Gene: ENO3

2027
GSD13|MSE
enolase 3
protein-coding
17p13.2
Ensembl:ENSG00000108515 MIM:131370 Vega:OTTHUMG00000099394 UniprotKB:P13929
NG_012063.2
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.949e-1 (AD)  7.940e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg12331425chr17:4854391ENO31.100e-8Smoking28686328

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CA30.576
EIF4EBP30.544
RPL3L0.543
ATP2A10.534
CKM0.532
KLHL400.52
TNNI10.517
MYL10.516
MYLPF0.509
MB0.509

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.363
OR4F29-0.32
GLP2R-0.287
HTR4-0.286
LECT2-0.26
MTNR1B-0.25
ASB18-0.245
GPR52-0.244
WNT2-0.232
C6orf141-0.225

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB017092-phospho-D-glyceric acidSmall MoleculeExperimentalTarget
DB01819PhosphoenolpyruvateSmall Molecule138-08-9ExperimentalTarget
DB027262-Phosphoglycolic AcidSmall Molecule13147-57-4ExperimentalTarget
DB03645Phosphonoacetohydroxamic AcidSmall MoleculeExperimentalTarget
ID Drug Name Action PubMed
C0636091,2-dimethyl-4-nitrobenzene"1,2-dimethyl-4-nitrobenzene results in increased expression of ENO3 mRNA"19784758
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of ENO3 mRNA"19162173
C4838392,2',3,4,4',5',6-heptabromodiphenyl ether"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in decreased expression of ENO3 protein"18258299
C4838392,2',3,4,4',5',6-heptabromodiphenyl ether"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in increased expression of ENO3 protein"18258299
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of ENO3 mRNA"28973690
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of ENO3 mRNA"23196670
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of ENO3 mRNA25064622
D000082AcetaminophenAcetaminophen affects the expression of ENO3 mRNA19784758
D000082AcetaminophenAcetaminophen results in decreased expression of ENO3 mRNA19784758
D000082AcetaminophenAcetaminophen results in increased expression of ENO3 mRNA19784758
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of ENO3 mRNA27153756
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of ENO3 mRNA23630614
C430898AGN 194204AGN 194204 results in increased expression of ENO3 mRNA16339527
D000638AmiodaroneAmiodarone affects the expression of ENO3 mRNA25064622
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ENO3 mRNA16483693
D001151ArsenicArsenic results in decreased expression of ENO3 protein22552367
D001280AtrazineAtrazine results in increased expression of ENO3 mRNA22378314
D001507BeclomethasoneBeclomethasone results in increased expression of ENO3 mRNA23656298
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of ENO3 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ENO3 mRNA21632981|2623829
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ENO3 mRNA21715664|2222880
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA25566086
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydeMYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of ENO3 mRNA]25566086
D004958EstradiolEstradiol results in decreased expression of ENO3 mRNA15757668
D004958EstradiolEstradiol results in decreased expression of ENO3 mRNA19484750
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ENO3 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of ENO3 mRNA25181051
C018475butyraldehydebutyraldehyde results in increased expression of ENO3 mRNA26079696
C584509C646 compoundC646 compound results in increased expression of ENO3 mRNA26191083
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ENO3 protein26220685
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ENO3 protein26220685
D002220CarbamazepineCarbamazepine affects the expression of ENO3 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ENO3 mRNA17484886
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of ENO3 mRNA26272509
D002746ChlorpromazineChlorpromazine affects the expression of ENO3 mRNA25064622
D002857ChromiumLEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of ENO3 mRNA]16940432
C074702chromium hexavalent ionchromium hexavalent ion results in decreased expression of ENO3 protein22552367
C018021cobaltous chloridecobaltous chloride results in increased expression of ENO3 protein24386269
D003300CopperCopper deficiency results in decreased expression of ENO3 protein18993053
D019327Copper SulfateCopper Sulfate results in decreased expression of ENO3 mRNA19549813
D016572CyclosporineCyclosporine affects the expression of ENO3 mRNA25064622
D016572CyclosporineCyclosporine results in decreased expression of ENO3 mRNA21632981|2556210
D003561CytarabineCytarabine results in decreased expression of ENO3 mRNA21198554
C004742daidzeindaidzein results in decreased expression of ENO3 mRNA15757668
C014347decitabinedecitabine affects the expression of ENO3 mRNA23300844
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ENO3 mRNA28628672
D003976DiazinonDiazinon results in increased methylation of ENO3 gene22964155
D002945CisplatinCisplatin affects the expression of ENO3 mRNA23300844
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of ENO3 mRNA27392435
C042080diisodecyl phthalatediisodecyl phthalate results in increased expression of ENO3 mRNA25270620
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of ENO3 mRNA28939011
D004222DisulfotonDisulfoton results in decreased expression of ENO3 mRNA12935443
D004317Doxorubicin[Doxorubicin co-treated with MT2A protein] results in decreased expression of ENO3 protein16144979
D004317DoxorubicinDoxorubicin results in decreased expression of ENO3 mRNA19915844
C118739entinostatentinostat results in increased expression of ENO3 mRNA27188386
D000431EthanolEthanol results in increased expression of ENO3 protein23200777
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of ENO3 mRNA25064622
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of ENO3 protein20227414
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ENO3 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ENO3 mRNA17942748
D005411Flame RetardantsFlame Retardants results in decreased expression of ENO3 protein18258299
D005411Flame RetardantsFlame Retardants results in increased expression of ENO3 protein18258299
D019833GenisteinGenistein results in decreased expression of ENO3 mRNA15757668
D006108GraphiteGraphite results in increased expression of ENO3 mRNA27440207
C017363hexabromobenzene"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in decreased expression of ENO3 protein"18258299
C017363hexabromobenzene"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in increased expression of ENO3 protein"18258299
C089796hexabromocyclododecane"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in decreased expression of ENO3 protein"18258299
C089796hexabromocyclododecane"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in increased expression of ENO3 protein"18258299
C001654hyperforinhyperforin affects the expression of ENO3 protein15095150
C492448ICG 001ICG 001 results in increased expression of ENO3 mRNA26191083
C016517indole-3-carbinolindole-3-carbinol affects the expression of ENO3 mRNA21396975
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ENO3 mRNA28628672
D007213IndomethacinIndomethacin results in increased expression of ENO3 mRNA28201806
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ENO3 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ENO3 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of ENO3 mRNA27392435
C410337K 7174K 7174 results in decreased expression of ENO3 mRNA24086573
C029310lardlard results in increased expression of ENO3 mRNA26115784
C008261lead acetatelead acetate results in increased expression of ENO3 mRNA21829687
D008727MethotrexateMethotrexate results in increased expression of ENO3 mRNA24449571
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of ENO3 mRNA23103053
D008767Methylmercury CompoundsMethylmercury Compounds results in decreased expression of ENO3 mRNA20039754
D008767Methylmercury CompoundsMethylmercury Compounds results in increased expression of ENO3 mRNA27544571
C523799MRK 003ENO3 results in increased susceptibility to MRK 00319903844
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ENO3 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ENO3 mRNA"25554681
D009525NiacinLEPR gene mutant form promotes the reaction [[Niacin binds to Chromium] which results in increased expression of ENO3 mRNA]16940432
C029938nickel sulfatenickel sulfate affects the expression of ENO3 mRNA12718980
D009534NiclosamideNiclosamide results in decreased expression of ENO3 mRNA22576131
D009578NitrobenzenesNitrobenzenes analog results in increased expression of ENO3 mRNA19784758
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ENO3 mRNA27935865
C464660obeticholic acidobeticholic acid results in increased expression of ENO3 mRNA27939613
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of ENO3 mRNA25729387
D010081OxazoloneOxazolone results in increased expression of ENO3 mRNA11379042
D010126OzoneOzone results in decreased expression of ENO3 mRNA12763052
D010269ParaquatParaquat affects the expression of ENO3 mRNA25064622
D052638Particulate MatterParticulate Matter results in decreased expression of ENO3 mRNA24769257
C008776pelargonic acidpelargonic acid results in decreased expression of ENO3 mRNA11379042
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of ENO3 mRNA23427857
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of ENO3 mRNA23427857
D010656PhenylephrinePhenylephrine results in increased expression of ENO3 mRNA18158353
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of ENO3 mRNA26272509
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ENO3 mRNA27935865
C006253pirinixic acidpirinixic acid results in increased expression of ENO3 mRNA17426115
C005556propionaldehydepropionaldehyde results in increased expression of ENO3 mRNA26079696
C059514resveratrolresveratrol results in decreased expression of ENO3 mRNA15582268
C089730rosiglitazonerosiglitazone affects the expression of ENO3 protein21347706
D012838SilymarinSilymarin results in decreased expression of ENO3 mRNA22386810
C080703SK&F 83959SK&F 83959 results in decreased expression of ENO3 protein25852303
C009277sodium arsenatesodium arsenate results in increased expression of ENO3 mRNA21795629
C017947sodium arsenitesodium arsenite affects the expression of ENO3 mRNA23648393
C017947sodium arsenitesodium arsenite results in increased expression of ENO3 mRNA23648393
D053260SootSoot results in increased expression of ENO3 mRNA26551751
C020806tetrabromobisphenol A"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in decreased expression of ENO3 protein"18258299
C020806tetrabromobisphenol A"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in increased expression of ENO3 protein"18258299
C555802tetrabromobisphenol-S-bis(2,3-dibromopropyl ether)"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in decreased expression of ENO3 protein"18258299
C555802tetrabromobisphenol-S-bis(2,3-dibromopropyl ether)"[2,2',3,4,4',5',6-heptabromodiphenyl ether co-treated with hexabromocyclododecane co-treated with tetrabromobisphenol A co-treated with tetrabromobisphenol-S-bis(2,3-dibromopropyl ether) co-treated with hexabromobenzene] results in increased expression of ENO3 protein"18258299
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ENO3 mRNA21632981
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ENO3 mRNA21570461|2637764
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ENO3 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ENO3 mRNA21354282
D013752TetracyclineTetracycline affects the expression of ENO3 mRNA25064622
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ENO3 mRNA25613284
D019284ThapsigarginThapsigargin results in increased expression of ENO3 mRNA22378314
D013849ThimerosalThimerosal results in decreased expression of ENO3 mRNA27188386
D013853ThioacetamideThioacetamide affects the expression of ENO3 mRNA25064622
D013853ThioacetamideThioacetamide results in increased expression of ENO3 mRNA19784758
C009495titanium dioxidetitanium dioxide results in decreased expression of ENO3 mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of ENO3 mRNA20133372
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of ENO3 mRNA25729387
D019772TopotecanTopotecan results in increased expression of ENO3 mRNA25729387
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of ENO3 mRNA24935251|2627250
C012589trichostatin Atrichostatin A results in decreased expression of ENO3 mRNA15901671
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of ENO3 mRNA29024780
D014520UrethaneUrethane results in decreased expression of ENO3 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of ENO3 mRNA25064622
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ENO3 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of ENO3 mRNA26272509|2800136
D014635Valproic AcidValproic Acid results in decreased expression of ENO3 mRNA15901671
C025643vinclozolinvinclozolin results in decreased expression of ENO3 mRNA23869203
D055549Volatile Organic CompoundsVolatile Organic Compounds affects the expression of ENO3 mRNA20823639
C111237vorinostatvorinostat results in increased expression of ENO3 mRNA27188386
D015032ZincZinc deficiency results in decreased expression of ENO3 mRNA19111725
D019287Zinc SulfateZinc Sulfate affects the expression of ENO3 protein25162517

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000287magnesium ion binding-IEA-  
GO:0004634phosphopyruvate hydratase activity-TAS-  
GO:0042803protein homodimerization activity-IEA-  
GO:0046982protein heterodimerization activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006094gluconeogenesis-TAS-  
GO:0007568aging-IEA-  
GO:0042493response to drug-IEA-  
GO:0043403skeletal muscle tissue regeneration-IEA-  
GO:0061621canonical glycolysis-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000015phosphopyruvate hydratase complex-IEA-  
GO:0005615extracellular space-HDA22664934  
GO:0005829cytosol-IDA-  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-IDA-  
GO:0016020membrane-IDA19433310  
GO:0070062extracellular exosome-HDA23533145  
KEGG ID KEGG Term
hsa00010Glycolysis / Gluconeogenesis
hsa01100Metabolic pathways
hsa03018RNA degradation
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-70171GlycolysisTAS
R-HSA-70263GluconeogenesisTAS
R-HSA-70326Glucose metabolismTAS
R-HSA-71387Metabolism of carbohydratesTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20823639Changes in oxidative stress biomarker and gene expression levels in workers exposed to volatile organic compounds. (2011)Kim JHInd Health