Gene: ERCC1

2067
COFS4|RAD10|UV20
ERCC excision repair 1, endonuclease non-catalytic subunit
protein-coding
19q13.32
Ensembl:ENSG00000012061 MIM:126380 Vega:OTTHUMG00000182121 UniprotKB:P07992
NG_015839.2
PubMed
ND
69   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.739e-1 (AD)  5.666e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PREB0.921
PSMB40.917
DDX560.916
STOML20.915
EIF3I0.915
ARPC40.913
RAD23A0.912
POLDIP20.91
EIF3B0.91
PPM1G0.906

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.812
OR4F29-0.757
MTRNR2L6-0.214
MTRNR2L9-0.206
HMHB1-0.198
OR6C74-0.196
MTRNR2L10-0.186
RNASE8-0.173
VNN3-0.173
C9orf153-0.172

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ERCC1 mRNA"26808241
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of ERCC1 mRNA"28712647
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of ERCC1 mRNA"21346803
C0495842-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine"2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in decreased expression of ERCC1 mRNA"22100608
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in decreased expression of ERCC1 mRNA"22100608
C0268323,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz(a)anthracene"3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz(a)anthracene results in increased expression of ERCC1 mRNA"22236718
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 protein]22228707
C0251603-aminobenzamide3-aminobenzamide results in decreased expression of ERCC1 mRNA22228707
C0251603-aminobenzamide3-aminobenzamide results in decreased expression of ERCC1 protein22228707
C0251603-aminobenzamide3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]22228707
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [resveratrol results in increased expression of ERCC1 mRNA]23912706
C0909424-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [resveratrol results in increased expression of ERCC1 protein]23912706
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ERCC1 mRNA"27188386
C0352074-amino-2,6-dinitrotoluene"4-amino-2,6-dinitrotoluene affects the expression of ERCC1 mRNA"21346803
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in decreased expression of ERCC1 mRNA19191707
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ERCC1 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of ERCC1 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of ERCC1 mRNA22100608
C059765amphotericin B, deoxycholate drug combination"amphotericin B, deoxycholate drug combination results in increased expression of ERCC1 mRNA"22863853
D001151ArsenicArsenic results in decreased expression of ERCC1 mRNA12569548|1688252
D001151ArsenicArsenic results in decreased expression of ERCC1 protein16882524
D001151ArsenicArsenic results in increased expression of ERCC1 mRNA19661343
D017636Asbestos, Amphibole"Asbestos, Amphibole results in increased expression of ERCC1 protein"20855422
D001379AzathioprineAzathioprine results in increased expression of ERCC1 mRNA22623647
C030935benz(a)anthracenebenz(a)anthracene results in increased expression of ERCC1 mRNA22236718
D001554BenzeneBenzene affects the expression of ERCC1 mRNA16188086
C043931benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA"ERCC1 gene polymorphism results in increased abundance of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA"23203453
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of ERCC1 mRNA20624995
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ERCC1 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ERCC1 protein19748547
D001564Benzo(a)pyreneERCC1 protein affects the susceptibility to Benzo(a)pyrene22382310
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ERCC1 mRNA22228805|2264161
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of ERCC1 mRNA21774909
D001564Benzo(a)pyreneERCC1 protein affects the reaction [BRCA1 protein affects the susceptibility to Benzo(a)pyrene]21507987
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of ERCC1 mRNA"19150397
D004958EstradiolEstradiol results in decreased expression of ERCC1 mRNA24349563
D004958Estradioldecitabine inhibits the reaction [Estradiol results in decreased expression of ERCC1 mRNA]22082530
D004958EstradiolEstradiol results in decreased expression of ERCC1 mRNA22082530
C006780bisphenol Abisphenol A results in increased expression of ERCC1 mRNA25181051
D001761Bleomycin[ERCC4 protein binds to ERCC1 protein] which results in increased susceptibility to Bleomycin22007867
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ERCC1 mRNA22112500|2647268
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ERCC1 protein22112500
D019256Cadmium Chloride[Cadmium Chloride results in increased activity of [DNMT1 protein co-treated with DNMT3A protein]] which results in decreased expression of ERCC1 mRNA22112500
D019256Cadmium Chloride[Cadmium Chloride results in increased activity of [DNMT1 protein co-treated with DNMT3A protein]] which results in increased methylation of ERCC1 promoter22112500
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ERCC1 protein26220685
D019256Cadmium ChlorideCadmium Chloride results in increased methylation of ERCC1 promoter22112500
D019256Cadmium Chloridedecitabine inhibits the reaction [Cadmium Chloride results in decreased expression of ERCC1 mRNA]22112500
D019256Cadmium Chloridedecitabine inhibits the reaction [Cadmium Chloride results in decreased expression of ERCC1 protein]22112500
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of ERCC1 mRNA15501611
D019256Cadmium ChlorideCadmium Chloride results in increased expression of ERCC1 mRNA11958953
D019256Cadmium ChlorideMT1 affects the reaction [Cadmium Chloride results in increased expression of ERCC1 mRNA]11958953
D019256Cadmium ChlorideMT2 affects the reaction [Cadmium Chloride results in increased expression of ERCC1 mRNA]11958953
D002166CamptothecinCamptothecin results in decreased expression of ERCC1 mRNA24792648
D002166CamptothecinERCC1 protein promotes the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AFX protein]]21227924
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of ERCC1 mRNA15056808
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC1 gene20938992
C530333cis-diammine(pyridine)chloroplatinum(II)cis-diammine(pyridine)chloroplatinum(II) results in decreased expression of ERCC1 mRNA21750216
D003035Cobalt[Cobalt co-treated with Organometallic Compounds] results in increased expression of ERCC1 mRNA22147119
D003035CobaltCobalt results in increased expression of ERCC1 mRNA22147119
C018021cobaltous chloridecobaltous chloride results in decreased expression of ERCC1 mRNA19320972|1937684
C018021cobaltous chloridecobaltous chloride results in increased expression of ERCC1 mRNA24386269
D019327Copper SulfateCopper Sulfate results in increased expression of ERCC1 mRNA19549813
C029892cupric chloridecupric chloride results in increased expression of ERCC1 protein22699969
D003474CurcuminCurcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
D003474CurcuminCurcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein]22228707
D003474CurcuminCurcumin results in decreased expression of ERCC1 mRNA17596214|2149372
D003474CurcuminCurcumin results in decreased expression of ERCC1 protein21493726|2222870
D003474Curcumin[Curcumin results in decreased expression of ERCC1 protein] which results in increased susceptibility to Cisplatin21493726
D003474CurcuminCurcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]22228707
D003520CyclophosphamideCyclophosphamide affects the expression of ERCC1 mRNA11906922
D016572CyclosporineCyclosporine results in increased expression of ERCC1 mRNA20106945
C093628cyproconazole[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ERCC1 mRNA29038839
C014347decitabinedecitabine inhibits the reaction [Cadmium Chloride results in decreased expression of ERCC1 mRNA]22112500
C014347decitabinedecitabine inhibits the reaction [Cadmium Chloride results in decreased expression of ERCC1 protein]22112500
C014347decitabinedecitabine inhibits the reaction [Estradiol results in decreased expression of ERCC1 mRNA]22082530
C014347decitabinedecitabine results in decreased expression of ERCC1 mRNA22082530
D002945CisplatinERCC1 protein results in increased susceptibility to Cisplatin21324906
D002945CisplatinCisplatin affects the expression of ERCC1 mRNA21750216
D002945CisplatinCisplatin affects the expression of ERCC1 protein24799992
D002945Cisplatin[Cisplatin co-treated with Fluorouracil] results in decreased expression of ERCC1 mRNA15737843
D002945CisplatinCisplatin results in increased expression of ERCC1 mRNA21165580|2131508
D002945CisplatinCisplatin results in increased expression of ERCC1 protein21315089|2199673
D002945Cisplatin[Curcumin results in decreased expression of ERCC1 protein] which results in increased susceptibility to Cisplatin21493726
D002945CisplatinDUSP6 inhibits the reaction [Cisplatin results in increased expression of ERCC1 mRNA]21996734
D002945CisplatinERCC1 gene polymorphism affects the susceptibility to [Cisplatin co-treated with S 1 (combination)]21364592
D002945CisplatinERCC1 gene polymorphism affects the susceptibility to [gefitinib co-treated with Cisplatin]21264830
D002945CisplatinERCC1 gene SNP results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]21286668
D002945CisplatinERCC1 mRNA affects the susceptibility to [Cisplatin co-treated with Fluorouracil]15173087
D002945CisplatinERCC1 mutant form inhibits the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]]21875941
D002945CisplatinERCC1 mutant form inhibits the reaction [TP53 mutant form promotes the reaction [Cisplatin results in increased phosphorylation of H2AFX protein]]21875941
D002945CisplatinERCC1 mutant form promotes the reaction [RRM2 mutant form promotes the reaction [TP53 mutant form results in increased susceptibility to Cisplatin]]21875941
D002945Cisplatin[ERCC1 protein binds to ERCC4 protein] which results in decreased susceptibility to Cisplatin21357694
D002945CisplatinERCC1 protein results in decreased susceptibility to Cisplatin21093896|2131508
D002945CisplatinERCC1 protein results in increased susceptibility to Cisplatin21076943
D002945CisplatinERCC1 results in decreased susceptibility to Cisplatin21621119
D002945CisplatinPD 0325901 inhibits the reaction [Cisplatin results in increased expression of ERCC1 mRNA]21996734
D002945CisplatinPD 0325901 inhibits the reaction [Cisplatin results in increased expression of ERCC1 protein]21996734
D002945Cisplatin[sodium arsenite co-treated with Cisplatin] results in increased expression of ERCC1 protein21696631
D002945CisplatinERCC1 results in decreased susceptibility to Cisplatin21722328
D002945CisplatinCisplatin results in increased expression of ERCC1 mRNA26739623
D002945CisplatinLovastatin promotes the reaction [Cisplatin results in increased expression of ERCC1 mRNA]26739623
C036042dicyclohexyl phthalatedicyclohexyl phthalate results in increased expression of ERCC1 mRNA26924002
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA"23717041
D0151279,10-Dimethyl-1,2-benzanthracene"[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
D0151279,10-Dimethyl-1,2-benzanthracene"epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
D0151279,10-Dimethyl-1,2-benzanthracene"[theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
C024629dimethyl phthalatedimethyl phthalate results in increased expression of ERCC1 mRNA26924002
D004317DoxorubicinDoxorubicin results in increased expression of ERCC1 mRNA22712078
D004785Environmental PollutantsERCC1 gene SNP affects the susceptibility to Environmental Pollutants24036326
C045651epigallocatechin gallate"[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
C045651epigallocatechin gallate"epigallocatechin gallate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
C109476epoxiconazole[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ERCC1 mRNA29038839
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ERCC1 mRNA17942748
D018120FinasterideFinasteride results in increased expression of ERCC1 mRNA24136188
C007738fluoranthene[fluoranthene co-treated with Permethrin] results in increased expression of ERCC1 mRNA22406618
D005472Fluorouracil[Cisplatin co-treated with Fluorouracil] results in decreased expression of ERCC1 mRNA15737843
D005472FluorouracilERCC1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]15213713|1844832
D005472FluorouracilERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]17401013
D005472FluorouracilERCC1 gene SNP results in increased susceptibility to [Cisplatin co-treated with Fluorouracil]21286668
D005472FluorouracilERCC1 mRNA affects the susceptibility to [Cisplatin co-treated with Fluorouracil]15173087
D005472FluorouracilFluorouracil results in decreased expression of ERCC1 mRNA17016597
D005485FlutamideFlutamide results in increased expression of ERCC1 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC1 gene20938992
D004397FonofosERCC1 polymorphism affects the susceptibility to Fonofos22102698
D005557FormaldehydeERCC1 gene mutant form results in increased susceptibility to Formaldehyde22186232
D002955LeucovorinERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]17401013
C039281furanfuran results in increased expression of ERCC1 mRNA22079235
C419708gefitinibERCC1 gene polymorphism affects the susceptibility to gefitinib21264830
C419708gefitinibERCC1 gene polymorphism affects the susceptibility to [gefitinib co-treated with Cisplatin]21264830
D005947Glucose3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
D005947Glucose3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 protein]22228707
D005947GlucoseCurcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
D005947GlucoseCurcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein]22228707
D005947GlucoseERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]22228707
D005947GlucoseERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 mRNA]22228707
D005947GlucoseERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 protein]22228707
D005947GlucoseERCC1 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]22228707
D005947GlucoseERCC1 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]22228707
D005947GlucoseERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
D005947GlucoseERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 protein]22228707
D005947GlucoseGlucose results in increased expression of ERCC1 mRNA22228707
D005947GlucoseGlucose results in increased expression of ERCC1 protein22228707
D005947Glucosetrichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
D005947Glucosetrichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 protein]22228707
D017313FenretinideFenretinide results in increased expression of ERCC1 protein15059897
D017313FenretinideFenretinide results in increased expression of ERCC1 mRNA28973697
D006861Hydrogen PeroxideERCC1 protein affects the susceptibility to Hydrogen Peroxide22007867
D006861Hydrogen Peroxide[ERCC4 protein binds to ERCC1 protein] which results in increased susceptibility to Hydrogen Peroxide22007867
C051890irinotecanirinotecan results in decreased expression of ERCC1 protein11593056
C017461lead nitratelead nitrate affects the reaction [ERCC1 affects the expression of MT1 mRNA]11891201
C017461lead nitratelead nitrate affects the reaction [ERCC1 affects the expression of MT2 mRNA]11891201
D001556LindaneLindane results in increased expression of ERCC1 mRNA24349563
D008070Lipopolysaccharides[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of ERCC1 mRNA22777745
D018021Lithium ChlorideLithium Chloride results in increased expression of ERCC1 mRNA15711924
D008148LovastatinLovastatin promotes the reaction [Cisplatin results in increased expression of ERCC1 mRNA]26739623
D008148LovastatinLovastatin results in increased expression of ERCC1 mRNA26739623
D008550MelatoninMelatonin results in increased expression of ERCC1 protein24799992
D058955MetalloidsERCC1 gene SNP affects the susceptibility to Metalloids24036326
D008670MetalsERCC1 gene SNP affects the susceptibility to Metals24036326
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ERCC1 gene20938992
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ERCC1 mRNA20375079
C008493methylselenic acidmethylselenic acid results in increased expression of ERCC1 mRNA12517777
C063855microcystin RRmicrocystin RR results in decreased expression of ERCC1 protein19111056
C517284monomethyl phthalatemonomethyl phthalate results in increased expression of ERCC1 mRNA26924002
C005246myristicinmyristicin results in decreased expression of ERCC1 mRNA24792648
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of ERCC1 mRNA"25554681
C484027oligofectamineoligofectamine results in increased expression of ERCC1 mRNA14668052
D009942Organometallic Compounds[Cobalt co-treated with Organometallic Compounds] results in increased expression of ERCC1 mRNA22147119
C030110oxaliplatinERCC1 gene polymorphism affects the susceptibility to [Fluorouracil co-treated with oxaliplatin]15213713|1844832
C030110oxaliplatinERCC1 gene polymorphism affects the susceptibility to oxaliplatin20979931
C030110oxaliplatinERCC1 gene SNP affects the susceptibility to [Fluorouracil co-treated with Leucovorin co-treated with oxaliplatin]17401013
C030110oxaliplatinERCC1 protein affects the susceptibility to oxaliplatin15041737|1565554
C030110oxaliplatinoxaliplatin results in increased expression of ERCC1 mRNA16773204
D010269Paraquat[ERCC4 protein binds to ERCC1 protein] which results in increased susceptibility to Paraquat22007867
D010269ParaquatParaquat affects the splicing of ERCC1 mRNA23613995
D052638Particulate MatterParticulate Matter affects the expression of ERCC1 mRNA12919963
D052638Particulate MatterParticulate Matter results in increased expression of ERCC1 mRNA12937889
C506614PD 0325901PD 0325901 inhibits the reaction [Cisplatin results in increased expression of ERCC1 mRNA]21996734
C506614PD 0325901PD 0325901 inhibits the reaction [Cisplatin results in increased expression of ERCC1 protein]21996734
C506614PD 0325901PD 0325901 results in decreased expression of ERCC1 mRNA21996734
D000068437PemetrexedPemetrexed inhibits the reaction [resveratrol results in increased stability of and results in increased expression of ERCC1 mRNA]23912706
D000068437PemetrexedPemetrexed inhibits the reaction [resveratrol results in increased stability of and results in increased expression of ERCC1 protein]23912706
D000068437PemetrexedPemetrexed results in decreased expression of ERCC1 mRNA23912706
D000068437PemetrexedPemetrexed results in decreased expression of ERCC1 protein23912706
D000068437PemetrexedMAP2K6 protein mutant form inhibits the reaction [Pemetrexed inhibits the reaction [resveratrol results in increased expression of ERCC1 protein]]23912706
D026023Permethrin[fluoranthene co-treated with Permethrin] results in increased expression of ERCC1 mRNA22406618
D026023PermethrinPermethrin results in decreased expression of ERCC1 mRNA22406618
D026023PermethrinPermethrin results in increased expression of ERCC1 mRNA22406618
D010862PilocarpinePilocarpine results in increased expression of ERCC1 mRNA17971868
C049032pinosylvinpinosylvin results in increased expression of ERCC1 mRNA23333577
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ERCC1 mRNA19710929
D010984PlatinumERCC1 protein affects the susceptibility to Platinum15788669
C043435polylactic acid-polyglycolic acid copolymer"[epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
C043435polylactic acid-polyglycolic acid copolymer"[theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
C045362prochloraz[cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of ERCC1 mRNA29038839
C031280pyrazolepyrazole results in increased expression of ERCC1 mRNA17945193
D011794QuercetinQuercetin results in increased expression of ERCC1 mRNA21632981
C012526quercitrinquercitrin results in decreased expression of ERCC1 mRNA25193878
D017382Reactive Oxygen Species[ERCC4 protein binds to ERCC1 protein] which results in decreased activity of Reactive Oxygen Species22007867
C059514resveratrol4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [resveratrol results in increased expression of ERCC1 mRNA]23912706
C059514resveratrol4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [resveratrol results in increased expression of ERCC1 protein]23912706
C059514resveratrolERCC1 protein affects the susceptibility to resveratrol23912706
C059514resveratrolPemetrexed inhibits the reaction [resveratrol results in increased stability of and results in increased expression of ERCC1 mRNA]23912706
C059514resveratrolPemetrexed inhibits the reaction [resveratrol results in increased stability of and results in increased expression of ERCC1 protein]23912706
C059514resveratrolresveratrol results in increased stability of and results in increased expression of ERCC1 mRNA23912706
C059514resveratrolresveratrol results in increased stability of and results in increased expression of ERCC1 protein23912706
C059514resveratrolMAP2K6 protein mutant form inhibits the reaction [Pemetrexed inhibits the reaction [resveratrol results in increased expression of ERCC1 protein]]23912706
D015474IsotretinoinIsotretinoin results in decreased expression of ERCC1 mRNA20436886
C547185riccardin Driccardin D results in decreased expression of ERCC1 mRNA24069304
C079198S 1 (combination)ERCC1 gene polymorphism affects the susceptibility to [Cisplatin co-treated with S 1 (combination)]21364592
C093642SB 203580SB 203580 inhibits the reaction [tanshinone results in decreased expression of ERCC1 mRNA]21165580
C093642SB 203580SB 203580 results in increased expression of ERCC1 mRNA21165580
D012643SeleniumSelenium results in increased expression of ERCC1 mRNA19244175
C009277sodium arsenatesodium arsenate results in increased expression of ERCC1 mRNA11353140
C017947sodium arsenite[sodium arsenite co-treated with Cisplatin] results in increased expression of ERCC1 protein21696631
C017947sodium arsenitesodium arsenite results in decreased expression of ERCC1 mRNA21776218
C017947sodium arsenitesodium arsenite results in increased expression of ERCC1 mRNA11353140
C016104sodium bichromatesodium bichromate results in decreased expression of ERCC1 mRNA17685462
D018038Sodium SeleniteSodium Selenite results in increased expression of ERCC1 mRNA18175754
D013311Streptozocin3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]22228707
D013311StreptozocinCurcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]22228707
D013311StreptozocinStreptozocin results in increased expression of ERCC1 mRNA22228707
D013311StreptozocinStreptozocin results in increased expression of ERCC1 protein22228707
C021751tanshinoneSB 203580 inhibits the reaction [tanshinone results in decreased expression of ERCC1 mRNA]21165580
C021751tanshinonetanshinone results in decreased expression of ERCC1 mRNA21165580
C020806tetrabromobisphenol Atetrabromobisphenol A results in increased expression of ERCC1 mRNA25172293
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ERCC1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ERCC1 mRNA17942748
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to ERCC1 promoter]19654925
C056068theaflavin"[theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ERCC1 mRNA]"23717041
C012589trichostatin Atrichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]22228707
C012589trichostatin Atrichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 protein]22228707
C012589trichostatin Atrichostatin A results in decreased expression of ERCC1 mRNA22228707
C012589trichostatin Atrichostatin A results in decreased expression of ERCC1 protein22228707
C073339usnic acid[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of ERCC1 mRNA22777745
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ERCC1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of ERCC1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of ERCC1 mRNA26272509
D014635Valproic AcidValproic Acid affects the expression of ERCC1 mRNA17292431
D014640VancomycinVancomycin results in decreased expression of ERCC1 mRNA18930951
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of ERCC1 gene25560391
D001335Vehicle EmissionsVehicle Emissions affects the expression of ERCC1 mRNA12919963
D001335Vehicle EmissionsVehicle Emissions results in increased expression of ERCC1 mRNA12937889
C521013veliparibERCC1 protein promotes the reaction [veliparib promotes the reaction [Camptothecin results in increased expression of H2AFX protein]]21227924
C025643vinclozolinvinclozolin results in decreased expression of ERCC1 mRNA23034163
D014810Vitamin EVitamin E results in increased expression of ERCC1 mRNA19244175
C108830Y 27632Y 27632 results in increased expression of ERCC1 mRNA20878077
D015032ZincZinc results in increased expression of ERCC1 mRNA15226459
D019287Zinc SulfateZinc Sulfate results in increased expression of ERCC1 mRNA15226459

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000014single-stranded DNA endodeoxyribonuclease activity-IBA21873635  
GO:0000014single-stranded DNA endodeoxyribonuclease activitycontributes_toIDA7559382  
GO:0001094TFIID-class transcription factor binding-IEA-  
GO:0003677DNA bindingcontributes_toIDA14734547  
GO:0003684damaged DNA binding-IBA21873635  
GO:0003684damaged DNA binding-IDA17720715  
GO:0003697single-stranded DNA binding-IBA21873635  
GO:0003697single-stranded DNA binding-IDA16076955  17720715  
GO:0005515protein binding-IPI7559382  8197175  9013642  11058119  14690602  14706347  
16189514  16338413  16491090  16756962  17055345  17289582  
18812185  19596235  19596236  24780295  25416956  
GO:0008022protein C-terminus binding-IPI9722633  
GO:0019904protein domain specific binding-IPI17720715  
GO:19905993' overhang single-stranded DNA endodeoxyribonuclease activitycontributes_toIMP14690602  
GO ID GO Term Qualifier Evidence PubMed
GO:0000710meiotic mismatch repair-IBA21873635  
GO:0000720pyrimidine dimer repair by nucleotide-excision repair-IEA-  
GO:0001302replicative cell aging-IEA-  
GO:0006281DNA repair-IMP25538220  
GO:0006283transcription-coupled nucleotide-excision repair-TAS-  
GO:0006289nucleotide-excision repair-IDA3290851  
GO:0006289nucleotide-excision repair-IGI11707424  
GO:0006293nucleotide-excision repair, preincision complex stabilization-TAS-  
GO:0006295nucleotide-excision repair, DNA incision, 3'-to lesion-IMP7657672  
GO:0006296nucleotide-excision repair, DNA incision, 5'-to lesion-IBA21873635  
GO:0006296nucleotide-excision repair, DNA incision, 5'-to lesion-IMP7657672  
GO:0006296nucleotide-excision repair, DNA incision, 5'-to lesion-TAS-  
GO:0006303double-strand break repair via nonhomologous end joining-IMP14690602  
GO:0006310DNA recombination-IGI11707424  
GO:0006312mitotic recombination-IBA21873635  
GO:0006312mitotic recombination-IMP8811092  
GO:0006949syncytium formation-IEA-  
GO:0006979response to oxidative stress-IMP9256505  17614221  
GO:0007283spermatogenesis-IEA-  
GO:0007584response to nutrient-IEA-  
GO:0008283cell proliferation-IEA-  
GO:0008584male gonad development-IEA-  
GO:0009650UV protection-IEA-  
GO:0009744response to sucrose-IEA-  
GO:0010165response to X-ray-IEA-  
GO:0010259multicellular organism aging-IEA-  
GO:0032205negative regulation of telomere maintenance-IMP17055345  
GO:0033683nucleotide-excision repair, DNA incision-TAS-  
GO:0035166post-embryonic hemopoiesis-IEA-  
GO:0035264multicellular organism growth-IEA-  
GO:0035902response to immobilization stress-IEA-  
GO:0036297interstrand cross-link repair-TAS-  
GO:0045190isotype switching-IEA-  
GO:0046686response to cadmium ion-IEA-  
GO:0048477oogenesis-IEA-  
GO:0048568embryonic organ development-IEA-  
GO:0061819telomeric DNA-containing double minutes formation-IMP14690602  
GO:0070911global genome nucleotide-excision repair-TAS-  
GO:0070914UV-damage excision repair-IBA21873635  
GO:0090656t-circle formation-ISS-  
GO:1904431positive regulation of t-circle formation-ISS-  
GO:1905765negative regulation of protection from non-homologous end joining at telomere-IMP14690602  
GO ID GO Term Qualifier Evidence PubMed
GO:0000109nucleotide-excision repair complex-IDA3290851  7559382  8197175  
GO:0000110nucleotide-excision repair factor 1 complex-IBA21873635  
GO:0000110nucleotide-excision repair factor 1 complex-IDA10413517  
GO:0000784nuclear chromosome, telomeric region-IDA14690602  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005669transcription factor TFIID complex-IEA-  
GO:0005829cytosol-IDA-  
GO:0070522ERCC4-ERCC1 complex-IBA21873635  
GO:0070522ERCC4-ERCC1 complex-IDA14690602  17055345  
KEGG ID KEGG Term
hsa03420Nucleotide excision repair
Reactome ID Reactome Term Evidence
R-HSA-5685938HDR through Single Strand Annealing (SSA)TAS
R-HSA-5693532DNA Double-Strand Break RepairTAS
R-HSA-5693538Homology Directed RepairTAS
R-HSA-5693567HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)TAS
R-HSA-5696395Formation of Incision Complex in GG-NERTAS
R-HSA-5696398Nucleotide Excision RepairTAS
R-HSA-5696399Global Genome Nucleotide Excision Repair (GG-NER)TAS
R-HSA-5696400Dual Incision in GG-NERTAS
R-HSA-6781827Transcription-Coupled Nucleotide Excision Repair (TC-NER)TAS
R-HSA-6782135Dual incision in TC-NERTAS
R-HSA-6783310Fanconi Anemia PathwayTAS
R-HSA-73894DNA RepairTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
23889225Inter-individual variation of smoking-related DNA adducts in lymphocytes-relationship to mRNA levels for CYP1A1 and DNA repair enzymes. (2000)Ichiba MBiomarkers
29172271Association between ERCC1 Polymorphism and the Risk and Clinicopathological Features of Breast Cancer in Thai Women in the Lower Northeastern Region (2017 Nov 26)Pongsavee MAsian Pac J Cancer Prev
24935625Prognostic and predictive role of ERCC1 protein expression in locally advanced stage III non-small cell lung cancer. (2014 Jul)Sad LMMed Oncol
18451256Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis. (2008 May 1)Yu DClin Cancer Res
21327329Expression of xeroderma pigmentosum complementation group C protein predicts cisplatin resistance in lung adenocarcinoma patients. (2011 May)Lai TCOncol Rep
27668351Study of association between pre-senile cataracts and rs11615 of ERCC1, rs13181 of ERCC2, and rs25487 of XRCC1 polymorphisms in a Spanish population. (2017 Jul-Aug)Lopez-Valverde GOphthalmic Genet
22938424Predictive role of ERCC1 and XPD genetic polymorphisms in survival of Chinese non-small cell lung cancer patients receiving chemotherapy. (2012)Zhang ZYAsian Pac J Cancer Prev
27183913Fine-mapping markers of lung cancer susceptibility in a sub-region of chromosome 19q13.3 among Chinese. (2016 Sep 20)Yin JOncotarget
23336484[Epithelial growth factor receptor mutation status to the effective of survival in non-small cell lung cancer after surgery]. (2012 Dec)Liu YZhonghua Wai Ke Za Zhi
24563277Association of single nucleotide polymorphisms of nucleotide excision repair genes with laryngeal cancer risk and interaction with cigarette smoking and alcohol drinking. (2014 May)Li XTumour Biol
25025378ERCC1 Cys8092Ala and XRCC1 Arg399Gln polymorphisms predict progression-free survival after curative radiotherapy for nasopharyngeal carcinoma. (2014)Jin HPLoS One
22335888A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population. (2012 Jun)Yin JLung Cancer
22002622Nucleotide excision repair gene ERCC1 polymorphisms contribute to cancer susceptibility: a meta-analysis. (2012 Jan)Zhang LMutagenesis
25194563Decreased ERCC1 Expression After Platinum-Based Neoadjuvant Chemotherapy in non-Small Cell Lung Cancer. (2015 Apr)Podmaniczky EPathol Oncol Res
24140460HapMap-based study identifies risk sub-region on chromosome 19q13.3 in relation to lung cancer among Chinese. (2013 Dec)Yin JCancer Epidemiol
23846458ERCC1 protein expression is associated with differential survival in oropharyngeal head and neck squamous cell carcinoma. (2013 Oct)Patel MROtolaryngol Head Neck Surg
16308313DNA repair polymorphisms and cancer risk in non-smokers in a cohort study. (2006 May)Matullo GCarcinogenesis
19444904Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair genes. (2009 Sep 15)Abbasi RInt J Cancer
15734977Gene-smoking interaction associations for the ERCC1 polymorphisms in the risk of lung cancer. (2005 Feb)Zhou WCancer Epidemiol Biomarkers Prev
22093627[EGFR gene copy number, ERCC1 and BRCA1 protein expression and their relationship in non-small cell lung cancer]. (2011 Jul)Deng QHZhonghua Zhong Liu Za Zhi
16103444Expression of nucleotide excision repair proteins in lymphocytes as a marker of susceptibility to squamous cell carcinomas of the head and neck. (2005 Aug)Wei QCancer Epidemiol Biomarkers Prev
21875468[Expression of ERCC1 mRNA and its impact on the prognosis of patients with non-small cell lung cancer]. (2011 May)Ma WZhonghua Zhong Liu Za Zhi
24582975Laryngeal cancer risk and common single nucleotide polymorphisms in nucleotide excision repair pathway genes ERCC1, ERCC2, ERCC3, ERCC4, ERCC5 and XPA. (2014 May 25)Lu BGene
20973062Accelerated aging of intervertebral discs in a mouse model of progeria. (2010 Dec)Vo NJ Orthop Res
16284380Polymorphisms/haplotypes in DNA repair genes and smoking: a bladder cancer case-control study. (2005 Nov)Matullo GCancer Epidemiol Biomarkers Prev
19297315The NER proteins are differentially expressed in ever smokers and in never smokers with lung adenocarcinoma. (2009 Jul)Planchard DAnn Oncol
16537713Genetic variation in the nucleotide excision repair pathway and bladder cancer risk. (2006 Mar)Garcia-Closas MCancer Epidemiol Biomarkers Prev
22740911Single nucleotide polymorphisms in DNA repair genes and risk of cervical cancer: A case-control study. (2012 Feb)Zhang LOncol Lett
16690207Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study. (2007 Mar 8)Vogel UCancer Lett
21216194DNA repair gene polymorphisms and micronucleus frequencies in Chinese workers exposed to vinyl chloride monomer. (2011 Jun)Qiu YLInt J Hyg Environ Health
16806437Nucleotide excision repair genotype and the incidence of endometrial cancer: effect of other risk factors on the association. (2006 Dec)Weiss JMGynecol Oncol
24211096Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. (2014 Mar 1)Nasto LASpine J
23086647[Expression of RRM1 and ERCC1 genes in tumor tissues and peripheral blood lymphocytes of advanced non-small cell lung cancer]. (2012 Sep)Zhang GBZhejiang Da Xue Xue Bao Yi Xue Ban
11900225Expression of nucleotide excision repair genes and the risk for squamous cell carcinoma of the head and neck. (2002 Jan 15)Cheng LCancer
20863778Association studies of excision repair cross-complementation group 1 (ERCC1) haplotypes with lung and head and neck cancer risk in a Caucasian population. (2011 Apr)Jones NRCancer Epidemiol
26617899Association of NER pathway gene polymorphisms with susceptibility to laryngeal cancer in a Chinese population. (2015)Sun YInt J Clin Exp Pathol
18026184NAT2 and NER genetic variants and sporadic prostate cancer susceptibility in African Americans. (2008)Hooker SProstate Cancer Prostatic Dis
24933103Associations of polymorphisms in DNA repair genes and MDR1 gene with chemotherapy response and survival of non-small cell lung cancer. (2014)Du YPLoS One
21942242Association of GSTT1 polymorphism with acute myeloid leukemia risk is dependent on smoking status. (2012 Apr)Kim HNLeuk Lymphoma
10910954Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis. (2000 Aug)Cheng LCarcinogenesis
16679872Effects of ERCC1 expression in peripheral blood on the risk of head and neck cancer. (2006 Jun)Yang MEur J Cancer Prev
23435956Decreased expression of DNA repair genes (XRCC1, ERCC1, ERCC2, and ERCC4) in squamous intraepithelial lesion and invasive squamous cell carcinoma of the cervix. (2013 May)Bajpai DMol Cell Biochem
22044695Genetic variants associated with the risk of chronic obstructive pulmonary disease with and without lung cancer. (2012 Mar)de Andrade MCancer Prev Res (Phila)
16364765Lack of association between DNA repair gene ERCC1 polymorphism and risk of lung cancer in a Chinese population. (2006 Jan 1)Yin JCancer Genet Cytogenet
26681190Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population. (2015)Xue PPLoS One
21426588High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area. (2011 Mar 23)Chiu TJJ Transl Med
21601580HapMap-based study of a region encompassing ERCC1 and ERCC2 related to lung cancer susceptibility in a Chinese population. (2011 Aug 1)Yin JMutat Res
24667263[Clinicopathological and prognostic significance of a panel of tumor biomarkers in lung adenocarcinoma: a tissue microarray study]. (2014 Mar)Yang XZhongguo Fei Ai Za Zhi
24841208Association studies of ERCC1 polymorphisms with lung cancer susceptibility: a systematic review and meta-analysis. (2014)Zhu JPLoS One
28464886A lung cancer risk classifier comprising genome maintenance genes measured in normal bronchial epithelial cells. (2017 May 2)Yeo JBMC Cancer
23147699Association of genetic polymorphisms in ERCC1 and ERCC2/XPD with risk of chronic benzene poisoning in a Chinese occupational population. (2013 Feb 18)Xiao SMutat Res
24994038Mutations of EGFR or KRAS and expression of chemotherapy-related genes based on small biopsy samples in stage IIIB and IV inoperable non-small cell lung cancer. (2014 Dec)Deng LLJ Cancer Res Clin Oncol
17303907Effect of ERCC1 polymorphisms and the modification by smoking on the survival of non-small cell lung cancer patients. (2006)Park SYMed Oncol
22415779p38 Mitogen-activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients. (2012 Oct 15)Planchard DCancer
20731898[Relationship between polymorphisms of DNA repair gene ERCC1 and susceptibility to lung cancer.]. (2008 Apr 20)Zhang ZZhongguo Fei Ai Za Zhi
18386788Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma. (2008 Jul 1)Doecke JInt J Cancer
25667646Association between epidermal growth factor receptor mutations and the expression of excision repair cross-complementing protein 1 and ribonucleotide reductase subunit M1 mRNA in patients with non-small cell lung cancer. (2015 Mar)Xu CWExp Ther Med
18289367A haplotype of polymorphisms in ASE-1, RAI and ERCC1 and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a Danish prospective case-cohort study. (2008 Feb 20)Hansen RDBMC Cancer
18615480Association of ERCC1 polymorphisms and susceptibility to nasopharyngeal carcinoma. (2009 Mar)Yang ZHMol Carcinog
20003463Association between polymorphisms in DNA repair genes and survival of non-smoking female patients with lung adenocarcinoma. (2009 Dec 15)Yin ZBMC Cancer
26033827Genetic variation affects congenital heart defect susceptibility in offspring exposed to maternal tobacco use. (2015 Oct)Tang XBirth Defects Res A Clin Mol Teratol
18544627Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk. (2008 Jun 15)McWilliams RRCancer Res
16393248Gene-environment interaction involved in oral carcinogenesis: molecular epidemiological study for metabolic and DNA repair gene polymorphisms. (2006 Jan)Sugimura TJ Oral Pathol Med
20003391ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females. (2009 Dec 14)Yin ZJ Exp Clin Cancer Res
19337508Elevated human telomerase reverse transcriptase gene expression in blood cells associated with chronic arsenic exposure in Inner Mongolia, China. (2009 Mar)Mo JEnviron Health Perspect
24313652Classifying squamous cell carcinoma of the head and neck: prognosis, prediction and implications for therapy. (2014 Feb)Weiss JExpert Rev Anticancer Ther
26542178Prognostic value of ERCC1, RRM1, BRCA1 and SETDB1 in early stage of non-small cell lung cancer. (2016 Aug)Lafuente-Sanchis AClin Transl Oncol
17489733Testing for excision repair cross-complementing 1 in patients with non-small-cell lung cancer for chemotherapy response. (2007 May)Felip EExpert Rev Mol Diagn
29581776Association of Smoking and XPG, CYP1A1, OGG1, ERCC5, ERCC1, MMP2, and MMP9 Gene Polymorphisms with the early detection and occurrence of Laryngeal Squamous Carcinoma. (2018)Zhu YJ Cancer