Gene: CRYBG1

202
AIM1|ST4
crystallin beta-gamma domain containing 1
protein-coding
6q21
Ensembl:ENSG00000112297 MIM:601797 Vega:OTTHUMG00000015302 UniprotKB:Q9Y4K1
NC_000006.12
SNP Mapped
CD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.780e-1 (AD)  8.649e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5486512-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of CRYBG1 mRNA19933214
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of CRYBG1 mRNA21420995
D000082AcetaminophenAcetaminophen affects the expression of CRYBG1 mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of CRYBG1 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of CRYBG1 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of CRYBG1 gene27153756
C430898AGN 194204AGN 194204 results in decreased expression of CRYBG1 mRNA16339527
D000447AldehydesAldehydes results in increased expression of CRYBG1 mRNA25014914
C487081belinostatbelinostat results in increased expression of CRYBG1 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
D001554BenzeneBenzene results in increased expression of CRYBG1 mRNA19162166
D001564Benzo(a)pyreneAHR protein affects the reaction [Benzo(a)pyrene affects the expression of CRYBG1 mRNA]22228805
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CRYBG1 mRNA21569818|2261060
D004958EstradiolEstradiol results in decreased expression of CRYBG1 mRNA21185374
C006780bisphenol Abisphenol A results in decreased expression of CRYBG1 mRNA25181051
C018475butyraldehydebutyraldehyde results in increased expression of CRYBG1 mRNA26079696
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CRYBG1 mRNA26472689
D002857ChromiumChromium results in decreased expression of CRYBG1 mRNA21437242
D019327Copper SulfateCopper Sulfate results in decreased expression of CRYBG1 mRNA19549813
C030973cupric oxidecupric oxide results in increased expression of CRYBG1 protein25470785
D016572CyclosporineCyclosporine results in decreased expression of CRYBG1 mRNA25562108
D016572CyclosporineCyclosporine results in increased expression of CRYBG1 mRNA27989131
D003907DexamethasoneDexamethasone results in increased expression of CRYBG1 mRNA12782123
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of CRYBG1 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of CRYBG1 mRNA27392435
C118739entinostatentinostat results in increased expression of CRYBG1 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
D004397FonofosFonofos results in increased methylation of CRYBG1 promoter22847954
D017313FenretinideFenretinide results in decreased expression of CRYBG1 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CRYBG1 mRNA20044591
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CRYBG1 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of CRYBG1 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of CRYBG1 mRNA24796395
D037742Nanotubes, Carbon"Nanotubes, Carbon affects the expression of CRYBG1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of CRYBG1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CRYBG1 mRNA"25620056
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of CRYBG1 mRNA26272509
D010278ParathionParathion results in increased methylation of CRYBG1 promoter22847954
C046012pentanalpentanal results in increased expression of CRYBG1 mRNA26079696
C006253pirinixic acidpirinixic acid results in increased expression of CRYBG1 mRNA18445702|2381119
D010936Plant ExtractsPlant Extracts results in increased expression of CRYBG1 mRNA23557933
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CRYBG1 mRNA22714537
C005556propionaldehydepropionaldehyde results in increased expression of CRYBG1 mRNA26079696
D011794QuercetinQuercetin results in decreased expression of CRYBG1 mRNA21632981
C012568terbufosterbufos results in increased methylation of CRYBG1 promoter22847954
C020806tetrabromobisphenol Atetrabromobisphenol A results in decreased expression of CRYBG1 mRNA25172293
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CRYBG1 mRNA20106945|2163298
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CRYBG1 mRNA18691609|1977048
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CRYBG1 mRNA25613284
C009495titanium dioxidetitanium dioxide results in increased expression of CRYBG1 mRNA23557971
D019772TopotecanCRYBG1 protein affects the susceptibility to Topotecan16217747
D014212TretinoinTretinoin results in increased expression of CRYBG1 mRNA21934132
C012589trichostatin Atrichostatin A results in increased expression of CRYBG1 mRNA24935251
C057693troglitazonetroglitazone results in decreased expression of CRYBG1 mRNA28973697
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRYBG1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CRYBG1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CRYBG1 mRNA19101580|2317975

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003674molecular_function-ND-  
GO:0030246carbohydrate binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0008150biological_process-ND-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005575cellular_component-ND-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal