Gene: EEF1A1

1915
CCS-3|CCS3|EE1A1|EEF-1|EEF1A|EF-Tu|EF1A|GRAF-1EF|HNGC:16303|LENG7|PTI1|eEF1A-1
eukaryotic translation elongation factor 1 alpha 1
protein-coding
6q13
Ensembl:ENSG00000156508 MIM:130590 Vega:OTTHUMG00000015031 UniprotKB:P68104
NC_000006.12
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.130e-1 (AD)  9.489e-2 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
EEF1G0.963
RPL100.957
RPL40.954
RPL50.953
RPL70.951
RPS4X0.949
RHOA0.947
RPS130.946
RPL170.945
TPT10.943

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.835
OR4F5-0.789
ADRA1D-0.175
OPRD1-0.168
SCRT2-0.16
ABCC12-0.157
FBLN7-0.153
RHO-0.152
CYP1A1-0.148
CALHM1-0.145

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB01593ZincSmall Molecule7440-66-6Approved|InvestigationalTarget
DB04315Guanosine-5'-DiphosphateSmall Molecule146-91-8ExperimentalTarget
DB09130CopperSmall Molecule7440-50-8Approved|InvestigationalTarget
DB11638ArtenimolSmall Molecule71939-50-9Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in increased expression of EEF1A1 mRNA"19162173
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of EEF1A1 protein"21673325
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EEF1A1 mRNA"19167446
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of EEF1A1 mRNA"27015953
C0235142,6-dinitrotoluene"2,6-dinitrotoluene results in decreased expression of EEF1A1 mRNA"19417177
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of EEF1A1 mRNA"12376462
C0303702-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone"2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone results in increased expression of EEF1A1 mRNA"20206263
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EEF1A1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EEF1A1 mRNA"27188386
C4565477-((9-fluorenylmethoxycarbonyl)cyclohexylalanyllysyl)amino-4-methylcoumarin7-((9-fluorenylmethoxycarbonyl)cyclohexylalanyllysyl)amino-4-methylcoumarin results in decreased expression of EEF1A1 mRNA27015953
C089740abirateroneabiraterone results in decreased expression of EEF1A1 mRNA27015953
D000082AcetaminophenAcetaminophen affects the expression of EEF1A1 mRNA17562736
D019342Acetic AcidAcetic Acid affects the expression of EEF1A1 protein21296659
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of EEF1A1 mRNA27153756
C006632arsenic trioxidearsenic trioxide results in decreased expression of EEF1A1 protein15894607|2525818
C006632arsenic trioxide[Tretinoin co-treated with arsenic trioxide] results in decreased expression of EEF1A1 protein15894607
D001241AspirinAspirin results in increased expression of EEF1A1 mRNA14976132
D001374AzacitidineAzacitidine results in decreased expression of EEF1A1 mRNA20823114
C487081belinostatbelinostat affects the expression of EEF1A1 mRNA27015953
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of EEF1A1 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [AHR protein binds to EEF1A1 promoter]19654925
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of EEF1A1 mRNA22228805
D004958Estradiol[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EEF1A1 mRNA20823114
C110172BHTOH-QMBHTOH-QM binds to EEF1A1 protein16533022
C006780bisphenol Abisphenol A results in increased expression of EEF1A1 mRNA15223131
C006780bisphenol Abisphenol A results in increased expression of EEF1A1 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EEF1A1 mRNA28628672
C423844BL 11282BL 11282 binds to EEF1A1 protein18420036
C099813bromochloroacetic acidbromochloroacetic acid results in increased expression of EEF1A1 protein21296659
C515564bromovaninbromovanin results in decreased expression of EEF1A1 protein21419150
D019328Buthionine SulfoximineButhionine Sulfoximine results in increased expression of EEF1A1 mRNA15878706
C026105butylidenephthalidebutylidenephthalide results in decreased expression of EEF1A1 protein23770345
D002101Cacodylic AcidCacodylic Acid results in decreased expression of EEF1A1 mRNA17720352
D002104CadmiumCadmium results in increased expression of EEF1A1 mRNA17327700
C028031cadmium acetatecadmium acetate results in increased expression of EEF1A1 mRNA12965115
D019256Cadmium ChlorideCadmium Chloride affects the expression of EEF1A1 protein24874008
D019256Cadmium ChlorideCadmium Chloride results in increased expression of EEF1A1 mRNA17327700
D002110Caffeine"[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EEF1A1 mRNA"20230807
D002110Caffeine"Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of EEF1A1 mRNA]"20230807
D002220CarbamazepineCarbamazepine affects the expression of EEF1A1 mRNA25979313
D002235Carbofuran[Lindane co-treated with metolachlor co-treated with Carbofuran] results in decreased expression of EEF1A1 mRNA21075942
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of EEF1A1 mRNA23650126
D002734Chlorophyll"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of EEF1A1 mRNA]"22079312
C100187chloropicrinchloropicrin results in decreased expression of EEF1A1 mRNA26352163
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EEF1A1 gene20938992
D002994ClofibrateClofibrate results in decreased expression of EEF1A1 mRNA22300585
C018021cobaltous chloridecobaltous chloride results in increased expression of EEF1A1 mRNA17553155
D003042CocaineCocaine affects the expression of EEF1A1 mRNA20187946
D003300CopperEEF1A1 protein binds to Copper14534351
D003300CopperMT1 affects the reaction [Copper results in increased expression of EEF1A1 mRNA]16629173
D003300CopperMT2 affects the reaction [Copper results in increased expression of EEF1A1 mRNA]16629173
D019327Copper SulfateCopper Sulfate results in decreased expression of EEF1A1 mRNA19549813
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of EEF1A1 mRNA"19167446
C009160cyclonitecyclonite affects the expression of EEF1A1 mRNA19417177
D016572CyclosporineCyclosporine results in decreased expression of EEF1A1 mRNA21163907|2556210
D013759DronabinolDronabinol affects the expression of EEF1A1 mRNA11015613
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EEF1A1 mRNA28628672
C041517dibenzo(a,l)pyrene"Chlorophyll inhibits the reaction [dibenzo(a,l)pyrene results in increased expression of EEF1A1 mRNA]"22079312
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased expression of EEF1A1 mRNA"22079312
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of EEF1A1 mRNA21266533
D003994Bucladesine[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EEF1A1 mRNA20823114
C000944dicrotophosdicrotophos results in decreased expression of EEF1A1 mRNA28302478
D004041Dietary FatsDietary Fats results in increased expression of EEF1A1 mRNA25016146
D004041Dietary FatsDietary Fats results in increased expression of EEF1A1 mRNA21852083
D004041Dietary Fatsresveratrol inhibits the reaction [Dietary Fats results in increased expression of EEF1A1 mRNA]21852083
C039060dihydroartemisinindihydroartemisinin analog binds to EEF1A1 protein modified form26340163
D002117CalcitriolCalcitriol results in increased expression of EEF1A1 mRNA12875902
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of EEF1A1 protein"20045496
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in increased expression of EEF1A1 mRNA"12376462
D004237DiuronDiuron results in decreased expression of EEF1A1 mRNA21551480
D004298DopamineDopamine results in increased expression of EEF1A1 protein24675778
C479799(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of EEF1A1 mRNA15528975
C118739entinostatentinostat results in increased expression of EEF1A1 mRNA27015953
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of EEF1A1 mRNA22079256
D000431EthanolEthanol results in increased expression of EEF1A1 mRNA15353170
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of EEF1A1 mRNA17108234
C074031exenatideexenatide results in increased expression of EEF1A1 mRNA27015953
C504383fenbuconazolefenbuconazole results in increased expression of EEF1A1 mRNA15942997
C000499ferric oxideferric oxide analog results in decreased expression of EEF1A1 mRNA25086211
D005419FlavonoidsFlavonoids results in decreased expression of EEF1A1 mRNA18035473
D005472FluorouracilFluorouracil results in increased expression of EEF1A1 mRNA17982676
D005472FluorouracilTP53 protein inhibits the reaction [Fluorouracil results in increased expression of EEF1A1 mRNA]17982676
D005472FluorouracilFluorouracil affects the expression of EEF1A1 protein21296659
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EEF1A1 gene20938992
D019833GenisteinGenistein results in increased methylation of EEF1A1 gene28505145
D005839GentamicinsGentamicins results in decreased expression of EEF1A1 mRNA22061828
D005839GentamicinsGentamicins results in increased expression of EEF1A1 mRNA22061828
D005947GlucoseEEF1A1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]21124846
C010974glyphosateglyphosate results in increased expression of EEF1A1 protein20045496
D006108GraphiteGraphite results in increased expression of EEF1A1 protein22157353
D000068877Imatinib MesylateImatinib Mesylate results in decreased expression of EEF1A1 mRNA27015953
C020758indium trichlorideindium trichloride results in decreased expression of EEF1A1 protein19539025
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EEF1A1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of EEF1A1 mRNA28628672
D007854LeadLead affects the expression of EEF1A1 mRNA28903495
D001556Lindane[Lindane co-treated with metolachlor co-treated with Carbofuran] results in decreased expression of EEF1A1 mRNA21075942
D001556LindaneLindane affects the expression of EEF1A1 mRNA22001173
D008094LithiumLithium results in increased expression of EEF1A1 protein18296634
D008344Maneb[Paraquat co-treated with Maneb] results in increased expression of EEF1A1 mRNA18386188
D017258Medroxyprogesterone Acetate[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of EEF1A1 mRNA20823114
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EEF1A1 gene20938992
D008727MethotrexateEEF1A1 mRNA results in decreased susceptibility to Methotrexate19732436
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of EEF1A1 mRNA28001369
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of EEF1A1 protein26965727
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of EEF1A1 mRNA"26251327
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of EEF1A1 protein24675778
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of EEF1A1 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of EEF1A1 mRNA"20230807
D0156321-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine"Caffeine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of EEF1A1 mRNA]"20230807
C051786metolachlor[Lindane co-treated with metolachlor co-treated with Carbofuran] results in decreased expression of EEF1A1 mRNA21075942
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of EEF1A1 protein"22157353
D009569Nitric OxideNitric Oxide deficiency results in increased expression of EEF1A1 mRNA15878706
C002741N-nitrosomorpholineN-nitrosomorpholine results in increased expression of EEF1A1 protein19716841
C025589ochratoxin Aochratoxin A results in decreased expression of EEF1A1 mRNA16251485
D010100OxygenEEF1A1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]21124846
D010269Paraquat[Paraquat co-treated with Maneb] results in increased expression of EEF1A1 mRNA18386188
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in decreased expression of EEF1A1 protein19954255
D010936Plant ExtractsPlant Extracts results in increased expression of EEF1A1 mRNA23557933
D028321Plant PreparationsPlant Preparations affects the expression of EEF1A1 mRNA16046712
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of EEF1A1 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of EEF1A1 mRNA22079256
D011374ProgesteroneProgesterone results in decreased expression of EEF1A1 mRNA23018184
D011441PropylthiouracilPropylthiouracil results in decreased expression of EEF1A1 mRNA18077114
D011441PropylthiouracilPropylthiouracil results in increased expression of EEF1A1 mRNA24780913
C100573prostaglandin A1prostaglandin A1 analog results in increased metabolism of EEF1A1 protein19800325
C059514resveratrolresveratrol results in increased expression of EEF1A1 protein25505154
C059514resveratrolresveratrol inhibits the reaction [Dietary Fats results in increased expression of EEF1A1 mRNA]21852083
D012176RetinoidsRetinoids results in decreased expression of EEF1A1 protein28886987
D012822Silicon DioxideSilicon Dioxide analog affects the secretion of EEF1A1 protein25895662
C009277sodium arsenatesodium arsenate results in increased expression of EEF1A1 mRNA12727804
C017947sodium arsenitesodium arsenite results in increased expression of EEF1A1 mRNA12727804
D012969Sodium FluorideSodium Fluoride results in decreased expression of EEF1A1 protein28918527
D012969Sodium FluorideSodium Fluoride results in increased expression of EEF1A1 protein27548804
C086235swinholide Aswinholide A affects the reaction [EEF1A1 protein binds to SPP1 5' UTR]19026636
D014284TriiodothyronineTriiodothyronine results in increased expression of EEF1A1 mRNA17403546
C061133tamibarotenetamibarotene results in increased expression of EEF1A1 mRNA15498508
D013629TamoxifenTamoxifen results in increased expression of EEF1A1 protein17098229
D013629Tamoxifen[Tretinoin co-treated with Tamoxifen] results in increased expression of EEF1A1 protein17098229
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of EEF1A1 mRNA22574217
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of EEF1A1 mRNA21570461
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of EEF1A1 mRNA28973375
D013755Tetradecanoylphorbol AcetateTetradecanoylphorbol Acetate results in increased expression of EEF1A1 protein20045496
C014215tetrahydropalmatinetetrahydropalmatine results in increased expression of EEF1A1 protein20109541
C009495titanium dioxidetitanium dioxide results in increased expression of EEF1A1 mRNA23557971
D014212Tretinoin[Tretinoin co-treated with arsenic trioxide] results in decreased expression of EEF1A1 protein15894607
D014212Tretinoin[Tretinoin co-treated with Tamoxifen] results in increased expression of EEF1A1 protein17098229
D014212TretinoinTretinoin results in decreased expression of EEF1A1 mRNA21934132
D014212TretinoinTretinoin results in increased expression of EEF1A1 mRNA12875902|1549850
D014212TretinoinTretinoin results in increased expression of EEF1A1 protein17098229
C032910triadimefontriadimefon results in decreased expression of EEF1A1 mRNA27015953
D014241TrichloroethyleneTrichloroethylene results in increased expression of and affects the localization of EEF1A1 protein22771849
D014241TrichloroethyleneTrichloroethylene results in increased methylation of EEF1A1 gene27618143
C012589trichostatin Atrichostatin A results in decreased expression of EEF1A1 mRNA28542535
C040533trimethyltin chloridetrimethyltin chloride results in decreased expression of EEF1A1 mRNA27015953
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in decreased expression of EEF1A1 mRNA12163651
D014501UraniumUranium affects the expression of EEF1A1 mRNA15672453
D017974Uranium CompoundsUranium Compounds results in decreased expression of EEF1A1 mRNA19654044
C005460uranyl acetateuranyl acetate affects the expression of EEF1A1 mRNA15672453
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EEF1A1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of EEF1A1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of EEF1A1 mRNA23179753|2438349
D014635Valproic AcidValproic Acid affects the expression of EEF1A1 mRNA27015953
D014801Vitamin AVitamin A deficiency results in decreased expression of EEF1A1 mRNA12163651
C111237vorinostatvorinostat results in increased expression of EEF1A1 mRNA18769122
D015032ZincEEF1A1 protein binds to Zinc14534351
C016837zinc chloridezinc chloride results in decreased expression of EEF1A1 mRNA19683351
D019287Zinc SulfateZinc Sulfate affects the expression of EEF1A1 protein25162517

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000049tRNA binding-IDA12426392  
GO:0003723RNA binding-HDA22658674  22681889  
GO:0003746translation elongation factor activity-IBA21873635  
GO:0003746translation elongation factor activity-TAS17595531  
GO:0003924GTPase activity-IBA21873635  
GO:0005515protein binding-IPI9852145  15161933  16712842  16828757  17373842  17980171  
18000879  19158340  20618440  20838377  23260144  24209753  
24705354  26497934  
GO:0005516calmodulin binding-IEA-  
GO:0005525GTP binding-TAS3512269  
GO:0019901protein kinase binding-IPI17177976  17595531  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006355regulation of transcription, DNA-templated-IEA-  
GO:0006412translation-IBA21873635  
GO:0006414translational elongation-IBA21873635  
GO:0006414translational elongation-TAS8812466  
GO:0043312neutrophil degranulation-TAS-  
GO:0071364cellular response to epidermal growth factor stimulus-IDA9852145  
GO:1904714regulation of chaperone-mediated autophagy-NAS20797626  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-HDA23580065  
GO:0005634nucleus-HDA21630459  
GO:0005634nucleus-IDA8743958  9852145  17177976  
GO:0005730nucleolus-IDA9852145  
GO:0005737cytoplasm-IDA8743958  9852145  17177976  17980171  24209753  
GO:0005737cytoplasm-ISS-  
GO:0005737cytoplasm-TAS3512269  
GO:0005829cytosol-IDA19158340  
GO:0005829cytosol-TAS-  
GO:0005853eukaryotic translation elongation factor 1 complex-TAS2564392  
GO:0005886plasma membrane-IDA26497934  
GO:0016020membrane-HDA19946888  
GO:0030864cortical actin cytoskeleton-IDA19158340  
GO:0032587ruffle membrane-IDA19158340  
GO:0034774secretory granule lumen-TAS-  
GO:0043209myelin sheath-IEA-  
GO:0070062extracellular exosome-HDA12519789  19056867  19199708  20458337  
GO:0098574cytoplasmic side of lysosomal membrane-NAS20797626  
GO:1904813ficolin-1-rich granule lumen-TAS-  
KEGG ID KEGG Term
hsa03013RNA transport
Reactome ID Reactome Term Evidence
R-HSA-156842Eukaryotic Translation ElongationTAS
R-HSA-156842Eukaryotic Translation ElongationIEA
R-HSA-156902Peptide chain elongationIEA
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-2262752Cellular responses to stressTAS
R-HSA-3371511HSF1 activationTAS
R-HSA-3371556Cellular response to heat stressTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392499Metabolism of proteinsIEA
R-HSA-597592Post-translational protein modificationTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-72766TranslationTAS
R-HSA-72766TranslationIEA
R-HSA-8876725Protein methylationTAS
R-HSA-8953897Cellular responses to external stimuliTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26518718Identification of gene markers in the development of smoking-induced lung cancer. (2016 Jan 15)Yang ZGene