008798 | beta-aspartyl-peptidase activity | - | IBA | 21873635 |
| GO:0016787 | hydrolase activity | - | IBA | 21873635 |
| GO:0043621 | protein self-association | - | IEA | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0006508 | proteolysis | - | IEA | - |
| GO:0006517 | protein deglycosylation | - | IBA | 21873635 |
| GO:0006517 | protein deglycosylation | - | IDA | 1281977 |
| GO:0006517 | protein deglycosylation | - | IMP | 1904874 |
| GO:0043312 | neutrophil degranulation | - | TAS | - |
| GO:0051604 | protein maturation | - | IBA | 21873635 |
| GO:0051604 | protein maturation | - | IEA | - |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0005576 | extracellular region | - | TAS | - |
| GO:0005615 | extracellular space | - | IDA | 25645918 |
| GO:0005737 | cytoplasm | - | IBA | 21873635 |
| GO:0005764 | lysosome | - | IBA | 21873635 |
| GO:0005764 | lysosome | - | IDA | 8776587 |
| GO:0005783 | endoplasmic reticulum | - | IDA | 8776587 |
| GO:0035578 | azurophil granule lumen | - | TAS | - |
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-HSA-168249 | Innate Immune System | TAS |
| R-HSA-168256 | Immune System | TAS |
| R-HSA-6798695 | Neutrophil degranulation | TAS |
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 21858886 | Performance of third-trimester ultrasound for prediction of small-for-gestational-age neonates and evaluation of contingency screening policies. (2012 May) | Souka AP | Ultrasound Obstet Gynecol |
| 20410909 | Increased cord serum inflammatory markers in small-for-gestational-age neonates. (2011 Jan) | Amarilyo G | J Perinatol |
| 24801236 | Effect of maternal lipid profile, C-peptide, insulin, and HBA1c levels during late pregnancy on large-for-gestational age newborns. (2014 May) | Hou RL | World J Pediatr |
| 20573680 | High prevalence of polycystic ovary syndrome in women born small for gestational age. (2010 Aug) | Melo AS | Hum Reprod |
| 6374904 | Placental growth and fetal/placental weight (F/P) ratios throughout gestation--their relationship to patterns of fetal growth. (1984 Apr) | Molteni RA | Semin Perinatol |
| 18187557 | Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population. (2008 Feb) | Chen D | Carcinogenesis |
| 19900033 | Could alterations in maternal plasma visfatin concentration participate in the phenotype definition of preeclampsia and SGA? (2010 Aug) | Mazaki-Tovi S | J Matern Fetal Neonatal Med |
| 20712903 | Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study. (2010 Aug 16) | Morgan AR | BMC Med Genet |
| 28178350 | Effects of size at birth, childhood growth patterns and growth hormone treatment on leukocyte telomere length. (2017) | Smeets CC | PLoS One |
| 20889672 | Influence of preterm birth and small birth size on serum anti-Mullerian hormone levels in young adult women. (2010 Dec) | Kerkhof GF | Eur J Endocrinol |
| 27576113 | Acute and chronic malnutrition and their predictors in children aged 0-5 years in Sao Tome: a cross-sectional, population-based study. (2016 Nov) | Valente A | Public Health |
| 16030157 | Smallness for gestational age is associated with persistent change in insulin-like growth factor I (IGF-I) and the ratio of IGF-I/IGF-binding protein-3 in adulthood. (2005 Oct) | Verkauskiene R | J Clin Endocrinol Metab |
| 27795900 | Evaluation of cord blood irisin levels in term newborns with small gestational age and appropriate gestational age. (2016) | Keles E | Springerplus |
| 28503776 | Differences in dietary and lifestyle habits between pregnant women with small fetuses and appropriate-for-gestational-age fetuses. (2017 Jul) | Gomez Roig MD | J Obstet Gynaecol Res |
| 19890342 | Prohepcidin concentrations and erythroid progenitors in cord blood of appropriate versus small for gestational age neonates. (2010 Jun) | Amarilyo G | J Perinatol |
| 29074356 | Anti gliadin antibodies (AGA IgG) related to peripheral inflammation in schizophrenia. (2018 Mar) | Kelly DL | Brain Behav Immun |
| 20930547 | DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age. (2011 Feb) | Tobi EW | Epigenetics |
| 26278975 | Placental 11B-Hydroxysteroid Dehydrogenase Type 2 mRNA Levels in Intrauterine Growth Restriction versus Small-for-Gestational-Age Fetuses. (2016) | Gomez-Roig MD | Fetal Diagn Ther |
| 12775957 | Hair loss, insulin resistance, and heredity in middle-aged women. A population-based study. (2003 Jun) | Matilainen V | J Cardiovasc Risk |
| 26735968 | Implication of the myokine irisin in maternal energy homeostasis in pregnancies with abnormal fetal growth. (2016 Nov) | Briana DD | J Matern Fetal Neonatal Med |
| 1720459 | WISC-test scores at the age of 10 for children born to women with risk pregnancies. (1991) | Lagerstrom M | J Perinat Med |