Gene: DPT

1805
TRAMP
dermatopontin
protein-coding
1q24.2
Ensembl:ENSG00000143196 MIM:125597 Vega:OTTHUMG00000034554 UniprotKB:Q07507
NC_000001.11
PubMed
0   ANCO-SNPs
ND|AD
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.084e-2 (AD)  4.512e-3 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NAAA0.524
DMKN0.518
DSN10.507
TRIM70.506
MARCH90.498
TMEM2430.495
TNNC20.489
PARP20.488
SPAG50.484
LETMD10.483

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANXA13-0.293
TRPV5-0.288
SAMD4A-0.28
OR4F5-0.277
RAI14-0.272
C5orf64-0.269
RBM46-0.267
CHST6-0.261
OR4F29-0.26
GPRC5D-0.258

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Cadmium Chloride results in increased expression of DPT protein]24909373
D000393Air PollutantsAir Pollutants analog results in increased expression of DPT mRNA21757418
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased methylation of DPT gene"26018793
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in increased expression of DPT mRNA"26018793
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of DPT mRNA24449571
D001151ArsenicArsenic affects the methylation of DPT gene25304211
D001280AtrazineAtrazine results in increased expression of DPT mRNA25929836
C547126AZM551248AZM551248 results in increased expression of DPT mRNA22323515
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in decreased expression of DPT mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of DPT mRNA22228805
D004958EstradiolEstradiol results in decreased expression of DPT mRNA19484750
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone results in decreased expression of DPT mRNA27685785
C006780bisphenol Abisphenol A results in decreased expression of DPT mRNA27685785
C006780bisphenol Abisphenol A results in decreased expression of DPT mRNA25181051
D019256Cadmium Chloride4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Cadmium Chloride results in increased expression of DPT protein]24909373
D019256Cadmium ChlorideCadmium Chloride results in increased expression of DPT mRNA24909373
D019256Cadmium ChlorideCadmium Chloride results in increased expression of DPT protein24909373
D019256Cadmium ChlorideDPT mutant form inhibits the reaction [Cadmium Chloride results in decreased expression of CLDN11 protein]24909373
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of DPT mRNA17484886
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of DPT mRNA23650126
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPT mRNA17602206
D003345CorticosteroneCorticosterone results in decreased expression of DPT mRNA15755911
D013759DronabinolDronabinol results in decreased expression of DPT mRNA16616335
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of DPT mRNA28628672
C088674dibromoacetic aciddibromoacetic acid results in decreased expression of DPT mRNA21046364
D004041Dietary FatsDietary Fats results in decreased expression of DPT mRNA18042831
D004041Dietary FatsDietary Fats results in increased expression of DPT mRNA22609946
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DPT mRNA24535843
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of DPT mRNA17602206
D002117CalcitriolCalcitriol results in decreased expression of DPT mRNA26485663
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of DPT mRNA"19480007
D004237DiuronDiuron results in decreased expression of DPT mRNA25152437
D004237DiuronDiuron results in increased expression of DPT mRNA21551480
C118739entinostatentinostat results in increased expression of DPT mRNA27188386
D004785Environmental PollutantsEnvironmental Pollutants results in decreased expression of DPT mRNA20064776
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of DPT mRNA17557909
C004912ethylbenzene[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of DPT gene26018793
C004912ethylbenzene[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of DPT mRNA26018793
D005485FlutamideFlutamide results in increased expression of DPT mRNA24136188
D005492Folic AcidFolic Acid affects the expression of DPT mRNA17320366
C039281furanfuran results in decreased expression of DPT mRNA25539665
C039281furanfuran results in increased methylation of DPT gene22079235
D005839GentamicinsGentamicins results in decreased expression of DPT mRNA22061828
D017313FenretinideFenretinide results in decreased expression of DPT mRNA28973697
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in decreased expression of DPT mRNA"26377693
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of DPT mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of DPT mRNA28628672
C008261lead acetatelead acetate results in decreased expression of DPT mRNA22641619
D009532NickelNickel results in decreased expression of DPT mRNA24768652|2558310
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPT mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DPT mRNA27935865
D010126OzoneOzone results in decreased expression of DPT mRNA12763052
D000073878Palm OilPalm Oil results in decreased expression of DPT mRNA18042831
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of DPT mRNA23602845
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of DPT mRNA24535843
D010656PhenylephrinePhenylephrine results in decreased expression of DPT mRNA18158353
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPT mRNA27935865
C006253pirinixic acidpirinixic acid results in decreased expression of DPT mRNA20813756
D011192Potassium DichromateDPT protein results in decreased susceptibility to Potassium Dichromate24771359
D011192Potassium DichromatePotassium Dichromate results in decreased expression of DPT mRNA24771359
D011374ProgesteroneProgesterone results in increased expression of DPT mRNA22238285
D011441PropylthiouracilPropylthiouracil results in decreased expression of DPT mRNA24780913
C004648testosterone enanthatetestosterone enanthate affects the expression of DPT mRNA17440010
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of DPT mRNA25172293
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of DPT mRNA21889950
C009495titanium dioxidetitanium dioxide results in decreased expression of DPT mRNA23557971
D014050Toluene[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of DPT gene26018793
D014050Toluene[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of DPT mRNA26018793
D014212TretinoinTretinoin results in decreased expression of DPT mRNA23724009
C011559tributyltintributyltin results in increased expression of DPT mRNA21683754
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of DPT mRNA19042947
C406224valdecoxibvaldecoxib results in decreased expression of DPT mRNA24136188
D014635Valproic AcidValproic Acid results in increased expression of DPT mRNA27188386
C025643vinclozolinvinclozolin affects the expression of DPT mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of DPT mRNA23034163
D014810Vitamin EVitamin E results in increased expression of DPT mRNA19244175
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of DPT mRNA27935865
D014992Xylenes[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased methylation of DPT gene26018793
D014992Xylenes[Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased expression of DPT mRNA26018793

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0007155cell adhesion-IEA-  
GO:0008285negative regulation of cell proliferation-IEA-  
GO:0030199collagen fibril organization-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-HDA20551380  
GO:0031012extracellular matrix-IBA21873635  
GO:0062023collagen-containing extracellular matrix-HDA27068509  27559042  
GO:0062023collagen-containing extracellular matrixcolocalizes_withHDA20551380  
GO:0062023collagen-containing extracellular matrixcolocalizes_withISS22261194  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
7749975Natural history of IgE antibodies in children at risk for atopy. (1995 May)Bruno GAnn Allergy Asthma Immunol
25171783Asbestos-related diffuse pleural thickening. (2014)Fujimoto NRespiration