Gene: TSC22D3

1831
DIP|DSIPI|GILZ|TSC-22R
TSC22 domain family member 3
protein-coding
Xq22.3
Ensembl:ENSG00000157514 MIM:300506 Vega:OTTHUMG00000022168 UniprotKB:Q99576
NC_000023.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TSC22D10.819
FAM213A0.793
STARD30.785
RBBP70.784
KLF90.776
PSAP0.772
DKK30.769
SPARCL10.768
PPM1K0.767
WDR450.766

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.646
OR4F29-0.645
KLRB1-0.317
FCRL3-0.311
IL2RB-0.303
TBX21-0.295
KRT73-0.286
MTRNR2L9-0.283
KRT72-0.282
GALR1-0.278

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of TSC22D3 mRNA"18711122
C0264861,2,5,6-dibenzanthracene"[1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of TSC22D3 mRNA"18711122
C0264861,2,5,6-dibenzanthracene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of TSC22D3 mRNA"18711122
C00202917alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol"[17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of TSC22D3 mRNA"17275934
C00202917alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol"17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in increased expression of TSC22D3 mRNA"17275934
C02036517-alpha-hydroxy-progesterone caproate17-alpha-hydroxy-progesterone caproate inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]19255438
C02036517-alpha-hydroxy-progesterone caproate17-alpha-hydroxy-progesterone caproate inhibits the reaction [NR3C1 protein results in increased expression of TSC22D3 mRNA]19255438
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of TSC22D3 mRNA28329830
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of TSC22D3 mRNA19933214
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of TSC22D3 mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of TSC22D3 mRNA"27291303
C0291412,2,5,7,8-pentamethyl-1-hydroxychroman"2,2,5,7,8-pentamethyl-1-hydroxychroman results in decreased expression of TSC22D3 mRNA"21920950
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TSC22D3 mRNA"19167446
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in increased activity of TSC22D3 protein"27589886
C0176183-phenoxybenzoic acid3-phenoxybenzoic acid inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in increased expression of TSC22D3 mRNA"18648102
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of TSC22D3 mRNA19191707
D000082AcetaminophenAcetaminophen affects the expression of TSC22D3 mRNA25064622
D000082AcetaminophenAcetaminophen affects the expression of TSC22D3 mRNA25458485|2570463
D000082AcetaminophenAcetaminophen results in increased expression of TSC22D3 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of TSC22D3 mRNA17562736
C006418adrenocorticotropin zincadrenocorticotropin zinc results in increased expression of TSC22D3 mRNA19920212
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of TSC22D3 mRNA19770486
D000638AmiodaroneAmiodarone affects the expression of TSC22D3 mRNA25064622
D000643Ammonium ChlorideAmmonium Chloride affects the expression of TSC22D3 mRNA16483693
D001151ArsenicArsenic results in increased methylation of TSC22D3 promoter21291286
D001151ArsenicArsenic results in decreased expression of TSC22D3 mRNA19654921
C006632arsenic trioxidearsenic trioxide inhibits the reaction [[DAXX protein binds to NR3C1 protein] which binds to TSC22D3 promoter]17081986
C006632arsenic trioxidearsenic trioxide promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]17081986
C006632arsenic trioxide[Tretinoin co-treated with arsenic trioxide] results in decreased expression of TSC22D3 mRNA15894607
C006632arsenic trioxidearsenic trioxide promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]17081986
C547126AZM551248AZM551248 results in decreased expression of TSC22D3 mRNA22323515
C065857beclomethasone 17-monopropionatebeclomethasone 17-monopropionate results in increased expression of TSC22D3 mRNA23704983
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of TSC22D3 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TSC22D3 mRNA26001963
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of TSC22D3 mRNA19770486|2012785
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of TSC22D3 mRNA21569818
D001564Benzo(a)pyrene"[Benzo(a)pyrene co-treated with 1,2,5,6-dibenzanthracene] affects the expression of TSC22D3 mRNA"18711122
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TSC22D3 mRNA"20382639
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone co-treated with Dexamethasone] results in increased ubiquitination of TSC22D3 protein20671745
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein]]20671745
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone results in increased sumoylation of TSC22D3 protein]20671745
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]20671745
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]20671745
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]20671745
C403753benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketonelactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]20671745
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]20671745
D004958EstradiolESR1 mutant form inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]23183181
D004958Estradiol[Estradiol co-treated with Dexamethasone] inhibits the reaction [NR3C1 protein binds to TSC22D3 promoter]23183181
D004958Estradiol[Estradiol co-treated with Progesterone] results in increased expression of TSC22D3 mRNA20660070
D004958EstradiolEstradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181|2513677
D004958EstradiolEstradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]23183181
D004958EstradiolEstradiol promotes the reaction [ESR1 protein binds to TSC22D3 promoter]23183181
D004958EstradiolEstradiol results in decreased expression of TSC22D3 mRNA23019147|2337363
D004958Estradiolfulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]23183181
D004958Estradiolfulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]23183181
D004958Estradiol[Progesterone co-treated with Estradiol] results in increased expression of TSC22D3 mRNA17404688
D004958EstradiolEstradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]23183181
C095105bexarotenebexarotene results in increased expression of TSC22D3 mRNA17178900
C543008bis(4-hydroxyphenyl)sulfonebis(4-hydroxyphenyl)sulfone affects the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]28916285
C006780bisphenol Abisphenol A affects the methylation of TSC22D3 promoter27334623
C006780bisphenol Abisphenol A results in decreased methylation of TSC22D3 promoter27312807
C006780bisphenol Abisphenol A affects the expression of TSC22D3 mRNA25181051
C006780bisphenol Abisphenol A results in increased expression of TSC22D3 mRNA24988533
D002065BuspironeBuspirone results in increased expression of TSC22D3 mRNA24136188
C018475butyraldehydebutyraldehyde results in increased expression of TSC22D3 mRNA26079696
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of TSC22D3 mRNA27339419
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of TSC22D3 mRNA16934159
D002737ChloropreneChloroprene results in increased expression of TSC22D3 mRNA23125180
D002737ChloropreneChloroprene results in increased expression of TSC22D3 mRNA23125180
D002746ChlorpromazineChlorpromazine affects the expression of TSC22D3 mRNA25064622
D002922CiguatoxinsCiguatoxins affects the expression of TSC22D3 mRNA18353800
C018021cobaltous chloridecobaltous chloride results in decreased expression of TSC22D3 mRNA24386269
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of TSC22D3 mRNA20971185
D003345CorticosteroneCorticosterone results in increased expression of TSC22D3 protein24480152
D003345CorticosteroneTSC22D3 protein affects the reaction [Corticosterone results in decreased susceptibility to Doxorubicin]24480152
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TSC22D3 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in decreased expression of TSC22D3 mRNA19167446
D003375CoumestrolCoumestrol results in decreased expression of TSC22D3 mRNA19167446
D016572CyclosporineCyclosporine affects the expression of TSC22D3 mRNA25064622
D016572CyclosporineCyclosporine results in increased expression of TSC22D3 mRNA25562108|2798913
D016572CyclosporineCyclosporine results in decreased expression of TSC22D3 mRNA19770486
C037304cyhalothrincyhalothrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D003634DDTDDT inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
C014347decitabinedecitabine affects the expression of TSC22D3 mRNA23300844
D003703DemecolcineDemecolcine results in increased expression of TSC22D3 mRNA23649840
D003907Dexamethasone17-alpha-hydroxy-progesterone caproate inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]19255438
D003907Dexamethasonearsenic trioxide promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]17081986
D003907Dexamethasonebis(4-hydroxyphenyl)sulfone affects the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]28916285
D003907DexamethasoneDexamethasone promotes the reaction [NR3C1 protein binds to TSC22D3 promoter]25136773
D003907DexamethasoneDexamethasone results in increased expression of TSC22D3 mRNA17081986|1925543
D003907DexamethasoneDexamethasone results in increased expression of TSC22D3 protein23183181|2513677
D003907Dexamethasone[Dexamethasone results in increased phosphorylation of and results in increased activity of NR3C1 protein] which results in increased expression of TSC22D3 mRNA18483179
D003907DexamethasoneESR1 mutant form inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]23183181
D003907DexamethasoneESR1 mutant form inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]25136773
D003907DexamethasoneESR1 mutant form promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181|2513677
D003907Dexamethasone[Estradiol co-treated with Dexamethasone] inhibits the reaction [NR3C1 protein binds to TSC22D3 promoter]23183181
D003907DexamethasoneEstradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181|2513677
D003907DexamethasoneEstradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]23183181
D003907Dexamethasonefulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]23183181
D003907Dexamethasonefulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]23183181
D003907Dexamethasonefulvestrant inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]25136773
D003907Dexamethasonefulvestrant promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181
D003907DexamethasoneGenistein inhibits the reaction [Dexamethasone promotes the reaction [NR3C1 protein binds to TSC22D3 promoter]]25136773
D003907DexamethasoneGenistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]25136773
D003907DexamethasoneGenistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]25136773
D003907Dexamethasoneliquiritigenin inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181
D003907DexamethasoneNR3C1 mutant form inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]25136773
D003907DexamethasoneTSC22D3 protein affects the reaction [Dexamethasone results in decreased expression of IL5 mRNA]16243713
D003907Dexamethasonearsenic trioxide promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]17081986
D003907Dexamethasone[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone co-treated with Dexamethasone] results in increased ubiquitination of TSC22D3 protein20671745
D003907Dexamethasonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein]]20671745
D003907Dexamethasonebenzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [Dexamethasone results in increased sumoylation of TSC22D3 protein]20671745
D003907Dexamethasone[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]20671745
D003907Dexamethasone[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]20671745
D003907Dexamethasonebenzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]20671745
D003907DexamethasoneCASP8 protein promotes the reaction [Dexamethasone results in increased expression of TSC22D3 protein]20671745
D003907DexamethasoneDexamethasone promotes the reaction [TSC22D3 protein binds to UBE2I protein]20671745
D003907DexamethasoneDexamethasone results in increased expression of TSC22D3 mRNA17998272|1999759
D003907DexamethasoneDexamethasone results in increased expression of TSC22D3 protein20671745|2318318
D003907DexamethasoneDexamethasone results in increased sumoylation of TSC22D3 protein20671745
D003907DexamethasoneEstradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]23183181
D003907Dexamethasonelactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]20671745
D003907DexamethasoneValproic Acid inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23946490
C041517dibenzo(a,l)pyrene"[1,2,5,6-dibenzanthracene co-treated with dibenzo(a,l)pyrene] affects the expression of TSC22D3 mRNA"18711122
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of TSC22D3 mRNA21266533
D003999Dichloroacetic AcidDichloroacetic Acid results in decreased expression of TSC22D3 mRNA28962523
D002945CisplatinCisplatin affects the expression of TSC22D3 mRNA23300844
D002945CisplatinCisplatin results in increased expression of TSC22D3 mRNA27392435|2759478
D002945CisplatinCisplatin results in decreased expression of TSC22D3 mRNA22023808
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene results in increased activity of TSC22D3 protein27589886
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D004008DiclofenacDiclofenac results in increased expression of TSC22D3 mRNA26934552
C121718dicyclanildicyclanil results in increased expression of TSC22D3 mRNA15664270
D004041Dietary FatsDietary Fats results in decreased expression of TSC22D3 mRNA18042831
D002117CalcitriolCalcitriol results in decreased expression of TSC22D3 mRNA16002434|2648566
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of TSC22D3 mRNA27638505
D004121Dimethyl SulfoxideDimethyl Sulfoxide affects the expression of TSC22D3 mRNA24834073
D004147DioxinsDioxins affects the expression of TSC22D3 mRNA20463971
D004221DisulfiramDisulfiram results in decreased expression of TSC22D3 mRNA20530235
D004221DisulfiramDisulfiram results in increased expression of TSC22D3 mRNA20530235
D004237DiuronDiuron results in decreased expression of TSC22D3 mRNA25152437
D004317DoxorubicinTSC22D3 protein affects the reaction [Corticosterone results in decreased susceptibility to Doxorubicin]24480152
D004317DoxorubicinTSC22D3 protein inhibits the reaction [Doxorubicin affects the localization of CYCS protein]24480152
D004317DoxorubicinTSC22D3 protein inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]24480152
D004317DoxorubicinTSC22D3 protein results in decreased susceptibility to Doxorubicin24480152
D004365Drugs, Chinese Herbal"Drugs, Chinese Herbal results in increased expression of TSC22D3 mRNA"23811387
D004785Environmental PollutantsEnvironmental Pollutants results in increased expression of TSC22D3 mRNA25187966
D004918Erythromycin EstolateErythromycin Estolate results in decreased expression of TSC22D3 mRNA24412560
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of TSC22D3 mRNA25064622
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of TSC22D3 mRNA18936297
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of TSC22D3 mRNA23649840
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of TSC22D3 mRNA28329830
C007738fluoranthene"[1,2,5,6-dibenzanthracene co-treated with fluoranthene] affects the expression of TSC22D3 mRNA"18711122
D005485FlutamideFlutamide results in decreased expression of TSC22D3 mRNA24136188
D005557FormaldehydeFormaldehyde results in increased expression of TSC22D3 mRNA17938736|1884961
C069837fullerene C60fullerene C60 affects the expression of TSC22D3 mRNA19167457
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]23183181
C070081fulvestrantfulvestrant inhibits the reaction [Estradiol inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]23183181
C070081fulvestrantfulvestrant inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]25136773
C070081fulvestrantfulvestrant promotes the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181
D019833GenisteinESR1 mutant form inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]25136773
D019833Genisteinfulvestrant inhibits the reaction [Genistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]]25136773
D019833GenisteinGenistein inhibits the reaction [Dexamethasone promotes the reaction [NR3C1 protein binds to TSC22D3 promoter]]25136773
D019833GenisteinGenistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]25136773
D019833GenisteinGenistein inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]25136773
D019833GenisteinGenistein promotes the reaction [ESR1 protein binds to TSC22D3 promoter]25136773
C010176halofuginonehalofuginone results in decreased expression of TSC22D3 mRNA17180598
D017313FenretinideFenretinide results in decreased expression of TSC22D3 mRNA28973697
D006854HydrocortisoneHydrocortisone results in increased expression of TSC22D3 mRNA25763180
D006854HydrocortisoneMifepristone inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]25763180
D006854Hydrocortisone3-phenoxybenzoic acid inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006854Hydrocortisonecyhalothrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006854HydrocortisoneDDT inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006854HydrocortisoneDichlorodiphenyl Dichloroethylene inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006854HydrocortisoneHydrocortisone results in increased expression of TSC22D3 mRNA26647222
D006854HydrocortisoneMethoxychlor inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006854HydrocortisoneMifepristone inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006854Hydrocortisone"N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]"26647222
D006854Hydrocortisone"o,p'-DDT inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]"26647222
D006854Hydrocortisoneresmethrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of TSC22D3 mRNA18951874
C041508indeno(1,2,3-cd)pyrene"indeno(1,2,3-cd)pyrene results in decreased expression of TSC22D3 mRNA"26377693
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TSC22D3 mRNA25613284
D007545IsoproterenolIsoproterenol results in increased expression of TSC22D3 mRNA20003209
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TSC22D3 mRNA23086925
C067713lactacystinlactacystin inhibits the reaction [[benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone results in decreased activity of CASP8 protein] inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 protein]]20671745
C008261lead acetatelead acetate affects the expression of TSC22D3 mRNA21829687
C008261lead acetatelead acetate results in increased expression of TSC22D3 mRNA22641619
D064704LevofloxacinLevofloxacin results in increased expression of TSC22D3 mRNA24136188
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of TSC22D3 mRNA"25673294
C083152liquiritigeninliquiritigenin inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23183181
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TSC22D3 mRNA21641980
D017258Medroxyprogesterone AcetateMedroxyprogesterone Acetate results in increased expression of TSC22D3 mRNA20843944
D008627Mercuric ChlorideMercuric Chloride results in increased expression of TSC22D3 mRNA16507785
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in increased expression of TSC22D3 mRNA19564919
D008694MethamphetamineMethamphetamine results in increased expression of TSC22D3 mRNA19564919
D008731MethoxychlorMethoxychlor inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of TSC22D3 mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of TSC22D3 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of TSC22D3 mRNA"20188158
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of TSC22D3 mRNA24810058
D008777MethyltestosteroneMethyltestosterone results in increased expression of TSC22D3 mRNA29191790
D008797MetyraponeMetyrapone inhibits the reaction [Ozone results in increased expression of TSC22D3 mRNA]27037194
D015735MifepristoneMifepristone inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]25763180
D015735MifepristoneMifepristone inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
C452423N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amineN-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in increased expression of TSC22D3 mRNA16052530
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of TSC22D3 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of TSC22D3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of TSC22D3 mRNA"25620056
D009285NaphthoquinonesNaphthoquinones results in increased expression of TSC22D3 mRNA23811387
C017096n-butoxyethanoln-butoxyethanol results in increased expression of TSC22D3 mRNA19812364
C070021N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide"N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]"26647222
D019829NevirapineNevirapine results in increased expression of TSC22D3 mRNA23947594
C119536nickel acetateNFE2L2 protein inhibits the reaction [nickel acetate results in increased expression of TSC22D3 mRNA]23023193
C119536nickel acetatenickel acetate results in decreased expression of TSC22D3 mRNA23023193
C028007nickel monoxidenickel monoxide results in increased expression of TSC22D3 mRNA19167457
C029938nickel sulfatenickel sulfate results in decreased expression of TSC22D3 mRNA25673294
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in decreased expression of TSC22D3 mRNA17616710
C570896NSC305787NSC305787 results in increased expression of TSC22D3 mRNA27137931
C570897NSC668394NSC668394 results in increased expression of TSC22D3 mRNA27137931
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of TSC22D3 mRNA20971185
C016340o,p'-DDT"o,p'-DDT inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]"26647222
D009966OrphenadrineOrphenadrine affects the expression of TSC22D3 mRNA23665939
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of TSC22D3 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of TSC22D3 mRNA25729387
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of TSC22D3 mRNA17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of TSC22D3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of TSC22D3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of TSC22D3 mRNA]17655762
C472349oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholineVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of TSC22D3 mRNA]17655762
D010098OxycodoneOxycodone results in increased expression of TSC22D3 mRNA23439660
D010126OzoneMetyrapone inhibits the reaction [Ozone results in increased expression of TSC22D3 mRNA]27037194
D010126OzoneOzone results in increased expression of TSC22D3 mRNA23805001|2703719
D017239PaclitaxelPaclitaxel analog results in increased expression of TSC22D3 mRNA15585946
D000073878Palm OilPalm Oil results in decreased expression of TSC22D3 mRNA18042831
D010269ParaquatParaquat affects the expression of TSC22D3 mRNA25064622
D010269Paraquat"[17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of TSC22D3 mRNA"17275934
D052638Particulate Matteroxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Particulate Matter affects the expression of TSC22D3 mRNA]17655762
D052638Particulate MatterParticulate Matter affects the expression of TSC22D3 mRNA17655762
D052638Particulate MatterParticulate Matter promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of TSC22D3 mRNA]17655762
D052638Particulate MatterParticulate Matter results in increased expression of TSC22D3 mRNA23805001
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of TSC22D3 mRNA18593933
D010578PetroleumPetroleum affects the expression of TSC22D3 mRNA25208076
D010634PhenobarbitalPhenobarbital affects the expression of TSC22D3 mRNA23091169
D010634PhenobarbitalPhenobarbital results in increased expression of TSC22D3 mRNA19270015
C006253pirinixic acidpirinixic acid results in increased expression of TSC22D3 mRNA17426115|1844570
C013649plastochromanol 8plastochromanol 8 results in increased expression of TSC22D3 protein23941772
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of TSC22D3 mRNA22714537
D011374Progesterone[Estradiol co-treated with Progesterone] results in increased expression of TSC22D3 mRNA20660070
D011374Progesterone[Progesterone co-treated with Estradiol] results in increased expression of TSC22D3 mRNA17404688
D011374ProgesteroneProgesterone results in increased expression of TSC22D3 mRNA17404688|2086464
D011374ProgesteroneProgesterone results in increased expression of TSC22D3 mRNA20726854
D011372ProgestinsProgestins results in decreased expression of TSC22D3 mRNA19609016
D011441PropylthiouracilPropylthiouracil results in decreased expression of TSC22D3 mRNA24780913
C043680ptaquilosideptaquiloside results in increased expression of TSC22D3 mRNA23274088
D011794QuercetinQuercetin results in decreased expression of TSC22D3 mRNA18095365
C100036resmethrinresmethrin inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA]26647222
C059514resveratrol[Coumestrol co-treated with resveratrol] results in decreased expression of TSC22D3 mRNA19167446
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in increased expression of TSC22D3 mRNA19564919
D012715Sesame OilSesame Oil results in decreased expression of TSC22D3 mRNA29191790
D012822Silicon DioxideSilicon Dioxide results in decreased expression of TSC22D3 mRNA25351596
D012822Silicon DioxideSilicon Dioxide results in decreased expression of TSC22D3 mRNA23221170
D012822Silicon DioxideSilicon Dioxide results in increased expression of TSC22D3 mRNA19073995
C009277sodium arsenatesodium arsenate results in decreased expression of TSC22D3 mRNA23922661
C009277sodium arsenatesodium arsenate results in decreased expression of TSC22D3 mRNA21795629
C009277sodium arsenatesodium arsenate results in increased expression of TSC22D3 mRNA21795629
D053260SootSoot results in increased expression of TSC22D3 mRNA26551751
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in decreased expression of TSC22D3 mRNA21641980
D013629TamoxifenTamoxifen affects the expression of TSC22D3 mRNA20937368
D013739TestosteroneTSC22D3 gene mutant form results in increased abundance of Testosterone22556341
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TSC22D3 mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TSC22D3 mRNA19770486|2597527
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of TSC22D3 mRNA19933214|2405805
D013749Tetrachlorodibenzodioxin"[17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol co-treated with Paraquat co-treated with Tetrachlorodibenzodioxin] results in increased expression of TSC22D3 mRNA"17275934
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of TSC22D3 mRNA21215274|2172422
D013752TetracyclineTetracycline affects the expression of TSC22D3 mRNA25064622
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TSC22D3 mRNA25613284
D013853ThioacetamideThioacetamide affects the expression of TSC22D3 mRNA25064622
D013893ThiramThiram results in decreased expression of TSC22D3 mRNA20530235
C009495titanium dioxidetitanium dioxide results in increased expression of TSC22D3 mRNA23131501|2340900
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TSC22D3 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of TSC22D3 mRNA20133372
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of TSC22D3 mRNA25729387
D014212TretinoinTretinoin results in increased expression of TSC22D3 mRNA20530235
D014212Tretinoin[Tretinoin co-treated with arsenic trioxide] results in decreased expression of TSC22D3 mRNA15894607
D014212TretinoinTretinoin results in increased expression of TSC22D3 mRNA16054129|2193413
C011559tributyltintributyltin results in decreased expression of TSC22D3 mRNA28011154
D014520UrethaneUrethane results in increased expression of TSC22D3 mRNA28818685
C406224valdecoxibvaldecoxib results in decreased expression of TSC22D3 mRNA24136188
D014635Valproic AcidValproic Acid affects the expression of TSC22D3 mRNA25064622
D014635Valproic AcidValproic Acid affects the expression of TSC22D3 mRNA25979313
D014635Valproic AcidValproic Acid inhibits the reaction [Dexamethasone results in increased expression of TSC22D3 mRNA]23946490
D014635Valproic AcidValproic Acid results in decreased expression of TSC22D3 mRNA23665938
D001335Vehicle Emissionsoxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine promotes the reaction [Vehicle Emissions affects the expression of TSC22D3 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions affects the expression of TSC22D3 mRNA17655762
D001335Vehicle EmissionsVehicle Emissions promotes the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine affects the expression of TSC22D3 mRNA]17655762
D001335Vehicle EmissionsVehicle Emissions results in increased expression of TSC22D3 mRNA18849615
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of TSC22D3 gene25560391
C025643vinclozolinvinclozolin affects the expression of TSC22D3 mRNA23034163
D014874Water Pollutants, Chemical"Water Pollutants, Chemical affects the expression of TSC22D3 mRNA"25208076
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of TSC22D3 mRNA18593933
C088658zoledronic acidzoledronic acid results in increased expression of TSC22D3 mRNA20977926

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0003700DNA-binding transcription factor activity-TAS8982256  
GO:0043426MRF binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000122negative regulation of transcription by RNA polymerase II-IEA-  
GO:0006355regulation of transcription, DNA-templated-TAS8982256  
GO:0006970response to osmotic stress-IEA-  
GO:0034220ion transmembrane transport-TAS-  
GO:0048642negative regulation of skeletal muscle tissue development-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005829cytosol-TAS-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-2672351Stimuli-sensing channelsTAS
R-HSA-382551Transport of small moleculesTAS
R-HSA-983712Ion channel transportTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26913089X chromosome-wide analysis identifies DNA methylation sites influenced by cigarette smoking. (2016)Klebaner DClin Epigenetics