Gene info: ID 206338

Gene: LVRN

GENE ID: 206338

Synonyms: APQ|AQPEP|TAQPEP

Description: laeverin

Gene type: protein-coding

Location: 5q23.1

dbXrefs: Ensembl:ENSG00000172901 MIM:610046 Vega:OTTHUMG00000128890 UniprotKB:Q6Q4G3

RefSeq: NC_000005.10

Retrived from: SNP Mapped

SNPs: 1 ANCO-SNPs

Phenotype: AD

# Publications: 0

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 7.266e-2 (AD) 5.647e-1 (ND)

ANCO-SNPs

SNP ID	Position	Alleles	Trait	Variation Type
rs1529442	chr5:116013678 (GRCh38.p7)	C>T	alcohol dependence	SNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
D001151	Arsenic	Arsenic affects the methylation of LVRN gene	25304211
C015001	arsenite	arsenite results in increased methylation of LVRN promoter	23974009
C006780	bisphenol A	bisphenol A results in decreased expression of LVRN mRNA	25181051
D016572	Cyclosporine	Cyclosporine results in increased expression of LVRN mRNA	20106945
D019813	1,2-Dimethylhydrazine	"[APC protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of LVRN mRNA"	27840820
C004312	glycidol	glycidol results in decreased expression of LVRN mRNA	24915197
D009532	Nickel	Nickel results in decreased expression of LVRN mRNA	24768652\|2558310
D011441	Propylthiouracil	Propylthiouracil results in increased expression of LVRN mRNA	24780913

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0008270	zinc ion binding	-	IBA	21873635
GO:0042277	peptide binding	-	IBA	21873635
GO:0070006	metalloaminopeptidase activity	-	IBA	21873635

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0006508	proteolysis	-	IBA	21873635
GO:0007165	signal transduction	-	IBA	21873635
GO:0008217	regulation of blood pressure	-	IBA	21873635
GO:0043171	peptide catabolic process	-	IBA	21873635

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005737	cytoplasm	-	IBA	21873635
GO:0005886	plasma membrane	-	IBA	21873635
GO:0016021	integral component of membrane	-	IEA	-

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal